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150 Member Publications for March

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Mapping the functional landscape of the receptor binding domain of T7 bacteriophage by deep mutational scanning.
1. Elife - published March 9, 2021
2. Huss P, Meger A, Leander M, Nishikawa KK, Raman S
Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody.
1. Proc Natl Acad Sci U S A - published March 9, 2021
2. Madan B, Zhang B, Xu K, Chao CW, O'Dell S, Wolfe JR, Chuang GY, Fahad AS, Geng H, Kong R, Louder MK, Nguyen TD, Rawi R, Schön A, Sheng Z, Nimrania R, Wang Y, Zhou T, Lin BC, Doria-Rose NA, Shapiro L, Kwong PD, DeKosky BJ
Polarization Effects in Water-Mediated Selective Cation Transport across a Narrow Transmembrane Channel.
1. J Chem Theory Comput - published March 9, 2021
2. Ngo V, Li H, MacKerell AD Jr, Allen TW, Roux B, Noskov S
Computational studies of anaplastic lymphoma kinase mutations reveal common mechanisms of oncogenic activation.
1. Proc Natl Acad Sci U S A - published March 9, 2021
2. Patil K, Jordan EJ, Park JH, Suresh K, Smith CM, Lemmon AA, Mossé YP, Lemmon MA, Radhakrishnan R
Single-Shot Vaccines against Bovine Respiratory Syncytial Virus (BRSV): Comparative Evaluation of Long-Term Protection after Immunization in the Presence of BRSV-Specific Maternal Antibodies.
1. Vaccines (Basel) - published March 9, 2021
2. Valarcher JF, Hägglund S, Näslund K, Jouneau L, Malmström E, Boulesteix O, Pinard A, Leguéré D, Deslis A, Gauthier D, Dubuquoy C, Pietralunga V, Rémot A, Falk A, Shevchenko G, Bergström Lind S, Von Brömssen C, Vargmar K, Zhang B, Kwong PD, Rodriguez MJ, Garcia Duran M, Schwartz-Cornil I, Taylor G, Riffault S
Structural basis for IFN antagonism by human respiratory syncytial virus nonstructural protein 2.
1. Proc Natl Acad Sci U S A - published March 9, 2021
2. Pei J, Wagner ND, Zou AJ, Chatterjee S, Borek D, Cole AR, Kim PJ, Basler CF, Otwinowski Z, Gross ML, Amarasinghe GK, Leung DW
Maternal Iron Deficiency Modulates Placental Transcriptome and Proteome in Mid-Gestation of Mouse Pregnancy.
1. J Nutr - published March 9, 2021
2. Cao C, Prado MA, Sun L, Rockowitz S, Sliz P, Paulo JA, Finley D, Fleming MD
Pleiotropic consequences of metabolic stress for the major histocompatibility complex class II molecule antigen processing and presentation machinery.
1. Immunity - published March 9, 2021
2. Clement CC, Nanaware PP, Yamazaki T, Negroni MP, Ramesh K, Morozova K, Thangaswamy S, Graves A, Kim HJ, Li TW, Vigano' M, Soni RK, Gadina M, Tse HY, Galluzzi L, Roche PA, Denzin LK, Stern LJ, Santambrogio L
Full methylation of H3K27 by PRC2 is dispensable for initial embryoid body formation but required to maintain differentiated cell identity.
1. Development - published March 9, 2021
2. Miller SA, Damle M, Kim J, Kingston RE
Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery.
1. Immunity - published March 9, 2021
2. Chiou SH, Tseng D, Reuben A, Mallajosyula V, Molina IS, Conley S, Wilhelmy J, McSween AM, Yang X, Nishimiya D, Sinha R, Nabet BY, Wang C, Shrager JB, Berry MF, Backhus L, Lui NS, Wakelee HA, Neal JW, Padda SK, Berry GJ, Delaidelli A, Sorensen PH, Sotillo E, Tran P, Benson JA, Richards R, Labanieh L, Klysz DD, Louis DM, Feldman SA, Diehn M, Weissman IL, Zhang J, Wistuba II, Futreal PA, Heymach JV, Garcia KC, Mackall CL, Davis MM
Itaconate confers tolerance to late NLRP3 inflammasome activation.
1. Cell Rep - published March 9, 2021
2. Bambouskova M, Potuckova L, Paulenda T, Kerndl M, Mogilenko DA, Lizotte K, Swain A, Hayes S, Sheldon RD, Kim H, Kapadnis U, Ellis AE, Isaguirre C, Burdess S, Laha A, Amarasinghe GK, Chubukov V, Roddy TP, Diamond MS, Jones RG, Simons DM, Artyomov MN
Conformational dynamics in interleukin 17A and 17F functional complexes is a key determinant of receptor A affinity and specificity.
1. Cytokine - published March 8, 2021
2. Waters LC, Veverka V, Strong SL, Muskett FW, Dedi N, Lawson ADG, Prosser CE, Taylor RJ, Henry AJ, Carr MD
Cryo-EM structures of human coagulation factors V and Va.
1. Blood - published March 8, 2021
2. Ruben EA, Rau MJ, Fitzpatrick J, Di Cera E
Efficient and flexible synthesis of new photoactivatable propofol analogs.
1. Bioorg Med Chem Lett - published March 8, 2021
2. Skinner KA, Wzorek JS, Kahne D, Gaudet R
NMR and EPR reveal a compaction of the RNA-binding protein FUS upon droplet formation.
1. Nat Chem Biol - published March 8, 2021
2. Emmanouilidis L, Esteban-Hofer L, Damberger FF, de Vries T, Nguyen CKX, Ibáñez LF, Mergenthal S, Klotzsch E, Yulikov M, Jeschke G, Allain FH
Structure of the FA core ubiquitin ligase closing the ID clamp on DNA.
1. Nat Struct Mol Biol - published March 8, 2021
2. Wang S, Wang R, Peralta C, Yaseen A, Pavletich NP
Engineering of Challenging G Protein-Coupled Receptors for Structure Determination and Biophysical Studies.
1. Molecules - published March 8, 2021
2. Waltenspühl Y, Ehrenmann J, Klenk C, Plückthun A
Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7.
1. Nature - published March 8, 2021
2. Wang P, Nair MS, Liu L, Iketani S, Luo Y, Guo Y, Wang M, Yu J, Zhang B, Kwong PD, Graham BS, Mascola JR, Chang JY, Yin MT, Sobieszczyk M, Kyratsous CA, Shapiro L, Sheng Z, Huang Y, Ho DD
Oligomeric complexes formed by Redβ single strand annealing protein in its different DNA bound states.
1. Nucleic Acids Res - published March 8, 2021
2. Caldwell BJ, Norris A, Zakharova E, Smith CE, Wheat CT, Choudhary D, Sotomayor M, Wysocki VH, Bell CE
Structural basis of the human Scribble-Vangl2 association in health and disease.
1. Biochem J - published March 8, 2021
2. How JY, Stephens R, Lim KYB, Humbert PO, Kvansakul M
Pirtobrutinib in relapsed or refractory B-cell malignancies (BRUIN): a phase 1/2 study.
1. Lancet - published March 6, 2021
2. Mato AR, Shah NN, Jurczak W, Cheah CY, Pagel JM, Woyach JA, Fakhri B, Eyre TA, Lamanna N, Patel MR, Alencar A, Lech-Maranda E, Wierda WG, Coombs CC, Gerson JN, Ghia P, Le Gouill S, Lewis DJ, Sundaram S, Cohen JB, Flinn IW, Tam CS, Barve MA, Kuss B, Taylor J, Abdel-Wahab O, Schuster SJ, Palomba ML, Lewis KL, Roeker LE, Davids MS, Tan XN, Fenske TS, Wallin J, Tsai DE, Ku NC, Zhu E, Chen J, Yin M, Nair B, Ebata K, Marella N, Brown JR, Wang M
In vitro and in vivo inhibition of malaria parasite infection by monoclonal antibodies against Plasmodium falciparum circumsporozoite protein (CSP).
1. Sci Rep - published March 5, 2021
2. Livingstone MC, Bitzer AA, Giri A, Luo K, Sankhala RS, Choe M, Zou X, Dennison SM, Li Y, Washington W, Ngauy V, Tomaras GD, Joyce MG, Batchelor AH, Dutta S
A "Drug Sweeping" State of the TriABC Triclosan Efflux Pump from Pseudomonas aeruginosa.
1. Structure - published March 4, 2021
2. Fabre L, Ntreh AT, Yazidi A, Leus IV, Weeks JW, Bhattacharyya S, Ruickoldt J, Rouiller I, Zgurskaya HI, Sygusch J
Defective lysosomal storage in Fabry Disease modifies mitochondrial structure, metabolism and turnover in renal epithelial cells.
1. J Inherit Metab Dis - published March 4, 2021
2. Schumann A, Schaller K, Belche V, Cybulla M, Grünert SC, Moers N, Sass JO, Kaech A, Hannibal L, Spiekerkoetter U
Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers.
1. PLoS One - published March 4, 2021
2. Cohen AA, Yang Z, Gnanapragasam PNP, Ou S, Dam KA, Wang H, Bjorkman PJ
Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies.
1. Nat Med - published March 4, 2021
2. Chen RE, Zhang X, Case JB, Winkler ES, Liu Y, VanBlargan LA, Liu J, Errico JM, Xie X, Suryadevara N, Gilchuk P, Zost SJ, Tahan S, Droit L, Turner JS, Kim W, Schmitz AJ, Thapa M, Wang D, Boon ACM, Presti RM, O'Halloran JA, Kim AHJ, Deepak P, Pinto D, Fremont DH, Crowe JE Jr, Corti D, Virgin HW, Ellebedy AH, Shi PY, Diamond MS
Integrated genomic analysis reveals regulatory pathways and dynamic landscapes of the tRNA transcriptome.
1. Sci Rep - published March 4, 2021
2. Sun Z, Tan J, Zhao M, Peng Q, Zhou M, Zuo S, Wu F, Li X, Dong Y, Xie M, Yang Y, Zhou J, Liu X, He Q, He Z, Yu X, He Q
N-terminal transmembrane-helix epitope tag for x-ray crystallography and electron microscopy of small membrane proteins.
1. J Mol Biol - published March 4, 2021
2. McIlwain BC, Erwin AL, Davis AR, Ben Koff B, Chang L, Bylund T, Chuang GY, Kwong PD, Ohi MD, Lai YT, Stockbridge RB
Intestinal host response to SARS-CoV-2 infection and COVID-19 outcomes in patients with gastrointestinal symptoms.
1. Gastroenterology - published March 3, 2021
2. Livanos AE, Jha D, Cossarini F, Gonzalez-Reiche AS, Tokuyama M, Aydillo T, Parigi TL, Ladinsky MS, Ramos I, Dunleavy K, Lee B, Dixon R, Chen ST, Martinez-Delgado G, Nagula S, Bruce EA, Ko HM, Glicksberg BS, Nadkarni G, Pujadas E, Reidy J, Naymagon S, Grinspan A, Ahmad J, Tankelevich M, Bram Y, Gordon R, Sharma K, Houldsworth J, Britton GJ, Chen-Liaw A, Spindler MP, Plitt T, Wang P, Cerutti A, Faith JJ, Colombel JF, Kenigsberg E, Argmann C, Merad M, Gnjatic S, Harpaz N, Danese S, Cordon-Cardo C, Rahman A, Schwartz RE, Kumta NA, Aghemo A, Bjorkman PJ, Petralia F, van Bakel H, Garcia-Sastre A, Mehandru S
Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates.
1. Sci Transl Med - published March 3, 2021
2. Darricarrère N, Qiu Y, Kanekiyo M, Creanga A, Gillespie RA, Moin SM, Saleh J, Sancho J, Chou TH, Zhou Y, Zhang R, Dai S, Moody A, Saunders KO, Crank MC, Mascola JR, Graham BS, Wei CJ, Nabel GJ
Dual role of endothelial Myct1 in tumor angiogenesis and tumor immunity.
1. Sci Transl Med - published March 3, 2021
2. Kabir AU, Subramanian M, Lee DH, Wang X, Krchma K, Wu J, Naismith T, Halabi CM, Kim JY, Pulous FE, Petrich BG, Kim S, Park HC, Hanson PI, Pan H, Wickline SA, Fremont DH, Park C, Choi K
Structural insights into the inhibition of glycine reuptake.
1. Nature - published March 3, 2021
2. Shahsavar A, Stohler P, Bourenkov G, Zimmermann I, Siegrist M, Guba W, Pinard E, Sinning S, Seeger MA, Schneider TR, Dawson RJP, Nissen P
Allogeneic transplantation after PD-1 blockade for classic Hodgkin lymphoma.
1. Leukemia - published March 3, 2021
2. Merryman RW, Castagna L, Giordano L, Ho VT, Corradini P, Guidetti A, Casadei B, Bond DA, Jaglowski S, Spinner MA, Arai S, Lowsky R, Shah GL, Perales MA, De Colella JMS, Blaise D, Herrera AF, Shouse G, Spilleboudt C, Ansell SM, Nieto Y, Badar T, Hamadani M, Feldman TA, Dahncke L, Singh AK, McGuirk JP, Nishihori T, Chavez J, Serritella AV, Kline J, Mohty M, Dulery R, Stamatoulas A, Houot R, Manson G, Moles-Moreau MP, Orvain C, Bouabdallah K, Modi D, Ramchandren R, Lekakis L, Beitinjaneh A, Frigault MJ, Chen YB, Lynch RC, Smith SD, Rao U, Byrne M, Romancik JT, Cohen JB, Nathan S, Phillips T, Joyce RM, Rahimian M, Bashey A, Ballard HJ, Svoboda J, Torri V, Sollini M, De Philippis C, Magagnoli M, Santoro A, Armand P, Zinzani PL, Carlo-Stella C
An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation.
1. Prog Biophys Mol Biol - published March 3, 2021
2. Nguyen MT, Moiani D, Ahmed Z, Arvai AS, Namjoshi S, Shin DS, Fedorov Y, Selvik EJ, Jones DE, Pink J, Yan Y, Laverty DJ, Nagel ZD, Tainer JA, Gerson SL
DeepAlign, a 3D Alignment Method based on Regionalized Deep Learning for Cryo-EM.
1. J Struct Biol - published March 3, 2021
2. Jiménez-Moreno A, Střelák D, Filipovič J, Carazo JM, Sorzano COS
Cryo-EM structure of the yeast TREX complex and coordination with the SR-like protein Gbp2.
1. Elife - published March 3, 2021
2. Xie Y, Clarke BP, Kim YJ, Ivey AL, Hill PS, Shi Y, Ren Y
Intrapleural Fibrinolytics and Deoxyribonuclease for Treatment of Indwelling Pleural Catheter-Related Pleural Infection: A Multi-Center Observational Study.
1. Respiration - published March 3, 2021
2. Fitzgerald DB, Muruganandan S, Tsim S, Ip H, Asciak R, Walker S, Uribe Becerra JP, Majid A, Ahmed L, Rahman NM, Maskell NA, Blyth KG, Lee YCG
Crystal structures of influenza nucleoprotein complexed with nucleic acid provide insights into the mechanism of RNA interaction.
1. Nucleic Acids Res - published March 3, 2021
2. Tang YS, Xu S, Chen YW, Wang JH, Shaw PC
Structural Mechanisms for Replicating DNA in Eukaryotes.
1. Annu Rev Biochem - published March 3, 2021
2. Attali I, Botchan MR, Berger JM
Crystal structure of an inulosucrase from Halalkalicoccus jeotgali B3T-a halophilic archaeal strain.
1. FEBS J - published March 3, 2021
2. Ghauri K, Pijning T, Munawar N, Ali H, Ghauri MA, Anwar MA, Wallis R
Thymosin β4 protects against aortic aneurysm via endocytic regulation of growth factor signaling.
1. J Clin Invest - published March 3, 2021
2. Munshaw S, Bruche S, Redpath AN, Jones A, Patel J, Dubé KN, Lee R, Hester SS, Davies R, Neal G, Handa A, Sattler M, Fischer R, Channon KM, Smart N
Arf1 orchestrates Rab GTPase conversion at the trans-Golgi network.
1. Mol Biol Cell - published March 3, 2021
2. Thomas LL, Highland CM, Fromme JC
Peripheral Methionine Residues Impact Flavin Photoreduction and Protonation in an Engineered LOV Domain Light Sensor.
1. Biochemistry - published March 3, 2021
2. Yee EF, Oldemeyer S, Böhm E, Ganguly A, York DM, Kottke T, Crane BR
Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons.
1. Cell Rep - published March 3, 2021
2. Ipsaro JJ, O'Brien PA, Bhattacharya S, Palmer AG 3rd, Joshua-Tor L
Arf1 directly recruits the Pik1-Frq1 PI4K complex to regulate the final stages of Golgi maturation.
1. Mol Biol Cell - published March 3, 2021
2. Highland CM, Fromme JC
A positively charged surface patch on the pestivirus NS3 protease module plays an important role in modulating NS3 helicase activity and virus production.
1. Arch Virol - published March 3, 2021
2. Zheng F, Yi W, Liu W, Zhu H, Gong P, Pan Z
Dysfunction of the proteoglycan Tsukushi causes hydrocephalus through altered neurogenesis in the subventricular zone in mice.
1. Sci Transl Med - published March 3, 2021
2. Ito N, Riyadh MA, Ahmad SAI, Hattori S, Kanemura Y, Kiyonari H, Abe T, Furuta Y, Shinmyo Y, Kaneko N, Hirota Y, Lupo G, Hatakeyama J, Abdulhaleem M FA, Anam MB, Yamaguchi M, Takeo T, Takebayashi H, Takebayashi M, Oike Y, Nakagata N, Shimamura K, Holtzman MJ, Takahashi Y, Guillemot F, Miyakawa T, Sawamoto K, Ohta K
Structural basis of malaria RIFIN binding by LILRB1-containing antibodies.
1. Nature - published March 3, 2021
2. Chen Y, Xu K, Piccoli L, Foglierini M, Tan J, Jin W, Gorman J, Tsybovsky Y, Zhang B, Traore B, Silacci-Fregni C, Daubenberger C, Crompton PD, Geiger R, Sallusto F, Kwong PD, Lanzavecchia A
The renaissance in biophysics and molecular biology enabled by the interface of DNA repair and replication with cancer.
1. Prog Biophys Mol Biol - published March 3, 2021
2. Zhang X, Blundell T, Tainer JA
Hsp70 chaperone blocks α-synuclein oligomer formation via a novel engagement mechanism.
1. J Biol Chem - published March 3, 2021
2. Tao J, Berthet A, Citron YR, Tsiolaki PL, Stanley R, Gestwicki JE, Agard DA, McConlogue L
Effectiveness of mechanical cardiopulmonary resuscitation for patients with COVID-19 and in hospital cardiac arrest.
1. Resuscitation - published March 3, 2021
2. Bhardwaj A, Alwakeel M, Wang X, Duggal A, Gaieski DF, Fadel FA
Structural basis for the initiation of COPII vesicle biogenesis.
1. Structure - published March 3, 2021
2. Joiner AMN, Fromme JC
Distinct intramolecular interactions regulate autoinhibition of vinculin binding in αT-catenin and αE-catenin.
1. J Biol Chem - published March 2, 2021
2. Heier JA, Pokutta S, Dale IW, Kim SK, Hinck AP, Weis WI, Kwiatkowski AV
The role of biofactors in the prevention and treatment of age-related diseases.
1. Biofactors - published March 2, 2021
2. Frank J, Kisters K, Stirban OA, Obeid R, Lorkowski S, Wallert M, Egert S, Podszun MC, Eckert GP, Pettersen JA, Venturelli S, Classen HG, Golombek J
A tumor-specific mechanism of T_reg enrichment mediated by the integrin αvβ8.
1. Sci Immunol - published March 2, 2021
2. Seed RI, Kobayashi K, Ito S, Takasaka N, Cormier A, Jespersen JM, Publicover J, Trilok S, Combes AJ, Chew NW, Chapman J, Krummel MF, Lou J, Marks J, Cheng Y, Baron JL, Nishimura SL
Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2.
1. Proc Natl Acad Sci U S A - published March 2, 2021
2. Liu Y, Hu G, Wang Y, Ren W, Zhao X, Ji F, Zhu Y, Feng F, Gong M, Ju X, Zhu Y, Cai X, Lan J, Guo J, Xie M, Dong L, Zhu Z, Na J, Wu J, Lan X, Xie Y, Wang X, Yuan Z, Zhang R, Ding Q
Protein design-scapes generated by microfluidic DNA assembly elucidate domain coupling in the bacterial histidine kinase CpxA.
1. Proc Natl Acad Sci U S A - published March 2, 2021
2. Clark IC, Mensa B, Ochs CJ, Schmidt NW, Mravic M, Quintana FJ, DeGrado WF, Abate AR
Oligomeric quaternary structure of Escherichia coli and Mycobacterium smegmatis Lhr helicases is nucleated by a novel C-terminal domain composed of five winged-helix modules.
1. Nucleic Acids Res - published March 2, 2021
2. Warren GM, Wang J, Patel DJ, Shuman S
Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote mitotic entry.
1. Nat Commun - published March 2, 2021
2. Tavernier N, Thomas Y, Vigneron S, Maisonneuve P, Orlicky S, Mader P, Regmi SG, Van Hove L, Levinson NM, Gasmi-Seabrook G, Joly N, Poteau M, Velez-Aguilera G, Gavet O, Castro A, Dasso M, Lorca T, Sicheri F, Pintard L
Molecular assemblies of the catalytic domain of SOS with KRas and oncogenic mutants.
1. Proc Natl Acad Sci U S A - published March 2, 2021
2. Moghadamchargari Z, Shirzadeh M, Liu C, Schrecke S, Packianathan C, Russell DH, Zhao M, Laganowsky A
Publisher Correction: The cryo-EM method microcrystal electron diffraction (MicroED).
1. Nat Methods - published March 2, 2021
2. Nannenga BL, Gonen T
Discovery and resistance mechanism of a selective CDK12 degrader.
1. Nat Chem Biol - published March 2, 2021
2. Jiang B, Gao Y, Che J, Lu W, Kaltheuner IH, Dries R, Kalocsay M, Berberich MJ, Jiang J, You I, Kwiatkowski N, Riching KM, Daniels DL, Sorger PK, Geyer M, Zhang T, Gray NS
Configurational Entropy of Folded Proteins and Its Importance for Intrinsically Disordered Proteins.
1. Int J Mol Sci - published March 2, 2021
2. Liu M, Das AK, Lincoff J, Sasmal S, Cheng SY, Vernon RM, Forman-Kay JD, Head-Gordon T
Time resolved phosphoproteomics reveals scaffolding and catalysis-responsive patterns of SHP2-dependent signaling.
1. Elife - published March 2, 2021
2. Vemulapalli V, Chylek LA, Erickson A, Pfeiffer A, Gabriel KH, LaRochelle J, Subramanian K, Cao R, Stegmaier K, Mohseni M, LaMarche MJ, Acker MG, Sorger PK, Gygi SP, Blacklow SC
Elusive Intermediate State Key in the Conversion of ATP Hydrolysis into Useful Work Driving the Ca²⁺ Pump SERCA.
1. J Phys Chem B - published March 2, 2021
2. Thirman J, Rui H, Roux B
Backbone chemical shift spectral assignments of SARS coronavirus-2 non-structural protein nsp9.
1. Biomol NMR Assign - published March 2, 2021
2. F Dudás E, Puglisi R, Korn SM, Alfano C, Bellone ML, Piaz FD, Kelly G, Monaca E, Schlundt A, Schwalbe H, Pastore A
Telegenetics for inherited retinal diseases in the COVID-19 environment.
1. Int J Retina Vitreous - published March 2, 2021
2. Al-Moujahed A, Kumar A, Chemudupati T, Tsang SH, Mahajan VB
Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation.
1. Nat Commun - published March 2, 2021
2. Jette CA, Barnes CO, Kirk SM, Melillo B, Smith AB 3rd, Bjorkman PJ
Two-Dimensional Barriers for Probing Conformational Shifts in Macrocycles.
1. J Am Chem Soc - published March 2, 2021
2. Kobori S, Huh S, Appavoo SD, Yudin AK
Ceramide-1-phosphate transfer protein (CPTP) regulation by phosphoinositides^.
1. J Biol Chem - published March 2, 2021
2. Gao YG, Zhai X, Boldyrev IA, Molotkovsky JG, Patel DJ, Malinina L, Brown RE
Symptoms of Depression in Patients with Chemosensory Disorders.
1. ORL J Otorhinolaryngol Relat Spec - published March 2, 2021
2. Chen B, Benzien C, Faria V, Ning Y, Cuevas M, Linke J, Croy I, Haehner A, Hummel T
Introduction: Drug Resistance.
1. Chem Rev - published March 2, 2021
2. Kurt Yilmaz N, Schiffer CA
Using culturomics and social media data to characterize wildlife consumption.
1. Conserv Biol - published March 2, 2021
2. Li J, Hu Q
Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV-2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations.
1. ACS Cent Sci - published March 2, 2021
2. Zhang CH, Stone EA, Deshmukh M, Ippolito JA, Ghahremanpour MM, Tirado-Rives J, Spasov KA, Zhang S, Takeo Y, Kudalkar SN, Liang Z, Isaacs F, Lindenbach B, Miller SJ, Anderson KS, Jorgensen WL
An Approach for the Real-Time Quantification of Cytosolic Protein-Protein Interactions in Living Cells.
1. ACS Sens - published March 2, 2021
2. Incaviglia I, Frutiger A, Blickenstorfer Y, Treindl F, Ammirati G, Lüchtefeld I, Dreier B, Plückthun A, Vörös J, Reichmuth AM
¹H, ¹³C, and ¹⁵N backbone chemical-shift assignments of SARS-CoV-2 non-structural protein 1 (leader protein).
1. Biomol NMR Assign - published March 2, 2021
2. Wang Y, Kirkpatrick J, Zur Lage S, Korn SM, Neißner K, Schwalbe H, Schlundt A, Carlomagno T
Direct Structural Insights into GABA_A Receptor Pharmacology.
1. Trends Biochem Sci - published March 2, 2021
2. Kim JJ, Hibbs RE
What Every Reader Should Know About Studies Using Electronic Health Record Data but May Be Afraid to Ask.
1. J Med Internet Res - published March 2, 2021
2. Kohane IS, Aronow BJ, Avillach P, Beaulieu-Jones BK, Bellazzi R, Bradford RL, Brat GA, Cannataro M, Cimino JJ, García-Barrio N, Gehlenborg N, Ghassemi M, Gutiérrez-Sacristán A, Hanauer DA, Holmes JH, Hong C, Klann JG, Loh NHW, Luo Y, Mandl KD, Daniar M, Moore JH, Murphy SN, Neuraz A, Ngiam KY, Omenn GS, Palmer N, Patel LP, Pedrera-Jiménez M, Sliz P, South AM, Tan ALM, Taylor DM, Taylor BW, Torti C, Vallejos AK, Wagholikar KB, Consortium For Clinical Characterization Of COVID-19 By EHR (4CE)., Weber GM, Cai T
Novel RT-ddPCR assays for simultaneous quantification of multiple noncoding and coding regions of SARS-CoV-2 RNA.
1. J Virol Methods - published March 2, 2021
2. Telwatte S, Kumar N, Vallejo-Gracia A, Kumar GR, Lu CM, Ott M, Wong JK, Yukl SA
Influenza Virus RNA-Dependent RNA Polymerase and the Host Transcriptional Apparatus.
1. Annu Rev Biochem - published March 2, 2021
2. Krischuns T, Lukarska M, Naffakh N, Cusack S
An in vitro reconstituted U1 snRNP allows the study of the disordered regions of the particle and the interactions with proteins and ligands.
1. Nucleic Acids Res - published March 2, 2021
2. Campagne S, de Vries T, Malard F, Afanasyev P, Dorn G, Dedic E, Kohlbrecher J, Boehringer D, Cléry A, Allain FH
The actomyosin interface contains an evolutionary conserved core and an ancillary interface involved in specificity.
1. Nat Commun - published March 2, 2021
2. Robert-Paganin J, Xu XP, Swift MF, Auguin D, Robblee JP, Lu H, Fagnant PM, Krementsova EB, Trybus KM, Houdusse A, Volkmann N, Hanein D
Author Correction: Design of biologically active binary protein 2D materials.
1. Nature - published March 2, 2021
2. Ben-Sasson AJ, Watson JL, Sheffler W, Johnson MC, Bittleston A, Somasundaram L, Decarreau J, Jiao F, Chen J, Mela I, Drabek AA, Jarrett SM, Blacklow SC, Kaminski CF, Hura GL, De Yoreo JJ, Kollman JM, Ruohola-Baker H, Derivery E, Baker D
Structure-function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting.
1. Nat Commun - published March 2, 2021
2. Du Z, Brown BP, Kim S, Ferguson D, Pavlick DC, Jayakumaran G, Benayed R, Gallant JN, Zhang YK, Yan Y, Red-Brewer M, Ali SM, Schrock AB, Zehir A, Ladanyi M, Smith AW, Meiler J, Lovly CM
Local deuteration enables NMR observation of methyl groups in proteins from eukaryotic and cell-free expression systems.
1. Angew Chem Int Ed Engl - published March 2, 2021
2. Dubey A, Stoyanov N, Viennet T, Chhabra S, Elter S, Borggräfe J, Viegas A, Nowak RP, Burdziev N, Petrov O, Fischer ES, Etzkorn M, Gelev V, Arthanari H
Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice.
1. Nature - published March 2, 2021
2. De Gasparo R, Pedotti M, Simonelli L, Nickl P, Muecksch F, Cassaniti I, Percivalle E, Lorenzi JCC, Mazzola F, Magrì D, Michalcikova T, Haviernik J, Honig V, Mrazkova B, Polakova N, Fortova A, Tureckova J, Iatsiuk V, Di Girolamo S, Palus M, Zudova D, Bednar P, Bukova I, Bianchini F, Mehn D, Nencka R, Strakova P, Pavlis O, Rozman J, Gioria S, Sammartino JC, Giardina F, Gaiarsa S, Pan-Hammarström Q, Barnes CO, Bjorkman PJ, Calzolai L, Piralla A, Baldanti F, Nussenzweig MC, Bieniasz PD, Hatziioannou T, Prochazka J, Sedlacek R, Robbiani DF, Ruzek D, Varani L
Contributions of the Four Essential Entry Glycoproteins to HSV-1 Tropism and the Selection of Entry Routes.
1. mBio - published March 2, 2021
2. Hilterbrand AT, Daly RE, Heldwein EE
AID overexpression leads to aggressive murine CLL and non-Ig mutations that mirror human neoplasms.
1. Blood - published March 2, 2021
2. Morande PE, Yan XJ, Sepulveda-Yanez JH, Seija N, Marquez ME, Sotelo NS, Abreu C, Crispo M, Fernández-Graña G, Rego N, Bois T, Methot SP, Palacios F, Remedi V, Rai KR, Buschiazzo A, Di Noia JM, Navarrete MA, Chiorazzi N, Oppezzo P
Structure analysis suggests Ess1 isomerizes the carboxy-terminal domain of RNA polymerase II via a bivalent anchoring mechanism.
1. Commun Biol - published March 2, 2021
2. Namitz KEW, Zheng T, Canning AJ, Alicea-Velazquez NL, Castañeda CA, Cosgrove MS, Hanes SD
Targeting loss of heterozygosity for cancer-specific immunotherapy.
1. Proc Natl Acad Sci U S A - published March 2, 2021
2. Hwang MS, Mog BJ, Douglass J, Pearlman AH, Hsiue EH, Paul S, DiNapoli SR, Konig MF, Pardoll DM, Gabelli SB, Bettegowda C, Papadopoulos N, Vogelstein B, Zhou S, Kinzler KW
A single intranasal dose of chimpanzee adenovirus-vectored vaccine protects against SARS-CoV-2 infection in rhesus macaques.
1. Cell Rep Med - published March 1, 2021
2. Hassan AO, Feldmann F, Zhao H, Curiel DT, Okumura A, Tang-Huau TL, Case JB, Meade-White K, Callison J, Chen RE, Lovaglio J, Hanley PW, Scott DP, Fremont DH, Feldmann H, Diamond MS
Comparative analysis reveals the species-specific genetic determinants of ACE2 required for SARS-CoV-2 entry.
1. PLoS Pathog - published March 1, 2021
2. Ren W, Zhu Y, Wang Y, Shi H, Yu Y, Hu G, Feng F, Zhao X, Lan J, Wu J, Kenney DJ, Douam F, Tong Y, Zhong J, Xie Y, Wang X, Yuan Z, Zhou D, Zhang R, Ding Q
Odontoblast TRPC5 channels signal cold pain in teeth.
1. Sci Adv - published March 1, 2021
2. Bernal L, Sotelo-Hitschfeld P, König C, Sinica V, Wyatt A, Winter Z, Hein A, Touska F, Reinhardt S, Tragl A, Kusuda R, Wartenberg P, Sclaroff A, Pfeifer JD, Ectors F, Dahl A, Freichel M, Vlachova V, Brauchi S, Roza C, Boehm U, Clapham DE, Lennerz JK, Zimmermann K
Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein.
1. Cell - published March 1, 2021
2. Suryadevara N, Shrihari S, Gilchuk P, VanBlargan LA, Binshtein E, Zost SJ, Nargi RS, Sutton RE, Winkler ES, Chen EC, Fouch ME, Davidson E, Doranz BJ, Chen RE, Shi PY, Carnahan RH, Thackray LB, Diamond MS, Crowe JE Jr
A cryo-electron tomography workflow reveals protrusion-mediated shedding on injured plasma membrane.
1. Sci Adv - published March 1, 2021
2. Mageswaran SK, Yang WY, Chakrabarty Y, Oikonomou CM, Jensen GJ
Molecular basis of C-S bond cleavage in the glycyl radical enzyme isethionate sulfite-lyase.
1. Cell Chem Biol - published March 1, 2021
2. Dawson CD, Irwin SM, Backman LRF, Le C, Wang JX, Vennelakanti V, Yang Z, Kulik HJ, Drennan CL, Balskus EP
Microcrystal Electron Diffraction of Small Molecules.
1. J Vis Exp - published March 1, 2021
2. Martynowycz MW, Gonen T
Classical molecular dynamics.
1. J Chem Phys - published March 1, 2021
2. Brooks CL 3rd, Case DA, Plimpton S, Roux B, van der Spoel D, Tajkhorshid E
Solving the α-helix correspondence problem at medium-resolution Cryo-EM maps through modeling and 3D matching.
1. J Mol Graph Model - published March 1, 2021
2. Behkamal B, Naghibzadeh M, Pagnani A, Saberi MR, Al Nasr K
Potent Trivalent Inhibitors of Thrombin through Hybridization of Salivary Sulfopeptides from Hematophagous Arthropods.
1. Angew Chem Int Ed Engl - published March 1, 2021
2. Agten SM, Watson EE, Ripoll-Rozada J, Dowman LJ, Wu MCL, Alwis I, Jackson SP, Pereira PJB, Payne RJ
Mechanisms of nonvesicular lipid transport.
1. J Cell Biol - published March 1, 2021
2. Reinisch KM, Prinz WA
Design of Alphavirus Virus-Like Particles Presenting Circumsporozoite Junctional Epitopes That Elicit Protection against Malaria.
1. Vaccines (Basel) - published March 1, 2021
2. Francica JR, Shi W, Chuang GY, Chen SJ, Da Silva Pereira L, Farney SK, Flynn BJ, Ou L, Stephens T, Tsybovsky Y, Wang LT, Anderson A, Beck Z, Dillon M, Idris AH, Hurlburt N, Liu T, Zhang B, Alving CR, Matyas GR, Pancera M, Mascola JR, Kwong PD, Seder RA
Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
1. Cell Host Microbe - published March 1, 2021
2. Cerutti G, Guo Y, Zhou T, Gorman J, Lee M, Rapp M, Reddem ER, Yu J, Bahna F, Bimela J, Huang Y, Katsamba PS, Liu L, Nair MS, Rawi R, Olia AS, Wang P, Zhang B, Chuang GY, Ho DD, Sheng Z, Kwong PD, Shapiro L
Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class.
1. Cell Rep - published March 1, 2021
2. Rapp M, Guo Y, Reddem ER, Yu J, Liu L, Wang P, Cerutti G, Katsamba P, Bimela JS, Bahna FA, Mannepalli SM, Zhang B, Kwong PD, Huang Y, Ho DD, Shapiro L, Sheng Z
Isolation and characterization of extracellular vesicles produced by cell lines.
1. STAR Protoc - published March 1, 2021
2. Wang F, Cerione RA, Antonyak MA
Crystal structure of the nonclassical cadherin-17 N-terminus and implications for its adhesive binding mechanism.
1. Acta Crystallogr F Struct Biol Commun - published March 1, 2021
2. Gray ME, Sotomayor M
Coronavirus-Specific Antibody Cross Reactivity in Rhesus Macaques Following SARS-CoV-2 Vaccination and Infection.
1. J Virol - published March 1, 2021
2. Jacob-Dolan C, Feldman J, McMahan K, Yu J, Zahn R, Wegmann F, Schuitemaker H, Schmidt AG, Barouch DH
Natural products that target the cell envelope.
1. Curr Opin Microbiol - published March 1, 2021
2. Page JE, Walker S
eIF2B conformation and assembly state regulates the integrated stress response.
1. Elife - published March 1, 2021
2. Schoof M, Boone M, Wang L, Lawrence R, Frost A, Walter P
Expression and purification of active human kinases using Pichia pastoris as a general-purpose host.
1. Protein Expr Purif - published March 1, 2021
2. Abdel Aziz MH, Fan Y, Liu L, Moasser MM, Fu H, Jura N, Arkin MR
iMATCH: an integrated modular assembly system for therapeutic combination high-capacity adenovirus gene therapy.
1. Mol Ther Methods Clin Dev - published March 1, 2021
2. Brücher D, Kirchhammer N, Smith SN, Schumacher J, Schumacher N, Kolibius J, Freitag PC, Schmid M, Weiss F, Keller C, Grove M, Greber UF, Zippelius A, Plückthun A
The dimeric Golgi protein Gorab binds to Sas6 as a monomer to mediate centriole duplication.
1. Elife - published March 1, 2021
2. Fatalska A, Stepinac E, Richter M, Kovacs L, Pietras Z, Puchinger M, Dong G, Dadlez M, Glover DM
Targeting a neoantigen derived from a common TP53 mutation.
1. Science - published March 1, 2021
2. Hsiue EH, Wright KM, Douglass J, Hwang MS, Mog BJ, Pearlman AH, Paul S, DiNapoli SR, Konig MF, Wang Q, Schaefer A, Miller MS, Skora AD, Azurmendi PA, Murphy MB, Liu Q, Watson E, Li Y, Pardoll DM, Bettegowda C, Papadopoulos N, Kinzler KW, Vogelstein B, Gabelli SB, Zhou S
Inhibition of CRISPR-Cas12a DNA targeting by nucleosomes and chromatin.
1. Sci Adv - published March 1, 2021
2. Strohkendl I, Saifuddin FA, Gibson BA, Rosen MK, Russell R, Finkelstein IJ
Cyclic Analogues of the Chemerin C-Terminus Mimic a Loop Conformation Essential for Activating the Chemokine-like Receptor 1.
1. J Med Chem - published March 1, 2021
2. Fischer TF, Schoeder CT, Zellmann T, Stichel J, Meiler J, Beck-Sickinger AG
A vulnerable, membrane-proximal site in human respiratory syncytial virus F revealed by a prefusion-specific single-domain antibody.
1. J Virol - published March 1, 2021
2. Rossey I, Hsieh CL, Sedeyn K, Ballegeer M, Schepens B, Mclellan JS, Saelens X
Targeting multiple enzymes in vitamin K metabolism for anticoagulation.
1. J Thromb Haemost - published March 1, 2021
2. Li W
Bispecific antibodies targeting mutant RAS neoantigens.
1. Sci Immunol - published March 1, 2021
2. Douglass J, Hsiue EH, Mog BJ, Hwang MS, DiNapoli SR, Pearlman AH, Miller MS, Wright KM, Azurmendi PA, Wang Q, Paul S, Schaefer A, Skora AD, Molin MD, Konig MF, Liu Q, Watson E, Li Y, Murphy MB, Pardoll DM, Bettegowda C, Papadopoulos N, Gabelli SB, Kinzler KW, Vogelstein B, Zhou S
Modeling Immunity with Rosetta: Methods for Antibody and Antigen Design.
1. Biochemistry - published March 1, 2021
2. Schoeder CT, Schmitz S, Adolf-Bryfogle J, Sevy AM, Finn JA, Sauer MF, Bozhanova NG, Mueller BK, Sangha AK, Bonet J, Sheehan JH, Kuenze G, Marlow B, Smith ST, Woods H, Bender BJ, Martina CE, Del Alamo D, Kodali P, Gulsevin A, Schief WR, Correia BE, Crowe JE Jr, Meiler J, Moretti R
TCR beta chain-directed bispecific antibodies for the treatment of T-cell cancers.
1. Sci Transl Med - published March 1, 2021
2. Paul S, Pearlman AH, Douglass J, Mog BJ, Hsiue EH, Hwang MS, DiNapoli SR, Konig MF, Brown PA, Wright KM, Sur S, Gabelli SB, Li Y, Ghiaur G, Pardoll D, Papadopoulos N, Bettegowda C, Kinzler KW, Zhou S, Vogelstein B
REGALS: a general method to deconvolve X-ray scattering data from evolving mixtures.
1. IUCrJ - published March 1, 2021
2. Meisburger SP, Xu D, Ando N
Protein Substrates Engage the Lumen of O-GlcNAc Transferase's Tetratricopeptide Repeat Domain in Different Ways.
1. Biochemistry - published March 1, 2021
2. Joiner CM, Hammel FA, Janetzko J, Walker S
Development of single-stranded DNA bisintercalating inhibitors of primase DnaG as antibiotics.
1. ChemMedChem - published March 1, 2021
2. Green KD, Punetha A, Chandrika NT, Hou C, Garneau-Tsodikova S, Tsodikov OV
Rapid tilt-series method for cryo-electron tomography: Characterizing stage behavior during FISE acquisition.
1. J Struct Biol - published March 1, 2021
2. Chreifi G, Chen S, Jensen GJ
Differential cellular responses to adhesive interactions with galectin-8 and fibronectin coated substrates.
1. J Cell Sci - published March 1, 2021
2. Li W, Sancho A, Chung WL, Vinik Y, Groll J, Zick Y, Medalia O, Bershadsky AD, Geiger B
The Matrix Revisited: Opening Night for the Pel Polysaccharide Across Eubacterial Kingdoms.
1. Microbiol Insights - published March 1, 2021
2. Whitfield GB, Howell PL
Crystal structure of P. falciparum Cpn60 bound to ATP reveals an open dynamic conformation before substrate binding.
1. Sci Rep - published March 1, 2021
2. Nguyen B, Ma R, Tang WK, Shi D, Tolia NH
SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19.
1. Sci Transl Med - published March 1, 2021
2. Perez-Bermejo JA, Kang S, Rockwood SJ, Simoneau CR, Joy DA, Silva AC, Ramadoss GN, Flanigan WR, Fozouni P, Li H, Chen PY, Nakamura K, Whitman JD, Hanson PJ, McManus BM, Ott M, Conklin BR, McDevitt TC
The Antifungal Drug Isavuconazole Inhibits the Replication of Human Cytomegalovirus (HCMV) and Acts Synergistically with Anti-HCMV Drugs.
1. Antiviral Res - published March 1, 2021
2. Mercorelli B, Celegato M, Luganini A, Gribaudo G, Lepesheva GI, Loregian A
In vitro characterization of engineered red blood cells as viral traps against HIV-1 and SARS-CoV-2.
1. Mol Ther Methods Clin Dev - published March 1, 2021
2. Hoffmann MAG, Kieffer C, Bjorkman PJ
Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes.
1. PLoS Biol - published March 1, 2021
2. Ravindra NG, Alfajaro MM, Gasque V, Huston NC, Wan H, Szigeti-Buck K, Yasumoto Y, Greaney AM, Habet V, Chow RD, Chen JS, Wei J, Filler RB, Wang B, Wang G, Niklason LE, Montgomery RR, Eisenbarth SC, Chen S, Williams A, Iwasaki A, Horvath TL, Foxman EF, Pierce RW, Pyle AM, van Dijk D, Wilen CB
Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion.
1. J Med Chem - published March 1, 2021
2. Cockerill GS, Angell RM, Bedernjak A, Chuckowree I, Fraser I, Gascon-Simorte J, Gilman MSA, Good JAD, Harland R, Johnson SM, Ludes-Meyers JH, Littler E, Lumley J, Lunn G, Mathews N, McLellan JS, Paradowski M, Peeples ME, Scott C, Tait D, Taylor G, Thom M, Thomas E, Villalonga Barber C, Ward SE, Watterson D, Williams G, Young P, Powell K
Surface proteomics reveals CD72 as a target for in vitro-evolved nanobody-based CAR-T cells in KMT2A/MLL1-rearranged B-ALL.
1. Cancer Discov - published March 1, 2021
2. Nix MA, Mandal K, Geng H, Paranjape N, Lin YT, Rivera J, Marcoulis M, White KL, Whitman JD, Bapat SP, Parker KR, Ramirez J, Deucher A, Phojanokong P, Steri V, Fattahi F, Hann B, Satpathy AT, Manglik A, Stieglitz E, Wiita AP
Prediction of amphipathic helix-Membrane interactions with Rosetta.
1. PLoS Comput Biol - published March 1, 2021
2. Gulsevin A, Meiler J
A genome-wide CRISPR screen identifies UFMylation and TRAMP-like complexes as host factors required for hepatitis A virus infection.
1. Cell Rep - published March 1, 2021
2. Kulsuptrakul J, Wang R, Meyers NL, Ott M, Puschnik AS
Structural impact on SARS-CoV-2 spike protein by D614G substitution.
1. Science - published March 1, 2021
2. Zhang J, Cai Y, Xiao T, Lu J, Peng H, Sterling SM, Walsh RM Jr, Rits-Volloch S, Zhu H, Woosley AN, Yang W, Sliz P, Chen B
Author Correction: Self-assembly and regulation of protein cages from pre-organised coiled-coil modules.
1. Nat Commun - published March 1, 2021
2. Lapenta F, Aupič J, Vezzoli M, Strmšek Ž, Da Vela S, Svergun DI, Carazo JM, Melero R, Jerala R
Structure and gating mechanism of the α7 nicotinic acetylcholine receptor.
1. Cell - published March 1, 2021
2. Noviello CM, Gharpure A, Mukhtasimova N, Cabuco R, Baxter L, Borek D, Sine SM, Hibbs RE
A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies.
1. Nat Commun - published March 1, 2021
2. Wang C, van Haperen R, Gutiérrez-Álvarez J, Li W, Okba NMA, Albulescu I, Widjaja I, van Dieren B, Fernandez-Delgado R, Sola I, Hurdiss DL, Daramola O, Grosveld F, van Kuppeveld FJM, Haagmans BL, Enjuanes L, Drabek D, Bosch BJ
DNA-driven condensation assembles the meiotic DNA break machinery.
1. Nature - published March 1, 2021
2. Claeys Bouuaert C, Pu S, Wang J, Oger C, Daccache D, Xie W, Patel DJ, Keeney S
Structure-based decoupling of the pro- and anti-inflammatory functions of interleukin-10.
1. Science - published March 1, 2021
2. Saxton RA, Tsutsumi N, Su LL, Abhiraman GC, Mohan K, Henneberg LT, Aduri NG, Gati C, Garcia KC
Facile Synthesis of a Croconaine-Based Nanoformulation for Optoacoustic Imaging and Photothermal Therapy.
1. Adv Healthc Mater - published March 1, 2021
2. Liu N, O'Connor P, Gujrati V, Gorpas D, Glasl S, Blutke A, Walch A, Kleigrewe K, Sattler M, Plettenburg O, Ntziachristos V
Phenotypic approaches to small-molecule discovery in chemical biology.
1. Cell Chem Biol - published March 1, 2021
2. Wagner BK, Dey M
The groovy TMEM16 family: molecular mechanisms of lipid scrambling and ion conduction.
1. J Mol Biol - published March 1, 2021
2. Kalienkova V, Clerico Mosina V, Paulino C
Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity.
1. Cell - published March 1, 2021
2. Garcia-Beltran WF, Lam EC, St Denis K, Nitido AD, Garcia ZH, Hauser BM, Feldman J, Pavlovic MN, Gregory DJ, Poznansky MC, Sigal A, Schmidt AG, Iafrate AJ, Naranbhai V, Balazs AB
A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes.
1. Nat Commun - published March 1, 2021
2. Coelho CH, Tang WK, Burkhardt M, Galson JD, Muratova O, Salinas ND, Alves E Silva TL, Reiter K, MacDonald NJ, Nguyen V, Herrera R, Shimp R, Narum DL, Byrne-Steele M, Pan W, Hou X, Brown B, Eisenhower M, Han J, Jenkins BJ, Doritchamou JYA, Smelkinson MG, Vega-Rodríguez J, Trück J, Taylor JJ, Sagara I, Renn JP, Tolia NH, Duffy PE
Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium.
1. Commun Biol - published March 1, 2021
2. Gandhi AK, Sun ZJ, Kim WM, Huang YH, Kondo Y, Bonsor DA, Sundberg EJ, Wagner G, Kuchroo VK, Petsko GA, Blumberg RS
Free-Radical Membrane Protein Footprinting by Photolysis of Perfluoroisopropyl Iodide Partitioned to Detergent Micelle by Sonication.
1. Angew Chem Int Ed Engl - published March 1, 2021
2. Cheng M, Guo C, Li W, Gross ML
Integrating 3D structural information into systems biology.
1. J Biol Chem - published March 1, 2021
2. Murray D, Petrey D, Honig B
Highlighting membrane protein structure and function: A celebration of the Protein Data Bank.
1. J Biol Chem - published March 1, 2021
2. Li F, Egea PF, Vecchio AJ, Asial I, Gupta M, Paulino J, Bajaj R, Dickinson MS, Ferguson-Miller S, Monk BC, Stroud RM