SBGrid is pleased to offer a one-day workshop - CryoEM in Industry: cutting edge, cost-efficient compute alternatives - on June 26, 2025 at Harvard Medical School in Boston. This workshop will focus on innovative and resource-efficient IT architectures for CryoEM, structure prediction and drug discovery in pharmaceutical research.
June 26, 2025
Harvard Medical School, 200 Longwood Ave, Boston, MA 02115
Jason Key and Piotr Sliz
Opening Keynote
- 9:00am: Scientific Rigor in Structural Biology Research - Piotr Sliz, Ph.D., SBGrid PI
Session 1 - 9:30-11:15am: Is it feasible to conduct CryoEM/ET affordably with open source software?
Moderated by Jason Key
- 9:30am: 194 CryoEM Applications in the SBGrid Collection - Jason Key, Ph.D., SBGrid/Harvard
- 9:45am: SCIPION - an open source image processing framework - Demo by Pete Meyer, Ph.D., SBGrid/Harvard
- 10:05am: Meet and greet SCIPION Developers (Zoom) - Carlos Oscar S. Sorzano, Ph.D., NCIS, Madrid
- 10:15am: Deep Reconstructing Generative Networks for cryo-EM and cryo-ET heterogeneous reconstruction - Prof. Joseph H. Davis, MIT
- 10:45am: A Hitchhiker's Guide to Structural CryoET with WARP - Alister Burt, Ph.D., Genentech
- 11:15am: Coffee Break
Session 2 - 11:30-2pm: Is our Current Cloud Setup Addressing our Needs and Offering Value?
Moderated by Sanjoy Ray
- 11:30am: SBCloud - an SBGrid-based integrative AWS compute platform - Ben Eisenbraun, SBGrid/Harvard
- 11:45am: SBCloud - a US-wide pilot with 12 academic laboratories - Piotr Sliz, Ph.D., SBGrid/Harvard
- 12:00pm: Sustaining Cloud-based Environments - Panel with Selected Attendees
- 12:30-2pm: Lunch, Round Table Discussion, and Networking
Session 3 - 2-4pm: From Structure to Therapeutics
Moderated by Woody Sherman
- 2:05pm: STORMM: Structure and TOpology Replica Molecular Mechanics for chemical simulations - Woody Sherman, Ph.D.,Psivant Therapeutics
- 2:30pm: Predictomes: A classifier-curated database of AlphaFold-modeled protein-protein interactions - Ernst Schmidt, Ph.D., Harvard
- 3:00pm: Democratizing Protein-Small Molecule Interaction Modeling with Boltz-1 - Gabrielle Corso, Ph.D., MIT
- 3:30pm: Maximizing Impact of Macromolecular Structure: Can the CryoEM IT infrastructure promote cost-efficient structure analysis & modeling? - Panel with Selected Attendees
- 4:00pm: Closing Remarks and Networking