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103 Member Publications for April 2017

Structural and functional studies of ferredoxin and oxygenase components of 3-nitrotoluene dioxygenase from Diaphorobacter sp. strain DS2.
1. PLoS One - published April 28, 2017
2. Kumari A, Singh D, Ramaswamy S, Ramanathan G
NMRbox: A Resource for Biomolecular NMR Computation.
1. Biophys J - published April 25, 2017
2. Maciejewski MW, Schuyler AD, Gryk MR, Moraru II, Romero PR, Ulrich EL, Eghbalnia HR, Livny M, Delaglio F, Hoch JC
L1000CDS²: LINCS L1000 characteristic direction signatures search engine.
1. NPJ Syst Biol Appl - published April 18, 2017
2. Duan Q, Reid SP, Clark NR, Wang Z, Fernandez NF, Rouillard AD, Readhead B, Tritsch SR, Hodos R, Hafner M, Niepel M, Sorger PK, Dudley JT, Bavari S, Panchal RG, Ma'ayan A
Approaches for Conjugating Tailor-Made Polymers to Proteins.
1. Methods Enzymol - published April 17, 2017
2. Paeth M, Stapleton J, Dougherty ML, Fischesser H, Shepherd J, McCauley M, Falatach R, Page RC, Berberich JA, Konkolewicz D
Strategies for Biophysical Characterization of Protein-Polymer Conjugates.
1. Methods Enzymol - published April 17, 2017
2. Williams C, Dougherty ML, Makaroff K, Stapleton J, Konkolewicz D, Berberich JA, Page RC
Electron Microscopy Structural Insights into CPAP Oligomeric Behavior: A Plausible Assembly Process of a Supramolecular Scaffold of the Centrosome.
1. Front Mol Biosci - published April 12, 2017
2. Alvarez-Cabrera AL, Delgado S, Gil-Carton D, Mortuza GB, Montoya G, Sorzano CO, Tang TK, Carazo JM
Giant viruses with an expanded complement of translation system components.
1. Science - published April 7, 2017
2. Schulz F, Yutin N, Ivanova NN, Ortega DR, Lee TK, Vierheilig J, Daims H, Horn M, Wagner M, Jensen GJ, Kyrpides NC, Koonin EV, Woyke T
Characterization of ATP7A missense mutants suggests a correlation between intracellular trafficking and severity of Menkes disease.
1. Sci Rep - published April 7, 2017
2. Skjørringe T, Amstrup Pedersen P, Salling Thorborg S, Nissen P, Gourdon P, Birk Møller L
Taxonomy of the order Mononegavirales: update 2017.
1. Arch Virol - published April 7, 2017
2. Amarasinghe GK, Bào Y, Basler CF, Bavari S, Beer M, Bejerman N, Blasdell KR, Bochnowski A, Briese T, Bukreyev A, Calisher CH, Chandran K, Collins PL, Dietzgen RG, Dolnik O, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Fang Q, Formenty P, Fouchier RA, Ghedin E, Harding RM, Hewson R, Higgins CM, Hong J, Horie M, James AP, Jiāng D, Kobinger GP, Kondo H, Kurath G, Lamb RA, Lee B, Leroy EM, Li M, Maisner A, Mühlberger E, Netesov SV, Nowotny N, Patterson JL, Payne SL, Paweska JT, Pearson MN, Randall RE, Revill PA, Rima BK, Rota P, Rubbenstroth D, Schwemmle M, Smither SJ, Song Q, Stone DM, Takada A, Terregino C, Tesh RB, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Volchkov VE, Wahl-Jensen V, Walker PJ, Wang B, Wang D, Wang F, Wang LF, Werren JH, Whitfield AE, Yan Z, Ye G, Kuhn JH
D-Cysteine Ligands Control Metal Geometries within de Novo Designed Three-Stranded Coiled Coils.
1. Chemistry - published April 6, 2017
2. Pecoraro VL, Ruckthong L, Peacock AF, Pascoe CE, Hemmingsen L, Stuckey JA
Multidimensional Tracking of GPCR Signaling via Peroxidase-Catalyzed Proximity Labeling.
1. Cell - published April 6, 2017
2. Paek J, Kalocsay M, Staus DP, Wingler L, Pascolutti R, Paulo JA, Gygi SP, Kruse AC
Structural Basis of Protein Translocation by the Vps4-Vta1 AAA ATPase.
1. Elife - published April 5, 2017
2. Monroe N, Han H, Shen PS, Sundquist WI, Hill CP
Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody.
1. Sci Transl Med - published April 5, 2017
2. Mire CE, Geisbert JB, Borisevich V, Fenton KA, Agans KN, Flyak AI, Deer DJ, Steinkellner H, Bohorov O, Bohorova N, Goodman C, Hiatt A, Kim DH, Pauly MH, Velasco J, Whaley KJ, Crowe JE Jr, Zeitlin L, Geisbert TW
XTEND: Extending the depth of field in cryo soft X-ray tomography.
1. Sci Rep - published April 4, 2017
2. Otón J, Pereiro E, Conesa JJ, Chichón FJ, Luque D, Rodríguez JM, Pérez-Berná AJ, Sorzano CO, Klukowska J, Herman GT, Vargas J, Marabini R, Carrascosa JL, Carazo JM
Glutamate 52-β at the α/β Subunit Interface of E. coli Class Ia Ribonucleotide Reductase is essential for Conformational Gating of Radical Transfer.
1. J Biol Chem - published April 4, 2017
2. Lin Q, Parker MJ, Taguchi AT, Ravichandran K, Kim A, Kang G, Shao J, Drennan CL, Stubbe J
Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain.
1. Bioorg Med Chem Lett - published April 4, 2017
2. Spiliotopoulos D, Zhu J, Wamhoff EC, Deerain N, Marchand JR, Aretz J, Rademacher C, Caflisch A
The stem cell/cancer stem cell marker ALDH1A3 regulates the expression of the survival factor tissue transglutaminase, in mesenchymal glioma stem cells.
1. Oncotarget - published April 4, 2017
2. Sullivan KE, Rojas K, Cerione RA, Nakano I, Wilson KF
Conformational equilibria of light-activated rhodopsin in nanodiscs.
1. Proc Natl Acad Sci U S A - published April 3, 2017
2. Van Eps N, Caro LN, Morizumi T, Kusnetzow AK, Szczepek M, Hofmann KP, Bayburt TH, Sligar SG, Ernst OP, Hubbell WL
Targeted rescue of cancer-associated IDH1 mutant activity using an engineered synthetic antibody.
1. Sci Rep - published April 3, 2017
2. Rizk SS, Mukherjee S, Koide A, Koide S, Kossiakoff AA
Plasmodium falciparum erythrocyte-binding antigen 175 triggers a biophysical change in the red blood cell that facilitates invasion.
1. Proc Natl Acad Sci U S A - published April 3, 2017
2. Koch M, Wright KE, Otto O, Herbig M, Salinas ND, Tolia NH, Satchwell TJ, Guck J, Brooks NJ, Baum J
NEIL1 protects against aflatoxin-induced hepatocellular carcinoma in mice.
1. Proc Natl Acad Sci U S A - published April 3, 2017
2. Vartanian V, Minko IG, Chawanthayatham S, Egner PA, Lin YC, Earley LF, Makar R, Eng JR, Camp MT, Li L, Stone MP, Lasarev MR, Groopman JD, Croy RG, Essigmann JM, McCullough AK, Lloyd RS
Binding site density enables paralog-specific activity of SLM2 and Sam68 proteins in Neurexin2 AS4 splicing control.
1. Nucleic Acids Res - published April 2, 2017
2. Danilenko M, Dalgliesh C, Pagliarini V, Naro C, Ehrmann I, Feracci M, Kheirollahi-Chadegani M, Tyson-Capper A, Clowry GJ, Fort P, Dominguez C, Sette C, Elliott DJ
When Worlds Collide-Mechanisms at the Interface between Phosphorylation and Ubiquitination.
1. J Mol Biol - published April 2, 2017
2. Filipčík P, Curry JR, Mace PD
Resolving the cofactor-binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1.
1. J Biol Chem - published April 2, 2017
2. Christensen EM, Patel SM, Korasick DA, Campbell AC, Krause KL, Becker DF, Tanner JJ
Structural and functional characterization of Caenorhabditis elegans α-catenin reveals constitutive binding to β-catenin and F-actin.
1. J Biol Chem - published April 2, 2017
2. Kang H, Bang I, Jin KS, Lee B, Lee J, Shao X, Heier JA, Kwiatkowski AV, Nelson WJ, Hardin J, Weis WI, Choi HJ
Structure-Energy Relationships of Halogen Bonds in Proteins.
1. Biochemistry - published April 2, 2017
2. Scholfield MR, Ford MC, Carlsson AC, Butta H, Mehl RA, Ho PS
The Uncommon Enzymology of Cis-Acyltransferase Assembly Lines.
1. Chem Rev - published April 2, 2017
2. Keatinge-Clay AT
Computational Design of the Tiam1 PDZ Domain and Its Ligand Binding.
1. J Chem Theory Comput - published April 2, 2017
2. Mignon D, Panel N, Chen X, Fuentes EJ, Simonson T
Nucleic acid detection with CRISPR-Cas13a/C2c2.
1. Science - published April 2, 2017
2. Gootenberg JS, Abudayyeh OO, Lee JW, Essletzbichler P, Dy AJ, Joung J, Verdine V, Donghia N, Daringer NM, Freije CA, Myhrvold C, Bhattacharyya RP, Livny J, Regev A, Koonin EV, Hung DT, Sabeti PC, Collins JJ, Zhang F
Crystal structures of the NO sensor NsrR reveal how its iron-sulfur cluster modulates DNA binding.
1. Nat Commun - published April 2, 2017
2. Volbeda A, Dodd EL, Darnault C, Crack JC, Renoux O, Hutchings MI, Le Brun NE, Fontecilla-Camps JC
Cryo-EM Structure of the Open Human Ether-à-go-go-Related K+ Channel hERG.
1. Cell - published April 2, 2017
2. Wang W, MacKinnon R
Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
1. Mol Cell - published April 2, 2017
2. Swarts DC, van der Oost J, Jinek M
Structural and Functional Analysis of a β2-Adrenergic Receptor Complex with GRK5.
1. Cell - published April 2, 2017
2. Komolov KE, Du Y, Duc NM, Betz RM, Rodrigues JPGLM, Leib RD, Patra D, Skiniotis G, Adams CM, Dror RO, Chung KY, Kobilka BK, Benovic JL
Variation in GP decisions on antihypertensive treatment in oldest-old and frail individuals across 29 countries.
1. BMC Geriatr - published April 2, 2017
2. Streit S, Verschoor M, Rodondi N, Bonfim D, Burman RA, Collins C, Biljana GK, Gintere S, Gómez Bravo R, Hoffmann K, Iftode C, Johansen KL, Kerse N, Koskela TH, Peštić SK, Kurpas D, Mallen CD, Maisoneuve H, Merlo C, Mueller Y, Muth C, Šter MP, Petrazzuoli F, Rosemann T, Sattler M, Švadlenková Z, Tatsioni A, Thulesius H, Tkachenko V, Torzsa P, Tsopra R, Canan T, Viegas RPA, Vinker S, de Waal MWM, Zeller A, Gussekloo J, Poortvliet RKE
Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator.
1. Sci Rep - published April 2, 2017
2. Schlundt A, Buchner S, Janowski R, Heydenreich T, Heermann R, Lassak J, Geerlof A, Stehle R, Niessing D, Jung K, Sattler M
Phase-plate cryo-EM structure of a class B GPCR-G-protein complex.
1. Nature - published April 2, 2017
2. Liang YL, Khoshouei M, Radjainia M, Zhang Y, Glukhova A, Tarrasch J, Thal DM, Furness SGB, Christopoulos G, Coudrat T, Danev R, Baumeister W, Miller LJ, Christopoulos A, Kobilka BK, Wootten D, Skiniotis G, Sexton PM
Structural Insights into the Mechanism of Group II Intron Splicing.
1. Trends Biochem Sci - published April 2, 2017
2. Zhao C, Pyle AM
Production, characterization, and assessment of a stable analog of the response regulator CheY-phosphate from Thermotoga maritima.
1. Protein Sci - published April 2, 2017
2. Beyersdorf MS, Sircar R, Lookadoo DB, Bottone C, Lynch MJ, Crane BR, Halkides CJ
Structure of a protective epitope of group B Streptococcus type III capsular polysaccharide.
1. Proc Natl Acad Sci U S A - published April 2, 2017
2. Carboni F, Adamo R, Fabbrini M, De Ricco R, Cattaneo V, Brogioni B, Veggi D, Pinto V, Passalacqua I, Oldrini D, Rappuoli R, Malito E, Margarit IYR, Berti F
Structure and energetics of pairwise interactions between proteasome subunits RPN2, RPN13, and ubiquitin clarify a substrate recruitment mechanism.
1. J Biol Chem - published April 2, 2017
2. VanderLinden RT, Hemmis CW, Yao T, Robinson H, Hill CP
Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation.
1. Cell Rep - published April 2, 2017
2. Zhou T, Doria-Rose NA, Cheng C, Stewart-Jones GBE, Chuang GY, Chambers M, Druz A, Geng H, McKee K, Kwon YD, O'Dell S, Sastry M, Schmidt SD, Xu K, Chen L, Chen RE, Louder MK, Pancera M, Wanninger TG, Zhang B, Zheng A, Farney SK, Foulds KE, Georgiev IS, Joyce MG, Lemmin T, Narpala S, Rawi R, Soto C, Todd JP, Shen CH, Tsybovsky Y, Yang Y, Zhao P, Haynes BF, Stamatatos L, Tiemeyer M, Wells L, Scorpio DG, Shapiro L, McDermott AB, Mascola JR, Kwong PD
Bim gene dosage is critical in modulating nephron progenitor survival in the absence of microRNAs during kidney development.
1. FASEB J - published April 2, 2017
2. Cerqueira DM, Bodnar AJ, Phua YL, Freer R, Hemker SL, Walensky LD, Hukriede NA, Ho J
Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity.
1. Nat Commun - published April 2, 2017
2. Kouno T, Silvas TV, Hilbert BJ, Shandilya SMD, Bohn MF, Kelch BA, Royer WE, Somasundaran M, Kurt Yilmaz N, Matsuo H, Schiffer CA
Structural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complex.
1. Nucleic Acids Res - published April 2, 2017
2. Aceytuno RD, Piett CG, Havali-Shahriari Z, Edwards RA, Rey M, Ye R, Javed F, Fang S, Mani R, Weinfeld M, Hammel M, Tainer JA, Schriemer DC, Lees-Miller SP, Glover JNM
Differential manipulation of arrestin-3 binding to basal and agonist-activated G protein-coupled receptors.
1. Cell Signal - published April 2, 2017
2. Prokop S, Perry NA, Vishnivetskiy SA, Toth AD, Inoue A, Milligan G, Iverson TM, Hunyady L, Gurevich VV
Ska3 Phosphorylated by Cdk1 Binds Ndc80 and Recruits Ska to Kinetochores to Promote Mitotic Progression.
1. Curr Biol - published April 2, 2017
2. Zhang Q, Sivakumar S, Chen Y, Gao H, Yang L, Yuan Z, Yu H, Liu H
Reevaluation of fenpropimorph as a σ receptor ligand: Structure-affinity relationship studies at human σ1 receptors.
1. Bioorg Med Chem Lett - published April 2, 2017
2. Sguazzini E, Schmidt HR, Iyer KA, Kruse AC, Dukat M
Synthesis and pharmacological evaluation of neurosteroid photoaffinity ligands.
1. Eur J Med Chem - published April 2, 2017
2. Savechenkov PY, Chiara DC, Desai R, Stern AT, Zhou X, Ziemba AM, Szabo AL, Zhang Y, Cohen JB, Forman SA, Miller KW, Bruzik KS
¹H, ¹⁵N and ¹³C resonance assignments for free and IEEVD peptide-bound forms of the tetratricopeptide repeat domain from the human E3 ubiquitin ligase CHIP.
1. Biomol NMR Assign - published April 1, 2017
2. Zhang H, McGlone C, Mannion MM, Page RC
An M2-V27A channel blocker demonstrates potent in vitro and in vivo antiviral activities against amantadine-sensitive and -resistant influenza A viruses.
1. Antiviral Res - published April 1, 2017
2. Hu Y, Musharrafieh R, Ma C, Zhang J, Smee DF, DeGrado WF, Wang J
Uncovering oxysterol-binding protein (OSBP) as a target of the anti-enteroviral compound TTP-8307.
1. Antiviral Res - published April 1, 2017
2. Albulescu L, Bigay J, Biswas B, Weber-Boyvat M, Dorobantu CM, Delang L, van der Schaar HM, Jung YS, Neyts J, Olkkonen VM, van Kuppeveld FJM, Strating JRPM
Targeting Class I Histone Deacetylases in a "Complex" Environment.
1. Trends Pharmacol Sci - published April 1, 2017
2. Millard CJ, Watson PJ, Fairall L, Schwabe JWR
Monoclonal Antibodies Against the Staphylococcus aureus Bicomponent Leukotoxin AB Isolated Following Invasive Human Infection Reveal Diverse Binding and Modes of Action.
1. J Infect Dis - published April 1, 2017
2. Thomsen IP, Sapparapu G, James DBA, Cassat JE, Nagarsheth M, Kose N, Putnam N, Boguslawski KM, Jones LS, Wood JB, Creech CB, Torres VJ, Crowe JE Jr
Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.
1. Chemistry - published April 1, 2017
2. D'Annessa I, Sattin S, Tao J, Pennati M, Sànchez-Martìn C, Moroni E, Rasola A, Zaffaroni N, Agard DA, Bernardi A, Colombo G
Prolactin Receptor-Mediated Internalization of Imaging Agents Detects Epithelial Ovarian Cancer with Enhanced Sensitivity and Specificity.
1. Cancer Res - published April 1, 2017
2. Sundaram KM, Zhang Y, Mitra AK, Kouadio JK, Gwin K, Kossiakoff AA, Roman BB, Lengyel E, Piccirilli JA
Lineage-specific proteins essential for endocytosis in trypanosomes.
1. J Cell Sci - published April 1, 2017
2. Manna PT, Obado SO, Boehm C, Gadelha C, Sali A, Chait BT, Rout MP, Field MC
Fam20C is under the control of sphingolipid signaling in human cell lines.
1. FEBS J - published April 1, 2017
2. Cozza G, Salvi M, Tagliabracci VS, Pinna LA
MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy.
1. Nat Methods - published April 1, 2017
2. Zheng SQ, Palovcak E, Armache JP, Verba KA, Cheng Y, Agard DA
switchSENSE: A new technology to study protein-RNA interactions.
1. Methods - published April 1, 2017
2. Cléry A, Sohier TJM, Welte T, Langer A, Allain FHT
Multiplex Substrate Profiling by Mass Spectrometry for Kinases as a Method for Revealing Quantitative Substrate Motifs.
1. Anal Chem - published April 1, 2017
2. Meyer NO, O'Donoghue AJ, Schulze-Gahmen U, Ravalin M, Moss SM, Winter MB, Knudsen GM, Craik CS
Polyketide Synthase Modules Redefined.
1. Angew Chem Int Ed Engl - published April 1, 2017
2. Keatinge-Clay AT
Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening.
1. Nat Protoc - published April 1, 2017
2. Joung J, Konermann S, Gootenberg JS, Abudayyeh OO, Platt RJ, Brigham MD, Sanjana NE, Zhang F
Targeted Diazotransfer Reagents Enable Selective Modification of Proteins with Azides.
1. Bioconjug Chem - published April 1, 2017
2. Lohse J, Swier LJYM, Oudshoorn RC, Médard G, Kuster B, Slotboom DJ, Witte MD
Interdependence of Inhibitor Recognition in HIV-1 Protease.
1. J Chem Theory Comput - published April 1, 2017
2. Paulsen JL, Leidner F, Ragland DA, Kurt Yilmaz N, Schiffer CA
Relationships between hydrogen bonds and halogen bonds in biological systems.
1. Acta Crystallogr B Struct Sci Cryst Eng Mater - published April 1, 2017
2. Rowe RK, Ho PS
Low-dose fixed-target serial synchrotron crystallography.
1. Acta Crystallogr D Struct Biol - published April 1, 2017
2. Owen RL, Axford D, Sherrell DA, Kuo A, Ernst OP, Schulz EC, Miller RJ, Mueller-Werkmeister HM
Crystal structure and RNA-binding properties of an Hfq homolog from the deep-branching Aquificae: conservation of the lateral RNA-binding mode.
1. Acta Crystallogr D Struct Biol - published April 1, 2017
2. Stanek KA, Patterson-West J, Randolph PS, Mura C
Dissecting random and systematic differences between noisy composite data sets.
1. Acta Crystallogr D Struct Biol - published April 1, 2017
2. Diederichs K
Substrate-Dependent Cleavage Site Selection by Unconventional Radical S-Adenosylmethionine Enzymes in Diphthamide Biosynthesis.
1. J Am Chem Soc - published April 1, 2017
2. Dong M, Horitani M, Dzikovski B, Freed JH, Ealick SE, Hoffman BM, Lin H
Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication.
1. EMBO Rep - published April 1, 2017
2. Hanke L, Schmidt FI, Knockenhauer KE, Morin B, Whelan SP, Schwartz TU, Ploegh HL
A clinical and mechanistic study of topical borneol-induced analgesia.
1. EMBO Mol Med - published April 1, 2017
2. Wang S, Zhang D, Hu J, Jia Q, Xu W, Su D, Song H, Xu Z, Cui J, Zhou M, Yang J, Xiao J
Structure of a DNA glycosylase that unhooks interstrand cross-links.
1. Proc Natl Acad Sci U S A - published April 1, 2017
2. Mullins EA, Warren GM, Bradley NP, Eichman BF
The structural basis for the functional comparability of Factor VIII and the long-acting variant recombinant Factor VIII Fc fusion protein.
1. J Thromb Haemost - published April 1, 2017
2. Leksa NC, Chiu PL, Bou-Assaf GM, Quan C, Liu Z, Goodman AB, Chambers MG, Tsutakawa SE, Hammel M, Peters RT, Walz T, Kulman JD
Dimerization of Tie2 mediated by its membrane-proximal FNIII domains.
1. Proc Natl Acad Sci U S A - published April 1, 2017
2. Moore JO, Lemmon MA, Ferguson KM
Antigenicity-defined conformations of an extremely neutralization-resistant HIV-1 envelope spike.
1. Proc Natl Acad Sci U S A - published April 1, 2017
2. Cai Y, Karaca-Griffin S, Chen J, Tian S, Fredette N, Linton CE, Rits-Volloch S, Lu J, Wagh K, Theiler J, Korber B, Seaman MS, Harrison SC, Carfi A, Chen B
Transcriptional repression of frequency by the IEC-1-INO80 complex is required for normal Neurospora circadian clock function.
1. PLoS Genet - published April 1, 2017
2. Gai K, Cao X, Dong Q, Ding Z, Wei Y, Liu Y, Liu X, He Q
The chemical basis for electrical signaling.
1. Nat Chem Biol - published April 1, 2017
2. Catterall WA, Wisedchaisri G, Zheng N
SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation.
1. Elife - published April 1, 2017
2. Zhang X, Spiegelman NA, Nelson OD, Jing H, Lin H
Toll-like receptor 7 deficiency protects apolipoprotein E-deficient mice from diet-induced atherosclerosis.
1. Sci Rep - published April 1, 2017
2. Liu CL, Santos MM, Fernandes C, Liao M, Iamarene K, Zhang JY, Sukhova GK, Shi GP
Stability and Conformation of a Chemoreceptor HAMP Domain Chimera Correlates with Signaling Properties.
1. Biophys J - published April 1, 2017
2. Sukomon N, Widom J, Borbat PP, Freed JH, Crane BR
Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits.
1. Cell Rep - published April 1, 2017
2. Platt RJ, Zhou Y, Slaymaker IM, Shetty AS, Weisbach NR, Kim JA, Sharma J, Desai M, Sood S, Kempton HR, Crabtree GR, Feng G, Zhang F
Interplay of buried histidine protonation and protein stability in prion misfolding.
1. Sci Rep - published April 1, 2017
2. Malevanets A, Chong PA, Hansen DF, Rizk P, Sun Y, Lin H, Muhandiram R, Chakrabartty A, Kay LE, Forman-Kay JD, Wodak SJ
Architecture of a transcribing-translating expressome.
1. Science - published April 1, 2017
2. Kohler R, Mooney RA, Mills DJ, Landick R, Cramer P
Structural Basis of Apoptosis Inhibition by the Fowlpox Virus Protein FPV039.
1. J Biol Chem - published April 1, 2017
2. Anasir MI, Caria S, Skinner MA, Kvansakul M
Direct Antimicrobial Activity of IFN-β.
1. J Immunol - published April 1, 2017
2. Kaplan A, Lee MW, Wolf AJ, Limon JJ, Becker CA, Ding M, Murali R, Lee EY, Liu GY, Wong GCL, Underhill DM
Split tasks of asymmetric nucleotide-binding sites in the heterodimeric ABC exporter EfrCD.
1. FEBS J - published April 1, 2017
2. Hürlimann LM, Hohl M, Seeger MA
Integrin extension enables ultrasensitive regulation by cytoskeletal force.
1. Proc Natl Acad Sci U S A - published April 1, 2017
2. Li J, Springer TA
Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.
1. Angew Chem Int Ed Engl - published April 1, 2017
2. Remillard D, Buckley DL, Paulk J, Brien GL, Sonnett M, Seo HS, Dastierdi S, Wühr M, Dhe-Paganon S, Armstrong SA, Bradner JE
The Cac2 subunit is essential for productive histone binding and nucleosome assembly in CAF-1.
1. Sci Rep - published April 1, 2017
2. Mattiroli F, Gu Y, Balsbaugh JL, Ahn NG, Luger K
Flexibility and Design: Conformational Heterogeneity along the Evolutionary Trajectory of a Redesigned Ubiquitin.
1. Structure - published April 1, 2017
2. Biel JT, Thompson MC, Cunningham CN, Corn JE, Fraser JS
Structure of the hexagonal surface layer on Caulobacter crescentus cells.
1. Nat Microbiol - published April 1, 2017
2. Bharat TAM, Kureisaite-Ciziene D, Hardy GG, Yu EW, Devant JM, Hagen WJH, Brun YV, Briggs JAG, Löwe J
Current carried by the Slc26 family member prestin does not flow through the transporter pathway.
1. Sci Rep - published April 1, 2017
2. Bai JP, Moeini-Naghani I, Zhong S, Li FY, Bian S, Sigworth FJ, Santos-Sacchi J, Navaratnam D
A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure.
1. Immunity - published April 1, 2017
2. Lee JH, Andrabi R, Su CY, Yasmeen A, Julien JP, Kong L, Wu NC, McBride R, Sok D, Pauthner M, Cottrell CA, Nieusma T, Blattner C, Paulson JC, Klasse PJ, Wilson IA, Burton DR, Ward AB
Modulation of TMEM16A Channel Activity by the Von Willebrand Factor Type A (VWA) domain of the Calcium-Activated Chloride Channel Regulator 1 (CLCA1).
1. J Biol Chem - published April 1, 2017
2. Sala-Rabanal M, Yurtsever Z, Berry KN, Nichols CG, Brett TJ
Treating Flu with Skin of Frog.
1. Immunity - published April 1, 2017
2. Crowe JE Jr
Erratum to: CcpNmr AnalysisAssign: a flexible platform for integrated NMR analysis.
1. J Biomol NMR - published April 1, 2017
2. Skinner SP, Fogh RH, Boucher W, Ragan TJ, Mureddu LG, Vuister GW
Engineering a high-affinity peptide binding site into the anti-CEA mAb M5A.
1. Protein Eng Des Sel - published April 1, 2017
2. Zer C, Avery KN, Meyer K, Goodstein L, Bzymek KP, Singh G, Williams JC
TREM2-ligand interactions in health and disease.
1. J Mol Biol - published April 1, 2017
2. Kober DL, Brett TJ
Clostridium difficile toxin glucosyltransferase domains in complex with a non-hydrolyzable UDP-glucose analogue.
1. J Struct Biol - published April 1, 2017
2. Alvin JW, Lacy DB
Unraveling self-assembly pathways of the 468-kDa proteolytic machine TET2.
1. Sci Adv - published April 1, 2017
2. Macek P, Kerfah R, Erba EB, Crublet E, Moriscot C, Schoehn G, Amero C, Boisbouvier J
Mechanism of Vps4 hexamer function revealed by cryo-EM.
1. Sci Adv - published April 1, 2017
2. Su M, Guo EZ, Ding X, Li Y, Tarrasch JT, Brooks CL 3rd, Xu Z, Skiniotis G
Structural and biochemical differences between the Notch and the amyloid precursor protein transmembrane domains.
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