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35 Member Publications for July

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A convenient, reliable, and fast acoustic pressure field measurement method for magnetic resonance-guided high-intensity focused ultrasound systems with phased array transducers.
1. J Ther Ultrasound - published July 11, 2018
2. Kothapalli SVVN, Partanen A, Zhu L, Altman MB, Gach HM, Hallahan DE, Chen H
NSF-mediated disassembly of on and off-pathway SNARE complexes and inhibition by complexin.
1. Elife - published July 9, 2018
2. Choi UB, Zhao M, White KI, Pfuetzner RA, Esquivies L, Zhou Q, Brunger AT
Structural Insights from HIV-Antibody Co-Evolution and Related Immunization Studies.
1. AIDS Res Hum Retroviruses - published July 7, 2018
2. Zhou JO, Ton T, Morriss JW, Nguyen D, Fera D
Single-Particle Reconstruction of Biological Molecules-Story in a Sample (Nobel Lecture).
1. Angew Chem Int Ed Engl - published July 6, 2018
2. Frank J
Discovery of a Highly Potent and Broadly Effective EGFR and HER2 Exon 20 Insertion Mutant Inhibitor.
1. Angew Chem Int Ed Engl - published July 6, 2018
2. Jang J, Son J, Park E, Kosaka T, Saxon JA, De Clercq D, Choi HG, Tanizaki J, Eck MJ, Jänne PA, Gray NS
Lipids surf the groove in scramblases.
1. Proc Natl Acad Sci U S A - published July 6, 2018
2. Ballesteros A, Swartz KJ
Discovery of Mcl-1 inhibitors from integrated high throughput and virtual screening.
1. Sci Rep - published July 5, 2018
2. Mady ASA, Liao C, Bajwa N, Kump KJ, Abulwerdi FA, Lev KL, Miao L, Grigsby SM, Perdih A, Stuckey JA, Du Y, Fu H, Nikolovska-Coleska Z
The N-terminal region of photocleavable peptides that bind HLA-DR1 determines the kinetics of fragment release.
1. PLoS One - published July 3, 2018
2. Negroni MP, Stern LJ
Development of Endocyclic Control Elements for Peptide Macrocycles.
1. J Am Chem Soc - published July 3, 2018
2. Appavoo SD, Kaji T, Frost JR, Scully CCG, Yudin AK
Solid State NMR Studies of Intact Lipopolysaccharide Endotoxin.
1. ACS Chem Biol - published July 2, 2018
2. Laguri C, Silipo A, Martorana AM, Schanda P, Marchetti R, Polissi A, Molinaro A, Simorre JP
Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4.
1. Nat Struct Mol Biol - published July 2, 2018
2. Bodnar NO, Kim KH, Ji Z, Wales TE, Svetlov V, Nudler E, Engen JR, Walz T, Rapoport TA
Sustainable Syntheses of (-)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site.
1. Sci Rep - published July 1, 2018
2. Smedley CJ, Stanley PA, Qazzaz ME, Prota AE, Olieric N, Collins H, Eastman H, Barrow AS, Lim KH, Kam TS, Smith BJ, Duivenvoorden HM, Parker BS, Bradshaw TD, Steinmetz MO, Moses JE
P2X7R mutation disrupts the NLRP3-mediated Th program and predicts poor cardiac allograft outcomes.
1. J Clin Invest - published July 1, 2018
2. D'Addio F, Vergani A, Potena L, Maestroni A, Usuelli V, Ben Nasr M, Bassi R, Tezza S, Dellepiane S, El Essawy B, Iascone M, Iacovoni A, Borgese L, Liu K, Visner G, Dhe-Paganon S, Corradi D, Abdi R, Starling RC, Folli F, Zuccotti GV, Sayegh MH, Heeger PS, Chandraker A, Grigioni F, Fiorina P
Metalloenzymes in natural product biosynthetic pathways.
1. Nat Prod Rep - published July 1, 2018
2. Ryan KS, Drennan CL
Structure of the Human cGAS-DNA Complex Reveals Enhanced Control of Immune Surveillance.
1. Cell - published July 1, 2018
2. Zhou W, Whiteley AT, de Oliveira Mann CC, Morehouse BR, Nowak RP, Fischer ES, Gray NS, Mekalanos JJ, Kranzusch PJ
Mass spectrometry quantitation of proteins from small pools of developing auditory and vestibular cells.
1. Sci Data - published July 1, 2018
2. Krey JF, Scheffer DI, Choi D, Reddy A, David LL, Corey DP, Barr-Gillespie PG
Disorder at the Tips of a Disease-Relevant Aβ42 Amyloid Fibril: A Molecular Dynamics Study.
1. J Phys Chem B - published July 1, 2018
2. Ilie IM, Caflisch A
Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin.
1. Sci Rep - published July 1, 2018
2. Debela M, Magdolen V, Skala W, Elsässer B, Schneider EL, Craik CS, Biniossek ML, Schilling O, Bode W, Brandstetter H, Goettig P
Coherent feedforward regulation of gene expression by Caulobacter σT and GsrN during hyperosmotic stress.
1. J Bacteriol - published July 1, 2018
2. Tien MZ, Stein BJ, Crosson S
A simple and robust procedure for preparing graphene-oxide cryo-EM grids.
1. J Struct Biol - published July 1, 2018
2. Palovcak E, Wang F, Zheng SQ, Yu Z, Li S, Betegon M, Bulkley D, Agard DA, Cheng Y
Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation.
1. MBio - published July 1, 2018
2. Klein RD, Shu Q, Cusumano ZT, Nagamatsu K, Gualberto NC, Lynch AJL, Wu C, Wang W, Jain N, Pinkner JS, Amarasinghe GK, Hultgren SJ, Frieden C, Chapman MR
A Mechanistic Model for the Aziridine Aldehyde-Driven Macrocyclization of Peptides.
1. J Org Chem - published July 1, 2018
2. Belding L, Zaretsky S, Yudin AK, Dudding T
SOSIP changes affect human immunodeficiency virus (HIV-1) envelope glycoprotein conformation and CD4 engagement.
1. J Virol - published July 1, 2018
2. Alsahafi N, Anand SP, Castillo-Menendez L, Verly MM, Medjahed H, Prévost J, Herschhorn A, Richard J, Schön A, Melillo B, Freire E, Smith AB 3rd, Sodroski J, Finzi A
Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection.
1. Trends Cancer - published July 1, 2018
2. Huang CH, Lee KC, Doudna JA
Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro.
1. Proc Natl Acad Sci U S A - published July 1, 2018
2. Gee MH, Sibener LV, Birnbaum ME, Jude KM, Yang X, Fernandes RA, Mendoza JL, Glassman CR, Garcia KC
SIMBAD: a sequence-independent molecular-replacement pipeline.
1. Acta Crystallogr D Struct Biol - published July 1, 2018
2. Simpkin AJ, Simkovic F, Thomas JMH, Savko M, Lebedev A, Uski V, Ballard C, Wojdyr M, Wu R, Sanishvili R, Xu Y, Lisa MN, Buschiazzo A, Shepard W, Rigden DJ, Keegan RM
Author Correction: Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding.
1. Nat Commun - published July 1, 2018
2. Guo HF, Tsai CL, Terajima M, Tan X, Banerjee P, Miller MD, Liu X, Yu J, Byemerwa J, Alvarado S, Kaoud TS, Dalby KN, Bota-Rabassedas N, Chen Y, Yamauchi M, Tainer JA, Phillips GN Jr, Kurie JM
Cryo-EM structure of a fungal mitochondrial calcium uniporter.
1. Nature - published July 1, 2018
2. Nguyen NX, Armache JP, Lee C, Yang Y, Zeng W, Mootha VK, Cheng Y, Bai XC, Jiang Y
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes.
1. Elife - published July 1, 2018
2. Sorger PK, Lin JR, Izar B, Wang S, Yapp C, Mei S, Shah PM, Santagata S
Ligand-Mediated Biofilm Formation via Enhanced Physical Interaction between a Diguanylate Cyclase and Its Receptor.
1. MBio - published July 1, 2018
2. Giacalone D, Smith TJ, Collins AJ, Sondermann H, Koziol LJ, O'Toole GA
Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling.
1. J Med Chem - published July 1, 2018
2. Abbott JR, Hodges TR, Daniels RN, Patel PA, Kennedy JP, Howes JE, Akan DT, Burns MC, Sai J, Sobolik T, Beesetty Y, Lee T, Rossanese OW, Phan J, Waterson AG, Fesik SW
How small-molecule inhibitors of dengue-virus infection interfere with viral membrane fusion.
1. Elife - published July 1, 2018
2. Chao LH, Jang J, Johnson A, Nguyen A, Gray N, Yang PL, Harrison SC
Identification of ions in experimental electrostatic potential maps.
1. IUCrJ - published July 1, 2018
2. Wang J, Liu Z, Frank J, Moore PB
MR1 displays the microbial metabolome driving selective MR1-restricted T cell receptor usage.
1. Sci Immunol - published July 1, 2018
2. Harriff MJ, McMurtrey C, Froyd CA, Jin H, Cansler M, Null M, Worley A, Meermeier EW, Swarbrick G, Nilsen A, Lewinsohn DA, Hildebrand W, Adams EJ, Lewinsohn DM
Calprotectin protects against experimental colonic inflammation in mice.
1. Br J Pharmacol - published July 1, 2018
2. Aranda CJ, Ocón B, Arredondo-Amador M, Suárez MD, Zarzuelo A, Chazin WJ, Martínez-Augustin O, de Medina FS

Member Publications

35 Member Publications for July

A convenient, reliable, and fast acoustic pressure field measurement method for magnetic resonance-guided high-intensity focused ultrasound systems with phased array transducers.

NSF-mediated disassembly of on and off-pathway SNARE complexes and inhibition by complexin.

Structural Insights from HIV-Antibody Co-Evolution and Related Immunization Studies.

Single-Particle Reconstruction of Biological Molecules-Story in a Sample (Nobel Lecture).

Discovery of a Highly Potent and Broadly Effective EGFR and HER2 Exon 20 Insertion Mutant Inhibitor.

Lipids surf the groove in scramblases.

Discovery of Mcl-1 inhibitors from integrated high throughput and virtual screening.

The N-terminal region of photocleavable peptides that bind HLA-DR1 determines the kinetics of fragment release.

Development of Endocyclic Control Elements for Peptide Macrocycles.

Solid State NMR Studies of Intact Lipopolysaccharide Endotoxin.

Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4.

Sustainable Syntheses of (-)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site.

P2X7R mutation disrupts the NLRP3-mediated Th program and predicts poor cardiac allograft outcomes.

Metalloenzymes in natural product biosynthetic pathways.

Structure of the Human cGAS-DNA Complex Reveals Enhanced Control of Immune Surveillance.

Mass spectrometry quantitation of proteins from small pools of developing auditory and vestibular cells.

Disorder at the Tips of a Disease-Relevant Aβ42 Amyloid Fibril: A Molecular Dynamics Study.

Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin.

Coherent feedforward regulation of gene expression by <i>Caulobacter</i> σ<sup>T</sup> and GsrN during hyperosmotic stress.

A simple and robust procedure for preparing graphene-oxide cryo-EM grids.

Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation.

A Mechanistic Model for the Aziridine Aldehyde-Driven Macrocyclization of Peptides.

SOSIP changes affect human immunodeficiency virus (HIV-1) envelope glycoprotein conformation and CD4 engagement.

Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection.

Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro.

SIMBAD: a sequence-independent molecular-replacement pipeline.

Author Correction: Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe<sup>2+</sup>-binding.

Cryo-EM structure of a fungal mitochondrial calcium uniporter.

Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes.

Ligand-Mediated Biofilm Formation via Enhanced Physical Interaction between a Diguanylate Cyclase and Its Receptor.

Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling.

How small-molecule inhibitors of dengue-virus infection interfere with viral membrane fusion.

Identification of ions in experimental electrostatic potential maps.

MR1 displays the microbial metabolome driving selective MR1-restricted T cell receptor usage.

Calprotectin protects against experimental colonic inflammation in mice.