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116 Member Publications for October 2018

Cytidine monophosphate <i>N</i>-acetylneuraminic acid synthetase enhances invasion of human triple-negative breast cancer cells.
1. Onco Targets Ther - published October 24, 2018
2. O'Day EM, Idos GE, Hill C, Chen JW, Wagner G
Structures of translationally inactive mammalian ribosomes.
1. Elife - published October 24, 2018
2. Brown A, Baird MR, Yip MC, Murray J, Shao S
A RECK-WNT7 Receptor-Ligand Interaction Enables Isoform-Specific Regulation of Wnt Bioavailability.
1. Cell Rep - published October 9, 2018
2. Vallon M, Yuki K, Nguyen TD, Chang J, Yuan J, Siepe D, Miao Y, Essler M, Noda M, Garcia KC, Kuo CJ
Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism.
1. Nat Commun - published October 8, 2018
2. Peek J, Lilic M, Montiel D, Milshteyn A, Woodworth I, Biggins JB, Ternei MA, Calle PY, Danziger M, Warrier T, Saito K, Braffman N, Fay A, Glickman MS, Darst SA, Campbell EA, Brady SF
Cryo-EM.
1. Curr Biol - published October 8, 2018
2. Nogales E
Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturation.
1. Nat Commun - published October 8, 2018
2. Johnson EL, Doria-Rose NA, Gorman J, Bhiman JN, Schramm CA, Vu AQ, Law WH, Zhang B, Bekker V, Abdool Karim SS, Ippolito GC, Morris L, Moore PL, Kwong PD, Mascola JR, Georgiou G
Movement of the RecG Motor Domain upon DNA Binding Is Required for Efficient Fork Reversal.
1. Int J Mol Sci - published October 6, 2018
2. Warren GM, Stein RA, Mchaourab HS, Eichman BF
Smoothening out the patches.
1. Science - published October 5, 2018
2. Sommer A, Lemmon MA
The ectodomains determine ligand function in vivo and selectivity of DLL1 and DLL4 toward NOTCH1 and NOTCH2 in vitro.
1. Elife - published October 5, 2018
2. Tveriakhina L, Schuster-Gossler K, Jarrett SM, Andrawes MB, Rohrbach M, Blacklow SC, Gossler A
Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis.
1. Cell - published October 5, 2018
2. Chen Z, Suzuki H, Kobayashi Y, Wang AC, DiMaio F, Kawashima SA, Walz T, Kapoor TM
Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells.
1. Cell - published October 4, 2018
2. Sandhu J, Li S, Fairall L, Pfisterer SG, Gurnett JE, Xiao X, Weston TA, Vashi D, Ferrari A, Orozco JL, Hartman CL, Strugatsky D, Lee SD, He C, Hong C, Jiang H, Bentolila LA, Gatta AT, Levine TP, Ferng A, Lee R, Ford DA, Young SG, Ikonen E, Schwabe JWR, Tontonoz P
Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors.
1. J Am Chem Soc - published October 4, 2018
2. Martin SES, Tan ZW, Itkonen HM, Duveau DY, Paulo JA, Janetzko J, Boutz PL, Törk L, Moss FA, Thomas CJ, Gygi SP, Lazarus MB, Walker S
Critical Role for Saccharomyces cerevisiae Asc1p in Translational Initiation at Elevated Temperatures.
1. Proteomics - published October 4, 2018
2. Gerbasi VR, Browne CM, Samir P, Shen B, Sun M, Hazelbaker DZ, Galassie AC, Frank J, Link AJ
Fusion surface structure, function, and dynamics of gamete fusogen HAP2.
1. Elife - published October 3, 2018
2. Feng J, Dong X, Pinello J, Zhang J, Lu C, Iacob RE, Engen JR, Snell WJ, Springer TA
OTUB1 non-catalytically stabilizes the E2 ubiquitin-conjugating enzyme UBE2E1 by preventing its autoubiquitination.
1. J Biol Chem - published October 3, 2018
2. Pasupala N, Morrow ME, Que LT, Malynn BA, Ma A, Wolberger C
Discovery and Characterization of a Thioesterase-Specific Monoclonal Antibody That Recognizes the 6-Deoxyerythronolide B Synthase.
1. Biochemistry - published October 3, 2018
2. Li X, Sevillano N, La Greca F, Hsu J, Mathews II, Matsui T, Craik CS, Khosla C
Proximity-enhanced SuFEx chemical cross-linker for specific and multitargeting cross-linking mass spectrometry.
1. Proc Natl Acad Sci U S A - published October 3, 2018
2. Yang B, Wu H, Schnier PD, Liu Y, Liu J, Wang N, DeGrado WF, Wang L
Structural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition.
1. Nat Commun - published October 3, 2018
2. LaRochelle JR, Fodor M, Vemulapalli V, Mohseni M, Wang P, Stams T, LaMarche MJ, Chopra R, Acker MG, Blacklow SC
Structural basis for anthrax toxin receptor 1 recognition by Seneca Valley Virus.
1. Proc Natl Acad Sci U S A - published October 3, 2018
2. Jayawardena N, Burga LN, Easingwood RA, Takizawa Y, Wolf M, Bostina M
Calcium sensing by the STIM1 ER-luminal domain.
1. Nat Commun - published October 3, 2018
2. Gudlur A, Zeraik AE, Hirve N, Rajanikanth V, Bobkov AA, Ma G, Zheng S, Wang Y, Zhou Y, Komives EA, Hogan PG
Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif.
1. Nat Commun - published October 3, 2018
2. Shelke SA, Shao Y, Laski A, Koirala D, Weissman BP, Fuller JR, Tan X, Constantin TP, Waggoner AS, Bruchez MP, Armitage BA, Piccirilli JA
Mutations in influenza A virus neuraminidase and hemagglutinin confer resistance against a broadly neutralizing hemagglutinin stem antibody.
1. J Virol - published October 3, 2018
2. Prachanronarong KL, Canale AS, Liu P, Somasundaran M, Hou S, Poh YP, Han T, Zhu Q, Renzette N, Zeldovich KB, Kowalik TF, Kurt-Yilmaz N, Jensen JD, Bolon DNA, Marasco WA, Finberg RW, Schiffer CA, Wang JP
Computation-guided analysis of paroxetine binding to hSERT reveals functionally important structural elements and dynamics.
1. Neuropharmacology - published October 3, 2018
2. Abramyan AM, Slack RD, Meena S, Davis BA, Newman AH, Singh SK, Shi L
Ultrashort Broadband Cooperative Pulses for Multidimensional Biomolecular NMR Experiments.
1. Angew Chem Int Ed Engl - published October 2, 2018
2. Asami S, Kallies W, Günther JC, Stavropoulou M, Glaser SJ, Sattler M
Tiopronin-Protected Gold Nanoparticles as a Potential Marker for Cryo-EM and Tomography.
1. Structure - published October 2, 2018
2. Dahan I, Sorrentino S, Boujemaa-Paterski R, Medalia O
Entry from the Lipid Bilayer: A Possible Pathway for Inhibition of a Peptide G Protein-Coupled Receptor by a Lipophilic Small Molecule.
1. Biochemistry - published October 2, 2018
2. Bokoch MP, Jo H, Valcourt JR, Srinivasan Y, Pan AC, Capponi S, Grabe M, Dror RO, Shaw DE, DeGrado WF, Coughlin SR
Cubic lyotropic liquid crystals as drug delivery carriers: Physicochemical and morphological studies.
1. Int J Pharm - published October 2, 2018
2. Chountoulesi M, Pippa N, Pispas S, Chrysina ED, Forys A, Trzebicka B, Demetzos C
Molecular Mechanism of Resistance in a Clinically Significant Double-Mutant Variant of HCV NS3/4A Protease.
1. Structure - published October 2, 2018
2. Matthew AN, Leidner F, Newton A, Petropoulos CJ, Huang W, Ali A, KurtYilmaz N, Schiffer CA
Structural analyses of 4-phosphate adaptor protein 2 yield mechanistic insights into sphingolipid recognition by the glycolipid transfer protein family.
1. J Biol Chem - published October 2, 2018
2. Ochoa-Lizarralde B, Gao YG, Popov AN, Samygina VR, Zhai X, Mishra SK, Boldyrev IA, Molotkovsky JG, Simanshu DK, Patel DJ, Brown RE, Malinina L
Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
1. Science - published October 2, 2018
2. Ramrath DJF, Niemann M, Leibundgut M, Bieri P, Prange C, Horn EK, Leitner A, Boehringer D, Schneider A, Ban N
Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology.
1. Proc Natl Acad Sci U S A - published October 2, 2018
2. Deng P, Zhou Y, Jiang J, Li H, Tian W, Cao Y, Qin Y, Kim J, Roeder RG, Patel DJ, Wang Z
In Silico Identification of JMJD3 Demethylase Inhibitors.
1. J Chem Inf Model - published October 2, 2018
2. Esposito C, Wiedmer L, Caflisch A
DARPins recognizing mTFP1 as novel reagents for in vitro and in vivo protein manipulations.
1. Biol Open - published October 2, 2018
2. Vigano MA, Bieli D, Schaefer JV, Jakob RP, Matsuda S, Maier T, Plückthun A, Affolter M
In situ serial crystallography for rapid de novo membrane protein structure determination.
1. Commun Biol - published October 2, 2018
2. Huang CY, Olieric V, Howe N, Warshamanage R, Weinert T, Panepucci E, Vogeley L, Basu S, Diederichs K, Caffrey M, Wang M
Effects of copper occupancy on the conformational landscape of peptidylglycine α-hydroxylating monooxygenase.
1. Commun Biol - published October 2, 2018
2. Maheshwari S, Shimokawa C, Rudzka K, Kline CD, Eipper BA, Mains RE, Gabelli SB, Blackburn N, Amzel LM
Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase.
1. Elife - published October 2, 2018
2. Wittenborn EC, Merrouch M, Ueda C, Fradale L, Léger C, Fourmond V, Pandelia ME, Dementin S, Drennan CL
RIP2 filament formation is required for NOD2 dependent NF-κB signalling.
1. Nat Commun - published October 2, 2018
2. Pellegrini E, Desfosses A, Wallmann A, Schulze WM, Rehbein K, Mas P, Signor L, Gaudon S, Zenkeviciute G, Hons M, Malet H, Gutsche I, Sachse C, Schoehn G, Oschkinat H, Cusack S
Sin3A recruits Tet1 to the PAH1 domain via a highly conserved Sin3-Interaction Domain.
1. Sci Rep - published October 2, 2018
2. Chandru A, Bate N, Vuister GW, Cowley SM
Two Faces of CwlM, an Essential PknB Substrate, in Mycobacterium tuberculosis.
1. Cell Rep - published October 2, 2018
2. Turapov O, Forti F, Kadhim B, Ghisotti D, Sassine J, Straatman-Iwanowska A, Bottrill AR, Moynihan PJ, Wallis R, Barthe P, Cohen-Gonsaud M, Ajuh P, Vollmer W, Mukamolova GV
Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone acetylation and crotonylation in vivo.
1. Sci Rep - published October 2, 2018
2. Kelly RDW, Chandru A, Watson PJ, Song Y, Blades M, Robertson NS, Jamieson AG, Schwabe JWR, Cowley SM
Affinity capture of polyribosomes followed by RNAseq (ACAPseq), a discovery platform for protein-protein interactions.
1. Elife - published October 2, 2018
2. Peng X, Emiliani F, Smallwood PM, Rattner A, Lei H, Sabbagh MF, Nathans J
A novel mode of capping protein-regulation by twinfilin.
1. Elife - published October 2, 2018
2. Johnston AB, Hilton DM, McConnell P, Johnson B, Harris MT, Simone A, Amarasinghe GK, Cooper JA, Goode BL
Author Correction: Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening.
1. Nat Protoc - published October 2, 2018
2. Joung J, Konermann S, Gootenberg JS, Abudayyeh OO, Platt RJ, Brigham MD, Sanjana NE, Zhang F
Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1.
1. Nat Commun - published October 2, 2018
2. Daou S, Barbour H, Ahmed O, Masclef L, Baril C, Sen Nkwe N, Tchelougou D, Uriarte M, Bonneil E, Ceccarelli D, Mashtalir N, Tanji M, Masson JY, Thibault P, Sicheri F, Yang H, Carbone M, Therrien M, Affar EB
Author Correction: Acylated-acyl carrier protein stabilizes the Pseudomonas aeruginosa WaaP lipopolysaccharide heptose kinase.
1. Sci Rep - published October 2, 2018
2. Kreamer NNK, Chopra R, Caughlan RE, Fabbro D, Fang E, Gee P, Hunt I, Li M, Leon BC, Muller L, Vash B, Woods AL, Stams T, Dean CR, Uehara T
A call to arms: Unifying the fight against resistance.
1. Sci Signal - published October 2, 2018
2. Kaushansky A, Hedstrom L, Goldman A, Singh J, Yang PL, Rathod PK, Cynamon M, Wodarz D, Mahadevan D, Tomaras A, Navia MA, Schiffer CA
Revised Dose Ramp-Up to Mitigate the Risk of Tumor Lysis Syndrome When Initiating Venetoclax in Patients With Mantle Cell Lymphoma.
1. J Clin Oncol - published October 2, 2018
2. Davids MS, von Keudell G, Portell CA, Cohen JB, Fisher DC, Foss F, Roberts AW, Seymour JF, Humerickhouse RA, Tam CS
Completeness of HIV-1 Envelope Glycan Shield at Transmission Determines Neutralization Breadth.
1. Cell Rep - published October 2, 2018
2. Wagh K, Kreider EF, Li Y, Barbian HJ, Learn GH, Giorgi E, Hraber PT, Decker TG, Smith AG, Gondim MV, Gillis L, Wandzilak J, Chuang GY, Rawi R, Cai F, Pellegrino P, Williams I, Overbaugh J, Gao F, Kwong PD, Haynes BF, Shaw GM, Borrow P, Seaman MS, Hahn BH, Korber B
Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
1. Sci Rep - published October 2, 2018
2. Kirchdoerfer RN, Wang N, Pallesen J, Wrapp D, Turner HL, Cottrell CA, Corbett KS, Graham BS, McLellan JS, Ward AB
Rapamycin induces autophagy to alleviate acute kidney injury following cerebral ischemia and reperfusion via the mTORC1/ATG13/ULK1 signaling pathway.
1. Mol Med Rep - published October 2, 2018
2. Su Y, Lu J, Gong P, Chen X, Liang C, Zhang J
Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45.
1. Nat Commun - published October 2, 2018
2. Kundu P, Semesi A, Jore MM, Morin MJ, Price VL, Liang A, Li J, Miura K, Sauerwein RW, King CR, Julien JP
Recognition protein C1q of innate immunity agglutinates nanodiamonds without activating complement.
1. Nanomedicine - published October 2, 2018
2. Belime A, Thielens NM, Gravel E, Frachet P, Ancelet S, Tacnet P, Caneiro C, Chuprin J, Gaboriaud C, Schoehn G, Doris E, Ling WL
Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome.
1. Nat Genet - published October 2, 2018
2. Gayden T, Sepulveda FE, Khuong-Quang DA, Pratt J, Valera ET, Garrigue A, Kelso S, Sicheri F, Mikael LG, Hamel N, Bajic A, Dali R, Deshmukh S, Dervovic D, Schramek D, Guerin F, Taipale M, Nikbakht H, Majewski J, Moshous D, Charlebois J, Abish S, Bole-Feysot C, Nitschke P, Bader-Meunier B, Mitchell D, Thieblemont C, Battistella M, Gravel S, Nguyen VH, Conyers R, Diana JS, McCormack C, Prince HM, Besnard M, Blanche S, Ekert PG, Fraitag S, Foulkes WD, Fischer A, Neven B, Michonneau D, de Saint Basile G, Jabado N
A Membrane Burial Potential with H-Bonds and Applications to Curved Membranes and Fast Simulations.
1. Biophys J - published October 2, 2018
2. Wang Z, Jumper JM, Wang S, Freed KF, Sosnick TR
A Multi-model Approach to Assessing Local and Global Cryo-EM Map Quality.
1. Structure - published October 2, 2018
2. Herzik MA Jr, Fraser JS, Lander GC
Insight into the functional organization of nuclear lamins in health and disease.
1. Curr Opin Cell Biol - published October 1, 2018
2. Tatli M, Medalia O
hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α₁-antitrypsin deficiency.
1. J Hepatol - published October 1, 2018
2. Segeritz CP, Rashid ST, de Brito MC, Serra MP, Ordonez A, Morell CM, Kaserman JE, Madrigal P, Hannan NRF, Gatto L, Tan L, Wilson AA, Lilley K, Marciniak SJ, Gooptu B, Lomas DA, Vallier L
Nutrient transport suggests an evolutionary basis for charged archaeal surface layer proteins.
1. ISME J - published October 1, 2018
2. Li PN, Herrmann J, Tolar BB, Poitevin F, Ramdasi R, Bargar JR, Stahl DA, Jensen GJ, Francis CA, Wakatsuki S, van den Bedem H
The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates.
1. Lancet Infect Dis - published October 1, 2018
2. Mazur NI, Higgins D, Nunes MC, Melero JA, Langedijk AC, Horsley N, Buchholz UJ, Openshaw PJ, McLellan JS, Englund JA, Mejias A, Karron RA, Simões EA, Knezevic I, Ramilo O, Piedra PA, Chu HY, Falsey AR, Nair H, Kragten-Tabatabaie L, Greenough A, Baraldi E, Papadopoulos NG, Vekemans J, Polack FP, Powell M, Satav A, Walsh EE, Stein RT, Graham BS, Bont LJ, Respiratory Syncytial Virus Network (ReSViNET) Foundation.
Improved multi-view privileged support vector machine.
1. Neural Netw - published October 1, 2018
2. Tang J, Tian Y, Liu X, Li D, Lv J, Kou G
Targeting Helicobacter pylori urease activity and maturation: In-cell high-throughput approach for drug discovery.
1. Biochim Biophys Acta Gen Subj - published October 1, 2018
2. Tarsia C, Danielli A, Florini F, Cinelli P, Ciurli S, Zambelli B
The "speed limit" for macromolecular crystal growth.
1. Protein Sci - published October 1, 2018
2. Arias RJ, Kaiser JT, Rees DC
Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel.
1. J Gen Physiol - published October 1, 2018
2. Li J, Ostmeyer J, Cuello LG, Perozo E, Roux B
Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKε and Reveal Mechanisms for Selective Inhibition.
1. Mol Pharmacol - published October 1, 2018
2. Beyett TS, Gan X, Reilly SM, Chang L, Gomez AV, Saltiel AR, Showalter HD, Tesmer JJG
Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture.
1. J Cell Biol - published October 1, 2018
2. Varlakhanova NV, Alvarez FJD, Brady TM, Tornabene BA, Hosford CJ, Chappie JS, Zhang P, Ford MGJ
Substrate Binding by the Second Sialic Acid-Binding Site of Influenza A Virus N1 Neuraminidase Contributes to Enzymatic Activity.
1. J Virol - published October 1, 2018
2. Du W, Dai M, Li Z, Boons GJ, Peeters B, van Kuppeveld FJM, de Vries E, de Haan CAM
VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites.
1. J Cell Biol - published October 1, 2018
2. Kumar N, Leonzino M, Hancock-Cerutti W, Horenkamp FA, Li P, Lees JA, Wheeler H, Reinisch KM, De Camilli P
p15PAF binding to PCNA modulates the DNA sliding surface.
1. Nucleic Acids Res - published October 1, 2018
2. De March M, Barrera-Vilarmau S, Crespan E, Mentegari E, Merino N, Gonzalez-Magaña A, Romano-Moreno M, Maga G, Crehuet R, Onesti S, Blanco FJ, De Biasio A
Author Correction: Cryo-EM structure of a fungal mitochondrial calcium uniporter.
1. Nature - published October 1, 2018
2. Nguyen NX, Armache JP, Lee C, Yang Y, Zeng W, Mootha VK, Cheng Y, Bai XC, Jiang Y
Limiting Respiratory Viral Infection by Targeting Antiviral and Immunological Functions of BST-2/Tetherin: Knowledge and Gaps.
1. Bioessays - published October 1, 2018
2. Berry KN, Kober DL, Su A, Brett TJ
Structure-function analyses of the ion channel TRPC3 reveal that its cytoplasmic domain allosterically modulates channel gating.
1. J Biol Chem - published October 1, 2018
2. Sierra-Valdez F, Azumaya CM, Romero LO, Nakagawa T, Cordero-Morales JF
Self-reported Patient Motivations for Seeking Cosmetic Procedures.
1. JAMA Dermatol - published October 1, 2018
2. Maisel A, Waldman A, Furlan K, Weil A, Sacotte K, Lazaroff JM, Lin K, Aranzazu D, Avram MM, Bell A, Cartee TV, Cazzaniga A, Chapas A, Crispin MK, Croix JA, DiGiorgio CM, Dover JS, Goldberg DJ, Goldman MP, Green JB, Griffin CL, Haimovic AD, Hausauer AK, Hernandez SL, Hsu S, Ibrahim O, Jones DH, Kaufman J, Kilmer SL, Lee NY, McDaniel DH, Schlessinger J, Tanzi E, Weiss ET, Weiss RA, Wu D, Poon E, Alam M
The dynamic nature of the conserved tegument protein UL37 of herpesviruses.
1. J Biol Chem - published October 1, 2018
2. Koenigsberg AL, Heldwein EE
The Src module: an ancient scaffold in the evolution of cytoplasmic tyrosine kinases.
1. Crit Rev Biochem Mol Biol - published October 1, 2018
2. Shah NH, Amacher JF, Nocka LM, Kuriyan J
Structural Plasticity of Neurexin 1α: Implications for its Role as Synaptic Organizer.
1. J Mol Biol - published October 1, 2018
2. Liu J, Misra A, Reddy MVVVS, White MA, Ren G, Rudenko G
Reference antigen-free and antibody-free LTD-IDMS assay for influenza H7N9 vaccine in vitro potency determination.
1. Vaccine - published October 1, 2018
2. Morgenstern K, Xie Y, Palladino G, Barr JR, Settembre EC, Williams TL, Wen Y
Membrane protein structural biology in the era of single particle cryo-EM.
1. Curr Opin Struct Biol - published October 1, 2018
2. Cheng Y
Site-Specific Incorporation of a Cu²⁺ Spin Label into Proteins for Measuring Distances by Pulsed Dipolar Electron Spin Resonance Spectroscopy.
1. J Phys Chem B - published October 1, 2018
2. Merz GE, Borbat PP, Muok AR, Srivastava M, Bunck DN, Freed JH, Crane BR
Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes.
1. Nat Microbiol - published October 1, 2018
2. Howard NC, Marin ND, Ahmed M, Rosa BA, Martin J, Bambouskova M, Sergushichev A, Loginicheva E, Kurepina N, Rangel-Moreno J, Chen L, Kreiswirth BN, Klein RS, Balada-Llasat JM, Torrelles JB, Amarasinghe GK, Mitreva M, Artyomov MN, Hsu FF, Mathema B, Khader SA
T cell receptor cross-reactivity expanded by dramatic peptide-MHC adaptability.
1. Nat Chem Biol - published October 1, 2018
2. Riley TP, Hellman LM, Gee MH, Mendoza JL, Alonso JA, Foley KC, Nishimura MI, Vander Kooi CW, Garcia KC, Baker BM
A Preclinical Assessment of ⁸⁹Zr-atezolizumab Identifies a Requirement for Carrier Added Formulations Not Observed with ⁸⁹Zr-C4.
1. Bioconjug Chem - published October 1, 2018
2. Moroz A, Lee CY, Wang YH, Hsiao JC, Sevillano N, Truillet C, Craik CS, Fong L, Wang CI, Evans MJ
DRONE: Direct Tracking of DNA Cytidine Deamination and Other DNA Modifying Activities.
1. Anal Chem - published October 1, 2018
2. Sasaki T, Kudalkar SN, Bertoletti N, Anderson KS
Outer Membrane Translocon Communicates with Inner Membrane ATPase To Stop Lipopolysaccharide Transport.
1. J Am Chem Soc - published October 1, 2018
2. Xie R, Taylor RJ, Kahne D
Protein AMPylation by an Evolutionarily Conserved Pseudokinase.
1. Cell - published October 1, 2018
2. Sreelatha A, Yee SS, Lopez VA, Park BC, Kinch LN, Pilch S, Servage KA, Zhang J, Jiou J, Karasiewicz-Urbańska M, Łobocka M, Grishin NV, Orth K, Kucharczyk R, Pawłowski K, Tomchick DR, Tagliabracci VS
Elucidating a role for the cytoplasmic domain in the Mycobacterium tuberculosis mechanosensitive channel of large conductance.
1. Sci Rep - published October 1, 2018
2. Herrera N, Maksaev G, Haswell ES, Rees DC
Fast and accurate data collection for macromolecular crystallography using the JUNGFRAU detector.
1. Nat Methods - published October 1, 2018
2. Leonarski F, Redford S, Mozzanica A, Lopez-Cuenca C, Panepucci E, Nass K, Ozerov D, Vera L, Olieric V, Buntschu D, Schneider R, Tinti G, Froejdh E, Diederichs K, Bunk O, Schmitt B, Wang M
Co-opting the Lap System of Pseudomonas fluorescens To Reversibly Customize Bacterial Cell Surfaces.
1. ACS Synth Biol - published October 1, 2018
2. Smith TJ, Sondermann H, O'Toole GA
Cryo-neutron crystallographic data collection and preliminary refinement of left-handed Z-DNA d(CGCGCG).
1. Acta Crystallogr F Struct Biol Commun - published October 1, 2018
2. Harp JM, Coates L, Sullivan B, Egli M
Calibration of rotation axes for multi-axis goniometers in macromolecular crystallography.
1. J Appl Crystallogr - published October 1, 2018
2. White KI, Bugris V, McCarthy AA, Ravelli RBG, Csankó K, Cassetta A, Brockhauser S
Structural basis for σ₁ receptor ligand recognition.
1. Nat Struct Mol Biol - published October 1, 2018
2. Schmidt HR, Betz RM, Dror RO, Kruse AC
ANKRD9 is associated with tumor suppression as a substrate receptor subunit of ubiquitin ligase.
1. Biochim Biophys Acta Mol Basis Dis - published October 1, 2018
2. Lee Y, Lim B, Lee SW, Lee WR, Kim YI, Kim M, Ju H, Kim MY, Kang SJ, Song JJ, Lee JE, Kang C
Probing the mechanisms of extracellular vesicle biogenesis and function in cancer.
1. Biochem Soc Trans - published October 1, 2018
2. Latifkar A, Cerione RA, Antonyak MA
Interaction of the Warsaw breakage syndrome DNA helicase DDX11 with the replication fork-protection factor Timeless promotes sister chromatid cohesion.
1. PLoS Genet - published October 1, 2018
2. Cortone G, Zheng G, Pensieri P, Chiappetta V, Tatè R, Malacaria E, Pichierri P, Yu H, Pisani FM
The role of small-angle scattering in structure-based screening applications.
1. Biophys Rev - published October 1, 2018
2. Chen PC, Hennig J
A Viral Protein Restricts Drosophila RNAi Immunity by Regulating Argonaute Activity and Stability.
1. Cell Host Microbe - published October 1, 2018
2. Nayak A, Kim DY, Trnka MJ, Kerr CH, Lidsky PV, Stanley DJ, Rivera BM, Li KH, Burlingame AL, Jan E, Frydman J, Gross JD, Andino R
Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor.
1. Blood - published October 1, 2018
2. Xu ER, von Bülow S, Chen PC, Lenting PJ, Kolšek K, Aponte-Santamaría C, Simon B, Foot J, Obser T, Schneppenheim R, Gräter F, Denis CV, Wilmanns M, Hennig J
Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion.
1. Cell Host Microbe - published October 1, 2018
2. Wang H, Barnes CO, Yang Z, Nussenzweig MC, Bjorkman PJ
A polymorphic residue that attenuates the antiviral potential of interferon lambda 4 in hominid lineages.
1. PLoS Pathog - published October 1, 2018
2. Bamford CGG, Aranday-Cortes E, Filipe IC, Sukumar S, Mair D, Filipe ADS, Mendoza JL, Garcia KC, Fan S, Tishkoff SA, McLauchlan J
Calcium-dependent electrostatic control of anion access to the pore of the calcium-activated chloride channel TMEM16A.
1. Elife - published October 1, 2018
2. Lam AKM, Dutzler R
Maturing <i>Mycobacterium smegmatis</i> peptidoglycan requires non-canonical crosslinks to maintain shape.
1. Elife - published October 1, 2018
2. Baranowski C, Welsh MA, Sham LT, Eskandarian HA, Lim HC, Kieser KJ, Wagner JC, McKinney J, Fantner GE, Ioerger TR, Walker S, Bernhardt TG, Rubin EJ, Rego EH
Transcription factor dimerization activates the p300 acetyltransferase.
1. Nature - published October 1, 2018
2. Ortega E, Rengachari S, Ibrahim Z, Hoghoughi N, Gaucher J, Holehouse AS, Khochbin S, Panne D
A pathway-directed screen for inhibitors of the bacterial cell elongation machinery.
1. Antimicrob Agents Chemother - published October 1, 2018
2. Buss JA, Baidin V, Welsh MA, Flores-Kim J, Cho H, Wood BM, Uehara T, Walker S, Kahne D, Bernhardt TG
HIV-1 Tat interactions with cellular 7SK and viral TAR RNAs identifies dual structural mimicry.
1. Nat Commun - published October 1, 2018
2. Pham VV, Salguero C, Khan SN, Meagher JL, Brown WC, Humbert N, de Rocquigny H, Smith JL, D'Souza VM
In silico Screening and Evaluation of Plasmodium falciparum Protein Kinase 5 (PK5) Inhibitors.
1. ChemMedChem - published October 1, 2018
2. Eubanks AL, Perkins MM, Sylvester K, Ganley JG, Posfai D, Sanschargrin PC, Hong J, Sliz P, Derbyshire ER
LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration.
1. Nature - published October 1, 2018
2. Deng M, Gui X, Kim J, Xie L, Chen W, Li Z, He L, Chen Y, Chen H, Luo W, Lu Z, Xie J, Churchill H, Xu Y, Zhou Z, Wu G, Yu C, John S, Hirayasu K, Nguyen N, Liu X, Huang F, Li L, Deng H, Tang H, Sadek AH, Zhang L, Huang T, Zou Y, Chen B, Zhu H, Arase H, Xia N, Jiang Y, Collins R, You MJ, Homsi J, Unni N, Lewis C, Chen GQ, Fu YX, Liao XC, An Z, Zheng J, Zhang N, Zhang CC
Secreted venom allergen-like proteins of helminths: Conserved modulators of host responses in animals and plants.
1. PLoS Pathog - published October 1, 2018
2. Wilbers RHP, Schneiter R, Holterman MHM, Drurey C, Smant G, Asojo OA, Maizels RM, Lozano-Torres JL
Chen et al. reply.
1. Nature - published October 1, 2018
2. Chen W, OuYang B, Chou JJ
Integrin αvβ8-expressing tumor cells evade host immunity by regulating TGF-β activation in immune cells.
1. JCI Insight - published October 1, 2018
2. Takasaka N, Seed RI, Cormier A, Bondesson AJ, Lou J, Elattma A, Ito S, Yanagisawa H, Hashimoto M, Ma R, Levine MD, Publicover J, Potts R, Jespersen JM, Campbell MG, Conrad F, Marks JD, Cheng Y, Baron JL, Nishimura SL
Cryo-EM structure of the Ebola virus nucleoprotein-RNA complex at 3.6 Å resolution.
1. Nature - published October 1, 2018
2. Sugita Y, Matsunami H, Kawaoka Y, Noda T, Wolf M
A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery.
1. PLoS Genet - published October 1, 2018
2. Rohs PDA, Buss J, Sim SI, Squyres GR, Srisuknimit V, Smith M, Cho H, Sjodt M, Kruse AC, Garner EC, Walker S, Kahne DE, Bernhardt TG
Flipping ATP to AMPlify Kinase Functions.
1. Cell - published October 1, 2018
2. Sheetz JB, Lemmon MA
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes.
1. Science - published October 1, 2018
2. Harrington LB, Burstein D, Chen JS, Paez-Espino D, Ma E, Witte IP, Cofsky JC, Kyrpides NC, Banfield JF, Doudna JA
Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity.
1. Protein Sci - published October 1, 2018
2. Grell TAJ, Bell BN, Nguyen C, Dowling DP, Bruender NA, Bandarian V, Drennan CL
A Comparison of QM/MM Simulations with and without the Drude Oscillator Model Based on Hydration Free Energies of Simple Solutes.
1. Molecules - published October 1, 2018
2. König G, Pickard FC, Huang J, Thiel W, MacKerell AD, Brooks BR, York DM
The potent and selective cyclin-dependent kinases 4 and 6 inhibitor ribociclib (LEE011) is a versatile combination partner in preclinical cancer models.
1. Oncotarget - published October 1, 2018
2. Kim S, Tiedt R, Loo A, Horn T, Delach S, Kovats S, Haas K, Engstler BS, Cao A, Pinzon-Ortiz M, Mulford I, Acker MG, Chopra R, Brain C, di Tomaso E, Sellers WR, Caponigro G
Advances in image processing for single-particle analysis by electron cryomicroscopy and challenges ahead.
1. Curr Opin Struct Biol - published October 1, 2018
2. Vilas JL, Tabassum N, Mota J, Maluenda D, Jiménez-Moreno A, Majtner T, Carazo JM, Acton ST, Sorzano COS