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98 Member Publications for July

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Nematocida displodere mechanosensitive ion channel of small conductance 2 assembles into a unique 6-channel super-structure in vitro.
1. PLoS One - published July 22, 2024
2. Berg A, Berntsson RP, Barandun J
Functional and structural insights into RAS effector proteins.
1. Mol Cell - published July 9, 2024
2. Mozzarelli AM, Simanshu DK, Castel P
POTRA domains of the TamA insertase interact with the outer membrane and modulate membrane properties.
1. Proc Natl Acad Sci U S A - published July 9, 2024
2. Mellouk A, Jaouen P, Ruel LJ, Lê M, Martini C, Moraes TF, El Bakkouri M, Lagüe P, Boisselier E, Calmettes C
Roles for PMP22 in Schwann cell cholesterol homeostasis in health and disease.
1. Biochem Soc Trans - published July 9, 2024
2. Stefanski KM, Wilkinson MC, Sanders CR
Assessing and engineering the IscB-ωRNA system for programmed genome editing.
1. Nat Chem Biol - published July 8, 2024
2. Yan H, Tan X, Zou S, Sun Y, Ke A, Tang W
CRISPR-based rapid molecular diagnostic tests for fusion-driven leukemias.
1. Blood - published July 8, 2024
2. Vedula RS, Karp HQ, Koob J, Lim F, Garcia JS, Winer ES, Luskin MR, Ghiaur G, Kim AS, Beppu LW, Sala-Torra O, Radich JP, Gootenberg JS, Abudayyeh O, Zhang F, Lindsley RC
Covalent isothiocyanate inhibitors of macrophage migration inhibitory factor as potential colorectal cancer treatments.
1. ChemMedChem - published July 8, 2024
2. Tyndall J, Putha L, Kok LK, Fellner M, Rutledge MT, Gamble AB, Wilbanks SM, Vernall AJ
The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation.
1. Cell Rep - published July 8, 2024
2. Xiao YX, Lee SY, Aguilera-Uribe M, Samson R, Au A, Khanna Y, Liu Z, Cheng R, Aulakh K, Wei J, Farias AG, Reilly T, Birkadze S, Habsid A, Brown KR, Chan K, Mero P, Huang JQ, Billmann M, Rahman M, Myers C, Andrews BJ, Youn JY, Yip CM, Rotin D, Derry WB, Forman-Kay JD, Moses AM, Pritišanac I, Gingras AC, Moffat J
Chromosome compaction is triggered by an autonomous DNA-binding module within condensin.
1. Cell Rep - published July 8, 2024
2. Pastic A, Nosella ML, Kochhar A, Liu ZH, Forman-Kay JD, D'Amours D
Development and Characterization of 50 nanometer diameter Genetically Encoded Multimeric Nanoparticles.
1. bioRxiv - published July 7, 2024
2. Hernandez CM, Duran-Chaparro DC, van Eeuwen T, Rout MP, Holt LJ
TRPML1 gating modulation by allosteric mutations and lipids (Design of allosteric mutations that recapitulate the gating of TRPML1 ).
1. bioRxiv - published July 6, 2024
2. Gan N, Han Y, Zeng W, Jiang Y
The GoldX Fiducial Eraser.
1. Int J Mol Sci - published July 6, 2024
2. Van Blerkom P, Bezault A, Sauvanet C, Hanein D, Volkmann N
Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels.
1. bioRxiv - published July 5, 2024
2. Giese APJ, Weng WH, Kindt KS, Chang HHV, Montgomery JS, Ratzan EM, Beirl AJ, Rivera RA, Lotthammer JM, Walujkar S, Foster MP, Zobeiri OA, Holt JR, Riazuddin S, Cullen KE, Sotomayor M, Ahmed ZM
An intron endonuclease facilitates interference competition between coinfecting viruses.
1. Science - published July 5, 2024
2. Birkholz EA, Morgan CJ, Laughlin TG, Lau RK, Prichard A, Rangarajan S, Meza GN, Lee J, Armbruster E, Suslov S, Pogliano K, Meyer JR, Villa E, Corbett KD, Pogliano J
An αIIbβ3 Monoclonal Antibody Traps a Semi-Extended Conformation and Allosterically Inhibits Large Ligand Binding.
1. Blood Adv - published July 5, 2024
2. Wang L, Wang J, Li J, Walz T, Coller BS
Amino Acids and Their Biological Derivatives Modulate Protein-Protein Interactions in an Additive Way.
1. J Phys Chem Lett - published July 5, 2024
2. Xu X, Stellacci F
Protocol to detect and quantify interactions between proteins expressed in Drosophila S2 cells.
1. STAR Protoc - published July 5, 2024
2. DeOliveira CC, Lin C, Crane BR
Memantine Inhibits Calcium-Permeable AMPA Receptors.
1. bioRxiv - published July 4, 2024
2. Carrillo E, Montaño Romero A, Gonzalez CU, Turcu AL, Chen SR, Chen H, Pan HL, Vázquez S, Twomey EC, Jayaraman V
NF-κB inhibitor alpha controls SARS-CoV-2 infection in ACE2-overexpressing human airway organoids.
1. Sci Rep - published July 4, 2024
2. Simoneau CR, Chen PY, Xing GK, Hayashi JM, Chen IP, Khalid MM, Meyers NL, Taha TY, Leon KE, Suryawanshi RK, McCavitt-Malvido M, Ashuach T, Fontaine KA, Rodriguez L, Joehnk B, Walcott K, Vasudevan S, Fang X, Maishan M, Schultz S, Roose JP, Matthay MA, Sil A, Arjomandi M, Yosef N, Ott M
Zfp106 binds to G-quadruplex RNAs and inhibits RAN translation and formation of RNA foci caused by G4C2 repeats.
1. Proc Natl Acad Sci U S A - published July 3, 2024
2. Celona B, Salomonsson SE, Wu H, Dang B, Kratochvil HT, Clelland CD, DeGrado WF, Black BL
A µ-opioid receptor modulator that works cooperatively with naloxone.
1. Nature - published July 3, 2024
2. O'Brien ES, Rangari VA, El Daibani A, Eans SO, Hammond HR, White E, Wang H, Shiimura Y, Krishna Kumar K, Jiang Q, Appourchaux K, Huang W, Zhang C, Kennedy BJ, Mathiesen JM, Che T, McLaughlin JP, Majumdar S, Kobilka BK
High-Density Lipoprotein Particle Concentration and Size Predict Incident Coronary Artery Disease Events in a Cohort With Type 1 Diabetes.
1. J Am Heart Assoc - published July 3, 2024
2. Costacou T, Vaisar T, Miller RG, Davidson WS, Heinecke JW, Orchard TJ, Bornfeldt KE
DCAF15 control of cohesin dynamics sustains acute myeloid leukemia.
1. Nat Commun - published July 3, 2024
2. Grothusen GP, Chang R, Cao Z, Zhou N, Mittal M, Datta A, Wulfridge P, Beer T, Wang B, Zheng N, Tang HY, Sarma K, Greenberg RA, Shi J, Busino L
Design, Synthesis, and Characterization of New δ Opioid Receptor-Selective Fluorescent Probes and Applications in Single-Molecule Microscopy of Wild-Type Receptors.
1. J Med Chem - published July 2, 2024
2. Drakopoulos A, Koszegi Z, Seier K, Hübner H, Maurel D, Sounier R, Granier S, Gmeiner P, Calebiro D, Decker M
Versatile roles of protein flavinylation in bacterial extracyotosolic electron transfer.
1. mSystems - published July 2, 2024
2. Huang S, Méheust R, Barquera B, Light SH
Dissemination of pathogenic bacteria is reinforced by a MARTX toxin effector duet.
1. Nat Commun - published July 2, 2024
2. Choi S, Lee Y, Park S, Jang SY, Park J, Oh DW, Kim SM, Kim TH, Lee GS, Cho C, Kim BS, Lee D, Kim EH, Cheong HK, Moon JH, Song JJ, Hwang J, Kim MH
SARS-CoV-2 monoclonal antibody treatment followed by vaccination shifts human memory B cell epitope recognition suggesting antibody feedback.
1. J Infect Dis - published July 2, 2024
2. Bloom N, Ramirez SI, Cohn H, Parikh UM, Heaps A, Sieg SF, Greninger A, Ritz J, Moser C, Eron JJ, Bajic G, Currier JS, Klekotka P, Wohl DA, Daar ES, Li J, Hughes MD, Chew KW, Smith DM, Crotty S, Coelho CH, Accelerating COVID-19 Therapeutic Interventions and Vaccines–2/A5401 (ACTIV-2/A5401) Study Team
Time-Resolved Ion Mobility-Mass Spectrometry Reveals Structural Transitions in the Disassembly of Modular Polyketide Syntheses.
1. J Am Soc Mass Spectrom - published July 2, 2024
2. Zhao C, Slocum ST, Sherman DH, Ruotolo BT
Click editing enables programmable genome writing using DNA polymerases and HUH endonucleases.
1. Nat Biotechnol - published July 2, 2024
2. Ferreira da Silva J, Tou CJ, King EM, Eller ML, Rufino-Ramos D, Ma L, Cromwell CR, Metovic J, Benning FMC, Chao LH, Eichler FS, Kleinstiver BP
Multimerization of TREM2 is impaired by Alzheimer's disease-associated variants.
1. Alzheimers Dement - published July 2, 2024
2. Dean HB, Greer RA, Yang SZ, Elston DS, Brett TJ, Roberson ED, Song Y
Conformational dynamics underlying atypical chemokine receptor 3 activation.
1. Proc Natl Acad Sci U S A - published July 2, 2024
2. Otun O, Aljamous C, Del Nero E, Arimont-Segura M, Bosma R, Zarzycka B, Girbau T, Leyrat C, de Graaf C, Leurs R, Durroux T, Granier S, Cong X, Bechara C
Modular binder technology by NGS-aided, high-resolution selection in yeast of designed armadillo modules.
1. Proc Natl Acad Sci U S A - published July 2, 2024
2. Stark Y, Menard F, Jeliazkov JR, Ernst P, Chembath A, Ashraf M, Hine AV, Plückthun A
An interstrand DNA crosslink glycosylase aids Acinetobacter baumannii pathogenesis.
1. Proc Natl Acad Sci U S A - published July 2, 2024
2. Kunkle DE, Cai Y, Eichman BF, Skaar EP
Nanoscale architecture of synaptic vesicles and scaffolding complexes revealed by cryo-electron tomography.
1. Proc Natl Acad Sci U S A - published July 2, 2024
2. Held RG, Liang J, Brunger AT
Lrp10 suppresses IL7R limiting CD8 T cell homeostatic expansion and anti-tumor immunity.
1. EMBO Rep - published July 2, 2024
2. Russell J, Chen L, Liu A, Wang J, Ghosh S, Zhong X, Shi H, Beutler B, Nair-Gill E
Structure and RNA-binding of the helically extended Roquin CCCH-type zinc finger.
1. Nucleic Acids Res - published July 2, 2024
2. Tants JN, Oberstrass L, Weigand JE, Schlundt A
Observing isolated synaptic vesicle association and fusion ex vivo.
1. Nat Protoc - published July 2, 2024
2. Leitz J, Wang C, Esquivies L, Peters JJ, Gopal N, Pfuetzner RA, Wang AL, Brunger AT
Protocol for phospho-SrcKD: rPTPεD1 complex preparation and BLI binding assays to demonstrate their exosite interface.
1. STAR Protoc - published July 2, 2024
2. EswarKumar N, TewarySunil K, Ho MC
CCAR1 promotes DNA repair via alternative splicing.
1. Mol Cell - published July 2, 2024
2. Karasu ME, Jahnke L, Joseph BJ, Amerzhanova Y, Mironov A, Shu X, Schröder MS, Gvozdenovic A, Sala I, Zavolan M, Jonas S, Corn JE
Low power supercycled TPPM decoupling.
1. J Magn Reson - published July 2, 2024
2. Garg R, DeZonia B, Paterson AL, Rienstra CM
Global siRNA Screen Reveals Critical Human Host Factors of SARS-CoV-2 Multicycle Replication.
1. bioRxiv - published July 1, 2024
2. Yin X, Pu Y, Yuan S, Pache L, Churas C, Weston S, Riva L, Simons LM, Cisneros WJ, Clausen T, De Jesus PD, Kim HN, Fuentes D, Whitelock J, Esko J, Lord M, Mena I, García-Sastre A, Hultquist JF, Frieman MB, Ideker T, Pratt D, Martin-Sancho L, Chanda SK
Proteostasis Landscapes of Selective versus Poorly Responsive CFTR Variants Reveals Structural Vulnerabilities to Correction.
1. bioRxiv - published July 1, 2024
2. McDonald EF, Kim M, Olson JA 3rd, Meiler J, Plate L
Structural Biology in Drug Discovery and Development: Call for Papers.
1. J Med Chem - published July 1, 2024
2. Heppner DE, Bigi-Botterill SV, Riley AP, Chibale K, Lindsley CW
Advancements in Ligand-Based Virtual Screening through the Synergistic Integration of Graph Neural Networks and Expert-Crafted Descriptors.
1. bioRxiv - published July 1, 2024
2. Liu YL, Moretti R, Wang Y, Dong H, Yan B, Bodenheimer B, Derr T, Meiler J
Protein-protein interactions in the core nucleotide excision repair pathway.
1. DNA Repair (Amst) - published July 1, 2024
2. D'Souza A, Kim M, Chazin WJ, Schärer OD
Ligify: Automated Genome Mining for Ligand-Inducible Transcription Factors.
1. ACS Synth Biol - published July 1, 2024
2. d'Oelsnitz S, Love JD, Ellington AD, Ross D
Protein semisynthesis reveals plasticity in HECT E3 ubiquitin ligase mechanisms.
1. Nat Chem - published July 1, 2024
2. Jiang H, Miller BD, Viennet T, Kim H, Lee K, Arthanari H, Cole PA
Development of covalent chemogenetic K(2P) channel activators.
1. Cell Chem Biol - published July 1, 2024
2. Deal PE, Lee H, Mondal A, Lolicato M, Mendonça PRF, Black H, Jang S, El-Hilali X, Bryant C, Isacoff EY, Renslo AR, Minor DL Jr
Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation.
1. Cell Rep - published July 1, 2024
2. Zhang P, Gorman J, Tsybovsky Y, Lu M, Liu Q, Gopan V, Singh M, Lin Y, Miao H, Seo Y, Kwon A, Olia AS, Chuang GY, Geng H, Lai YT, Zhou T, Mascola JR, Mothes W, Kwong PD, Lusso P
Allosteric activation of the co-receptor BAK1 by the EFR receptor kinase initiates immune signaling.
1. Elife - published July 1, 2024
2. Mühlenbeck H, Tsutsui Y, Lemmon MA, Bender KW, Zipfel C
Mucosal signatures of pathogenic T cells in HLA-B*27+ anterior uveitis and axial spondyloarthritis.
1. JCI Insight - published July 1, 2024
2. Paley MA, Yang X, Hassman LM, Penkava F, Garner LI, Paley GL, Linskey N, Agnew R, Arantes de Faria PH, Feng A, Li SY, Simone D, Roberson ED, Ruzycki PA, Esaulova E, Laurent J, Feigl-Lenzen L, Springer LE, Liu C, Gillespie GM, Bowness P, Garcia KC, Yokoyama WM
Combined clinical, structural, and cellular studies discriminate pathogenic and benign TRPV4 variants.
1. Brain - published July 1, 2024
2. Berth SH, Vo L, Kwon DH, Grider T, Damayanti YS, Kosmanopoulos G, Fox A, Lau AR, Carr P, Donohue JK, Hoke M, Thomas S, Karim C, Fay AJ, Meltzer E, Crawford TO, Gaudet R, Shy ME, Hellmich UA, Lee SY, Sumner CJ, McCray BA
Molecular basis and functional consequences of the interaction between the Base Excision Repair DNA glycosylase NEIL1 and RPA.
1. J Biol Chem - published July 1, 2024
2. Le Meur RA, Pecen TJ, Le Meur KV, Nagel ZD, Chazin WJ
They all rock: A systematic comparison of conformational movements in LeuT-fold transporters.
1. Structure - published July 1, 2024
2. Licht JA, Berry SP, Gutierrez MA, Gaudet R
Tubulin code eraser CCP5 binds branch glutamates by substrate deformation.
1. Nature - published July 1, 2024
2. Chen J, Zehr EA, Gruschus JM, Szyk A, Liu Y, Tanner ME, Tjandra N, Roll-Mecak A
In vitro higher-order oligomeric assembly of the respiratory syncytial virus M2-1 protein with longer RNAs.
1. J Virol - published July 1, 2024
2. Gao Y, Raghavan A, Espinosa Garcia SA, Deng B, Hurtado de Mendoza D, Liang B
A eukaryotic-like ubiquitination system in bacterial antiviral defence.
1. Nature - published July 1, 2024
2. Chambers LR, Ye Q, Cai J, Gong M, Ledvina HE, Zhou H, Whiteley AT, Suhandynata RT, Corbett KD
Antibodies targeting the glycan cap of Ebola virus glycoprotein are potent inducers of the complement.
1. Commun Biol - published July 1, 2024
2. Ilinykh PA, Huang K, Gunn BM, Kuzmina NA, Kedarinath K, Jurado-Cobena E, Zhou F, Subramani C, Hyde MA, Velazquez JV, Williamson LE, Gilchuk P, Carnahan RH, Alter G, Crowe JE Jr, Bukreyev A
Rational correction of pathogenic conformational defects in HTRA1.
1. Nat Commun - published July 1, 2024
2. Beaufort N, Ingendahl L, Merdanovic M, Schmidt A, Podlesainski D, Richter T, Neumann T, Kuszner M, Vetter IR, Stege P, Burston SG, Filipovic A, Ruiz-Blanco YB, Bravo-Rodriguez K, Mieres-Perez J, Beuck C, Uebel S, Zobawa M, Schillinger J, Malik R, Todorov-Völgyi K, Rey J, Roberti A, Hagemeier B, Wefers B, Müller SA, Wurst W, Sanchez-Garcia E, Zimmermann A, Hu XY, Clausen T, Huber R, Lichtenthaler SF, Schmuck C, Giese M, Kaiser M, Ehrmann M, Dichgans M
A systematic search for RNA structural switches across the human transcriptome.
1. Nat Methods - published July 1, 2024
2. Khoroshkin M, Asarnow D, Zhou S, Navickas A, Winters A, Goudreau J, Zhou SK, Yu J, Palka C, Fish L, Borah A, Yousefi K, Carpenter C, Ansel KM, Cheng Y, Gilbert LA, Goodarzi H
Structural basis of homodimerization of the JNK scaffold protein JIP2 and its heterodimerization with JIP1.
1. Structure - published July 1, 2024
2. Mariño Pérez L, Ielasi FS, Lee A, Delaforge E, Juyoux P, Tengo M, Davis RJ, Palencia A, Jensen MR
Structure and in vivo psoralen DNA crosslink repair activity of mycobacterial Nei2.
1. mBio - published July 1, 2024
2. Warren GM, Shuman S
Kinetic and structural insights into the requirement of fungal tRNA ligase for a 2'-phosphate end.
1. RNA - published July 1, 2024
2. Ghosh S, Shuman S
Two-Metal Ion Mechanism of DNA Cleavage by Activated, Filamentous SgrAI.
1. J Biol Chem - published July 1, 2024
2. Shan Z, Rivero-Gamez A, Lyumkis D, Horton NC
Native mass spectrometry and structural studies reveal modulation of MsbA-nucleotide interactions by lipids.
1. Nat Commun - published July 1, 2024
2. Zhang T, Lyu J, Yang B, Yun SD, Scott E, Zhao M, Laganowsky A
An exopolysaccharide pathway from a freshwater Sphingomonas isolate.
1. J Bacteriol - published July 1, 2024
2. Goetsch AG, Ufearo D, Keiser G, Heiss C, Azadi P, Hershey DM
Control of G protein-coupled receptor function via membrane-interacting intrinsically disordered C-terminal domains.
1. Proc Natl Acad Sci U S A - published July 1, 2024
2. Mancinelli CD, Marx DC, Gonzalez-Hernandez AJ, Huynh K, Mancinelli L, Arefin A, Khelashvilli G, Levitz J, Eliezer D
The West Nile virus genome harbors essential riboregulatory elements with conserved and host-specific functional roles.
1. Proc Natl Acad Sci U S A - published July 1, 2024
2. Huston NC, Tsao LH, Brackney DE, Pyle AM
Structure of the flotillin complex in a native membrane environment.
1. Proc Natl Acad Sci U S A - published July 1, 2024
2. Fu Z, MacKinnon R
Assembly of respiratory syncytial virus matrix protein lattice and its coordination with fusion glycoprotein trimers.
1. Nat Commun - published July 1, 2024
2. Sibert BS, Kim JY, Yang JE, Ke Z, Stobart CC, Moore ML, Wright ER
Polymerization of ZBTB transcription factors regulates chromatin occupancy.
1. Mol Cell - published July 1, 2024
2. Park PMC, Park J, Brown J, Hunkeler M, Roy Burman SS, Donovan KA, Yoon H, Nowak RP, Słabicki M, Ebert BL, Fischer ES
Conformation of factor Xa in solution revealed by single molecule spectroscopy.
1. J Thromb Haemost - published July 1, 2024
2. Stojanovski BM, Di Cera E
Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38.
1. Cell Rep - published July 1, 2024
2. Shin OS, Monticelli SR, Hjorth CK, Hornet V, Doyle M, Abelson D, Kuehne AI, Wang A, Bakken RR, Mishra AK, Middlecamp M, Champney E, Stuart L, Maurer DP, Li J, Berrigan J, Barajas J, Balinandi S, Lutwama JJ, Lobel L, Zeitlin L, Walker LM, Dye JM, Chandran K, Herbert AS, Pauli NT, McLellan JS
Modulating Weak Protein-Protein Cross-Interactions by the Addition of Free Amino Acids at Millimolar Concentrations.
1. J Phys Chem B - published July 1, 2024
2. Winkler PM, Siri C, Buczkowski J, V C Silva J, Bovetto L, Schmitt C, Stellacci F
Discovery of Uncommon Tryptophan-Containing Diketopiperazines from Aspergillus homomorphus CBS 101889 Using an Aspergillus nidulans Heterologous Expression System.
1. J Nat Prod - published July 1, 2024
2. Jenkinson CB, Lin SY, Villarreal M, Oakley CE, Sherman DH, Lee CK, Wang CCC, Oakley BR
Phospho-KNL-1 recognition by a TPR domain targets the BUB-1-BUB-3 complex to C. elegans kinetochores.
1. J Cell Biol - published July 1, 2024
2. Houston J, Vissotsky C, Deep A, Hakozaki H, Crews E, Oegema K, Corbett KD, Lara-Gonzalez P, Kim T, Desai A
Determinants of minor satellite RNA function in chromosome segregation in mouse embryonic stem cells.
1. J Cell Biol - published July 1, 2024
2. Chen YL, Jones AN, Crawford A, Sattler M, Ettinger A, Torres-Padilla ME
The oligomeric states of dye-decolorizing peroxidases from Streptomyces lividans and their implications for mechanism of substrate oxidation.
1. Protein Sci - published July 1, 2024
2. Lučić M, Allport T, Clarke TA, Williams LJ, Wilson MT, Chaplin AK, Worrall JAR
A new lysine biosynthetic enzyme from a bacterial endosymbiont shaped by genetic drift and genome reduction.
1. Protein Sci - published July 1, 2024
2. Gilkes JM, Frampton RA, Board AJ, Hudson AO, Price TG, Morris VK, Crittenden DL, Muscroft-Taylor AC, Sheen CR, Smith GR, Dobson RCJ
Assessing the functional roles of coevolving PHD finger residues.
1. Protein Sci - published July 1, 2024
2. Basu S, Subedi U, Tonelli M, Afshinpour M, Tiwari N, Fuentes EJ, Chakravarty S
Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy.
1. Nat Struct Mol Biol - published July 1, 2024
2. Saecker RM, Mueller AU, Malone B, Chen J, Budell WC, Dandey VP, Maruthi K, Mendez JH, Molina N, Eng ET, Yen LY, Potter CS, Carragher B, Darst SA
VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates.
1. Nat Cell Biol - published July 1, 2024
2. Wang C, Zhang K, Cai B, Haller JE, Carnazza KE, Hu J, Zhao C, Tian Z, Hu X, Hall D, Qiang J, Hou S, Liu Z, Gu J, Zhang Y, Seroogy KB, Burré J, Fang Y, Liu C, Brunger AT, Li D, Diao J
Conserved C-Terminal Tail Is Responsible for Membrane Localization and Function of Pseudomonas aeruginosa Hemerythrin.
1. Biochemistry - published July 1, 2024
2. Stuut Balsam S, Zhong F, Pence N, Levintov L, Andhare D, Hammond JH, Ragusa MJ, Vashisth H, Hogan DA, Pletneva EV
Structural basis for Mis18 complex assembly and its implications for centromere maintenance.
1. EMBO Rep - published July 1, 2024
2. Thamkachy R, Medina-Pritchard B, Park SH, Chiodi CG, Zou J, de la Torre-Barranco M, Shimanaka K, Abad MA, Gallego Páramo C, Feederle R, Ruksenaite E, Heun P, Davies OR, Rappsilber J, Schneidman-Duhovny D, Cho US, Jeyaprakash AA
Limitations and Potential of κOR Biased Agonists for Pain and Itch Management.
1. Neuropharmacology - published July 1, 2024
2. El Daiban A, Madasu M, Al-Hasani R, Che T
Bridging the microscopic divide: a comprehensive overview of micro-crystallization and in vivo crystallography.
1. IUCrJ - published July 1, 2024
2. Chavas LMG, Coulibaly F, Garriga D
Comprehensive encoding of conformational and compositional protein structural ensembles through the mmCIF data structure.
1. IUCrJ - published July 1, 2024
2. Wankowicz SA, Fraser JS
Assembly mechanism of Integrator's RNA cleavage module.
1. Mol Cell - published July 1, 2024
2. Sabath K, Qiu C, Jonas S
LRIG1 controls proliferation of adult neural stem cells by facilitating TGFβ and BMP signalling pathways.
1. Commun Biol - published July 1, 2024
2. Ouzikov S, Edwards KM, Anandampillai T, Watanabe S, Lozano Casasbuenas D, Siu KK, Harkins D, Dou A, Jeong D, Lee JE, Yuzwa SA
HLTF disrupts Cas9-DNA post-cleavage complexes to allow DNA break processing.
1. Nat Commun - published July 1, 2024
2. Reginato G, Dello Stritto MR, Wang Y, Hao J, Pavani R, Schmitz M, Halder S, Morin V, Cannavo E, Ceppi I, Braunshier S, Acharya A, Ropars V, Charbonnier JB, Jinek M, Nussenzweig A, Ha T, Cejka P
Targeting a microbiota Wolbachian aminoacyl-tRNA synthetase to block its pathogenic host.
1. Sci Adv - published July 1, 2024
2. Hoffmann G, Lukarska M, Clare RH, Masters EKG, Johnston KL, Ford L, Turner JD, Ward SA, Taylor MJ, Jensen MR, Palencia A
Targeting soluble amyloid-beta oligomers with a novel nanobody.
1. Sci Rep - published July 1, 2024
2. Haynes JR, Whitmore CA, Behof WJ, Landman CA, Ong HH, Feld AP, Suero IC, Greer CB, Gore JC, Wijesinghe P, Matsubara JA, Wadzinski BE, Spiller BW, Pham W
Phase Separation Modulates the Thermodynamics and Kinetics of RNA Hybridization.
1. J Am Chem Soc - published July 1, 2024
2. Rangadurai AK, Ruetz L, Ahmed R, Lo K, Tollinger M, Forman-Kay JD, Kreutz C, Kay LE
Feedforward cysteine regulation maintains melanoma differentiation state and limits metastatic spread.
1. Cell Rep - published July 1, 2024
2. Yu D, Liang J, Widlund HR, Puigserver P
De novo variants in the RNU4-2 snRNA cause a frequent neurodevelopmental syndrome.
1. Nature - published July 1, 2024
2. Chen Y, Dawes R, Kim HC, Ljungdahl A, Stenton SL, Walker S, Lord J, Lemire G, Martin-Geary AC, Ganesh VS, Ma J, Ellingford JM, Delage E, D'Souza EN, Dong S, Adams DR, Allan K, Bakshi M, Baldwin EE, Berger SI, Bernstein JA, Bhatnagar I, Blair E, Brown NJ, Burrage LC, Chapman K, Coman DJ, Compton AG, Cunningham CA, D'Souza P, Danecek P, Délot EC, Dias KR, Elias ER, Elmslie F, Evans CA, Ewans L, Ezell K, Fraser JL, Gallacher L, Genetti CA, Goriely A, Grant CL, Haack T, Higgs JE, Hinch AG, Hurles ME, Kuechler A, Lachlan KL, Lalani SR, Lecoquierre F, Leitão E, Fevre AL, Leventer RJ, Liebelt JE, Lindsay S, Lockhart PJ, Ma AS, Macnamara EF, Mansour S, Maurer TM, Mendez HR, Metcalfe K, Montgomery SB, Moosajee M, Nassogne MC, Neumann S, O'Donoghue M, O'Leary M, Palmer EE, Pattani N, Phillips J, Pitsava G, Pysar R, Rehm HL, Reuter CM, Revencu N, Riess A, Rius R, Rodan L, Roscioli T, Rosenfeld JA, Sachdev R, Shaw-Smith CJ, Simons C, Sisodiya SM, Snell P, St Clair L, Stark Z, Stewart HS, Tan TY, Tan NB, Temple SEL, Thorburn DR, Tifft CJ, Uebergang E, VanNoy GE, Vasudevan P, Vilain E, Viskochil DH, Wedd L, Wheeler MT, White SM, Wojcik M, Wolfe LA, Wolfenson Z, Wright CF, Xiao C, Zocche D, Rubenstein JL, Markenscoff-Papadimitriou E, Fica SM, Baralle D, Depienne C, MacArthur DG, Howson JMM, Sanders SJ, O'Donnell-Luria A, Whiffin N
Author Correction: A new antibiotic traps lipopolysaccharide in its intermembrane transporter.
1. Nature - published July 1, 2024
2. Pahil KS, Gilman MSA, Baidin V, Clairfeuille T, Mattei P, Bieniossek C, Dey F, Muri D, Baettig R, Lobritz M, Bradley K, Kruse AC, Kahne D
Author Correction: A novel antibiotic class targeting the lipopolysaccharide transporter.
1. Nature - published July 1, 2024
2. Zampaloni C, Mattei P, Bleicher K, Winther L, Thäte C, Bucher C, Adam JM, Alanine A, Amrein KE, Baidin V, Bieniossek C, Bissantz C, Boess F, Cantrill C, Clairfeuille T, Dey F, Di Giorgio P, du Castel P, Dylus D, Dzygiel P, Felici A, García-Alcalde F, Haldimann A, Leipner M, Leyn S, Louvel S, Misson P, Osterman A, Pahil K, Rigo S, Schäublin A, Scharf S, Schmitz P, Stoll T, Trauner A, Zoffmann S, Kahne D, Young JAT, Lobritz MA, Bradley KA
In vitro reconstitution of transition metal transporters.
1. J Biol Chem - published July 1, 2024
2. Ongey EL, Banerjee A