Member Publications

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140 Member Publications for April 2015

Surviving apoptosis: life-death signaling in single cells.
1. Trends Cell Biol. - published April 30, 2015
2. Flusberg DA, Sorger PK
Crystal structure of the protein At3g01520, a eukaryotic universal stress protein-like protein from Arabidopsis thaliana in complex with AMP.
1. Proteins - published April 30, 2015
2. Kim do J, Bitto E, Bingman CA, Kim HJ, Han BW, Phillips GN
Phosphorylation propels p31(comet) for mitotic exit.
1. Cell Cycle - published April 30, 2015
2. Choi E, Yu H
FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic-pituitary-adrenal axis.
1. Nat Commun - published April 29, 2015
2. Perry RJ, Lee S, Ma L, Zhang D, Schlessinger J, Shulman GI
Hepatic ADC map as an adjunct to conventional abdominal MRI to evaluate hepatic fibrotic and clinical cirrhotic severity in biliary atresia patients.
1. Eur Radiol - published April 29, 2015
2. Peng SS, Jeng YM, Hsu WM, Yang JC, Ho MC
HCoV-HKU1 Spike protein uses O-acetylated sialic acid as an attachment receptor determinant and employs HE protein as a receptor-destroying enzyme.
1. J. Virol. - published April 29, 2015
2. Huang X, Dong W, Milewska A, Golda A, Qi Y, Zhu QK, Marasco WA, Baric RS, Sims AC, Pyrc K, Li W, Sui J
CTF Challenge: Result summary.
1. J. Struct. Biol. - published April 28, 2015
2. Marabini R, Carragher B, Chen S, Chen J, Cheng A, Downing KH, Frank J, Grassucci RA, Bernard Heymann J, Jiang W, Jonic S, Liao HY, Ludtke SJ, Patwari S, Piotrowski AL, Quintana A, Sorzano CO, Stahlberg H, Vargas J, Voss NR, Chiu W, Carazo JM
Functional reconstitution of Drosophila melanogaster NMJ glutamate receptors.
1. Proc. Natl. Acad. Sci. U.S.A. - published April 27, 2015
2. Han TH, Dharkar P, Mayer ML, Serpe M
Missense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activation.
1. Proc. Natl. Acad. Sci. U.S.A. - published April 27, 2015
2. Maus M, Jairaman A, Stathopulos PB, Muik M, Fahrner M, Weidinger C, Benson M, Fuchs S, Ehl S, Romanin C, Ikura M, Prakriya M, Feske S
Human NOTCH2 is resistant to ligand independent activation by metalloprotease Adam17.
1. J. Biol. Chem. - published April 27, 2015
2. Habets RA, Groot AJ, Yahyanejad S, Tiyanont K, Blacklow SC, Vooijs M
A novel RNA binding surface of the TAM domain of TIP5/BAZ2A mediates epigenetic regulation of rRNA genes.
1. Nucleic Acids Res. - published April 27, 2015
2. Anosova I, Melnik S, Tripsianes K, Kateb F, Grummt I, Sattler M
RWD Domain as an E2 (Ubc9)-Interaction Module.
1. J. Biol. Chem. - published April 27, 2015
2. Alontaga AY, Ambaye ND, Li YJ, Vega R, Chen CH, Bzymek KP, Williams JC, Hu W, Chen Y
A novel role for PilNO in type IV pilus retraction revealed by alignment subcomplex mutations.
1. J. Bacteriol. - published April 27, 2015
2. Leighton TL, Dayalani N, Sampaleanu LM, Howell PL, Burrows LL
Uncovering the Role of Sgf73 in Maintaining SAGA Deubiquitinating Module Structure and Activity.
1. J. Mol. Biol. - published April 24, 2015
2. Yan M, Wolberger C
Allosteric Coupling via Distant Disorder-to-Order Transitions.
1. J. Mol. Biol. - published April 24, 2015
2. Eginton C, Cressman WJ, Bachas S, Wade H, Beckett D
LucY: A Versatile New Fluorescent Reporter Protein.
1. PLoS ONE - published April 24, 2015
2. Auldridge ME, Cao H, Sen S, Franz LP, Bingman CA, Yennamalli RM, Phillips GN, Mead D, Steinmetz EJ
V-cGAPs: attenuators of 3'3'-cGAMP signaling.
1. Cell Res. - published April 24, 2015
2. Gao P, Patel DJ
A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1.
1. PLoS One - published April 24, 2015
2. Clifton MC, Dranow DM, Leed A, Fulroth B, Fairman JW, Abendroth J, Atkins KA, Wallace E, Fan D, Xu G, Ni ZJ, Daniels D, Van Drie J, Wei G, Burgin AB, Golub TR, Hubbard BK, Serrano-Wu MH
Store-operated calcium entry: Mechanisms and modulation.
1. Biochem. Biophys. Res. Commun. - published April 24, 2015
2. Hogan PG, Rao A
Calmodulin and STIM proteins: Two major calcium sensors in the cytoplasm and endoplasmic reticulum.
1. Biochem. Biophys. Res. Commun. - published April 24, 2015
2. Marshall CB, Nishikawa T, Osawa M, Stathopulos PB, Ikura M
ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes.
1. Nature - published April 23, 2015
2. Diao J, Liu R, Rong Y, Zhao M, Zhang J, Lai Y, Zhou Q, Wilz LM, Li J, Vivona S, Pfuetzner RA, Brunger AT, Zhong Q
Structural biology: Pain-sensing TRPA1 channel resolved.
1. Nature - published April 23, 2015
2. Clapham DE
Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
1. Cell - published April 23, 2015
2. Wu X, Zhang Z, Schramm CA, Joyce MG, Kwon YD, Zhou T, Sheng Z, Zhang B, O'Dell S, McKee K, Georgiev IS, Chuang GY, Longo NS, Lynch RM, Saunders KO, Soto C, Srivatsan S, Yang Y, Bailer RT, Louder MK, NISC Comparative Sequencing Program, Mullikin JC, Connors M, Kwong PD, Mascola JR, Shapiro L
Neutralization Properties of Simian Immunodeficiency Viruses Infecting Chimpanzees and Gorillas.
1. MBio - published April 23, 2015
2. Barbian HJ, Decker JM, Bibollet-Ruche F, Galimidi RP, West AP, Learn GH, Parrish NF, Iyer SS, Li Y, Pace CS, Song R, Huang Y, Denny TN, Mouquet H, Martin L, Acharya P, Zhang B, Kwong PD, Mascola JR, Verrips CT, Strokappe NM, Rutten L, McCoy LE, Weiss RA, Brown CS, Jackson R, Silvestri G, Connors M, Burton DR, Shaw GM, Nussenzweig MC, Bjorkman PJ, Ho DD, Farzan M, Hahn BH
A Primer to Single-Particle Cryo-Electron Microscopy.
1. Cell - published April 23, 2015
2. Cheng Y, Grigorieff N, Penczek PA, Walz T
Cancer: An essential passenger with p53.
1. Nature - published April 22, 2015
2. Bradner JE
NMRFAM-SDF: a protein structure determination framework.
1. J. Biomol. NMR - published April 22, 2015
2. Dashti H, Lee W, Tonelli M, Cornilescu CC, Cornilescu G, Assadi-Porter FM, Westler WM, Eghbalnia HR, Markley JL
Gene Expression by Mouse Inner Ear Hair Cells during Development.
1. J. Neurosci. - published April 22, 2015
2. Scheffer DI, Shen J, Corey DP, Chen ZY
An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions.
1. Cell Rep - published April 21, 2015
2. Leung DW, Borek D, Luthra P, Binning JM, Anantpadma M, Liu G, Harvey IB, Su Z, Endlich-Frazier A, Pan J, Shabman RS, Chiu W, Davey RA, Otwinowski Z, Basler CF, Amarasinghe GK
A Functional Interplay between Human Immunodeficiency Virus Type 1 Protease Residues 77 and 93 Involved in Differential Regulation of Precursor Autoprocessing and Mature Protease Activity.
1. PLoS ONE - published April 21, 2015
2. Counts CJ, Ho PS, Donlin MJ, Tavis JE, Chen C
Live-cell imaging of actin dynamics reveals mechanisms of stereocilia length regulation in the inner ear.
1. Nat Commun - published April 21, 2015
2. Drummond MC, Barzik M, Bird JE, Zhang DS, Lechene CP, Corey DP, Cunningham LL, Friedman TB
Length regulation of mechanosensitive stereocilia depends on very slow actin dynamics and filament-severing proteins.
1. Nat Commun - published April 21, 2015
2. Narayanan P, Chatterton P, Ikeda A, Ikeda S, Corey DP, Ervasti JM, Perrin BJ
VIH2 Regulates the Synthesis of Inositol Pyrophosphate InsP8 and Jasmonate-Dependent Defenses in Arabidopsis.
1. Plant Cell - published April 21, 2015
2. Laha D, Johnen P, Azevedo C, Dynowski M, Weiß M, Capolicchio S, Mao H, Iven T, Steenbergen M, Freyer M, Gaugler P, de Campos MK, Zheng N, Feussner I, Jessen HJ, Van Wees SC, Saiardi A, Schaaf G
TREM-2 promotes macrophage survival and lung disease after respiratory viral infection.
1. J. Exp. Med. - published April 20, 2015
2. Wu K, Byers DE, Jin X, Agapov E, Alexander-Brett J, Patel AC, Cella M, Gilfilan S, Colonna M, Kober DL, Brett TJ, Holtzman MJ
An organized co-assembly of clathrin adaptors is essential for endocytosis.
1. Dev. Cell - published April 20, 2015
2. Skruzny M, Desfosses A, Prinz S, Dodonova SO, Gieras A, Uetrecht C, Jakobi AJ, Abella M, Hagen WJ, Schulz J, Meijers R, Rybin V, Briggs JA, Sachse C, Kaksonen M
Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism.
1. Biosci. Rep. - published April 20, 2015
2. Haslbeck V, Drazic A, Eckl JM, Alte F, Helmuth M, Popowicz G, Schmidt W, Braun F, Weiwad M, Fischer G, Gemmecker G, Sattler M, Striggow F, Groll M, Richter K
A variable DNA recognition site organization establishes the LiaR-mediated cell envelope stress response of enterococci to daptomycin.
1. Nucleic Acids Res. - published April 19, 2015
2. Davlieva M, Shi Y, Leonard PG, Johnson TA, Zianni MR, Arias CA, Ladbury JE, Shamoo Y
Structural Effects of Protein Aging: Terminal Marking by Deamidation in Human Triosephosphate Isomerase.
1. PLoS ONE - published April 18, 2015
2. de la Mora-de la Mora I, Torres-Larios A, Enríquez-Flores S, Méndez ST, Castillo-Villanueva A, Gómez-Manzo S, López-Velázquez G, Marcial-Quino J, Torres-Arroyo A, García-Torres I, Reyes-Vivas H, Oria-Hernández J
Signaling mechanism of the netrin-1 receptor DCC in axon guidance.
1. Prog. Biophys. Mol. Biol. - published April 18, 2015
2. Finci L, Zhang Y, Meijers R, Wang JH
The catalytic domains of Clostridium sordellii lethal toxin and related large clostridial glucosylating toxins specifically recognize the negatively charged phospholipids phosphatidylserine and phosphatidic acid.
1. Cell. Microbiol. - published April 18, 2015
2. Varela Chavez C, Hoos S, Haustant GM, Chenal A, England P, Blondel A, Pauillac S, Lacy DB, Popoff MR
Conformational flexibility and subunit arrangement of the modular yeast spt-ada-gcn5 acetyltransferase complex.
1. J. Biol. Chem. - published April 17, 2015
2. Setiaputra D, Ross JD, Lu S, Cheng DT, Dong MQ, Yip CK
Discovery of Tricyclic Indoles That Potently Inhibit Mcl-1 Using Fragment-Based Methods and Structure-Based Design.
1. J. Med. Chem. - published April 17, 2015
2. Burke JP, Bian Z, Shaw S, Zhao B, Goodwin CM, Belmar J, Browning CF, Vigil D, Friberg A, Camper DV, Rossanese OW, Lee T, Olejniczak ET, Fesik SW
The hierarchical structural architecture of inflammasomes, supramolecular inflammatory machines.
1. Curr. Opin. Struct. Biol. - published April 17, 2015
2. Hauenstein AV, Zhang L, Wu H
Methyl-specific isotopic labeling: a molecular tool box for solution NMR studies of large proteins.
1. Curr. Opin. Struct. Biol. - published April 17, 2015
2. Kerfah R, Plevin MJ, Sounier R, Gans P, Boisbouvier J
Inferring causal metabolic signals that regulate the dynamic TORC1-dependent transcriptome.
1. Mol. Syst. Biol. - published April 17, 2015
2. Oliveira AP, Dimopoulos S, Busetto AG, Christen S, Dechant R, Falter L, Haghir Chehreghani M, Jozefczuk S, Ludwig C, Rudroff F, Schulz JC, González A, Soulard A, Stracka D, Aebersold R, Buhmann JM, Hall MN, Peter M, Sauer U, Stelling J
HOTAIR Forms an Intricate and Modular Secondary Structure.
1. Mol. Cell - published April 16, 2015
2. Somarowthu S, Legiewicz M, Chillón I, Marcia M, Liu F, Pyle AM
PTEN functions by recruitment to cytoplasmic vesicles.
1. Mol. Cell - published April 16, 2015
2. Naguib A, Bencze G, Cho H, Zheng W, Tocilj A, Elkayam E, Faehnle CR, Jaber N, Pratt CP, Chen M, Zong WX, Marks MS, Joshua-Tor L, Pappin DJ, Trotman LC
Rheostat re-wired: alternative hypotheses for the control of thioredoxin reduction potentials.
1. PLoS ONE - published April 16, 2015
2. Bewley KD, Dey M, Bjork RE, Mitra S, Chobot SE, Drennan CL, Elliott SJ
Antibodies: validate recombinants once.
1. Nature - published April 16, 2015
2. Bradbury AM, Plückthun A
Near-atomic cryo-EM structure of the helical measles virus nucleocapsid.
1. Science - published April 16, 2015
2. Gutsche I, Desfosses A, Effantin G, Ling WL, Haupt M, Ruigrok RW, Sachse C, Schoehn G
Genetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1.
1. RNA - published April 16, 2015
2. Schwer B, Ghosh A, Sanchez AM, Lima CD, Shuman S
NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy.
1. Bioinformatics - published April 15, 2015
2. Lee W, Tonelli M, Markley JL
Personalized Biochemistry and Biophysics.
1. Biochemistry - published April 15, 2015
2. Kroncke BM, Vanoye CG, Meiler J, George AL, Sanders CR
Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD.
1. Hum. Mol. Genet. - published April 15, 2015
2. Zhou X, Fan LX, Peters DJ, Trudel M, Bradner JE, Li X
VFV as a new effective CYP51 structure-derived drug candidate for Chagas disease and visceral leishmaniasis.
1. J. Infect. Dis. - published April 15, 2015
2. Lepesheva GI, Hargrove TY, Rachakonda G, Wawrzak Z, Pomel S, Cojean S, Nde PN, Nes WD, Locuson CW, Calcutt MW, Waterman MR, Daniels JS, Loiseau PM, Villalta F
Correlating RANK ligand/RANK binding kinetics with osteoclast formation and function.
1. J. Cell. Biochem. - published April 14, 2015
2. Warren JT, Zou W, Decker CE, Rohatgi N, Nelson CA, Fremont DH, Teitelbaum SL
Structure of the yeast Bre1 RING domain.
1. Proteins - published April 14, 2015
2. Kumar P, Wolberger C
Viral membrane fusion.
1. Virology - published April 14, 2015
2. Harrison SC
Accurate membrane tracing in three-dimensional reconstructions from electron cryotomography data.
1. Ultramicroscopy - published April 13, 2015
2. Page C, Hanein D, Volkmann N
Desformylflustrabromine (dFBr) and [3H]dFBr-labeled Binding Sites in a Nicotinic Acetylcholine Receptor.
1. Mol. Pharmacol. - published April 13, 2015
2. Hamouda AK, Wang ZJ, Stewart DS, Jain AD, Glennon RA, Cohen JB
Perspective on computational and structural aspects of kinase discovery from IPK2014.
1. Biochim. Biophys. Acta - published April 12, 2015
2. Martin E, Knapp S, Engh RA, Moebitz H, Varin T, Roux B, Meiler J, Berdini V, Baumann A, Vieth M
Analysis of immunoglobulin transcripts and hypermutation following SHIVAD8 infection and protein-plus-adjuvant immunization.
1. Nat Commun - published April 11, 2015
2. Francica JR, Sheng Z, Zhang Z, Nishimura Y, Shingai M, Ramesh A, Keele BF, Schmidt SD, Flynn BJ, Darko S, Lynch RM, Yamamoto T, Matus-Nicodemos R, Wolinsky D, NISC Comparative Sequencing Program, Nason M, Valiante NM, Malyala P, De Gregorio E, Barnett SW, Singh M, O'Hagan DT, Koup RA, Mascola JR, Martin MA, Kepler TB, Douek DC, Shapiro L, Seder RA
Zinc regulates a switch between primary and alternative S18 ribosomal proteins in Mycobacterium tuberculosis.
1. Mol. Microbiol. - published April 11, 2015
2. Prisic S, Hwang H, Dow A, Barnaby O, Pan TS, Lonzanida JA, Chazin WJ, Steen H, Husson RN
Rapid and facile recombinant expression of bovine rhodopsin in HEK293S GnTI(-) cells using a PiggyBac inducible system.
1. Meth. Enzymol. - published April 11, 2015
2. Caro LN, Li Z, Balo AR, Van Eps N, Rini JM, Ernst OP
Structural Modeling of a Novel CAPN5 Mutation that Causes Uveitis and Neovascular Retinal Detachment.
1. PLoS ONE - published April 10, 2015
2. Bassuk AG, Yeh S, Wu S, Martin DF, Tsang SH, Gakhar L, Mahajan VB
Picodiscs for Facile Protein-Glycolipid Interaction Analysis.
1. Anal. Chem. - published April 9, 2015
2. Leney AC, Rezaei Darestani R, Li J, Nikjah S, Kitova EN, Zou C, Cairo CW, Xiong ZJ, Privé GG, Klassen JS
In vivo genome editing using Staphylococcus aureus Cas9.
1. Nature - published April 9, 2015
2. Ran FA, Cong L, Yan WX, Scott DA, Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F
Urinary tract infections: epidemiology, mechanisms of infection and treatment options.
1. Nat. Rev. Microbiol. - published April 9, 2015
2. Flores-Mireles AL, Walker JN, Caparon M, Hultgren SJ
Expression platforms for producing eukaryotic proteins: a comparison of E. coli cell-based and wheat germ cell-free synthesis, affinity and solubility tags, and cloning strategies.
1. J. Struct. Funct. Genomics - published April 9, 2015
2. Aceti DJ, Bingman CA, Wrobel RL, Frederick RO, Makino S, Nichols KW, Sahu SC, Bergeman LF, Blommel PG, Cornilescu CC, Gromek KA, Seder KD, Hwang S, Primm JG, Sabat G, Vojtik FC, Volkman BF, Zolnai Z, Phillips GN, Markley JL, Fox BG
Real-time visualization of nanoparticles interacting with glioblastoma stem cells.
1. Nano Lett. - published April 8, 2015
2. Pohlmann ES, Patel K, Guo S, Dukes MJ, Sheng Z, Kelly DF
Effects of the I559P gp41 Change on the Conformation and Function of the Human Immunodeficiency Virus (HIV-1) Membrane Envelope Glycoprotein Trimer.
1. PLoS ONE - published April 8, 2015
2. Alsahafi N, Debbeche O, Sodroski J, Finzi A
Structural and Functional Roles of Glycosylation in Fungal Laccase from Lentinus sp.
1. PLoS ONE - published April 8, 2015
2. Maestre-Reyna M, Liu WC, Jeng WY, Lee CC, Hsu CA, Wen TN, Wang AH, Shyur LF
The crystal structure of phosphorylated MAPK13 reveals common structural features and differences in p38 MAPK family activation.
1. Acta Crystallogr. D Biol. Crystallogr. - published April 8, 2015
2. Yurtsever Z, Scheaffer SM, Romero AG, Holtzman MJ, Brett TJ
Capture and X-ray diffraction studies of protein microcrystals in a microfluidic trap array.
1. Acta Crystallogr. D Biol. Crystallogr. - published April 8, 2015
2. Lyubimov AY, Murray TD, Koehl A, Araci IE, Uervirojnangkoorn M, Zeldin OB, Cohen AE, Soltis SM, Baxter EL, Brewster AS, Sauter NK, Brunger AT, Berger JM
Structure of the ABL2/ARG kinase in complex with dasatinib.
1. Acta Crystallogr F Struct Biol Commun - published April 8, 2015
2. Ha BH, Simpson MA, Koleske AJ, Boggon TJ
Wnt acylation and its functional implication in Wnt signalling regulation.
1. Biochem. Soc. Trans. - published April 8, 2015
2. Janda CY, Garcia KC
Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase: Structure of the Enzyme-Progesterone Substrate Complex and Rate-Limiting C-H Bond Cleavage.
1. J. Biol. Chem. - published April 8, 2015
2. Pallan PS, Wang C, Lei L, Yoshimoto FK, Auchus RJ, Waterman MR, Guengerich FP, Egli M
Cell-surface attachment of bacterial multi-enzyme complexes involves highly dynamic protein-protein anchors.
1. J. Biol. Chem. - published April 8, 2015
2. Cameron K, Najmudin S, Alves VD, Bayer EA, Smith SP, Bule P, Waller H, Ferreira LM, Gilbert HJ, Fontes CM
Signaling, regulation and specificity of the type II p21-activated kinases.
1. J. Biol. Chem. - published April 8, 2015
2. Ha BH, Morse EM, Turk BE, Boggon TJ
Structural Insight into MtmC, a Bifunctional Ketoreductase-Methyltransferase Involved in the Assembly of the Mithramycin Trisaccharide Chain.
1. Biochemistry - published April 7, 2015
2. Chen JM, Hou C, Wang G, Tsodikov OV, Rohr J
Structures of C1q-like proteins reveal unique features among the C1q/TNF superfamily.
1. Structure - published April 7, 2015
2. Ressl S, Vu BK, Vivona S, Martinelli DC, Südhof TC, Brunger AT
Structural basis for molecular discrimination by a 3',3'-cGAMP sensing riboswitch.
1. Cell Rep - published April 7, 2015
2. Ren A, Wang XC, Kellenberger CA, Rajashankar KR, Jones RA, Hammond MC, Patel DJ
Structural mechanisms of DNA binding and unwinding in bacterial RecQ helicases.
1. Proc. Natl. Acad. Sci. U.S.A. - published April 7, 2015
2. Manthei KA, Hill MC, Burke JE, Butcher SE, Keck JL
Symportin 1 chaperones 5S RNP assembly during ribosome biogenesis by occupying an essential rRNA-binding site.
1. Nat Commun - published April 7, 2015
2. Calviño FR, Kharde S, Ori A, Hendricks A, Wild K, Kressler D, Bange G, Hurt E, Beck M, Sinning I
A Nonapoptotic Role for BAX and BAK in Eicosanoid Metabolism.
1. ACS Chem. Biol. - published April 6, 2015
2. Zhang T, Walensky LD, Saghatelian A
Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm.
1. J. Exp. Med. - published April 6, 2015
2. Methot SP, Litzler LC, Trajtenberg F, Zahn A, Robert F, Pelletier J, Buschiazzo A, Magor BG, Di Noia JM
A role for protein kinase A in the Neurospora circadian clock by regulating WC-independent frequency transcription through phosphorylation of RCM-1.
1. Mol. Cell. Biol. - published April 6, 2015
2. Liu X, Li H, Liu Q, Niu Y, Hu Q, Deng H, Cha J, Wang Y, Liu Y, He Q
eIF3 targets cell-proliferation messenger RNAs for translational activation or repression.
1. Nature - published April 6, 2015
2. Lee AS, Kranzusch PJ, Cate JH
Specificity of the ModA11, ModA12 and ModD1 epigenetic regulator N6-adenine DNA methyltransferases of Neisseria meningitidis.
1. Nucleic Acids Res. - published April 6, 2015
2. Seib KL, Jen FE, Tan A, Scott AL, Kumar R, Power PM, Chen LT, Wu HJ, Wang AH, Hill DM, Luyten YA, Morgan RD, Roberts RJ, Maiden MC, Boitano M, Clark TA, Korlach J, Rao DN, Jennings MP
A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and β-Catenin In Vitro and In Vivo.
1. Dev. Cell - published April 6, 2015
2. Choi HJ, Loveless T, Lynch AM, Bang I, Hardin J, Weis WI
Membrane Flotation Assay.
1. Bio Protoc - published April 5, 2015
2. Vogt DA, Ott M
Crystal Structure of the FLT3 Kinase Domain Bound to the Inhibitor Quizartinib (AC220).
1. PLoS ONE - published April 4, 2015
2. Zorn JA, Wang Q, Fujimura E, Barros T, Kuriyan J
Epigenetics. Epigenetic inheritance uncoupled from sequence-specific recruitment.
1. Science - published April 3, 2015
2. Ragunathan K, Jih G, Moazed D
Re-visiting the trans insertion model for complexin clamping.
1. Elife - published April 3, 2015
2. Krishnakumar SS, Li F, Coleman J, Schauder CM, Kümmel D, Pincet F, Rothman JE, Reinisch KM
Defining a Two-Pronged Structural Model for PB1 Domain Interaction in Plant Auxin Responses.
1. J. Biol. Chem. - published April 3, 2015
2. Korasick DA, Chatterjee S, Tonelli M, Dashti H, Lee SG, Westfall CS, Fulton DB, Andreotti AH, Amarasinghe GK, Strader LC, Jez JM
Hotspots in an obligate homodimeric anticancer target. Structural and functional effects of interfacial mutations in human thymidylate synthase.
1. J Med Chem - published April 2, 2015
2. Salo-Ahen OM, Tochowicz A, Pozzi C, Cardinale D, Ferrari S, Boum Y, Mangani S, Stroud RM, Saxena P, Myllykallio H, Costi MP, Ponterini G, Wade RC
Bayesian model selection applied to the analysis of fluorescence correlation spectroscopy data of fluorescent proteins in vitro and in vivo.
1. Anal Chem - published April 2, 2015
2. Sun G, Guo SM, Teh C, Korzh V, Bathe M, Wohland T
Does ketamine target olfactory receptors in the brain?
1. Sci Signal - published April 2, 2015
2. Wolf S, Hatt H, Ernst OP
Heavy atom labeled nucleotides for measurement of kinetic isotope effects.
1. Biochim. Biophys. Acta - published April 2, 2015
2. Weissman BP, Li NS, York D, Harris M, Piccirilli JA
Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning.
1. Science - published April 2, 2015
2. Taylor DW, Zhu Y, Staals RH, Kornfeld JE, Shinkai A, van der Oost J, Nogales E, Doudna JA
The crystal structure of DR6 in complex with the amyloid precursor protein provides insight into death receptor activation.
1. Genes Dev. - published April 2, 2015
2. Xu K, Olsen O, Tzvetkova-Robev D, Tessier-Lavigne M, Nikolov DB
The complete structure of the 55S mammalian mitochondrial ribosome.
1. Science - published April 2, 2015
2. Greber BJ, Bieri P, Leibundgut M, Leitner A, Aebersold R, Boehringer D, Ban N
Next-generation sequencing reveals the biological significance of the N2,3-ethenoguanine lesion in vivo.
1. Nucleic Acids Res. - published April 2, 2015
2. Chang SC, Fedeles BI, Wu J, Delaney JC, Li D, Zhao L, Christov PP, Yau E, Singh V, Jost M, Drennan CL, Marnett LJ, Rizzo CJ, Levine SS, Guengerich FP, Essigmann JM
'Velcro' engineering of high-affinity CD47 Ectodomain as SIRPα antagonists that enhance antibody-dependent cellular phagocytosis.
1. J. Biol. Chem. - published April 2, 2015
2. Ho CC, Guo N, Sockolosky JT, Ring AM, Weiskopf K, Özkan E, Mori Y, Weissman IL, Garcia KC
Structure of the TRPA1 ion channel suggests regulatory mechanisms.
1. Nature - published April 2, 2015
2. Paulsen CE, Armache JP, Gao Y, Cheng Y, Julius D
Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion.
1. Cell - published April 2, 2015
2. Rosenberg OS, Dovala D, Li X, Connolly L, Bendebury A, Finer-Moore J, Holton J, Cheng Y, Stroud RM, Cox JS
Single-Particle Cryo-EM at Crystallographic Resolution.
1. Cell - published April 2, 2015
2. Cheng Y
Resonance assignment and secondary structure determination of full length human Dickkopf 4 (hDkk4), a secreted, disulphide-rich Wnt inhibitor protein.
1. Biomol NMR Assign - published April 1, 2015
2. Barkell AM, Holdsworth G, Waters LC, Veverka V, Slocombe PM, Muskett FW, Henry AJ, Robinson MK, Carr MD
A cleavable ligand column for the rapid isolation of large quantities of homogeneous and functional neurotensin receptor 1 variants from E. coli.
1. Protein Expr Purif - published April 1, 2015
2. Egloff P, Deluigi M, Heine P, Balada S, Plückthun A
Expression and purification of functional human glycogen synthase-1:glycogenin-1 complex in insect cells.
1. Protein Expr Purif - published April 1, 2015
2. Hunter RW, Zeqiraj E, Morrice N, Sicheri F, Sakamoto K
The chemical component dictionary: complete descriptions of constituent molecules in experimentally determined 3D macromolecules in the Protein Data Bank.
1. Bioinformatics - published April 1, 2015
2. Westbrook JD, Shao C, Feng Z, Zhuravleva M, Velankar S, Young J
50 years of protein acetylation: from gene regulation to epigenetics, metabolism and beyond.
1. Nat Rev Mol Cell Biol - published April 1, 2015
2. Verdin E, Ott M
Role of the clathrin adaptor PICALM in normal hematopoiesis and polycythemia vera pathophysiology.
1. Haematologica - published April 1, 2015
2. Ishikawa Y, Maeda M, Pasham M, Aguet F, Tacheva-Grigorova SK, Masuda T, Yi H, Lee SU, Xu J, Teruya-Feldstein J, Ericsson M, Mullally A, Heuser J, Kirchhausen T, Maeda T
Differential Effects of Tyrosine Kinase Inhibitors on Normal and Oncogenic EGFR Signaling and Downstream Effectors.
1. Mol Cancer Res - published April 1, 2015
2. Kim Y, Apetri M, Luo B, Settleman JE, Anderson KS
Structural Basis for Host Membrane Remodeling Induced by Protein 2B of Hepatitis A Virus.
1. J. Virol. - published April 1, 2015
2. Vives-Adrián L, Garriga D, Buxaderas M, Fraga J, Pereira PJ, Macedo-Ribeiro S, Verdaguer N
Influenza viruses with receptor-binding N1 neuraminidases occur sporadically in several lineages and show no attenuation in cell culture or mice.
1. J Virol - published April 1, 2015
2. Hooper KA, Crowe JE Jr, Bloom JD
Computational design and experimental characterization of peptides intended for pH-dependent membrane insertion and pore formation.
1. ACS Chem Biol - published April 1, 2015
2. Zhang Y, Bartz R, Grigoryan G, Bryant M, Aaronson J, Beck S, Innocent N, Klein L, Procopio W, Tucker T, Jadhav V, Tellers DM, DeGrado WF
H-NS and RNA polymerase: a love-hate relationship?
1. Curr Opin Microbiol - published April 1, 2015
2. Landick R, Wade JT, Grainger DC
Plasma corin decreases after coronary artery bypass graft surgery and is associated with postoperative heart failure: a pilot study.
1. J Cardiothorac Vasc Anesth - published April 1, 2015
2. Barnet CS, Liu X, Body SC, Collard CD, Shernan SK, Muehlschlegel JD, Jarolim P, Fox AA
Impaired cytokine expression, neutrophil infiltration and bacterial clearance in response to urinary tract infection in diabetic mice.
1. Pathog Dis - published April 1, 2015
2. Ozer A, Altuntas CZ, Bicer F, Izgi K, Hultgren SJ, Liu G, Daneshgari F
Imaging active urokinase plasminogen activator in prostate cancer.
1. Cancer Res - published April 1, 2015
2. LeBeau AM, Sevillano N, Markham K, Winter MB, Murphy ST, Hostetter DR, West J, Lowman H, Craik CS, VanBrocklin HF
Several residues within the N-terminal arm of vesicular stomatitis virus nucleoprotein play a critical role in protecting viral RNA from nuclease digestion.
1. Virology - published April 1, 2015
2. Chen L, Yan Q, Lu G, Hu Z, Zhang G, Zhang S, Ding B, Jiang Y, Zhong Y, Gong P, Chen M
Atomic-accuracy models from 4.5-Å cryo-electron microscopy data with density-guided iterative local refinement.
1. Nat Methods - published April 1, 2015
2. DiMaio F, Song Y, Li X, Brunner MJ, Xu C, Conticello V, Egelman E, Marlovits T, Cheng Y, Baker D
The structure of SpnF, a standalone enzyme that catalyzes [4 + 2] cycloaddition.
1. Nat Chem Biol - published April 1, 2015
2. Fage CD, Isiorho EA, Liu Y, Wagner DT, Liu HW, Keatinge-Clay AT
The twisted relation between Pnu and SWEET transporters.
1. Trends Biochem Sci - published April 1, 2015
2. Jaehme M, Guskov A, Slotboom DJ
HkRP3 is a microtubule-binding protein regulating lytic granule clustering and NK cell killing.
1. J Immunol - published April 1, 2015
2. Ham H, Huynh W, Schoon RA, Vale RD, Billadeau DD
RNA World research-still evolving.
1. RNA - published April 1, 2015
2. Cech TR
Fifty to 100 times the size!
1. RNA - published April 1, 2015
2. Allain FH
Targeting diverse protein-protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold.
1. Proc Natl Acad Sci U S A - published April 1, 2015
2. Checco JW, Kreitler DF, Thomas NC, Belair DG, Rettko NJ, Murphy WL, Forest KT, Gellman SH
ASH1 mRNP-core factors form stable complexes in absence of cargo RNA at physiological conditions.
1. RNA Biol - published April 1, 2015
2. Edelmann FT, Niedner A, Niessing D
Binding of Substrates to the Central Pore of the Vps4 ATPase is Autoinhibited by the Microtubule Interacting and Trafficking (MIT) Domain and Activated by MIT Interacting Motifs (MIMs).
1. J. Biol. Chem. - published April 1, 2015
2. Han H, Monroe N, Votteler J, Shakya B, Sundquist WI, Hill CP
14-3-3 Proteins Restrain the Exo1 Nuclease to Prevent Over-resection.
1. J. Biol. Chem. - published April 1, 2015
2. Chen X, Kim IK, Honaker Y, Paudyal SC, Koh WK, Sparks M, Li S, Piwnica-Worms H, Ellenberger T, You Z
Fatal autoimmunity in mice reconstituted with human hematopoietic stem cells encoding defective FOXP3.
1. Blood - published April 1, 2015
2. Goettel JA, Biswas S, Lexmond WS, Yeste A, Passerini L, Patel B, Yang S, Sun J, Ouahed J, Shouval DS, McCann KJ, Horwitz BH, Mathis D, Milford EL, Notarangelo LD, Roncarolo MG, Fiebiger E, Marasco WA, Bacchetta R, Quintana FJ, Pai SY, Klein C, Muise AM, Snapper SB
Molecular dynamics studies of modular polyketide synthase ketoreductase stereospecificity.
1. Biochemistry - published April 1, 2015
2. Mugnai ML, Shi Y, Keatinge-Clay AT, Elber R
Crystallization and preliminary X-ray characterization of the eukaryotic replication terminator Reb1-Ter DNA complex.
1. Acta Crystallogr F Struct Biol Commun - published April 1, 2015
2. Jaiswal R, Singh SK, Bastia D, Escalante CR
Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response.
1. Elife - published April 1, 2015
2. Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, Renslo AR, Walter P
Discovery of the glycogen phosphorylase-modulating activity of a resveratrol glucoside by using a virtual screening protocol optimized for solvation effects.
1. Planta Med - published April 1, 2015
2. Mavrokefalos N, Myrianthopoulos V, Chajistamatiou AS, Chrysina ED, Mikros E
A redox regulatory system critical for mycobacterial survival in macrophages and biofilm development.
1. PLoS Pathog - published April 1, 2015
2. Wolff KA, de la Peña AH, Nguyen HT, Pham TH, Amzel LM, Gabelli SB, Nguyen L
Molecular basis of sugar recognition by collectin-K1 and the effects of mutations associated with 3MC syndrome.
1. BMC Biol - published April 1, 2015
2. Venkatraman Girija U, Furze CM, Gingras AR, Yoshizaki T, Ohtani K, Marshall JE, Wallis AK, Schwaeble WJ, El-Mezgueldi M, Mitchell DA, Moody PC, Wakamiya N, Wallis R
Serine Resolvases.
1. Microbiol Spectr - published April 1, 2015
2. Rice PA