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31 Member Publications for January

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Molecular Dissection of the Primase and Polymerase Activities of Deep-Sea Phage NrS-1 Primase-Polymerase.
1. Front Microbiol - published January 3, 2022
2. Huang F, Lu X, Yu C, Sliz P, Wang L, Zhu B
Protection of the prodomain α1-helix correlates with latency in the transforming growth factor-β family.
1. J Mol Biol - published January 3, 2022
2. Le VQ, Iacob RE, Zhao B, Su Y, Tian Y, Toohey C, Engen JR, Springer TA
The Pseudomonas aeruginosa homeostasis enzyme AlgL clears the periplasmic space of accumulated alginate during polymer biosynthesis.
1. J Biol Chem - published January 3, 2022
2. Gheorghita AA, Wolfram F, Whitfield GB, Jacobs HM, Pfoh R, Wong SSY, Guitor AK, Goodyear MC, Berezuk AM, Khursigara CM, Parsek MR, Howell PL
Advances toward structure-based drug discovery for inflammasome targets.
1. J Exp Med - published January 3, 2022
2. Wang L, Crackower MA, Wu H
A stem-loop RNA RIG-I agonist protects against acute and chronic SARS-CoV-2 infection in mice.
1. J Exp Med - published January 3, 2022
2. Mao T, Israelow B, Lucas C, Vogels CBF, Gomez-Calvo ML, Fedorova O, Breban MI, Menasche BL, Dong H, Linehan M, Yale SARS-CoV-2 Genome Surveillance Initiative., Wilen CB, Landry ML, Grubaugh ND, Pyle AM, Iwasaki A
Selective binding of small molecules to Vibrio cholerae DsbA offers a starting point for the design of novel antibacterials.
1. ChemMedChem - published January 2, 2022
2. Wang G, Mohanty B, Williams ML, Doak BC, Dhouib R, Totsika M, McMahon R, Sharma G, Zheng D, Bentley MR, Chin YK, Horne J, Chalmers DK, Heras B, Scanlon MJ
Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease.
1. Nat Commun - published January 1, 2022
2. Yang Y, Tapias V, Acosta D, Xu H, Chen H, Bhawal R, Anderson ET, Ivanova E, Lin H, Sagdullaev BT, Chen J, Klein WL, Viola KL, Gandy S, Haroutunian V, Beal MF, Eliezer D, Zhang S, Gibson GE
Defensin-lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics.
1. Biochem Soc Trans - published January 1, 2022
2. Hein MJA, Kvansakul M, Lay FT, Phan TK, Hulett MD
Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance.
1. Elife - published January 1, 2022
2. Tsai K, Stojković V, Noda-Garcia L, Young ID, Myasnikov AG, Kleinman J, Palla A, Floor SN, Frost A, Fraser JS, Tawfik DS, Fujimori DG
Conceptual Exchanges for Understanding Free-Living and Host-Associated Microbiomes.
1. mSystems - published January 1, 2022
2. Pfister CA, Light SH, Bohannan B, Schmidt T, Martiny A, Hynson NA, Devkota S, David L, Whiteson K
Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses.
1. Cell Chem Biol - published January 1, 2022
2. Napolitano V, Dabrowska A, Schorpp K, Mourão A, Barreto-Duran E, Benedyk M, Botwina P, Brandner S, Bostock M, Chykunova Y, Czarna A, Dubin G, Fröhlich T, Hölscher M, Jedrysik M, Matsuda A, Owczarek K, Pachota M, Plettenburg O, Potempa J, Rothenaigner I, Schlauderer F, Slysz K, Szczepanski A, Greve-Isdahl Mohn K, Blomberg B, Sattler M, Hadian K, Popowicz GM, Pyrc K
Publisher Correction: Self-association of MreC as a regulatory signal in bacterial cell wall elongation.
1. Nat Commun - published January 1, 2022
2. Martins A, Contreras-Martel C, Janet-Maitre M, Miyachiro MM, Estrozi LF, Trindade DM, Malospirito CC, Rodrigues-Costa F, Imbert L, Job V, Schoehn G, Attrée I, Dessen A
Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival.
1. Blood Cancer Discov - published January 1, 2022
2. Li M, Teater MR, Hong JY, Park NR, Duy C, Shen H, Wang L, Chen Z, Cerchietti L, Davidson SM, Lin H, Melnick AM
Design principles for site-selective hydroxylation by a Rieske oxygenase.
1. Nat Commun - published January 1, 2022
2. Liu J, Tian J, Perry C, Lukowski AL, Doukov TI, Narayan ARH, Bridwell-Rabb J
Bacterial gasdermins reveal an ancient mechanism of cell death.
1. Science - published January 1, 2022
2. Johnson AG, Wein T, Mayer ML, Duncan-Lowey B, Yirmiya E, Oppenheimer-Shaanan Y, Amitai G, Sorek R, Kranzusch PJ
First prediction of sequence-specific recognition of double-helix nucleic acids by proteins.
1. Nat Rev Mol Cell Biol - published January 1, 2022
2. Egli M, Zhang S
Connexin 43 confers chemoresistance through activating PI3K.
1. Oncogenesis - published January 1, 2022
2. Pridham KJ, Shah F, Hutchings KR, Sheng KL, Guo S, Liu M, Kanabur P, Lamouille S, Lewis G, Morales M, Jourdan J, Grek CL, Ghatnekar GG, Varghese R, Kelly DF, Gourdie RG, Sheng Z
Simplified quality assessment for small-molecule ligands in the Protein Data Bank.
1. Structure - published January 1, 2022
2. Shao C, Westbrook JD, Lu C, Bhikadiya C, Peisach E, Young JY, Duarte JM, Lowe R, Wang S, Rose Y, Feng Z, Burley SK
Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats.
1. Elife - published January 1, 2022
2. Kucharska I, Hossain L, Ivanochko D, Yang Q, Rubinstein JL, Pomès R, Julien JP
The multiple molecular dimensions of long noncoding RNAs that regulate gene expression and tumorigenesis.
1. Curr Opin Oncol - published January 1, 2022
2. Marcia M
Time management for STEMM students during the continuing pandemic.
1. Trends Biochem Sci - published January 1, 2022
2. Murray SA, Davis J, Shuler HD, Spencer EC, Hinton A Jr
Innovative vaccine approaches-a Keystone Symposia report.
1. Ann N Y Acad Sci - published January 1, 2022
2. Cable J, Rappuoli R, Klemm EJ, Kang G, Mutreja A, Wright GJ, Pizza M, Castro SA, Hoffmann JP, Alter G, Carfi A, Pollard AJ, Krammer F, Gupta RK, Wagner CE, Machado V, Modjarrad K, Corey L, B Gilbert P, Dougan G, Lurie N, Bjorkman PJ, Chiu C, Nemes E, Gordon SB, Steer AC, Rudel T, Blish CA, Sandberg JT, Brennan K, Klugman KP, Stuart LM, Madhi SA, Karp CL
Nipah Virus V Protein Binding Alters MDA5 Helicase Folding Dynamics.
1. ACS Infect Dis - published January 1, 2022
2. Wagner ND, Liu H, Rohrs HW, Amarasinghe GK, Gross ML, Leung DW
Aminopyridine analogs selectively target metastatic pancreatic cancer.
1. Oncogene - published January 1, 2022
2. Smalling RV, Bechard ME, Duryea J, Kingsley PJ, Roberts ER, Marnett LJ, Bilbao D, Stauffer SR, McDonald OG
Author Correction: Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc.
1. Nat Commun - published January 1, 2022
2. Matsuda S, Schaefer JV, Mii Y, Hori Y, Bieli D, Taira M, Plückthun A, Affolter M
The crystal structure of DynF from the dynemicin-biosynthesis pathway of Micromonospora chersina.
1. Acta Crystallogr F Struct Biol Commun - published January 1, 2022
2. Kosgei AJ, Miller MD, Bhardwaj M, Xu W, Thorson JS, Van Lanen SG, Phillips GN Jr
RNA in biological condensates.
1. RNA - published January 1, 2022
2. Cech TR
Crystal structures of FolM alternative dihydrofolate reductase 1 from Brucella suis and Brucella canis.
1. Acta Crystallogr F Struct Biol Commun - published January 1, 2022
2. Porter I, Neal T, Walker Z, Hayes D, Fowler K, Billups N, Rhoades A, Smith C, Smith K, Staker BL, Dranow DM, Mayclin SJ, Subramanian S, Edwards TE, Myler PJ, Asojo OA
Crystal structure of a putative short-chain dehydrogenase/reductase from Paraburkholderia xenovorans.
1. Acta Crystallogr F Struct Biol Commun - published January 1, 2022
2. Davidson J, Nicholas K, Young J, Conrady DG, Mayclin S, Subramanian S, Staker BL, Myler PJ, Asojo OA
Structural transitions in the GTP cap visualized by cryo-electron microscopy of catalytically inactive microtubules.
1. Proc Natl Acad Sci U S A - published January 1, 2022
2. LaFrance BJ, Roostalu J, Henkin G, Greber BJ, Zhang R, Normanno D, McCollum CO, Surrey T, Nogales E
Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family.
1. Elife - published January 1, 2022
2. Ramanadane K, Straub MS, Dutzler R, Manatschal C