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  • The mobile element that conveys methicillin resistance to staph includes a gene that encodes for Cch. Learn more about Phoebe Rice's Chicago lab.

  • AlkD (grey) crystal structure bound to DNA containing 3-deaza-3-methyldeoxyadenosine (light green), from Brandt Eichman. Read the full story.

  • Jalview Developer Geoff Barton's desk with the JalviewAbacus (right) and displayed a dendrogram (tree) for the set of sequences shown in the alignment, using Jalview linked to Chimera. Read the full story here.

  • Project MAC display system, circa 1965,

    The Project MAC display system, circa 1965. Read more about the history of molecular graphics software and UCSF Chimera in our SBGrid Tale featuring Bob Langridge and Tom Ferrin.

  • You'll find SBGrid in ~350 structural biology labs located at over 100 different institutions in about 20 countries around the world. See full map and read more in eLIFE.

  • Daniel Panne's group, which relocated in 2018 to the University of Leicester, looks at the language of gene regulation and visualizes the catalytic core of p300. Read the full story.

  • Professor Catherine Drennan of MIT

    The SBGrid Consortium provides structural biologists worldwide with access to the software they need to discover the shapes of the molecules of life. Read more in eLIFE.

  • The AdipoR2 structure revealing the presence of a bound fatty acid at a zinc binding site, from Sebastien Granier's lab at the French National Institute of Health and Medical Research (INSERM), Institut de Génomique Fonctionnelle, Montpellier France. Read more.

  • Tom Rapoport's group at Harvard Medical School captured the crystal structure of the active translocon being pushed through the hourglass-shaped SecY protein-conducting channel. You can find out more about the science and learn some personal history in our Member Tale.

  • The first high-resolution (2.8 Å) X-ray crystal structure of the transcription initiation complex of Mycobacterium smegmatis, from the laboratory of Seth Darst at Rockefeller University.

    Image courtesy of E. Campbell.

  • In traditional X-ray crystallography, X-rays bombard 1 crystal 100s of times. This syringe, developed for a dynamic temperature experiment in James Fraser's lab at UCSF, shoots 1,000s of crystals into an X-ray-free electron laser beam, one at a time. Learn more.

    Image courtesy of Alexander Wolff.

Recent Software Updates

Mar 05 | GROMACS

a versatile package that performs molecular dynamics of proteins, lipids and nucleic acids. >>
Mar 04 | CryoAssess

an automatic pipeline for cryo-EM data preprocessing and assessment using a combination of deep learning and image analysis tools. >>
Mar 04 | RELION

(REgularised LIkelihood OptimisatioN) a stand-alone computer program for Maximum A Posteriori (MAP) refinement of (multiple) 3D reconstruct… >>
Mar 04 | Python

a general-purpose, interpreted, object oriented, high-level dynamic programming language that emphasizes code readability. Its syntax allo… >>
Feb 25 | Global Phasing Suite

combined installation of autoPROC, BUSTER, and SHARP available to Global Phasing consortium members. >>
Feb 25 | Schrodinger

a suite of tools for drug discovery. The Schrodinger suite runs on Linux and Mac workstations, but due to its size, it is not included in o… >>
Feb 25 | EMAN2

a scientific image processing suite with a particular focus on single particle reconstruction from cryoEM images. EMAN2 is a complete refac… >>
Thanks to the National Science Foundation

With Partial Support from the National Science Foundation Research Coordination Network MCB #0639193 and NSF EAGER #1448069. Please cite SBGrid's eLife paper and follow our publication guidelines.

Latest news

SBGrid Weekly Webinar Series

Join us for our weekly webinar series --- Tuesdays at 12pm ET hear from developers and scientists about what's new in structural biology. Community members can connect via Zoom and …

Right place, right time

Right place, right time

As a kid, Ernesto Fuentes lived in Brazil just long enough to stock up on the soccer skills he now shares with his kids. His affinity for structural biology may …

SBGrid/Harvard Shield

Position Postings for SBGrid Member Labs

Our position postings page advertises open positions for postdocs, students, faculty, and staff in SBGrid member laboratories and institutions. Please send brief descriptions to Michelle. Postings will remain online for …

Shape-shifting secrets of membranes

Shape-shifting secrets of membranes

The story of how a viral protein meets a cell membrane has become a compelling narrative during the COVID-19 pandemic. James Hurley at University of California, Berkeley, understands the appeal …

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