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Supported Applications


  • Description

    a tool to predict protein structure, function, and mutations using evolutionary sequence covariation.

  • Usage

    To list all executables provided by EVcouplings, run: $ sbgrid-list evcouplings Copy to clipboard
  • Installation

    Use the following command to install this title with the CLI client: $ sbgrid-cli install evcouplings Copy to clipboard Available operating systems: Linux 64, OS X INTEL
  • Primary Citation*

    D. S. Marks, L. J. Colwell, R. Sheridan, T. A. Hopf, A. Pagnani, R. Zecchina, and C. Sander. 2011. Protein 3D Structure Computed from Evolutionary Sequence Variation. PLOS ONE. 6(12): e28766.

    • *Full citation information available through

  • Webinars


    Topic: EVcouplings: Using evolution to determine structure and function
    Presenters: Kelly Brock, Ph.D., Laboratory of Debora Marks, Harvard Medical School and Thomas Hopf, Ph.D., Scientific Consultant

    Host: Pete Meyer
    Recorded on May 12, 2020

  • Keywords

    Protein Structure Analysis

  • Default Versions

    Linux 64:  0.1.1 (3.2 GB)
    OS X INTEL:  0.1.1 (3.7 GB)

  • Other Versions

      Linux 64:

      0.0.1 (827.5 MB) , 0.0.5 (2.4 GB)
    • OS X INTEL:

      0.0.1 (355.2 MB)
  • Developers

    Chris Sander, Debora S Marks, Thomas Hopf