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SBGridTV

  • The mobile element that conveys methicillin resistance to staph includes a gene that encodes for Cch. Learn more about Phoebe Rice's Chicago lab.

  • AlkD (grey) crystal structure bound to DNA containing 3-deaza-3-methyldeoxyadenosine (light green), from Brandt Eichman. Read the full story.

  • Jalview Developer Geoff Barton's desk with the JalviewAbacus (right) and displayed a dendrogram (tree) for the set of sequences shown in the alignment, using Jalview linked to Chimera. Read the full story here.

  •  Project MAC display system, circa 1965,

    The Project MAC display system, circa 1965. Read more about the history of molecular graphics software and UCSF Chimera in our SBGrid Tale featuring Bob Langridge and Tom Ferrin.

  • You'll find SBGrid in ~350 structural biology labs located at over 100 different institutions in about 20 countries around the world. See full map and read more in eLIFE.

  • Daniel Panne's group, which relocated in 2018 to the University of Leicester, looks at the language of gene regulation and visualizes the catalytic core of p300. Read the full story.

  • Professor Catherine Drennan of MIT

    The SBGrid Consortium provides structural biologists worldwide with access to the software they need to discover the shapes of the molecules of life. Read more in eLIFE.

  • The AdipoR2 structure revealing the presence of a bound fatty acid at a zinc binding site, from Sebastien Granier's lab at the French National Institute of Health and Medical Research (INSERM), Institut de Génomique Fonctionnelle, Montpellier France. Read more.

  • Tom Rapoport's group at Harvard Medical School captured the crystal structure of the active translocon being pushed through the hourglass-shaped SecY protein-conducting channel. You can find out more about the science and learn some personal history in our Member Tale.

  • The first high-resolution (2.8 Å) X-ray crystal structure of the transcription initiation complex of Mycobacterium smegmatis, from the laboratory of Seth Darst at Rockefeller University.

    Image courtesy of E. Campbell.

  • In traditional X-ray crystallography, X-rays bombard 1 crystal 100s of times. This syringe, developed for a dynamic temperature experiment in James Fraser's lab at UCSF, shoots 1,000s of crystals into an X-ray-free electron laser beam, one at a time. Learn more.

    Image courtesy of Alexander Wolff.

Recent Software Updates

Oct 26 | Python

a general-purpose, interpreted, object oriented, high-level dynamic programming language that emphasizes code readability. Its syntax allo… >>

Oct 26 | Topaz

Topaz is a pipeline for particle detection in cryo-electron microscopy images using convolutional neural networks trained from positive and… >>

Oct 22 | TranSPHIRE

a software package for fully automated processing of cryo-EM data sets during data acquisition. TranSPHIRE transfers data from the microsco… >>

Oct 22 | GROMACS

a versatile package that performs molecular dynamics of proteins, lipids and nucleic acids. >>

Oct 22 | CCP4

(Collaborative Computational Project, Number 4) a collection of programs and associated data and software libraries used for macromolecular… >>

Oct 21 | Coot

(Crystallographic Object-Oriented Toolkit) supports model building and real space refinement. This application interfaces with refmac, Phen… >>

Oct 21 | jq

is a lightweight and flexible command-line JSON processor. >>

Thanks to the National Science Foundation

With Partial Support from the National Science Foundation Research Coordination Network MCB #0639193 and NSF EAGER #1448069. Please cite SBGrid's eLife paper and follow our publication guidelines.

Latest news

SBGrid/Harvard Shield

SBGrid Weekly Webinar Series

Join us for our weekly webinar series --- Tuesdays at 12pm ET hear from developers and scientists about what's new in structural biology. Community members can connect via video, see …

Enzymatic action

Enzymatic action

Inside cells, DNA is coiled around histone proteins, making spools of nucleosomes. Cynthia Wolberger studies the molecular machines that unwrap the chromatin packing to transcribe or repair genes. The structures …

SBGrid/Harvard Shield

Position Postings for SBGrid Member Labs

Our position postings page advertises open positions for postdocs, students, faculty, and staff in SBGrid member laboratories and institutions. Please send brief descriptions to Michelle. Postings will remain online for …

Rules of motion

Rules of motion

Priyamvada Acharya studies how proteins on the surface of HIV move to invade cells and evade the immune system. For many years her research has been focused on the HIV-1 …

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