Member Publications

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139 Member Publications for November 2016

In Vitro Assays to Identify Antibiotics Targeting DNA Metabolism.
1. Methods Mol Biol - published November 23, 2016
2. Pang AH, Garneau-Tsodikova S, Tsodikov OV
Understanding the Structural Basis of Adhesion GPCR Functions.
1. Handb Exp Pharmacol - published November 11, 2016
2. Araç D, Sträter N, Seiradake E
Evaluation of the Nucleolar Localization of the RENT Complex to Ribosomal DNA by Chromatin Immunoprecipitation Assays.
1. Methods Mol Biol - published November 10, 2016
2. Huang J, Iglesias N, Moazed D
Structural and mechanistic insights into regulation of the retromer coat by TBC1d5.
1. Nat Commun - published November 9, 2016
2. Jia D, Zhang JS, Li F, Wang J, Deng Z, White MA, Osborne DG, Phillips-Krawczak C, Gomez TS, Li H, Singla A, Burstein E, Billadeau DD, Rosen MK
Structural Analysis of the Bacterial Proteasome Activator Bpa in Complex with the 20S Proteasome.
1. Structure - published November 9, 2016
2. Bolten M, Delley CL, Leibundgut M, Boehringer D, Ban N, Weber-Ban E
Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth.
1. Mol Cell - published November 9, 2016
2. Fan J, Lin R, Xia S, Chen D, Elf SE, Liu S, Pan Y, Xu H, Qian Z, Wang M, Shan C, Zhou L, Lei QY, Li Y, Mao H, Lee BH, Sudderth J, DeBerardinis RJ, Zhang G, Owonikoko T, Gaddh M, Arellano ML, Khoury HJ, Khuri FR, Kang S, Doetsch PW, Lonial S, Boggon TJ, Curran WJ, Chen J
Crystal Structure of Os79 (Os04g0206600) from Oryza sativa: A UDP-glucosyltransferase Involved in the Detoxification of Deoxynivalenol.
1. Biochemistry - published November 8, 2016
2. Wetterhorn KM, Newmister SA, Caniza RK, Busman M, McCormick SP, Berthiller F, Adam G, Rayment I
Acid activation mechanism of the influenza A M2 proton channel.
1. Proc Natl Acad Sci U S A - published November 8, 2016
2. Liang R, Swanson JMJ, Madsen JJ, Hong M, DeGrado WF, Voth GA
The Outer Pore and Selectivity Filter of TRPA1.
1. PLoS One - published November 8, 2016
2. Christensen AP, Akyuz N, Corey DP
A Regulatory Switch Alters Chromosome Motions at the Metaphase-to-Anaphase Transition.
1. Cell Rep - published November 8, 2016
2. Su KC, Barry Z, Schweizer N, Maiato H, Bathe M, Cheeseman IM
Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice.
1. Nature - published November 7, 2016
2. Sapparapu G, Fernandez E, Kose N, Cao B, Fox JM, Bombardi RG, Zhao H, Nelson CA, Bryan AL, Barnes T, Davidson E, Mysorekar IU, Fremont DH, Doranz BJ, Diamond MS, Crowe JE
Inhibition of RAS function through targeting an allosteric regulatory site.
1. Nat Chem Biol - published November 7, 2016
2. Spencer-Smith R, Koide A, Zhou Y, Eguchi RR, Sha F, Gajwani P, Santana D, Gupta A, Jacobs M, Herrero-Garcia E, Cobbert J, Lavoie H, Smith M, Rajakulendran T, Dowdell E, Okur MN, Dementieva I, Sicheri F, Therrien M, Hancock JF, Ikura M, Koide S, O'Bryan JP
Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF.
1. Nat Commun - published November 7, 2016
2. Felix J, Kandiah E, De Munck S, Bloch Y, van Zundert GC, Pauwels K, Dansercoer A, Novanska K, Read RJ, Bonvin AM, Vergauwen B, Verstraete K, Gutsche I, Savvides SN
Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
1. Nat Med - published November 7, 2016
2. Raymond DD, Stewart SM, Lee J, Ferdman J, Bajic G, Do KT, Ernandes MJ, Suphaphiphat P, Settembre EC, Dormitzer PR, Del Giudice G, Finco O, Kang TH, Ippolito GC, Georgiou G, Kepler TB, Haynes BF, Moody MA, Liao HX, Schmidt AG, Harrison SC
Ligand-induced and small-molecule control of substrate loading in a hexameric helicase.
1. Proc Natl Acad Sci U S A - published November 7, 2016
2. Lawson MR, Dyer K, Berger JM
C-terminal domain of mammalian complexin-1 localizes to highly curved membranes.
1. Proc Natl Acad Sci U S A - published November 7, 2016
2. Gong J, Lai Y, Li X, Wang M, Leitz J, Hu Y, Zhang Y, Choi UB, Cipriano D, Pfuetzner RA, Südhof TC, Yang X, Brunger AT, Diao J
General Anesthetic Binding Sites in Human α4β3δ γ-Aminobutyric Acid Type-A Receptors (GABAAR).
1. J Biol Chem - published November 7, 2016
2. Chiara DC, Jounaidi Y, Zhou X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB
Differential Penicillin-Binding Protein 5 (PBP5) Levels in the Enterococcus faecium Clades with Different Levels of Ampicillin Resistance.
1. Antimicrob Agents Chemother - published November 7, 2016
2. Montealegre MC, Roh JH, Rae M, Davlieva MG, Singh KV, Shamoo Y, Murray BE
Distinct regions that control ion selectivity and calcium-dependent activation in the bestrophin ion channel.
1. Proc Natl Acad Sci U S A - published November 7, 2016
2. Vaisey G, Miller AN, Long SB
Structure of the transmembrane domain of HIV-1 envelope glycoprotein.
1. FEBS J - published November 5, 2016
2. Chen B, Chou JJ
O6-2'-Deoxyguanosine-butylene-O6-2'-deoxyguanosine DNA Interstrand Cross-Links Are Replication-Blocking and Mutagenic DNA Lesions.
1. Chem Res Toxicol - published November 4, 2016
2. Xu W, Kool D, O'Flaherty DK, Keating AM, Sacre L, Egli M, Noronha A, Wilds CJ, Zhao L
Complete structure of the bacterial flagellar hook reveals extensive set of stabilizing interactions.
1. Nat Commun - published November 4, 2016
2. Matsunami H, Barker CS, Yoon YH, Wolf M, Samatey FA
Enhancing Self-Efficacy for Help-Seeking Among Transition-Aged Youth in Postsecondary Settings With Mental Health and/or Substance Use Concerns, Using Crowd-Sourced Online and Mobile Technologies: The Thought Spot Protocol.
1. JMIR Res Protoc - published November 4, 2016
2. Wiljer D, Abi-Jaoude A, Johnson A, Ferguson G, Sanches M, Levinson A, Robb J, Heffernan O, Herzog T, Chaim G, Cleverley K, Eysenbach G, Henderson J, S Hoch J, Hollenberg E, Jiang H, Isaranuwatchai W, Law M, Sharpe S, Tripp T, Voineskos A
Regulation of KCNQ/Kv7 family voltage-gated K+ channels by lipids.
1. Biochim Biophys Acta - published November 4, 2016
2. Taylor KC, Sanders CR
Biallelic Mutations in TMTC3, Encoding a Transmembrane and TPR-Containing Protein, Lead to Cobblestone Lissencephaly.
1. Am J Hum Genet - published November 3, 2016
2. Jerber J, Zaki MS, Al-Aama JY, Rosti RO, Ben-Omran T, Dikoglu E, Silhavy JL, Caglar C, Musaev D, Albrecht B, Campbell KP, Willer T, Almuriekhi M, Çağlayan AO, Vajsar J, Bilgüvar K, Ogur G, Abou Jamra R, Günel M, Gleeson JG
Tail and Kinase Modules Differently Regulate Core Mediator Recruitment and Function In Vivo.
1. Mol Cell - published November 3, 2016
2. Jeronimo C, Langelier MF, Bataille AR, Pascal JM, Pugh BF, Robert F
Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket.
1. Cell - published November 3, 2016
2. Zimmerman B, Kelly B, McMillan BJ, Seegar TC, Dror RO, Kruse AC, Blacklow SC
Structure of the MIND Complex Defines a Regulatory Focus for Yeast Kinetochore Assembly.
1. Cell - published November 3, 2016
2. Dimitrova YN, Jenni S, Valverde R, Khin Y, Harrison SC
Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores.
1. Cell - published November 3, 2016
2. Petrovic A, Keller J, Liu Y, Overlack K, John J, Dimitrova YN, Jenni S, van Gerwen S, Stege P, Wohlgemuth S, Rombaut P, Herzog F, Harrison SC, Vetter IR, Musacchio A
Membrane Core-Specific Antimicrobial Action of Cathelicidin LL-37 Peptide Switches Between Pore and Nanofibre Formation.
1. Sci Rep - published November 3, 2016
2. Shahmiri M, Enciso M, Adda CG, Smith BJ, Perugini MA, Mechler A
Structural basis for the disaggregase activity and regulation of Hsp104.
1. Elife - published November 3, 2016
2. Heuck A, Schitter-Sollner S, Suskiewicz MJ, Kurzbauer R, Kley J, Schleiffer A, Rombaut P, Herzog F, Clausen T
Structural Basis for the KlenTaq DNA Polymerase Catalysed Incorporation of Alkene- versus Alkyne-Modified Nucleotides.
1. Chemistry - published November 3, 2016
2. Hottin A, Betz K, Diederichs K, Marx A
Structure and mechanism of NOV1, a resveratrol-cleaving dioxygenase.
1. Proc Natl Acad Sci U S A - published November 3, 2016
2. McAndrew RP, Sathitsuksanoh N, Mbughuni MM, Heins RA, Pereira JH, George A, Sale KL, Fox BG, Simmons BA, Adams PD
Discoidin domain receptor 1 kinase activity is required for regulating collagen IV synthesis.
1. Matrix Biol - published November 3, 2016
2. Borza CM, Su Y, Tran TL, Yu L, Steyns N, Temple KJ, Skwark MJ, Meiler J, Lindsley CW, Hicks BR, Leitinger B, Zent R, Pozzi A
Covalent Guanosine Mimetic Inhibitors of G12C KRAS.
1. ACS Med Chem Lett - published November 3, 2016
2. Xiong Y, Lu J, Hunter J, Li L, Scott D, Choi HG, Lim SM, Manandhar A, Gondi S, Sim T, Westover KD, Gray NS
Relationships of human α/β hydrolase fold proteins and other organophosphate-interacting proteins.
1. Chem Biol Interact - published November 2, 2016
2. Lenfant N, Bourne Y, Marchot P, Chatonnet A
A Golgi rhomboid protease Rbd2 recruits Cdc48 to cleave yeast SREBP.
1. EMBO J - published November 2, 2016
2. Hwang J, Ribbens D, Raychaudhuri S, Cairns L, Gu H, Frost A, Urban S, Espenshade PJ
Structural Dynamics in Ras and Related Proteins upon Nucleotide Switching.
1. J Mol Biol - published November 2, 2016
2. Harrison RA, Lu J, Carrasco M, Hunter J, Manandhar A, Gondi S, Westover KD, Engen JR
Rational Design of Cyclic Peptide Inhibitors of U2AF Homology Motif (UHM) Domains To Modulate Pre-mRNA Splicing.
1. J Med Chem - published November 2, 2016
2. Jagtap PK, Garg D, Kapp TG, Will CL, Demmer O, Lührmann R, Kessler H, Sattler M
Engineering and optimising deaminase fusions for genome editing.
1. Nat Commun - published November 2, 2016
2. Yang L, Briggs AW, Chew WL, Mali P, Guell M, Aach J, Goodman DB, Cox D, Kan Y, Lesha E, Soundararajan V, Zhang F, Church G
Identification of DNA primase inhibitors via a combined fragment-based and virtual screening.
1. Sci Rep - published November 2, 2016
2. Ilic S, Akabayov SR, Arthanari H, Wagner G, Richardson CC, Akabayov B
Key Intermediates in Ribosome Recycling Visualized by Time-Resolved Cryoelectron Microscopy.
1. Structure - published November 2, 2016
2. Fu Z, Kaledhonkar S, Borg A, Sun M, Chen B, Grassucci RA, Ehrenberg M, Frank J
Defining NADH-Driven Allostery Regulating Apoptosis-Inducing Factor.
1. Structure - published November 2, 2016
2. Brosey CA, Ho C, Long WZ, Singh S, Burnett K, Hura GL, Nix JC, Bowman GR, Ellenberger T, Tainer JA
Tet2 and Tet3 cooperate with B-lineage transcription factors to regulate DNA modification and chromatin accessibility.
1. Elife - published November 2, 2016
2. Lio CJ, Zhang J, González-Avalos E, Hogan PG, Chang X, Rao A
Structure of photosystem II and substrate binding at room temperature.
1. Nature - published November 2, 2016
2. Young ID, Ibrahim M, Chatterjee R, Gul S, Fuller FD, Koroidov S, Brewster AS, Tran R, Alonso-Mori R, Kroll T, Michels-Clark T, Laksmono H, Sierra RG, Stan CA, Hussein R, Zhang M, Douthit L, Kubin M, de Lichtenberg C, Vo Pham L, Nilsson H, Cheah MH, Shevela D, Saracini C, Bean MA, Seuffert I, Sokaras D, Weng TC, Pastor E, Weninger C, Fransson T, Lassalle L, Bräuer P, Aller P, Docker PT, Andi B, Orville AM, Glownia JM, Nelson S, Sikorski M, Zhu D, Hunter MS, Lane TJ, Aquila A, Koglin JE, Robinson J, Liang M, Boutet S, Lyubimov AY, Uervirojnangkoorn M, Moriarty NW, Liebschner D, Afonine PV, Waterman DG, Evans G, Wernet P, Dobbek H, Weis WI, Brunger AT, Zwart PH, Adams PD, Zouni A, Messinger J, Bergmann U, Sauter NK, Kern J, Yachandra VK, Yano J
Covalently circularized nanodiscs for studying membrane proteins and viral entry.
1. Nat Methods - published November 2, 2016
2. Nasr ML, Baptista D, Strauss M, Sun ZJ, Grigoriu S, Huser S, Plückthun A, Hagn F, Walz T, Hogle JM, Wagner G
Lyme disease spirochaete Borrelia burgdorferi does not require thiamin.
1. Nat Microbiol - published November 2, 2016
2. Zhang K, Bian J, Deng Y, Smith A, Nunez RE, Li MB, Pal U, Yu AM, Qiu W, Ealick SE, Li C
Actin is an evolutionarily-conserved damage-associated molecular pattern that signals tissue injury in Drosophila melanogaster.
1. Elife - published November 2, 2016
2. Srinivasan N, Gordon O, Ahrens S, Franz A, Deddouche S, Chakravarty P, Phillips D, Yunus AA, Rosen MK, Valente RS, Teixeira L, Thompson B, Dionne MS, Wood W, Reis E Sousa C
Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine.
1. J Biol Chem - published November 2, 2016
2. Harshbarger W, Gondi S, Ficarro SB, Hunter J, Udayakumar D, Gurbani D, Singer W, Liu Y, Li L, Marto JA, Westover KD
Sortase A-Generated Highly Potent Anti-CD20-MMAE Conjugates for Efficient Elimination of B-Lineage Lymphomas.
1. Small - published November 2, 2016
2. Pan L, Zhao W, Lai J, Ding D, Zhang Q, Yang X, Huang M, Jin S, Xu Y, Zeng S, Chou JJ, Chen S
The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.
1. J Cell Biol - published November 2, 2016
2. Scharaw S, Iskar M, Ori A, Boncompain G, Laketa V, Poser I, Lundberg E, Perez F, Beck M, Bork P, Pepperkok R
GTPase cross talk regulates TRAPPII activation of Rab11 homologues during vesicle biogenesis.
1. J Cell Biol - published November 2, 2016
2. Thomas LL, Fromme JC
A Deep Hydrophobic Binding Cavity is the Main Interaction for Different Y2 R Antagonists.
1. ChemMedChem - published November 2, 2016
2. Burkert K, Zellmann T, Meier R, Kaiser A, Stichel J, Meiler J, Mittapalli GK, Roberts E, Beck-Sickinger AG
Structure of protein O-mannose kinase reveals a unique active site architecture.
1. Elife - published November 2, 2016
2. Zhu Q, Venzke D, Walimbe AS, Anderson ME, Fu Q, Kinch LN, Wang W, Chen X, Grishin NV, Huang N, Yu L, Dixon JE, Campbell KP, Xiao J
Molecular determinants of KA1 domain-mediated autoinhibition and phospholipid activation of MARK1 kinase.
1. Biochem J - published November 2, 2016
2. Emptage RP, Lemmon MA, Ferguson KM
Discovery and Biological Characterization of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors.
1. FEBS Lett - published November 2, 2016
2. Lee T, Bian Z, Zhao B, Hogdal LJ, Sensintaffar JL, Goodwin CM, Belmar J, Shaw S, Tarr JC, Veerasamy N, Matulis SM, Koss B, Fischer MA, Arnold AL, Camper DV, Browning CF, Rossanese OW, Budhraja A, Opferman J, Boise LH, Savona MR, Letai A, Olejniczak ET, Fesik SW
Characterization of two distinct early post-entry blocks to HIV-1 in common marmoset lymphocytes.
1. Sci Rep - published November 2, 2016
2. Pacheco B, Menéndez-Arias L, Sodroski J
Clustering of disulfide-rich peptides provides scaffolds for hit discovery by phage display: application to interleukin-23.
1. BMC Bioinformatics - published November 2, 2016
2. Barkan DT, Cheng XL, Celino H, Tran TT, Bhandari A, Craik CS, Sali A, Smythe ML
Activation and Inactivation of Primary Human Immunodeficiency Virus (HIV-1) Envelope Glycoprotein Trimers by CD4-Mimetic Compounds.
1. J Virol - published November 2, 2016
2. Madani N, Princiotto AM, Zhao C, Jahanbakhshsefidi F, Mertens M, Herschhorn A, Melillo B, Smith AB 3rd, Sodroski J
BAG3 is a modular, scaffolding protein that physically links heat shock protein 70 (Hsp70) to the small heat shock proteins.
1. J Mol Biol - published November 2, 2016
2. Rauch JN, Tse E, Freilich R, Mok SA, Makley LN, Southworth DR, Gestwicki JE
Selective Targeting of High-Affinity LFA-1 Does Not Augment Costimulation Blockade in a Nonhuman Primate Renal Transplantation Model.
1. Am J Transplant - published November 2, 2016
2. Samy KP, Anderson DA, Lo DJ, Mulvihill MS, Song M, Farris AB, Parker BS, MacDonald AL, Lu C, Springer TA, Kachlany SC, Reimann KA, How T, Leopardi FV, Franke KS, Williams KD, Collins BH, Kirk AD
Novel Functional Properties of Drosophila CNS Glutamate Receptors.
1. Neuron - published November 2, 2016
2. Li Y, Dharkar P, Han TH, Serpe M, Lee CH, Mayer ML
A mouse model for MERS coronavirus-induced acute respiratory distress syndrome.
1. Nat Microbiol - published November 2, 2016
2. Cockrell AS, Yount BL, Scobey T, Jensen K, Douglas M, Beall A, Tang XC, Marasco WA, Heise MT, Baric RS
The AP-1 transcription factor JunB is essential for multiple myeloma cell proliferation and drug resistance in the bone marrow microenvironment.
1. Leukemia - published November 2, 2016
2. Fan F, Bashari MH, Morelli E, Tonon G, Malvestiti S, Vallet S, Jarahian M, Seckinger A, Hose D, Bakiri L, Sun C, Hu Y, Ball CR, Glimm H, Sattler M, Goldschmidt H, Wagner EF, Tassone P, Jaeger D, Podar K
Direct visualization of a Fe(IV)-OH intermediate in a heme enzyme.
1. Nat Commun - published November 2, 2016
2. Kwon H, Basran J, Casadei CM, Fielding AJ, Schrader TE, Ostermann A, Devos JM, Aller P, Blakeley MP, Moody PCE, Raven EL
Structural basis for the recognition of spliceosomal SmN/B/B' proteins by the RBM5 OCRE domain in splicing regulation.
1. Elife - published November 2, 2016
2. Mourão A, Bonnal S, Soni K, Warner L, Bordonné R, Valcárcel J, Sattler M
Prevention of Vγ9Vδ2 T Cell Activation by a Vγ9Vδ2 TCR Nanobody.
1. J Immunol - published November 2, 2016
2. de Bruin RC, Stam AG, Vangone A, van Bergen En Henegouwen PM, Verheul HM, Sebestyén Z, Kuball J, Bonvin AM, de Gruijl TD, van der Vliet HJ
Astragalus polysaccharide restores autophagic flux and improves cardiomyocyte function in doxorubicin-induced cardiotoxicity.
1. Oncotarget - published November 2, 2016
2. Cao Y, Shen T, Huang X, Lin Y, Chen B, Pang J, Li G, Wang Q, Zohrabian S, Duan C, Ruan Y, Man Y, Wang S, Li J
The Rrp6 C-terminal domain binds RNA and activates the nuclear RNA exosome.
1. Nucleic Acids Res - published November 2, 2016
2. Wasmuth EV, Lima CD
siRNA carrying an (E)-vinylphosphonate moiety at the 5' end of the guide strand augments gene silencing by enhanced binding to human Argonaute-2.
1. Nucleic Acids Res - published November 2, 2016
2. Elkayam E, Parmar R, Brown CR, Willoughby JL, Theile CS, Manoharan M, Joshua-Tor L
Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7.
1. Nucleic Acids Res - published November 2, 2016
2. Wan LC, Maisonneuve P, Szilard RK, Lambert JP, Ng TF, Manczyk N, Huang H, Laister R, Caudy AA, Gingras AC, Durocher D, Sicheri F
Breast cancer-derived extracellular vesicles stimulate myofibroblast differentiation and pro-angiogenic behavior of adipose stem cells.
1. Matrix Biol - published November 2, 2016
2. Song YH, Warncke C, Choi SJ, Choi S, Chiou AE, Ling L, Liu HY, Daniel S, Antonyak MA, Cerione RA, Fischbach C
Store operated calcium entry: From concept to structural mechanisms.
1. Cell Calcium - published November 2, 2016
2. Stathopulos PB, Ikura M
Synchrotron-based macromolecular crystallography module for an undergraduate biochemistry laboratory course.
1. J Appl Crystallogr - published November 2, 2016
2. Stiers KM, Lee CB, Nix JC, Tanner JJ, Beamer LJ
ContaMiner and ContaBase: a webserver and database for early identification of unwantedly crystallized protein contaminants.
1. J Appl Crystallogr - published November 2, 2016
2. Hungler A, Momin A, Diederichs K, Arold ST
A unified molecular mechanism for the regulation of acetyl-CoA carboxylase by phosphorylation.
1. Cell Discov - published November 2, 2016
2. Wei J, Zhang Y, Yu TY, Sadre-Bazzaz K, Rudolph MJ, Amodeo GA, Symington LS, Walz T, Tong L
A Versatile System for High-Throughput In Situ X-ray Screening and Data Collection of Soluble and Membrane-Protein Crystals.
1. Cryst Growth Des - published November 2, 2016
2. Broecker J, Klingel V, Ou WL, Balo AR, Kissick DJ, Ogata CM, Kuo A, Ernst OP
Next generation sequencing yields the complete mitochondrial genome of the Zebra moray, Gymnomuraena zebra (Anguilliformes: Muraenidae).
1. Mitochondrial DNA A DNA Mapp Seq Anal - published November 1, 2016
2. Loh KH, Shao KT, Chen HM, Chen CH, Chong VC, Loo PL, Shen KN, Hsiao CD
Phylogenomic analysis of Candidatus 'Izimaplasma' species: free-living representatives from a Tenericutes clade found in methane seeps.
1. ISME J - published November 1, 2016
2. Skennerton CT, Haroon MF, Briegel A, Shi J, Jensen GJ, Tyson GW, Orphan VJ
Binding properties of YjeQ (RsgA), RbfA, RimM and Era to assembly intermediates of the 30S subunit.
1. Nucleic Acids Res - published November 1, 2016
2. Thurlow B, Davis JH, Leong V, Moraes TF, Williamson JR, Ortega J
A parallel panning scheme used for selection of a GluA4-specific Fab targeting the ligand-binding domain.
1. Int J Biol Macromol - published November 1, 2016
2. Clausen RP, Mohr AØ, Riise E, Jensen AA, Gill A, Madden DR, Kastrup JS, Skottrup PD
Remote Ischemic Preconditioning: A Novel Strategy in Rescuing Older Livers From Ischemia-reperfusion Injury in a Rodent Model.
1. Ann Surg - published November 1, 2016
2. Limani P, Linecker M, Oberkofler CE, Barmettler G, Kaech A, Graf R, Humar B, Clavien PA
Surface plasmon resonance and isothermal titration calorimetry to monitor the Ni(II)-dependent binding of Helicobacter pylori NikR to DNA.
1. Anal Bioanal Chem - published November 1, 2016
2. Fabini E, Zambelli B, Mazzei L, Ciurli S, Bertucci C
Patterning of papillae on the mouse tongue: A system for the quantitative assessment of planar cell polarity signaling.
1. Dev Biol - published November 1, 2016
2. Wang Y, Williams J, Rattner A, Wu S, Bassuk AG, Goffinet AM, Nathans J
Noncovalent Ubiquitin Interactions Regulate the Catalytic Activity of Ubiquitin Writers.
1. Trends Biochem Sci - published November 1, 2016
2. Wright JD, Mace PD, Day CL
Synthesis of (benzimidazol-2-yl)aniline derivatives as glycogen phosphorylase inhibitors.
1. Bioorg Med Chem - published November 1, 2016
2. Galal SA, Khattab M, Andreadaki F, Chrysina ED, Praly JP, Ragab FAF, El Diwani HI
The Preserved HTH-Docking Cleft of HIV-1 Integrase Is Functionally Critical.
1. Structure - published November 1, 2016
2. Galilee M, Britan-Rosich E, Griner SL, Uysal S, Baumgärtel V, Lamb DC, Kossiakoff AA, Kotler M, Stroud RM, Marx A, Alian A
An interaction between Scribble and the NADPH oxidase complex controls M1 macrophage polarization and function.
1. Nat Cell Biol - published November 1, 2016
2. Zheng W, Umitsu M, Jagan I, Tran CW, Ishiyama N, BeGora M, Araki K, Ohashi PS, Ikura M, Muthuswamy SK
ETAA1 acts at stalled replication forks to maintain genome integrity.
1. Nat Cell Biol - published November 1, 2016
2. Bass TE, Luzwick JW, Kavanaugh G, Carroll C, Dungrawala H, Glick GG, Feldkamp MD, Putney R, Chazin WJ, Cortez D
Derivatives of 3-Amino-2-methylpyridine as BAZ2B Bromodomain Ligands: In Silico Discovery and in Crystallo Validation.
1. J Med Chem - published November 1, 2016
2. Marchand JR, Lolli G, Caflisch A
Design of Selective Substrates and Activity-Based Probes for Hydrolase Important for Pathogenesis 1 (HIP1) from Mycobacterium tuberculosis.
1. ACS Infect Dis - published November 1, 2016
2. Lentz CS, Ordonez AA, Kasperkiewicz P, La Greca F, O'Donoghue AJ, Schulze CJ, Powers JC, Craik CS, Drag M, Jain SK, Bogyo M
Solution NMR structure of the HLTF HIRAN domain: a conserved module in SWI2/SNF2 DNA damage tolerance proteins.
1. J Biomol NMR - published November 1, 2016
2. Korzhnev DM, Neculai D, Dhe-Paganon S, Arrowsmith CH, Bezsonova I
Biochemical and Functional Assays of Human Cohesin-Releasing Factor Wapl.
1. Methods Mol Biol - published November 1, 2016
2. Zheng G, Ouyang Z, Yu H
Dear microtubule, I see you.
1. Mol Biol Cell - published November 1, 2016
2. Nogales E
Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop.
1. Proc Natl Acad Sci U S A - published November 1, 2016
2. Wang H, Cohen AA, Galimidi RP, Gristick HB, Jensen GJ, Bjorkman PJ
Recognition of the 3' splice site RNA by the U2AF heterodimer involves a dynamic population shift.
1. Proc Natl Acad Sci U S A - published November 1, 2016
2. Voith von Voithenberg L, Sánchez-Rico C, Kang HS, Madl T, Zanier K, Barth A, Warner LR, Sattler M, Lamb DC
Sense and simplicity in HADDOCK scoring: Lessons from CASP-CAPRI round 1.
1. Proteins - published November 1, 2016
2. Vangone A, Rodrigues JP, Xue LC, van Zundert GC, Geng C, Kurkcuoglu Z, Nellen M, Narasimhan S, Karaca E, van Dijk M, Melquiond AS, Visscher KM, Trellet M, Kastritis PL, Bonvin AM
Independent activation of ion conduction pores in the double-barreled calcium-activated chloride channel TMEM16A.
1. J Gen Physiol - published November 1, 2016
2. Lim NK, Lam AK, Dutzler R
The ATPase Motor Turns for Type IV Pilus Assembly.
1. Structure - published November 1, 2016
2. Tsai CL, Tainer JA
Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein.
1. Proc Natl Acad Sci U S A - published November 1, 2016
2. Mousa JJ, Sauer MF, Sevy AM, Finn JA, Bates JT, Alvarado G, King HG, Loerinc LB, Fong RH, Doranz BJ, Correia BE, Kalyuzhniy O, Wen X, Jardetzky TS, Schief WR, Ohi MD, Meiler J, Crowe JE Jr
Crystal structure of the cohesin loader Scc2 and insight into cohesinopathy.
1. Proc Natl Acad Sci U S A - published November 1, 2016
2. Kikuchi S, Borek DM, Otwinowski Z, Tomchick DR, Yu H
Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ.
1. Proc Natl Acad Sci U S A - published November 1, 2016
2. Dharmaiah S, Bindu L, Tran TH, Gillette WK, Frank PH, Ghirlando R, Nissley DV, Esposito D, McCormick F, Stephen AG, Simanshu DK
Bacterial Energy Sensor Aer Modulates the Activity of the Chemotaxis Kinase CheA Based on the Redox State of the Flavin Cofactor.
1. J Biol Chem - published November 1, 2016
2. Samanta D, Widom J, Borbat PP, Freed JH, Crane BR
Structural elements of an NRPS cyclization domain and its intermodule docking domain.
1. Proc Natl Acad Sci U S A - published November 1, 2016
2. Dowling DP, Kung Y, Croft AK, Taghizadeh K, Kelly WL, Walsh CT, Drennan CL
OCULAR HYPERTENSION AFTER INTRAVITREAL DEXAMETHASONE (OZURDEX) SUSTAINED-RELEASE IMPLANT.
1. Retina - published November 1, 2016
2. Chin EK, Almeida DR, Velez G, Xu K, Peraire M, Corbella M, Elshatory YM, Kwon YH, Gehrs KM, Boldt HC, Sohn EH, Russell SR, Folk JC, Mahajan VB
Role of CBS and Bateman Domains in Phosphorylation-Dependent Regulation of a CLC Anion Channel.
1. Biophys J - published November 1, 2016
2. Yamada T, Krzeminski M, Bozoky Z, Forman-Kay JD, Strange K
Backbone resonance assignments of the F-actin binding domain of mouse αN-catenin.
1. Biomol NMR Assign - published November 1, 2016
2. Nishikawa T, Ishiyama N, Wang F, Ikura M
Molecular lock regulates binding of glycine to a primitive NMDA receptor.
1. Proc Natl Acad Sci U S A - published November 1, 2016
2. Yu A, Alberstein R, Thomas A, Zimmet A, Grey R, Mayer ML, Lau AY
Scramblase TMEM16F terminates T cell receptor signaling to restrict T cell exhaustion.
1. J Exp Med - published November 1, 2016
2. Hu Y, Kim JH, He K, Wan Q, Kim J, Flach M, Kirchhausen T, Vortkamp A, Winau F
Discrete TCR Binding Kinetics Control Invariant NKT Cell Selection and Central Priming.
1. J Immunol - published November 1, 2016
2. Cruz Tleugabulova M, Escalante NK, Deng S, Fieve S, Ereño-Orbea J, Savage PB, Julien JP, Mallevaey T
Nuclear RNA Exosome at 3.1 Å Reveals Substrate Specificities, RNA Paths, and Allosteric Inhibition of Rrp44/Dis3.
1. Mol Cell - published November 1, 2016
2. Zinder JC, Wasmuth EV, Lima CD
Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue Glt_Tk.
1. Nat Commun - published November 1, 2016
2. Guskov A, Jensen S, Faustino I, Marrink SJ, Slotboom DJ
Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
1. Acta Crystallogr F Struct Biol Commun - published November 1, 2016
2. Bzymek KP, Avery KA, Ma Y, Horne DA, Williams JC
Heterochromatin assembly by interrupted Sir3 bridges across neighboring nucleosomes.
1. Elife - published November 1, 2016
2. Behrouzi R, Lu C, Currie MA, Jih G, Iglesias N, Moazed D
Structure and Function of the Nuclear Pore Complex Cytoplasmic mRNA Export Platform.
1. Cell - published November 1, 2016
2. Fernandez-Martinez J, Kim SJ, Shi Y, Upla P, Pellarin R, Gagnon M, Chemmama IE, Wang J, Nudelman I, Zhang W, Williams R, Rice WJ, Stokes DL, Zenklusen D, Chait BT, Sali A, Rout MP
Inhibition of JCPyV infection mediated by targeted viral genome editing using CRISPR/Cas9.
1. Sci Rep - published November 1, 2016
2. Chou YY, Krupp A, Kaynor C, Gaudin R, Ma M, Cahir-McFarland E, Kirchhausen T
Pulmonary Vasculopathy Associated with FIGF Gene Mutation.
1. Am J Pathol - published November 1, 2016
2. Bailey E, Cui Y, Casey A, Stoler JM, Ai X, Ma D, Handin R, Sliz P, Vargas SO, El-Chemaly SY
Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.
1. Immunity - published November 1, 2016
2. Huang J, Kang BH, Ishida E, Zhou T, Griesman T, Sheng Z, Wu F, Doria-Rose NA, Zhang B, McKee K, O'Dell S, Chuang GY, Druz A, Georgiev IS, Schramm CA, Zheng A, Joyce MG, Asokan M, Ransier A, Darko S, Migueles SA, Bailer RT, Louder MK, Alam SM, Parks R, Kelsoe G, Von Holle T, Haynes BF, Douek DC, Hirsch V, Seaman MS, Shapiro L, Mascola JR, Kwong PD, Connors M
DNA polymerase ζ limits chromosomal damage and promotes cell survival following aflatoxin exposure.
1. Proc Natl Acad Sci U S A - published November 1, 2016
2. Lin YC, Owen N, Minko IG, Lange SS, Li L, Stone MP, Wood RD, McCullough AK, Lloyd RS
An HD domain phosphohydrolase active site tailored for oxetanocin-A biosynthesis.
1. Proc Natl Acad Sci U S A - published November 1, 2016
2. Bridwell-Rabb J, Kang G, Zhong A, Liu HW, Drennan CL
High-resolution crystal structure of the human CB1 cannabinoid receptor.
1. Nature - published November 1, 2016
2. Shao Z, Yin J, Chapman K, Grzemska M, Clark L, Wang J, Rosenbaum DM
Conserved Tetramer Junction in the Kinetochore Ndc80 Complex.
1. Cell Rep - published November 1, 2016
2. Valverde R, Ingram J, Harrison SC
CryoEM structures of expanded poliovirus with VHHs sample the conformational repertoire of the expanded state.
1. J Virol - published November 1, 2016
2. Strauss M, Schotte L, Karunatilaka KS, Filman DJ, Hogle JM
Memory Upgrade: Insights into Primed Adaptation by CRISPR-Cas Immune Systems.
1. Mol Cell - published November 1, 2016
2. Ramachandran A, Bailey S
Molecular Mechanism of Action of Antimalarial Benzoisothiazolones: Species-Selective Inhibitors of the Plasmodium spp. MEP Pathway enzyme, IspD.
1. Sci Rep - published November 1, 2016
2. Price KE, Armstrong CM, Imlay LS, Hodge DM, Pidathala C, Roberts NJ, Park J, Mikati M, Sharma R, Lawrenson AS, Tolia NH, Berry NG, O'Neill PM, John AR
An elastic element in the protocadherin-15 tip link of the inner ear.
1. Nat Commun - published November 1, 2016
2. Araya-Secchi R, Neel BL, Sotomayor M
From Mfd to TRCF and Back Again - A Perspective on Bacterial Transcription-Coupled Nucleotide Excision Repair.
1. Photochem Photobiol - published November 1, 2016
2. Deaconescu AM, Suhanovsky MM
Structural and molecular analysis of a protective epitope of Lyme disease antigen OspA and antibody interactions.
1. J Mol Recognit - published November 1, 2016
2. Shandilya S, Kurt Yilmaz N, Sadowski A, Monir E, Schiller ZA, Thomas WD Jr, Klempner MS, Schiffer CA, Wang Y
Patient-derived glioblastoma stem cells respond differentially to targeted therapies.
1. Oncotarget - published November 1, 2016
2. Kanabur P, Guo S, Simonds GR, Kelly DF, Gourdie RG, Verbridge SS, Sheng Z
Extension of research data repository system to support direct compute access to biomedical datasets: enhancing Dataverse to support large datasets.
1. Ann N Y Acad Sci - published November 1, 2016
2. McKinney B, Meyer PA, Crosas M, Sliz P
Perspective: revisiting the field dependence of TROSY sensitivity.
1. J Biomol NMR - published November 1, 2016
2. Takeuchi K, Arthanari H, Wagner G
Molecular Structures of Transcribing RNA Polymerase I.
1. Mol Cell - published November 1, 2016
2. Tafur L, Sadian Y, Hoffmann NA, Jakobi AJ, Wetzel R, Hagen WJ, Sachse C, Müller CW
Many Activities, One Structure: Functional Plasticity of Ribozyme Folds.
1. Molecules - published November 1, 2016
2. Lau MW, Ferré-D'Amaré AR
Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN.
1. Mol Cell - published November 1, 2016
2. Stingele J, Bellelli R, Alte F, Hewitt G, Sarek G, Maslen SL, Tsutakawa SE, Borg A, Kjær S, Tainer JA, Skehel JM, Groll M, Boulton SJ
Extending Halogen-Based Medicinal Chemistry to Proteins: Iodo-Insulin as a Case Study.
1. J Biol Chem - published November 1, 2016
2. El Hage K, Pandyarajan V, Phillips NB, Smith BJ, Menting JG, Whittaker J, Lawrence MC, Meuwly M, Weiss MA
Structural Basis for the Subversion of MAP Kinase Signaling by an Intrinsically Disordered Parasite Secreted Agonist.
1. Structure - published November 1, 2016
2. Pellegrini E, Palencia A, Braun L, Kapp U, Bougdour A, Belrhali H, Bowler MW, Hakimi MA
The Cytoplasmic Tail Domain of Epstein-Barr Virus gH Regulates Membrane Fusion Activity through Altering gH Binding to gp42 and Epithelial Cell Attachment.
1. MBio - published November 1, 2016
2. Chen J, Jardetzky TS, Longnecker R
Characterization of transfer function, resolution and depth of field of a soft X-ray microscope applied to tomography enhancement by Wiener deconvolution.
1. Biomed Opt Express - published November 1, 2016
2. Otón J, Pereiro E, Pérez-Berná AJ, Millach L, Sorzano CO, Marabini R, Carazo JM
The reactivity and conformational control of cyclic tetrapeptides derived from aziridine-containing amino acids.
1. Chem Sci - published November 1, 2016
2. Chung BKW, White CJ, Scully CCG, Yudin AK