Supported Applications
EMBuild
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Description
an automatic model building method of multi-chain protein complexes from intermediate-resolution cryo-EM maps, integrating AlphaFold structure prediction, FFT-based global fitting, domain-based semi-flexible refinement, and graph-based iterative assembling on the main-chain probability map predicted by a deep convolutional network.
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Usage
To list all executables provided by EMBuild, run:$ sbgrid-list embuild
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Usage Notes
EMBuild requires the STRIDE program. Users must download this before using EMBuild.
http://webclu.bio.wzw.tum.de/stride/stride.tar.gz
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Installation
Use the following command to install this title with the CLI client:$ sbgrid-cli install embuild
Available operating systems: Linux 64 -
Primary Citation*
J. He, P. Lin, J. Chen, H. Cao, and S. Y. Huang. 2022. Model building of protein complexes from intermediate-resolution cryo-EM maps with deep learning-guided automatic assembly. Nature communications. 13(1): 4066.
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*Full citation information available through
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Keywords
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Default Versions
Linux 64:  1.0 (5.2 GB)
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Developers
Sheng-You Huang, Peicong Lin, Jiahua He, Ji Chen, Hong Cao