Member Publications

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127 Member Publications for September 2015

Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles.
1. PLoS Genet - published September 30, 2015
2. Chang H, Cahill H, Smallwood PM, Wang Y, Nathans J
Crystal structure of halogenase PltA from the pyoluteorin biosynthetic pathway.
1. J. Struct. Biol. - published September 30, 2015
2. Pang AH, Garneau-Tsodikova S, Tsodikov OV
Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
1. Proc. Natl. Acad. Sci. U.S.A. - published September 29, 2015
2. Lohman JR, Ma M, Osipiuk J, Nocek B, Kim Y, Chang C, Cuff M, Mack J, Bigelow L, Li H, Endres M, Babnigg G, Joachimiak A, Phillips GN, Shen B
Multitargeting of selected prostanoid receptors provides agents with enhanced anti-inflammatory activity in macrophages.
1. FASEB J. - published September 29, 2015
2. Wang JW, Woodward DF, Martos JL, Cornell CL, Carling RW, Kingsley PJ, Marnett LJ
Helicases in Antiviral Immunity: Dual Properties as Sensors and Effectors.
1. Trends Biochem. Sci. - published September 28, 2015
2. Ahmad S, Hur S
Crystal structure of the Varkud satellite ribozyme.
1. Nat. Chem. Biol. - published September 28, 2015
2. Suslov NB, DasGupta S, Huang H, Fuller JR, Lilley DM, Rice PA, Piccirilli JA
Different therapeutic outcomes of benznidazole and VNI treatment in distinct genders of mouse experimental models of Trypanosoma cruzi infection.
1. Antimicrob. Agents Chemother. - published September 28, 2015
2. Guedes-da-Silva FH, Batista DG, da Silva CF, Meuser MB, Simões-Silva MR, de Araújo JS, Ferreira CG, Moreira OC, Britto C, Lepesheva GI, Soeiro Mde N
Structural basis for gene regulation by a B12-dependent photoreceptor.
1. Nature - published September 28, 2015
2. Jost M, Fernández-Zapata J, Polanco MC, Ortiz-Guerrero JM, Chen PY, Kang G, Padmanabhan S, Elías-Arnanz M, Drennan CL
Reevaluating αE-catenin monomer and homodimer functions by characterizing E-cadherin/αE-catenin chimeras.
1. J. Cell Biol. - published September 28, 2015
2. Bianchini JM, Kitt KN, Gloerich M, Pokutta S, Weis WI, Nelson WJ
Updates to the Integrated Protein-Protein Interaction Benchmarks: Docking Benchmark Version 5 and Affinity Benchmark Version 2.
1. J. Mol. Biol. - published September 25, 2015
2. Vreven T, Moal IH, Vangone A, Pierce BG, Kastritis PL, Torchala M, Chaleil R, Jiménez-García B, Bates PA, Fernandez-Recio J, Bonvin AM, Weng Z
Highly multiplexed imaging of single cells using a high-throughput cyclic immunofluorescence method.
1. Nat Commun - published September 25, 2015
2. Lin JR, Fallahi-Sichani M, Sorger PK
A Molecular Toolkit to Visualize Native Protein Assemblies in the Context of Human Disease.
1. Sci Rep - published September 24, 2015
2. Gilmore BL, Winton CE, Demmert AC, Tanner JR, Bowman S, Karageorge V, Patel K, Sheng Z, Kelly DF
Molecular architecture of the yeast Mediator complex.
1. Elife - published September 24, 2015
2. Robinson PJ, Trnka MJ, Pellarin R, Greenberg CH, Bushnell DA, Davis R, Burlingame AL, Sali A, Kornberg RD
NMR studies reveal a novel grab and release mechanism for efficient catalysis of the bacterial 2-Cys peroxiredoxin machinery.
1. FEBS J. - published September 24, 2015
2. Nartey W, Basak S, Kamariah N, Manimekalai MS, Robson S, Wagner G, Eisenhaber B, Eisenhaber F, Grüber G
Design of the DOVE (Determining Effects of Platelet Inhibition on Vaso-Occlusive Events) trial: A global Phase 3 double-blind, randomized, placebo-controlled, multicenter study of the efficacy and safety of prasugrel in pediatric patients with sickle cell anemia utilizing a dose titration strategy.
1. Pediatr Blood Cancer - published September 24, 2015
2. Hoppe CC, Styles L, Heath LE, Zhou C, Jakubowski JA, Winters KJ, Brown PB, Rees DC, Heeney MM
Involvement of VAT-1 in phosphatidylserine transfer from the endoplasmic reticulum to mitochondria.
1. Traffic - published September 23, 2015
2. Junker M, Rapoport TA
Nucleosome competition reveals processive acetylation by the SAGA HAT module.
1. Proc. Natl. Acad. Sci. U.S.A. - published September 23, 2015
2. Ringel AE, Cieniewicz AM, Taverna SD, Wolberger C
The interplay between the HSV-1 gB cytodomains and the gH cytotail during cell-cell fusion.
1. J. Virol. - published September 23, 2015
2. Rogalin HB, Heldwein EE
Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats.
1. Cell Syst - published September 23, 2015
2. Ori A, Toyama BH, Harris MS, Bock T, Iskar M, Bork P, Ingolia NT, Hetzer MW, Beck M
Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens.
1. Proc. Natl. Acad. Sci. U.S.A. - published September 22, 2015
2. Julien JP, Lee JH, Ozorowski G, Hua Y, Torrents de la Peña A, de Taeye SW, Nieusma T, Cupo A, Yasmeen A, Golabek M, Pugach P, Klasse PJ, Moore JP, Sanders RW, Ward AB, Wilson IA
Structural Features of the αβTCR Mechanotransduction Apparatus That Promote pMHC Discrimination.
1. Front Immunol - published September 22, 2015
2. Brazin KN, Mallis RJ, Das DK, Feng Y, Hwang W, Wang JH, Wagner G, Lang MJ, Reinherz EL
Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS13.
1. J. Thromb. Haemost. - published September 22, 2015
2. Deforche L, Roose E, Vandenbulcke A, Vandeputte N, Feys HB, Springer TA, Mi LZ, Muia J, Sadler JE, Soejima K, Rottensteiner H, Deckmyn H, De Meyer SF, Vanhoorelbeke K
RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications.
1. Crit. Rev. Biochem. Mol. Biol. - published September 22, 2015
2. Xu L, Wang W, Chong J, Shin JH, Xu J, Wang D
Controlled Co-reconstitution of Multiple Membrane Proteins in Lipid Bilayer Nanodiscs Using DNA as a Scaffold.
1. ACS Chem. Biol. - published September 21, 2015
2. Raschle T, Lin C, Jungmann R, Shih WM, Wagner G
How the TRPA1 receptor transmits painful stimuli: Inner workings revealed by electron cryomicroscopy.
1. Bioessays - published September 21, 2015
2. Brewster MS, Gaudet R
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
1. Nat. Med. - published September 21, 2015
2. Mazur PK, Herner A, Mello SS, Wirth M, Hausmann S, Sánchez-Rivera FJ, Lofgren SM, Kuschma T, Hahn SA, Vangala D, Trajkovic-Arsic M, Gupta A, Heid I, Noël PB, Braren R, Erkan M, Kleeff J, Sipos B, Sayles LC, Heikenwalder M, Heßmann E, Ellenrieder V, Esposito I, Jacks T, Bradner JE, Khatri P, Sweet-Cordero EA, Attardi LD, Schmid RM, Schneider G, Sage J, Siveke JT
Structure and multistate function of the transmembrane electron transporter CcdA.
1. Nat. Struct. Mol. Biol. - published September 21, 2015
2. Williamson JA, Cho SH, Ye J, Collet JF, Beckwith JR, Chou JJ
Competition and allostery govern substrate selectivity of cyclooxygenase-2.
1. Proc. Natl. Acad. Sci. U.S.A. - published September 21, 2015
2. Mitchener MM, Hermanson DJ, Shockley EM, Brown HA, Lindsley CW, Reese J, Rouzer CA, Lopez CF, Marnett LJ
The membrane anchor of the transcriptional activator SREBP is characterized by intrinsic conformational flexibility.
1. Proc. Natl. Acad. Sci. U.S.A. - published September 21, 2015
2. Linser R, Salvi N, Briones R, Rovó P, de Groot BL, Wagner G
Thermodynamics of protein destabilization in live cells.
1. Proc. Natl. Acad. Sci. U.S.A. - published September 21, 2015
2. Danielsson J, Mu X, Lang L, Wang H, Binolfi A, Theillet FX, Bekei B, Logan DT, Selenko P, Wennerström H, Oliveberg M
Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts.
1. Behav. Genet. - published September 21, 2015
2. Schwantes-An TH, Zhang J, Chen LS, Hartz SM, Culverhouse RC, Chen X, Coon H, Frank J, Kamens HM, Konte B, Kovanen L, Latvala A, Legrand LN, Maher BS, Melroy WE, Nelson EC, Reid MW, Robinson JD, Shen PH, Yang BZ, Andrews JA, Aveyard P, Beltcheva O, Brown SA, Cannon DS, Cichon S, Corley RP, Dahmen N, Degenhardt L, Foroud T, Gaebel W, Giegling I, Glatt SJ, Grucza RA, Hardin J, Hartmann AM, Heath AC, Herms S, Hodgkinson CA, Hoffmann P, Hops H, Huizinga D, Ising M, Johnson EO, Johnstone E, Kaneva RP, Kendler KS, Kiefer F, Kranzler HR, Krauter KS, Levran O, Lucae S, Lynskey MT, Maier W, Mann K, Martin NG, Mattheisen M, Montgomery GW, Müller-Myhsok B, Murphy MF, Neale MC, Nikolov MA, Nishita D, Nöthen MM, Nurnberger J, Partonen T, Pergadia ML, Reynolds M, Ridinger M, Rose RJ, Rouvinen-Lagerström N, Scherbaum N, Schmäl C, Soyka M, Stallings MC, Steffens M, Treutlein J, Tsuang M, Wall TL, Wodarz N, Yuferov V, Zill P, Bergen AW, Chen J, Cinciripini PM, Edenberg HJ, Ehringer MA, Ferrell RE, Gelernter J, Goldman D, Hewitt JK, Hopfer CJ, Iacono WG, Kaprio J, Kreek MJ, Kremensky IM, Madden PA, McGue M, Munafò MR, Philibert RA, Rietschel M, Roy A, Rujescu D, Saarikoski ST, Swan GE, Todorov AA, Vanyukov MM, Weiss RB, Bierut LJ, Saccone NL
Deletion of Phenylalanine 508 in the First Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator Increases Conformational Exchange and Inhibits Dimerization.
1. J. Biol. Chem. - published September 18, 2015
2. Chong PA, Farber PJ, Vernon RM, Hudson RP, Mittermaier AK, Forman-Kay JD
Influence of Arrestin on the Photodecay of Bovine Rhodopsin.
1. Angew. Chem. Int. Ed. Engl. - published September 18, 2015
2. Chatterjee D, Eckert CE, Slavov C, Saxena K, Fürtig B, Sanders CR, Gurevich VV, Wachtveitl J, Schwalbe H
Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.
1. Mol. Cell - published September 17, 2015
2. Kranzusch PJ, Wilson SC, Lee AS, Berger JM, Doudna JA, Vance RE
Structure of T4moF, the Toluene 4-Monooxygenase Ferredoxin Oxidoreductase.
1. Biochemistry - published September 17, 2015
2. Acheson JF, Moseson H, Fox BG
Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function.
1. Mol. Cell - published September 17, 2015
2. Zeqiraj E, Tian L, Piggott CA, Pillon MC, Duffy NM, Ceccarelli DF, Keszei AF, Lorenzen K, Kurinov I, Orlicky S, Gish GD, Heck AJ, Guarné A, Greenberg RA, Sicheri F
Characterization of Vis Toxin, a Novel ADP-Ribosyltransferase from Vibrio splendidus.
1. Biochemistry - published September 17, 2015
2. Ravulapalli R, Lugo MR, Pfoh R, Visschedyk D, Poole A, Fieldhouse RJ, Pai EF, Merrill AR
An Analysis of MIF Structural Features that Control Functional Activation of CD74.
1. Chem. Biol. - published September 17, 2015
2. Pantouris G, Syed MA, Fan C, Rajasekaran D, Cho TY, Rosenberg EM, Bucala R, Bhandari V, Lolis EJ
Two Essential Light Chains Regulate the MyoA Lever Arm To Promote Toxoplasma Gliding Motility.
1. MBio - published September 17, 2015
2. Williams MJ, Alonso H, Enciso M, Egarter S, Sheiner L, Meissner M, Striepen B, Smith BJ, Tonkin CJ
Contrasting actions of a convulsant barbiturate and its anti-convulsant enantiomer on the α1β3γ2L GABAA receptor account for their in vivo effects.
1. J. Physiol. (Lond.) - published September 17, 2015
2. Desai R, Savechenkov PY, Zolkowska D, Ge RL, Rogawski MA, Bruzik KS, Forman SA, Raines DE, Miller KW
The role of β-arrestin2-dependent signaling in thoracic aortic aneurysm formation in a murine model of Marfan syndrome.
1. Am. J. Physiol. Heart Circ. Physiol. - published September 16, 2015
2. Wisler JW, Harris EM, Raisch M, Mao L, Kim J, Rockman HA, Lefkowitz RJ
The effect of phosphorylation on arrestin-rhodopsin interaction in the squid visual system.
1. J. Neurochem. - published September 16, 2015
2. Robinson KA, Ou WL, Guan X, Sugamori KS, Bandyopadhyay A, Ernst OP, Mitchell J
Requirement of novel amino acid fragments of orphan nuclear receptor TR3/Nur77 for its functions in angiogenesis.
1. Oncotarget - published September 15, 2015
2. Li Y, Bourbon PM, Grant MA, Peng J, Ye T, Zhao D, Zeng H
Resolution of structure of PIP5K1A reveals molecular mechanism for its regulation by dimerization and dishevelled.
1. Nat Commun - published September 15, 2015
2. Hu J, Yuan Q, Kang X, Qin Y, Li L, Ha Y, Wu D
Structure of HCMV glycoprotein B in the postfusion conformation bound to a neutralizing human antibody.
1. Nat Commun - published September 15, 2015
2. Chandramouli S, Ciferri C, Nikitin PA, Caló S, Gerrein R, Balabanis K, Monroe J, Hebner C, Lilja AE, Settembre EC, Carfi A
Establishing the role of ATP for the function of the RIG-I innate immune sensor.
1. Elife - published September 15, 2015
2. Rawling DC, Fitzgerald ME, Pyle AM
Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP.
1. Proc. Natl. Acad. Sci. U.S.A. - published September 15, 2015
2. Vasilyev N, Polonskaia A, Darnell JC, Darnell RB, Patel DJ, Serganov A
The Legionella Anti-autophagy Effector RavZ Targets the Autophagosome via PI3P- and Curvature-Sensing Motifs.
1. Dev. Cell - published September 14, 2015
2. Horenkamp FA, Kauffman KJ, Kohler LJ, Sherwood RK, Krueger KP, Shteyn V, Roy CR, Melia TJ, Reinisch KM
Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family.
1. Nat. Struct. Mol. Biol. - published September 14, 2015
2. Geertsma ER, Chang YN, Shaik FR, Neldner Y, Pardon E, Steyaert J, Dutzler R
Site-selective monitoring of the interaction of the SRA domain of UHRF1 with target DNA sequences labeled by 2-aminopurine.
1. Biochemistry - published September 14, 2015
2. Greiner VJ, Kovalenko L, Humbert N, Richert L, Birck C, Ruff M, Zaporozhets OA, Dhe-Paganon S, Bronner C, Mély Y
Deletion of liaR Reverses Daptomycin Resistance in Enterococcus faecium Independent of the Genetic Background.
1. Antimicrob. Agents Chemother. - published September 14, 2015
2. Panesso D, Reyes J, Gaston EP, Deal M, Londoño A, Nigo M, Munita JM, Miller WR, Shamoo Y, Tran TT, Arias CA
Biochemical methods for studying kinetic regulation of Arf1 activation by Sec7.
1. Methods Cell Biol. - published September 12, 2015
2. Richardson BC, Fromme JC
The inhibitory effects of a RANKL-binding peptide on articular and periarticular bone loss in a murine model of collagen-induced arthritis: a bone histomorphometric study.
1. Arthritis Res. Ther. - published September 12, 2015
2. Kato G, Shimizu Y, Arai Y, Suzuki N, Sugamori Y, Maeda M, Takahashi M, Tamura Y, Wakabayashi N, Murali R, Ono T, Ohya K, Mise-Omata S, Aoki K
Deciphering the Roles of Multicomponent Recognition Signals by the AAA+ Unfoldase ClpX.
1. J. Mol. Biol. - published September 11, 2015
2. Ling L, Montaño SP, Sauer RT, Rice PA, Baker TA
A Structural Snapshot of Type II Pilus Formation in Streptococcus pneumoniae.
1. J. Biol. Chem. - published September 11, 2015
2. Shaik MM, Lombardi C, Maragno Trindade D, Fenel D, Schoehn G, Di Guilmi AM, Dessen A
Management of Choroidal Granulomas Involving the Macula in Corticosteroid-Intolerant Patients.
1. JAMA Ophthalmol - published September 11, 2015
2. Chin EK, Almeida DR, Mahajan VB
Development of electron spin echo envelope modulation spectroscopy to probe the secondary structure of recombinant membrane proteins in a lipid bilayer.
1. Protein Sci. - published September 11, 2015
2. Zhang R, Sahu ID, Gibson KR, Muhammad NB, Bali AP, Comer RG, Liu L, Craig AF, Mccarrick RM, Dabney-Smith C, Sanders CR, Lorigan GA
Structure-Based Design of a Small Molecule CD4-Antagonist with Broad Spectrum Anti-HIV-1 Activity.
1. J. Med. Chem. - published September 10, 2015
2. Curreli F, Kwon YD, Zhang H, Scacalossi D, Belov DS, Tikhonov AA, Andreev IA, Altieri A, Kurkin AV, Kwong PD, Debnath AK
Visualizing virus particle mobility in liquid at the nanoscale.
1. Chem. Commun. (Camb.) - published September 10, 2015
2. Cameron Varano A, Rahimi A, Dukes MJ, Poelzing S, M McDonald S, Kelly DF
Reversible, Specific, Active Aggregates of Endogenous Proteins Assemble upon Heat Stress.
1. Cell - published September 10, 2015
2. Wallace EW, Kear-Scott JL, Pilipenko EV, Schwartz MH, Laskowski PR, Rojek AE, Katanski CD, Riback JA, Dion MF, Franks AM, Airoldi EM, Pan T, Budnik BA, Drummond DA
Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.
1. Cell - published September 10, 2015
2. Scharf L, Wang H, Gao H, Chen S, McDowall AW, Bjorkman PJ
The Touching Tail of a Mechanotransduction Channel.
1. Cell - published September 10, 2015
2. Knecht ZA, Gaudet R, Garrity PA
Using Protein Dimers to Maximize the Protein Hybridization Efficiency with Multisite DNA Origami Scaffolds.
1. PLoS ONE - published September 9, 2015
2. Verma V, Mallik L, Hariadi RF, Sivaramakrishnan S, Skiniotis G, Joglekar AP
Progress toward clonable inorganic nanoparticles.
1. Nanoscale - published September 9, 2015
2. Ni TW, Staicu LC, Nemeth RS, Schwartz CL, Crawford D, Seligman JD, Hunter WJ, Pilon-Smits EA, Ackerson CJ
Structure of the toxic core of α-synuclein from invisible crystals.
1. Nature - published September 9, 2015
2. Rodriguez JA, Ivanova MI, Sawaya MR, Cascio D, Reyes FE, Shi D, Sangwan S, Guenther EL, Johnson LM, Zhang M, Jiang L, Arbing MA, Nannenga BL, Hattne J, Whitelegge J, Brewster AS, Messerschmidt M, Boutet S, Sauter NK, Gonen T, Eisenberg DS
Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses.
1. Cell Host Microbe - published September 9, 2015
2. Moody MA, Gao F, Gurley TC, Amos JD, Kumar A, Hora B, Marshall DJ, Whitesides JF, Xia SM, Parks R, Lloyd KE, Hwang KK, Lu X, Bonsignori M, Finzi A, Vandergrift NA, Alam SM, Ferrari G, Shen X, Tomaras GD, Kamanga G, Cohen MS, Sam NE, Kapiga S, Gray ES, Tumba NL, Morris L, Zolla-Pazner S, Gorny MK, Mascola JR, Hahn BH, Shaw GM, Sodroski JG, Liao HX, Montefiori DC, Hraber PT, Korber BT, Haynes BF
Structural basis underlying CAC RNA recognition by the RRM domain of dimeric RNA-binding protein RBPMS.
1. Q. Rev. Biophys. - published September 8, 2015
2. Teplova M, Farazi TA, Tuschl T, Patel DJ
Structure of a bacterial RNA polymerase holoenzyme open promoter complex.
1. Elife - published September 8, 2015
2. Bae B, Feklistov A, Lass-Napiorkowska A, Landick R, Darst SA
Structural determinants of nuclear export signal orientation in binding CRM1.
1. Elife - published September 8, 2015
2. Fung HY, Fu SC, Brautigam CA, Chook YM
CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex.
1. Elife - published September 8, 2015
2. Bae B, Chen J, Davis E, Leon K, Darst SA, Campbell EA
In the Right Place at the Right Time: Is TMC1/2 the Transduction Channel for Hearing?
1. Cell Rep - published September 8, 2015
2. Indzhykulian AA, Corey DP
Peptide dimer structure in an Aβ(1-42) fibril visualized with cryo-EM.
1. Proc. Natl. Acad. Sci. U.S.A. - published September 8, 2015
2. Schmidt M, Rohou A, Lasker K, Yadav JK, Schiene-Fischer C, Fändrich M, Grigorieff N
Human HLTF mediates postreplication repair by its HIRAN domain-dependent replication fork remodelling.
1. Nucleic Acids Res. - published September 8, 2015
2. Achar YJ, Balogh D, Neculai D, Juhasz S, Morocz M, Gali H, Dhe-Paganon S, Venclovas Č, Haracska L
Structure of a CGI-58 Motif Provides the Molecular Basis of Lipid Droplet Anchoring.
1. J. Biol. Chem. - published September 8, 2015
2. Boeszoermenyi A, Nagy HM, Arthanari H, Pillip CJ, Lindermuth H, Luna RE, Wagner G, Zechner R, Zangger K, Oberer M
Biomolecular DNP-Supported NMR Spectroscopy using Site-Directed Spin Labeling.
1. Chemistry - published September 7, 2015
2. van der Cruijsen EA, Koers EJ, Sauvée C, Hulse RE, Weingarth M, Ouari O, Perozo E, Tordo P, Baldus M
An interconnected hierarchical model of cell death regulation by the BCL-2 family.
1. Nat. Cell Biol. - published September 7, 2015
2. Chen HC, Kanai M, Inoue-Yamauchi A, Tu HC, Huang Y, Ren D, Kim H, Takeda S, Reyna DE, Chan PM, Ganesan YT, Liao CP, Gavathiotis E, Hsieh JJ, Cheng EH
Structure of mammalian eIF3 in the context of the 43S preinitiation complex.
1. Nature - published September 7, 2015
2. des Georges A, Dhote V, Kuhn L, Hellen CU, Pestova TV, Frank J, Hashem Y
Crystal structures of a double-barrelled fluoride ion channel.
1. Nature - published September 7, 2015
2. Stockbridge RB, Kolmakova-Partensky L, Shane T, Koide A, Koide S, Miller C, Newstead S
A Crystallin Fold in the Interleukin-4-inducing Principle of Schistosoma mansoni Eggs (IPSE/α-1) Mediates IgE Binding for Antigen-independent Basophil Activation.
1. J. Biol. Chem. - published September 4, 2015
2. Meyer NH, Mayerhofer H, Tripsianes K, Blindow S, Barths D, Mewes A, Weimar T, Köhli T, Bade S, Madl T, Frey A, Haas H, Mueller-Dieckmann J, Sattler M, Schramm G
Generation of Multiple Reporter Ions from a Single Isobaric Reagent Increases Multiplexing Capacity for Quantitative Proteomics.
1. Anal. Chem. - published September 4, 2015
2. Braun CR, Bird GH, Wühr M, Erickson BK, Rad R, Walensky LD, Gygi SP, Haas W
A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism.
1. Nat Commun - published September 4, 2015
2. Krarup A, Truan D, Furmanova-Hollenstein P, Bogaert L, Bouchier P, Bisschop IJ, Widjojoatmodjo MN, Zahn R, Schuitemaker H, McLellan JS, Langedijk JP
Novel mutations in PIEZO1 cause an autosomal recessive generalized lymphatic dysplasia with non-immune hydrops fetalis.
1. Nat Commun - published September 4, 2015
2. Fotiou E, Martin-Almedina S, Simpson MA, Lin S, Gordon K, Brice G, Atton G, Jeffery I, Rees DC, Mignot C, Vogt J, Homfray T, Snyder MP, Rockson SG, Jeffery S, Mortimer PS, Mansour S, Ostergaard P
Sph3 is a glycoside hydrolase required for the biosynthesis of galactosaminogalactan in Aspergillus fumigates.
1. J. Biol. Chem. - published September 4, 2015
2. Bamford NC, Snarr BD, Gravelat FN, Little DJ, Lee MJ, Zacharias CA, Chabot JC, Geller AM, Baptista SD, Baker P, Robinson H, Howell PL, Sheppard DC
A network of SMG-8, SMG-9 and SMG-1 C-terminal insertion domain regulates UPF1 substrate recruitment and phosphorylation.
1. Nucleic Acids Res. - published September 3, 2015
2. Deniaud A, Karuppasamy M, Bock T, Masiulis S, Huard K, Garzoni F, Kerschgens K, Hentze MW, Kulozik AE, Beck M, Neu-Yilik G, Schaffitzel C
Nucleic acid-binding specificity of human FUS protein.
1. Nucleic Acids Res - published September 3, 2015
2. Wang X, Schwartz JC, Cech TR
TAF11 Assembles the RISC Loading Complex to Enhance RNAi Efficiency.
1. Mol. Cell - published September 3, 2015
2. Liang C, Wang Y, Murota Y, Liu X, Smith D, Siomi MC, Liu Q
Manipulation of the host protein acetylation network by human immunodeficiency virus type 1.
1. Crit Rev Biochem Mol Biol - published September 3, 2015
2. Jeng MY, Ali I, Ott M
Blue Electrogenerated Chemiluminescence from Water-Soluble Iridium Complexes Containing Sulfonated Phenylpyridine or Tetraethylene Glycol Derivatized Triazolylpyridine Ligands.
1. Chemistry - published September 3, 2015
2. Kerr E, Doeven EH, Barbante GJ, Connell TU, Donnelly PS, Wilson DJ, Ashton TD, Pfeffer FM, Francis PS
The Crystal Structure of Pneumolysin at 2.0 Å Resolution Reveals the Molecular Packing of the Pre-pore Complex.
1. Sci Rep - published September 3, 2015
2. Marshall JE, Faraj BH, Gingras AR, Lonnen R, Sheikh MA, El-Mezgueldi M, Moody PC, Andrew PW, Wallis R
Does the Transcription Factor NemR Use a Regulatory Sulfenamide Bond to Sense Bleach?
1. Antioxid Redox Signal - published September 2, 2015
2. Gray MJ, Li Y, Leichert LI, Xu Z, Jakob U
The Signature of the Five-Stranded vRRM Fold Defined by Functional, Structural and Computational Analysis of the hnRNP L Protein.
1. J Mol Biol - published September 2, 2015
2. Blatter M, Dunin-Horkawicz S, Grishina I, Maris C, Thore S, Maier T, Bindereif A, Bujnicki JM, Allain FH
Structure and Function of Cu(I)- and Zn(II)-ATPases.
1. Biochemistry - published September 2, 2015
2. Sitsel O, Grønberg C, Autzen HE, Wang K, Meloni G, Nissen P, Gourdon P
Chorismatase Mechanisms Reveal Fundamentally Different Types of Reaction in a Single Conserved Protein Fold.
1. J Am Chem Soc - published September 2, 2015
2. Hubrich F, Juneja P, Müller M, Diederichs K, Welte W, Andexer JN
Extended O-GlcNAc on HLA Class-I-Bound Peptides.
1. J Am Chem Soc - published September 2, 2015
2. Marino F, Bern M, Mommen GPM, Leney AC, van Gaans-van den Brink JAM, Bonvin AMJJ, Becker C, van Els CACM, Heck AJR
Multimodal Chemosensory Circuits Controlling Male Courtship in Drosophila.
1. Neuron - published September 2, 2015
2. Clowney EJ, Iguchi S, Bussell JJ, Scheer E, Ruta V
Activation of Hsp90 Enzymatic Activity and Conformational Dynamics through Rationally Designed Allosteric Ligands.
1. Chemistry - published September 2, 2015
2. Sattin S, Tao J, Vettoretti G, Moroni E, Pennati M, Lopergolo A, Morelli L, Bugatti A, Zuehlke A, Moses M, Prince T, Kijima T, Beebe K, Rusnati M, Neckers L, Zaffaroni N, Agard DA, Bernardi A, Colombo G
Truncated forms of the prion protein PrP demonstrate the need for complexity in prion structure.
1. Prion - published September 2, 2015
2. Wan W, Stöhr J, Kendall A, Stubbs G
Sphingomyelin, ORAI1 channels, and cellular Ca2+ signaling.
1. J. Gen. Physiol. - published September 2, 2015
2. Hogan PG
Parkinson's disease: Crystals of a toxic core.
1. Nature - published September 2, 2015
2. Goedert M, Cheng Y
Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif.
1. J Am Chem Soc - published September 2, 2015
2. Hayouka Z, Thomas NC, Mortenson DE, Satyshur KA, Weisblum B, Forest KT, Gellman SH
Rac1 plays an essential role in axon growth and guidance and in neuronal survival in the central and peripheral nervous systems.
1. Neural Dev - published September 2, 2015
2. Hua ZL, Emiliani FE, Nathans J
Structural insights into endoplasmic reticulum stored calcium regulation by inositol 1,4,5-trisphosphate and ryanodine receptors.
1. Biochim Biophys Acta - published September 1, 2015
2. Seo MD, Enomoto M, Ishiyama N, Stathopulos PB, Ikura M
What a difference a cluster makes: The multifaceted roles of IscR in gene regulation and DNA recognition.
1. Biochim Biophys Acta - published September 1, 2015
2. Santos JA, Pereira PJ, Macedo-Ribeiro S
Direct visualization of vaults within intact cells by electron cryo-tomography.
1. Cell Mol Life Sci - published September 1, 2015
2. Woodward CL, Mendonça LM, Jensen GJ
Developments in cryo-electron tomography for in situ structural analysis.
1. Arch. Biochem. Biophys. - published September 1, 2015
2. Dubrovsky A, Sorrentino S, Harapin J, Sapra KT, Medalia O
Nickel-responsive transcriptional regulators.
1. Metallomics - published September 1, 2015
2. Musiani F, Zambelli B, Bazzani M, Mazzei L, Ciurli S
Validation methods for low-resolution fitting of atomic structures to electron microscopy data.
1. Arch. Biochem. Biophys. - published September 1, 2015
2. Xu XP, Volkmann N
Oncogenic mutations weaken the interactions that stabilize the p110α-p85α heterodimer in phosphatidylinositol 3-kinase α.
1. FEBS J - published September 1, 2015
2. Echeverria I, Liu Y, Gabelli SB, Amzel LM
Electron self-exchange in hemoglobins revealed by deutero-hemin substitution.
1. J Inorg Biochem - published September 1, 2015
2. Athwal NS, Alagurajan J, Sturms R, Fulton DB, Andreotti AH, Hargrove MS
Inferring transient particle transport dynamics in live cells.
1. Nat Methods - published September 1, 2015
2. Monnier N, Barry Z, Park HY, Su KC, Katz Z, English BP, Dey A, Pan K, Cheeseman IM, Singer RH, Bathe M
On the interaction of Helicobacter pylori NikR, a Ni(II)-responsive transcription factor, with the urease operator: in solution and in silico studies.
1. J Biol Inorg Chem - published September 1, 2015
2. Mazzei L, Dobrovolska O, Musiani F, Zambelli B, Ciurli S
The Closing Mechanism of DNA Polymerase I at Atomic Resolution.
1. Structure - published September 1, 2015
2. Miller BR, Beese LS, Parish CA, Wu EY
ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space.
1. Nat Methods - published September 1, 2015
2. Chari A, Haselbach D, Kirves JM, Ohmer J, Paknia E, Fischer N, Ganichkin O, Möller V, Frye JJ, Petzold G, Jarvis M, Tietzel M, Grimm C, Peters JM, Schulman BA, Tittmann K, Markl J, Fischer U, Stark H
Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion.
1. Structure - published September 1, 2015
2. Lu YC, Nazarko OV, Sando R, Salzman GS, Südhof TC, Araç D
A YidC-like Protein in the Archaeal Plasma Membrane.
1. Structure - published September 1, 2015
2. Borowska MT, Dominik PK, Anghel SA, Kossiakoff AA, Keenan RJ
Precision Hypofractionated Radiation Therapy in Poor Performing Patients With Non-Small Cell Lung Cancer: Phase 1 Dose Escalation Trial.
1. Int. J. Radiat. Oncol. Biol. Phys. - published September 1, 2015
2. Westover KD, Loo BW, Gerber DE, Iyengar P, Choy H, Diehn M, Hughes R, Schiller J, Dowell J, Wardak Z, Sher D, Christie A, Xie XJ, Corona I, Sharma A, Wadsworth ME, Timmerman R
Structural implications of weak Ca2+ block in Drosophila cyclic nucleotide-gated channels.
1. J Gen Physiol - published September 1, 2015
2. Lam YL, Zeng W, Derebe MG, Jiang Y
Response from Tanley et al. to Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin.
1. Acta Crystallogr D Biol Crystallogr - published September 1, 2015
2. Tanley SW, Diederichs K, Kroon-Batenburg LM, Levy C, Schreurs AM, Helliwell JR
Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits.
1. Elife - published September 1, 2015
2. Acosta-Alvear D, Cho MY, Wild T, Buchholz TJ, Lerner AG, Simakova O, Hahn J, Korde N, Landgren O, Maric I, Choudhary C, Walter P, Weissman JS, Kampmann M
Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1.
1. Acta Crystallogr. D Biol. Crystallogr. - published September 1, 2015
2. Park J, Guggisberg AM, Odom AR, Tolia NH
The Complex Energy Landscape of the Protein IscU.
1. Biophys. J. - published September 1, 2015
2. Bothe JR, Tonelli M, Ali IK, Dai Z, Frederick RO, Westler WM, Markley JL
Cryo-EM: Spinning the Micelles Away.
1. Structure - published September 1, 2015
2. Singh SK, Sigworth FJ
Neisseria meningitidis Type IV Pili Composed of Sequence Invariable Pilins Are Masked by Multisite Glycosylation.
1. PLoS Pathog - published September 1, 2015
2. Gault J, Ferber M, Machata S, Imhaus AF, Malosse C, Charles-Orszag A, Millien C, Bouvier G, Bardiaux B, Péhau-Arnaudet G, Klinge K, Podglajen I, Ploy MC, Seifert HS, Nilges M, Chamot-Rooke J, Duménil G
The molecular mechanism of nuclear transport revealed by atomic-scale measurements.
1. Elife - published September 1, 2015
2. Hough LE, Dutta K, Sparks S, Temel DB, Kamal A, Tetenbaum-Novatt J, Rout MP, Cowburn D
ER-mitochondrial junctions can be bypassed by dominant mutations in the endosomal protein Vps13.
1. J Cell Biol - published September 1, 2015
2. Lang AB, John Peter AT, Walter P, Kornmann B
High-level production of membrane proteins in E. coli BL21(DE3) by omitting the inducer IPTG.
1. Microb Cell Fact - published September 1, 2015
2. Zhang Z, Kuipers G, Niemiec Ł, Baumgarten T, Slotboom DJ, de Gier JW, Hjelm A
Modulation of the Host Lipid Landscape to Promote RNA Virus Replication: The Picornavirus Encephalomyocarditis Virus Converges on the Pathway Used by Hepatitis C Virus.
1. PLoS Pathog - published September 1, 2015
2. Dorobantu CM, Albulescu L, Harak C, Feng Q, van Kampen M, Strating JR, Gorbalenya AE, Lohmann V, van der Schaar HM, van Kuppeveld FJ