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  • Description

    an automatic model building method of multi-chain protein complexes from intermediate-resolution cryo-EM maps, integrating AlphaFold structure prediction, FFT-based global fitting, domain-based semi-flexible refinement, and graph-based iterative assembling on the main-chain probability map predicted by a deep convolutional network.

  • Usage

    To list all executables provided by EMBuild, run: $ sbgrid-list embuild Copy to clipboard
  • Usage Notes

    EMBuild requires the STRIDE program. Users must download this before using EMBuild.

  • Installation

    Use the following command to install this title with the CLI client: $ sbgrid-cli install embuild Copy to clipboard Available operating systems: Linux 64
  • Primary Citation*

    J. He, P. Lin, J. Chen, H. Cao, and S. Y. Huang. 2022. Model building of protein complexes from intermediate-resolution cryo-EM maps with deep learning-guided automatic assembly. Nature communications. 13(1): 4066.

    • *Full citation information available through

  • Keywords


  • Default Versions

    Linux 64:  1.0 (5.2 GB)

  • Developers

    Sheng-You Huang, Peicong Lin, Jiahua He, Ji Chen, Hong Cao