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  • The SBGrid Consortium provides structural biologists worldwide with access to the software they need to discover the shapes of the molecules of life. Read more in eLIFE and Acta Cryst.

  • SBCloud: AWS platform optimized for structural biology; pre-configured with scientific software for cryoEM & other techniques; user-friendly Open OnDemand interface; seamless Slurm job submission.

  • Capsules isolate the software runtime environment, encapsulating executables, libraries, and version-specific dependencies to provide conflict-free, zero-configuration access to structural biology software. Learn more.

  • The Project MAC display system, circa 1965. Read more about the history of molecular graphics software and UCSF Chimera in our SBGrid Tale featuring Bob Langridge and Tom Ferrin.

  • Train the Trainer Workshops: continuing education for structural biology mentors on cryoEM data processing workflows; resources PIs can take back to the laboratory. Funded by NIH R25 GM151273.

  • Personal Installation Manager: a structural biology app store; users install preferred applications/ versions on laptops or personal workstations, with graphical or CLI interfaces for Mac or Linux. More details.

SBGrid Consortium homepage

Recent Software Updates

Software updates
Jul 31 | MemBrain-Seg

a tool for membrane segmentation in 3D for cryo-electron tomography (cryo-ET). >>

Jul 31 | pytom-match-pick

a GPU accelerated python module to significantly improve the speed and sensitivity using template matching to detect macromolecules from to… >>

Jul 31 | TomoDRGN

a tool that extends the cryoDRGN framework to cryo-ET by learning heterogeneity from datasets in which each particle is sampled by multiple… >>

Jul 31 | Doppio

a new web-based user interface for CCP-EM and RELION software. >>

Jul 30 | RDKit

a collection of cheminformatics and machine-learning software written in C++ and Python. >>

Jul 29 | Unicycler

an assembly pipeline for bacterial genomes. >>

Jul 28 | Boltz-1

an open-source model which predicts the 3D structure of proteins, rna, dna and small molecules; it handles modified residues, covalent liga… >>

Jul 23 | Volume_Seg_Tool

a tool that utilizes deep learning to perform volumetric electron microscopy image segmentations, both semantic and instance segmentation. >>

Jul 23 | cryoDRGN-AI

a neural network-based algorithm for ab initio heterogeneous cryo-EM reconstruction. >>

Jul 30 | autoPROC

a tool that combines third-party processing programs with new tools for automated data processing of single-sweep, multi-sweep and multi-cr… >>

Thanks to the National Science Foundation

With partial support from the NIH R25 Continuing Education for Structural Biology Mentors #GM151273, in collaboration with Co-PI Jamaine Davis; the NSF Research Coordination Network MCB #0639193, and NSF EAGER #1448069. Please cite SBGrid's eLife paper and follow our publication guidelines.

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Latest upgrades from SBGrid, including latest software updates, new members and special events. Published montly by SBGrid.

SBGrid Webinar Series

Join us for our Software Webinar Series - Tuesdays at 12pm ET - to hear from software developers about what's new in structural biology. Community members connect via Zoom. Subscribe …

SBGrid/Harvard Shield

Capsules Technology

We have recently published a manuscript describing our Capsules technology used to deploy SBGrid and BioGrids software collections. Read more in Acta Cryst Section D, special 75th ICUR anniversary issue, …

Connecting SBGrid with Instruct-ERIC

SBGrid is pleased to announce that it has established a partnership with Instruct-ERIC, based in Oxford, UK. Instruct-ERIC is a pan-European distributed research infrastructure with a hub in Oxford, UK …

The Final Phase

The Final Phase

For a person intent on tiny forms, George Phillips's career has been closely tied to big initiatives that have added new categories of structures to the Protein Data Bank. He …

Member publications

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