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151 Member Publications for September 2016

Binding Sites for Acylated Trehalose Analogs of Glycolipid Ligands on an Extended Carbohydrate Recognition Domain of the Macrophage Receptor Mincle.
1. J. Biol. Chem. - published September 30, 2016
2. Feinberg H, Rambaruth ND, Jégouzo SA, Jacobsen KM, Djurhuus R, Poulsen TB, Weis WI, Taylor ME, Drickamer K
Brucella abortus ΔrpoE1 confers protective immunity against wild type challenge in a mouse model of brucellosis.
1. Vaccine - published September 30, 2016
2. Willett JW, Herrou J, Czyż DM, Cheng JX, Crosson S
D3R grand challenge 2015: Evaluation of protein-ligand pose and affinity predictions.
1. J. Comput. Aided Mol. Des. - published September 30, 2016
2. Gathiaka S, Liu S, Chiu M, Yang H, Stuckey JA, Kang YN, Delproposto J, Kubish G, Dunbar JB, Carlson HA, Burley SK, Walters WP, Amaro RE, Feher VA, Gilson MK
Mechanisms of Insertion of dCTP and dTTP Opposite the DNA lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase η.
1. J. Biol. Chem. - published September 30, 2016
2. Patra A, Zhang Q, Guengerich FP, Egli M
Nuclear Exodus: Herpesviruses Lead the Way.
1. Annu Rev Virol - published September 29, 2016
2. Bigalke JM, Heldwein EE
RNA polymerase II pausing modulates hematopoietic stem cell emergence in zebrafish.
1. Blood - published September 29, 2016
2. Yang Q, Liu X, Zhou T, Cook J, Nguyen K, Bai X
Acinetobacter baumannii Coordinates Urea Metabolism with Metal Import To Resist Host-Mediated Metal Limitation.
1. MBio - published September 29, 2016
2. Juttukonda LJ, Chazin WJ, Skaar EP
Investigating the Role of Large-Scale Domain Dynamics in Protein-Protein Interactions.
1. Front Mol Biosci - published September 29, 2016
2. Delaforge E, Milles S, Huang JR, Bouvier D, Jensen MR, Sattler M, Hart DJ, Blackledge M
Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up.
1. Ann. Oncol. - published September 29, 2016
2. Kadara H, Choi M, Zhang J, Cuentas EP, Canales JR, Gaffney SG, Zhao Z, Behrens C, Fujimoto J, Chow C, Yoo Y, Kalhor N, Moran C, Rimm D, Swisher S, Gibbons DL, Heymach J, Kaftan E, Townsend JP, Lynch TJ, Schlessinger J, Lee J, Lifton RP, Wistuba II, Herbst RS
Mutation profiles in early-stage lung squamous cell carcinoma with clinical follow-up and correlation with markers of immune function.
1. Ann. Oncol. - published September 29, 2016
2. Choi M, Kadara H, Zhang J, Cuentas EP, Canales JR, Gaffney SG, Zhao Z, Behrens C, Fujimoto J, Chow C, Kim K, Kalhor N, Moran C, Rimm D, Swisher S, Gibbons DL, Heymach J, Kaftan E, Townsend JP, Lynch TJ, Schlessinger J, Lee JJ, Lifton RP, Herbst RS, Wistuba II
Blue protein with red fluorescence.
1. Proc. Natl. Acad. Sci. U.S.A. - published September 29, 2016
2. Ghosh S, Yu CL, Ferraro DJ, Sudha S, Pal SK, Schaefer WF, Gibson DT, Ramaswamy S
De novo phasing with X-ray laser reveals mosquito larvicide BinAB structure.
1. Nature - published September 28, 2016
2. Colletier JP, Sawaya MR, Gingery M, Rodriguez JA, Cascio D, Brewster AS, Michels-Clark T, Hice RH, Coquelle N, Boutet S, Williams GJ, Messerschmidt M, DePonte DP, Sierra RG, Laksmono H, Koglin JE, Hunter MS, Park HW, Uervirojnangkoorn M, Bideshi DK, Brunger AT, Federici BA, Sauter NK, Eisenberg DS
A ring-shaped conduit connects the mother cell and forespore during sporulation in Bacillus subtilis.
1. Proc. Natl. Acad. Sci. U.S.A. - published September 28, 2016
2. Rodrigues CD, Henry X, Neumann E, Kurauskas V, Bellard L, Fichou Y, Schanda P, Schoehn G, Rudner DZ, Morlot C
Treatment of ear and bone disease in the Phex mouse mutant with dietary supplementation.
1. Am J Otolaryngol - published September 28, 2016
2. Wick CC, Lin SJ, Yu H, Megerian CA, Zheng QY
While the Revolution Will Not Be Crystallized, Biochemistry Reigns Supreme.
1. Protein Sci. - published September 27, 2016
2. Takizawa Y, Binshtein E, Erwin AL, Pyburn TM, Mittendorf KF, Ohi MD
A Guide to the 3D Structure of the Ryanodine Receptor Type 1 by cryoEM.
1. Protein Sci. - published September 27, 2016
2. Samsó M
Discovery of Allosteric and Selective Inhibitors of Inorganic Pyrophosphatase from Mycobacterium tuberculosis.
1. ACS Chem. Biol. - published September 26, 2016
2. Pang AH, Garzan A, Larsen MJ, McQuade TJ, Garneau-Tsodikova S, Tsodikov OV
Automated structure refinement of macromolecular assemblies from cryo-EM maps using Rosetta.
1. Elife - published September 26, 2016
2. Wang RY, Song Y, Barad BA, Cheng Y, Fraser JS, DiMaio F
Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection.
1. Nat. Med. - published September 26, 2016
2. Zackular JP, Moore JL, Jordan AT, Juttukonda LJ, Noto MJ, Nicholson MR, Crews JD, Semler MW, Zhang Y, Ware LB, Washington MK, Chazin WJ, Caprioli RM, Skaar EP
MeCP2 and histone deacetylases 1 and 2 in dorsal striatum collectively suppress repetitive behaviors.
1. Nat. Neurosci. - published September 26, 2016
2. Mahgoub M, Adachi M, Suzuki K, Liu X, Kavalali ET, Chahrour MH, Monteggia LM
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection.
1. Nature - published September 26, 2016
2. East-Seletsky A, O'Connell MR, Knight SC, Burstein D, Cate JH, Tjian R, Doudna JA
Dual interaction of the Hsp70 J-protein cochaperone Zuotin with the 40S and 60S ribosomal subunits.
1. Nat. Struct. Mol. Biol. - published September 26, 2016
2. Lee K, Sharma R, Shrestha OK, Bingman CA, Craig EA
Membrane fission by dynamin: what we know and what we need to know.
1. EMBO J. - published September 26, 2016
2. Antonny B, Burd C, De Camilli P, Chen E, Daumke O, Faelber K, Ford M, Frolov VA, Frost A, Hinshaw JE, Kirchhausen T, Kozlov MM, Lenz M, Low HH, McMahon H, Merrifield C, Pollard TD, Robinson PJ, Roux A, Schmid S
Solution Structure of the Cuz1 AN1 Zinc Finger Domain: An Exposed LDFLP Motif Defines a Subfamily of AN1 Proteins.
1. PLoS ONE - published September 24, 2016
2. Sun ZJ, Bhanu MK, Allan MG, Arthanari H, Wagner G, Hanna J
Role of E2- RING interactions in governing RNF4-mediated substrate ubiquitination.
1. J. Mol. Biol. - published September 24, 2016
2. DiBello A, Datta AB, Zhang X, Wolberger C
Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase.
1. Cell Chem Biol - published September 23, 2016
2. Bodea S, Funk MA, Balskus EP, Drennan CL
Cryo-Electron Tomography: Can it Reveal the Molecular Sociology of Cells in Atomic Detail?
1. Trends Cell Biol. - published September 23, 2016
2. Beck M, Baumeister W
An Adaptive Mutation in Enterococcus faecium LiaR Associated with Antimicrobial Peptide Resistance Mimics Phosphorylation and Stabilizes LiaR in an Activated State.
1. J. Mol. Biol. - published September 23, 2016
2. Davlieva M, Tovar-Yanez A, DeBruler K, Leonard PG, Zianni MR, Arias CA, Shamoo Y
Selective Covalent Targeting of Anti-Apoptotic BFL-1 by Cysteine-Reactive Stapled Peptide Inhibitors.
1. Cell Chem Biol - published September 22, 2016
2. Huhn AJ, Guerra RM, Harvey EP, Bird GH, Walensky LD
Selective targeting of IL-2 to NKG2D bearing cells for improved immunotherapy.
1. Nat Commun - published September 22, 2016
2. Ghasemi R, Lazear E, Wang X, Arefanian S, Zheleznyak A, Carreno BM, Higashikubo R, Gelman AE, Kreisel D, Fremont DH, Krupnick AS
The apo-structure of the leucine sensor Sestrin2 is still elusive.
1. Sci Signal - published September 22, 2016
2. Saxton RA, Knockenhauer KE, Schwartz TU, Sabatini DM
Dengue Protease Substrate Recognition: Binding of the Prime Side.
1. ACS Infect Dis - published September 22, 2016
2. Lin KH, Nalivaika EA, Prachanronarong KL, Yilmaz NK, Schiffer CA
Structural Basis for Gating and Activation of RyR1.
1. Cell - published September 22, 2016
2. des Georges A, Clarke OB, Zalk R, Yuan Q, Condon KJ, Grassucci RA, Hendrickson WA, Marks AR, Frank J
Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains.
1. Neuron - published September 21, 2016
2. Salzman GS, Ackerman SD, Ding C, Koide A, Leon K, Luo R, Stoveken HM, Fernandez CG, Tall GG, Piao X, Monk KR, Koide S, Araç D
Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition.
1. J. Mol. Biol. - published September 21, 2016
2. Reichen C, Hansen S, Forzani C, Honegger A, Fleishman SJ, Zhou T, Parmeggiani F, Ernst P, Madhurantakam C, Ewald C, Mittl PR, Zerbe O, Baker D, Caflisch A, Plückthun A
Cortical dynamics during cell motility are regulated by CRL3(KLHL21) E3 ubiquitin ligase.
1. Nat Commun - published September 20, 2016
2. Courtheoux T, Enchev RI, Lampert F, Gerez J, Beck J, Picotti P, Sumara I, Peter M
Costimulatory Effects of an Immunodominant Parasite Antigen Paradoxically Prevent Induction of Optimal CD8 T Cell Protective Immunity.
1. PLoS Pathog. - published September 20, 2016
2. Eickhoff CS, Zhang X, Vasconcelos JR, Motz RG, Sullivan NL, O'Shea K, Pozzi N, Gohara DW, Blase JR, Di Cera E, Hoft DF
Full-length model of the human galectin-4 and insights into dynamics of inter-domain communication.
1. Sci Rep - published September 20, 2016
2. Rustiguel JK, Soares RO, Meisburger SP, Davis KM, Malzbender KL, Ando N, Dias-Baruffi M, Nonato MC
Molecular basis of sidekick-mediated cell-cell adhesion and specificity.
1. Elife - published September 19, 2016
2. Goodman KM, Yamagata M, Jin X, Mannepalli S, Katsamba PS, Ahlsén G, Sergeeva AP, Honig B, Sanes JR, Shapiro L
Structural, super-resolution microscopy analysis of paraspeckle nuclear body organization.
1. J. Cell Biol. - published September 19, 2016
2. West JA, Mito M, Kurosaka S, Takumi T, Tanegashima C, Chujo T, Yanaka K, Kingston RE, Hirose T, Bond C, Fox A, Nakagawa S
Antibody Prophylaxis Against Dengue Virus 2 Infection in Non-Human Primates.
1. Am. J. Trop. Med. Hyg. - published September 19, 2016
2. Simmons M, Putnak R, Sun P, Burgess T, Marasco WA
Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization.
1. Proc. Natl. Acad. Sci. U.S.A. - published September 19, 2016
2. Kvansakul M, Lay FT, Adda CG, Veneer PK, Baxter AA, Phan TK, Poon IK, Hulett MD
Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED.
1. Proc. Natl. Acad. Sci. U.S.A. - published September 19, 2016
2. Sawaya MR, Rodriguez J, Cascio D, Collazo MJ, Shi D, Reyes FE, Hattne J, Gonen T, Eisenberg DS
Crystal structure of HLA-B*5801, a protective HLA allele for HIV-1 infection.
1. Protein Cell - published September 18, 2016
2. Li X, Lamothe PA, Ng R, Xu S, Teng M, Walker BD, Wang JH
Type IV Pilus Alignment Subcomplex Proteins PilN and PilO Form Homo- and Heterodimers in Vivo.
1. J. Biol. Chem. - published September 16, 2016
2. Leighton TL, Yong DH, Howell PL, Burrows LL
Specific Lipid Binding of Membrane Proteins in Detergent Micelles Characterized by NMR and Molecular Dynamics.
1. Biochemistry - published September 16, 2016
2. Zhao L, Wang S, Run C, OuYang B, Chou JJ
Methods to Purify and Assay Secretory Pathway Kinases.
1. Methods Mol Biol - published September 16, 2016
2. Tagliabracci VS, Wen J, Xiao J
Analysis of Arf1 GTPase-Dependent Membrane Binding and Remodeling Using the Exomer Secretory Vesicle Cargo Adaptor.
1. Methods Mol. Biol. - published September 16, 2016
2. Paczkowski JE, Fromme JC
dMM-PBSA: A New HADDOCK Scoring Function for Protein-Peptide Docking.
1. Front Mol Biosci - published September 16, 2016
2. Spiliotopoulos D, Kastritis PL, Melquiond AS, Bonvin AM, Musco G, Rocchia W, Spitaleri A
Heterodimerization of Kinesin-2 KIF3AB Modulates Entry into the Processive Run.
1. J. Biol. Chem. - published September 16, 2016
2. Albracht CD, Guzik-Lendrum S, Rayment I, Gilbert SP
Structural Biology and Evolution of the TGF-β Family.
1. Cold Spring Harb Perspect Biol - published September 16, 2016
2. Hinck AP, Mueller TD, Springer TA
Increasing rigor in NMR-based metabolomics through validated and open source tools.
1. Curr. Opin. Biotechnol. - published September 16, 2016
2. Eghbalnia HR, Romero PR, Westler WM, Baskaran K, Ulrich EL, Markley JL
Structural Insights into Conformation Differences between DNA/TNA and RNA/TNA Chimeric Duplexes.
1. Chembiochem - published September 15, 2016
2. Anosova I, Kowal EA, Sisco NJ, Sau S, Liao JY, Bala S, Rozners E, Egli M, Chaput JC, Van Horn WD
Ligand-based virtual screen for the discovery of novel M5 inhibitor chemotypes.
1. Bioorg. Med. Chem. Lett. - published September 15, 2016
2. Geanes AR, Cho HP, Nance KD, McGowan KM, Conn PJ, Jones CK, Meiler J, Lindsley CW
Thrombin Cleavage of Plasmodium falciparum Erythrocyte Membrane Protein 1 Inhibits Cytoadherence.
1. MBio - published September 15, 2016
2. Gillrie MR, Renaux B, Russell-Goldman E, Avril M, Brazier AJ, Mihara K, Di Cera E, Milner DA, Hollenberg MD, Smith JD, Ho M
Structural insights into the molecular mechanism of the m(6)A writer complex.
1. Elife - published September 15, 2016
2. Śledź P, Jinek M
The Crystal Structure of Peroxiredoxin Asp f3 Provides Mechanistic Insight into Oxidative Stress Resistance and Virulence of Aspergillus fumigatus.
1. Sci Rep - published September 15, 2016
2. Hillmann F, Bagramyan K, Straßburger M, Heinekamp T, Hong TB, Bzymek KP, Williams JC, Brakhage AA, Kalkum M
Structural basis for KCNE3 modulation of potassium recycling in epithelia.
1. Sci Adv - published September 15, 2016
2. Kroncke BM, Van Horn WD, Smith J, Kang C, Welch RC, Song Y, Nannemann DP, Taylor KC, Sisco NJ, George AL, Meiler J, Vanoye CG, Sanders CR
Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope.
1. Elife - published September 15, 2016
2. Otsuka S, Bui KH, Schorb M, Hossain MJ, Politi AZ, Koch B, Eltsov M, Beck M, Ellenberg J
Molecular basis of cobalamin-dependent RNA modification.
1. Nucleic Acids Res. - published September 15, 2016
2. Dowling DP, Miles ZD, Köhrer C, Maiocco SJ, Elliott SJ, Bandarian V, Drennan CL
A Crystallographic Examination of Predisposition versus Preorganization in de Novo Designed Metalloproteins.
1. J. Am. Chem. Soc. - published September 14, 2016
2. Ruckthong L, Zastrow ML, Stuckey JA, Pecoraro VL
Limits of RNA 2'-OH Mimicry by Fluorine: Crystal Structure of Bacillus halodurans RNase H Bound to a 2'-FRNA:DNA Hybrid.
1. Biochemistry - published September 14, 2016
2. Pallan PS, Prakash TP, de Leon AR, Egli M
From Biological Cilia to Artificial Flow Sensors: Biomimetic Soft Polymer Nanosensors with High Sensing Performance.
1. Sci Rep - published September 14, 2016
2. Asadnia M, Kottapalli AG, Karavitaki KD, Warkiani ME, Miao J, Corey DP, Triantafyllou M
Cooperation of the ER-shaping proteins atlastin, lunapark, and reticulons to generate a tubular membrane network.
1. Elife - published September 14, 2016
2. Wang S, Tukachinsky H, Romano FB, Rapoport TA
A broadly neutralizing anti-influenza antibody reveals ongoing capacity of haemagglutinin-specific memory B cells to evolve.
1. Nat Commun - published September 14, 2016
2. Fu Y, Zhang Z, Sheehan J, Avnir Y, Ridenour C, Sachnik T, Sun J, Hossain MJ, Chen LM, Zhu Q, Donis RO, Marasco WA
Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode.
1. Nature - published September 14, 2016
2. Wang D, Kon N, Lasso G, Jiang L, Leng W, Zhu WG, Qin J, Honig B, Gu W
Chronic myelogenous leukemia initiating cells require Polycomb group protein EZH2.
1. Cancer Discov - published September 14, 2016
2. Xie H, Peng C, Huang J, Li BE, Kim W, Smith EC, Fujiwara Y, Qi J, Cheloni G, Das PP, Nguyen M, Li S, Bradner JE, Orkin SH
Characterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex.
1. Autophagy - published September 14, 2016
2. Ohashi Y, Soler N, Ortegón MG, Zhang L, Kirsten ML, Perisic O, Masson GR, Burke JE, Jakobi AJ, Apostolakis AA, Johnson CM, Ohashi M, Ktistakis NT, Sachse C, Williams RL
An E2 gene infectious HCV library reveals growth adaptive mutations that modulate interactions with the scavenger receptor class B type I.
1. J. Virol. - published September 14, 2016
2. Zuiani A, Chen K, Schwarz MC, White JP, Luca VC, Fremont DH, Wang D, Evans MJ, Diamond MS
SUMO Modification Stabilizes Enterovirus 71 Polymerase 3D to Facilitate Viral Replication.
1. J. Virol. - published September 14, 2016
2. Liu Y, Zheng Z, Shu B, Meng J, Zhang Y, Zheng C, Ke X, Gong P, Hu Q, Wang H
Characterizing the Size and Composition of Saposin A Lipoprotein Picodiscs.
1. Anal. Chem. - published September 13, 2016
2. Li J, Richards MR, Bagal D, Campuzano ID, Kitova EN, Xiong ZJ, Privé GG, Klassen JS
Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate.
1. Proc. Natl. Acad. Sci. U.S.A. - published September 13, 2016
2. Maloney FP, Gerwick L, Gerwick WH, Sherman DH, Smith JL
BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression.
1. Cell Rep - published September 13, 2016
2. Zhu H, Bengsch F, Svoronos N, Rutkowski MR, Bitler BG, Allegrezza MJ, Yokoyama Y, Kossenkov AV, Bradner JE, Conejo-Garcia JR, Zhang R
Binding of RNA by the Nucleoproteins of Influenza Viruses A and B.
1. Viruses - published September 13, 2016
2. Labaronne A, Swale C, Monod A, Schoehn G, Crépin T, Ruigrok RW
A Study of Boratriazaroles: An Underdeveloped Class of Heterocycles.
1. J. Org. Chem. - published September 12, 2016
2. Liew SK, Holownia A, Tilley AJ, Carrera EI, Seferos DS, Yudin AK
An Integrated Model of RAF Inhibitor Action Predicts Inhibitor Activity against Oncogenic BRAF Signaling.
1. Cancer Cell - published September 12, 2016
2. Karoulia Z, Wu Y, Ahmed TA, Xin Q, Bollard J, Krepler C, Wu X, Zhang C, Bollag G, Herlyn M, Fagin JA, Lujambio A, Gavathiotis E, Poulikakos PI
How the glycosyltransferase OGT catalyzes amide bond cleavage.
1. Nat. Chem. Biol. - published September 12, 2016
2. Janetzko J, Trauger SA, Lazarus MB, Walker S
The Pentablock Amphiphilic Copolymer T1107 Prevents Aggregation of Denatured and Reduced Lysozyme.
1. Macromol Biosci - published September 12, 2016
2. Poellmann MJ, Sosnick TR, Meredith SC, Lee RC
Atypical modes of bacterial histidine kinase signaling.
1. Mol. Microbiol. - published September 12, 2016
2. Willett JW, Crosson S
Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site.
1. Nat. Struct. Mol. Biol. - published September 12, 2016
2. Gristick HB, von Boehmer L, West AP, Schamber M, Gazumyan A, Golijanin J, Seaman MS, Fätkenheuer G, Klein F, Nussenzweig MC, Bjorkman PJ
A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin.
1. Nat. Struct. Mol. Biol. - published September 12, 2016
2. Menting JG, Gajewiak J, MacRaild CA, Chou DH, Disotuar MM, Smith NA, Miller C, Erchegyi J, Rivier JE, Olivera BM, Forbes BE, Smith BJ, Norton RS, Safavi-Hemami H, Lawrence MC
Molecular Architecture of Contactin-associated Protein-like 2 (CNTNAP2) and its Interaction with Contactin 2 (CNTN2).
1. J. Biol. Chem. - published September 12, 2016
2. Lu Z, Reddy MV, Liu J, Kalichava A, Liu J, Zhang L, Chen F, Wang Y, Holthauzen LM, White MA, Seshadrinathan S, Zhong X, Ren G, Rudenko G
Selective RNA targeting and regulated signaling by RIG-I is controlled by coordination of RNA and ATP binding.
1. Nucleic Acids Res. - published September 12, 2016
2. Fitzgerald ME, Rawling DC, Potapova O, Ren X, Kohlway A, Pyle AM
Whither Ribosome Structure and Dynamics Research? (A Perspective).
1. J. Mol. Biol. - published September 11, 2016
2. Frank J
Engineering, Structure and Immunogenicity of the Human Metapneumovirus F Protein in the Postfusion Conformation.
1. PLoS Pathog. - published September 10, 2016
2. Más V, Rodriguez L, Olmedillas E, Cano O, Palomo C, Terrón MC, Luque D, Melero JA, McLellan JS
Self-regulation of BAX-induced cell death.
1. Oncotarget - published September 10, 2016
2. Reyna DE, Gavathiotis E
CAT7 and cat7l Long Non-coding RNAs Tune Polycomb Repressive Complex 1 Function during Human and Zebrafish Development.
1. J. Biol. Chem. - published September 9, 2016
2. Ray MK, Wiskow O, King MJ, Ismail N, Ergun A, Wang Y, Plys AJ, Davis CP, Kathrein K, Sadreyev R, Borowsky ML, Eggan K, Zon L, Galloway JL, Kingston RE
Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins.
1. EBioMedicine - published September 9, 2016
2. Richard J, Pacheco B, Gohain N, Veillette M, Ding S, Alsahafi N, Tolbert WD, Prévost J, Chapleau JP, Coutu M, Jia M, Brassard N, Park J, Courter JR, Melillo B, Martin L, Tremblay C, Hahn BH, Kaufmann DE, Wu X, Smith AB, Sodroski J, Pazgier M, Finzi A
Identification of Inhibitors for the DEDDh Family of Exonucleases and a Unique Inhibition Mechanism by Crystal Structure Analysis of CRN-4 Bound with 2-Morpholin-4-ylethanesulfonate (MES).
1. J Med Chem - published September 8, 2016
2. Huang KW, Hsu KC, Chu LY, Yang JM, Yuan HS, Hsiao YY
Structure-based discovery of opioid analgesics with reduced side effects.
1. Nature - published September 8, 2016
2. Manglik A, Lin H, Aryal DK, McCorvy JD, Dengler D, Corder G, Levit A, Kling RC, Bernat V, Hübner H, Huang XP, Sassano MF, Giguère PM, Löber S, Da Duan, Scherrer G, Kobilka BK, Gmeiner P, Roth BL, Shoichet BK
The Anti-sigma Factor RsiV Is a Bacterial Receptor for Lysozyme: Co-crystal Structure Determination and Demonstration That Binding of Lysozyme to RsiV Is Required for σV Activation.
1. PLoS Genet. - published September 8, 2016
2. Hastie JL, Williams KB, Bohr LL, Houtman JC, Gakhar L, Ellermeier CD
Applications of CRISPR technologies in research and beyond.
1. Nat. Biotechnol. - published September 8, 2016
2. Barrangou R, Doudna JA
Site-Specific Isotope-Labeling of Inosine Phosphoramidites and NMR Analysis of an Inosine-Containing RNA Duplex.
1. Chemistry - published September 8, 2016
2. Dallmann A, Beribisky AV, Gnerlich F, Rübbelke M, Schiesser S, Carell T, Sattler M
Evolution and Ecology of Actinobacteria and Their Bioenergy Applications.
1. Annu. Rev. Microbiol. - published September 8, 2016
2. Lewin GR, Carlos C, Chevrette MG, Horn HA, McDonald BR, Stankey RJ, Fox BG, Currie CR
Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires.
1. Cell - published September 8, 2016
2. Tian M, Cheng C, Chen X, Duan H, Cheng HL, Dao M, Sheng Z, Kimble M, Wang L, Lin S, Schmidt SD, Du Z, Joyce MG, Chen Y, DeKosky BJ, Chen Y, Normandin E, Cantor E, Chen RE, Doria-Rose NA, Zhang Y, Shi W, Kong WP, Choe M, Henry AR, Laboune F, Georgiev IS, Huang PY, Jain S, McGuire AT, Georgeson E, Menis S, Douek DC, Schief WR, Stamatatos L, Kwong PD, Shapiro L, Haynes BF, Mascola JR, Alt FW
Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.
1. Cell - published September 8, 2016
2. Robinson PJ, Trnka MJ, Bushnell DA, Davis RE, Mattei PJ, Burlingame AL, Kornberg RD
Teaching a Clone to Walk, One Step at a Time.
1. Cell - published September 8, 2016
2. Crowe JE Jr
Expression of C1ql3 in Discrete Neuronal Populations Controls Efferent Synapse Numbers and Diverse Behaviors.
1. Neuron - published September 7, 2016
2. Martinelli DC, Chew KS, Rohlmann A, Lum MY, Ressl S, Hattar S, Brunger AT, Missler M, Südhof TC
Characterization of VSV pseudotypes bearing essential entry glycoproteins gB, gD, gH, and gL of Herpes Simplex virus Type 1.
1. J. Virol. - published September 7, 2016
2. Rogalin HB, Heldwein EE
Next-generation electron microscopy in autophagy research.
1. Curr. Opin. Struct. Biol. - published September 7, 2016
2. Hurley JH, Nogales E
Tankyrase Sterile α Motif Domain Polymerization Is Required for Its Role in Wnt Signaling.
1. Structure - published September 6, 2016
2. Riccio AA, McCauley M, Langelier MF, Pascal JM
Structural Studies on KijD1, a Sugar C-3'-Methyltransferase.
1. Protein Sci. - published September 6, 2016
2. Dow GT, Thoden JB, Holden HM
A New Phase in ALS Research.
1. Structure - published September 6, 2016
2. Chong PA, Forman-Kay JD
Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1.
1. Proc. Natl. Acad. Sci. U.S.A. - published September 6, 2016
2. Gallego LD, Ghodgaonkar Steger M, Polyansky AA, Schubert T, Zagrovic B, Zheng N, Clausen T, Herzog F, Köhler A
A molecular arms race: new insights into anti-CRISPR mechanisms.
1. Nat Struct Mol Biol - published September 6, 2016
2. Mallon J, Bailey S
Protecting genome integrity during CRISPR immune adaptation.
1. Nat. Struct. Mol. Biol. - published September 5, 2016
2. Wright AV, Doudna JA
Delta chirality ruthenium 'light-switch' complexes can bind in the minor groove of DNA with five different binding modes.
1. Nucleic Acids Res. - published September 5, 2016
2. Hall JP, Keane PM, Beer H, Buchner K, Winter G, Sorensen TL, Cardin DJ, Brazier JA, Cardin CJ
PCNA tool belts and polymerase bridges form during translesion synthesis.
1. Nucleic Acids Res - published September 3, 2016
2. Boehm EM, Spies M, Washington MT
Structural insights into the IgE mediated responses induced by the allergens Hev b 8 and Zea m 12 in their dimeric forms.
1. Sci Rep - published September 3, 2016
2. Mares-Mejía I, Martínez-Caballero S, Garay-Canales C, Cano-Sánchez P, Torres-Larios A, Lara-González S, Ortega E, Rodríguez-Romero A
Developing EZH2-Targeted Therapy for Lung Cancer.
1. Cancer Discov - published September 3, 2016
2. Frankel AE, Liu X, Minna JD
Methods for Solving Highly Symmetric De Novo Designed Metalloproteins: Crystallographic Examination of a Novel Three-Stranded Coiled-Coil Structure Containing d-Amino Acids.
1. Meth. Enzymol. - published September 3, 2016
2. Ruckthong L, Stuckey JA, Pecoraro VL
High-resolution interrogation of functional elements in the noncoding genome.
1. Science - published September 3, 2016
2. Sanjana NE, Wright J, Zheng K, Shalem O, Fontanillas P, Joung J, Cheng C, Regev A, Zhang F
Opposing Functions of the N-terminal Acetyltransferases Naa50 and NatA in Sister-chromatid Cohesion.
1. J. Biol. Chem. - published September 2, 2016
2. Rong Z, Ouyang Z, Magin RS, Marmorstein R, Yu H
Molecular and Dynamic Mechanism Underlying Drug Resistance in Genotype 3 Hepatitis C NS3/4A Protease.
1. J. Am. Chem. Soc. - published September 2, 2016
2. Soumana DI, Kurt Yilmaz N, Ali A, Prachanronarong KL, Schiffer CA
Toward Precise Interpretation of DEER-Based Distance Distributions: Insights from Structural Characterization of V1 Spin-Labeled Side Chains.
1. Biochemistry - published September 2, 2016
2. Balo AR, Feyrer H, Ernst OP
Building Graphs To Describe Dynamics, Kinetics, and Energetics in the d-ALa:d-Lac Ligase VanA.
1. J Chem Inf Model - published September 2, 2016
2. Duclert-Savatier N, Bouvier G, Nilges M, Malliavin TE
Structural basis underlying viral hijacking of a histone chaperone complex.
1. Nat Commun - published September 2, 2016
2. Huang H, Deng Z, Vladimirova O, Wiedmer A, Lu F, Lieberman PM, Patel DJ
A microchip platform for structural oncology applications.
1. NPJ Breast Cancer - published September 2, 2016
2. Winton CE, Gilmore BL, Demmert AC, Karageorge V, Sheng Z, Kelly DF
Structure of Bor1 supports an elevator transport mechanism for SLC4 anion exchangers.
1. Proc Natl Acad Sci U S A - published September 2, 2016
2. Thurtle-Schmidt BH, Stroud RM
SIRT2 Reverses 4-Oxononanoyl Lysine Modification on Histones.
1. J Am Chem Soc - published September 2, 2016
2. Jin J, He B, Zhang X, Lin H, Wang Y
Role of dystroglycan in limiting contraction-induced injury to the sarcomeric cytoskeleton of mature skeletal muscle.
1. Proc Natl Acad Sci U S A - published September 2, 2016
2. Rader EP, Turk R, Willer T, Beltrán D, Inamori K, Peterson TA, Engle J, Prouty S, Matsumura K, Saito F, Anderson ME, Campbell KP
Science as a Way of Knowing: From Protein Machines to Evidence-Based Decisions.
1. Cell - published September 2, 2016
2. Walter P, Yamamoto KR
Bacterial flagellar capping proteins adopt diverse oligomeric states.
1. Elife - published September 2, 2016
2. Postel S, Deredge D, Bonsor DA, Yu X, Diederichs K, Helmsing S, Vromen A, Friedler A, Hust M, Egelman EH, Beckett D, Wintrode PL, Sundberg EJ
Topographic contrast of ultrathin cryo-sections for correlative super-resolution light and electron microscopy.
1. Sci Rep - published September 2, 2016
2. Mateos JM, Guhl B, Doehner J, Barmettler G, Kaech A, Ziegler U
Structural, antigenic and immunogenic features of respiratory syncytial virus glycoproteins relevant for vaccine development.
1. Vaccine - published September 2, 2016
2. Melero JA, Mas V, McLellan JS
Instantaneous ion configurations in the K+ ion channel selectivity filter revealed by 2D IR spectroscopy.
1. Science - published September 2, 2016
2. Kratochvil HT, Carr JK, Matulef K, Annen AW, Li H, Maj M, Ostmeyer J, Serrano AL, Raghuraman H, Moran SD, Skinner JL, Perozo E, Roux B, Valiyaveetil FI, Zanni MT
Coordinated Action of Nap1 and RSC in Disassembly of Tandem Nucleosomes.
1. Mol. Cell. Biol. - published September 1, 2016
2. Prasad R, D'Arcy S, Hada A, Luger K, Bartholomew B
Distinct Particle Morphologies Revealed through Comparative Parallel Analyses of Retrovirus-Like Particles.
1. J Virol - published September 1, 2016
2. Martin JL, Cao S, Maldonado JO, Zhang W, Mansky LM
Portability and Structure of the Four-Helix Bundle Docking Domains of trans-Acyltransferase Modular Polyketide Synthases.
1. ACS Chem Biol - published September 1, 2016
2. Zeng J, Wagner DT, Zhang Z, Moretto L, Addison JD, Keatinge-Clay AT
Purification and analysis of endogenous human RNA exosome complexes.
1. RNA - published September 1, 2016
2. Domanski M, Upla P, Rice WJ, Molloy KR, Ketaren NE, Stokes DL, Jensen TH, Rout MP, LaCava J
Author's reply.
1. Nat Rev Microbiol - published September 1, 2016
2. Tocheva EI, Ortega DR, Jensen GJ
Retargeted adenoviruses for radiation-guided gene delivery.
1. Cancer Gene Ther - published September 1, 2016
2. Kaliberov SA, Kaliberova LN, Yan H, Kapoor V, Hallahan DE
Cross-Correlated Relaxation of Dipolar Coupling and Chemical-Shift Anisotropy in Magic-Angle Spinning R1ρ NMR Measurements: Application to Protein Backbone Dynamics Measurements.
1. J Phys Chem B - published September 1, 2016
2. Kurauskas V, Weber E, Hessel A, Ayala I, Marion D, Schanda P
An ATP Binding Cassette Transporter Mediates the Uptake of α-(1,6)-Linked Dietary Oligosaccharides in Bifidobacterium and Correlates with Competitive Growth on These Substrates.
1. J Biol Chem - published September 1, 2016
2. Ejby M, Fredslund F, Andersen JM, Vujičić Žagar A, Henriksen JR, Andersen TL, Svensson B, Slotboom DJ, Abou Hachem M
Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids.
1. J Gen Physiol - published September 1, 2016
2. Lee SJ, Ren F, Zangerl-Plessl EM, Heyman S, Stary-Weinzinger A, Yuan P, Nichols CG
Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus.
1. Biochemistry - published September 1, 2016
2. Chang CY, Lohman JR, Cao H, Tan K, Rudolf JD, Ma M, Xu W, Bingman CA, Yennamalli RM, Bigelow L, Babnigg G, Yan X, Joachimiak A, Phillips GN, Shen B
Polyphosphate: A Conserved Modifier of Amyloidogenic Processes.
1. Mol. Cell - published September 1, 2016
2. Cremers CM, Knoefler D, Gates S, Martin N, Dahl JU, Lempart J, Xie L, Chapman MR, Galvan V, Southworth DR, Jakob U
A Catalytic Role for C-H/π Interactions in Base Excision Repair by Bacillus cereus DNA Glycosylase AlkD.
1. J. Am. Chem. Soc. - published September 1, 2016
2. Parsons ZD, Bland JM, Mullins EA, Eichman BF
Chemotaxis cluster 1 proteins form cytoplasmic arrays in Vibrio cholerae and are stabilized by a double signaling domain receptor DosM.
1. Proc Natl Acad Sci U S A - published September 1, 2016
2. Briegel A, Ortega DR, Mann P, Kjær A, Ringgaard S, Jensen GJ
How γ-secretase hits a moving target.
1. Elife - published September 1, 2016
2. Sanders CR
Synthesis of Aminoboronic Acid Derivatives from Amines and Amphoteric Boryl Carbonyl Compounds.
1. Angew. Chem. Int. Ed. Engl. - published September 1, 2016
2. Diaz DB, Scully CC, Liew SK, Adachi S, Trinchera P, St Denis JD, Yudin AK
DNA Targeting by a Minimal CRISPR RNA-Guided Cascade.
1. Mol. Cell - published September 1, 2016
2. Hochstrasser ML, Taylor DW, Kornfeld JE, Nogales E, Doudna JA
Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1.
1. Nucleic Acids Res. - published September 1, 2016
2. Hou C, Weidenbach S, Cano KE, Wang Z, Mitra P, Ivanov DN, Rohr J, Tsodikov OV
From deep TLS validation to ensembles of atomic models built from elemental motions. Addenda and corrigendum.
1. Acta Crystallogr D Struct Biol - published September 1, 2016
2. Urzhumtsev A, Afonine PV, Van Benschoten AH, Fraser JS, Adams PD
Cilia and Nuclear Pore Proteins: Pore No More?
1. Dev Cell - published September 1, 2016
2. Obado SO, Rout MP
Disruption of the Class IIa HDAC Corepressor Complex Increases Energy Expenditure and Lipid Oxidation.
1. Cell Rep - published September 1, 2016
2. Gaur V, Connor T, Sanigorski A, Martin SD, Bruce CR, Henstridge DC, Bond ST, McEwen KA, Kerr-Bayles L, Ashton TD, Fleming C, Wu M, Pike Winer LS, Chen D, Hudson GM, Schwabe JWR, Baar K, Febbraio MA, Gregorevic P, Pfeffer FM, Walder KR, Hargreaves M, McGee SL
Global Identification of Biofilm-Specific Proteolysis in Candida albicans.
1. mBio - published September 1, 2016
2. Winter MB, Salcedo EC, Lohse MB, Hartooni N, Gulati M, Sanchez H, Takagi J, Hube B, Andes DR, Johnson AD, Craik CS, Nobile CJ
Capture of associated targets on chromatin links long-distance chromatin looping to transcriptional coordination.
1. Nat Commun - published September 1, 2016
2. Bourgo RJ, Singhal H, Greene GL
Buried Hydrogen Bond Interactions Contribute to the High Potency of Complement Factor D Inhibitors.
1. ACS Med Chem Lett - published September 1, 2016
2. Yang CY, Phillips JG, Stuckey JA, Bai L, Sun H, Delproposto J, Brown WC, Chinnaswamy K
Discovery and Optimization of Two Eis Inhibitor Families as Kanamycin Adjuvants against Drug-Resistant <i>M. tuberculosis</i>.
1. ACS Med Chem Lett - published September 1, 2016
2. Garzan A, Willby MJ, Green KD, Tsodikov OV, Posey JE, Garneau-Tsodikova S
Balancing redox stress: anchorage-independent growth requires reductive carboxylation.
1. Transl Cancer Res - published September 1, 2016
2. Stalnecker CA, Cluntun AA, Cerione RA