Supported Applications


  • Description

    (Python-based Hierarchical Environment for INtegrated Xtallography) a software suite for the automated determination of molecular structures using X-ray crystallography and other methods.

  • Usage Notes

    If you use PHENIX to solve a structure please cite this publication:

    PHENIX: building new software for automated crystallographic structure determination P.D. Adams, R.W. Grosse-Kunstleve, L.-W. Hung, T.R. Ioerger, A.J. McCoy, N.W. Moriarty, R.J. Read, J.C. Sacchettini, N.K. Sauter and T.C. Terwilliger. Acta Cryst. D58, 1948-1954 (2002)

  • Primary Citation*

    P. D. Adams, P. V. Afonine, G. Bunkóczi, V. B. Chen, I. W. Davis, N. Echols, J. J. Headd, L.-W. Hung, G. J. Kapral, R. W. Grosse-Kunstleve, A. J. McCoy, N. W. Moriarty, R. Oeffner, R. J. Read, D. C. Richardson, J. S. Richardson, T. C. Terwilliger, and P. H. Zwart. 2010. PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta crystallographica Section D: Biological crystallography. 66(2): 213-221.

    • *Full citation information available through

    Citation Note

    Citations for all software packages used in a given project can also be generated from within PHENIX.

  • Categories

    Crystallography, Structural Biology

  • Default Versions

    Linux 64 1.11.1-2575
    OS X INTEL 1.11.1-2575

  • Other Available Versions

    Linux 32 1.8.2-1309
    Linux 32 1.8.3-1479
    Linux 32 1.8.4-1496
    Linux 32 dev-1565
    Linux 64 1.10-2155
    Linux 64 dev-2645
    Linux 64 nightly
    OS X INTEL 1.10-2155
    OS X INTEL dev-2645
    OS X INTEL nightly
    powermac 1.7-650
    powermac dev-739

  • Developers

    Paul Adams, Pavel Afonine, Nat Echols.

  • Tales

    Structures Solved Simply

    Structures Solved Simply

    It used to be that to book a trip you'd first need to call every airline to compare flights. Then you'd need to find good hotel deals. Then you'd have to revisit the flights. And so on. The same trial and error approach also used to hold true for structural biology. Frequent failures made scientists all too familiar with square one.

    Now, however, what Orbitz and Expedia have done for travel, Phenix has done for structural biology.

    Phenix helps investigators solve Xray crystal structures using multiple approaches, including molecular replacement and experimental phasing. It makes things easier by streamlining these multi-step procedures programmatically. Experimental data goes in, and a solution comes out.

    Phenix Wizards perform the magic. For instance, the autosol program drives experimental phasing ...

    Read More.