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104 Member Publications for July 2014

Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies.
1. Cell - published July 31, 2014
2. Gao F, Bonsignori M, Liao HX, Kumar A, Xia SM, Lu X, Cai F, Hwang KK, Song H, Zhou T, Lynch RM, Alam SM, Moody MA, Ferrari G, Berrong M, Kelsoe G, Shaw GM, Hahn BH, Montefiori DC, Kamanga G, Cohen MS, Hraber P, Kwong PD, Korber BT, Mascola JR, Kepler TB, Haynes BF
Marinopyrrole derivatives with sulfide spacers as selective disruptors of Mcl-1 binding to pro-apoptotic protein Bim.
1. Mar Drugs - published July 31, 2014
2. Cheng C, Liu Y, Balasis ME, Garner TP, Li J, Simmons NL, Berndt N, Song H, Pan L, Qin Y, Nicolaou KC, Gavathiotis E, Sebti SM, Li R
Host-directed antimicrobial drugs with broad-spectrum efficacy against intracellular bacterial pathogens.
1. MBio - published July 31, 2014
2. Czyż DM, Potluri LP, Jain-Gupta N, Riley SP, Martinez JJ, Steck TL, Crosson S, Shuman HA, Gabay JE
Carbohydrate-mimetic peptides for pan anti-tumor responses.
1. Front Immunol - published July 30, 2014
2. Kieber-Emmons T, Saha S, Pashov A, Monzavi-Karbassi B, Murali R
Discovery of Type II Inhibitors of TGFβ-Activated Kinase 1 (TAK1) and Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2).
1. J. Med. Chem. - published July 30, 2014
2. Tan L, Nomanbhoy T, Gurbani D, Patricelli M, Hunter J, Geng J, Herhaus L, Zhang J, Pauls E, Ham Y, Choi HG, Xie T, Deng X, Buhrlage SJ, Sim T, Cohen P, Sapkota G, Westover KD, Gray NS
Pyruvate formate-lyase interacts directly with the formate channel FocA to regulate formate translocation.
1. J. Mol. Biol. - published July 29, 2014
2. Doberenz C, Zorn M, Falke D, Nannemann D, Hunger D, Beyer L, Ihling CH, Meiler J, Sinz A, Sawers RG
Modification and periplasmic translocation of the biofilm exopolysaccharide poly-β-1,6-N-acetyl-D-glucosamine.
1. Proc. Natl. Acad. Sci. U.S.A. - published July 29, 2014
2. Little DJ, Li G, Ing C, DiFrancesco BR, Bamford NC, Robinson H, Nitz M, Pomès R, Howell PL
Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter.
1. Proc. Natl. Acad. Sci. U.S.A. - published July 29, 2014
2. Hohl M, Hürlimann LM, Böhm S, Schöppe J, Grütter MG, Bordignon E, Seeger MA
Use of E2~ubiquitin conjugates for the characterization of ubiquitin transfer by RING E3 ligases such as the inhibitor of apoptosis proteins.
1. Methods Enzymol - published July 29, 2014
2. Middleton AJ, Budhidarmo R, Day CL
Ultrastructure and complex polar architecture of the human pathogen Campylobacter jejuni.
1. Microbiologyopen - published July 29, 2014
2. Müller A, Beeby M, McDowall AW, Chow J, Jensen GJ, Clemons WM
Relative distribution of quadriceps head anatomical cross-sectional areas and volumes-Sensitivity to pain and to training intervention.
1. Ann. Anat. - published July 29, 2014
2. Sattler M, Dannhauer T, Ring-Dimitriou S, Sänger AM, Wirth W, Hudelmaier M, Eckstein F
Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2.
1. Nat. Struct. Mol. Biol. - published July 28, 2014
2. Guettou F, Quistgaard EM, Raba M, Moberg P, Löw C, Nordlund P
Improving the apo-state detergent stability of NTS1 with CHESS for pharmacological and structural studies.
1. Biochim. Biophys. Acta - published July 28, 2014
2. Scott DJ, Kummer L, Egloff P, Bathgate RA, Plückthun A
A sugar phosphatase regulates the methylerythritol phosphate (MEP) pathway in malaria parasites.
1. Nat Commun - published July 25, 2014
2. Guggisberg AM, Park J, Edwards RL, Kelly ML, Hodge DM, Tolia NH, Odom AR
2',6'-Dihalostyrylanilines, pyridines, and pyrimidines for the inhibition of the catalytic subunit of methionine S-adenosyltransferase-2.
1. J. Med. Chem. - published July 24, 2014
2. Sviripa VM, Zhang W, Balia AG, Tsodikov OV, Nickell JR, Gizard F, Yu T, Lee EY, Dwoskin LP, Liu C, Watt DS
Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA.
1. Nature - published July 24, 2014
2. Wasmuth EV, Januszyk K, Lima CD
G-quadruplexes are specifically recognized and distinguished by selected designed ankyrin repeat proteins.
1. Nucleic Acids Res. - published July 24, 2014
2. Scholz O, Hansen S, Plückthun A
Structure of a membrane-embedded prenyltransferase homologous to UBIAD1.
1. PLoS Biol. - published July 23, 2014
2. Huang H, Levin EJ, Liu S, Bai Y, Lockless SW, Zhou M
Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system.
1. Elife - published July 23, 2014
2. Wang W, Whorton MR, MacKinnon R
FGF5 is a crucial regulator of hair length in humans.
1. Proc. Natl. Acad. Sci. U.S.A. - published July 22, 2014
2. Higgins CA, Petukhova L, Harel S, Ho YY, Drill E, Shapiro L, Wajid M, Christiano AM
Retromer binding to FAM21 and the WASH complex is perturbed by the Parkinson disease-linked VPS35(D620N) mutation.
1. Curr. Biol. - published July 21, 2014
2. McGough IJ, Steinberg F, Jia D, Barbuti PA, McMillan KJ, Heesom KJ, Whone AL, Caldwell MA, Billadeau DD, Rosen MK, Cullen PJ
Drosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase β and regulates complex V activity.
1. J. Cell Biol. - published July 21, 2014
2. Rahman M, Nirala NK, Singh A, Zhu LJ, Taguchi K, Bamba T, Fukusaki E, Shaw LM, Lambright DG, Acharya JK, Acharya UR
Structure and Stereochemical Determination of Hypogeamicins from a Cave-Derived Actinomycete.
1. J. Nat. Prod. - published July 21, 2014
2. Derewacz DK, McNees CR, Scalmani G, Covington CL, Shanmugam G, Marnett LJ, Polavarapu PL, Bachmann BO
Long-term disease-free survival achieved by anti-angiogenic therapy plus surgery in a hepatocellular carcinoma patient with extensive liver involvement and lung metastases.
1. J. Formos. Med. Assoc. - published July 20, 2014
2. Shao YY, Ho MC, Cheng AL, Hsu CH
The oligomeric states of the purified sigma-1 receptor are stabilized by ligands.
1. J. Biol. Chem. - published July 18, 2014
2. Gromek KA, Suchy FP, Meddaugh HR, Wrobel RL, LaPointe LM, Chu UB, Primm JG, Ruoho AE, Senes A, Fox BG
Endocytotic routes of cobra cardiotoxins depend on spatial distribution of positively charged and hydrophobic domains to target distinct types of sulfated glycoconjugates on cell surface.
1. J. Biol. Chem. - published July 18, 2014
2. Lee SC, Lin CC, Wang CH, Wu PL, Huang HW, Chang CI, Wu WG
Engineered proteins with desired specificity: DARPins, other alternative scaffolds and bispecific IgGs.
1. Curr. Opin. Struct. Biol. - published July 18, 2014
2. Jost C, Plückthun A
The structural basis of transfer RNA mimicry and conformational plasticity by a viral RNA.
1. Nature - published July 17, 2014
2. Colussi TM, Costantino DA, Hammond JA, Ruehle GM, Nix JC, Kieft JS
A novel class of succinimide-derived negative allosteric modulators of metabotropic glutamate receptor subtype 1 provides insight into a disconnect in activity between the rat and human receptors.
1. ACS Chem Neurosci - published July 16, 2014
2. Cho HP, Engers DW, Venable DF, Niswender CM, Lindsley CW, Conn PJ, Emmitte KA, Rodriguez AL
Crystal structure reveals conservation of amyloid-β conformation recognized by 3D6 following humanization to bapineuzumab.
1. Alzheimers Res Ther - published July 16, 2014
2. Feinberg H, Saldanha JW, Diep L, Goel A, Widom A, Veldman GM, Weis WI, Schenk D, Basi GS
Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.
1. Nat. Struct. Mol. Biol. - published July 16, 2014
2. Schlundt A, Heinz GA, Janowski R, Geerlof A, Stehle R, Heissmeyer V, Niessing D, Sattler M
Early detection of liver fibrosis in rats using 3-D ultrasound Nakagami imaging: a feasibility evaluation.
1. Ultrasound Med Biol - published July 16, 2014
2. Ho MC, Tsui PH, Lee YH, Chen YS, Chen CN, Lin JJ, Chang CC
Altered (transition) states: mechanisms of solution and enzyme catalyzed RNA 2'-O-transphosphorylation.
1. Curr Opin Chem Biol - published July 16, 2014
2. Kellerman DL, York DM, Piccirilli JA, Harris ME
Proteins feel more than they see: fine-tuning of binding affinity by properties of the non-interacting surface.
1. J. Mol. Biol. - published July 15, 2014
2. Kastritis PL, Rodrigues JP, Folkers GE, Boelens R, Bonvin AM
Structural and functional characterization of the α-tubulin acetyltransferase MEC-17.
1. J. Mol. Biol. - published July 15, 2014
2. Davenport AM, Collins LN, Chiu H, Minor PJ, Sternberg PW, Hoelz A
Synthesis and biological evaluation of substituted 3-anilino-quinolin-2(1H)-ones as PDK1 inhibitors.
1. Bioorg. Med. Chem. - published July 15, 2014
2. O'Brien NJ, Brzozowski M, Wilson DJ, Deady LW, Abbott BM
Roux-en-Y gastric bypass does not affect daily water intake or the drinking response to dipsogenic stimuli in rats.
1. Am. J. Physiol. Regul. Integr. Comp. Physiol. - published July 15, 2014
2. Marshall A, Santollo J, Corteville C, Lutz TA, Daniels D
Modest effects of lipid modifications on the structure of caveolin-3.
1. Biochemistry - published July 15, 2014
2. Kim JH, Peng D, Schlebach JP, Hadziselimovic A, Sanders CR
Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains.
1. Proc. Natl. Acad. Sci. U.S.A. - published July 15, 2014
2. Fera D, Schmidt AG, Haynes BF, Gao F, Liao HX, Kepler TB, Harrison SC
Structures of benzylsuccinate synthase elucidate roles of accessory subunits in glycyl radical enzyme activation and activity.
1. Proc. Natl. Acad. Sci. U.S.A. - published July 15, 2014
2. Funk MA, Judd ET, Marsh EN, Elliott SJ, Drennan CL
Structural basis for the recruitment of glycogen synthase by glycogenin.
1. Proc. Natl. Acad. Sci. U.S.A. - published July 15, 2014
2. Zeqiraj E, Tang X, Hunter RW, García-Rocha M, Judd A, Deak M, von Wilamowitz-Moellendorff A, Kurinov I, Guinovart JJ, Tyers M, Sakamoto K, Sicheri F
A new broadband homonuclear mixing pulse for NMR with low applied power.
1. J Chem Phys - published July 14, 2014
2. Coote P, Leigh KE, Yu TY, Khaneja N, Wagner G, Arthanari H
Usefulness of Lung Ultrasound in the Diagnosis of Community-acquired Pneumonia in Children.
1. Pediatr Neonatol - published July 14, 2014
2. Ho MC, Ker CR, Hsu JH, Wu JR, Dai ZK, Chen IC
Comparative genome sequencing reveals chemotype-specific gene clusters in the toxigenic black mold Stachybotrys.
1. BMC Genomics - published July 13, 2014
2. Semeiks J, Borek D, Otwinowski Z, Grishin NV
A structural model of the active ribosome-bound membrane protein insertase YidC.
1. Elife - published July 12, 2014
2. Wickles S, Singharoy A, Andreani J, Seemayer S, Bischoff L, Berninghausen O, Soeding J, Schulten K, van der Sluis EO, Beckmann R
Two amino acid residues confer different binding affinities of Abelson family kinase SRC homology 2 domains for phosphorylated cortactin.
1. J. Biol. Chem. - published July 11, 2014
2. Gifford SM, Liu W, Mader CC, Halo TL, Machida K, Boggon TJ, Koleske AJ
Recent progress on the structure and function of the TrkH/KtrB ion channel.
1. Curr. Opin. Struct. Biol. - published July 11, 2014
2. Levin EJ, Zhou M
Bacterial cell wall. MurJ is the flippase of lipid-linked precursors for peptidoglycan biogenesis.
1. Science - published July 11, 2014
2. Sham LT, Butler EK, Lebar MD, Kahne D, Bernhardt TG, Ruiz N
Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitment.
1. FASEB J. - published July 11, 2014
2. Rajasekaran D, Zierow S, Syed M, Bucala R, Bhandari V, Lolis EJ
Tetrahydronaphthyridine and dihydronaphthyridinone ethers as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu₅).
1. J. Med. Chem. - published July 10, 2014
2. Turlington M, Malosh C, Jacobs J, Manka JT, Noetzel MJ, Vinson PN, Jadhav S, Herman EJ, Lavreysen H, Mackie C, Bartolomé-Nebreda JM, Conde-Ceide S, Martín-Martín ML, Tong HM, López S, MacDonald GJ, Steckler T, Daniels JS, Weaver CD, Niswender CM, Jones CK, Conn PJ, Lindsley CW, Stauffer SR
Exploiting subtle structural differences in heavy-atom derivatives for experimental phasing.
1. Acta Crystallogr. D Biol. Crystallogr. - published July 10, 2014
2. Wang J, Li Y, Modis Y
Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs).
1. Chem. Rev. - published July 9, 2014
2. Theillet FX, Binolfi A, Frembgen-Kesner T, Hingorani K, Sarkar M, Kyne C, Li C, Crowley PB, Gierasch L, Pielak GJ, Elcock AH, Gershenson A, Selenko P
Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation.
1. Transl Psychiatry - published July 9, 2014
2. Bluett RJ, Gamble-George JC, Hermanson DJ, Hartley ND, Marnett LJ, Patel S
Bacterial sigma factors: a historical, structural, and genomic perspective.
1. Annu. Rev. Microbiol. - published July 9, 2014
2. Feklístov A, Sharon BD, Darst SA, Gross CA
Spontaneous self-assembly of engineered armadillo repeat protein fragments into a folded structure.
1. Structure - published July 8, 2014
2. Watson RP, Christen MT, Ewald C, Bumbak F, Reichen C, Mihajlovic M, Schmidt E, Güntert P, Caflisch A, Plückthun A, Zerbe O
Structural studies of the spinosyn forosaminyltransferase, SpnP.
1. Biochemistry - published July 8, 2014
2. Isiorho EA, Jeon BS, Kim NH, Liu HW, Keatinge-Clay AT
The LxVP and PxIxIT NFAT motifs bind jointly to overlapping epitopes on calcineurin's catalytic domain distant to the regulatory domain.
1. Structure - published July 8, 2014
2. Gal M, Li S, Luna RE, Takeuchi K, Wagner G
Macrolide antibiotics allosterically predispose the ribosome for translation arrest.
1. Proc. Natl. Acad. Sci. U.S.A. - published July 8, 2014
2. Sothiselvam S, Liu B, Han W, Ramu H, Klepacki D, Atkinson GC, Brauer A, Remm M, Tenson T, Schulten K, Vázquez-Laslop N, Mankin AS
FOXO1-mediated activation of Akt plays a critical role in vascular homeostasis.
1. Circ. Res. - published July 7, 2014
2. Dharaneeswaran H, Abid MR, Yuan L, Dupuis D, Beeler D, Spokes KC, Janes L, Sciuto T, Kang PM, Jaminet SC, Dvorak A, Grant MA, Regan ER, Aird WC
Structural basis for ligand exchange on Au(25)(SR)(18).
1. Inorg Chem - published July 7, 2014
2. Ni TW, Tofanelli MA, Phillips BD, Ackerson CJ
Constitutively oxidized CXXC motifs within the CD3 heterodimeric ectodomains of the T cell receptor complex enforce the conformation of juxtaposed segments.
1. J. Biol. Chem. - published July 4, 2014
2. Brazin KN, Mallis RJ, Li C, Keskin DB, Arthanari H, Gao Y, Wu SL, Karger BL, Wagner G, Reinherz EL
Proposed carrier lipid-binding site of undecaprenyl pyrophosphate phosphatase from Escherichia coli.
1. J. Biol. Chem. - published July 4, 2014
2. Chang HY, Chou CC, Hsu MF, Wang AH
Transplanting supersites of HIV-1 vulnerability.
1. PLoS One - published July 4, 2014
2. Zhou T, Zhu J, Yang Y, Gorman J, Ofek G, Srivatsan S, Druz A, Lees CR, Lu G, Soto C, Stuckey J, Burton DR, Koff WC, Connors M, Kwong PD
A spatial simulation approach to account for protein structure when identifying non-random somatic mutations.
1. BMC Bioinformatics - published July 4, 2014
2. Ryslik GA, Cheng Y, Cheung KH, Bjornson RD, Zelterman D, Modis Y, Zhao H
Contribution of glutamine residues in the helix 4-5 loop to capsid-capsid interactions in simian immunodeficiency virus of macaques.
1. J. Virol. - published July 4, 2014
2. Tipper C, Sodroski JG
Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis.
1. Science - published July 4, 2014
2. Lu M, Lawrence DA, Marsters S, Acosta-Alvear D, Kimmig P, Mendez AS, Paton AW, Paton JC, Walter P, Ashkenazi A
Direct evaluation of tRNA aminoacylation status by the T-box riboswitch using tRNA-mRNA stacking and steric readout.
1. Mol Cell - published July 3, 2014
2. Zhang J, Ferré-D'Amaré AR
The histone variant H2A.W defines heterochromatin and promotes chromatin condensation in Arabidopsis.
1. Cell - published July 3, 2014
2. Yelagandula R, Stroud H, Holec S, Zhou K, Feng S, Zhong X, Muthurajan UM, Nie X, Kawashima T, Groth M, Luger K, Jacobsen SE, Berger F
Structural basis of nSH2 regulation and lipid binding in PI3Kα.
1. Oncotarget - published July 3, 2014
2. Miller MS, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB
Frizzled3 is required for the development of multiple axon tracts in the mouse central nervous system.
1. Proc Natl Acad Sci U S A - published July 2, 2014
2. Hua ZL, Jeon S, Caterina MJ, Nathans J
Broad-spectrum allosteric inhibition of herpesvirus proteases.
1. Biochemistry - published July 2, 2014
2. Gable JE, Lee GM, Jaishankar P, Hearn BR, Waddling CA, Renslo AR, Craik CS
An unstable Th epitope of P. falciparum fosters central memory T cells and anti-CS antibody responses.
1. PLoS ONE - published July 2, 2014
2. Parra-López CA, Bernal-Estévez D, Vargas LE, Pulido-Calixto C, Salazar LM, Calvo-Calle JM, Stern LJ
Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites.
1. PLoS Biol. - published July 2, 2014
2. Sleebs BE, Lopaticki S, Marapana DS, O'Neill MT, Rajasekaran P, Gazdik M, Günther S, Whitehead LW, Lowes KN, Barfod L, Hviid L, Shaw PJ, Hodder AN, Smith BJ, Cowman AF, Boddey JA
Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor.
1. Sci Transl Med - published July 2, 2014
2. Pegu A, Yang ZY, Boyington JC, Wu L, Ko SY, Schmidt SD, McKee K, Kong WP, Shi W, Chen X, Todd JP, Letvin NL, Huang J, Nason MC, Hoxie JA, Kwong PD, Connors M, Rao SS, Mascola JR, Nabel GJ
Structure of a new DNA-binding domain which regulates pathogenesis in a wide variety of fungi.
1. Proc Natl Acad Sci U S A - published July 2, 2014
2. Lohse MB, Rosenberg OS, Cox JS, Stroud RM, Finer-Moore JS, Johnson AD
Growth of Diffraction-Quality Protein Crystals Using a Harvestable Microfluidic Device.
1. Cryst Growth Des - published July 2, 2014
2. Lee MJ, Faucher F, Jia Z
Retromer Binding to FAM21 and the WASH Complex Is Perturbed by the Parkinson Disease-Linked VPS35(D620N) Mutation.
1. Curr Biol - published July 2, 2014
2. McGough IJ, Steinberg F, Jia D, Barbuti PA, McMillan KJ, Heesom KJ, Whone AL, Caldwell MA, Billadeau DD, Rosen MK, Cullen PJ
Photoaffinity labeling of nicotinic receptors: diversity of drug binding sites!
1. J Mol Neurosci - published July 1, 2014
2. Hamouda AK, Jayakar SS, Chiara DC, Cohen JB
Structure-guided analysis of catalytic specificity of the abundantly secreted chitosanase SACTE_5457 from Streptomyces sp. SirexAA-E.
1. Proteins - published July 1, 2014
2. Takasuka TE, Bianchetti CM, Tobimatsu Y, Bergeman LF, Ralph J, Fox BG
Molecular basis of aflatoxin-induced mutagenesis-role of the aflatoxin B1-formamidopyrimidine adduct.
1. Carcinogenesis - published July 1, 2014
2. Lin YC, Li L, Makarova AV, Burgers PM, Stone MP, Lloyd RS
The neuroligins and their ligands: from structure to function at the synapse.
1. J Mol Neurosci - published July 1, 2014
2. Bourne Y, Marchot P
HIV-1 protease-substrate coevolution in nelfinavir resistance.
1. J Virol - published July 1, 2014
2. Kolli M, Ozen A, Kurt-Yilmaz N, Schiffer CA
Determinants of Moloney murine leukemia virus Gag-Pol and genomic RNA proportions.
1. J Virol - published July 1, 2014
2. Johnson SF, Collins JT, D'Souza VM, Telesnitsky A
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
1. Nat Biotechnol - published July 1, 2014
2. Wu X, Scott DA, Kriz AJ, Chiu AC, Hsu PD, Dadon DB, Cheng AW, Trevino AE, Konermann S, Chen S, Jaenisch R, Zhang F, Sharp PA
Structure of the LINGO-1-anti-LINGO-1 Li81 antibody complex provides insights into the biology of LINGO-1 and the mechanism of action of the antibody therapy.
1. J Pharmacol Exp Ther - published July 1, 2014
2. Pepinsky RB, Arndt JW, Quan C, Gao Y, Quintero-Monzon O, Lee X, Mi S
Proteolytic activation of the porcine epidemic diarrhea coronavirus spike fusion protein by trypsin in cell culture.
1. J Virol - published July 1, 2014
2. Wicht O, Li W, Willems L, Meuleman TJ, Wubbolts RW, van Kuppeveld FJ, Rottier PJ, Bosch BJ
Correlated cryogenic photoactivated localization microscopy and cryo-electron tomography.
1. Nat Methods - published July 1, 2014
2. Chang YW, Chen S, Tocheva EI, Treuner-Lange A, Löbach S, Søgaard-Andersen L, Jensen GJ
Structural and functional implications of the QUA2 domain on RNA recognition by GLD-1.
1. Nucleic Acids Res - published July 1, 2014
2. Daubner GM, Brümmer A, Tocchini C, Gerhardy S, Ciosk R, Zavolan M, Allain FH
Structural basis of the phosphorylation dependent complex formation of neurodegenerative disease protein Ataxin-1 and RBM17.
1. Biochem Biophys Res Commun - published July 1, 2014
2. Kim E, Lee Y, Choi S, Song JJ
Membrane association of the CD3ε signaling domain is required for optimal T cell development and function.
1. J. Immunol. - published July 1, 2014
2. Bettini ML, Guy C, Dash P, Vignali KM, Hamm DE, Dobbins J, Gagnon E, Thomas PG, Wucherpfennig KW, Vignali DA
LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures.
1. Nucleic Acids Res - published July 1, 2014
2. Duan Q, Flynn C, Niepel M, Hafner M, Muhlich JL, Fernandez NF, Rouillard AD, Tan CM, Chen EY, Golub TR, Sorger PK, Subramanian A, Ma'ayan A
LptE binds to and alters the physical state of LPS to catalyze its assembly at the cell surface.
1. Proc. Natl. Acad. Sci. U.S.A. - published July 1, 2014
2. Malojčić G, Andres D, Grabowicz M, George AH, Ruiz N, Silhavy TJ, Kahne D
Synchrotron-based small-angle X-ray scattering of proteins in solution.
1. Nat Protoc - published July 1, 2014
2. Skou S, Gillilan RE, Ando N
Targeted proteomics of myofilament phosphorylation and other protein posttranslational modifications.
1. Proteomics Clin Appl - published July 1, 2014
2. Ramirez-Correa GA, Martinez-Ferrando MI, Zhang P, Murphy AM
Dynamic effects of point source electroporation on the rat brain tissue.
1. Bioelectrochemistry - published July 1, 2014
2. Sharabi S, Last D, Guez D, Daniels D, Hjouj MI, Salomon S, Maor E, Mardor Y
Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice.
1. Proc Natl Acad Sci U S A - published July 1, 2014
2. Stöhr J, Condello C, Watts JC, Bloch L, Oehler A, Nick M, DeArmond SJ, Giles K, DeGrado WF, Prusiner SB
Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites.
1. Cell Rep - published July 1, 2014
2. Schwartz S, Mumbach MR, Jovanovic M, Wang T, Maciag K, Bushkin GG, Mertins P, Ter-Ovanesyan D, Habib N, Cacchiarelli D, Sanjana NE, Freinkman E, Pacold ME, Satija R, Mikkelsen TS, Hacohen N, Zhang F, Carr SA, Lander ES, Regev A
MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors.
1. Cancer Cell - published July 1, 2014
2. Wan L, Lu X, Yuan S, Wei Y, Guo F, Shen M, Yuan M, Chakrabarti R, Hua Y, Smith HA, Blanco MA, Chekmareva M, Wu H, Bronson RT, Haffty BG, Xing Y, Kang Y
Fulfilling the dream of a perfect genome editing tool.
1. Proc Natl Acad Sci U S A - published July 1, 2014
2. Spies M
Inventory of telomerase components in human cells reveals multiple subpopulations of hTR and hTERT.
1. Nucleic Acids Res - published July 1, 2014
2. Xi L, Cech TR
A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins.
1. Genes Dev - published July 1, 2014
2. Afroz T, Skrisovska L, Belloc E, Guillén-Boixet J, Méndez R, Allain FH
Crystallization and preliminary analysis of the NqrA and NqrC subunits of the Na+-translocating NADH:ubiquinone oxidoreductase from Vibrio cholerae.
1. Acta Crystallogr F Struct Biol Commun - published July 1, 2014
2. Vohl G, Nedielkov R, Claussen B, Casutt MS, Vorburger T, Diederichs K, Möller HM, Steuber J, Fritz G
A real-time all-atom structural search engine for proteins.
1. PLoS Comput Biol - published July 1, 2014
2. Gonzalez G, Hannigan B, DeGrado WF
Ambiguity of structure determination from a minimum of diffraction intensities.
1. Acta Crystallogr A Found Adv - published July 1, 2014
2. Al-Asadi A, Leggas D, Tsodikov OV