Member Publications
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24 Member Publications for September
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Bicistronic CD19/CD22 CAR T-Cell Therapy in Pediatric B-Cell Acute Lymphoblastic Leukemia: A Nonrandomized Clinical Trial.
- JAMA Oncol - published September 3, 2026
- Wan X, Tang Y, Cai J, Song L, Wang T, Li W, Yang L, Wang X, Luo C, Zhu H, An K, Su M, Zhang J, Yang J, Shi W, Fei C, Shen W, Jia R, Yang X, Tang J, Wu J, Gu J, Mo J, Huang J, Li Y, Zhou G, Ding L, Liang J, Wang J, Zhou Z, Wang X, Cao Q, Zhang J, Ren H, Qian J, Xiao P, He H, Jiang H, Hu S, Wang N, Zhu Y, Tang J, Gu L, Yang J, Cheng C, Chen J, Kuai W, Lu X, Shao J, Xie Z, Lu J, Leung W, Li B, Pui CH
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2''F-NAD(+) is a broad-spectrum RNA 2'-phosphotransferase (Tpt1) poison that traps the enzyme on its abortive RNA-2'-phospho-(2''F-ADP-ribose) reaction intermediate.
- RNA - published September 3, 2026
- Kasprzyk R, Ghosh S, Shuman S
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MOSAIC: A flexible, software-agnostic workflow for montage cryo-ET.
- Structure - published September 3, 2026
- Jensen J, Mendonça L
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In extracto cryo-EM reveals eEF2 as a major hibernation factor on 60S and 80S particles.
- Elife - published September 3, 2026
- Seraj Z, Zottig X, Huang C, Loveland AB, Diggs S, Sholi E, Grigorieff N, Korostelev AA
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Early-life colonization with Clostridioides difficile remodels the developing gut.
- Science - published September 3, 2026
- Semon A, Manzer HS, Keenan O, Zhou TH, Tiffany C, She Q, Knight M, Weiss AS, Donohoe K, Morrow BT, Glover RC, Kovalik ME, Tanes C, Bittinger K, Zemel BS, Wu GD, Silverman MA, Gerber JS, Cano Rodríguez R, Lacy DB, Karakasheva TA, Alameh MG, Weissman D, Schultz-Cherry SL, Rosch JW, Planet PJ, Moustafa AM, Furth EE, Abt MC, Kelsen JR, Conrad MA, Hamilton KE, Zackular JP
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Creating bottom-up RNA transfer vehicles from synthetic protein assemblies.
- Nature - published September 2, 2026
- Schuhmacher MK, Gruber C, Lang CMR, Ruijpers RMW, Mazneykova L, Beinsteiner B, Krus A, Tremmel B, Reinhardt F, Kadletz K, Ma Z, Casalta L, Cambra Bort JM, Otify DY, Balken I, Hetzel L, Merl-Pham J, Dorn T, Luchner M, Bauersachs L, Ganea K, Wieser N, Emrich A, Yağmur E, Rager K, Sagindykova G, Armbrust N, Geilenkeuser J, Westmeyer GG, Becirovic E, Biel M, Istvanffy R, Vogt Weisenhorn DM, Truong DJ, Theis FJ, Ebert G, Moretti A, Ertürk A, Bähr A, Kupatt C, Jasnin M, Klymiuk N, Giesert F, Wurst W
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HIV-1 antibody-mediated neutralization via a dual-glycan clamp.
- Cell Rep - published September 2, 2026
- Gorman J, Ballard RB, Nazzari AF, O'Dell S, Bylund T, Rawi R, Du R, Nguyen R, Ambrozak D, Zhang B, Du H, Doria-Rose NA, Connors M, Mascola JR, Zhou T, Kwong PD, Roederer M, Mason RD
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Structure and operating principles of a monkeypox virus replisome.
- Nature - published September 2, 2026
- Yu Z, Sathyanarayana P, Tan JMJ, Hu S, Fan X, Gao A, Kranzusch PJ, Loparo JJ, Abraham J
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Functional chimeric mRNAs encode proteins in mammalian immunity.
- Nature - published September 2, 2026
- Venezia O, Kane H, Du G, Coughlan HD, Johanson TM, Wang H, Tilstam P, Kazer SW, Gunner G, Hoagland DA, Basavappa MG, Ravichandran K, Ada E, Zhakyp A, Kumar S, Duizer C, Searle O, Provido CG, Joannas L, Yang S, Healy LB, Wang Q, Capocchi J, Dhillon BS, Slavoff S, Shan L, Henao-Mejia J, Franklin RA, Chiu IM, Ordovas-Montanes J, Jeffrey KL, Lieberman J, Allan RS, Kagan JC, Wu H, Jackson R
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Multifunctional antibody responses from a primate Shigella outbreak inform vaccine design.
- Sci Transl Med - published September 2, 2026
- Gallant RM, Savarino P, Pulido S, Gilman MSA, Lu T, Hayes J, Xerri NL, Williams T, Ochoa MA, Dietz Z, Peterson E, Scott T, Hartmann F, Baker SG, Kaminski RW, Sok D, Kruse AC, Picking W, Capuano SV, Schmidt HR
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Multimodal analysis of CD38 in T-cell Acute Lymphoblastic Leukemia Identifies Combinatorial Therapeutic Strategies.
- Blood - published September 2, 2026
- Shraim R, Shi G, Li Y, Xu J, Fuller T, Martinez Z, McGrath L, Aplenc R, Cairo MS, Glisovic-Aplenc T, Gill SI, Grupp SA, Hermiston ML, Hogarty MD, Horton T, Hughes AD, June CH, Mullighan CG, Newman H, Pölönen P, Stadtmauer E, Tan K, Tasian SK, Teachey L, Teachey HE, Turn CS, Wang'ondu RW, Wood B, Wertheim G, Teachey DT, Yang JJ, Diorio C
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Comparative evaluation of screening approaches for antiviral monoclonal antibody combinations.
- J Virol - published September 2, 2026
- McClave MK, Marzi SK, Heldwein EE
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Cryo-Electron Tomography Reveals Nanoscale Thick Filament Disorganization in MYH7 P710R Hypertrophic Cardiomyopathy Cardiomyocytes.
- ACS Nano - published September 1, 2026
- Zaoralová M, Yoniles J, Giri P, Held RG, Vander Roest A, Dahlberg PD, Bernstein D, Dunn AR, Engel L
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Structural and biophysical characterization of Mycobacterium tuberculosis DciA reveals functional convergence in DnaB helicase recognition.
- Protein Sci - published September 1, 2026
- Mazzoletti D, Garavaglia A, Fisher H, Gao N, Morrone C, Olinares PDB, Chait BT, Jeruzalmi D, Miggiano R
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Towards routine accurate electron-density studies of biological macromolecules.
- Acta Crystallogr D Struct Biol - published September 1, 2026
- Paknia E, Flensburg C, Chodkiewicz ML, Fogh RH, Keller P, Vonrhein C, Schulze-Briese C, Dominiak PM, Bourenkov G, Bricogne G, Chari A
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Reexamining the activation mechanisms of adhesion G protein-coupled receptors.
- Sci Signal - published September 1, 2026
- Araç D, Kordon SP
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Identification of a key water molecule involved in the macrophage migration inhibitory factor-catalyzed tautomerization of para-hydroxyphenylpyruvate using neutron crystallography.
- Protein Sci - published September 1, 2026
- Schröder GC, Crichlow GV, Jablonowski E, Pantouris G, Nix J, Chayen N, Meilleur F, Lolis EJ
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Conformational asymmetry of human immunodeficiency virus-1 protease flaps increases along the darunavir drug resistance pathway.
- Protein Sci - published September 1, 2026
- Guerrero M, Zadorozhnyi R, Lin G, Quinn CM, Calero G, Kurt-Yilmaz N, Schiffer CA, Polenova T, Gronenborn AM, Ishima R
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Structural insights into fosfomycin efflux by a streptococcal ABC transporter.
- Proc Natl Acad Sci U S A - published September 1, 2026
- Taguchi A, Fujita J, Tanabe M, Takaya D, Harada K, Moriya T, Fukuzawa K, Namba K, Nishino K
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Engineering antigenic breadth against SARS-CoV-2 by pairing divergent RBDs within a single mRNA immunogen.
- Proc Natl Acad Sci U S A - published September 1, 2026
- Montgomerie I, McKenzie RE, Palmer OR, Mason NC, Kuang J, Pankhurst TE, Draper SL, von Daake S, Eccles DA, Bird TW, Martin AL, Green I, White L, Robinson Z, Marshall A, Minnell JJ, Small SJ, Hermans IF, Painter GF, Ussher JE, Quiñones-Mateu ME, Patrick WM, Comoletti D, Connor LM
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Structural basis of GSDME pore formation and its regulation by S-palmitoylation.
- Proc Natl Acad Sci U S A - published September 1, 2026
- Du G, Ehrmann JF, Lieberman J, Wu H
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Avoiding pitfalls when modelling ligands in macromolecular crystallography.
- Acta Crystallogr D Struct Biol - published September 1, 2026
- Smart OS, Sharff A, Flensburg C, Vonrhein C, Bricogne G
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A novel corneal epithelial cell culture assay for assessing topical antivirals against herpes simplex virus keratitis.
- Biochem Biophys Rep - published September 1, 2026
- Kuniyoshi H, Numata Y, Sasano M, Hayashi H, Fuse N, Sarafianos SG, Kodama EN
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Multiobjective learning and design of bacteriophage specificity.
- Cell Syst - published September 1, 2026
- Novy N, Huss P, Evert S, Romero PA, Raman S