Member Publications

Jump to specific year:

110 Member Publications for July 2018

Erratum to: Characterizing Intact Macromolecular Complexes Using Native Mass Spectrometry.
1. Methods Mol Biol - published July 26, 2018
2. Boeri Erba E, Signor L, Oliva MF, Hans F, Petosa C
Rational Drug Design Using Integrative Structural Biology.
1. Methods Mol Biol - published July 25, 2018
2. Chegkazi MS, Mamais M, Sotiropoulou AI, Chrysina ED
The Molecular Mechanism of Notch Activation.
1. Adv Exp Med Biol - published July 22, 2018
2. Lovendahl KN, Blacklow SC, Gordon WR
Nuclear receptor/Wnt beta-catenin interactions are regulated via differential CBP/p300 coactivator usage.
1. PLoS One - published July 19, 2018
2. Ono M, Lai KKY, Wu K, Nguyen C, Lin DP, Murali R, Kahn M
Exchange of functional domains between a bacterial conjugative relaxase and the integrase of the human adeno-associated virus.
1. PLoS One - published July 18, 2018
2. Agúndez L, Zárate-Pérez F, Meier AF, Bardelli M, Llosa M, Escalante CR, Linden RM, Henckaerts E
Imaging Plastids in 2D and 3D: Confocal and Electron Microscopy.
1. Methods Mol Biol - published July 11, 2018
2. Flori S, Jouneau PH, Gallet B, Estrozi LF, Moriscot C, Schoehn G, Finazzi G, Falconet D
A convenient, reliable, and fast acoustic pressure field measurement method for magnetic resonance-guided high-intensity focused ultrasound systems with phased array transducers.
1. J Ther Ultrasound - published July 11, 2018
2. Kothapalli SVVN, Partanen A, Zhu L, Altman MB, Gach HM, Hallahan DE, Chen H
NSF-mediated disassembly of on and off-pathway SNARE complexes and inhibition by complexin.
1. Elife - published July 9, 2018
2. Choi UB, Zhao M, White KI, Pfuetzner RA, Esquivies L, Zhou Q, Brunger AT
Engineering ER-stress dependent non-conventional mRNA splicing.
1. Elife - published July 9, 2018
2. Li W, Okreglak V, Peschek J, Kimmig P, Zubradt M, Weissman JS, Walter P
Microtubule minus-end aster organization is driven by processive HSET-tubulin clusters.
1. Nat Commun - published July 9, 2018
2. Norris SR, Jung S, Singh P, Strothman CE, Erwin AL, Ohi MD, Zanic M, Ohi R
MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation.
1. Cancer Cell - published July 9, 2018
2. Jin L, Chun J, Pan C, Li D, Lin R, Alesi GN, Wang X, Kang HB, Song L, Wang D, Zhang G, Fan J, Boggon TJ, Zhou L, Kowalski J, Qu CK, Steuer CE, Chen GZ, Saba NF, Boise LH, Owonikoko TK, Khuri FR, Magliocca KR, Shin DM, Lonial S, Kang S
Structural Insights from HIV-Antibody Co-Evolution and Related Immunization Studies.
1. AIDS Res Hum Retroviruses - published July 7, 2018
2. Zhou JO, Ton T, Morriss JW, Nguyen D, Fera D
Structural Basis for the Selective Inhibition of c-Jun N-Terminal Kinase 1 Determined by Rigid DARPin-DARPin Fusions.
1. J Mol Biol - published July 6, 2018
2. Wu Y, Honegger A, Batyuk A, Mittl PRE, Plückthun A
Control of mRNA decapping by autoinhibition.
1. Nucleic Acids Res - published July 6, 2018
2. Paquette DR, Tibble RW, Daifuku TS, Gross JD
Hydrofluoric Acid-Based Derivatization Strategy To Profile PARP-1 ADP-Ribosylation by LC-MS/MS.
1. J Proteome Res - published July 6, 2018
2. Gagné JP, Langelier MF, Pascal JM, Poirier GG
Structure basis for RNA-guided DNA degradation by Cascade and Cas3.
1. Science - published July 6, 2018
2. Xiao Y, Luo M, Dolan AE, Liao M, Ke A
Single-Particle Reconstruction of Biological Molecules-Story in a Sample (Nobel Lecture).
1. Angew Chem Int Ed Engl - published July 6, 2018
2. Frank J
Discovery of a Highly Potent and Broadly Effective EGFR and HER2 Exon 20 Insertion Mutant Inhibitor.
1. Angew Chem Int Ed Engl - published July 6, 2018
2. Jang J, Son J, Park E, Kosaka T, Saxon JA, De Clercq D, Choi HG, Tanizaki J, Eck MJ, Jänne PA, Gray NS
Lipids surf the groove in scramblases.
1. Proc Natl Acad Sci U S A - published July 6, 2018
2. Ballesteros A, Swartz KJ
Smart urea ionic co-crystals with enhanced urease inhibition activity for improved nitrogen cycle management.
1. Chem Commun (Camb) - published July 5, 2018
2. Casali L, Mazzei L, Shemchuk O, Honer K, Grepioni F, Ciurli S, Braga D, Baltrusaitis J
Discovery of Mcl-1 inhibitors from integrated high throughput and virtual screening.
1. Sci Rep - published July 5, 2018
2. Mady ASA, Liao C, Bajwa N, Kump KJ, Abulwerdi FA, Lev KL, Miao L, Grigsby SM, Perdih A, Stuckey JA, Du Y, Fu H, Nikolovska-Coleska Z
Characterization of Glycoproteins with the Immunoglobulin Fold by X-Ray Crystallography and Biophysical Techniques.
1. J Vis Exp - published July 5, 2018
2. Ereño-Orbea J, Sicard T, Cui H, Akula I, Julien JP
Investigating the Mechanism of Horseradish Peroxidase as a RAFT-Initiase.
1. Polymers (Basel) - published July 5, 2018
2. Danielson AP, Van-Kuren DB, Bornstein JP, Kozuszek CT, Berberich JA, Page RC, Konkolewicz D
microRNA-122 amplifies hepatitis C virus translation by shaping the structure of the internal ribosomal entry site.
1. Nat Commun - published July 4, 2018
2. Schult P, Roth H, Adams RL, Mas C, Imbert L, Orlik C, Ruggieri A, Pyle AM, Lohmann V
A Hyperthermophilic Phage Decoration Protein Suggests Common Evolutionary Origin with Herpesvirus Triplex Proteins and an Anti-CRISPR Protein.
1. Structure - published July 3, 2018
2. Stone NP, Hilbert BJ, Hidalgo D, Halloran KT, Lee J, Sontheimer EJ, Kelch BA
Structural Plasticity in the C-Terminal Region of Macrophage Migration Inhibitory Factor-2 Is Associated with an Induced Fit Mechanism for a Selective Inhibitor.
1. Biochemistry - published July 3, 2018
2. Pantouris G, Bucala R, Lolis EJ
Separating the effects of nucleotide and EB binding on microtubule structure.
1. Proc Natl Acad Sci U S A - published July 3, 2018
2. Zhang R, LaFrance B, Nogales E
Development of Endocyclic Control Elements for Peptide Macrocycles.
1. J Am Chem Soc - published July 3, 2018
2. Appavoo SD, Kaji T, Frost JR, Scully CCG, Yudin AK
Pharmacological evaluation of new constituents of "Spice": synthetic cannabinoids based on indole, indazole, benzimidazole and carbazole scaffolds.
1. Forensic Toxicol - published July 3, 2018
2. Schoeder CT, Hess C, Madea B, Meiler J, Müller CE
The N-terminal region of photocleavable peptides that bind HLA-DR1 determines the kinetics of fragment release.
1. PLoS One - published July 3, 2018
2. Negroni MP, Stern LJ
Understanding the Species Selectivity of Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors.
1. Biochemistry - published July 3, 2018
2. Zhao B, Arnold AL, Coronel MA, Lee JH, Lee T, Olejniczak ET, Fesik SW
Deep mutational analysis reveals functional trade-offs in the sequences of EGFR autophosphorylation sites.
1. Proc Natl Acad Sci U S A - published July 3, 2018
2. Cantor AJ, Shah NH, Kuriyan J
Serotonin uptake is required for Rac1 activation in Kras-induced acinar-to-ductal metaplasia in the pancreas.
1. J Pathol - published July 3, 2018
2. Saponara E, Visentin M, Baschieri F, Seleznik G, Martinelli P, Esposito I, Buschmann J, Chen R, Parrotta R, Borgeaud N, Bombardo M, Malagola E, Caflisch A, Farhan H, Graf R, Sonda S
Amine hemilability enables boron to mechanistically resemble either hydride or proton.
1. Nat Chem - published July 3, 2018
2. Lee CF, Diaz DB, Holownia A, Kaldas SJ, Liew SK, Garrett GE, Dudding T, Yudin AK
DNA Repair Deficient Chinese Hamster Ovary Cells Exhibiting Differential Sensitivity to Charged Particle Radiation under Aerobic and Hypoxic Conditions.
1. Int J Mol Sci - published July 3, 2018
2. Cartwright IM, Su C, Haskins JS, Salinas VA, Sunada S, Yu H, Uesaka M, Hirakawa H, Chen DJ, Fujimori A, Kato TA
An Aspartate-Specific Solute-Binding Protein Regulates Protein Kinase G Activity To Control Glutamate Metabolism in Mycobacteria.
1. mBio - published July 3, 2018
2. Bhattacharyya N, Nkumama IN, Newland-Smith Z, Lin LY, Yin W, Cullen RE, Griffiths JS, Jarvis AR, Price MJ, Chong PY, Wallis R, O'Hare HM
Islet-Derived eATP Fuels Autoreactive CD8+ Cells and Facilitates the Onset of Type 1 Diabetes.
1. Diabetes - published July 3, 2018
2. Tezza S, Ben Nasr M, D'Addio F, Vergani A, Usuelli V, Falzoni S, Bassi R, Dellepiane S, Fotino C, Rossi C, Maestroni A, Solini A, Corradi D, Giani E, Mameli C, Bertuzzi F, Pezzolesi MG, Wasserfall CH, Atkinson MA, Füchtbauer EM, Ricordi C, Folli F, Di Virgilio F, Pileggi A, Dhe-Paganon S, Zuccotti GV, Fiorina P
Is It Possible to Develop a "Universal" Influenza Virus Vaccine? Potential for a Universal Influenza Vaccine.
1. Cold Spring Harb Perspect Biol - published July 2, 2018
2. Crowe JE Jr
Peptide-Programmable Nanoparticle Superstructures with Tailored Electrocatalytic Activity.
1. ACS Nano - published July 2, 2018
2. Kang ES, Kim YT, Ko YS, Kim NH, Cho G, Huh YH, Kim JH, Nam J, Thach TT, Youn D, Kim YD, Yun WS, DeGrado WF, Kim SY, Hammond PT, Lee J, Kwon YU, Ha DH, Kim YH
Analysis of a vinculin homolog in a sponge (phylum Porifera) reveals that vertebrate-like cell adhesions emerged early in animal evolution.
1. J Biol Chem - published July 2, 2018
2. Miller PW, Pokutta S, Mitchell JM, Chodaparambil JV, Clarke DN, Nelson WJ, Weis WI, Nichols SA
Solid State NMR Studies of Intact Lipopolysaccharide Endotoxin.
1. ACS Chem Biol - published July 2, 2018
2. Laguri C, Silipo A, Martorana AM, Schanda P, Marchetti R, Polissi A, Molinaro A, Simorre JP
Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4.
1. Nat Struct Mol Biol - published July 2, 2018
2. Bodnar NO, Kim KH, Ji Z, Wales TE, Svetlov V, Nudler E, Engen JR, Walz T, Rapoport TA
Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance.
1. Biol Open - published July 2, 2018
2. Mavor D, Barlow KA, Asarnow D, Birman Y, Britain D, Chen W, Green EM, Kenner LR, Mensa B, Morinishi LS, Nelson CA, Poss EM, Suresh P, Tian R, Arhar T, Ary BE, Bauer DP, Bergman ID, Brunetti RM, Chio CM, Dai SA, Dickinson MS, Elledge SK, Helsell CVM, Hendel NL, Kang E, Kern N, Khoroshkin MS, Kirkemo LL, Lewis GR, Lou K, Marin WM, Maxwell AM, McTigue PF, Myers-Turnbull D, Nagy TL, Natale AM, Oltion K, Pourmal S, Reder GK, Rettko NJ, Rohweder PJ, Schwarz DMC, Tan SK, Thomas PV, Tibble RW, Town JP, Tsai MK, Ugur FS, Wassarman DR, Wolff AM, Wu TS, Bogdanoff D, Li J, Thorn KS, O'Conchúir S, Swaney DL, Chow ED, Madhani HD, Redding S, Bolon DN, Kortemme T, DeRisi JL, Kampmann M, Fraser JS
Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent CRL4CRBN activity.
1. Blood - published July 2, 2018
2. Sievers QL, Gasser JA, Cowley GS, Fischer ES, Ebert BL
The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles.
1. Cell Rep - published July 2, 2018
2. Coulter ME, Dorobantu CM, Lodewijk GA, Delalande F, Cianferani S, Ganesh VS, Smith RS, Lim ET, Xu CS, Pang S, Wong ET, Lidov HGW, Calicchio ML, Yang E, Gonzalez DM, Schlaeger TM, Mochida GH, Hess H, Lee WA, Lehtinen MK, Kirchhausen T, Haussler D, Jacobs FMJ, Gaudin R, Walsh CA
Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes.
1. Cell Rep - published July 2, 2018
2. Edwards MR, Liu H, Shabman RS, Ginell GM, Luthra P, Ramanan P, Keefe LJ, Köllner B, Amarasinghe GK, Taylor DJ, Leung DW, Basler CF
Conformational Switching of the Nuclear Exosome during Ribosome Biogenesis.
1. Biochemistry - published July 2, 2018
2. Kummer E, Ban N
RNA Binding and HEPN-Nuclease Activation Are Decoupled in CRISPR-Cas13a.
1. Cell Rep - published July 2, 2018
2. Tambe A, East-Seletsky A, Knott GJ, Doudna JA, O'Connell MR
The RUNX1/IL-34/CSF-1R axis is an autocrinally regulated modulator of resistance to BRAF-V600E inhibition in melanoma.
1. JCI Insight - published July 2, 2018
2. Giricz O, Mo Y, Dahlman KB, Cotto-Rios XM, Vardabasso C, Nguyen H, Matusow B, Bartenstein M, Polishchuk V, Johnson DB, Bhagat TD, Shellooe R, Burton E, Tsai J, Zhang C, Habets G, Greally JM, Yu Y, Kenny PA, Fields GB, Pradhan K, Stanley ER, Bernstein E, Bollag G, Gavathiotis E, West BL, Sosman JA, Verma AK
From proteomics to discovery of first-in-class ST2 inhibitors active in vivo.
1. JCI Insight - published July 2, 2018
2. Ramadan AM, Daguindau E, Rech JC, Chinnaswamy K, Zhang J, Hura GL, Griesenauer B, Bolten Z, Robida A, Larsen M, Stuckey JA, Yang CY, Paczesny S
Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in TP53 wild-type Ewing sarcoma.
1. J Exp Med - published July 2, 2018
2. Stolte B, Iniguez AB, Dharia NV, Robichaud AL, Conway AS, Morgan AM, Alexe G, Schauer NJ, Liu X, Bird GH, Tsherniak A, Vazquez F, Buhrlage SJ, Walensky LD, Stegmaier K
Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.
1. Cell - published July 2, 2018
2. Sibener LV, Fernandes RA, Kolawole EM, Carbone CB, Liu F, McAffee D, Birnbaum ME, Yang X, Su LF, Yu W, Dong S, Gee MH, Jude KM, Davis MM, Groves JT, Goddard WA 3rd, Heath JR, Evavold BD, Vale RD, Garcia KC
Etomidate and Etomidate Analog Binding and Positive Modulation of γ-Aminobutyric Acid Type A Receptors: Evidence for a State-dependent Cutoff Effect.
1. Anesthesiology - published July 2, 2018
2. McGrath M, Yu Z, Jayakar SS, Ma C, Tolia M, Zhou X, Miller KW, Cohen JB, Raines DE
Quantitative Profiling of the Lymph Node Clearance Capacity.
1. Sci Rep - published July 2, 2018
2. Clement CC, Wang W, Dzieciatkowska M, Cortese M, Hansen KC, Becerra A, Thangaswamy S, Nizamutdinova I, Moon JY, Stern LJ, Gashev AA, Zawieja D, Santambrogio L
Intra-seasonal antibody repertoire analysis of a subject immunized with an MF59®-adjuvanted pandemic 2009 H1N1 vaccine.
1. Vaccine - published July 2, 2018
2. Ferdman J, Palladino G, Liao HX, Moody MA, Kepler TB, Del Giudice G, Dormitzer PR, Harrison SC, Settembre EC, Suphaphiphat P
Mechanotransduction by PCDH15 Relies on a Novel cis-Dimeric Architecture.
1. Neuron - published July 2, 2018
2. Dionne G, Qiu X, Rapp M, Liang X, Zhao B, Peng G, Katsamba PS, Ahlsen G, Rubinstein R, Potter CS, Carragher B, Honig B, Müller U, Shapiro L
Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module.
1. Cell - published July 2, 2018
2. Hsu PL, Li H, Lau HT, Leonen C, Dhall A, Ong SE, Chatterjee C, Zheng N
Molecular Basis of Unusually High Neutralization Resistance in Tier 3 HIV-1 Strain 253-11.
1. J Virol - published July 1, 2018
2. Moyo T, Ereño-Orbea J, Jacob RA, Pavillet CE, Kariuki SM, Tangie EN, Julien JP, Dorfman JR
Detecting Protein-Glycolipid Interactions Using CaR-ESI-MS and Model Membranes: Comparison of Pre-loaded and Passively Loaded Picodiscs.
1. J Am Soc Mass Spectrom - published July 1, 2018
2. Li J, Han L, Li J, Kitova EN, Xiong ZJ, Privé GG, Klassen JS
Structural elements of stromal interaction molecule function.
1. Cell Calcium - published July 1, 2018
2. Novello MJ, Zhu J, Feng Q, Ikura M, Stathopulos PB
Publisher Correction: The cytoplasmic dynein transport machinery and its many cargoes.
1. Nat Rev Mol Cell Biol - published July 1, 2018
2. Reck-Peterson SL, Redwine WB, Vale RD, Carter AP
Uniparental disomy unveils a novel recessive mutation in POMT2.
1. Neuromuscul Disord - published July 1, 2018
2. Brun BN, Willer T, Darbro BW, Gonorazky HD, Naumenko S, Dowling JJ, Campbell KP, Moore SA, Mathews KD
Inhibitors of the HIV-1 capsid, a target of opportunity.
1. Curr Opin HIV AIDS - published July 1, 2018
2. Carnes SK, Sheehan JH, Aiken C
Structural Basis of Smoothened Activation in Hedgehog Signaling.
1. Cell - published July 1, 2018
2. Huang P, Zheng S, Wierbowski BM, Kim Y, Nedelcu D, Aravena L, Liu J, Kruse AC, Salic A
Structure of a Thyrotropin Receptor Monoclonal Antibody Variable Region Provides Insight into Potential Mechanisms for its Inverse Agonist Activity.
1. Thyroid - published July 1, 2018
2. Chen CR, McLachlan SM, Hubbard PA, McNally R, Murali R, Rapoport B
Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling.
1. J Med Chem - published July 1, 2018
2. Abbott JR, Hodges TR, Daniels RN, Patel PA, Kennedy JP, Howes JE, Akan DT, Burns MC, Sai J, Sobolik T, Beesetty Y, Lee T, Rossanese OW, Phan J, Waterson AG, Fesik SW
Interactions of a Bacterial Cu(I)-ATPase with a Complex Lipid Environment.
1. Biochemistry - published July 1, 2018
2. Autzen HE, Koldsø H, Stansfeld PJ, Gourdon P, Sansom MSP, Nissen P
Sterol 14α-Demethylase Structure-Based Design of VNI (( R)- N-(1-(2,4-Dichlorophenyl)-2-(1 H-imidazol-1-yl)ethyl)-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide)) Derivatives To Target Fungal Infections: Synthesis, Biological Evaluation, and Crystallographic Analysis.
1. J Med Chem - published July 1, 2018
2. Friggeri L, Hargrove TY, Wawrzak Z, Blobaum AL, Rachakonda G, Lindsley CW, Villalta F, Nes WD, Botta M, Guengerich FP, Lepesheva GI
Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT.
1. Nat Immunol - published July 1, 2018
2. Lo WL, Shah NH, Ahsan N, Horkova V, Stepanek O, Salomon AR, Kuriyan J, Weiss A
CAPTURE: In Situ Analysis of Chromatin Composition of Endogenous Genomic Loci by Biotinylated dCas9.
1. Curr Protoc Mol Biol - published July 1, 2018
2. Liu X, Zhang Y, Chen Y, Li M, Shao Z, Zhang MQ, Xu J
Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection.
1. Trends Cancer - published July 1, 2018
2. Huang CH, Lee KC, Doudna JA
Disorder at the Tips of a Disease-Relevant Aβ42 Amyloid Fibril: A Molecular Dynamics Study.
1. J Phys Chem B - published July 1, 2018
2. Ilie IM, Caflisch A
SIMBAD: a sequence-independent molecular-replacement pipeline.
1. Acta Crystallogr D Struct Biol - published July 1, 2018
2. Simpkin AJ, Simkovic F, Thomas JMH, Savko M, Lebedev A, Uski V, Ballard C, Wojdyr M, Wu R, Sanishvili R, Xu Y, Lisa MN, Buschiazzo A, Shepard W, Rigden DJ, Keegan RM
A Mechanistic Model for the Aziridine Aldehyde-Driven Macrocyclization of Peptides.
1. J Org Chem - published July 1, 2018
2. Belding L, Zaretsky S, Yudin AK, Dudding T
Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV.
1. PLoS Pathog - published July 1, 2018
2. Dingens AS, Acharya P, Haddox HK, Rawi R, Xu K, Chuang GY, Wei H, Zhang B, Mascola JR, Carragher B, Potter CS, Overbaugh J, Kwong PD, Bloom JD
ID30B - a versatile beamline for macromolecular crystallography experiments at the ESRF.
1. J Synchrotron Radiat - published July 1, 2018
2. McCarthy AA, Barrett R, Beteva A, Caserotto H, Dobias F, Felisaz F, Giraud T, Guijarro M, Janocha R, Khadrouche A, Lentini M, Leonard GA, Lopez Marrero M, Malbet-Monaco S, McSweeney S, Nurizzo D, Papp G, Rossi C, Sinoir J, Sorez C, Surr J, Svensson O, Zander U, Cipriani F, Theveneau P, Mueller-Dieckmann C
Stem cell heterogeneity drives the parasitic life cycle of Schistosoma mansoni.
1. Elife - published July 1, 2018
2. Wang B, Lee J, Li P, Saberi A, Yang H, Liu C, Zhao M, Newmark PA
Inert and seed-competent tau monomers suggest structural origins of aggregation.
1. Elife - published July 1, 2018
2. Mirbaha H, Chen D, Morazova OA, Ruff KM, Sharma AM, Liu X, Goodarzi M, Pappu RV, Colby DW, Mirzaei H, Joachimiak LA, Diamond MI
Author Correction: Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding.
1. Nat Commun - published July 1, 2018
2. Guo HF, Tsai CL, Terajima M, Tan X, Banerjee P, Miller MD, Liu X, Yu J, Byemerwa J, Alvarado S, Kaoud TS, Dalby KN, Bota-Rabassedas N, Chen Y, Yamauchi M, Tainer JA, Phillips GN Jr, Kurie JM
PtdIns(4,5)P₂ stabilizes active states of GPCRs and enhances selectivity of G-protein coupling.
1. Nature - published July 1, 2018
2. Yen HY, Hoi KK, Liko I, Hedger G, Horrell MR, Song W, Wu D, Heine P, Warne T, Lee Y, Carpenter B, Plückthun A, Tate CG, Sansom MSP, Robinson CV
Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
1. Cell Rep - published July 1, 2018
2. Liu Y, Esyunina D, Olovnikov I, Teplova M, Kulbachinskiy A, Aravin AA, Patel DJ
Ligand-Mediated Biofilm Formation via Enhanced Physical Interaction between a Diguanylate Cyclase and Its Receptor.
1. MBio - published July 1, 2018
2. Giacalone D, Smith TJ, Collins AJ, Sondermann H, Koziol LJ, O'Toole GA
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes.
1. Elife - published July 1, 2018
2. Sorger PK, Lin JR, Izar B, Wang S, Yapp C, Mei S, Shah PM, Santagata S
Cryo-EM structure of a fungal mitochondrial calcium uniporter.
1. Nature - published July 1, 2018
2. Nguyen NX, Armache JP, Lee C, Yang Y, Zeng W, Mootha VK, Cheng Y, Bai XC, Jiang Y
Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters.
1. Nature - published July 1, 2018
2. Baradaran R, Wang C, Siliciano AF, Long SB
Evolution of a central neural circuit underlies Drosophila mate preferences.
1. Nature - published July 1, 2018
2. Seeholzer LF, Seppo M, Stern DL, Ruta V
X-ray and cryo-EM structures of the mitochondrial calcium uniporter.
1. Nature - published July 1, 2018
2. Fan C, Fan M, Orlando BJ, Fastman NM, Zhang J, Xu Y, Chambers MG, Xu X, Perry K, Liao M, Feng L
Prespliceosome structure provides insights into spliceosome assembly and regulation.
1. Nature - published July 1, 2018
2. Plaschka C, Lin PC, Charenton C, Nagai K
Development of Ahmedabad's Air Information and Response (AIR) Plan to Protect Public Health.
1. Int J Environ Res Public Health - published July 1, 2018
2. Limaye VS, Knowlton K, Sarkar S, Ganguly PS, Pingle S, Dutta P, M SL, Tiwari A, Solanki B, Shah C, Raval G, Kakkad K, Beig G, Parkhi N, Jaiswal A, Mavalankar D
How small-molecule inhibitors of dengue-virus infection interfere with viral membrane fusion.
1. Elife - published July 1, 2018
2. Chao LH, Jang J, Johnson A, Nguyen A, Gray N, Yang PL, Harrison SC
Identification of ions in experimental electrostatic potential maps.
1. IUCrJ - published July 1, 2018
2. Wang J, Liu Z, Frank J, Moore PB
Calprotectin protects against experimental colonic inflammation in mice.
1. Br J Pharmacol - published July 1, 2018
2. Aranda CJ, Ocón B, Arredondo-Amador M, Suárez MD, Zarzuelo A, Chazin WJ, Martínez-Augustin O, de Medina FS
MR1 displays the microbial metabolome driving selective MR1-restricted T cell receptor usage.
1. Sci Immunol - published July 1, 2018
2. Harriff MJ, McMurtrey C, Froyd CA, Jin H, Cansler M, Null M, Worley A, Meermeier EW, Swarbrick G, Nilsen A, Lewinsohn DA, Hildebrand W, Adams EJ, Lewinsohn DM
Sustainable Syntheses of (-)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site.
1. Sci Rep - published July 1, 2018
2. Smedley CJ, Stanley PA, Qazzaz ME, Prota AE, Olieric N, Collins H, Eastman H, Barrow AS, Lim KH, Kam TS, Smith BJ, Duivenvoorden HM, Parker BS, Bradshaw TD, Steinmetz MO, Moses JE
Molecular model of J-aggregated pseudoisocyanine fibers.
1. J Chem Phys - published July 1, 2018
2. Bricker WP, Banal JL, Stone MB, Bathe M
Structure of the Human cGAS-DNA Complex Reveals Enhanced Control of Immune Surveillance.
1. Cell - published July 1, 2018
2. Zhou W, Whiteley AT, de Oliveira Mann CC, Morehouse BR, Nowak RP, Fischer ES, Gray NS, Mekalanos JJ, Kranzusch PJ
P2X7R mutation disrupts the NLRP3-mediated Th program and predicts poor cardiac allograft outcomes.
1. J Clin Invest - published July 1, 2018
2. D'Addio F, Vergani A, Potena L, Maestroni A, Usuelli V, Ben Nasr M, Bassi R, Tezza S, Dellepiane S, El Essawy B, Iascone M, Iacovoni A, Borgese L, Liu K, Visner G, Dhe-Paganon S, Corradi D, Abdi R, Starling RC, Folli F, Zuccotti GV, Sayegh MH, Heeger PS, Chandraker A, Grigioni F, Fiorina P
Metalloenzymes in natural product biosynthetic pathways.
1. Nat Prod Rep - published July 1, 2018
2. Ryan KS, Drennan CL
Mass spectrometry quantitation of proteins from small pools of developing auditory and vestibular cells.
1. Sci Data - published July 1, 2018
2. Krey JF, Scheffer DI, Choi D, Reddy A, David LL, Corey DP, Barr-Gillespie PG
Determination of the binding affinities of Neisseria meningitidis serogroup W capsule polymerase with two nucleotide sugar substrates.
1. BMC Res Notes - published July 1, 2018
2. Sharyan A, Gonzalez C, Ukaegbu O, Powell K, McCarthy PC
Coherent feedforward regulation of gene expression by Caulobacter σT and GsrN during hyperosmotic stress.
1. J Bacteriol - published July 1, 2018
2. Tien MZ, Stein BJ, Crosson S
Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin.
1. Sci Rep - published July 1, 2018
2. Debela M, Magdolen V, Skala W, Elsässer B, Schneider EL, Craik CS, Biniossek ML, Schilling O, Bode W, Brandstetter H, Goettig P
Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation.
1. MBio - published July 1, 2018
2. Klein RD, Shu Q, Cusumano ZT, Nagamatsu K, Gualberto NC, Lynch AJL, Wu C, Wang W, Jain N, Pinkner JS, Amarasinghe GK, Hultgren SJ, Frieden C, Chapman MR
A simple and robust procedure for preparing graphene-oxide cryo-EM grids.
1. J Struct Biol - published July 1, 2018
2. Palovcak E, Wang F, Zheng SQ, Yu Z, Li S, Betegon M, Bulkley D, Agard DA, Cheng Y
SOSIP changes affect human immunodeficiency virus (HIV-1) envelope glycoprotein conformation and CD4 engagement.
1. J Virol - published July 1, 2018
2. Alsahafi N, Anand SP, Castillo-Menendez L, Verly MM, Medjahed H, Prévost J, Herschhorn A, Richard J, Schön A, Melillo B, Freire E, Smith AB 3rd, Sodroski J, Finzi A
Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro.
1. Proc Natl Acad Sci U S A - published July 1, 2018
2. Gee MH, Sibener LV, Birnbaum ME, Jude KM, Yang X, Fernandes RA, Mendoza JL, Glassman CR, Garcia KC
Structure of the replication regulator Sap1 reveals functionally important interfaces.
1. Sci Rep - published July 1, 2018
2. Jørgensen MM, Ekundayo B, Zaratiegui M, Skriver K, Thon G, Schalch T
Quinoxaline-Based Linear HCV NS3/4A Protease Inhibitors Exhibit Potent Activity against Drug Resistant Variants.
1. ACS Med Chem Lett - published July 1, 2018
2. Rusere LN, Matthew AN, Lockbaum GJ, Jahangir M, Newton A, Petropoulos CJ, Huang W, Kurt Yilmaz N, Schiffer CA, Ali A
Human β-defensin 2 kills Candida albicans through phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization.
1. Sci Adv - published July 1, 2018
2. Järvå M, Phan TK, Lay FT, Caria S, Kvansakul M, Hulett MD
Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons.
1. Nat Biomed Eng - published July 1, 2018
2. Tekin H, Simmons S, Cummings B, Gao L, Adiconis X, Hession CC, Ghoshal A, Dionne D, Choudhury SR, Yesilyurt V, Sanjana NE, Shi X, Lu C, Heidenreich M, Pan JQ, Levin JZ, Zhang F