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40 Member Publications for October

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SH2 Domain Binding: Diverse FLVRs of Partnership.
1. Front Endocrinol (Lausanne) - published October 12, 2020
2. Jaber Chehayeb R, Boggon TJ
Assessing multiple score functions in Rosetta for drug discovery.
1. PLoS One - published October 12, 2020
2. Smith ST, Meiler J
Garcinol Is an HDAC11 Inhibitor.
1. ACS Chem Biol - published October 9, 2020
2. Son SI, Su D, Ho TT, Lin H
Specific and direct modulation of the interaction between adhesion GPCR GPR56/ADGRG1 and tissue transglutaminase 2 using synthetic ligands.
1. Sci Rep - published October 9, 2020
2. Salzman GS, Zhang S, Fernandez CG, Araç D, Koide S
A versatile soluble siglec scaffold for sensitive and quantitative detection of glycan ligands.
1. Nat Commun - published October 9, 2020
2. Rodrigues E, Jung J, Park H, Loo C, Soukhtehzari S, Kitova EN, Mozaneh F, Daskhan G, Schmidt EN, Aghanya V, Sarkar S, Streith L, St Laurent CD, Nguyen L, Julien JP, West LJ, Williams KC, Klassen JS, Macauley MS
Concerning P450 evolution: Structural Analyses Support Bacterial Origin of Sterol 14α-Demethylases.
1. Mol Biol Evol - published October 8, 2020
2. Lamb DC, Hargrove TY, Zhao B, Wawrzak Z, Goldstone JV, Nes WD, Kelly SL, Waterman MR, Stegeman JJ, Lepesheva GI
Comparative genomics of Clostridioides difficile toxinotypes identifies module-based toxin gene evolution.
1. Microb Genom - published October 8, 2020
2. Janezic S, Dingle K, Alvin J, Accetto T, Didelot X, Crook DW, Lacy DB, Rupnik M
Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies.
1. Nat Commun - published October 8, 2020
2. Rujas E, Cui H, Sicard T, Semesi A, Julien JP
Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients.
1. Sci Immunol - published October 8, 2020
2. Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yue FY, Marin LM, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, McGeer AJ, Gommerman JL, Gingras AC
Author Correction: PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis.
1. Nat Cell Biol - published October 8, 2020
2. Hou J, Zhao R, Xia W, Chang CW, You Y, Hsu JM, Nie L, Chen Y, Wang YC, Liu C, Wang WJ, Wu Y, Ke B, Hsu JL, Huang K, Ye Z, Yang Y, Xia X, Li Y, Li CW, Shao B, Tainer JA, Hung MC
Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients.
1. Sci Immunol - published October 8, 2020
2. Iyer AS, Jones FK, Nodoushani A, Kelly M, Becker M, Slater D, Mills R, Teng E, Kamruzzaman M, Garcia-Beltran WF, Astudillo M, Yang D, Miller TE, Oliver E, Fischinger S, Atyeo C, Iafrate AJ, Calderwood SB, Lauer SA, Yu J, Li Z, Feldman J, Hauser BM, Caradonna TM, Branda JA, Turbett SE, LaRocque RC, Mellon G, Barouch DH, Schmidt AG, Azman AS, Alter G, Ryan ET, Harris JB, Charles RC
CryoEM structure of the type IVa pilus secretin required for natural competence in Vibrio cholerae.
1. Nat Commun - published October 8, 2020
2. Weaver SJ, Ortega DR, Sazinsky MH, Dalia TN, Dalia AB, Jensen GJ
Microglia-organized scar-free spinal cord repair in neonatal mice.
1. Nature - published October 7, 2020
2. Li Y, He X, Kawaguchi R, Zhang Y, Wang Q, Monavarfeshani A, Yang Z, Chen B, Shi Z, Meng H, Zhou S, Zhu J, Jacobi A, Swarup V, Popovich PG, Geschwind DH, He Z
A STAT3 palmitoylation cycle promotes T_H17 differentiation and colitis.
1. Nature - published October 7, 2020
2. Zhang M, Zhou L, Xu Y, Yang M, Xu Y, Komaniecki GP, Kosciuk T, Chen X, Lu X, Zou X, Linder ME, Lin H
Coordination of Grp1 recruitment mechanisms by its phosphorylation.
1. Mol Biol Cell - published October 7, 2020
2. Li J, Lambright DG, Hsu VW
Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19.
1. Nat Immunol - published October 7, 2020
2. Woodruff MC, Ramonell RP, Nguyen DC, Cashman KS, Saini AS, Haddad NS, Ley AM, Kyu S, Howell JC, Ozturk T, Lee S, Suryadevara N, Case JB, Bugrovsky R, Chen W, Estrada J, Morrison-Porter A, Derrico A, Anam FA, Sharma M, Wu HM, Le SN, Jenks SA, Tipton CM, Staitieh B, Daiss JL, Ghosn E, Diamond MS, Carnahan RH, Crowe JE Jr, Hu WT, Lee FE, Sanz I
PilY1 and minor pilins form a complex priming the type IVa pilus in Myxococcus xanthus.
1. Nat Commun - published October 7, 2020
2. Treuner-Lange A, Chang YW, Glatter T, Herfurth M, Lindow S, Chreifi G, Jensen GJ, Søgaard-Andersen L
Uncovering DNA-PKcs ancient phylogeny, unique sequence motifs and insights for human disease.
1. Prog Biophys Mol Biol - published October 6, 2020
2. Lees-Miller JP, Cobban A, Katsonis P, Bacolla A, Tsutakawa SE, Hammel M, Meek K, Anderson DW, Lichtarge O, Tainer JA, Lees-Miller SP
Computationally Designed Cyclic Peptides Derived from an Antibody Loop Increase Breadth of Binding for Influenza Variants.
1. Structure - published October 6, 2020
2. Sevy AM, Gilchuk IM, Brown BP, Bozhanova NG, Nargi R, Jensen M, Meiler J, Crowe JE Jr
Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29.
1. Nat Commun - published October 6, 2020
2. Crawley-Snowdon H, Yang JC, Zaccai NR, Davis LJ, Wartosch L, Herman EK, Bright NA, Swarbrick JS, Collins BM, Jackson LP, Seaman MNJ, Luzio JP, Dacks JB, Neuhaus D, Owen DJ
Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers.
1. Elife - published October 5, 2020
2. Wan W, Clarke M, Norris MJ, Kolesnikova L, Koehler A, Bornholdt ZA, Becker S, Ollman-Saphire E, Briggs JA
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality.
1. J Cell Biol - published October 5, 2020
2. Mast FD, Navare AT, van der Sloot AM, Coulombe-Huntington J, Rout MP, Baliga NS, Kaushansky A, Chait BT, Aderem A, Rice CM, Sali A, Tyers M, Aitchison JD
Reply to: "Does PCNA diffusion on DNA follow a rotation-coupled translation mechanism?"
1. Nat Commun - published October 5, 2020
2. De March M, Onesti S, De Biasio A
Shared requirements for key residues in the antibiotic resistance enzymes ErmC and ErmE suggest a common mode of RNA recognition.
1. J Biol Chem - published October 5, 2020
2. Rowe SJ, Mecaskey RJ, Nasef M, Talton RC, Sharkey RE, Halliday JC, Dunkle JA
ACE2-containing extracellular vesicles and exomeres bind the SARS-CoV-2 spike protein.
1. Gastroenterology - published October 3, 2020
2. Zhang Q, Jeppesen DK, Higginbotham JN, Franklin JL, Crowe JE Jr, Coffey RJ
A time-resolved cryo-EM Study of S. cerevisiae 80S Ribosome Protein Composition in Response to a Change in Carbon Source.
1. Proteomics - published October 2, 2020
2. Sun M, Shen B, Li W, Samir P, Browne CM, Link AJ, Frank J
Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex.
1. Nat Commun - published October 2, 2020
2. Glavier M, Puvanendran D, Salvador D, Decossas M, Phan G, Garnier C, Frezza E, Cece Q, Schoehn G, Picard M, Taveau JC, Daury L, Broutin I, Lambert O
Comparison of tyrosine kinase domain properties for the neurotrophin receptors TrkA and TrkB.
1. Biochem J - published October 1, 2020
2. Artim SC, Kiyatkin A, Lemmon MA
Cryo-electron microscopy structure of the 70S ribosome from Enterococcus faecalis.
1. Sci Rep - published October 1, 2020
2. Murphy EL, Singh KV, Avila B, Kleffmann T, Gregory ST, Murray BE, Krause KL, Khayat R, Jogl G
The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase.
1. Sci Adv - published October 1, 2020
2. Seervai RNH, Jangid RK, Karki M, Tripathi DN, Jung SY, Kearns SE, Verhey KJ, Cianfrocco MA, Millis BA, Tyska MJ, Mason FM, Rathmell WK, Park IY, Dere R, Walker CL
The N-terminal length and side-chain composition of CXCL13 affect crystallization, structure and functional activity.
1. Acta Crystallogr D Struct Biol - published October 1, 2020
2. Rosenberg EM Jr, Herrington J, Rajasekaran D, Murphy JW, Pantouris G, Lolis EJ
Sex Does Not Influence Visual Outcomes After Blast-Mediated Traumatic Brain Injury but IL-1 Pathway Mutations Confer Partial Rescue.
1. Invest Ophthalmol Vis Sci - published October 1, 2020
2. Evans LP, Boehme N, Wu S, Burghardt EL, Akurathi A, Todd BP, Newell EA, Ferguson PJ, Mahajan VB, Dutca LM, Harper MM, Bassuk AG
Human ferroportin mediates proton-coupled active transport of iron.
1. Blood Adv - published October 1, 2020
2. Li S, Yang Y, Li W
Animal-free alternatives and the antibody iceberg.
1. Nat Biotechnol - published October 1, 2020
2. Gray A, Bradbury ARM, Knappik A, Plückthun A, Borrebaeck CAK, Dübel S
Retinal Manifestations of Mitochondrial Oxidative Phosphorylation Disorders.
1. Invest Ophthalmol Vis Sci - published October 1, 2020
2. Oh JK, Lima de Carvalho JR Jr, Nuzbrokh Y, Ryu J, Chemudupati T, Mahajan VB, Sparrow JR, Tsang SH
SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
1. Nature - published October 1, 2020
2. Barnes CO, Jette CA, Abernathy ME, Dam KA, Esswein SR, Gristick HB, Malyutin AG, Sharaf NG, Huey-Tubman KE, Lee YE, Robbiani DF, Nussenzweig MC, West AP Jr, Bjorkman PJ
Mechanism of efficient double-strand break repair by a long non-coding RNA.
1. Nucleic Acids Res - published October 1, 2020
2. Thapar R, Wang JL, Hammel M, Ye R, Liang K, Sun C, Hnizda A, Liang S, Maw SS, Lee L, Villarreal H, Forrester I, Fang S, Tsai MS, Blundell TL, Davis AJ, Lin C, Lees-Miller SP, Strick TR, Tainer JA
The molecular structure of long non-coding RNAs: emerging patterns and functional implications.
1. Crit Rev Biochem Mol Biol - published October 1, 2020
2. Chillón I, Marcia M
Albumin-binding domain extends half-life of glucagon-like peptide-1.
1. Eur J Pharmacol - published October 1, 2020
2. Tan H, Su W, Zhang W, Zhang J, Sattler M, Zou P
Prion biology: implications for Alzheimer's disease therapeutics.
1. Lancet Neurol - published October 1, 2020
2. Condello C, DeGrado WF, Prusiner SB