For SBGrid users who are already familiar with the SBGrid software installation platform, members may opt-in in to include the BioGrids software stack in their installation. BioGrids in an SBGrid-style collection of ~ 500 open source bioinformatics software titles, with collections for high-throughput sequencing, genomics, proteomics, visualization, image analysis, etc.
Our resident bioinformatics expert, Jim Vincent, recorded this brief tutorial - BioGrids for SBGrid Users - with more information on how SBGrid users can access this software stack. Contact us at help@biogrids.org with any questions.
Many thanks to all who joined our most recent mini-series - Cryo-electron microscopy: from Sample to Structure - hosted in collaboration with Prof. Kurt Krause of University of Otago, Prof. Piotr Sliz of Harvard Medical School, and Prof. Antoine van Oijen, University of Wollongong and ARC CCeMMP.
The samples preparation, cryoEM computing, and regional infrastructure talks are available on SBGridTV.
We are looking forward to preparing another webinar series in 2022 - stay tuned!
Join us for our Software Webinar Series - Tuesdays at 12pm ET - to hear from software developers about what's new in structural biology.
Community members connect via Zoom.
Subscribe to SBGridTV to receive new video alerts and view our collection of past tutorials.
Events are posted on the SBGrid public calendar: https://sbgrid.org/calendar/.
Registration information coming soon.
We've got a couple of operating system alerts for those of you looking to buy new computers or update existing Mac or Linux machines:
SBGrid is not compatible with MacOS 10.15 "Catalina without a work-around for recent filesystem changes", the next version of Apple's MacOS due out in October with significant changes. With Catalina, Apple will enforce strict filesystem controls that will break SBGrid installations. They have also dropped support for 32-bit binaries that many older applications require. We strongly recommend against upgrading to 10.15 on any Mac with SBGrid software. A solution is in the works, but it may take some time before we can fully implement the changes to officially support 10.15. We are also compiling a list of 32-bit software applications that will …
The evolution of SBGrid tracks with advances in structural biology, and cryo-EM is at the forefront of that change. This article reflects on 3 pivotal papers that describe key advances in cryoEM, from member laboratories and software contributors who were early participants in SBGrid. Read the full story.
Image caption: A clathrin cage with a single triskelion highlighted in blue. CryoEM map EMD_5119 was rendered in UCSF Chimera and one clathrin triskelion was highlighted. Image courtesy of Mazuraan CC BY-SA 4.0 license.