Published: Sept. 28, 2020
Inside cells, DNA is coiled around histone proteins, making spools of nucleosomes. Cynthia Wolberger studies the molecular machines that unwrap the chromatin packing to transcribe or repair genes. The structures …
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Updated: Sept. 8, 2020
Join us for our weekly webinar series --- Tuesdays at 12pm ET hear from developers and scientists about what's new in structural biology. Community members can connect via video, see …
Published: July 31, 2020
Priyamvada Acharya studies how proteins on the surface of HIV move to invade cells and evade the immune system. For many years her research has been focused on the HIV-1 …
Updated: April 29, 2020
Three weeks after most research on campus was paused in the first wave of the U.S. coronavirus pandemic, Yuh Min Chook learned that a cancer drug her group helped develop …
Updated: March 30, 2020
Some things take time and patience. Like generating higher atomic resolution structures from cryo-electron microscopy. Or reconstructing a protein’s hidden coils in atomic models. Or mastering the skills and teamwork …
Updated: March 25, 2020
We've got a couple of operating system alerts for those of you looking to buy new computers or update existing Mac or Linux machines: SBGrid is not compatible with MacOS …
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Published: Feb. 27, 2020
For sports buffs, the end of winter ushers in a new season of competitive delights. Alan Brown’s spring thoughts turn to Formula One and the pre-season test runs of new designs and rampant …
Updated: Jan. 30, 2020
One day soon, the process of collecting data from cryo-electron microscopes may be as automated as it is on synchrotron beamlines. Until then, Guy Schoehn and his team will be busy training and …
Updated: Dec. 18, 2019
A few years ago on a visit to Cape Cod, Michael Rosen was walking along the beach at low tide. He came across a tidal pool set in a giant rock. The pool …
Updated: Sept. 30, 2019
Kissing a frog might not spark a fairy tale ending, but learning how frogs survive some of nature’s most deadly poisons has opened a new chapter in the laboratory of Daniel Minor Jr. …
Published: July 31, 2019
The evolution of SBGrid tracks with advances in structural biology, and cryo-EM is at the forefront of that change. This article reflects on 3 pivotal papers that describe key advances in cryoEM, from …
Published: July 30, 2019
When Marcos Sotomayor explains his research out loud, his voice tickles the topic of his studies. A core biological question in his laboratory addresses how hearing happens at the molecular level. For words …
Updated: June 28, 2019
Hao Wu is a third generation scientist whose formative years were shaped by the Chinese Cultural Revolution. In fact, it’s fair to say the revolution, better known for persecution of academics and intellectuals, …
Updated: June 27, 2019
With the 2017 Nobel Prize, cryo-electron microscopy became briefly famous outside of the growing clutch of scientists using the techniques to capture detailed views of molecules that keep life humming along. The prize …
Updated: June 21, 2019
The Natural Bridge In 2013, Piotr Sliz and the team at SBGrid published a paper in eLife describing, for the first time in a formal, academic fashion, the SBGrid model. In existence since …
Updated: May 29, 2019
The applications listed below are freely available to non-profit labs, but each lab must register individually before we can install the software. If you would like any of these titles included in your …
Updated: May 28, 2019
Watch SBGridTV on YouTube. If you missed any of the webinars from our SBGrid Lunch Break series, featuring software developers introducing new releases, suggesting helpful tips and tricks, or offering a basic tutorial …
Updated: May 28, 2019
When Pawel Penczek took his first job in the lab of Joachim Frank, a pioneer in cryo-Electron Microscopy, he had never heard about the technique. "My interest was in digital signal processing," says …
Updated: May 28, 2019
As an undergraduate at University of Montpellier in France in the early 2000s, Sébastien Granier’s interest in science was stoked by the passionate lectures of a renowned plant physiologist who studied the architecture …