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  • The SBGrid Consortium provides structural biologists worldwide with access to the software they need to discover the shapes of the molecules of life. Read more in eLIFE and Acta Cryst.

  • SBCloud: AWS platform optimized for structural biology; pre-configured with scientific software for cryoEM & other techniques; user-friendly Open OnDemand interface; seamless Slurm job submission.

  • Capsules isolate the software runtime environment, encapsulating executables, libraries, and version-specific dependencies to provide conflict-free, zero-configuration access to structural biology software. Learn more.

  • The Project MAC display system, circa 1965. Read more about the history of molecular graphics software and UCSF Chimera in our SBGrid Tale featuring Bob Langridge and Tom Ferrin.

  • Train the Trainer Workshops: continuing education for structural biology mentors on cryoEM data processing workflows; resources PIs can take back to the laboratory. Funded by NIH R25 GM151273.

  • Personal Installation Manager: a structural biology app store; users install preferred applications/ versions on laptops or personal workstations, with graphical or CLI interfaces for Mac or Linux. More details.

SBGrid Consortium homepage

Recent Software Updates

Software updates
May 02 | Scipion

an image processing framework to obtain 3D models of macromolecular complexes using 3D EM that allows you to execute workflows combining di… >>

May 02 | Xmipp

(X-Window-based Microscopy Image Processing Package) a suite of image processing programs primarily aimed at single-particle 3D electron mi… >>

May 01 | MemBrain

a pipeline for the automated detection of membrane-bound proteins in cryo-electron tomograms. It utilizes the geometry of a pre-segmented m… >>

Apr 30 | CryoFold

is graphical user interface for the CryoFold method, which integrates several computational techniques (MAINMAST, Targeted Molecular Dynami… >>

Apr 29 | cryovia

An image analysis toolkit for the quantification of membrane structures from cryo-EM micrographs >>

Apr 29 | RosettaDDGPrediction

is a Python package to run Rosetta-based protocols for the prediction of the ΔΔG of stability upon mutation of a monomeric protein or the Δ… >>

Apr 24 | cryo-MEM

a software for membrane signal subtraction to facilitate high-resolution cryo-EM reconstruction of membrane proteins embedded in their nati… >>

Apr 24 | miffi

a tool for Cryo-EM micrograph filtering utilizing Fourier space information >>

Apr 22 | tomoCPT

is a deep learning based program for enabling centroid prediction of objects in 3D cryo-tomograms. >>

Apr 16 | AreTomo3

a multi-GPU accelerated software package that enables real-time fully automated reconstruction of cryoET tomograms in parallel with cryoET … >>

Thanks to the National Science Foundation

With partial support from the NIH R25 Continuing Education for Structural Biology Mentors #GM151273, in collaboration with Co-PI Jamaine Davis; the NSF Research Coordination Network MCB #0639193, and NSF EAGER #1448069. Please cite SBGrid's eLife paper and follow our publication guidelines.

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Latest upgrades from SBGrid, including latest software updates, new members and special events. Published montly by SBGrid.

SBGrid Webinar Series

Join us for our Software Webinar Series - Tuesdays at 12pm ET - to hear from software developers about what's new in structural biology. Community members connect via Zoom. Subscribe …

SBGrid/Harvard Shield

Capsules Technology

We have recently published a manuscript describing our Capsules technology used to deploy SBGrid and BioGrids software collections. Read more in Acta Cryst Section D, special 75th ICUR anniversary issue, …

Mind and Muscle

Mind and Muscle

From ancient Greece to modern day, people have often considered activities of the mind and muscle as fundamentally separate, even opposite, pursuits. Consider the contrasting stereotypes of a nerdy brainiac …

The Shapes of Energy

The Shapes of Energy

In Woods Hole, Mass., the Atlantic breeze mixes with the hum of microscopes and the chatter of biologists. There, in a summer neurobiology course, Luke Chao first became enthralled by …

Member publications

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