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54 Member Publications for October

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The Neurospora RNA polymerase II kinase CTK negatively regulates Catalase expression in a chromatin context dependent manner.
1. Environ Microbiol - published October 9, 2019
2. Duan J, Liu Q, Su S, Cha J, Zhou Y, Tang R, Liu X, Wang Y, Liu Y, He Q
The Urfold: Structural Similarity Just above the Superfold Level?
1. Protein Sci - published October 9, 2019
2. Mura C, Veretnik S, Bourne PE
Treatment patterns and outcomes in goblet cell carcinoid tumors of the appendix.
1. J Surg Oncol - published October 8, 2019
2. Fields AC, Lu P, Enzinger A, Goldberg J, Irani J, Bleday R, Nash G, Melnitchouk N
Publisher Correction: Ca2+-regulated Ca2+ channels with an RCK gating ring control plant symbiotic associations.
1. Nat Commun - published October 7, 2019
2. Kim S, Zeng W, Bernard S, Liao J, Venkateshwaran M, Ane JM, Jiang Y
Structural pathway for allosteric activation of the autophagic PI 3-kinase complex I.
1. Proc Natl Acad Sci U S A - published October 7, 2019
2. Young LN, Goerdeler F, Hurley JH
High-resolution cryo-EM structures of TFIIH and their functional implications.
1. Curr Opin Struct Biol - published October 7, 2019
2. Nogales E, Greber BJ
An ensemble of flexible conformations underlies mechanotransduction by the cadherin-catenin adhesion complex.
1. Proc Natl Acad Sci U S A - published October 7, 2019
2. Bush M, Alhanshali BM, Qian S, Stanley CB, Heller WT, Matsui T, Weiss TM, Nicholl ID, Walz T, Callaway DJE, Bu Z
Small angle X-ray scattering-assisted protein structure prediction in CASP13 and emergence of solution structure differences.
1. Proteins - published October 7, 2019
2. Hura GL, Hodge CD, Rosenberg D, Guzenko D, Duarte JM, Monastyrskyy B, Grudinin S, Kryshtafovych A, Tainer JA, Fidelis K, Tsutakawa SE
Lipid-targeting pleckstrin homology domain turns its autoinhibitory face toward the TEC kinases.
1. Proc Natl Acad Sci U S A - published October 7, 2019
2. Amatya N, Wales TE, Kwon A, Yeung W, Joseph RE, Fulton DB, Kannan N, Engen JR, Andreotti AH
Identification of an adhesive interface for the non-clustered δ1 protocadherin-1 involved in respiratory diseases.
1. Commun Biol - published October 5, 2019
2. Modak D, Sotomayor M
ADAM proteases: Emerging role and targeting of the non-catalytic domains.
1. Cancer Lett - published October 5, 2019
2. Saha N, Robev D, Himanen JP, Nikolov DB
Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes.
1. Structure - published October 5, 2019
2. Das S, Malaby AW, Nawrotek A, Zhang W, Zeghouf M, Maslen S, Skehel M, Chakravarthy S, Irving TC, Bilsel O, Cherfils J, Lambright DG
Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8+ Lung-Resident Memory T Cells.
1. ACS Nano - published October 4, 2019
2. Knight FC, Gilchuk P, Kumar A, Becker KW, Sevimli S, Jacobson ME, Suryadevara N, Wang-Bishop L, Boyd KL, Crowe JE Jr, Joyce S, Wilson JT
Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases.
1. Science - published October 4, 2019
2. Kondo Y, Ognjenović J, Banerjee S, Karandur D, Merk A, Kulhanek K, Wong K, Roose JP, Subramaniam S, Kuriyan J
Green Synthesis of Substituted Anilines and Quinazolines from Isatoic Anhydride-8-amide.
1. Sci Rep - published October 3, 2019
2. Gondi SR, Bera AK, Westover KD
Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes.
1. Nature - published October 3, 2019
2. Park E, Rawson S, Li K, Kim BW, Ficarro SB, Pino GG, Sharif H, Marto JA, Jeon H, Eck MJ
Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure.
1. Nat Commun - published October 2, 2019
2. Stone NP, Demo G, Agnello E, Kelch BA
Flexibility in nucleic acid binding is central to APOBEC3H antiviral activity.
1. J Virol - published October 2, 2019
2. Bohn JA, DaSilva J, Kharytonchyk S, Mercedes M, Vosters J, Telesnitsky A, Hatziioannou T, Smith JL
FSP1 is a glutathione-independent ferroptosis suppressor.
1. Nature - published October 2, 2019
2. Doll S, Freitas FP, Shah R, Aldrovandi M, da Silva MC, Ingold I, Grocin AG, Xavier da Silva TN, Panzilius E, Scheel C, Mourão A, Buday K, Sato M, Wanninger J, Vignane T, Mohana V, Rehberg M, Flatley A, Schepers A, Kurz A, White D, Sauer M, Sattler M, Tate EW, Schmitz W, Schulze A, O'Donnel V, Proneth B, Popowicz GM, Pratt D, Angeli JPF, Conrad M
How HIV Nef Proteins Hijack Membrane Traffic to Promote Infection.
1. J Virol - published October 2, 2019
2. Buffalo CZ, Iwamoto Y, Hurley JH, Ren X
Structure based inhibitors of Amyloid Beta core suggest a common interface with Tau.
1. Elife - published October 1, 2019
2. Griner SL, Seidler P, Bowler J, Murray KA, Yang TP, Sahay S, Sawaya MR, Cascio D, Rodriguez JA, Philipp S, Sosna J, Glabe CG, Gonen T, Eisenberg DS
The Staphylococcus aureus ArlRS two-component system regulates virulence factor expression through MgrA.
1. Mol Microbiol - published October 1, 2019
2. Crosby HA, Tiwari N, Kwiecinski JM, Xu Z, Dykstra A, Jenul C, Fuentes EJ, Horswill AR
Garcinol and Related Polyisoprenylated Benzophenones as Topoisomerase II Inhibitors: Biochemical and Molecular Modeling Studies.
1. J Nat Prod - published October 1, 2019
2. Di Micco S, Masullo M, Bandak AF, Berger JM, Riccio R, Piacente S, Bifulco G
RNA binding activates RIG-I by releasing an autorepressed signaling domain.
1. Sci Adv - published October 1, 2019
2. Dickey TH, Song B, Pyle AM
MMOD-induced structural changes of hydroxylase in soluble methane monooxygenase.
1. Sci Adv - published October 1, 2019
2. Kim H, An S, Park YR, Jang H, Yoo H, Park SH, Lee SJ, Cho US
HP1 reshapes nucleosome core to promote heterochromatin phase separation.
1. Nature - published October 1, 2019
2. Sanulli S, Trnka MJ, Dharmarajan V, Tibble RW, Pascal BD, Burlingame AL, Griffin PR, Gross JD, Narlikar GJ
Dual Inhibition of TAF1 and BET Bromodomains from the BI-2536 Kinase Inhibitor Scaffold.
1. ACS Med Chem Lett - published October 1, 2019
2. Remillard D, Buckley DL, Seo HS, Ferguson FM, Dhe-Paganon S, Bradner JE, Gray NS
Unique structural features in an Nramp metal transporter impart substrate-specific proton cotransport and a kinetic bias to favor import.
1. J Gen Physiol - published October 1, 2019
2. Bozzi AT, Bane LB, Zimanyi CM, Gaudet R
Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy.
1. Proc Natl Acad Sci U S A - published October 1, 2019
2. Zammataro L, Lopez S, Bellone S, Pettinella F, Bonazzoli E, Perrone E, Zhao S, Menderes G, Altwerger G, Han C, Zeybek B, Bianchi A, Manzano A, Manara P, Cocco E, Buza N, Hui P, Wong S, Ravaggi A, Bignotti E, Romani C, Todeschini P, Zanotti L, Odicino F, Pecorelli S, Donzelli C, Ardighieri L, Angioli R, Raspagliesi F, Scambia G, Choi J, Dong W, Bilguvar K, Alexandrov LB, Silasi DA, Huang GS, Ratner E, Azodi M, Schwartz PE, Pirazzoli V, Stiegler AL, Boggon TJ, Lifton RP, Schlessinger J, Santin AD
Filament-like Assemblies of Intracellular Nucleic Acid Sensors: Commonalities and Differences.
1. Mol Cell - published October 1, 2019
2. Cadena C, Hur S
Properties of Stress Granule and P-Body Proteomes.
1. Mol Cell - published October 1, 2019
2. Youn JY, Dyakov BJA, Zhang J, Knight JDR, Vernon RM, Forman-Kay JD, Gingras AC
Coordination of a single calcium ion in the EF-hand maintains the off state of the stromal interaction molecule luminal domain.
1. J Mol Biol - published October 1, 2019
2. Enomoto M, Nishikawa T, Back SI, Ishiyama N, Zheng L, Stathopulos PB, Ikura M
Computational approaches to therapeutic antibody design: established methods and emerging trends.
1. Brief Bioinform - published October 1, 2019
2. Norman RA, Ambrosetti F, Bonvin AMJJ, Colwell LJ, Kelm S, Kumar S, Krawczyk K
Function and Dysfunction of TMC Channels in Inner Ear Hair Cells.
1. Cold Spring Harb Perspect Med - published October 1, 2019
2. Corey DP, Akyuz N, Holt JR
Structural and Functional Analysis of Ubiquitin-based inhibitors that Target the Backsides of E2 Enzymes.
1. J Mol Biol - published October 1, 2019
2. Garg P, Ceccarelli DF, Keszei AF, Kourinov I, Sicheri F, Sidhu SS
High-Throughput Fluorescence Polarization Assay to Identify Ligands Using Purified G Protein-Coupled Receptor.
1. SLAS Discov - published October 1, 2019
2. Heine P, Witt G, Gilardi A, Gribbon P, Kummer L, Plückthun A
Structural Basis for Diltiazem Block of a Voltage-Gated Ca2+ Channel.
1. Mol Pharmacol - published October 1, 2019
2. Tang L, Gamal El-Din TM, Lenaeus MJ, Zheng N, Catterall WA
Arachidonic Acid Kills Staphylococcus aureus through a Lipid Peroxidation Mechanism.
1. MBio - published October 1, 2019
2. Beavers WN, Monteith AJ, Amarnath V, Mernaugh RL, Roberts LJ 2nd, Chazin WJ, Davies SS, Skaar EP
The NSL complex maintains nuclear architecture stability via lamin A/C acetylation.
1. Nat Cell Biol - published October 1, 2019
2. Karoutas A, Szymanski W, Rausch T, Guhathakurta S, Rog-Zielinska EA, Peyronnet R, Seyfferth J, Chen HR, de Leeuw R, Herquel B, Kimura H, Mittler G, Kohl P, Medalia O, Korbel JO, Akhtar A
Cowpox virus encodes a protein that binds B7.1 and B7.2 and subverts T cell costimulation.
1. Proc Natl Acad Sci U S A - published October 1, 2019
2. Wang X, Piersma SJ, Elliott JI, Errico JM, Gainey MD, Yang L, Nelson CA, Yokoyama WM, Fremont DH
Scribble co-operatively binds multiple α1D-adrenergic receptor C-terminal PDZ ligands.
1. Sci Rep - published October 1, 2019
2. Janezic EM, Harris DA, Dinh D, Lee KS, Stewart A, Hinds TR, Hsu PL, Zheng N, Hague C
The Innate Immune Protein S100A9 Protects from T-Helper Cell Type 2-mediated Allergic Airway Inflammation.
1. Am J Respir Cell Mol Biol - published October 1, 2019
2. Palmer LD, Maloney KN, Boyd KL, Goleniewska AK, Toki S, Maxwell CN, Chazin WJ, Peebles RS Jr, Newcomb DC, Skaar EP
Structure of an RNA helix with pyrimidine mismatches and cross-strand stacking.
1. Acta Crystallogr F Struct Biol Commun - published October 1, 2019
2. Montemayor EJ, Virta JM, Hagler LD, Zimmerman SC, Butcher SE
Cryo-EM of multiple cage architectures reveals a universal mode of clathrin self-assembly.
1. Nat Struct Mol Biol - published October 1, 2019
2. Morris KL, Jones JR, Halebian M, Wu S, Baker M, Armache JP, Avila Ibarra A, Sessions RB, Cameron AD, Cheng Y, Smith CJ
Phosphorylation of Nephrin induces phase separated domains that move through actomyosin contraction.
1. Mol Biol Cell - published October 1, 2019
2. Kim S, Kalappurakkal JM, Mayor S, Rosen MK
Less Is More: Coarse-Grained Integrative Modeling of Large Biomolecular Assemblies with HADDOCK.
1. J Chem Theory Comput - published October 1, 2019
2. Roel-Touris J, Don CG, V Honorato R, Rodrigues JPGLM, Bonvin AMJJ
Intratumoral delivery of RIG-I agonist SLR14 induces robust antitumor responses.
1. J Exp Med - published October 1, 2019
2. Jiang X, Muthusamy V, Fedorova O, Kong Y, Kim DJ, Bosenberg M, Pyle AM, Iwasaki A
Accurate Prediction for Antibody Resistance of Clinical HIV-1 Isolates.
1. Sci Rep - published October 1, 2019
2. Rawi R, Mall R, Shen CH, Farney SK, Shiakolas A, Zhou J, Bensmail H, Chun TW, Doria-Rose NA, Lynch RM, Mascola JR, Kwong PD, Chuang GY
CD23 is a glycan-binding receptor in some mammalian species.
1. J Biol Chem - published October 1, 2019
2. Jégouzo SAF, Feinberg H, Morrison AG, Holder A, May A, Huang Z, Jiang L, Lasanajak Y, Smith DF, Werling D, Drickamer K, Weis WI, Taylor ME
Structure and functional implications of WYL domain-containing bacterial DNA damage response regulator PafBC.
1. Nat Commun - published October 1, 2019
2. Müller AU, Leibundgut M, Ban N, Weber-Ban E
The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
1. EMBO J - published October 1, 2019
2. Acosta-Reyes F, Neupane R, Frank J, Fernández IS
Reinvestigating the synthesis and efficacy of small benzimidazole derivatives as presequence protease enhancers.
1. Eur J Med Chem - published October 1, 2019
2. Li NS, Liang W, Piccirilli JA, Tang WJ
Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination.
1. Nat Immunol - published October 1, 2019
2. Lo WL, Shah NH, Rubin SA, Zhang W, Horkova V, Fallahee IR, Stepanek O, Zon LI, Kuriyan J, Weiss A
KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis.
1. Proc Natl Acad Sci U S A - published October 1, 2019
2. Rabara D, Tran TH, Dharmaiah S, Stephens RM, McCormick F, Simanshu DK, Holderfield M