Published: July 31, 2019
The evolution of SBGrid tracks with advances in structural biology, and cryo-EM is at the forefront of that change. This article reflects on 3 pivotal papers that describe key advances in cryoEM, from …
News
Published: July 30, 2019
When Marcos Sotomayor explains his research out loud, his voice tickles the topic of his studies. A core biological question in his laboratory addresses how hearing happens at the molecular level. For words …
Updated: June 28, 2019
Hao Wu is a third generation scientist whose formative years were shaped by the Chinese Cultural Revolution. In fact, it’s fair to say the revolution, better known for persecution of academics and intellectuals, …
Updated: June 27, 2019
With the 2017 Nobel Prize, cryo-electron microscopy became briefly famous outside of the growing clutch of scientists using the techniques to capture detailed views of molecules that keep life humming along. The prize …
Updated: June 21, 2019
The Natural Bridge In 2013, Piotr Sliz and the team at SBGrid published a paper in eLife describing, for the first time in a formal, academic fashion, the SBGrid model. In existence since …
Updated: May 29, 2019
The applications listed below are freely available to non-profit labs, but each lab must register individually before we can install the software. If you would like any of these titles included in your …
Updated: May 28, 2019
As an undergraduate at University of Montpellier in France in the early 2000s, Sébastien Granier’s interest in science was stoked by the passionate lectures of a renowned plant physiologist who studied the architecture …
Updated: May 28, 2019
When Alejandro Buschiazzo took on the responsibility of building a structural biology core facility in Latin America, he was taking a risk. He was an assistant professor at the Institut Pasteur in Paris, …
Updated: May 28, 2019
After earning a chemistry degree at MIT in 1985, Julie Forman-Kay headed to Yale for graduate work in the lab of structural biology pioneer Fred Richards. Forman-Kay – who says she never grew …
Updated: May 28, 2019
Watch SBGridTV on YouTube. If you missed any of the webinars from our SBGrid Lunch Break series, featuring software developers introducing new releases, suggesting helpful tips and tricks, or offering a basic tutorial …
Updated: May 28, 2019
When Pawel Penczek took his first job in the lab of Joachim Frank, a pioneer in cryo-Electron Microscopy, he had never heard about the technique. "My interest was in digital signal processing," says …
Published: April 29, 2019
First, let’s clear the air about one thing: HADDOCK, a popular tool to model interactions between biomolecules, is not named after a saltwater cod. “It’s not about the fish,” says Alexandre M. J. …
Updated: March 28, 2019
Genetic damage can set the stage for normal cells to turn into cancer. So it may be surprising that blocking a DNA damage repair molecule can kill some cancer cells. John Pascal became …
Updated: March 22, 2019
It used to be that to book a trip you'd first need to call every airline to compare flights. Then you'd need to find good hotel deals. Then you'd have to revisit the …
Updated: Feb. 1, 2019
Rejection is an unavoidable part of science, whether it’s funding for research or manuscripts submitted for publication. But few people showcase their setbacks like Nikolaus “Niko” Grigorieff, whose lab web site features a …
Updated: Dec. 19, 2018
For Bil Clemons, the first glimpse of a protein structure never gets old. “Seeing the electron density for the first time—it’s still just magical and one of the greatest experiences you can have …
Updated: Nov. 29, 2018
One day, a recently retired colleague visited S. Ramaswamy in his University of Iowa laboratory and presented him with a fish from a Canadian lake and a question. Why was the fish blue? …
Updated: Oct. 29, 2018
But for the luck of a graduate school admission lottery, Sjors Scheres might have followed in his dad’s steps and become a veterinarian. Instead, he headed in a different direction, creating a new …
Published: Sept. 27, 2018
As a physics undergraduate student in Munich, Gerhard Wagner worked on an esoteric atomic measurement of iron in a protein molecule. Then he heard from his supervisor, who was on sabbatical at Bell …
Updated: Aug. 3, 2018
Evidence of the Higgs boson appears as a bump on a histogram resulting from the analysis of data from millions of detectors at the Large Hadron Collider. What if all that raw data …