Our position postings page advertises open positions for postdocs, students, faculty, and staff in SBGrid member laboratories and institutions. Please send brief descriptions to Michelle. Postings will remain online for 60 days
Deaconescu Laboratory
Brown University
POSTDOCTORAL POSITIONS
The Deaconescu Lab at Brown University has two openings for postdoc candidates. The laboratory's interests lie primarily in stress responses, with particular emphasis on responses to DNA damage and the mechanochemistry of DNA-based motors. We utilize a combination of biochemical, biophysical and structural techniques. (e.g. X-ray crystallography, small-angle X-ray scattering, transmission electron microscopy). For examples of work, please see Vemu et al. Science (in press), Le TT et al. Cell (2018), Deaconescu et al. Photochemistry and Photobiology (2017), Kutter et al. JMB (2016), Szyk et al, Cell (2014), Deaconescu et al., PNAS (2012), Szyk et al., NSMB (2012) and Deaconescu et al., TIBS (2013).
A successful candidate should have an established track-record of publications in peer-reviewed journals; solid experience with protein biochemistry (including their purification from E.coli/yeast expression, functional characterization and assay development). Prior knowledge of crystallography and/or single-particle electron microscopy is highly desirable. Crystals/data at various stages of the structure determination process are available for immediate work. Must be highly motivated and work independently as well as in a team. Excellent spoken and written English are required. New Ph.D. graduates are encouraged to apply.
Interested candidates should send a CV, one page research experience summary and contact information for three references to alexandra_deaconescu@brown.edu. Salary and starting date are negotiable. Please write Postdoctoral Candidate in the e-mail subject header. Brown University, an Ivy League school, is located less than one hour away by train from Boston. Lab webpage: https://deaconesculab.com
Posting Date: September 6, 2018
Roll-Mecak Laboratory
National Institutes of Health - NINDS & NHLBI
We are currently seeking an outstanding individual to join our team as a Senior Scientist in Cryo-Electron Microscopy at the National Institute of Neurological Disorders and Stroke in Bethesda. The successful candidate will join a multidisciplinary group with expertise in molecular biology, protein biochemistry, X-Ray crystallography and high-resolution fluorescence microscopy with a mission to provide molecular insights into important cytoskeletal regulators. The lab has regular access to a state-of-the art cryo-EM facility which includes a Titan Krios with a K2 direct electron detector with energy filter and will soon add a 200 kV Talos Arctica.
The Senior Scientist will:
Bring innovative structural biology technologies, with a focus on cryo-EM as a method for novel protein structure determination Design and conduct experiments for all aspects of structure determination by Cryo-EM, including grid preparation, data collection and processing and 3-D model building. Work closely with molecular biologists, protein scientists, biophysicists as part of an integrated structural biology effort Interface with the central trans-NIH cryo-EM facility for optimal data collection strategies Training, assisting and overseeing scientists in the group in sample preparation for cryo-EM, data collection and image processing Contribute to the strategic planning of our group in cryo-EM
Qualifications
A minimum of a Ph.D. or equivalent is required Postdoctoral experience in structural biology or related field is required A minimum of 3 years of research experience in single particle cryo-electron microscopy in industry or an academic institution is required Deep scientific expertise in structural biology and high-resolution structure determination is required Strong record of external publications and presentations is required Experience in scientific programming and ability to work with the latest relevant software packages Experience in cryo-electron tomography a plus Skills in working and communicating with scientists at all levels
Salary and benefits are generous and commensurate with research experience and accomplishments. The DC area is a great place to live with access to many cultural and outdoors activities. NINDS offers a rich and diverse scientific environment and the resources on campus are unparalleled. More information can be found at: https://neuroscience.nih.gov/ninds/rm_lab/ and https://neuroscience.nih.gov/ninds/Home.aspx
To apply: Please send a cover letter, curriculum vitae, bibliography, a one-page statement of research experience relevant to this position and the names of three references to Antonina@mail.nih.gov Applications will be considered until December 1, 2018.
Posting Date: August 24, 2018