Member Publications
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26 Member Publications for February
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The COVID19-NMR Consortium: A Public Report on the Impact of this New Global Collaboration.
- Angew Chem Int Ed Engl - published February 7, 2023
- Duchardt-Ferner E, Ferner J, Fürtig B, Hengesbach M, Richter C, Schlundt A, Sreeramulu S, Wacker A, Weigand JE, Wirmer-Bartoschek J, Schwalbe H
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Learning Correlations between Internal Coordinates to Improve 3D Cartesian Coordinates for Proteins.
- J Chem Theory Comput - published February 7, 2023
- Li J, Zhang O, Lee S, Namini A, Liu ZH, Teixeira JMC, Forman-Kay JD, Head-Gordon T
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Deep neural network automated segmentation of cellular structures in volume electron microscopy.
- J Cell Biol - published February 6, 2023
- Gallusser B, Maltese G, Di Caprio G, Vadakkan TJ, Sanyal A, Somerville E, Sahasrabudhe M, O'Connor J, Weigert M, Kirchhausen T
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Distinct Energy-Coupling Factor Transporter Subunits Enable Flavin Acquisition and Extracytosolic Trafficking for Extracellular Electron Transfer in Listeria monocytogenes.
- mBio - published February 6, 2023
- Rivera-Lugo R, Huang S, Lee F, Méheust R, Iavarone AT, Sidebottom AM, Oldfield E, Portnoy DA, Light SH
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Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder.
- Nat Commun - published February 6, 2023
- Kordon SP, Dutka P, Adamska JM, Bandekar SJ, Leon K, Erramilli SK, Adams B, Li J, Kossiakoff AA, Araç D
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Shark nanobodies with potent SARS-CoV-2 neutralizing activity and broad sarbecovirus reactivity.
- Nat Commun - published February 3, 2023
- Chen WH, Hajduczki A, Martinez EJ, Bai H, Matz H, Hill TM, Lewitus E, Chang WC, Dawit L, Peterson CE, Rees PA, Ajayi AB, Golub ES, Swafford I, Dussupt V, David S, Mayer SV, Soman S, Kuklis C, Corbitt C, King J, Choe M, Sankhala RS, Thomas PV, Zemil M, Wieczorek L, Hart T, Duso D, Kummer L, Yan L, Sterling SL, Laing ED, Broder CC, Williams JK, Davidson E, Doranz BJ, Krebs SJ, Polonis VR, Paquin-Proulx D, Rolland M, Reiley WW, Gromowski GD, Modjarrad K, Dooley H, Joyce MG
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Discovery of a Potent and Selective STAT5 PROTAC Degrader with Strong Antitumor Activity In Vivo in Acute Myeloid Leukemia.
- J Med Chem - published February 3, 2023
- Kaneshige A, Bai L, Wang M, McEachern D, Meagher JL, Xu R, Kirchhoff PD, Wen B, Sun D, Stuckey JA, Wang S
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Synthesis and Biophysical Properties of Phosphorodiamidate Piperidino Oligomers.
- Org Lett - published February 3, 2023
- Ghosh A, Akabane-Nakata M, Kundu J, Harp JM, Madaoui M, Egli M, Manoharan M, Sinha S
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Aim18p and Aim46p are chalcone isomerase (CHI)-domain-containing mitochondrial hemoproteins in Saccharomyces cerevisiae.
- J Biol Chem - published February 3, 2023
- Schmitz JM, Wolters JF, Murray NH, Guerra RM, Bingman CA, Hittinger CT, Pagliarini DJ
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A selective small-molecule STAT5 PROTAC degrader capable of achieving tumor regression in vivo.
- Nat Chem Biol - published February 2, 2023
- Kaneshige A, Bai L, Wang M, McEachern D, Meagher JL, Xu R, Wang Y, Jiang W, Metwally H, Kirchhoff PD, Zhao L, Jiang H, Wang M, Wen B, Sun D, Stuckey JA, Wang S
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Naturally acquired antibodies to gametocyte antigens are associated with reduced transmission of Plasmodium vivax gametocytes to Anopheles arabiensis mosquitoes.
- Front Cell Infect Microbiol - published February 2, 2023
- Tebeje SK, Chali W, Hailemeskel E, Ramjith J, Gashaw A, Ashine T, Nebret D, Esayas E, Emiru T, Tsegaye T, Teelen K, Lanke K, Takashima E, Tsuboi T, Salinas ND, Tolia NH, Narum D, Drakeley C, Witkowski B, Vantaux A, Jore MM, Stone WJR, Hansen IS, Tadesse FG, Bousema T
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WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma.
- Genes Dev - published February 2, 2023
- Mitchell K, Sprowls SA, Arora S, Shakya S, Silver DJ, Goins CM, Wallace L, Roversi G, Schafer R, Kay K, Miller TE, Lauko A, Bassett J, Kashyap A, D'Amato Kass J, Mulkearns-Hubert EE, Johnson S, Alvarado J, Rich JN, Holland EC, Paddison PJ, Patel AP, Stauffer SR, Hubert CG, Lathia JD
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Antibody-based protection against respiratory syncytial virus in mice and their offspring through vectored immunoprophylaxis.
- Gene Ther - published February 2, 2023
- Rghei AD, Yates JGE, Lopes JA, Zhan X, Guilleman MM, Pei Y, van Lieshout LP, Santry LA, Bridle BW, Karimi K, Thompson B, Susta L, Crowe JE Jr, Wootton SK
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RCSB Protein Data Bank: Efficient Searching and Simultaneous Access to One Million Computed Structure Moddels Alongside the PDB Structures Enabled by Architectural Advances.
- J Mol Biol - published February 2, 2023
- Bittrich S, Bhikadiya C, Bi C, Chao H, Duarte JM, Dutta S, Fayazi M, Henry J, Khokhriakov I, Lowe R, Piehl DW, Segura J, Vallat B, Voigt M, Westbrook JD, Burley SK, Rose Y
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Recognition of transcription terminators during retrotransposition: How to keep a group II intron quiet.
- Mol Cell - published February 2, 2023
- Haack DB, Toor N
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The F-box protein UFO controls flower development by redirecting the master transcription factor LEAFY to new cis-elements.
- Nat Plants - published February 2, 2023
- Rieu P, Turchi L, Thévenon E, Zarkadas E, Nanao M, Chahtane H, Tichtinsky G, Lucas J, Blanc-Mathieu R, Zubieta C, Schoehn G, Parcy F
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Glycoside hydrolase processing of the Pel polysaccharide alters biofilm biomechanics and Pseudomonas aeruginosa virulence.
- NPJ Biofilms Microbiomes - published February 2, 2023
- Razvi E, Whitfield GB, Reichhardt C, Dreifus JE, Willis AR, Gluscencova OB, Gloag ES, Awad TS, Rich JD, da Silva DP, Bond W, Le Mauff F, Sheppard DC, Hatton BD, Stoodley P, Reinke AW, Boulianne GL, Wozniak DJ, Harrison JJ, Parsek MR, Howell PL
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N-terminal domain on dystroglycan enables LARGE1 to extend matriglycan on α-dystroglycan and prevents muscular dystrophy.
- Elife - published February 1, 2023
- Okuma H, Hord JM, Chandel I, Venzke D, Anderson ME, Walimbe AS, Joseph S, Gastel Z, Hara Y, Saito F, Matsumura K, Campbell KP
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Formation and characterization of BMP2/GDF5 and BMP4/GDF5 heterodimers.
- BMC Biol - published February 1, 2023
- Gipson GR, Nolan K, Kattamuri C, Kenny AP, Agricola Z, Edwards NA, Zinski J, Czepnik M, Mullins MC, Zorn AM, Thompson TB
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Purification and structure of luminal domain C of human Niemann-Pick C1 protein.
- Acta Crystallogr F Struct Biol Commun - published February 1, 2023
- Odongo L, Zadrozny KK, Diehl WE, Luban J, White JM, Ganser-Pornillos BK, Tamm LK, Pornillos O
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Anti-CRISPR protein AcrIIC5 inhibits CRISPR-Cas9 by occupying the target DNA binding pocket.
- J Mol Biol - published February 1, 2023
- Hwang S, Shah M, Garcia B, Hashem N, Davidson AR, Moraes TF, Maxwell KL
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Heparin is essential for optimal cell signaling by FGF21 and for regulation of βKlotho cellular stability.
- Proc Natl Acad Sci U S A - published February 1, 2023
- An SJ, Mohanty J, Tome F, Suzuki Y, Lax I, Schlessinger J
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Horizontal transfer of the rfb cluster in Leptospira is a genetic determinant of serovar identity.
- Life Sci Alliance - published February 1, 2023
- Nieves C, Vincent AT, Zarantonelli L, Picardeau M, Veyrier FJ, Buschiazzo A
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Linking medicinal cannabis to autotaxin-lysophosphatidic acid signaling.
- Life Sci Alliance - published February 1, 2023
- Eymery MC, McCarthy AA, Hausmann J
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Structural basis for substrate selection by the SARS-CoV-2 replicase.
- Nature - published February 1, 2023
- Malone BF, Perry JK, Olinares PDB, Lee HW, Chen J, Appleby TC, Feng JY, Bilello JP, Ng H, Sotiris J, Ebrahim M, Chua EYD, Mendez JH, Eng ET, Landick R, Götte M, Chait BT, Campbell EA, Darst SA
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Acyclic (S)-Glycol Nucleic Acid (S-GNA) Modification of siRNAs Improves the Safety of RNAi Therapeutics While Maintaining Potency.
- RNA - published February 1, 2023
- Egli M, Schlegel MK, Manoharan M