Member Publications

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124 Member Publications for May 2021

Na_vigating the intricacies of cellular machinery.
1. J Biol Chem - published May 28, 2021
2. Nathan S, Gabelli SB
A Fluorescence-Based Assay to Determine PDZ-Ligand Binding Thermodynamics.
1. Methods Mol Biol - published May 20, 2021
2. Sun YJ, Fuentes EJ
Crystallographic Studies of PDZ Domain-Peptide Interactions of the Scribble Polarity Module.
1. Methods Mol Biol - published May 20, 2021
2. Maddumage JC, Stewart BZ, Humbert PO, Kvansakul M
Distinguishing Signal From Noise in Immunopeptidome Studies of Limiting-Abundance Biological Samples: Peptides Presented by I-A^b in C57BL/6 Mouse Thymus.
1. Front Immunol - published May 17, 2021
2. Nanaware PP, Jurewicz MM, Clement CC, Lu L, Santambrogio L, Stern LJ
Identification of recombinant Fabs for structural and functional characterization of HIV-host factor complexes.
1. PLoS One - published May 13, 2021
2. Sevillano N, Green EM, Votteler J, Kim DY, Ren X, Yang B, Liu X, Lourenço AL, Hurley JH, Farr-Jones S, Gross JD, Cheng Y, Craik CS
Beyond ribose and phosphate: Selected nucleic acid modifications for structure-function investigations and therapeutic applications.
1. Beilstein J Org Chem - published May 13, 2021
2. Liczner C, Duke K, Juneau G, Egli M, Wilds CJ
Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20.
1. EMBO Rep - published May 9, 2021
2. Stadler D, Kächele M, Jones AN, Hess J, Urban C, Schneider J, Xia Y, Oswald A, Nebioglu F, Bester R, Lasitschka F, Ringelhan M, Ko C, Chou WM, Geerlof A, van de Klundert MA, Wettengel JM, Schirmacher P, Heikenwälder M, Schreiner S, Bartenschlager R, Pichlmair A, Sattler M, Unger K, Protzer U
Modernized Uniform Representation of Carbohydrate Molecules in theProtein Data Bank.
1. Glycobiology - published May 8, 2021
2. Shao C, Feng Z, Westbrook JD, Peisach E, Berrisford J, Ikegawa Y, Kurisu G, Velankar S, Burley SK, Young JY
iPick: Multiprocessing software for integrated NMR signal detection and validation.
1. J Magn Reson - published May 7, 2021
2. Rahimi M, Lee Y, Markley JL, Lee W
Structural insights into the cross-neutralization of SARS-CoV and SARS-CoV-2 by the human monoclonal antibody 47D11.
1. Sci Adv - published May 6, 2021
2. Fedry J, Hurdiss DL, Wang C, Li W, Obal G, Drulyte I, Du W, Howes SC, van Kuppeveld FJM, Förster F, Bosch BJ
Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex.
1. Nat Commun - published May 6, 2021
2. Wang JY, Hoel CM, Al-Shayeb B, Banfield JF, Brohawn SG, Doudna JA
Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets.
1. Immunity - published May 6, 2021
2. Dugan HL, Stamper CT, Li L, Changrob S, Asby NW, Halfmann PJ, Zheng NY, Huang M, Shaw DG, Cobb MS, Erickson SA, Guthmiller JJ, Stovicek O, Wang J, Winkler ES, Madariaga ML, Shanmugarajah K, Jansen MO, Amanat F, Stewart I, Utset HA, Huang J, Nelson CA, Dai YN, Hall PD, Jedrzejczak RP, Joachimiak A, Krammer F, Diamond MS, Fremont DH, Kawaoka Y, Wilson PC
Protein and Small Molecule Structure Determination by the Cryo-EM Method MicroED.
1. Methods Mol Biol - published May 5, 2021
2. Danelius E, Gonen T
CM1-driven assembly and activation of yeast γ-tubulin small complex underlies microtubule nucleation.
1. Elife - published May 5, 2021
2. Brilot AF, Lyon AS, Zelter A, Viswanath S, Maxwell A, MacCoss MJ, Muller EG, Sali A, Davis TN, Agard DA
Structural Insights into the Respiratory Syncytial Virus RNA Synthesis Complexes.
1. Viruses - published May 5, 2021
2. Cao D, Gao Y, Liang B
Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo.
1. J Med Chem - published May 4, 2021
2. Halkina T, Henderson JL, Lin EY, Himmelbauer MK, Jones JH, Nevalainen M, Feng J, King K, Rooney M, Johnson JL, Marcotte DJ, Chodaparambil JV, Kumar PR, Patterson TA, Murugan P, Schuman E, Wong L, Hesson T, Lamore S, Bao C, Calhoun M, Certo H, Amaral B, Dillon GM, Gilfillan R, de Turiso FG
Sec17/Sec18 can support membrane fusion without help from completion of SNARE zippering.
1. Elife - published May 4, 2021
2. Song H, Torng TL, Orr AS, Brunger AT, Wickner WT
COVID-19 serological survey using micro blood sampling.
1. Sci Rep - published May 4, 2021
2. Matthews MM, Kim TG, Shibata S, Shibata N, Butcher C, Hyun J, Kim KY, Robb T, Jheng SS, Narita M, Mori T, Collins M, Wolf M
Broad and potently neutralizing monoclonal antibodies isolated from human survivors of New World hantavirus infection.
1. Cell Rep - published May 4, 2021
2. Engdahl TB, Kuzmina NA, Ronk AJ, Mire CE, Hyde MA, Kose N, Josleyn MD, Sutton RE, Mehta A, Wolters RM, Lloyd NM, Valdivieso FR, Ksiazek TG, Hooper JW, Bukreyev A, Crowe JE Jr
A pooled case-only analysis of reproductive risk factors and breast cancer subtype among black women in the Southeastern United States.
1. Cancer Epidemiol Biomarkers Prev - published May 4, 2021
2. Sanderson M, Pal T, Beeghly-Fadiel A, Fadden MK, Dujon SA, Clinton C, Jimenez C, Davis J, Fortune M, Thompson J, Benson K, Conley N, Reid S, Tezak A, Shu XO, Zheng W, Blot WJ, Lipworth L
Familial Autonomic Ganglionopathy Caused by Rare CHRNA3 Genetic Variants.
1. Neurology - published May 4, 2021
2. Shibao C, Joos K, Phillips JA 3rd, Cogan J, Newman JH, Hamid R, Meiler J, Capra J, Sheehan J, Vetrini F, Yang Y, Black B, Diedrich A, Roberston D, Biaggioni I
Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes.
1. Science - published May 4, 2021
2. Voss WN, Hou YJ, Johnson NV, Delidakis G, Kim JE, Javanmardi K, Horton AP, Bartzoka F, Paresi CJ, Tanno Y, Chou CW, Abbasi SA, Pickens W, George K, Boutz DR, Towers DM, McDaniel JR, Billick D, Goike J, Rowe L, Batra D, Pohl J, Lee J, Gangappa S, Sambhara S, Gadush M, Wang N, Person MD, Iverson BL, Gollihar JD, Dye J, Herbert A, Finkelstein IJ, Baric RS, McLellan JS, Georgiou G, Lavinder JJ, Ippolito GC
Gold nanoparticles and tilt pairs to assess protein flexibility by cryo-electron microscopy.
1. Ultramicroscopy - published May 4, 2021
2. Jagota M, Townshend RJL, Kang LW, Bushnell DA, Dror RO, Kornberg RD, Azubel M
Microtubules form by progressively faster tubulin accretion, not by nucleation-elongation.
1. J Cell Biol - published May 3, 2021
2. Rice LM, Moritz M, Agard DA
Broadly neutralizing monoclonal antibodies protect against multiple tick-borne flaviviruses.
1. J Exp Med - published May 3, 2021
2. VanBlargan LA, Errico JM, Kafai NM, Burgomaster KE, Jethva PN, Broeckel RM, Meade-White K, Nelson CA, Himansu S, Wang D, Handley SA, Gross ML, Best SM, Pierson TC, Fremont DH, Diamond MS
Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease.
1. J Exp Med - published May 3, 2021
2. Agudelo M, Palus M, Keeffe JR, Bianchini F, Svoboda P, Salát J, Peace A, Gazumyan A, Cipolla M, Kapoor T, Guidetti F, Yao KH, Elsterová J, Teislerová D, Chrdle A, Hönig V, Oliveira T, West AP, Lee YE, Rice CM, MacDonald MR, Bjorkman PJ, Růžek D, Robbiani DF, Nussenzweig MC
An arginine residue in the outer segment of hASIC1a TM1 affects both proton affinity and channel desensitization.
1. J Gen Physiol - published May 3, 2021
2. Chen Z, Kuenze G, Meiler J, Canessa CM
Toward Understanding the Molecular Role of SNX27/Retromer in Human Health and Disease.
1. Front Cell Dev Biol - published May 3, 2021
2. Chandra M, Kendall AK, Jackson LP
Membrane Interactions of the Peroxisomal Proteins PEX5 and PEX14.
1. Front Cell Dev Biol - published May 3, 2021
2. Gaussmann S, Gopalswamy M, Eberhardt M, Reuter M, Zou P, Schliebs W, Erdmann R, Sattler M
Autism-associated vigilin depletion impairs DNA damage repair.
1. Mol Cell Biol - published May 3, 2021
2. Banday S, Pandita RK, Mushtaq A, Bacolla A, Mir US, Singh DK, Jan S, Bhat KP, Hunt CR, Rao G, Charaka VK, Tainer JA, Pandita TK, Altaf M
Evolution of delayed resistance to immunotherapy in a melanoma responder.
1. Nat Med - published May 3, 2021
2. Liu D, Lin JR, Robitschek EJ, Kasumova GG, Heyde A, Shi A, Kraya A, Zhang G, Moll T, Frederick DT, Chen YA, Wang S, Schapiro D, Ho LL, Bi K, Sahu A, Mei S, Miao B, Sharova T, Alvarez-Breckenridge C, Stocking JH, Kim T, Fadden R, Lawrence D, Hoang MP, Cahill DP, Malehmir M, Nowak MA, Brastianos PK, Lian CG, Ruppin E, Izar B, Herlyn M, Van Allen EM, Nathanson K, Flaherty KT, Sullivan RJ, Kellis M, Sorger PK, Boland GM
How structural biology transformed studies of transcription regulation.
1. J Biol Chem - published May 3, 2021
2. Wolberger C
Architecture and assembly dynamics of the essential mitochondrial chaperone complex TIM9·10·12.
1. Structure - published May 3, 2021
2. Weinhäupl K, Wang Y, Hessel A, Brennich M, Lindorff-Larsen K, Schanda P
X-ray scattering reveals disordered linkers and dynamic interfaces in complexes and mechanisms for DNA double-strand break repair impacting cell and cancer biology.
1. Protein Sci - published May 3, 2021
2. Hammel M, Tainer JA
Development of selective bispecific Wnt mimetics for bone loss and repair.
1. Nat Commun - published May 3, 2021
2. Fowler TW, Mitchell TL, Janda CY, Xie L, Tu S, Chen H, Zhang H, Ye J, Ouyang B, Yuan TZ, Lee SJ, Newman M, Tripuraneni N, Rego ES, Mutha D, Dilip A, Vuppalapaty M, Baribault H, Yeh WC, Li Y
Ephrin-A1 and the sheddase ADAM12 are upregulated in COVID-19.
1. Heliyon - published May 3, 2021
2. Mendoza R, Saha N, Momeni A, Gabutan E, Alawad M, Dehghani A, Diks J, Lin B, Wang D, Alshal M, Fyke W, Wang B, Himanen JP, Premsrirut P, Nikolov DB
Dynamic remodeling of host membranes by self-organizing bacterial effectors.
1. Science - published May 2, 2021
2. Hsieh TS, Lopez VA, Black MH, Osinski A, Pawłowski K, Tomchick DR, Liou J, Tagliabracci VS
A cellular and spatial map of the choroid plexus across brain ventricles and ages.
1. Cell - published May 2, 2021
2. Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK
Structural studies of the shortest extended synaptotagmin with only two C2 domains from Trypanosoma brucei.
1. iScience - published May 2, 2021
2. Stepinac E, Landrein N, Skwarzyńska D, Wójcik P, Lesigang J, Lučić I, He CY, Bonhivers M, Robinson DR, Dong G
The SHREAD gene therapy platform for paracrine delivery improves tumor localization and intratumoral effects of a clinical antibody.
1. Proc Natl Acad Sci U S A - published May 2, 2021
2. Smith SN, Schubert R, Simic B, Brücher D, Schmid M, Kirk N, Freitag PC, Gradinaru V, Plückthun A
Pharmacological inhibition of PI5P4Kα/β disrupts cell energy metabolism and selectively kills p53-null tumor cells.
1. Proc Natl Acad Sci U S A - published May 2, 2021
2. Chen S, Chandra Tjin C, Gao X, Xue Y, Jiao H, Zhang R, Wu M, He Z, Ellman J, Ha Y
Structural basis of TRAPPIII-mediated Rab1 activation.
1. EMBO J - published May 2, 2021
2. Joiner AM, Phillips BP, Yugandhar K, Sanford EJ, Smolka MB, Yu H, Miller EA, Fromme JC
Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue.
1. Nat Commun - published May 2, 2021
2. Georgiadi A, Lopez-Salazar V, Merahbi RE, Karikari RA, Ma X, Mourão A, Klepac K, Bühler L, Alfaro AJ, Kaczmarek I, Linford A, Bosma M, Shilkova O, Ritvos O, Nakamura N, Hirose S, Lassi M, Teperino R, Machado J, Scheideler M, Dietrich A, Geerlof A, Feuchtinger A, Blutke A, Fischer K, Müller TD, Kessler K, Schöneberg T, Thor D, Hornemann S, Kruse M, Nawroth P, Pivovarova-Ramich O, Pfeiffer AFH, Sattler M, Blüher M, Herzig S
Chemical-genetic interrogation of RNA polymerase mutants reveals structure-function relationships and physiological tradeoffs.
1. Mol Cell - published May 2, 2021
2. Shiver AL, Osadnik H, Peters JM, Mooney RA, Wu PI, Henry KK, Braberg H, Krogan NJ, Hu JC, Landick R, Huang KC, Gross CA
Self-association of MreC as a regulatory signal in bacterial cell wall elongation.
1. Nat Commun - published May 2, 2021
2. Martins A, Contreras-Martel C, Janet-Maitre M, Miyachiro MM, Estrozi LF, Trindade DM, Malospirito CC, Rodrigues-Costa F, Imbert L, Job V, Schoehn G, Attrée I, Dessen A
Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer.
1. Mol Cancer Res - published May 2, 2021
2. Mayne CG, Toy W, Carlson KE, Bhatt T, Fanning SW, Greene GL, Katzenellenbogen BS, Chandarlapaty S, Katzenellenbogen JA, Tajkhorshid E
Alum:CpG adjuvant enables SARS-CoV-2 RBD-induced protection in aged mice and synergistic activation of human elder type 1 immunity.
1. bioRxiv - published May 2, 2021
2. Nanishi E, Borriello F, O'Meara TR, McGrath ME, Saito Y, Haupt RE, Seo HS, van Haren SD, Brook B, Chen J, Diray-Arce J, Doss-Gollin S, Leon M, Chew K, Menon M, Song K, Xu AZ, Caradonna TM, Feldman J, Hauser BM, Schmidt AG, Sherman AC, Baden LR, Ernst RK, Dillen C, Weston SM, Johnson RM, Hammond HL, Mayer R, Burke A, Bottazzi ME, Hotez PJ, Strych U, Chang A, Yu J, Barouch DH, Dhe-Paganon S, Zanoni I, Ozonoff A, Frieman MB, Levy O, Dowling DJ
PKC-phosphorylation of Liprin-α3 triggers phase separation and controls presynaptic active zone structure.
1. Nat Commun - published May 2, 2021
2. Emperador-Melero J, Wong MY, Wang SSH, de Nola G, Nyitrai H, Kirchhausen T, Kaeser PS
Kinetics of the multitasking high-affinity Win binding site of WDR5 in restricted and unrestricted conditions.
1. Biochem J - published May 2, 2021
2. Imran A, Moyer BS, Canning AJ, Kalina D, Duncan TM, Moody KJ, Wolfe AJ, Cosgrove MS, Movileanu L
[Effectiveness of abdominal minimal incision sacrocolpopexy for advanced pelvic organ prolapse].
1. Zhonghua Fu Chan Ke Za Zhi - published May 2, 2021
2. Shen WJ, Lu YX, Liu X, Liu JX, Zhang YH, Zhao Y, Niu K, Wang WY, Wang QY, Schaffer SCHAFFER
The molecular coupling between substrate recognition and ATP turnover in a AAA+ hexameric helicase loader.
1. Elife - published May 2, 2021
2. Puri N, Fernandez AJ, O'Shea Murray VL, McMillan S, Keck JL, Berger JM
Mechanistic dissection of increased enzymatic rate in a phase-separated compartment.
1. Nat Chem Biol - published May 2, 2021
2. Peeples W, Rosen MK
Acute pharmacological degradation of Helios destabilizes regulatory T cells.
1. Nat Chem Biol - published May 2, 2021
2. Wang ES, Verano AL, Nowak RP, Yuan JC, Donovan KA, Eleuteri NA, Yue H, Ngo KH, Lizotte PH, Gokhale PC, Gray NS, Fischer ES
Familial hypereosinophilia associated with eosinophilic gastrointestinal symptoms in individuals with a missense mutation in CKLF-like MARVEL transmembrane domain containing 3 (CMTM3).
1. Clin Exp Allergy - published May 2, 2021
2. Wardlaw AJ, Barwell J, Hitchman C, Shrine N, Bennett N, Adewoye AB, Ozturk H, Ntereke T, Wurm P, Tobin MD, Gooptu B, Hollox EJ, Wain LV
Potent Cyclic Peptide Inhibitors of FXIIa Discovered by mRNA Display with Genetic Code Reprogramming.
1. J Med Chem - published May 2, 2021
2. Ford DJ, Duggan NM, Fry SE, Ripoll-Rozada J, Agten SM, Liu W, Corcilius L, Hackeng TM, van Oerle R, Spronk HMH, Ashhurst AS, Mini Sasi V, Kaczmarski JA, Jackson CJ, Pereira PJB, Passioura T, Suga H, Payne RJ
Enterocytes, fibroblasts and myeloid cells synergize in anti-bacterial and anti-viral pathways with IL22 as the central cytokine.
1. Commun Biol - published May 2, 2021
2. Klooster JPT, Bol-Schoenmakers M, van Summeren K, van Vliet ALW, de Haan CAM, van Kuppeveld FJM, Verkoeijen S, Pieters R
Dan Salah Tawfik (1955-2021)-A giant of protein evolution.
1. EMBO Rep - published May 2, 2021
2. Elias MH, Fraser JS, Kamerlin SCL, Patrick WM, Jackson CJ
Crystal Structure of the [FeFe]-Hydrogenase Maturase HydE Bound to Complex-B.
1. J Am Chem Soc - published May 2, 2021
2. Rohac R, Martin L, Liu L, Basu D, Tao L, Britt RD, Rauchfuss TB, Nicolet Y
Atomistic basis of force generation, translocation, and coordination in a viral genome packaging motor.
1. Nucleic Acids Res - published May 2, 2021
2. Pajak J, Dill E, Reyes-Aldrete E, White MA, Kelch BA, Jardine PJ, Arya G, Morais MC
Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
1. Nat Commun - published May 2, 2021
2. Obr M, Ricana CL, Nikulin N, Feathers JR, Klanschnig M, Thader A, Johnson MC, Vogt VM, Schur FKM, Dick RA
Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions.
1. Cell Rep Med - published May 2, 2021
2. Shiakolas AR, Kramer KJ, Wrapp D, Richardson SI, Schäfer A, Wall S, Wang N, Janowska K, Pilewski KA, Venkat R, Parks R, Manamela NP, Raju N, Fechter EF, Holt CM, Suryadevara N, Chen RE, Martinez DR, Nargi RS, Sutton RE, Ledgerwood JE, Graham BS, Diamond MS, Haynes BF, Acharya P, Carnahan RH, Crowe JE Jr, Baric RS, Morris L, McLellan JS, Georgiev IS
Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever.
1. Cell - published May 2, 2021
2. Fels JM, Maurer DP, Herbert AS, Wirchnianski AS, Vergnolle O, Cross RW, Abelson DM, Moyer CL, Mishra AK, Aguilan JT, Kuehne AI, Pauli NT, Bakken RR, Nyakatura EK, Hellert J, Quevedo G, Lobel L, Balinandi S, Lutwama JJ, Zeitlin L, Geisbert TW, Rey FA, Sidoli S, McLellan JS, Lai JR, Bornholdt ZA, Dye JM, Walker LM, Chandran K
Cryo-EM and Single-Particle Analysis with Scipion.
1. J Vis Exp - published May 2, 2021
2. Jiménez-Moreno A, Del Caño L, Martínez M, Ramírez-Aportela E, Cuervo A, Melero R, Sánchez-García R, Strelak D, Fernández-Giménez E, de Isidro-Gómez FP, Herreros D, Conesa P, Fonseca Y, Maluenda D, Jiménez de la Morena J, Macías JR, Losana P, Marabini R, Carazo JM, Sorzano COS
Advances in the Treatment of Chronic Pain by Targeting GPCRs.
1. Biochemistry - published May 1, 2021
2. Che T
Predicted Mode of Binding to and Allosteric Modulation of the μ-Opioid Receptor by Kratom's Alkaloids with Reported Antinociception In Vivo.
1. Biochemistry - published May 1, 2021
2. Zhou Y, Ramsey S, Provasi D, El Daibani A, Appourchaux K, Chakraborty S, Kapoor A, Che T, Majumdar S, Filizola M
Kinetic and structural analysis of the inactivation of urease by mixed-ligand phosphine halide Ag(I) complexes.
1. J Inorg Biochem - published May 1, 2021
2. Mazzei L, Cirri D, Cianci M, Messori L, Ciurli S
Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex.
1. Proc Natl Acad Sci U S A - published May 1, 2021
2. Malone B, Chen J, Wang Q, Llewellyn E, Choi YJ, Olinares PDB, Cao X, Hernandez C, Eng ET, Chait BT, Shaw DE, Landick R, Darst SA, Campbell EA
Errors in the deposited SFTSV L protein structure.
1. Nat Microbiol - published May 1, 2021
2. Cusack S, Rosenthal M
Integrative analysis reveals unique structural and functional features of the Smc5/6 complex.
1. Proc Natl Acad Sci U S A - published May 1, 2021
2. Yu Y, Li S, Ser Z, Sanyal T, Choi K, Wan B, Kuang H, Sali A, Kentsis A, Patel DJ, Zhao X
Optimized cryo-EM data-acquisition workflow by sample-thickness determination.
1. Acta Crystallogr D Struct Biol - published May 1, 2021
2. Rheinberger J, Oostergetel G, Resch GP, Paulino C
Challenges in solving structures from radiation-damaged tomograms of protein nanocrystals assessed by simulation.
1. Acta Crystallogr D Struct Biol - published May 1, 2021
2. Peck A, Yao Q, Brewster AS, Zwart PH, Heumann JM, Sauter NK, Jensen GJ
Structural biology in the time of COVID-19: perspectives on methods and milestones.
1. IUCrJ - published May 1, 2021
2. Lynch ML, Snell EH, Bowman SEJ
Cryo-EM structure of a thermostable bacterial nanocompartment.
1. IUCrJ - published May 1, 2021
2. Wiryaman T, Toor N
A viral genome packaging motor transitions between cyclic and helical symmetry to translocate dsDNA.
1. Sci Adv - published May 1, 2021
2. Woodson M, Pajak J, Mahler BP, Zhao W, Zhang W, Arya G, White MA, Jardine PJ, Morais MC
50 years of PBD: a catalyst in structural biology.
1. Nat Methods - published May 1, 2021
2. Bonvin AMJJ
Making Choices: DNA Replication Fork Recovery Mechanisms.
1. Semin Cell Dev Biol - published May 1, 2021
2. Kondratick CM, Washington MT, Spies M
Beginning at the End(s): A Latent End-Binding Network at the Host-Pathogen Interface.
1. Biochemistry - published May 1, 2021
2. Ravalin M, Craik CS
Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses.
1. Nature - published May 1, 2021
2. Saunders KO, Lee E, Parks R, Martinez DR, Li D, Chen H, Edwards RJ, Gobeil S, Barr M, Mansouri K, Alam SM, Sutherland LL, Cai F, Sanzone AM, Berry M, Manne K, Bock KW, Minai M, Nagata BM, Kapingidza AB, Azoitei M, Tse LV, Scobey TD, Spreng RL, Rountree RW, DeMarco CT, Denny TN, Woods CW, Petzold EW, Tang J, Oguin TH 3rd, Sempowski GD, Gagne M, Douek DC, Tomai MA, Fox CB, Seder R, Wiehe K, Weissman D, Pardi N, Golding H, Khurana S, Acharya P, Andersen H, Lewis MG, Moore IN, Montefiori DC, Baric RS, Haynes BF
The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains.
1. Elife - published May 1, 2021
2. Zhemkov V, Ditlev JA, Lee WR, Wilson M, Liou J, Rosen MK, Bezprozvanny I
Making the invisible enemy visible.
1. Nat Struct Mol Biol - published May 1, 2021
2. Croll TI, Diederichs K, Fischer F, Fyfe CD, Gao Y, Horrell S, Joseph AP, Kandler L, Kippes O, Kirsten F, Müller K, Nolte K, Payne AM, Reeves M, Richardson JS, Santoni G, Stäb S, Tronrud DE, von Soosten LC, Williams CJ, Thorn A
Constructing ion channels from water-soluble α-helical barrels.
1. Nat Chem - published May 1, 2021
2. Scott AJ, Niitsu A, Kratochvil HT, Lang EJM, Sengel JT, Dawson WM, Mahendran KR, Mravic M, Thomson AR, Brady RL, Liu L, Mulholland AJ, Bayley H, DeGrado WF, Wallace MI, Woolfson DN
Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo.
1. Nat Chem Biol - published May 1, 2021
2. Dubiella C, Pinch BJ, Koikawa K, Zaidman D, Poon E, Manz TD, Nabet B, He S, Resnick E, Rogel A, Langer EM, Daniel CJ, Seo HS, Chen Y, Adelmant G, Sharifzadeh S, Ficarro SB, Jamin Y, Martins da Costa B, Zimmerman MW, Lian X, Kibe S, Kozono S, Doctor ZM, Browne CM, Yang A, Stoler-Barak L, Shah RB, Vangos NE, Geffken EA, Oren R, Koide E, Sidi S, Shulman Z, Wang C, Marto JA, Dhe-Paganon S, Look T, Zhou XZ, Lu KP, Sears RC, Chesler L, Gray NS, London N
Synthesis of fluorinated aminoalkylboronic acids from amphoteric α-boryl aldehydes.
1. Angew Chem Int Ed Engl - published May 1, 2021
2. Soor HS, Diaz DB, Burton KI, Yudin AK
Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity.
1. Nat Commun - published May 1, 2021
2. Zhou H, Lu J, Chinnaswamy K, Stuckey JA, Liu L, McEachern D, Yang CY, Bernard D, Shen H, Rui L, Sun Y, Wang S
Analysis of the Evolution of Pandemic Influenza A(H1N1) Virus Neuraminidase Reveals Entanglement of Different Phenotypic Characteristics.
1. mBio - published May 1, 2021
2. Dai M, Du W, Martínez-Romero C, Leenders T, Wennekes T, Rimmelzwaan GF, van Kuppeveld FJM, Fouchier RAM, Garcia-Sastre A, de Vries E, de Haan CAM
Lasofoxifene as a potential treatment for therapy-resistant ER-positive metastatic breast cancer.
1. Breast Cancer Res - published May 1, 2021
2. Lainé M, Fanning SW, Chang YF, Green B, Greene ME, Komm B, Kurleto JD, Phung L, Greene GL
Immunogenicity of COVID-19 mRNA Vaccines in Pregnant and Lactating Women.
1. JAMA - published May 1, 2021
2. Collier AY, McMahan K, Yu J, Tostanoski LH, Aguayo R, Ansel J, Chandrashekar A, Patel S, Apraku Bondzie E, Sellers D, Barrett J, Sanborn O, Wan H, Chang A, Anioke T, Nkolola J, Bradshaw C, Jacob-Dolan C, Feldman J, Gebre M, Borducchi EN, Liu J, Schmidt AG, Suscovich T, Linde C, Alter G, Hacker MR, Barouch DH
Characterization of the multidrug efflux transporter styMdtMfrom Salmonella enterica serovar Typhi.
1. Proteins - published May 1, 2021
2. Shaheen A, Ismat F, Iqbal M, Haque A, Ul-Haq Z, Mirza O, De Zorzi R, Walz T, Rahman M
Inclusion of the C-Terminal Domain in the β-Sheet Core of Heparin-Fibrillized Three-Repeat Tau Protein Revealed by Solid-State Nuclear Magnetic Resonance Spectroscopy.
1. J Am Chem Soc - published May 1, 2021
2. Dregni AJ, Wang HK, Wu H, Duan P, Jin J, DeGrado WF, Hong M
Practical considerations for using K3 cameras in CDS mode for high-resolution and high-throughput single particle cryo-EM.
1. J Struct Biol - published May 1, 2021
2. Sun M, Azumaya C, Tse E, Frost A, Southworth D, Verba KA, Cheng Y, Agard DA
Bipartite binding of the N terminus of Skp2 to cyclin A.
1. Structure - published May 1, 2021
2. Kelso S, Orlicky S, Beenstock J, Ceccarelli DF, Kurinov I, Gish G, Sicheri F
Protein-based antigen presentation platforms for nanoparticle vaccines.
1. NPJ Vaccines - published May 1, 2021
2. Nguyen B, Tolia NH
Investigate the origins of COVID-19.
1. Science - published May 1, 2021
2. Bloom JD, Chan YA, Baric RS, Bjorkman PJ, Cobey S, Deverman BE, Fisman DN, Gupta R, Iwasaki A, Lipsitch M, Medzhitov R, Neher RA, Nielsen R, Patterson N, Stearns T, van Nimwegen E, Worobey M, Relman DA
Mannose and mannobiose specific responses of insect associated cellulolytic Streptomyces.
1. Appl Environ Microbiol - published May 1, 2021
2. Ohashi K, Hataya S, Nakata A, Matsumoto K, Kato N, Sato W, Carlos-Shanley C, Beebe ET, Currie CR, Fox BG, Takasuka TE
Structure-guided design of ultrapotent disruptive IgE inhibitors to rapidly terminate acute allergic reactions.
1. J Allergy Clin Immunol - published May 1, 2021
2. Pennington LF, Gasser P, Brigger D, Guntern P, Eggel A, Jardetzky TS
A knowledge-based, structural-aided discovery of a novel class of 2-phenylimidazo[1,2-a]pyridine-6-carboxamide H-PGDS inhibitors.
1. Bioorg Med Chem Lett - published May 1, 2021
2. Deaton DN, Diaz E, Do Y, Gampe RT, Guss JH, Hancock AP, Hobbs H, Hodgson ST, Holt J, Jeune MR, Kahler KM, Kramer HF, Le J, Mortenson PN, Musetti C, Nolte RT, Orband-Miller LA, Peckham GE, Petrov KG, Pietrak BL, Poole C, Price DJ, Saxty G, Schulte CA, Shillings A, Smalley TL Jr, Somers DO, Stewart EL, Stuart JD, Thomson SA
Q493K and Q498H substitutions in Spike promote adaptation of SARS-CoV-2 in mice.
1. EBioMedicine - published May 1, 2021
2. Huang K, Zhang Y, Hui X, Zhao Y, Gong W, Wang T, Zhang S, Yang Y, Deng F, Zhang Q, Chen X, Yang Y, Sun X, Chen H, Tao YJ, Zou Z, Jin M
Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells.
1. Cell Rep - published May 1, 2021
2. Parker R, Partridge T, Wormald C, Kawahara R, Stalls V, Aggelakopoulou M, Parker J, Powell Doherty R, Ariosa Morejon Y, Lee E, Saunders K, Haynes BF, Acharya P, Thaysen-Andersen M, Borrow P, Ternette N
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
1. Nat Genet - published May 1, 2021
2. Mullins N, Forstner AJ, O'Connell KS, Coombes B, Coleman JRI, Qiao Z, Als TD, Bigdeli TB, Børte S, Bryois J, Charney AW, Drange OK, Gandal MJ, Hagenaars SP, Ikeda M, Kamitaki N, Kim M, Krebs K, Panagiotaropoulou G, Schilder BM, Sloofman LG, Steinberg S, Trubetskoy V, Winsvold BS, Won HH, Abramova L, Adorjan K, Agerbo E, Al Eissa M, Albani D, Alliey-Rodriguez N, Anjorin A, Antilla V, Antoniou A, Awasthi S, Baek JH, Bækvad-Hansen M, Bass N, Bauer M, Beins EC, Bergen SE, Birner A, Bøcker Pedersen C, Bøen E, Boks MP, Bosch R, Brum M, Brumpton BM, Brunkhorst-Kanaan N, Budde M, Bybjerg-Grauholm J, Byerley W, Cairns M, Casas M, Cervantes P, Clarke TK, Cruceanu C, Cuellar-Barboza A, Cunningham J, Curtis D, Czerski PM, Dale AM, Dalkner N, David FS, Degenhardt F, Djurovic S, Dobbyn AL, Douzenis A, Elvsåshagen T, Escott-Price V, Ferrier IN, Fiorentino A, Foroud TM, Forty L, Frank J, Frei O, Freimer NB, Frisén L, Gade K, Garnham J, Gelernter J, Giørtz Pedersen M, Gizer IR, Gordon SD, Gordon-Smith K, Greenwood TA, Grove J, Guzman-Parra J, Ha K, Haraldsson M, Hautzinger M, Heilbronner U, Hellgren D, Herms S, Hoffmann P, Holmans PA, Huckins L, Jamain S, Johnson JS, Kalman JL, Kamatani Y, Kennedy JL, Kittel-Schneider S, Knowles JA, Kogevinas M, Koromina M, Kranz TM, Kranzler HR, Kubo M, Kupka R, Kushner SA, Lavebratt C, Lawrence J, Leber M, Lee HJ, Lee PH, Levy SE, Lewis C, Liao C, Lucae S, Lundberg M, MacIntyre DJ, Magnusson SH, Maier W, Maihofer A, Malaspina D, Maratou E, Martinsson L, Mattheisen M, McCarroll SA, McGregor NW, McGuffin P, McKay JD, Medeiros H, Medland SE, Millischer V, Montgomery GW, Moran JL, Morris DW, Mühleisen TW, O'Brien N, O'Donovan C, Olde Loohuis LM, Oruc L, Papiol S, Pardiñas AF, Perry A, Pfennig A, Porichi E, Potash JB, Quested D, Raj T, Rapaport MH, DePaulo JR, Regeer EJ, Rice JP, Rivas F, Rivera M, Roth J, Roussos P, Ruderfer DM, Sánchez-Mora C, Schulte EC, Senner F, Sharp S, Shilling PD, Sigurdsson E, Sirignano L, Slaney C, Smeland OB, Smith DJ, Sobell JL, Søholm Hansen C, Soler Artigas M, Spijker AT, Stein DJ, Strauss JS, Świątkowska B, Terao C, Thorgeirsson TE, Toma C, Tooney P, Tsermpini EE, Vawter MP, Vedder H, Walters JTR, Witt SH, Xi S, Xu W, Yang JMK, Young AH, Young H, Zandi PP, Zhou H, Zillich L, HUNT All-In Psychiatry., Adolfsson R, Agartz I, Alda M, Alfredsson L, Babadjanova G, Backlund L, Baune BT, Bellivier F, Bengesser S, Berrettini WH, Blackwood DHR, Boehnke M, Børglum AD, Breen G, Carr VJ, Catts S, Corvin A, Craddock N, Dannlowski U, Dikeos D, Esko T, Etain B, Ferentinos P, Frye M, Fullerton JM, Gawlik M, Gershon ES, Goes FS, Green MJ, Grigoroiu-Serbanescu M, Hauser J, Henskens F, Hillert J, Hong KS, Hougaard DM, Hultman CM, Hveem K, Iwata N, Jablensky AV, Jones I, Jones LA, Kahn RS, Kelsoe JR, Kirov G, Landén M, Leboyer M, Lewis CM, Li QS, Lissowska J, Lochner C, Loughland C, Martin NG, Mathews CA, Mayoral F, McElroy SL, McIntosh AM, McMahon FJ, Melle I, Michie P, Milani L, Mitchell PB, Morken G, Mors O, Mortensen PB, Mowry B, Müller-Myhsok B, Myers RM, Neale BM, Nievergelt CM, Nordentoft M, Nöthen MM, O'Donovan MC, Oedegaard KJ, Olsson T, Owen MJ, Paciga SA, Pantelis C, Pato C, Pato MT, Patrinos GP, Perlis RH, Posthuma D, Ramos-Quiroga JA, Reif A, Reininghaus EZ, Ribasés M, Rietschel M, Ripke S, Rouleau GA, Saito T, Schall U, Schalling M, Schofield PR, Schulze TG, Scott LJ, Scott RJ, Serretti A, Shannon Weickert C, Smoller JW, Stefansson H, Stefansson K, Stordal E, Streit F, Sullivan PF, Turecki G, Vaaler AE, Vieta E, Vincent JB, Waldman ID, Weickert TW, Werge T, Wray NR, Zwart JA, Biernacka JM, Nurnberger JI, Cichon S, Edenberg HJ, Stahl EA, McQuillin A, Di Florio A, Ophoff RA, Andreassen OA
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
1. Elife - published May 1, 2021
2. Glassman CR, Su L, Majri-Morrison SS, Winkelmann H, Mo F, Li P, Pérez-Cruz M, Ho PP, Koliesnik I, Nagy N, Hnizdilova T, Picton LK, Kovar M, Bollyky P, Steinman L, Meyer E, Piehler J, Leonard WJ, Garcia KC
Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia.
1. Elife - published May 1, 2021
2. Aguilar JI, Cheng MH, Font J, Schwartz AC, Ledwitch K, Duran A, Mabry SJ, Belovich AN, Zhu Y, Carter AM, Shi L, Kurian MA, Fenollar-Ferrer C, Meiler J, Ryan RM, Mchaourab HS, Bahar I, Matthies HJ, Galli A
The histone H3K9M mutation synergizes with H3K14 ubiquitylation to selectively sequester histone H3K9 methyltransferase Clr4 at heterochromatin.
1. Cell Rep - published May 1, 2021
2. Shan CM, Kim JK, Wang J, Bao K, Sun Y, Chen H, Yue JX, Stirpe A, Zhang Z, Lu C, Schalch T, Liti G, Nagy PL, Tong L, Qiao F, Jia S
Heh2/Man1 may be an evolutionarily conserved sensor of NPC assembly state.
1. Mol Biol Cell - published May 1, 2021
2. Borah S, Thaller DJ, Hakhverdyan Z, Rodriguez EC, Isenhour AW, Rout MP, King MC, Lusk CP
A structural perspective on targeting the RTK/Ras/MAP kinase pathway in cancer.
1. Protein Sci - published May 1, 2021
2. Heppner DE, Eck MJ
Visualization of Platelet Integrins via Two-Photon Microscopy Using Anti-transmembrane Domain Peptides Containing a Blue Fluorescent Amino Acid.
1. Biochemistry - published May 1, 2021
2. Fong KP, Ahmed IA, Mravic M, Jo H, Kim OV, Litvinov RI, Weisel JW, DeGrado WF, Gai F, Bennett JS
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
1. J Med Chem - published May 1, 2021
2. Kryštůfek R, Šácha P, Starková J, Brynda J, Hradilek M, Tloušt'ová E, Grzymska J, Rut W, Boucher MJ, Drąg M, Majer P, Hájek M, Řezáčová P, Madhani HD, Craik CS, Konvalinka J
JunB is a key regulator of multiple myeloma bone marrow angiogenesis.
1. Leukemia - published May 1, 2021
2. Fan F, Malvestiti S, Vallet S, Lind J, Garcia-Manteiga JM, Morelli E, Jiang Q, Seckinger A, Hose D, Goldschmidt H, Stadlbauer A, Sun C, Mei H, Pecherstorfer M, Bakiri L, Wagner EF, Tonon G, Sattler M, Hu Y, Tassone P, Jaeger D, Podar K
Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding.
1. Nat Commun - published May 1, 2021
2. Wang K, Dagil R, Lavstsen T, Misra SK, Spliid CB, Wang Y, Gustavsson T, Sandoval DR, Vidal-Calvo EE, Choudhary S, Agerbaek MØ, Lindorff-Larsen K, Nielsen MA, Theander TG, Sharp JS, Clausen TM, Gourdon P, Salanti A
DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist.
1. PLoS Pathog - published May 1, 2021
2. Thépaut M, Luczkowiak J, Vivès C, Labiod N, Bally I, Lasala F, Grimoire Y, Fenel D, Sattin S, Thielens N, Schoehn G, Bernardi A, Delgado R, Fieschi F
TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis.
1. Cell Metab - published May 1, 2021
2. Huang D, Xu B, Liu L, Wu L, Zhu Y, Ghanbarpour A, Wang Y, Chen FJ, Lyu J, Hu Y, Kang Y, Zhou W, Wang X, Ding W, Li X, Jiang Z, Chen J, Zhang X, Zhou H, Li JZ, Guo C, Zheng W, Zhang X, Li P, Melia T, Reinisch K, Chen XW
Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin.
1. Nat Commun - published May 1, 2021
2. Lee YT, Ayoub A, Park SH, Sha L, Xu J, Mao F, Zheng W, Zhang Y, Cho US, Dou Y
In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels.
1. Nat Biotechnol - published May 1, 2021
2. Rothgangl T, Dennis MK, Lin PJC, Oka R, Witzigmann D, Villiger L, Qi W, Hruzova M, Kissling L, Lenggenhager D, Borrelli C, Egli S, Frey N, Bakker N, Walker JA 2nd, Kadina AP, Victorov DV, Pacesa M, Kreutzer S, Kontarakis Z, Moor A, Jinek M, Weissman D, Stoffel M, van Boxtel R, Holden K, Pardi N, Thöny B, Häberle J, Tam YK, Semple SC, Schwank G
Multivalent nanoparticle-based vaccines protect hamsters against SARS-CoV-2 after a single immunization.
1. Commun Biol - published May 1, 2021
2. Chiba S, Frey SJ, Halfmann PJ, Kuroda M, Maemura T, Yang JE, Wright ER, Kawaoka Y, Kane RS
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
1. Cell - published May 1, 2021
2. Williams WB, Meyerhoff RR, Edwards RJ, Li H, Manne K, Nicely NI, Henderson R, Zhou Y, Janowska K, Mansouri K, Gobeil S, Evangelous T, Hora B, Berry M, Abuahmad AY, Sprenz J, Deyton M, Stalls V, Kopp M, Hsu AL, Borgnia MJ, Stewart-Jones GBE, Lee MS, Bronkema N, Moody MA, Wiehe K, Bradley T, Alam SM, Parks RJ, Foulger A, Oguin T, Sempowski GD, Bonsignori M, LaBranche CC, Montefiori DC, Seaman M, Santra S, Perfect J, Francica JR, Lynn GM, Aussedat B, Walkowicz WE, Laga R, Kelsoe G, Saunders KO, Fera D, Kwong PD, Seder RA, Bartesaghi A, Shaw GM, Acharya P, Haynes BF
Modulating HIV-1 envelope glycoprotein conformation to decrease the HIV-1 reservoir.
1. Cell Host Microbe - published May 1, 2021
2. Rajashekar JK, Richard J, Beloor J, Prévost J, Anand SP, Beaudoin-Bussières G, Shan L, Herndler-Brandstetter D, Gendron-Lepage G, Medjahed H, Bourassa C, Gaudette F, Ullah I, Symmes K, Peric A, Lindemuth E, Bibollet-Ruche F, Park J, Chen HC, Kaufmann DE, Hahn BH, Sodroski J, Pazgier M, Flavell RA, Smith AB 3rd, Finzi A, Kumar P
A non-affinity purification process for GMP production of prefusion-closed HIV-1 envelope trimers from clades A and C for clinical evaluation.
1. Vaccine - published May 1, 2021
2. Gulla K, Cibelli N, Cooper JW, Fuller HC, Schneiderman Z, Witter S, Zhang Y, Changela A, Geng H, Hatcher C, Narpala S, Tsybovsky Y, Zhang B, Vrc Production Program, McDermott AB, Kwong PD, Gowetski DB
Cryo-electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex.
1. Sci Adv - published May 1, 2021
2. Bous J, Orcel H, Floquet N, Leyrat C, Lai-Kee-Him J, Gaibelet G, Ancelin A, Saint-Paul J, Trapani S, Louet M, Sounier R, Déméné H, Granier S, Bron P, Mouillac B
Structures and target RNA preferences of the RNA-binding protein family of IGF2BPs: An overview.
1. Structure - published May 1, 2021
2. Korn SM, Ulshöfer CJ, Schneider T, Schlundt A
Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
1. Science - published May 1, 2021
2. Bhatt PR, Scaiola A, Loughran G, Leibundgut M, Kratzel A, Meurs R, Dreos R, O'Connor KM, McMillan A, Bode JW, Thiel V, Gatfield D, Atkins JF, Ban N
Hepatobiliary Cancers, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
1. J Natl Compr Canc Netw - published May 1, 2021
2. Benson AB, D'Angelica MI, Abbott DE, Anaya DA, Anders R, Are C, Bachini M, Borad M, Brown D, Burgoyne A, Chahal P, Chang DT, Cloyd J, Covey AM, Glazer ES, Goyal L, Hawkins WG, Iyer R, Jacob R, Kelley RK, Kim R, Levine M, Palta M, Park JO, Raman S, Reddy S, Sahai V, Schefter T, Singh G, Stein S, Vauthey JN, Venook AP, Yopp A, McMillian NR, Hochstetler C, Darlow SD
A Multicenter Evaluation of Survival After In-Hospital Cardiac Arrest in Coronavirus Disease 2019 Patients.
1. Crit Care Explor - published May 1, 2021
2. Bhardwaj A, Alwakeel M, Saleem T, Afzal S, Alqaisi S, Saand AR, Najjar HA, Griffiths L, Han X, Wang X, Perez-Protto S, Abella BS, Gaieski DF, Duggal A, Abi Fadel F
N⁶-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.
1. Cancer Cell - published May 1, 2021
2. Cheng Y, Xie W, Pickering BF, Chu KL, Savino AM, Yang X, Luo H, Nguyen DT, Mo S, Barin E, Velleca A, Rohwetter TM, Patel DJ, Jaffrey SR, Kharas MG
Structural Insights into the Human Astrovirus Capsid.
1. Viruses - published May 1, 2021
2. Ykema M, Tao YJ
Functional coordination of BET family proteins underlies altered transcription associated with memory impairment in fragile X syndrome.
1. Sci Adv - published May 1, 2021
2. Kim SK, Liu X, Park J, Um D, Kilaru G, Chiang CM, Kang M, Huber KM, Kang K, Kim TK