Member Publications

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109 Member Publications for September 2019

Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases.
1. Clin Transl Allergy - published September 14, 2019
2. Bousquet JJ, Schünemann HJ, Togias A, Erhola M, Hellings PW, Zuberbier T, Agache I, Ansotegui IJ, Anto JM, Bachert C, Becker S, Bedolla-Barajas M, Bewick M, Bosnic-Anticevich S, Bosse I, Boulet LP, Bourrez JM, Brusselle G, Chavannes N, Costa E, Cruz AA, Czarlewski W, Fokkens WJ, Fonseca JA, Gaga M, Haahtela T, Illario M, Klimek L, Kuna P, Kvedariene V, Le LTT, Larenas-Linnemann D, Laune D, Lourenço OM, Menditto E, Mullol J, Okamoto Y, Papadopoulos N, Pham-Thi N, Picard R, Pinnock H, Roche N, Roller-Wirnsberger RE, Rolland C, Samolinski B, Sheikh A, Toppila-Salmi S, Tsiligianni I, Valiulis A, Valovirta E, Vasankari T, Ventura MT, Walker S, Williams S, Akdis CA, Annesi-Maesano I, Arnavielhe S, Basagana X, Bateman E, Bedbrook A, Bennoor KS, Benveniste S, Bergmann KC, Bialek S, Billo N, Bindslev-Jensen C, Bjermer L, Blain H, Bonini M, Bonniaud P, Bouchard J, Briedis V, Brightling CE, Brozek J, Buhl R, Buonaiuto R, Canonica GW, Cardona V, Carriazo AM, Carr W, Cartier C, Casale T, Cecchi L, Cepeda Sarabia AM, Chkhartishvili E, Chu DK, Cingi C, Colgan E, de Sousa JC, Courbis AL, Custovic A, Cvetkosvki B, D'Amato G, da Silva J, Dantas C, Dokic D, Dauvilliers Y, Dedeu A, De Feo G, Devillier P, Di Capua S, Dykewickz M, Dubakiene R, Ebisawa M, El-Gamal Y, Eller E, Emuzyte R, Farrell J, Fink-Wagner A, Fiocchi A, Fontaine JF, Gemicioğlu B, Schmid-Grendelmeir P, Gamkrelidze A, Garcia-Aymerich J, Gomez M, González Diaz S, Gotua M, Guldemond NA, Guzmán MA, Hajjam J, O'B Hourihane J, Humbert M, Iaccarino G, Ierodiakonou D, Illario M, Ivancevich JC, Joos G, Jung KS, Jutel M, Kaidashev I, Kalayci O, Kardas P, Keil T, Khaitov M, Khaltaev N, Kleine-Tebbe J, Kowalski ML, Kritikos V, Kull I, Leonardini L, Lieberman P, Lipworth B, Lodrup Carlsen KC, Loureiro CC, Louis R, Mair A, Marien G, Mahboub B, Malva J, Manning P, De Manuel Keenoy E, Marshall GD, Masjedi MR, Maspero JF, Mathieu-Dupas E, Matricardi PM, Melén E, Melo-Gomes E, Meltzer EO, Menditto E, Mercier J, Miculinic N, Mihaltan F, Milenkovic B, Moda G, Mogica-Martinez MD, Mohammad Y, Montefort S, Monti R, Morais-Almeida M, Mösges R, Münter L, Muraro A, Murray R, Naclerio R, Napoli L, Namazova-Baranova L, Neffen H, Nekam K, Neou A, Novellino E, Nyembue D, O'Hehir R, Ohta K, Okubo K, Onorato G, Ouedraogo S, Pali-Schöll I, Palkonen S, Panzner P, Park HS, Pépin JL, Pereira AM, Pfaar O, Paulino E, Phillips J, Picard R, Plavec D, Popov TA, Portejoie F, Price D, Prokopakis EP, Pugin B, Raciborski F, Rajabian-Söderlund R, Reitsma S, Rodo X, Romano A, Rosario N, Rottem M, Ryan D, Salimäki J, Sanchez-Borges MM, Sisul JC, Solé D, Somekh D, Sooronbaev T, Sova M, Spranger O, Stellato C, Stelmach R, Suppli Ulrik C, Thibaudon M, To T, Todo-Bom A, Tomazic PV, Valero AA, Valenta R, Valentin-Rostan M, van der Kleij R, Vandenplas O, Vezzani G, Viart F, Viegi G, Wallace D, Wagenmann M, Wang Y, Waserman S, Wickman M, Williams DM, Wong G, Wroczynski P, Yiallouros PK, Yorgancioglu A, Yusuf OM, Zar HJ, Zeng S, Zernotti M, Zhang L, Zhong NS, Zidarn M, ARIA Study Group., MASK Study Group.
Upgraded molecular models of the human KCNQ1 potassium channel.
1. PLoS One - published September 14, 2019
2. Kuenze G, Duran AM, Woods H, Brewer KR, McDonald EF, Vanoye CG, George AL Jr, Sanders CR, Meiler J
A Structure-Function Diversity Survey of the RNA-Dependent RNA Polymerases From the Positive-Strand RNA Viruses.
1. Front Microbiol - published September 12, 2019
2. Jia H, Gong P
SLX4IP acts with SLX4 and XPF-ERCC1 to promote interstrand crosslink repair.
1. Nucleic Acids Res - published September 9, 2019
2. Zhang H, Chen Z, Ye Y, Ye Z, Cao D, Xiong Y, Srivastava M, Feng X, Tang M, Wang C, Tainer JA, Chen J
The structure of Acinetobacter-secreted protease CpaA complexed with its chaperone CpaB reveals a novel mode of a T2SS chaperone-substrate interaction.
1. J Biol Chem - published September 6, 2019
2. Urusova DV, Kinsella RL, Salinas ND, Haurat MF, Feldman MF, Tolia NH
Regulation of Eag1 gating by its intracellular domains.
1. Elife - published September 6, 2019
2. Whicher JR, MacKinnon R
Blocking α4β7 integrin binding to SIV does not improve virologic control.
1. Science - published September 6, 2019
2. Iwamoto N, Mason RD, Song K, Gorman J, Welles HC, Arthos J, Cicala C, Min S, King HAD, Belli AJ, Reimann KA, Foulds KE, Kwong PD, Lifson JD, Keele BF, Roederer M
Mechanistic insights into mRNA 3'-end processing.
1. Curr Opin Struct Biol - published September 6, 2019
2. Kumar A, Clerici M, Muckenfuss LM, Passmore LA, Jinek M
A Microtubule-Myelination Connection.
1. Cell - published September 6, 2019
2. Roll-Mecak A
Structural insights into TRPM8 inhibition and desensitization.
1. Science - published September 5, 2019
2. Diver MM, Cheng Y, Julius D
Genetic intolerance analysis as a tool for protein science.
1. Biochim Biophys Acta Biomembr - published September 5, 2019
2. Li GC, Forster-Benson ETC, Sanders CR
The SH3 domains of the protein kinases ITK and LCK compete for adjacent sites on T cell-specific adapter protein.
1. J Biol Chem - published September 4, 2019
2. Andersen TCB, Kristiansen PE, Huszenicza Z, Johansson MU, Gopalakrishnan RP, Kjelstrup H, Boyken S, Sundvold-Gjerstad V, Granum S, Sørlie M, Backe PH, Fulton DB, Karlsson BG, Andreotti AH, Spurkland A
CD4 Incorporation into HIV-1 Viral Particles Exposes Envelope Epitopes Recognized by CD4-induced Antibodies.
1. J Virol - published September 4, 2019
2. Ding S, Gasser R, Gendron-Lepage G, Medjahed H, Tolbert WD, Sodroski J, Pazgier M, Finzi A
Can a sub-group at high risk for LRR be identified from T1-2 breast cancer negative lymph nodes after mastectomy?a meta-analysis.
1. Biosci Rep - published September 4, 2019
2. Gong P, Zhou Z, Jiang M, Yang F
Structural basis for transcription activation by Crl through tethering of σS and RNA polymerase.
1. Proc Natl Acad Sci U S A - published September 4, 2019
2. Cartagena AJ, Banta AB, Sathyan N, Ross W, Gourse RL, Campbell EA, Darst SA
Chemical and structural analysis of a photoactive vertebrate cryptochrome from pigeon.
1. Proc Natl Acad Sci U S A - published September 4, 2019
2. Zoltowski BD, Chelliah Y, Wickramaratne A, Jarocha L, Karki N, Xu W, Mouritsen H, Hore PJ, Hibbs RE, Green CB, Takahashi JS
The Structural Basis of the Farnesylated and Methylated KRas4B Interaction with Calmodulin.
1. Structure - published September 4, 2019
2. Jang H, Banerjee A, Marcus K, Makowski L, Mattos C, Gaponenko V, Nussinov R
Structure activity relationship towards design of cryptosporidium specific thymidylate synthase inhibitors.
1. Eur J Med Chem - published September 4, 2019
2. Czyzyk DJ, Valhondo M, Deiana L, Tirado-Rives J, Jorgensen WL, Anderson KS
The Unfolded Protein Response: Detecting and Responding to Fluctuations in the Protein-Folding Capacity of the Endoplasmic Reticulum.
1. Cold Spring Harb Perspect Biol - published September 3, 2019
2. Karagöz GE, Acosta-Alvear D, Walter P
Temperature-Dependent Interactions Explain Normal and Inverted Solubility in a γD-Crystallin Mutant.
1. Biophys J - published September 3, 2019
2. Khan AR, James S, Quinn MK, Altan I, Charbonneau P, McManus JJ
A unique variant of lymphocytic choriomeningitis virus that induces pheromone binding protein MUP: Critical role for CTL.
1. Proc Natl Acad Sci U S A - published September 3, 2019
2. Ware BC, Sullivan BM, LaVergne S, Marro BS, Egashira T, Campbell KP, Elder J, Oldstone MBA
Critical Effect of the Detergent:Protein Ratio on the Formation of the Hepatitis C Virus p7 Channel.
1. Biochemistry - published September 3, 2019
2. Chen W, OuYang B, Chou JJ
Somatic hypermutation to counter a globally rare viral immunotype drove off-track antibodies in the CAP256-VRC26 HIV-1 V2-directed bNAb lineage.
1. PLoS Pathog - published September 3, 2019
2. Sacks D, Bhiman JN, Wiehe K, Gorman J, Kwong PD, Morris L, Moore PL
Extensions, Extra Factors, and Extreme Complexity: Ribosomal Structures Provide Insights into Eukaryotic Translation.
1. Cold Spring Harb Perspect Biol - published September 3, 2019
2. Weisser M, Ban N
Introducing gene deletions by mouse zygote electroporation of Cas12a/Cpf1.
1. Transgenic Res - published September 3, 2019
2. Dumeau CE, Monfort A, Kissling L, Swarts DC, Jinek M, Wutz A
Modulating pathogenesis with Mobile-CRISPRi.
1. J Bacteriol - published September 3, 2019
2. Qu J, Prasad NK, Yu MA, Chen S, Lyden A, Herrera N, Silvis MR, Crawford E, Looney MR, Peters JM, Rosenberg OS
Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome.
1. Cell Rep - published September 3, 2019
2. Eickhoff P, Kose HB, Martino F, Petojevic T, Abid Ali F, Locke J, Tamberg N, Nans A, Berger JM, Botchan MR, Yardimci H, Costa A
A Gorilla Adenovirus-Based Vaccine against Zika Virus Induces Durable Immunity and Confers Protection in Pregnancy.
1. Cell Rep - published September 3, 2019
2. Hassan AO, Dmitriev IP, Kashentseva EA, Zhao H, Brough DE, Fremont DH, Curiel DT, Diamond MS
Allosteric activation of the nitric oxide receptor soluble guanylate cyclase mapped by cryo-electron microscopy.
1. Elife - published September 3, 2019
2. Horst BG, Yokom AL, Rosenberg DJ, Morris KL, Hammel M, Hurley JH, Marletta MA
GCC Consolidated Feedback to ICH on the 2019 ICH M10 Bioanalytical Method Validation Draft Guideline.
1. Bioanalysis - published September 3, 2019
2. Nehls C, Buonarati M, Cape S, Islam R, Satterwhite C, Briscoe C, Hayes R, Dinan A, Sales K, Anderson S, Vance J, Lindsay J, Zimmer J, Couerbe P, Khadang A, Maasjo S, Bravo O, Lindley K, Moran L, Sangster T, Vija J, Stamatopoulos J, Lin J, Reuschel S, Underberg A, MacNeill R, Matassa L, Spytko A, Garofolo W, Savoie N, Rhyne P, Ambrosius J, Barra V, Dufield D, Luna M, Spriggs F, Fedorov E, Ritzén H, Fatmi S, Kane C, Bouhajib M, DiMarco C, Iordachescu A, Tudoroniu A, Farley E, Stouffer B, Tabler E, McCown S, Bower J, Harrison T, Karnik S, Brown M, Joyce P, DuBey I, Hoffpauir B, Boudreau N, Bergeron J, Wang H, Feng H, Zhou S, Wells E, Pirro J, Fang X, Shi J, Yang C
Structures of neurexophilin-neurexin complexes reveal a regulatory mechanism of alternative splicing.
1. EMBO J - published September 3, 2019
2. Wilson SC, White KI, Zhou Q, Pfuetzner RA, Choi UB, Südhof TC, Brunger AT
Torque transmission mechanism of the curved bacterial flagellar hook revealed by cryo-EM.
1. Nat Struct Mol Biol - published September 3, 2019
2. Shibata S, Matsunami H, Aizawa SI, Wolf M
The molecular mechanism of cotranslational membrane protein recognition and targeting by SecA.
1. Nat Struct Mol Biol - published September 3, 2019
2. Wang S, Jomaa A, Jaskolowski M, Yang CI, Ban N, Shan SO
Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
1. Proc Natl Acad Sci U S A - published September 3, 2019
2. Renko M, Fiedler M, Rutherford TJ, Schaefer JV, Plückthun A, Bienz M
Defining 'T cell exhaustion'.
1. Nat Rev Immunol - published September 3, 2019
2. Blank CU, Haining WN, Held W, Hogan PG, Kallies A, Lugli E, Lynn RC, Philip M, Rao A, Restifo NP, Schietinger A, Schumacher TN, Schwartzberg PL, Sharpe AH, Speiser DE, Wherry EJ, Youngblood BA, Zehn D
High levels of AAV vector integration into CRISPR-induced DNA breaks.
1. Nat Commun - published September 3, 2019
2. Hanlon KS, Kleinstiver BP, Garcia SP, Zaborowski MP, Volak A, Spirig SE, Muller A, Sousa AA, Tsai SQ, Bengtsson NE, Lööv C, Ingelsson M, Chamberlain JS, Corey DP, Aryee MJ, Joung JK, Breakefield XO, Maguire CA, György B
Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields.
1. Immunity - published September 3, 2019
2. Gorman J, Mason RD, Nettey L, Cavett N, Chuang GY, Peng D, Tsybovsky Y, Verardi R, Nguyen R, Ambrozak D, Biris K, LaBranche CC, Ramesh A, Schramm CA, Zhou J, Bailer RT, Kepler TB, Montefiori DC, Shapiro L, Douek DC, Mascola JR, Roederer M, Kwong PD
A Catalytic Trisulfide in Human Sulfide Quinone Oxidoreductase Catalyzes Coenzyme A Persulfide Synthesis and Inhibits Butyrate Oxidation.
1. Cell Chem Biol - published September 3, 2019
2. Landry AP, Moon S, Kim H, Yadav PK, Guha A, Cho US, Banerjee R
Transcription of Bacterial Chromatin.
1. J Mol Biol - published September 2, 2019
2. Shen BA, Landick R
Self-Assembly Behavior and Application of Terphenyl-Cored Trimaltosides for Membrane-Protein Studies: Impact of Detergent Hydrophobic Group Geometry on Protein Stability.
1. Chemistry - published September 2, 2019
2. Ehsan M, Du Y, Mortensen JS, Hariharan P, Qu Q, Ghani L, Das M, Grethen A, Byrne B, Skiniotis G, Keller S, Loland CJ, Guan L, Kobilka BK, Chae PS
SIRT2 and Lysine Fatty Acylation Regulate the Activity of RalB and Cell Migration.
1. ACS Chem Biol - published September 2, 2019
2. Spiegelman NA, Zhang X, Jing H, Cao J, Kotliar IB, Aramsangtienchai P, Wang M, Tong Z, Rosch KM, Lin H
Degronomics: Mapping the Interacting Peptidome of a Ubiquitin Ligase Using an Integrative Mass Spectrometry Strategy.
1. Anal Chem - published September 2, 2019
2. Canzani D, Rusnac DV, Zheng N, Bush MF
Improved strategy for isoleucine 1H/13C methyl labeling in Pichia pastoris.
1. J Biomol NMR - published September 2, 2019
2. Ali R, Clark LD, Zahm JA, Lemoff A, Ramesh K, Rosenbaum DM, Rosen MK
Structural insights into ISRIB, a memory-enhancing inhibitor of the integrated stress response.
1. FEBS J - published September 2, 2019
2. Anand AA, Walter P
Ehrlichia chaffeensis OMP-1-specific human antibody-mediated immunity is defined by intracellular TRIM21-dependent innate immune activation and extracellular neutralization.
1. Infect Immun - published September 2, 2019
2. Velayutham TS, Kumar S, Zhang X, Kose N, Walker DH, Winslow G, Crowe JE Jr, McBride JW
Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase.
1. Nat Chem - published September 2, 2019
2. Dan Q, Newmister SA, Klas KR, Fraley AE, McAfoos TJ, Somoza AD, Sunderhaus JD, Ye Y, Shende VV, Yu F, Sanders JN, Brown WC, Zhao L, Paton RS, Houk KN, Smith JL, Sherman DH, Williams RM
Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus.
1. Proc Natl Acad Sci U S A - published September 2, 2019
2. Laing ED, Navaratnarajah CK, Cheliout Da Silva S, Petzing SR, Xu Y, Sterling SL, Marsh GA, Wang LF, Amaya M, Nikolov DB, Cattaneo R, Broder CC, Xu K
Multispecific targeting with synthetic ankyrin repeat motif chimeric antigen receptors.
1. Clin Cancer Res - published September 2, 2019
2. Balakrishnan A, Rajan A, Salter AI, Kosasih PL, Wu Q, Voutsinas J, Jensen MC, Plückthun A, Riddell S
Co-occurring alterations in the RAS-MAPK pathway limit response to MET inhibitor treatment in MET exon 14 skipping mutation-positive lung cancer.
1. Clin Cancer Res - published September 2, 2019
2. Rotow JK, Gui P, Wu W, Raymond VM, Lanman RB, Kaye FJ, Peled N, Fece de la Cruz F, Nadres B, Corcoran RB, Yeh I, Bastian BC, Starostik P, Newsom K, Olivas V, Wolff AM, Fraser JS, Collisson EA, McCoach CE, Camidge DR, Pacheco J, Bazhenova L, Li T, Bivona TG, Blakely CM
Current outcomes when optimizing "standard" sample preparation for single-particle cryo-em.
1. J Microsc - published September 2, 2019
2. Carragher B, Cheng Y, Frost A, Glaeser RM, Lander GC, Nogales E, Wang HW
No evidence for viral small RNA production and antiviral function of Argonaute 2 in human cells.
1. Sci Rep - published September 2, 2019
2. Schuster S, Overheul GJ, Bauer L, van Kuppeveld FJM, van Rij RP
Author Correction: Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP.
1. Nat Microbiol - published September 2, 2019
2. Urusova D, Carias L, Huang Y, Nicolete VC, Popovici J, Roesch C, Salinas ND, Dechavanne S, Witkowski B, Ferreira MU, Adams JH, Gross ML, King CL, Tolia NH
LRRK2 binds to the Rab32 subfamily in a GTP-dependent manner via its armadillo domain.
1. Small GTPases - published September 2, 2019
2. McGrath E, Waschbüsch D, Baker BM, Khan AR
De novo design of programmable inducible promoters.
1. Nucleic Acids Res - published September 2, 2019
2. Liu X, Gupta STP, Bhimsaria D, Reed JL, Rodríguez-Martínez JA, Ansari AZ, Raman S
Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
1. Nat Commun - published September 2, 2019
2. McLeod B, Miura K, Scally SW, Bosch A, Nguyen N, Shin H, Kim D, Volkmuth W, Rämisch S, Chichester JA, Streatfield S, Woods C, Schief WR, Emerling D, King CR, Julien JP
Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD.
1. Cell Rep - published September 2, 2019
2. Wang N, Rosen O, Wang L, Turner HL, Stevens LJ, Corbett KS, Bowman CA, Pallesen J, Shi W, Zhang Y, Leung K, Kirchdoerfer RN, Becker MM, Denison MR, Chappell JD, Ward AB, Graham BS, McLellan JS
A new family of small-molecule CD4-mimetic compounds contact the highly conserved aspartic acid 368 of HIV-1 gp120 and mediates ADCC.
1. J Virol - published September 2, 2019
2. Ding S, Grenier MC, Tolbert WD, Vézina D, Sherburn R, Richard J, Prévost J, Chapleau JP, Gendron-Lepage G, Medjahed H, Abrams C, Sodroski J, Pazgier M, Smith AB 3rd, Finzi A
Low expression of RNA sensors impacts Zika virus infection in the lower female reproductive tract.
1. Nat Commun - published September 2, 2019
2. Khan S, Lew I, Wu F, Fritts L, Fontaine KA, Tomar S, Trapecar M, Shehata HM, Ott M, Miller CJ, Sanjabi S
FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora.
1. Nat Commun - published September 2, 2019
2. Liu X, Chen A, Caicedo-Casso A, Cui G, Du M, He Q, Lim S, Kim HJ, Hong CI, Liu Y
A new class of disordered elements controls DNA replication through initiator self-assembly.
1. Elife - published September 2, 2019
2. Parker MW, Bell M, Mir M, Kao JA, Darzacq X, Botchan MR, Berger JM
γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A.
1. Mol Cell - published September 2, 2019
2. Gao X, Zhao L, Liu S, Li Y, Xia S, Chen D, Wang M, Wu S, Dai Q, Vu H, Zacharias L, DeBerardinis R, Lim E, Metallo C, Boggon TJ, Lonial S, Lin R, Mao H, Pan Y, Shan C, Chen J
Peptidoglycan Production by an Insect-Bacterial Mosaic.
1. Cell - published September 2, 2019
2. Bublitz DC, Chadwick GL, Magyar JS, Sandoz KM, Brooks DM, Mesnage S, Ladinsky MS, Garber AI, Bjorkman PJ, Orphan VJ, McCutcheon JP
Exome sequencing of sporadic childhood-onset schizophrenia suggests the contribution of X-linked genes in males.
1. Am J Med Genet B Neuropsychiatr Genet - published September 1, 2019
2. Ambalavanan A, Chaumette B, Zhou S, Xie P, He Q, Spiegelman D, Dionne-Laporte A, Bourassa CV, Therrien M, Rochefort D, Xiong L, Dion PA, Joober R, Rapoport JL, Girard SL, Rouleau GA
The molecular determinants of neurosteroid binding in the GABA(A) receptor.
1. J Steroid Biochem Mol Biol - published September 1, 2019
2. Sugasawa Y, Bracamontes JR, Krishnan K, Covey DF, Reichert DE, Akk G, Chen Q, Tang P, Evers AS, Cheng WWL
A simple linearization method unveils hidden enzymatic assay interferences.
1. Biophys Chem - published September 1, 2019
2. Pinto MF, Ripoll-Rozada J, Ramos H, Watson EE, Franck C, Payne RJ, Saraiva L, Pereira PJB, Pastore A, Rocha F, Martins PM
The Impact of pH on Catalytically Critical Protein Conformational Changes: The Case of the Urease, a Nickel Enzyme.
1. Chemistry - published September 1, 2019
2. Mazzei L, Cianci M, Benini S, Ciurli S
Systems Metabolic Engineering of Escherichia coli Improves Coconversion of Lignocellulose-Derived Sugars.
1. Biotechnol J - published September 1, 2019
2. Kim J, Tremaine M, Grass JA, Purdy HM, Landick R, Kiley PJ, Reed JL
Fluoxetine Inhibits Enterovirus Replication by Targeting the Viral 2C Protein in a Stereospecific Manner.
1. ACS Infect Dis - published September 1, 2019
2. Bauer L, Manganaro R, Zonsics B, Strating JRPM, El Kazzi P, Lorenzo Lopez M, Ulferts R, van Hoey C, Maté MJ, Langer T, Coutard B, Brancale A, van Kuppeveld FJM
The crystal structure of the protein kinase HIPK2 reveals a unique architecture of its CMGC-insert region.
1. J Biol Chem - published September 1, 2019
2. Agnew C, Liu L, Liu S, Xu W, You L, Yeung W, Kannan N, Jablons D, Jura N
Publisher Correction: Systems NMR: single-sample quantification of RNA, proteins and metabolites for biomolecular network analysis.
1. Nat Methods - published September 1, 2019
2. Nikolaev Y, Ripin N, Soste M, Picotti P, Iber D, Allain FH
Single-cell imaging reveals unexpected heterogeneity of telomerase reverse transcriptase expression across human cancer cell lines.
1. Proc Natl Acad Sci U S A - published September 1, 2019
2. Rowland TJ, Dumbović G, Hass EP, Rinn JL, Cech TR
The asymmetric function of Dph1-Dph2 heterodimer in diphthamide biosynthesis.
1. J Biol Inorg Chem - published September 1, 2019
2. Dong M, Dando EE, Kotliar I, Su X, Dzikovski B, Freed JH, Lin H
Functional Annotation of ABHD14B, an Orphan Serine Hydrolase Enzyme.
1. Biochemistry - published September 1, 2019
2. Rajendran A, Vaidya K, Mendoza J, Bridwell-Rabb J, Kamat SS
Getting in: The structural biology of malaria invasion.
1. PLoS Pathog - published September 1, 2019
2. Kumar H, Tolia NH
A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model.
1. Nat Med - published September 1, 2019
2. Yant SR, Mulato A, Hansen D, Tse WC, Niedziela-Majka A, Zhang JR, Stepan GJ, Jin D, Wong MH, Perreira JM, Singer E, Papalia GA, Hu EY, Zheng J, Lu B, Schroeder SD, Chou K, Ahmadyar S, Liclican A, Yu H, Novikov N, Paoli E, Gonik D, Ram RR, Hung M, McDougall WM, Brass AL, Sundquist WI, Cihlar T, Link JO
The molecular basis of chaperone-mediated interleukin 23 assembly control.
1. Nat Commun - published September 1, 2019
2. Meier S, Bohnacker S, Klose CJ, Lopez A, Choe CA, Schmid PWN, Bloemeke N, Rührnößl F, Haslbeck M, Bieren JE, Sattler M, Huang PS, Feige MJ
Mechanisms of nuclear mRNA export: A structural perspective.
1. Traffic - published September 1, 2019
2. Xie Y, Ren Y
EXPLORE: A Prospective, Multinational, Natural History Study of Patients with Acute Hepatic Porphyria with Recurrent Attacks.
1. Hepatology - published September 1, 2019
2. Gouya L, Ventura P, Balwani M, Bissell DM, Rees DC, Stölzel U, Phillips JD, Kauppinen R, Langendonk JG, Desnick RJ, Deybach JC, Bonkovsky HL, Parker C, Naik H, Badminton M, Stein PE, Minder E, Windyga J, Bruha R, Cappellini MD, Sardh E, Harper P, Sandberg S, Aarsand AK, Andersen J, Alegre F, Ivanova A, Talbi N, Chan A, Querbes W, Ko J, Penz C, Liu S, Lin T, Simon A, Anderson KE
Intestinal UDP-glucuronosyltransferase as a potential target for the treatment and prevention of lymphatic filariasis.
1. PLoS Negl Trop Dis - published September 1, 2019
2. Flynn AF, Joyce MG, Taylor RT, Bennuru S, Lindrose AR, Sterling SL, Morris CP, Nutman TB, Mitre E
Molecular basis for metabolite channeling in a ring opening enzyme of the phenylacetate degradation pathway.
1. Nat Commun - published September 1, 2019
2. Sathyanarayanan N, Cannone G, Gakhar L, Katagihallimath N, Sowdhamini R, Ramaswamy S, Vinothkumar KR
Hypoxic drive caused Type 3 neovascularization in a preclinical model of exudative age-related macular degeneration.
1. Hum Mol Genet - published September 1, 2019
2. Zhang L, Cui X, Han Y, Park KS, Gao X, Zhang X, Yuan Z, Hu Y, Hsu CW, Li X, Bassuk AG, Mahajan VB, Wang NK, Tsang SH
Binge Drinking among Economically Disadvantaged African American Older Adults with Diabetes.
1. Behav Sci (Basel) - published September 1, 2019
2. Assari S, Smith JL, Saqib M, Bazargan M
A nanobody that recognizes a 14-residue peptide epitope in the E2 ubiquitin-conjugating enzyme UBC6e modulates its activity.
1. Mol Immunol - published September 1, 2019
2. Ling J, Cheloha RW, McCaul N, Sun ZJ, Wagner G, Ploegh HL
Sex-Based Differences in Left Ventricular Assist Device Utilization: Insights From the Nationwide Inpatient Sample 2004 to 2016.
1. Circ Heart Fail - published September 1, 2019
2. Joshi AA, Lerman JB, Sajja AP, Dahiya G, Gokhale AV, Dey AK, Kyvernitakis A, Halbreiner MS, Bailey S, Alpert CM, Poornima IG, Murali S, Benza RL, Kanwar M, Raina A
Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
1. Science - published September 1, 2019
2. Saurer M, Ramrath DJF, Niemann M, Calderaro S, Prange C, Mattei S, Scaiola A, Leitner A, Bieri P, Horn EK, Leibundgut M, Boehringer D, Schneider A, Ban N
G Protein-Coupled Estrogen Receptor Production Using an Escherichia coli Cell-Free Expression System.
1. Curr Protoc Protein Sci - published September 1, 2019
2. Souza SA, Kurohara DT, Dabalos CL, Ng HL
Homocysteine, vitamin B12, and folate levels in patients with multiple sclerosis in Chinese population: A case-control study and meta-analysis.
1. Mult Scler Relat Disord - published September 1, 2019
2. Pan L, Yin Y, Chen J, Ma Z, Chen Y, Deng X, Zhang HT, Leng H, Wu K
Integrative Protein Modeling in RosettaNMR from Sparse Paramagnetic Restraints.
1. Structure - published September 1, 2019
2. Kuenze G, Bonneau R, Leman JK, Meiler J
A Bacterial Effector Mimics a Host HSP90 Client to Undermine Immunity.
1. Cell - published September 1, 2019
2. Lopez VA, Park BC, Nowak D, Sreelatha A, Zembek P, Fernandez J, Servage KA, Gradowski M, Hennig J, Tomchick DR, Pawłowski K, Krzymowska M, Tagliabracci VS
TCR-pMHC bond conformation controls TCR ligand discrimination.
1. Cell Mol Immunol - published September 1, 2019
2. Sasmal DK, Feng W, Roy S, Leung P, He Y, Cai C, Cao G, Lian H, Qin J, Hui E, Schreiber H, Adams EJ, Huang J
Heme binding to human CLOCK affects interactions with the E-box.
1. Proc Natl Acad Sci U S A - published September 1, 2019
2. Freeman SL, Kwon H, Portolano N, Parkin G, Venkatraman Girija U, Basran J, Fielding AJ, Fairall L, Svistunenko DA, Moody PCE, Schwabe JWR, Kyriacou CP, Raven EL
RCSB Protein Data Bank: Enabling biomedical research and drug discovery.
1. Protein Sci - published September 1, 2019
2. Goodsell DS, Zardecki C, Di Costanzo L, Duarte JM, Hudson BP, Persikova I, Segura J, Shao C, Voigt M, Westbrook JD, Young JY, Burley SK
Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancester of CH235 lineage CD4bs broadly neutralizing antibodies.
1. PLoS Pathog - published September 1, 2019
2. LaBranche CC, Henderson R, Hsu A, Behrens S, Chen X, Zhou T, Wiehe K, Saunders KO, Alam SM, Bonsignori M, Borgnia MJ, Sattentau QJ, Eaton A, Greene K, Gao H, Liao HX, Williams WB, Peacock J, Tang H, Perez LG, Edwards RJ, Kepler TB, Korber BT, Kwong PD, Mascola JR, Acharya P, Haynes BF, Montefiori DC
Mrx6 regulates mitochondrial DNA copy number in S. cerevisiae by engaging the evolutionarily conserved Lon protease Pim1.
1. Mol Biol Cell - published September 1, 2019
2. Göke A, Schrott S, Mizrak A, Belyy V, Osman C, Walter P
Nuclear receptor corepressor 1 represses cardiac hypertrophy.
1. EMBO Mol Med - published September 1, 2019
2. Li C, Sun XN, Chen BY, Zeng MR, Du LJ, Liu T, Gu HH, Liu Y, Li YL, Zhou LJ, Zheng XJ, Zhang YY, Zhang WC, Liu Y, Shi C, Shao S, Shi XR, Yi Y, Liu X, Wang J, Auwerx J, Wang ZV, Jia F, Li RG, Duan SZ
Highlight: Young research groups in Germany - continued.
1. Biol Chem - published September 1, 2019
2. Hennig J, Feige MJ
Qualifying antibodies for image-based immune profiling and multiplexed tissue imaging.
1. Nat Protoc - published September 1, 2019
2. Du Z, Lin JR, Rashid R, Maliga Z, Wang S, Aster JC, Izar B, Sorger PK, Santagata S
Mind the gap: micro-expansion joints drastically decrease the bending of FIB-milled cryo-lamellae.
1. J Struct Biol - published September 1, 2019
2. Wolff G, Limpens RWAL, Zheng S, Snijder EJ, Agard DA, Koster AJ, Bárcena M
The 3.1 Å cryo-EM structure of the porcine epidemic diarrhea virus spike protein in the prefusion conformation.
1. J Virol - published September 1, 2019
2. Wrapp D, McLellan JS
Disruption of Robo2-Baiap2 integrated signaling drives cystic disease.
1. JCI Insight - published September 1, 2019
2. Li Q, Cui S, Ma Q, Liu Y, Yu H, Geng G, Agborbesong E, Ren C, Wei K, Zhang Y, Yang J, Bai X, Cai G, Xie Y, Li X, Chen X
Starving the Devourer: Cutting Cancer Off from Its Favorite Foods.
1. Cell Chem Biol - published September 1, 2019
2. Katt WP, Lukey MJ, Cerione RA
SnapShot: The RNA Exosome.
1. Cell - published September 1, 2019
2. Puno MR, Weick EM, Das M, Lima CD
From symbiont to parasite: the evolution of for-profit science publishing.
1. Mol Biol Cell - published September 1, 2019
2. Walter P, Mullins D
Novel REEP6 gene mutation associated with autosomal recessive retinitis pigmentosa.
1. Doc Ophthalmol - published September 1, 2019
2. Lin Y, Xu CL, Velez G, Yang J, Tanaka AJ, Breazzano MP, Mahajan VB, Sparrow JR, Tsang SH
Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements.
1. Cell - published September 1, 2019
2. Kim GB, Rincon Fernandez Pacheco D, Saxon D, Yang A, Sabet S, Dutra-Clarke M, Levy R, Watkins A, Park H, Abbasi Akhtar A, Linesch PW, Kobritz N, Chandra SS, Grausam K, Ayala-Sarmiento A, Molina J, Sedivakova K, Hoang K, Tsyporin J, Gareau DS, Filbin MG, Bannykh S, Santiskulvong C, Wang Y, Tang J, Suva ML, Chen B, Danielpour M, Breunig JJ
Do Younger Patients with Muscle-Invasive Bladder Cancer have Better Outcomes?
1. J Clin Med - published September 1, 2019
2. Janisch F, Yu H, Vetterlein MW, Dahlem R, Engel O, Fisch M, Shariat SF, Soave A, Rink M
Organization of Chromatin by Intrinsic and Regulated Phase Separation.
1. Cell - published September 1, 2019
2. Gibson BA, Doolittle LK, Schneider MWG, Jensen LE, Gamarra N, Henry L, Gerlich DW, Redding S, Rosen MK
MicroED with the Falcon III direct electron detector.
1. IUCrJ - published September 1, 2019
2. Hattne J, Martynowycz MW, Penczek PA, Gonen T
On the Interpretation of Force-Induced Unfolding Studies of Membrane Proteins Using Fast Simulations.
1. Biophys J - published September 1, 2019
2. Wang Z, Jumper JM, Freed KF, Sosnick TR