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96 Member Publications for May

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Characterization of a human monoclonal antibody generated from a B-cell specific for a prefusion-stabilized spike protein of Middle East respiratory syndrome coronavirus.
1. PLoS One - published May 9, 2020
2. Choi JH, Woo HM, Lee TY, Lee SY, Shim SM, Park WJ, Yang JS, Kim JA, Yun MR, Kim DW, Kim SS, Zhang Y, Shi W, Wang L, Graham BS, Mascola JR, Wang N, McLellan JS, Lee JY, Lee H
Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein.
1. Nat Commun - published May 8, 2020
2. Piai A, Fu Q, Cai Y, Ghantous F, Xiao T, Shaik MM, Peng H, Rits-Volloch S, Chen W, Seaman MS, Chen B, Chou JJ
ABCG2 transports anticancer drugs via a closed-to-open switch.
1. Nat Commun - published May 8, 2020
2. Orlando BJ, Liao M
Diversity in kinetics correlated with structure in nano body-stabilized LacY.
1. PLoS One - published May 8, 2020
2. Kumar H, Finer-Moore J, Smirnova I, Kasho V, Pardon E, Steyaert J, Kaback HR, Stroud RM
Selective Janus Kinase 2 (JAK2) Pseudokinase Ligands with a Diaminotriazole Core.
1. J Med Chem - published May 8, 2020
2. Liosi ME, Krimmer SG, Newton AS, Dawson TK, Puleo DE, Cutrona KJ, Suzuki Y, Schlessinger J, Jorgensen WL
Lactoferrin-hexon interactions mediate CAR-independent adenovirus infection of human respiratory cells.
1. J Virol - published May 6, 2020
2. Persson BD, Lenman A, Frängsmyr L, Schmidt M, Ahlm C, Plückthun A, Jenssen H, Arnberg N
Yeast pericentrin/Spc110 contains multiple domains required for tethering the gamma tubulin complex to the centrosome.
1. Mol Biol Cell - published May 6, 2020
2. Alonso A, Fabritius A, Ozzello C, Andreas M, Klenchin D, Rayment I, Winey M
Nanoadhesive layer to prevent protein absorption in a poly(dimethylsiloxane) microfluidic device.
1. Biotechniques - published May 6, 2020
2. You JB, Lee B, Choi Y, Lee CS, Peter M, Im SG, Lee SS
Cryo-EM structures and functional properties of CALHM channels of the human placenta.
1. Elife - published May 6, 2020
2. Drożdżyk K, Sawicka M, Bahamonde-Santos MI, Jonas Z, Deneka D, Albrecht C, Dutzler R
Methylation deficiency disrupts biological rhythms from bacteria to humans.
1. Commun Biol - published May 6, 2020
2. Fustin JM, Ye S, Rakers C, Kaneko K, Fukumoto K, Yamano M, Versteven M, Grünewald E, Cargill SJ, Tamai TK, Xu Y, Jabbur ML, Kojima R, Lamberti ML, Yoshioka-Kobayashi K, Whitmore D, Tammam S, Howell PL, Kageyama R, Matsuo T, Stanewsky R, Golombek DA, Johnson CH, Kakeya H, van Ooijen G, Okamura H
Finally on Track: Interactions of Off-Track with Plex-Sema Pathway and Glycosaminoglycans.
1. Structure - published May 5, 2020
2. Cheng S, Özkan E
Elevator-type mechanisms of membrane transport.
1. Biochem Soc Trans - published May 5, 2020
2. Garaeva AA, Slotboom DJ
Conserved Outer Tegument Component UL11 from Herpes Simplex Virus 1 Is an Intrinsically Disordered, RNA-Binding Protein.
1. mBio - published May 5, 2020
2. Metrick CM, Koenigsberg AL, Heldwein EE
Trib1 regulates T cell differentiation during chronic infection by restraining the effector program.
1. J Exp Med - published May 4, 2020
2. Rome KS, Stein SJ, Kurachi M, Petrovic J, Schwartz GW, Mack EA, Uljon S, Wu WW, DeHart AG, McClory SE, Xu L, Gimotty PA, Blacklow SC, Faryabi RB, Wherry EJ, Jordan MS, Pear WS
Golgi-associated BICD adaptors couple ER membrane penetration and disassembly of a viral cargo.
1. J Cell Biol - published May 4, 2020
2. Spriggs CC, Badieyan S, Verhey KJ, Cianfrocco MA, Tsai B
Cryo-EM reconstruction of a VPS13 fragment reveals a long groove to channel lipids between membranes.
1. J Cell Biol - published May 4, 2020
2. Li P, Lees JA, Lusk CP, Reinisch KM
A firehose for phospholipids.
1. J Cell Biol - published May 4, 2020
2. Prinz WA, Hurley JH
Human monoclonal antibodies against Ross River virus target epitopes within the E2 protein and protect against disease.
1. PLoS Pathog - published May 4, 2020
2. Powell LA, Fox JM, Kose N, Kim AS, Majedi M, Bombardi R, Carnahan RH, Slaughter JC, Morrison TE, Diamond MS, Crowe JE Jr
Transferrin binding protein B and Transferrin binding protein A 2 expand the transferrin recognition range of Histophilus somni.
1. J Bacteriol - published May 4, 2020
2. Pogoutse AK, Moraes TF
Site-specific glycan analysis of the SARS-CoV-2 spike.
1. Science - published May 4, 2020
2. Watanabe Y, Allen JD, Wrapp D, McLellan JS, Crispin M
FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation.
1. Nat Immunol - published May 4, 2020
2. Hu JJ, Liu X, Xia S, Zhang Z, Zhang Y, Zhao J, Ruan J, Luo X, Lou X, Bai Y, Wang J, Hollingsworth LR, Magupalli VG, Zhao L, Luo HR, Kim J, Lieberman J, Wu H
Discovery of Ubonodin, an Antimicrobial Lasso Peptide Active against Members of the Burkholderia cepacia Complex.
1. Chembiochem - published May 4, 2020
2. Cheung-Lee WL, Parry ME, Zong C, Cartagena AJ, Darst SA, Connell ND, Russo R, Link AJ
The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells.
1. Mol Pharmacol - published May 3, 2020
2. Maximov PY, Abderrahman B, Hawsawi YM, Chen Y, Foulds CE, Jain A, Malovannaya A, Fan P, Curpan RF, Han R, Fanning SW, Broom BM, Quintana Rincon DM, Greenland JA, Greene GL, Jordan VC
The large family of PC4-like domains - similar folds and functions throughout all kingdoms of life.
1. RNA Biol - published May 3, 2020
2. Janowski R, Niessing D
Pandemic Preparedness: Developing Vaccines and Therapeutic Antibodies For COVID-19.
1. Cell - published May 2, 2020
2. Sempowski GD, Saunders KO, Acharya P, Wiehe KJ, Haynes BF
Competitive tight-binding inhibition of VKORC1 underlies warfarin dosage variation and antidotal efficacy.
1. Blood Adv - published May 2, 2020
2. Li S, Liu S, Liu XR, Zhang MM, Li W
Professional development outcomes associated with interdisciplinary research: An integrative review.
1. Nurs Outlook - published May 2, 2020
2. Bruzzese JM, Usseglio J, Goldberg J, Begg MD, Larson EL
Conformational dynamics from ambiguous zinc coordination in the RanBP2-type zinc finger of RBM5.
1. J Mol Biol - published May 2, 2020
2. Soni K, Martínez-Lumbreras S, Sattler M
Immunogenicity of a DNA vaccine candidate for COVID-19.
1. Nat Commun - published May 2, 2020
2. Smith TRF, Patel A, Ramos S, Elwood D, Zhu X, Yan J, Gary EN, Walker SN, Schultheis K, Purwar M, Xu Z, Walters J, Bhojnagarwala P, Yang M, Chokkalingam N, Pezzoli P, Parzych E, Reuschel EL, Doan A, Tursi N, Vasquez M, Choi J, Tello-Ruiz E, Maricic I, Bah MA, Wu Y, Amante D, Park DH, Dia Y, Ali AR, Zaidi FI, Generotti A, Kim KY, Herring TA, Reeder S, Andrade VM, Buttigieg K, Zhao G, Wu JM, Li D, Bao L, Liu J, Deng W, Qin C, Brown AS, Khoshnejad M, Wang N, Chu J, Wrapp D, McLellan JS, Muthumani K, Wang B, Carroll MW, Kim JJ, Boyer J, Kulp DW, Humeau LMPF, Weiner DB, Broderick KE
Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities.
1. Nat Commun - published May 2, 2020
2. Nichols CA, Gibson WJ, Brown MS, Kosmicki JA, Busanovich JP, Wei H, Urbanski LM, Curimjee N, Berger AC, Gao GF, Cherniack AD, Dhe-Paganon S, Paolella BR, Beroukhim R
DNA vaccine protection against SARS-CoV-2 in rhesus macaques.
1. Science - published May 2, 2020
2. Yu J, Tostanoski LH, Peter L, Mercado NB, McMahan K, Mahrokhian SH, Nkolola JP, Liu J, Li Z, Chandrashekar A, Martinez DR, Loos C, Atyeo C, Fischinger S, Burke JS, Slein MD, Chen Y, Zuiani A, N Lelis FJ, Travers M, Habibi S, Pessaint L, Van Ry A, Blade K, Brown R, Cook A, Finneyfrock B, Dodson A, Teow E, Velasco J, Zahn R, Wegmann F, Bondzie EA, Dagotto G, Gebre MS, He X, Jacob-Dolan C, Kirilova M, Kordana N, Lin Z, Maxfield LF, Nampanya F, Nityanandam R, Ventura JD, Wan H, Cai Y, Chen B, Schmidt AG, Wesemann DR, Baric RS, Alter G, Andersen H, Lewis MG, Barouch DH
SARS-CoV-2 infection protects against rechallenge in rhesus macaques.
1. Science - published May 2, 2020
2. Chandrashekar A, Liu J, Martinot AJ, McMahan K, Mercado NB, Peter L, Tostanoski LH, Yu J, Maliga Z, Nekorchuk M, Busman-Sahay K, Terry M, Wrijil LM, Ducat S, Martinez DR, Atyeo C, Fischinger S, Burke JS, Slein MD, Pessaint L, Van Ry A, Greenhouse J, Taylor T, Blade K, Cook A, Finneyfrock B, Brown R, Teow E, Velasco J, Zahn R, Wegmann F, Abbink P, Bondzie EA, Dagotto G, Gebre MS, He X, Jacob-Dolan C, Kordana N, Li Z, Lifton MA, Mahrokhian SH, Maxfield LF, Nityanandam R, Nkolola JP, Schmidt AG, Miller AD, Baric RS, Alter G, Sorger PK, Estes JD, Andersen H, Lewis MG, Barouch DH
A bacterial biosynthetic pathway for methylated furan fatty acids.
1. J Biol Chem - published May 2, 2020
2. Lemke RAS, Olson SM, Morse K, Karlen SD, Higbee A, Beebe ET, Ralph J, Coon JJ, Fox BG, Donohue TJ
Ion transport and regulation in a synaptic vesicle glutamate transporter.
1. Science - published May 2, 2020
2. Li F, Eriksen J, Finer-Moore J, Chang R, Nguyen P, Bowen A, Myasnikov A, Yu Z, Bulkley D, Cheng Y, Edwards RH, Stroud RM
Fragment screening targeting Ebola virus nucleoprotein C-terminal domain identifies lead candidates.
1. Antiviral Res - published May 2, 2020
2. Aceti DJ, Ahmed H, Westler WM, Wu C, Dashti H, Tonelli M, Eghbalnia H, Amarasinghe GK, Markley JL
Optical Gap Biomarker in Cone-Dominant Retinal Dystrophy.
1. Am J Ophthalmol - published May 2, 2020
2. Oh JK, Ryu J, Lima de Carvalho JR Jr, Levi SR, Lee W, Tsamis E, Greenstein VC, Mahajan VB, Allikmets R, Tsang SH
Characterization of Warfarin Inhibition Kinetics Requires Stabilization of Intramembrane Vitamin K Epoxide Reductases.
1. J Mol Biol - published May 2, 2020
2. Li S, Liu S, Yang Y, Li W
Visualizing the functional 3D shape and topography of long noncoding RNAs by single-particle atomic force microscopy and in-solution hydrodynamic techniques.
1. Nat Protoc - published May 2, 2020
2. Uroda T, Chillón I, Annibale P, Teulon JM, Pessey O, Karuppasamy M, Pellequer JL, Marcia M
Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
1. Nat Med - published May 2, 2020
2. Murugan R, Scally SW, Costa G, Mustafa G, Thai E, Decker T, Bosch A, Prieto K, Levashina EA, Julien JP, Wardemann H
Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures.
1. Nat Commun - published May 2, 2020
2. Wang M, Li R, Shu B, Jing X, Ye HQ, Gong P
Hydrocarbon-Stitched Peptide Agonists of Glucagon-Like Peptide-1 Receptor.
1. ACS Chem Biol - published May 2, 2020
2. Bird GH, Fu A, Escudero S, Godes M, Opoku-Nsiah K, Wales TE, Cameron MD, Engen JR, Danial NN, Walensky LD
Molecular Insight into TdfH-Mediated Zinc Piracy from Human Calprotectin by Neisseria gonorrhoeae.
1. mBio - published May 2, 2020
2. Kammerman MT, Bera A, Wu R, Harrison SA, Maxwell CN, Lundquist K, Noinaj N, Chazin WJ, Cornelissen CN
Characterization of the kinetic cycle of an ABC transporter by single-molecule and cryo-EM analyses.
1. Elife - published May 2, 2020
2. Wang L, Johnson ZL, Wasserman MR, Levring J, Chen J, Liu S
The architecture of EMC reveals a path for membrane protein insertion.
1. Elife - published May 2, 2020
2. O'Donnell JP, Phillips BP, Yagita Y, Juszkiewicz S, Wagner A, Malinverni D, Keenan RJ, Miller EA, Hegde RS
The HIV-1 Env gp120 Inner Domain Shapes the Phe43 Cavity and the CD4 Binding Site.
1. mBio - published May 2, 2020
2. Prévost J, Tolbert WD, Medjahed H, Sherburn RT, Madani N, Zoubchenok D, Gendron-Lepage G, Gaffney AE, Grenier MC, Kirk S, Vergara N, Han C, Mann BT, Chénine AL, Ahmed A, Chaiken I, Kirchhoff F, Hahn BH, Haim H, Abrams CF, Smith AB 3rd, Sodroski J, Pazgier M, Finzi A
Vulnerabilities in coronavirus glycan shields despite extensive glycosylation.
1. Nat Commun - published May 2, 2020
2. Watanabe Y, Berndsen ZT, Raghwani J, Seabright GE, Allen JD, Pybus OG, McLellan JS, Wilson IA, Bowden TA, Ward AB, Crispin M
Electromechanical coupling in the hyperpolarization-activated K+ channel KAT1.
1. Nature - published May 2, 2020
2. Clark MD, Contreras GF, Shen R, Perozo E
USP37 promotes deubiquitination of HIF2α in kidney cancer.
1. Proc Natl Acad Sci U S A - published May 2, 2020
2. Hong K, Hu L, Liu X, Simon JM, Ptacek TS, Zheng X, Liao C, Baldwin AS, Zhang Q
Structure and mechanism of a unique diiron center in mammalian stearoyl-CoA desaturase.
1. J Mol Biol - published May 2, 2020
2. Shen J, Wu G, Tsai AL, Zhou M
A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity.
1. Science - published May 2, 2020
2. Meeske AJ, Jia N, Cassel AK, Kozlova A, Liao J, Wiedmann M, Patel DJ, Marraffini LA
Anisotropic ESCRT-III architecture governs helical membrane tube formation.
1. Nat Commun - published May 2, 2020
2. Moser von Filseck J, Barberi L, Talledge N, Johnson IE, Frost A, Lenz M, Roux A
Karyopherins and condensates.
1. Curr Opin Cell Biol - published May 2, 2020
2. Springhower CE, Rosen MK, Chook YM
Structure-Guided Optimization of Inhibitors of Acetyltransferase Eis from Mycobacterium tuberculosis.
1. ACS Chem Biol - published May 1, 2020
2. Punetha A, Ngo HX, Holbrook SYL, Green KD, Willby MJ, Bonnett SA, Krieger K, Dennis EK, Posey JE, Parish T, Tsodikov OV, Garneau-Tsodikova S
The Conformational States of the HIV-1 Envelope Glycoproteins.
1. Trends Microbiol - published May 1, 2020
2. Wang Q, Finzi A, Sodroski J
Author Correction: Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer.
1. Nat Commun - published May 1, 2020
2. Färkkilä A, Gulhan DC, Casado J, Jacobson CA, Nguyen H, Kochupurakkal B, Maliga Z, Yapp C, Chen YA, Schapiro D, Zhou Y, Graham JR, Dezube BJ, Munster P, Santagata S, Garcia E, Rodig S, Lako A, Chowdhury D, Shapiro GI, Matulonis UA, Park PJ, Hautaniemi S, Sorger PK, Swisher EM, D'Andrea AD, Konstantinopoulos PA
Integrated Structural Modeling of Full-Length LRH-1 Reveals Inter-domain Interactions Contribute to Receptor Structure and Function.
1. Structure - published May 1, 2020
2. Seacrist CD, Kuenze G, Hoffmann RM, Moeller BE, Burke JE, Meiler J, Blind RD
Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme.
1. Nature - published May 1, 2020
2. Sui X, Wang K, Gluchowski NL, Elliott SD, Liao M, Walther TC, Farese RV Jr
Structure-Guided Identification of DNMT3B Inhibitors.
1. ACS Med Chem Lett - published May 1, 2020
2. Newton AS, Faver JC, Micevic G, Muthusamy V, Kudalkar SN, Bertoletti N, Anderson KS, Bosenberg MW, Jorgensen WL
DIP/Dpr interactions and the evolutionary design of specificity in protein families.
1. Nat Commun - published May 1, 2020
2. Sergeeva AP, Katsamba PS, Cosmanescu F, Brewer JJ, Ahlsen G, Mannepalli S, Shapiro L, Honig B
A Primase-Induced Conformational Switch Controls the Stability of the Bacterial Replisome.
1. Mol Cell - published May 1, 2020
2. Monachino E, Jergic S, Lewis JS, Xu ZQ, Lo ATY, O'Shea VL, Berger JM, Dixon NE, van Oijen AM
Mechanisms of Regulation and Diverse Activities of Tau-Tubulin Kinase (TTBK) Isoforms.
1. Cell Mol Neurobiol - published May 1, 2020
2. Bao C, Bajrami B, Marcotte DJ, Chodaparambil JV, Kerns HM, Henderson J, Wei R, Gao B, Dillon GM
Structure and mechanism of human diacylglycerol O-acyltransferase 1.
1. Nature - published May 1, 2020
2. Wang L, Qian H, Nian Y, Han Y, Ren Z, Zhang H, Hu L, Prasad BVV, Laganowsky A, Yan N, Zhou M
RiboToolkit: an integrated platform for analysis and annotation of ribosome profiling data to decode mRNA translation at codon resolution.
1. Nucleic Acids Res - published May 1, 2020
2. Liu Q, Shvarts T, Sliz P, Gregory RI
Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel.
1. Cell Chem Biol - published May 1, 2020
2. Pantouris G, Khurana L, Ma A, Skeens E, Reiss K, Batista VS, Lisi GP, Lolis EJ
High-resolution cryo-EM reconstructions in the presence of substantial aberrations.
1. IUCrJ - published May 1, 2020
2. Bromberg R, Guo Y, Borek D, Otwinowski Z
HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis.
1. Mol Cell - published May 1, 2020
2. Bai G, Kermi C, Stoy H, Schiltz CJ, Bacal J, Zaino AM, Hadden MK, Eichman BF, Lopes M, Cimprich KA
mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding.
1. Elife - published May 1, 2020
2. Bao C, Loerch S, Ling C, Korostelev AA, Grigorieff N, Ermolenko DN
A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission.
1. Nat Struct Mol Biol - published May 1, 2020
2. Flower TG, Takahashi Y, Hudait A, Rose K, Tjahjono N, Pak AJ, Yokom AL, Liang X, Wang HG, Bouamr F, Voth GA, Hurley JH
Alternative splicing controls teneurin-latrophilin interaction and synapse specificity by a shape-shifting mechanism.
1. Nat Commun - published May 1, 2020
2. Li J, Xie Y, Cornelius S, Jiang X, Sando R, Kordon SP, Pan M, Leon K, Südhof TC, Zhao M, Araç D
A Single Shot Pre-fusion-Stabilized Bovine RSV F Vaccine is Safe and Effective in Newborn Calves with Maternally Derived Antibodies.
1. Vaccines (Basel) - published May 1, 2020
2. Riffault S, Hägglund S, Guzman E, Näslund K, Jouneau L, Dubuquoy C, Pietralunga V, Laubreton D, Boulesteix O, Gauthier D, Remot A, Boukaridi A, Falk A, Shevchenko G, Lind SB, Vargmar K, Zhang B, Kwong PD, Rodriguez MJ, Duran MG, Schwartz-Cornil I, Eléouët JF, Taylor G, Valarcher JF
19F NMR reveals the conformational properties of free thrombin and its zymogen precursor prethrombin-2.
1. J Biol Chem - published May 1, 2020
2. Ruben EA, Gandhi PS, Chen Z, Koester SK, DeKoster GT, Frieden C, Di Cera E
Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair.
1. Structure - published May 1, 2020
2. Trachman RJ 3rd, Cojocaru R, Wu D, Piszczek G, Ryckelynck M, Unrau PJ, Ferré-D'Amaré AR
Crystal structures of the sheeppoxvirus encoded inhibitor of apoptosis SPPV14 bound to Hrk and Bax BH3 peptides.
1. FEBS Lett - published May 1, 2020
2. Suraweera CD, Burton DR, Hinds MG, Kvansakul M
Gp41-targeted antibodies restore infectivity of a fusion-deficient HIV-1 envelope glycoprotein.
1. PLoS Pathog - published May 1, 2020
2. Joshi VR, Newman RM, Pack ML, Power KA, Munro JB, Okawa K, Madani N, Sodroski JG, Schmidt AG, Allen TM
The Synthesis and Anti-tumour Properties of Poly Ethoxy Ethyl Glycinamide (PEE-G) Scaffolds with Multiple PD-1 Peptides Attached.
1. ChemMedChem - published May 1, 2020
2. Shrestha R, Petley EV, Farrand KJ, Jamieson SA, Jiao W, Teesdale-Spittle PH, Hermans IF, Mace PD, Rendle PM
S-phase Enriched Non-coding RNAs Regulate Gene Expression and Cell Cycle Progression.
1. Cell Rep - published May 1, 2020
2. Yildirim O, Izgu EC, Damle M, Chalei V, Ji F, Sadreyev RI, Szostak JW, Kingston RE
A combinatorial view of old and new RNA polymerase II modifications.
1. Transcription - published May 1, 2020
2. Lyons DE, McMahon S, Ott M
Structure-Activity Relationship Study Reveals the Molecular Basis for Specific Sensing of Hydrophobic Amino Acids by the Campylobacter jejuni Chemoreceptor Tlp3.
1. Biomolecules - published May 1, 2020
2. Khan MF, Machuca MA, Rahman MM, Koç C, Norton RS, Smith BJ, Roujeinikova A
Chloroplast Sec14-like 1 (CPSFL1) is essential for normal chloroplast development and affects carotenoid accumulation in Chlamydomonas.
1. Proc Natl Acad Sci U S A - published May 1, 2020
2. García-Cerdán JG, Schmid EM, Takeuchi T, McRae I, McDonald KL, Yordduangjun N, Hassan AM, Grob P, Xu CS, Hess HF, Fletcher DA, Nogales E, Niyogi KK
Physician Assistant's Knowledge and Confidence Regarding Prescribing Pre-Exposure Prophylaxis for HIV Prevention.
1. Sex Transm Dis - published May 1, 2020
2. Bunting SR, Miller KW, Chappell R, Goldstein RH, DeJean O
Identification of Dengue Virus Serotype 3 Specific Antigenic Sites Targeted by Neutralizing Human Antibodies.
1. Cell Host Microbe - published May 1, 2020
2. Young E, Carnahan RH, Andrade DV, Kose N, Nargi RS, Fritch EJ, Munt JE, Doyle MP, White L, Baric TJ, Stoops M, DeSilva A, Tse LV, Martinez DR, Zhu D, Metz S, Wong MP, Espinosa DA, Montoya M, Biering SB, Sukulpolvi-Petty S, Kuan G, Balmaseda A, Diamond MS, Harris E, Crowe JE Jr, Baric RS
β-Arrestin-Biased Angiotensin II Receptor Agonists for COVID-19.
1. Circulation - published May 1, 2020
2. Manglik A, Wingler LM, Rockman HA, Lefkowitz RJ
Structural insight into tanapoxvirus mediated inhibition of apoptosis.
1. FEBS J - published May 1, 2020
2. Suraweera CD, Anasir MI, Chugh S, Javorsky A, Impey RE, Hasan Zadeh M, Soares da Costa TP, Hinds MG, Kvansakul M
De novo protein design enables the precise induction of RSV-neutralizing antibodies.
1. Science - published May 1, 2020
2. Sesterhenn F, Yang C, Bonet J, Cramer JT, Wen X, Wang Y, Chiang CI, Abriata LA, Kucharska I, Castoro G, Vollers SS, Galloux M, Dheilly E, Rosset S, Corthésy P, Georgeon S, Villard M, Richard CA, Descamps D, Delgado T, Oricchio E, Rameix-Welti MA, Más V, Ervin S, Eléouët JF, Riffault S, Bates JT, Julien JP, Li Y, Jardetzky T, Krey T, Correia BE
Optimizing the α1B-adrenergic receptor for solution NMR studies.
1. Biochim Biophys Acta Biomembr - published May 1, 2020
2. Schuster M, Deluigi M, Pantić M, Vacca S, Baumann C, Scott DJ, Plückthun A, Zerbe O
GemSpot: A Pipeline for Robust Modeling of Ligands into Cryo-EM Maps.
1. Structure - published May 1, 2020
2. Robertson MJ, van Zundert GCP, Borrelli K, Skiniotis G
Escherichia coli YcaQ is a DNA glycosylase that unhooks DNA interstrand crosslinks.
1. Nucleic Acids Res - published May 1, 2020
2. Bradley NP, Washburn LA, Christov PP, Watanabe CMH, Eichman BF
Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response.
1. Nat Commun - published May 1, 2020
2. Dufey E, Bravo-San Pedro JM, Eggers C, González-Quiroz M, Urra H, Sagredo AI, Sepulveda D, Pihán P, Carreras-Sureda A, Hazari Y, Sagredo EA, Gutierrez D, Valls C, Papaioannou A, Acosta-Alvear D, Campos G, Domingos PM, Pedeux R, Chevet E, Alvarez A, Godoy P, Walter P, Glavic A, Kroemer G, Hetz C
Mutation severity spectrum of rare alleles in the human genome is predictive of disease type.
1. PLoS Comput Biol - published May 1, 2020
2. Pei J, Kinch LN, Otwinowski Z, Grishin NV
Vinpocetine reduces cisplatin-induced acute kidney injury through inhibition of NF-κB pathway and activation of Nrf2/ARE pathway in rats.
1. Int Urol Nephrol - published May 1, 2020
2. Song W, Yin W, Ding L, Gao Y, Xu J, Yang Y, He X, Gong P, Wei L, Chen W, Zhang J
Development of CDK2 and CDK5 Dual Degrader TMX-2172.
1. Angew Chem Int Ed Engl - published May 1, 2020
2. Gray NS, Teng M, Jiang J, He Z, Kwiatkowski NP, Donovan KA, Mills CE, Victor C, Hatcher JM, Fischer ES, Sorger PK, Zhang T
Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance.
1. Commun Biol - published May 1, 2020
2. Gasparrini AJ, Markley JL, Kumar H, Wang B, Fang L, Irum S, Symister CT, Wallace M, Burnham CD, Andleeb S, Tolia NH, Wencewicz TA, Dantas G
The β-arrestin-biased β-adrenergic receptor blocker carvedilol enhances skeletal muscle contractility.
1. Proc Natl Acad Sci U S A - published May 1, 2020
2. Kim J, Grotegut CA, Wisler JW, Mao L, Rosenberg PB, Rockman HA, Lefkowitz RJ
Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane.
1. Proc Natl Acad Sci U S A - published May 1, 2020
2. Fang Z, Lee KY, Huo KG, Gasmi-Seabrook G, Zheng L, Moghal N, Tsao MS, Ikura M, Marshall CB
Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation.
1. Nat Commun - published May 1, 2020
2. Bamford NC, Le Mauff F, Van Loon JC, Ostapska H, Snarr BD, Zhang Y, Kitova EN, Klassen JS, Codée JDC, Sheppard DC, Howell PL
In Response to Regarding: Apoptosis Signaling Molecules as Treatment Targets in Head and Neck Squamous Carcinoma.
1. Laryngoscope - published May 1, 2020
2. Ow TJ, Thomas C, Fulcher CD, Chen J, López A, Reyna DE, Prystowsky MB, Smith RV, Schiff BA, Rosenblatt G, Belbin TJ, Harris TM, Childs GC, Kawachi N, Schlecht NF, Gavathiotis E