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89 Member Publications for August

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Monitoring functional RNA binding of RNA-dependent ATPase enzymes such as SF2 helicases using RNA dependent ATPase assays: A RIG-I case study.
1. Methods Enzymol - published August 14, 2022
2. Guo R, Pyle AM
Molecular dynamics analysis of the structural properties of the transglutaminases of Kutzneria albida and Streptomyces mobaraensis.
1. Comput Struct Biotechnol J - published August 11, 2022
2. Giordano D, Langini C, Caflisch A, Marabotti A, Facchiano A
A pathogenic proteolysis-resistant huntingtin isoform induced by an antisense oligonucleotide maintains huntingtin function.
1. JCI Insight - published August 9, 2022
2. Kim H, Lenoir S, Helfricht A, Jung T, Karneva ZK, Lee Y, Beumer W, van der Horst GB, Anthonijsz H, Buil LC, van der Ham F, Platenburg GJ, Purhonen P, Hebert H, Humbert S, Saudou F, Klein P, Song JJ
Modular Adapters Utilizing Binders of Different Molecular Types Expand Cell-Targeting Options for Adenovirus Gene Delivery.
1. Bioconjug Chem - published August 9, 2022
2. Freitag PC, Brandl F, Brücher D, Weiss F, Dreier B, Plückthun A
The mechanism of RNA capping by SARS-CoV-2.
1. Nature - published August 9, 2022
2. Park GJ, Osinski A, Hernandez G, Eitson JL, Majumdar A, Tonelli M, Henzler-Wildman K, Pawłowski K, Chen Z, Li Y, Schoggins JW, Tagliabracci VS
SARS-CoV-2 hybrid immunity: silver bullet or silver lining?
1. Nat Rev Immunol - published August 9, 2022
2. Suryawanshi R, Ott M
Novel interaction interfaces mediate the interaction between the NEIL1 DNA glycosylase and mitochondrial transcription factor A.
1. Front Cell Dev Biol - published August 8, 2022
2. Sharma N, Thompson MK, Arrington JF, Terry DM, Chakravarthy S, Prevelige PE, Prakash A
Autoantibody mimicry of hormone action at the thyrotropin receptor.
1. Nature - published August 8, 2022
2. Faust B, Billesbølle CB, Suomivuori CM, Singh I, Zhang K, Hoppe N, Pinto AFM, Diedrich JK, Muftuoglu Y, Szkudlinski MW, Saghatelian A, Dror RO, Cheng Y, Manglik A
Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
1. Elife - published August 8, 2022
2. Schrecker M, Castaneda JC, Devbhandari S, Kumar C, Remus D, Hite RK
Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.
1. J Biol Chem - published August 8, 2022
2. Orlando BJ, Dominik PK, Roy S, Ogbu CP, Erramilli SK, Kossiakoff AA, Vecchio AJ
Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape.
1. Lancet Infect Dis - published August 8, 2022
2. Mazur NI, Terstappen J, Baral R, Bardají A, Beutels P, Buchholz UJ, Cohen C, Crowe JE Jr, Cutland CL, Eckert L, Feikin D, Fitzpatrick T, Fong Y, Graham BS, Heikkinen T, Higgins D, Hirve S, Klugman KP, Kragten-Tabatabaie L, Lemey P, Libster R, Löwensteyn Y, Mejias A, Munoz FM, Munywoki PK, Mwananyanda L, Nair H, Nunes MC, Ramilo O, Richmond P, Ruckwardt TJ, Sande C, Srikantiah P, Thacker N, Waldstein KA, Weinberger D, Wildenbeest J, Wiseman D, Zar HJ, Zambon M, Bont L
Programmable DARPin-based receptors for the detection of thrombotic markers.
1. Nat Chem Biol - published August 8, 2022
2. Strittmatter T, Wang Y, Bertschi A, Scheller L, Freitag PC, Ray PG, Stuecheli P, Schaefer JV, Reinberg T, Tsakiris D, Plückthun A, Ye H, Fussenegger M
mRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variant.
1. Commun Biol - published August 6, 2022
2. Nanishi E, McGrath ME, O'Meara TR, Barman S, Yu J, Wan H, Dillen CA, Menon M, Seo HS, Song K, Xu AZ, Sebastian L, Brook B, Bosco AN, Borriello F, Ernst RK, Barouch DH, Dhe-Paganon S, Levy O, Frieman MB, Dowling DJ
Structure-based evolutionary relationship between IscB and Cas9.
1. Cell Res - published August 5, 2022
2. Jia N, Patel DJ
The TPR domain of PgaA is a multifunctional scaffold that binds PNAG and modulates PgaB-dependent polymer processing.
1. PLoS Pathog - published August 5, 2022
2. Pfoh R, Subramanian AS, Huang J, Little DJ, Forman A, DiFrancesco BR, Balouchestani-Asli N, Kitova EN, Klassen JS, Pomès R, Nitz M, Howell PL
Reply to Comment on "Binding Affinity Determines Substrate Specificity and Enables Discovery of substrates for N-Myristoyltransferases".
1. ACS Catal - published August 5, 2022
2. Su D, Kosciuk T, Lin H
Modulation of pre-mRNA structure by hnRNP proteins regulates alternative splicing of MALT1.
1. Sci Adv - published August 5, 2022
2. Jones AN, Graß C, Meininger I, Geerlof A, Klostermann M, Zarnack K, Krappmann D, Sattler M
Immediate and Sustained Effects of Cobalt and Zinc-Containing Pigments on Macrophages.
1. Front Immunol - published August 5, 2022
2. Devcic J, Dussol M, Collin-Faure V, Pérard J, Fenel D, Schoehn G, Carrière M, Rabilloud T, Dalzon B
BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL.
1. Cancer Discov - published August 5, 2022
2. Xia M, David L, Teater M, Gutierrez J, Wang X, Meydan C, Lytle A, Slack GW, Scott DW, Morin RD, Onder O, Elenitoba-Johnson KSJ, Zamponi N, Cerchietti L, Lu T, Philippar U, Fontan L, Wu H, Melnick AM
The SOS response-associated peptidase (SRAP) domain of YedK catalyzes ring opening of abasic sites and reversal of its DNA-protein crosslink.
1. J Biol Chem - published August 4, 2022
2. Paulin KA, Cortez D, Eichman BF
Coupling to short linear motifs creates versatile PME-1 activities in PP2A holoenzyme demethylation and inhibition.
1. Elife - published August 4, 2022
2. Li Y, Balakrishnan VK, Rowse M, Wu CG, Bravos AP, Yadav VK, Ivarsson Y, Strack S, Novikova IV, Xing Y
Inhibition of H1 and H5 Influenza A Virus Entry by Diverse Macrocyclic Peptides Targeting the Hemagglutinin Stem Region.
1. ACS Chem Biol - published August 4, 2022
2. Pascha MN, Thijssen V, Egido JE, Linthorst MW, van Lanen JH, van Dongen DAA, Hopstaken AJP, van Kuppeveld FJM, Snijder J, de Haan CAM, Jongkees SAK
Rotavirus VP4 Epitope of a Broadly Neutralizing Human Antibody Defined by Its Structure Bound with an Attenuated-Strain Virion.
1. J Virol - published August 4, 2022
2. Jenni S, Li Z, Wang Y, Bessey T, Salgado EN, Schmidt AG, Greenberg HB, Jiang B, Harrison SC
Short Arrestin-3-Derived Peptides Activate JNK3 in Cells.
1. Int J Mol Sci - published August 4, 2022
2. Perry-Hauser NA, Kaoud TS, Stoy H, Zhan X, Chen Q, Dalby KN, Iverson TM, Gurevich VV, Gurevich EV
PEX5 translocation into and out of peroxisomes drives matrix protein import.
1. Mol Cell - published August 4, 2022
2. Skowyra ML, Rapoport TA
A Review of Clinical Efficacy Data Supporting Emergency Use Authorization for COVID-19 Therapeutics and Lessons for Future Pandemics.
1. Clin Transl Sci - published August 4, 2022
2. Yoo SH, Kim L, Lu M, Nagoshi K, Namchuk MN
A conserved sequence motif in the E. coli soluble FAD-containing pyridine nucleotide transhydrogenase is important for reaction efficiency.
1. J Biol Chem - published August 3, 2022
2. Partipilo M, Yang G, Mascotti ML, Wijma HJ, Slotboom DJ, Fraaije MW
Teixobactin kills bacteria by a two-pronged attack on the cell envelope.
1. Nature - published August 3, 2022
2. Shukla R, Lavore F, Maity S, Derks MGN, Jones CR, Vermeulen BJA, Melcrová A, Morris MA, Becker LM, Wang X, Kumar R, Medeiros-Silva J, van Beekveld RAM, Bonvin AMJJ, Lorent JH, Lelli M, Nowick JS, MacGillavry HD, Peoples AJ, Spoering AL, Ling LL, Hughes DE, Roos WH, Breukink E, Lewis K, Weingarth M
The transcription factor FoxP3 can fold into two dimerization states with divergent implications for regulatory T cell function and immune homeostasis.
1. Immunity - published August 3, 2022
2. Leng F, Zhang W, Ramirez RN, Leon J, Zhong Y, Hou L, Yuki K, van der Veeken J, Rudensky AY, Benoist C, Hur S
¹⁵N-Detected TROSY NMR experiments to study large disordered proteins in high-field magnets.
1. Chem Commun (Camb) - published August 3, 2022
2. Dubey A, Viennet T, Chhabra S, Takeuchi K, Seo HC, Bermel W, Frueh DP, Arthanari H
Characterization of N-terminal RYR2 variants outside CPVT1 hotspot regions using patient iPSCs reveal pathogenesis and therapeutic potential.
1. Stem Cell Reports - published August 3, 2022
2. Stutzman MJ, Kim CSJ, Tester DJ, Hamrick SK, Dotzler SM, Giudicessi JR, Miotto MC, Gc JB, Frank J, Marks AR, Ackerman MJ
A mitotic chromatin phase transition prevents perforation by microtubules.
1. Nature - published August 3, 2022
2. Schneider MWG, Gibson BA, Otsuka S, Spicer MFD, Petrovic M, Blaukopf C, Langer CCH, Batty P, Nagaraju T, Doolittle LK, Rosen MK, Gerlich DW
Blockade of the Adenylate Cyclase Toxin Synergizes with Opsonizing Antibodies to Protect Mice against Bordetella pertussis.
1. mBio - published August 3, 2022
2. DiVenere AM, Amengor D, Silva RP, Goldsmith JA, McLellan JS, Maynard JA
Role of a "Magic" Methyl: 2'-Deoxy-2'-α-F-2'-β-C-methyl Pyrimidine Nucleotides Modulate RNA Interference Activity through Synergy with 5'-Phosphate Mimics and Mitigation of Off-Target Effects.
1. J Am Chem Soc - published August 3, 2022
2. Guenther DC, Mori S, Matsuda S, Gilbert JA, Willoughby JLS, Hyde S, Bisbe A, Jiang Y, Agarwal S, Madaoui M, Janas MM, Charisse K, Maier MA, Egli M, Manoharan M
Potently neutralizing and protective anti-human metapneumovirus antibodies target diverse sites on the fusion glycoprotein.
1. Immunity - published August 3, 2022
2. Rappazzo CG, Hsieh CL, Rush SA, Esterman ES, Delgado T, Geoghegan JC, Wec AZ, Sakharkar M, Más V, McLellan JS, Walker LM
Dynamics of integrin α5β1, fibronectin, and their complex reveal sites of interaction and conformational change.
1. J Biol Chem - published August 2, 2022
2. Su Y, Iacob RE, Li J, Engen JR, Springer TA
Integrated AlphaFold2 and DEER investigation of the conformational dynamics of a pH-dependent APC antiporter.
1. Proc Natl Acad Sci U S A - published August 2, 2022
2. Del Alamo D, DeSousa L, Nair RM, Rahman S, Meiler J, Mchaourab HS
Two interaction surfaces between XPA and RPA organize the preincision complex in nucleotide excision repair.
1. Proc Natl Acad Sci U S A - published August 2, 2022
2. Kim M, Kim HS, D'Souza A, Gallagher K, Jeong E, Topolska-Wós A, Ogorodnik Le Meur K, Tsai CL, Tsai MS, Kee M, Tainer JA, Yeo JE, Chazin WJ, Schärer OD
Antibody binding increases the flexibility of the prion protein.
1. Biochim Biophys Acta Proteins Proteom - published August 2, 2022
2. Ilie IM, Caflisch A
Shelterin is a dimeric complex with extensive structural heterogeneity.
1. Proc Natl Acad Sci U S A - published August 2, 2022
2. Zinder JC, Olinares PDB, Svetlov V, Bush MW, Nudler E, Chait BT, Walz T, de Lange T
Structural basis of mRNA maturation: Time to put it together.
1. Curr Opin Struct Biol - published August 2, 2022
2. Vorländer MK, Pacheco-Fiallos B, Plaschka C
Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles.
1. Proc Natl Acad Sci U S A - published August 2, 2022
2. Syed AM, Ciling A, Taha TY, Chen IP, Khalid MM, Sreekumar B, Chen PY, Kumar GR, Suryawanshi R, Silva I, Milbes B, Kojima N, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Spraggon L, Tabata T, Ott M, Doudna JA
Golgi stress induces SIRT2 to counteract Shigella infection via defatty-acylation.
1. Nat Commun - published August 2, 2022
2. Wang M, Zhang Y, Komaniecki GP, Lu X, Cao J, Zhang M, Yu T, Hou D, Spiegelman NA, Yang M, Price IR, Lin H
On the formation of ordered protein assemblies in cell-cell interfaces.
1. Proc Natl Acad Sci U S A - published August 2, 2022
2. Boni N, Shapiro L, Honig B, Wu Y, Rubinstein R
Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans.
1. Life Sci Alliance - published August 1, 2022
2. Stogios PJ, Liston SD, Semper C, Quade B, Michalska K, Evdokimova E, Ram S, Otwinowski Z, Borek D, Cowen LE, Savchenko A
Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma.
1. Nat Commun - published August 1, 2022
2. Coy S, Wang S, Stopka SA, Lin JR, Yapp C, Ritch CC, Salhi L, Baker GJ, Rashid R, Baquer G, Regan M, Khadka P, Cole KA, Hwang J, Wen PY, Bandopadhayay P, Santi M, De Raedt T, Ligon KL, Agar NYR, Sorger PK, Touat M, Santagata S
Highly protective antimalarial antibodies via precision library generation and yeast display screening.
1. J Exp Med - published August 1, 2022
2. Banach BB, Tripathi P, Da Silva Pereira L, Gorman J, Nguyen TD, Dillon M, Fahad AS, Kiyuka PK, Madan B, Wolfe JR, Bonilla B, Flynn B, Francica JR, Hurlburt NK, Kisalu NK, Liu T, Ou L, Rawi R, Schön A, Shen CH, Teng IT, Zhang B, Pancera M, Idris AH, Seder RA, Kwong PD, DeKosky BJ
Monoclonal antibodies binding data for SARS-CoV-2 proteins.
1. Data Brief - published August 1, 2022
2. Mishra N, Teyra J, Boytz R, Miersch S, Merritt TN, Cardarelli L, Gorelik M, Mihalic F, Jemth P, Davey RA, Sidhu SS, Leung DW, Amarasinghe GK
Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
1. Proc Natl Acad Sci U S A - published August 1, 2022
2. Zhao J, Makhija S, Zhou C, Zhang H, Wang Y, Muralidharan M, Huang B, Cheng Y
Emerging roles of spliceosome in cancer and immunity.
1. Protein Cell - published August 1, 2022
2. Yang H, Beutler B, Zhang D
Discovery of a drug to treat airway mucus hypersecretion.
1. Clin Transl Med - published August 1, 2022
2. Dickey BF, Lai Y, Frick M, Brunger AT
A lipopolysaccharide-dependent phage infects a pseudomonad phytopathogen and can evolve to evade phage resistance.
1. Environ Microbiol - published August 1, 2022
2. Warring SL, Malone LM, Jayaraman J, Easingwood RA, Rigano LA, Frampton RA, Visnovsky SB, Addison SM, Hernandez L, Pitman AR, Lopez Acedo E, Kleffmann T, Templeton MD, Bostina M, Fineran PC
The Innate Immune Protein Calprotectin Interacts With and Encases Biofilm Communities of Pseudomonas aeruginosa and Staphylococcus aureus.
1. Front Cell Infect Microbiol - published August 1, 2022
2. Baishya J, Everett JA, Chazin WJ, Rumbaugh KP, Wakeman CA
The crystal structure of CbpD clarifies substrate-specificity motifs in chitin-active lytic polysaccharide monooxygenases.
1. Acta Crystallogr D Struct Biol - published August 1, 2022
2. Dade CM, Douzi B, Cambillau C, Ball G, Voulhoux R, Forest KT
Room-temperature serial synchrotron crystallography of Drosophila cryptochrome.
1. Acta Crystallogr D Struct Biol - published August 1, 2022
2. Schneps CM, Ganguly A, Crane BR
Crystal structures of glutamyl-tRNA synthetase from Elizabethkingia anopheles and E. meningosepticum.
1. Acta Crystallogr F Struct Biol Commun - published August 1, 2022
2. Brooks L, Subramanian S, Dranow DM, Mayclin SJ, Myler PJ, Asojo OA
Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt.
1. J Biol Chem - published August 1, 2022
2. Yu Z, Chen J, Takagi E, Wang F, Saha B, Liu X, Joubert LM, Gleason CE, Jin M, Li C, Nowotny C, Agard D, Cheng Y, Pearce D
A Homozygous Missense Variant in KRT25 Underlying Overlapping Phenotype with Woolly Hair and Dental Anomalies.
1. J Invest Dermatol - published August 1, 2022
2. Raza R, Chhabra G, Bilal M, Ndiaye MA, Liaqat K, Nawaz S, Sgro JY, Rayment I, Ahmad W, Ahmad N
Engineered IL13 variants direct specificity of IL13Rα2-targeted CAR T cell therapy.
1. Proc Natl Acad Sci U S A - published August 1, 2022
2. Stern LA, Gholamin S, Moraga I, Yang X, Saravanakumar S, Cohen JR, Starr R, Aguilar B, Salvary V, Hibbard JC, Kalbasi A, Shepphird JK, O'Hearn J, Garcia KC, Brown CE
Oropouche orthobunyavirus infection is mediated by the cellular host factor Lrp1.
1. Proc Natl Acad Sci U S A - published August 1, 2022
2. Schwarz MM, Price DA, Ganaie SS, Feng A, Mishra N, Hoehl RM, Fatma F, Stubbs SH, Whelan SPJ, Cui X, Egawa T, Leung DW, Amarasinghe GK, Hartman AL
System-wide analyses reveal essential roles of N-terminal protein modification in bacterial membrane integrity.
1. iScience - published August 1, 2022
2. Yang CI, Zhu Z, Jones JJ, Lomenick B, Chou TF, Shan SO
Durability of Heterologous and Homologous COVID-19 Vaccine Boosts.
1. JAMA Netw Open - published August 1, 2022
2. Tan CS, Collier AY, Yu J, Liu J, Chandrashekar A, McMahan K, Jacob-Dolan C, He X, Roy V, Hauser BM, Munt JE, Mallory ML, Mattocks M, Powers JM, Meganck RM, Rowe M, Hemond R, Bondzie EA, Jaegle KH, Baric RS, Schmidt AG, Alter G, Le Gars M, Sadoff J, Barouch DH
B-to-A transition in target DNA during retroviral integration.
1. Nucleic Acids Res - published August 1, 2022
2. Jóźwik IK, Li W, Zhang DW, Wong D, Grawenhoff J, Ballandras-Colas A, Aiyer S, Cherepanov P, Engelman AN, Lyumkis D
Molecular explorations of cancer biology and therapeutics at PDB-101.
1. Oncogene - published August 1, 2022
2. Goodsell DS, Dutta S, Voigt M, Zardecki C, Burley SK
Proximity Labeling Reveals Spatial Regulation of the Anaphase-Promoting Complex/Cyclosome by a Microtubule Adaptor.
1. ACS Chem Biol - published August 1, 2022
2. Cao X, Shami Shah A, Sanford EJ, Smolka MB, Baskin JM
Molecular architecture of bacterial type IV secretion systems.
1. PLoS Pathog - published August 1, 2022
2. Sheedlo MJ, Ohi MD, Lacy DB, Cover TL
Prokaryotic innate immunity through pattern recognition of conserved viral proteins.
1. Science - published August 1, 2022
2. Gao LA, Wilkinson ME, Strecker J, Makarova KS, Macrae RK, Koonin EV, Zhang F
An Antibody from Single Human V_H-rearranging Mouse Neutralizes All SARS-CoV-2 Variants Through BA.5 by Inhibiting Membrane Fusion.
1. Sci Immunol - published August 1, 2022
2. Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease M^pro and Papain-like Protease PL^pro of SARS-CoV-2.
1. J Chem Inf Model - published August 1, 2022
2. Santos LH, Kronenberger T, Almeida RG, Silva EB, Rocha REO, Oliveira JC, Barreto LV, Skinner D, Fajtová P, Giardini MA, Woodworth B, Bardine C, Lourenço AL, Craik CS, Poso A, Podust LM, McKerrow JH, Siqueira-Neto JL, O'Donoghue AJ, da Silva Júnior EN, Ferreira RS
A haem-sequestering plant peptide promotes iron uptake in symbiotic bacteria.
1. Nat Microbiol - published August 1, 2022
2. Sankari S, Babu VMP, Bian K, Alhhazmi A, Andorfer MC, Avalos DM, Smith TA, Yoon K, Drennan CL, Yaffe MB, Lourido S, Walker GC
A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
1. Sci Adv - published August 1, 2022
2. Barnes CO, Schoofs T, Gnanapragasam PNP, Golijanin J, Huey-Tubman KE, Gruell H, Schommers P, Suh-Toma N, Lee YE, Cetrulo Lorenzi JC, Piechocka-Trocha A, Scheid JF, West AP Jr, Walker BD, Seaman MS, Klein F, Nussenzweig MC, Bjorkman PJ
Reproductive Ophthalmology: The Intersection of Inherited Eye Diseases and Reproductive Technologies.
1. Retina - published August 1, 2022
2. Park JG, Xu CL, Boyd A, Aghajanova L, Mahajan VB, Wood EH
Elucidation of an mTORC2-PKC-NRF2 pathway that sustains the ATF4 stress response and identification of Sirt5 as a key ATF4 effector.
1. Cell Death Discov - published August 1, 2022
2. Li R, Wilson KF, Cerione RA
PH domain-mediated autoinhibition and oncogenic activation of Akt.
1. Elife - published August 1, 2022
2. Bae H, Viennet T, Park E, Chu N, Salguero A, Eck MJ, Arthanari H, Cole PA
Microfluidic-Derived Detection of Protein-Facilitated Copper Flux Across Lipid Membranes.
1. Anal Chem - published August 1, 2022
2. Górecki K, Hansen JS, Li P, Nayeri N, Lindkvist-Petersson K, Gourdon P
Bps polysaccharide of Bordetella pertussis resists antimicrobial peptides by functioning as a dual surface shield and decoy and converts Escherichia coli into a respiratory pathogen.
1. PLoS Pathog - published August 1, 2022
2. Fullen AR, Gutierrez-Ferman JL, Yount KS, Love CF, Choi HG, Vargas MA, Raju D, Corps KN, Howell PL, Dubey P, Deora R
Disulfide-crosslink analysis of the ubiquitin ligase Hrd1 complex during endoplasmic reticulum-associated protein degradation.
1. J Biol Chem - published August 1, 2022
2. Pisa R, Rapoport TA
Stitching and registering highly multiplexed whole slide images of tissues and tumors using ASHLAR.
1. Bioinformatics - published August 1, 2022
2. Muhlich JL, Chen YA, Yapp C, Russell D, Santagata S, Sorger PK
Conformation and Pairing Properties of an O⁶-Methyl-2'-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA.
1. Chem Res Toxicol - published August 1, 2022
2. Kellum AH Jr, Pallan PS, Nilforoushan A, Sturla SJ, Stone MP, Egli M
Visualizing molecular interactions that determine assembly of a bullet-shaped vesicular stomatitis virus particle.
1. Nat Commun - published August 1, 2022
2. Jenni S, Horwitz JA, Bloyet LM, Whelan SPJ, Harrison SC
SH3 domain regulation of RhoGAP activity: Crosstalk between p120RasGAP and DLC1 RhoGAP.
1. Nat Commun - published August 1, 2022
2. Chau JE, Vish KJ, Boggon TJ, Stiegler AL
Integrative model of the FSH receptor reveals the structural role of the flexible hinge region.
1. Structure - published August 1, 2022
2. Nagel M, Moretti R, Paschke R, von Bergen M, Meiler J, Kalkhof S
Author Correction: A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes.
1. Nat Commun - published August 1, 2022
2. Coelho CH, Tang WK, Burkhardt M, Galson JD, Muratova O, Salinas ND, Alves E Silva TL, Reiter K, MacDonald NJ, Nguyen V, Herrera R, Shimp R, Narum DL, Byrne-Steele M, Pan W, Hou X, Brown B, Eisenhower M, Han J, Jenkins BJ, Doritchamou JYA, Smelkinson MG, Vega-Rodríguez J, Trück J, Taylor JJ, Sagara I, Healy SA, Renn JP, Tolia NH, Duffy PE
Herpes Simplex Virus 1 Entry Glycoproteins Form Complexes before and during Membrane Fusion.
1. mBio - published August 1, 2022
2. Pataki Z, Rebolledo Viveros A, Heldwein EE
A structure-based mechanism for displacement of the HEXIM adapter from 7SK small nuclear RNA.
1. Commun Biol - published August 1, 2022
2. Pham VV, Gao M, Meagher JL, Smith JL, D'Souza VM
Hydroxamic Acid-Modified Peptide Library Provides Insights into the Molecular Basis for the Substrate Selectivity of HDAC Corepressor Complexes.
1. ACS Chem Biol - published August 1, 2022
2. Archibald LJ, Brown EA, Millard CJ, Watson PJ, Robertson NS, Wang S, Schwabe JWR, Jamieson AG
A Chemical Approach to Introduce 2,6-Diaminopurine and 2-Aminoadenine Conjugates into Oligonucleotides without Need for Protecting Groups.
1. Org Lett - published August 1, 2022
2. Madaoui M, Datta D, Wassarman K, Zlatev I, Egli M, Ross BS, Manoharan M
Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin.
1. Cell Rep - published August 1, 2022
2. Goldsmith JA, DiVenere AM, Maynard JA, McLellan JS
Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses.
1. Immunity - published August 1, 2022
2. McLeod B, Mabrouk MT, Miura K, Ravichandran R, Kephart S, Hailemariam S, Pham TP, Semesi A, Kucharska I, Kundu P, Huang WC, Johnson M, Blackstone A, Pettie D, Murphy M, Kraft JC, Leaf EM, Jiao Y, van de Vegte-Bolmer M, van Gemert GJ, Ramjith J, King CR, MacGill RS, Wu Y, Lee KK, Jore MM, King NP, Lovell JF, Julien JP