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129 Member Publications for May 2015

Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site.
1. PLoS Pathog. - published May 30, 2015
2. Crooks ET, Tong T, Chakrabarti B, Narayan K, Georgiev IS, Menis S, Huang X, Kulp D, Osawa K, Muranaka J, Stewart-Jones G, Destefano J, O'Dell S, LaBranche C, Robinson JE, Montefiori DC, McKee K, Du SX, Doria-Rose N, Kwong PD, Mascola JR, Zhu P, Schief WR, Wyatt RT, Whalen RG, Binley JM
The EBNA-2 N-Terminal Transactivation Domain Folds into a Dimeric Structure Required for Target Gene Activation.
1. PLoS Pathog. - published May 30, 2015
2. Friberg A, Thumann S, Hennig J, Zou P, Nössner E, Ling PD, Sattler M, Kempkes B
Effect of internal limiting membrane abrasion on retinal tissues in macular holes.
1. Invest. Ophthalmol. Vis. Sci. - published May 30, 2015
2. Almeida DR, Chin EK, Tarantola RM, Folk JC, Boldt HC, Skeie JM, Mullins RF, Russell SR, Mahajan VB
Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris.
1. J. Biomol. NMR - published May 30, 2015
2. Clark L, Zahm JA, Ali R, Kukula M, Bian L, Patrie SM, Gardner KH, Rosen MK, Rosenbaum DM
eIF1A augments Ago2-mediated Dicer-independent miRNA biogenesis and RNA interference.
1. Nat Commun - published May 29, 2015
2. Yi T, Arthanari H, Akabayov B, Song H, Papadopoulos E, Qi HH, Jedrychowski M, Güttler T, Guo C, Luna RE, Gygi SP, Huang SA, Wagner G
Proteomic insight into the molecular function of the vitreous.
1. PLoS ONE - published May 29, 2015
2. Skeie JM, Roybal CN, Mahajan VB
Tag and Capture Flow Hydrogen Exchange Mass Spectrometry with a Fluorous-Immobilized Probe.
1. Anal. Chem. - published May 29, 2015
2. Marcsisin SR, Liptak C, Marineau J, Bradner JE, Engen JR
Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6.
1. Elife - published May 29, 2015
2. Grant T, Grigorieff N
ADAPT-NMR 3.0: utilization of BEST-type triple-resonance NMR experiments to accelerate the process of data collection and assignment.
1. J. Biomol. NMR - published May 29, 2015
2. Dashti H, Tonelli M, Markley JL
Candida albicans kinesin Kar3 depends on a Cik1-like regulatory partner protein for its roles in mating, cell morphogenesis and bipolar spindle formation.
1. Eukaryotic Cell - published May 29, 2015
2. Frazer C, Joshi M, Delorme C, Davis D, Bennett RJ, Allingham JS
DisVis: Quantifying and visualizing accessible interaction space of distance-restrained biomolecular complexes.
1. Bioinformatics - published May 29, 2015
2. van Zundert GC, Bonvin AM
Ordered Regions of Channel Nucleoporins Nup62, Nup54 and Nup58 Form Dynamic Complexes in Solution.
1. J. Biol. Chem. - published May 29, 2015
2. Sharma A, Solmaz SR, Blobel G, Melčák I
Preformed Soluble Chemoreceptor Trimers That Mimic Cellular Assembly States and Activate CheA Autophosphorylation.
1. Biochemistry - published May 28, 2015
2. Greenswag AR, Li X, Borbat PP, Samanta D, Watts KJ, Freed JH, Crane BR
Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase η and Sulfolobus solfataricus P2 Polymerase IV.
1. J. Am. Chem. Soc. - published May 27, 2015
2. Patra A, Banerjee S, Johnson Salyard TL, Malik CK, Christov PP, Rizzo CJ, Stone MP, Egli M
Biochemical and Proteomic Analysis of Ubiquitination of Hsc70 and Hsp70 by the E3 Ligase CHIP.
1. PLoS ONE - published May 27, 2015
2. Soss SE, Rose KL, Hill S, Jouan S, Chazin WJ
BCL::SAXS: GPU accelerated debye method for computation of small angle X Ray scattering profiles.
1. Proteins - published May 27, 2015
2. Putnam DK, Weiner BE, Woetzel N, Lowe EW, Meiler J
Comparative Analysis of the Glycosylation Profiles of Membrane-anchored HIV-1 Envelope Glycoprotein Trimers and Soluble gp140.
1. J. Virol. - published May 27, 2015
2. Go EP, Herschhorn A, Gu C, Castillo-Menendez L, Zhang S, Mao Y, Chen H, Ding H, Wakefield JK, Hua D, Liao HX, Kappes JC, Sodroski J, Desaire H
Nature's Enzymes Tricked with Xenobiotic Oxidants.
1. ACS Cent Sci - published May 27, 2015
2. Yudin AK
Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity.
1. Cell Rep - published May 26, 2015
2. Kane JR, Stanley DJ, Hultquist JF, Johnson JR, Mietrach N, Binning JM, Jónsson SR, Barelier S, Newton BW, Johnson TL, Franks-Skiba KE, Li M, Brown WL, Gunnarsson HI, Adalbjornsdóttir A, Fraser JS, Harris RS, Andrésdóttir V, Gross JD, Krogan NJ
ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins.
1. Elife - published May 26, 2015
2. Caballe A, Wenzel DM, Agromayor M, Alam SL, Skalicky JJ, Kloc M, Carlton JG, Labrador L, Sundquist WI, Martin-Serrano J
BCL-2 family member BOK promotes apoptosis in response to endoplasmic reticulum stress.
1. Proc. Natl. Acad. Sci. U.S.A. - published May 26, 2015
2. Carpio MA, Michaud M, Zhou W, Fisher JK, Walensky LD, Katz SG
Solid-Phase Parallel Synthesis of Functionalised Medium-to-Large Cyclic Peptidomimetics through Three-Component Coupling Driven by Aziridine Aldehyde Dimers.
1. Chemistry - published May 26, 2015
2. Treder AP, Hickey JL, Tremblay MC, Zaretsky S, Scully CC, Mancuso J, Doucet A, Yudin AK, Marsault E
Characterization of poliovirus neutralization escape mutants of single-domain antibody fragments (VHHs).
1. Antimicrob. Agents Chemother. - published May 26, 2015
2. Schotte L, Thys B, Strauss M, Filman DJ, Rombaut B, Hogle JM
Structural and functional studies of membrane remodeling machines.
1. Methods Cell Biol - published May 23, 2015
2. Kalia R, Talledge N, Frost A
A combined NMR and computational approach to investigate Peptide binding to a designed armadillo repeat protein.
1. J. Mol. Biol. - published May 22, 2015
2. Ewald C, Christen MT, Watson RP, Mihajlovic M, Zhou T, Honegger A, Plückthun A, Caflisch A, Zerbe O
Simultaneously Targeting the NS3 Protease and Helicase Activities for More Effective Hepatitis C Virus Therapy.
1. ACS Chem. Biol. - published May 22, 2015
2. Ndjomou J, Corby MJ, Sweeney NL, Hanson AM, Aydin C, Ali A, Schiffer CA, Li K, Frankowski KJ, Schoenen FJ, Frick DN
The Expression of Functional Vpx during Pathogenic SIVmac Infections of Rhesus Macaques Suppresses SAMHD1 in CD4+ Memory T Cells.
1. PLoS Pathog. - published May 22, 2015
2. Shingai M, Welbourn S, Brenchley JM, Acharya P, Miyagi E, Plishka RJ, Buckler-White A, Kwong PD, Nishimura Y, Strebel K, Martin MA
The metabolic syndrome and severity of diabetic retinopathy.
1. Clin Ophthalmol - published May 22, 2015
2. Chen JJ, Wendel LJ, Birkholz ES, Vallone JG, Coleman AL, Yu F, Mahajan VB
Molecular interactions of the Saccharomyces cerevisiae Atg1 complex provide insights into assembly and regulatory mechanisms.
1. Autophagy - published May 22, 2015
2. Chew LH, Lu S, Liu X, Li FK, Yu AY, Klionsky DJ, Dong MQ, Yip CK
Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases.
1. Cell - published May 21, 2015
2. Garnham CP, Vemu A, Wilson-Kubalek EM, Yu I, Szyk A, Lander GC, Milligan RA, Roll-Mecak A
Viral Receptor-Binding Site Antibodies with Diverse Germline Origins.
1. Cell - published May 21, 2015
2. Schmidt AG, Therkelsen MD, Stewart S, Kepler TB, Liao HX, Moody MA, Haynes BF, Harrison SC
Biochemical, Kinetic, and Spectroscopic Characterization of Ruegeria pomeroyi DddW-A Mononuclear Iron-Dependent DMSP Lyase.
1. PLoS ONE - published May 21, 2015
2. Brummett AE, Schnicker NJ, Crider A, Todd JD, Dey M
Human gamma delta T cells: Evolution and ligand recognition.
1. Cell. Immunol. - published May 21, 2015
2. Adams EJ, Gu S, Luoma AM
Different polyamine pathways from bacteria have replaced eukaryotic spermidine biosynthesis in ciliates Tetrahymena thermophila and Paramecium tetaurelia.
1. Mol. Microbiol. - published May 21, 2015
2. Li B, Kim SH, Zhang Y, Hanfrey CC, Elliott KA, Ealick SE, Michael AJ
Phthalimide conjugation as a strategy for in vivo target protein degradation.
1. Science - published May 21, 2015
2. Winter GE, Buckley DL, Paulk J, Roberts JM, Souza A, Dhe-Paganon S, Bradner JE
Expanding the Biologist's Toolkit with CRISPR-Cas9.
1. Mol. Cell - published May 21, 2015
2. Sternberg SH, Doudna JA
Evolutionary Dynamics of the Cellulose Synthase Gene Superfamily in Grasses.
1. Plant Physiol. - published May 21, 2015
2. Schwerdt JG, MacKenzie K, Wright F, Oehme D, Wagner JM, Harvey AJ, Shirley NJ, Burton RA, Schreiber M, Halpin C, Zimmer J, Marshall DF, Waugh R, Fincher GB
The Effect of Detergent, Temperature, and Lipid on the Oligomeric State of MscL Constructs: Insights from Mass Spectrometry.
1. Chem. Biol. - published May 21, 2015
2. Reading E, Walton TA, Liko I, Marty MT, Laganowsky A, Rees DC, Robinson CV
Structures to complement the archaeo-eukaryotic primases catalytic cycle description: What's next?
1. Comput Struct Biotechnol J - published May 20, 2015
2. Boudet J, Devillier JC, Allain FH, Lipps G
Ser or Leu: structural snapshots of mistranslation in Candida albicans.
1. Front Mol Biosci - published May 20, 2015
2. Sárkány Z, Silva A, Pereira PJ, Macedo-Ribeiro S
Advanced glycation end products facilitate bacterial adherence in urinary tract infection in diabetic mice.
1. Pathog Dis - published May 20, 2015
2. Ozer A, Altuntas CZ, Izgi K, Bicer F, Hultgren SJ, Liu G, Daneshgari F
Assessing hepatic fibrosis: comparing the intravoxel incoherent motion in MRI with acoustic radiation force impulse imaging in US.
1. Eur Radiol - published May 20, 2015
2. Wu CH, Ho MC, Jeng YM, Liang PC, Hu RH, Lai HS, Shih TT
Orotidine Monophosphate Decarboxylase--A Fascinating Workhorse Enzyme with Therapeutic Potential.
1. J Genet Genomics - published May 20, 2015
2. Fujihashi M, Mnpotra JS, Mishra RK, Pai EF, Kotra LP
The Transcription Factor CarH Safeguards Use of Adenosylcobalamin as a Light Sensor by Altering the Photolysis Products.
1. Biochemistry - published May 19, 2015
2. Jost M, Simpson JH, Drennan CL
Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis.
1. Nat Commun - published May 19, 2015
2. Xue J, Sharma V, Hsieh MH, Chawla A, Murali R, Pandol SJ, Habtezion A
Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.
1. Immunity - published May 19, 2015
2. Spangler JB, Tomala J, Luca VC, Jude KM, Dong S, Ring AM, Votavova P, Pepper M, Kovar M, Garcia KC
Interleukin-2 Activity Can Be Fine Tuned with Engineered Receptor Signaling Clamps.
1. Immunity - published May 19, 2015
2. Mitra S, Ring AM, Amarnath S, Spangler JB, Li P, Ju W, Fischer S, Oh J, Spolski R, Weiskopf K, Kohrt H, Foley JE, Rajagopalan S, Long EO, Fowler DH, Waldmann TA, Garcia KC, Leonard WJ
Modeling macromolecular motions by x-ray-scattering-constrained molecular dynamics.
1. Biophys. J. - published May 19, 2015
2. Rambo RP, Tainer JA
When Are Antifreeze Proteins in Solution Essential for Ice Growth Inhibition?
1. Langmuir - published May 18, 2015
2. Drori R, Davies PL, Braslavsky I
Structure of the Vif-binding domain of the antiviral enzyme APOBEC3G.
1. Nat. Struct. Mol. Biol. - published May 18, 2015
2. Kouno T, Luengas EM, Shigematsu M, Shandilya SM, Zhang J, Chen L, Hara M, Schiffer CA, Harris RS, Matsuo H
Probing a cell-embedded megadalton protein complex by DNP-supported solid-state NMR.
1. Nat. Methods - published May 18, 2015
2. Kaplan M, Cukkemane A, van Zundert GC, Narasimhan S, Daniëls M, Mance D, Waksman G, Bonvin AM, Fronzes R, Folkers GE, Baldus M
Performance of the WeNMR CS-Rosetta3 web server in CASD-NMR.
1. J. Biomol. NMR - published May 17, 2015
2. van der Schot G, Bonvin AM
A New Family of HEAT-Like Repeat Proteins Lacking a Critical Substrate Recognition Motif Present in Related DNA Glycosylases.
1. PLoS ONE - published May 16, 2015
2. Mullins EA, Shi R, Kotsch LA, Eichman BF
Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALL.
1. Clin. Cancer Res. - published May 15, 2015
2. Stubbs MC, Kim W, Bariteau M, Davis T, Vempati S, Minehart J, Witkin M, Qi J, Krivtsov AV, Bradner JE, Kung AL, Armstrong SA
Structural basis of substrate specificity and regiochemistry in the MycF/TylF family of sugar O-methyltransferases.
1. ACS Chem. Biol. - published May 15, 2015
2. Bernard SM, Akey DL, Tripathi A, Park SR, Konwerski JR, Anzai Y, Li S, Kato F, Sherman DH, Smith JL
Dimeric c-di-GMP Is Required for Post-translational Regulation of Alginate Production in Pseudomonas aeruginosa.
1. J. Biol. Chem. - published May 15, 2015
2. Whitney JC, Whitfield GB, Marmont LS, Yip P, Neculai AM, Lobsanov YD, Robinson H, Ohman DE, Howell PL
A nanotherapy strategy significantly enhances anticryptosporidial activity of an inhibitor of bifunctional thymidylate synthase-dihydrofolate reductase from Cryptosporidium.
1. Bioorg. Med. Chem. Lett. - published May 15, 2015
2. Mukerjee A, Iyidogan P, Castellanos-Gonzalez A, Cisneros JA, Czyzyk D, Ranjan AP, Jorgensen WL, White AC, Vishwanatha JK, Anderson KS
Copper Binding to the N-Terminally Acetylated, Naturally Occurring Form of Alpha-Synuclein Induces Local Helical Folding.
1. J. Am. Chem. Soc. - published May 15, 2015
2. Miotto MC, Valiente-Gabioud AA, Rossetti G, Zweckstetter M, Carloni P, Selenko P, Griesinger C, Binolfi A, Fernández CO
A Multiplexed NMR-Reporter Approach to Measure Cellular Kinase and Phosphatase Activities in Real-Time.
1. J. Am. Chem. Soc. - published May 15, 2015
2. Thongwichian R, Kosten J, Benary U, Rose HM, Stuiver M, Theillet FX, Dose A, Koch B, Yokoyama H, Schwarzer D, Wolf J, Selenko P
TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms.
1. EMBO J. - published May 15, 2015
2. Kim B, Ha M, Loeff L, Chang H, Simanshu DK, Li S, Fareh M, Patel DJ, Joo C, Kim VN
Cryo-Electron Microscopy and the Amazing Race to Atomic Resolution.
1. Biochemistry - published May 14, 2015
2. Binshtein E, Ohi MD
Post-crystallization Improvement of RNA Crystal Diffraction Quality.
1. Methods Mol Biol - published May 14, 2015
2. Zhang J, Ferré-D'Amaré AR
Bio301: A Web-Based EST Annotation Pipeline That Facilitates Functional Comparison Studies.
1. ISRN Bioinform - published May 14, 2015
2. Chen YC, Chen YC, Lin WD, Hsiao CD, Chiu HW, Ho JM
Structural analyses of the chromatin remodelling enzymes INO80-C and SWR-C.
1. Nat Commun - published May 13, 2015
2. Watanabe S, Tan D, Lakshminarasimhan M, Washburn MP, Erica Hong EJ, Walz T, Peterson CL
Pseudomonas moraviensis subsp. stanleyae, a bacterial endophyte of hyperaccumulator Stanleya pinnata, is capable of efficient selenite reduction to elemental selenium under aerobic conditions.
1. J. Appl. Microbiol. - published May 13, 2015
2. Staicu LC, Ackerson CJ, Cornelis P, Ye L, Berendsen RL, Hunter WJ, Noblitt SD, Henry CS, Cappa JJ, Montenieri RL, Wong AO, Musilova L, Sura-de Jong M, van Hullebusch ED, Lens PN, Reynolds RJ, Pilon-Smits EA
A novel sound-blocking structure based on the muffler principle for rib-sparing transcostal high-intensity focused ultrasound treatment.
1. Int J Hyperthermia - published May 13, 2015
2. Chao YT, Hsu CJ, Yu YL, Yen JY, Ho MC, Chen YY, Chang HC, Lian FL
Biochemical and Structural Analysis of an Eis Family Aminoglycoside Acetyltransferase from Bacillus anthracis.
1. Biochemistry - published May 12, 2015
2. Green KD, Biswas T, Chang C, Wu R, Chen W, Janes BK, Chalupska D, Gornicki P, Hanna PC, Tsodikov OV, Joachimiak A, Garneau-Tsodikova S
Structure and mechanism of the T-box riboswitches.
1. Wiley Interdiscip Rev RNA - published May 12, 2015
2. Zhang J, Ferré-D'Amaré AR
Structural analysis of multicellular organisms with cryo-electron tomography.
1. Nat. Methods - published May 11, 2015
2. Harapin J, Börmel M, Sapra KT, Brunner D, Kaech A, Medalia O
A conserved histidine modulates HSPB5 structure to trigger chaperone activity in response to stress-related acidosis.
1. Elife - published May 11, 2015
2. Rajagopal P, Tse E, Borst AJ, Delbecq SP, Shi L, Southworth DR, Klevit RE
SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition.
1. Cancer Cell - published May 11, 2015
2. Kim E, Ilagan JO, Liang Y, Daubner GM, Lee SC, Ramakrishnan A, Li Y, Chung YR, Micol JB, Murphy ME, Cho H, Kim MK, Zebari AS, Aumann S, Park CY, Buonamici S, Smith PG, Deeg HJ, Lobry C, Aifantis I, Modis Y, Allain FH, Halene S, Bradley RK, Abdel-Wahab O
Bhlhe40 represses PGC-1α activity on metabolic gene promoters in myogenic cells.
1. Mol. Cell. Biol. - published May 11, 2015
2. Chung SY, Kao CH, Villarroya F, Chang HY, Chang HC, Hsiao SP, Liou GG, Chen SL
The human antimicrobial protein calgranulin C (S100A12) participates in control of Helicobacter pylori growth and regulation of virulence.
1. Infect. Immun. - published May 11, 2015
2. Haley KP, Delgado AG, Piazuelo MB, Mortensen BL, Correa P, Damo SM, Chazin WJ, Skaar EP, Gaddy JA
Increased resolution of aromatic cross peaks using alternate (13)C labeling and TROSY.
1. J. Biomol. NMR - published May 10, 2015
2. Milbradt AG, Arthanari H, Takeuchi K, Boeszoermenyi A, Hagn F, Wagner G
Accounting for Experimental Noise Reveals That mRNA Levels, Amplified by Post-Transcriptional Processes, Largely Determine Steady-State Protein Levels in Yeast.
1. PLoS Genet. - published May 8, 2015
2. Csárdi G, Franks A, Choi DS, Airoldi EM, Drummond DA
Biophysical Approaches to the Study of LeuT, a Prokaryotic Homolog of Neurotransmitter Sodium Symporters.
1. Meth. Enzymol. - published May 8, 2015
2. Singh SK, Pal A
Low cost, high performance processing of single particle cryo-electron microscopy data in the cloud.
1. Elife - published May 8, 2015
2. Cianfrocco MA, Leschziner AE
A sulfur-based transport pathway in Cu+-ATPases.
1. EMBO Rep. - published May 8, 2015
2. Mattle D, Zhang L, Sitsel O, Pedersen LT, Moncelli MR, Tadini-Buoninsegni F, Gourdon P, Rees DC, Nissen P, Meloni G
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC.
1. Mol. Cell - published May 7, 2015
2. Thomas LR, Wang Q, Grieb BC, Phan J, Foshage AM, Sun Q, Olejniczak ET, Clark T, Dey S, Lorey S, Alicie B, Howard GC, Cawthon B, Ess KC, Eischen CM, Zhao Z, Fesik SW, Tansey WP
ATP-dependent effector-like functions of RIG-I-like receptors.
1. Mol. Cell - published May 7, 2015
2. Yao H, Dittmann M, Peisley A, Hoffmann HH, Gilmore RH, Schmidt T, Schmid-Burgk JL, Hornung V, Rice CM, Hur S
REdiii: a pipeline for automated structure solution.
1. Acta Crystallogr. D Biol. Crystallogr. - published May 7, 2015
2. Bohn MF, Schiffer CA
A Transporter Motor Taken Apart: Flexibility in the Nucleotide Binding Domains of a Heterodimeric ABC Exporter.
1. Biochemistry - published May 7, 2015
2. Bukowska MA, Hohl M, Geertsma ER, Hürlimann LM, Grütter MG, Seeger MA
Fractional killing arises from cell-to-cell variability in overcoming a caspase activity threshold.
1. Mol. Syst. Biol. - published May 7, 2015
2. Roux J, Hafner M, Bandara S, Sims JJ, Hudson H, Chai D, Sorger PK
Structure and Assembly of Group B Streptococcus Pilus 2b Backbone Protein.
1. PLoS ONE - published May 6, 2015
2. Cozzi R, Malito E, Lazzarin M, Nuccitelli A, Castagnetti A, Bottomley MJ, Margarit I, Maione D, Rinaudo CD
How RIG-I like receptors activate MAVS.
1. Curr Opin Virol - published May 6, 2015
2. Wu B, Hur S
Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase Eta in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2'-deoxyguanosine.
1. J. Biol. Chem. - published May 6, 2015
2. Su Y, Patra A, Harp JM, Egli M, Guengerich FP
EGFR mutations and resistance to Irreversible pyrimidine based EGFR inhibitors.
1. Clin. Cancer Res. - published May 6, 2015
2. Ercan D, Choi HG, Yun CH, Capelletti M, Xie T, Eck MJ, Gray NS, Jänne PA
Brains, genes, and primates.
1. Neuron - published May 6, 2015
2. Izpisua Belmonte JC, Callaway EM, Caddick SJ, Churchland P, Feng G, Homanics GE, Lee KF, Leopold DA, Miller CT, Mitchell JF, Mitalipov S, Moutri AR, Movshon JA, Okano H, Reynolds JH, Ringach D, Sejnowski TJ, Silva AC, Strick PL, Wu J, Zhang F
Solution structure of the Atg1 complex: implications for the architecture of the phagophore assembly site.
1. Structure - published May 5, 2015
2. Köfinger J, Ragusa MJ, Lee IH, Hummer G, Hurley JH
FlaF Is a β-Sandwich Protein that Anchors the Archaellum in the Archaeal Cell Envelope by Binding the S-Layer Protein.
1. Structure - published May 5, 2015
2. Banerjee A, Tsai CL, Chaudhury P, Tripp P, Arvai AS, Ishida JP, Tainer JA, Albers SV
The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization.
1. Structure - published May 5, 2015
2. Bohn MF, Shandilya SM, Silvas TV, Nalivaika EA, Kouno T, Kelch BA, Ryder SP, Kurt-Yilmaz N, Somasundaran M, Schiffer CA
Integrative Modeling of Biomolecular Complexes: HADDOCKing with Cryo-Electron Microscopy Data.
1. Structure - published May 5, 2015
2. van Zundert GC, Melquiond AS, Bonvin AM
The selective autophagy receptor p62 forms a flexible filamentous helical scaffold.
1. Cell Rep - published May 5, 2015
2. Ciuffa R, Lamark T, Tarafder AK, Guesdon A, Rybina S, Hagen WJ, Johansen T, Sachse C
Predicting Peptide-mediated interactions on a genome-wide scale.
1. PLoS Comput. Biol. - published May 5, 2015
2. Chen TS, Petrey D, Garzon JI, Honig B
Powering Brain Power: GLUT1 and the Era of Structure Based Human Transporter Biology.
1. Natl Sci Rev - published May 5, 2015
2. Rees DC
Integration of kinetic isotope effect analyses to elucidate ribonuclease mechanism.
1. Biochim. Biophys. Acta - published May 5, 2015
2. Harris ME, Piccirilli JA, York DM
Towards understanding nuclear pore complex architecture and dynamics in the age of integrative structural analysis.
1. Curr. Opin. Cell Biol. - published May 5, 2015
2. Hurt E, Beck M
Spinach RNA aptamer detects lead(ii) with high selectivity.
1. Chem. Commun. (Camb.) - published May 5, 2015
2. DasGupta S, Shelke SA, Li NS, Piccirilli JA
AppCiter: A Web Application for Increasing Rates and Accuracy of Scientific Software Citation.
1. Structure - published May 5, 2015
2. Socias SM, Morin A, Timony MA, Sliz P
Peptide Binding to a PDZ Domain by Electrostatic Steering via Nonnative Salt Bridges.
1. Biophys. J. - published May 5, 2015
2. Blöchliger N, Xu M, Caflisch A
SIRT1 deacetylates RORγt and enhances Th17 cell generation.
1. J Exp Med - published May 4, 2015
2. Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, Xiao C, Littman DR, Ott M, Verdin E
Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation.
1. Nat. Struct. Mol. Biol. - published May 4, 2015
2. Yang B, Stjepanovic G, Shen Q, Martin A, Hurley JH
Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site.
1. Proc. Natl. Acad. Sci. U.S.A. - published May 4, 2015
2. Mazhab-Jafari MT, Marshall CB, Smith MJ, Gasmi-Seabrook GM, Stathopulos PB, Inagaki F, Kay LE, Neel BG, Ikura M
Disruption of Wnt/β-catenin signaling and telomeric shortening are inextricable consequences of tankyrase inhibition in human cells.
1. Mol. Cell. Biol. - published May 4, 2015
2. Kulak O, Chen H, Holohan B, Wu X, He H, Borek D, Otwinowski Z, Yamaguchi K, Garofalo LA, Ma Z, Wright W, Chen C, Shay JW, Zhang X, Lum L
CD4 mimetics sensitize HIV-1-infected cells to ADCC.
1. Proc. Natl. Acad. Sci. U.S.A. - published May 4, 2015
2. Richard J, Veillette M, Brassard N, Iyer SS, Roger M, Martin L, Pazgier M, Schön A, Freire E, Routy JP, Smith AB, Park J, Jones DM, Courter JR, Melillo BN, Kaufmann DE, Hahn BH, Permar SR, Haynes BF, Madani N, Sodroski JG, Finzi A
A Family of Tetraspans Organizes Cargo for Sorting into Multivesicular Bodies.
1. Dev. Cell - published May 4, 2015
2. MacDonald C, Payne JA, Aboian M, Smith W, Katzmann DJ, Piper RC
Dynamic structures in DNA damage responses & cancer.
1. Prog. Biophys. Mol. Biol. - published May 3, 2015
2. Tainer JA
Short LOV Proteins in Methylocystis Reveal Insight into LOV Domain Photocycle Mechanisms.
1. PLoS ONE - published May 2, 2015
2. El-Arab KK, Pudasaini A, Zoltowski BD
Functional assembly of accessory optic system circuitry critical for compensatory eye movements.
1. Neuron - published May 2, 2015
2. Sun LO, Brady CM, Cahill H, Al-Khindi T, Sakuta H, Dhande OS, Noda M, Huberman AD, Nathans J, Kolodkin AL
The αvβ1 integrin plays a critical in vivo role in tissue fibrosis.
1. Sci Transl Med - published May 2, 2015
2. Reed NI, Jo H, Chen C, Tsujino K, Arnold TD, DeGrado WF, Sheppard D
Cryo-EM: A Unique Tool for the Visualization of Macromolecular Complexity.
1. Mol Cell - published May 2, 2015
2. Nogales E, Scheres SH
The cancer cell map initiative: defining the hallmark networks of cancer.
1. Mol Cell - published May 2, 2015
2. Krogan NJ, Lippman S, Agard DA, Ashworth A, Ideker T
An automatic tool to analyze and cluster macromolecular conformations based on self-organizing maps.
1. Bioinformatics - published May 1, 2015
2. Bouvier G, Desdouits N, Ferber M, Blondel A, Nilges M
Functional Siglec lectin domains from soluble expression in the cytoplasm of Escherichia coli.
1. Protein Expr Purif - published May 1, 2015
2. Pröpster JM, Yang F, Ernst B, Allain FH, Schubert M
Engineered high-affinity nanobodies recognizing staphylococcal Protein A and suitable for native isolation of protein complexes.
1. Anal Biochem - published May 1, 2015
2. Fridy PC, Thompson MK, Ketaren NE, Rout MP
Broad-range inhibition of enterovirus replication by OSW-1, a natural compound targeting OSBP.
1. Antiviral Res - published May 1, 2015
2. Albulescu L, Strating JR, Thibaut HJ, van der Linden L, Shair MD, Neyts J, van Kuppeveld FJ
Targeting of the hydrophobic metabolome by pathogens.
1. Traffic - published May 1, 2015
2. Helms JB, Kaloyanova DV, Strating JR, van Hellemond JJ, van der Schaar HM, Tielens AG, van Kuppeveld FJ, Brouwers JF
SubspaceEM: A fast maximum-a-posteriori algorithm for cryo-EM single particle reconstruction.
1. J Struct Biol - published May 1, 2015
2. Dvornek NC, Sigworth FJ, Tagare HD
Integrin engagement by the helical RGD motif of the Helicobacter pylori CagL protein is regulated by pH-induced displacement of a neighboring helix.
1. J Biol Chem - published May 1, 2015
2. Bonsor DA, Pham KT, Beadenkopf R, Diederichs K, Haas R, Beckett D, Fischer W, Sundberg EJ
High-throughput functional genomics using CRISPR-Cas9.
1. Nat Rev Genet - published May 1, 2015
2. Shalem O, Sanjana NE, Zhang F
Spectroscopic and Computational Investigation of the H155A Variant of Cysteine Dioxygenase: Geometric and Electronic Consequences of a Third-Sphere Amino Acid Substitution.
1. Biochemistry - published May 1, 2015
2. Blaesi EJ, Fox BG, Brunold TC
Structural Characterization of LRRK2 Inhibitors.
1. J. Med. Chem. - published May 1, 2015
2. Gilsbach BK, Messias AC, Ito G, Sattler M, Alessi DR, Wittinghofer A, Kortholt A
Determination of small crystal structures from a minimum set of diffraction intensities by homotopy continuation.
1. Acta Crystallogr A Found Adv - published May 1, 2015
2. Leggas D, Tsodikov OV
An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation.
1. Cancer Metab - published May 1, 2015
2. Mattaini KR, Brignole EJ, Kini M, Davidson SM, Fiske BP, Drennan CL, Vander Heiden MG
Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection.
1. PLoS Pathog. - published May 1, 2015
2. Lin AE, Beasley FC, Olson J, Keller N, Shalwitz RA, Hannan TJ, Hultgren SJ, Nizet V
CRISPR germline engineering--the community speaks.
1. Nat Biotechnol - published May 1, 2015
2. Bosley KS, Botchan M, Bredenoord AL, Carroll D, Charo RA, Charpentier E, Cohen R, Corn J, Doudna J, Feng G, Greely HT, Isasi R, Ji W, Kim JS, Knoppers B, Lanphier E, Li J, Lovell-Badge R, Martin GS, Moreno J, Naldini L, Pera M, Perry AC, Venter JC, Zhang F, Zhou Q
Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic.
1. Elife - published May 1, 2015
2. Mendez AS, Alfaro J, Morales-Soto MA, Dar AC, McCullagh E, Gotthardt K, Li H, Acosta-Alvear D, Sidrauski C, Korennykh AV, Bernales S, Shokat KM, Walter P
Identification of the minimal binding region of a Plasmodium falciparum IgM binding PfEMP1 domain.
1. Mol Biochem Parasitol - published May 1, 2015
2. Semblat JP, Ghumra A, Czajkowsky DM, Wallis R, Mitchell DA, Raza A, Rowe JA
Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.
1. Sci Adv - published May 1, 2015
2. Li W, Liu Z, Koripella RK, Langlois R, Sanyal S, Frank J