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  • The SBGrid Consortium provides structural biologists worldwide with access to the software they need to discover the shapes of the molecules of life. Read more in eLIFE and Acta Cryst.

  • SBCloud: AWS platform optimized for structural biology; pre-configured with scientific software for cryoEM & other techniques; user-friendly Open OnDemand interface; seamless Slurm job submission.

  • Capsules isolate the software runtime environment, encapsulating executables, libraries, and version-specific dependencies to provide conflict-free, zero-configuration access to structural biology software. Learn more.

  • The Project MAC display system, circa 1965. Read more about the history of molecular graphics software and UCSF Chimera in our SBGrid Tale featuring Bob Langridge and Tom Ferrin.

  • Train the Trainer Workshops: continuing education for structural biology mentors on cryoEM data processing workflows; resources PIs can take back to the laboratory. Funded by NIH R25 GM151273.

  • Personal Installation Manager: a structural biology app store; users install preferred applications/ versions on laptops or personal workstations, with graphical or CLI interfaces for Mac or Linux. More details.

SBGrid Consortium homepage

Recent Software Updates

Software updates
May 12 | Topaz

a pipeline for particle detection in cryo-electron microscopy images using convolutional neural networks trained from positive and unlabele… >>

May 12 | XDS

(X-ray Detector Software) a software tool for processing single-crystal monochromatic diffraction data recorded by the rotation method. >>

May 12 | ModelAngelo

an automatic atomic model building program for cryo-EM maps. >>

May 08 | BioEmu

is a model that samples from the approximated equilibrium distribution of structures for a protein monomer, given its amino acid sequence. >>

May 08 | ChimeraX

a tool of the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), fo… >>

May 07 | MemBrain-Seg

a tool for membrane segmentation in 3D for cryo-electron tomography (cryo-ET). >>

May 07 | cryoDRGN

a neural network based algorithm for heterogeneous cryo-EM reconstruction. In particular, the method models a continuous distribution over … >>

May 07 | MemBrain-Seg

a tool for membrane segmentation in 3D for cryo-electron tomography (cryo-ET). >>

May 07 | EMInfo

Deep learning framework for detecting the secondary structures of proteins and the region of nucleic acids in a cryo-EM map >>

May 06 | Follow_Relion_Gracefully

A complete dashboard for easy interaction with your cryo-EM data in Relion, now with full #teamtomo support! >>

Thanks to the National Science Foundation

With partial support from the NIH R25 Continuing Education for Structural Biology Mentors #GM151273, in collaboration with Co-PI Jamaine Davis; the NSF Research Coordination Network MCB #0639193, and NSF EAGER #1448069. Please cite SBGrid's eLife paper and follow our publication guidelines.

Latest news

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Latest upgrades from SBGrid, including latest software updates, new members and special events. Published montly by SBGrid.

SBGrid Webinar Series

Join us for our Software Webinar Series - Tuesdays at 12pm ET - to hear from software developers about what's new in structural biology. Community members connect via Zoom. Subscribe …

SBGrid/Harvard Shield

Capsules Technology

We have recently published a manuscript describing our Capsules technology used to deploy SBGrid and BioGrids software collections. Read more in Acta Cryst Section D, special 75th ICUR anniversary issue, …

Mind and Muscle

Mind and Muscle

From ancient Greece to modern day, people have often considered activities of the mind and muscle as fundamentally separate, even opposite, pursuits. Consider the contrasting stereotypes of a nerdy brainiac …

The Shapes of Energy

The Shapes of Energy

In Woods Hole, Mass., the Atlantic breeze mixes with the hum of microscopes and the chatter of biologists. There, in a summer neurobiology course, Luke Chao first became enthralled by …

Member publications

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