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  • Description

    a software package for single-particle EM image processing. It provides an integrated computing environment with comprehensive data analysis functions for particle selection, particle classification, 3D reconstruction and model evaluation. In addition, PARTICLE emphasizes on data visualization that enables the user to "see" the data throughout the process.

  • Usage

    To list all executables provided by PARTICLE, run: $ sbgrid-list particle Copy to clipboard
  • Usage Notes

    Chen, Z et al (2012). PARTICLE (Version 1.0) [Software]. Available from

  • Installation

    Use the following command to install this title with the CLI client: $ sbgrid-cli install particle Copy to clipboard Available operating systems: Linux 64, OS X INTEL
  • Citation Note

    If you are using PARTICLE, please cite the manual at
  • Tales

    New Kid on the Block

    New Kid on the Block

    James Chen was raised by mathematicians who taught him at an early age to program computers and to think analytically. “Everything had to be formulated. Instead of speaking in natural language, we sometimes spoke in formulae at home,” Chen says with a laugh. No surprise, then, that Chen, assistant professor of biochemistry and molecular biology at the Oregon Health and Science University (OHSU), became an expert in electron microscopy data analysis.

    Physics appealed to him as a college student in China, but as a graduate student at Florida State University, he found himself lured into biophysics. He began working with Michael Chapman, now also at OHSU, on an X-ray crystallography project to perform structure refinement in real space — against the electron density map — rather than in …

    Read the full story here.
  • Webinars


    Topic: PARTICLE: an Integrated Computing Platform for Single-Particle Electron Microscopy
    Presenter: James Chen, Ph.D., Research Scientist, Dept of Biology, MIT

    Host: Piotr Sliz
    Recorded on October 4, 2012

  • Keywords

    Electron Microscopy

  • Default Versions

    Linux 64:  1.0 (11.4 MB)
    OS X INTEL:  1.0 (7.8 MB)

  • Developers

    James Chen