Supported Applications

Topaz

Description

a pipeline for particle detection in cryo-electron microscopy images using convolutional neural networks trained from positive and unlabeled examples. Topaz includes methods for micrograph denoising using deep denoising models.
Usage
To list all executables provided by Topaz, run: $ sbgrid-list topaz
Installation
Use the following command to install this title with the CLI client: $ sbgrid-cli install topaz Available operating systems: Linux 64
Primary Citation*

T. Bepler, A. Morin, M. Rapp, J. Brasch, L. Shapiro, and A. J. N. &. B. Berger. 2019. Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs. Nature Methods. 16: 1153-1160.
- *Full citation information available through
Webinars

Topic: Topaz: particle picking with positive-unlabeled learning
Speaker: Tristan Bepler, MIT

Host: Jason Key
Recorded on Feb 26, 2019