Member Publications

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71 Member Publications for December 2013

Radioligand Binding to Nanodisc-Reconstituted Membrane Transporters Assessed by the Scintillation Proximity Assay.
1. Biochemistry - published December 30, 2013
2. ML Nasr, SK Singh
Decision-tree based model analysis for efficient identification of parameter relations leading to different signaling states.
1. PLoS One - published December 25, 2013
2. Koch Y, Wolf T, Sorger PK, Eils R, Brors B
Backbone and side-chain NMR assignments for the C-terminal domain of mammalian Vps28.
1. Biomol NMR Assign - published December 24, 2013
2. TA Peterson, L Yu, RC Piper
Microbial and Animal Rhodopsins: Structures, Functions, and Molecular Mechanisms.
1. Chem Rev - published December 23, 2013
2. OP Ernst, DT Lodowski, M Elstner, P Hegemann, LS Brown, H Kandori
Base-displaced intercalation of the 2-amino-3-methylimidazo[4,5-f]quinolone N2-dG adduct in the NarI DNA recognition sequence.
1. Nucleic Acids Res - published December 23, 2013
2. KM Stavros, EK Hawkins, CJ Rizzo, MP Stone
Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism.
1. Nat Chem Biol - published December 22, 2013
2. DP Dowling, NA Bruender, AP Young, RM McCarty, V Bandarian, CL Drennan
Architecture of the large subunit of the mammalian mitochondrial ribosome.
1. Nature - published December 22, 2013
2. BJ Greber, D Boehringer, A Leitner, P Bieri, F Voigts-Hoffmann, JP Erzberger, M Leibundgut, R Aebersold, N Ban
High-pressure freezing: current state and future prospects.
1. Methods Mol Biol - published December 21, 2013
2. Kaech A, Ziegler U
The Interaction between Eukaryotic Initiation Factor 1A and eIF5 Retains eIF1 within Scanning Preinitiation Complexes.
1. Biochemistry - published December 19, 2013
2. RE Luna, H Arthanari, H Hiraishi, B Akabayov, L Tang, C Cox, MA Markus, LE Luna, Y Ikeda, R Watanabe, E Bedoya, C Yu, S Alikhan, G Wagner, K Asano
D14-SCFD3-dependent degradation of D53 regulates strigolactone signalling.
1. Nature - published December 19, 2013
2. F Zhou, Q Lin, L Zhu, Y Ren, K Zhou, N Shabek, F Wu, H Mao, W Dong, L Gan, W Ma, H Gao, J Chen, C Yang, D Wang, J Tan, X Zhang, X Guo, J Wang, L Jiang, X Liu, W Chen, J Chu, C Yan, K Ueno, S Ito, T Asami, Z Cheng, J Wang, C Lei, H Zhai, C Wu, H Wang, N Zheng, J Wan
LipL41, a hemin binding protein from Leptospira santarosai serovar Shermani.
1. PLoS One - published December 19, 2013
2. Lin MH, Chang YC, Hsiao CD, Huang SH, Wang MS, Ko YC, Yang CW, Sun YJ
Engineering protein thermostability using a generic activity-independent biophysical screen inside the cell.
1. Nat Commun - published December 19, 2013
2. I Asial, YX Cheng, H Engman, M Dollhopf, B Wu, P Nordlund, T Cornvik
STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry.
1. Nat Commun - published December 19, 2013
2. PB Stathopulos, R Schindl, M Fahrner, L Zheng, GM Gasmi-Seabrook, M Muik, C Romanin, M Ikura
Mantle Cell Lymphoma in Cyclin D1 Transgenic Mice with Bim-deficient B-cells.
1. Blood - published December 18, 2013
2. SG Katz, JL Labelle, H Meng, RP Valeriano, JK Fisher, H Sun, SJ Rodig, SH Kleinstein, LD Walensky
Structural insights into the globular tails of the human type v myosins Myo5a, Myo5b, And Myo5c.
1. PLoS One - published December 17, 2013
2. Velvarska H, Niessing D
Lipoprotein Activators Stimulate Escherichia coli Penicillin-Binding Proteins by Different Mechanisms.
1. J Am Chem Soc - published December 17, 2013
2. TJ Lupoli, MD Lebar, M Markovski, T Bernhardt, D Kahne, S Walker
Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design.
1. Protein Sci - published December 17, 2013
2. MF Mabanglo, MA Hast, NB Lubock, HW Hellinga, LS Beese
Analysis of riboswitch structure and ligand binding using small-angle X-ray scattering (SAXS).
1. Methods Mol Biol - published December 10, 2013
2. Baird NJ, Ferré-D'Amaré AR
The Molecular Chaperone Hsp70 Activates Protein Phosphatase 5 (PP5) By Binding the Tetratricopeptide Repeat (TPR) Domain.
1. J Biol Chem - published December 10, 2013
2. JN Connarn, VA Assimon, RA Reed, E Tse, DR Southworth, ER Zuiderweg, JE Gestwicki, D Sun
Role of Loc1p in assembly and reorganization of nuclear ASH1 messenger ribonucleoprotein particles in yeast.
1. Proc Natl Acad Sci U S A - published December 9, 2013
2. A Niedner, M Müller, BT Moorthy, RP Jansen, D Niessing
A phospho-BAD BH3 helix activates glucokinase by a mechanism distinct from that of allosteric activators.
1. Nat Struct Mol Biol - published December 8, 2013
2. NN Danial, LD Walensky, FM Matschinsky, MA Osundiji, GH Bird, E Patton, S Ljubicic, CR Braun, B Szlyk
Characterization of a Highly Flexible Self-Assembling Protein System Designed to Form Nano Cages.
1. Protein Sci - published December 8, 2013
2. EN Marsh, G Skiniotis, A Sciore, TM Franzmann, M Su, DP Patterson
Structural basis of the alternating-access mechanism in a bile acid transporter.
1. Nature - published December 8, 2013
2. JG McCoy, Y Pan, EJ Levin, X Zhou, R Sharma, B Kloss, R Bruni, M Quick, M Zhou
Botany. Shining light at microtubule crossroads.
1. Science - published December 6, 2013
2. A Roll-Mecak
HCF-1 is cleaved in the active site of O-GlcNAc transferase.
1. Science - published December 6, 2013
2. S Walker, W Herr, DJ Vocadlo, WF Zandberg, J Janetzko, T Bhuiyan, V Kapuria, J Jiang, MB Lazarus
Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36.
1. Nature - published December 5, 2013
2. Neculai D, Schwake M, Ravichandran M, Zunke F, Collins RF, Peters J, Neculai M, Plumb J, Loppnau P, Pizarro JC, Seitova A, Trimble WS, Saftig P, Grinstein S, Dhe-Paganon S
Structure of the TRPV1 ion channel determined by electron cryo-microscopy.
1. Nature - published December 5, 2013
2. Liao M, Cao E, Julius D, Cheng Y
TRPV1 structures in distinct conformations reveal activation mechanisms.
1. Nature - published December 5, 2013
2. Cao E, Liao M, Cheng Y, Julius D
Simultaneous prediction of binding free energy and specificity for PDZ domain-peptide interactions.
1. J Comput Aided Mol Des - published December 5, 2013
2. J Meiler, KW Kaufmann, G Lemmon, JJ Crivelli
Replication, Repair, and Translesion Polymerase Bypass of N(6)-Oxopropenyl-2'-deoxyadenosine.
1. Biochemistry - published December 3, 2013
2. LJ Marnett, FP Guengerich, CJ Rizzo, L Zhao, RL Eoff, SC Shuck, L Maddukuri
Interaction of the eukaryotic initiation factor 4E with 4E-BP2 at a dynamic bipartite interface.
1. Structure - published December 3, 2013
2. Lukhele S, Bah A, Lin H, Sonenberg N, Forman-Kay JD
Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of σ70 domain 1.1.
1. Proc Natl Acad Sci U S A - published December 3, 2013
2. SA Darst, S Wigneshweraraj, EA Campbell, D Brown, E Davis, B Bae
Discovery of chlamydial peptidoglycan reveals bacteria with murein sacculi but without FtsZ.
1. Nat Commun - published December 3, 2013
2. Pilhofer M, Aistleitner K, Biboy J, Gray J, Kuru E, Hall E, Brun YV, VanNieuwenhze MS, Vollmer W, Horn M, Jensen GJ
Refining a Jagged edge.
1. Structure - published December 3, 2013
2. Blacklow SC
Conformational dynamics of calcium-triggered activation of fusion by synaptotagmin.
1. Biophys J - published December 3, 2013
2. Krishnakumar SS, Kümmel D, Jones SJ, Radoff DT, Reinisch KM, Rothman JE
Flavin reduction activates Drosophila cryptochrome.
1. Proc Natl Acad Sci U S A - published December 2, 2013
2. BR Crane, MW Young, L Pollack, S Zhang, JM Tokuda, CC Manahan, D Top, AT Vaidya
BET-bromodomain inhibition of MYC-amplified Medulloblastoma.
1. Clin Cancer Res - published December 2, 2013
2. YJ Cho, R Beroukhim, JE Bradner, MW Kieran, FJ Swartling, WA Weiss, RJ Wechsler-Reya, KW Liu, J Qi, S Cheshier, SS Mitra, BR Paolella, WJ Gibson, N Vue, F Yu, S Masoud, R Zeid, SE Schumacher, S Bolin, Y Tang, S Gholamin, S Schubert, B Nguyen, G Bergthold, P Bandopadhayay, SH Cheshier, R Wechsler-Reya
Multiple mechanisms determine ER network morphology during the cell cycle in Xenopus egg extracts.
1. J Cell Biol - published December 2, 2013
2. TA Rapoport, TJ Mitchison, CM Field, FB Romano, S Wang
In vitro reconstitution of an mRNA-transport complex reveals mechanisms of assembly and motor activation.
1. J Cell Biol - published December 2, 2013
2. Heym RG, Zimmermann D, Edelmann FT, Israel L, Ökten Z, Kovar DR, Niessing D
Nucleotide and partner-protein control of bacterial replicative helicase structure and function.
1. Mol Cell - published December 2, 2013
2. Strycharska MS, Arias-Palomo E, Lyubimov AY, Erzberger JP, O'Shea VL, Bustamante CJ, Berger JM
The effect of novel rhenium compounds on lymphosarcoma, PC-3 prostate and myeloid leukemia cancer cell lines and an investigation on the DNA binding properties of one of these compounds through electronic spectroscopy.
1. J Bioprocess Biotech - published December 2, 2013
2. Parson C, Smith V, Krauss C, Banerjee HN, Reilly C, Krause JA, Wachira JM, Giri D, Winstead A, Mandal SK
Molecular origins of binding affinity: seeking the Archimedean point.
1. Curr Opin Struct Biol - published December 1, 2013
2. Kastritis PL, Bonvin AM
Defining the limits of homology modeling in information-driven protein docking.
1. Proteins - published December 1, 2013
2. Rodrigues JP, Melquiond AS, Karaca E, Trellet M, van Dijk M, van Zundert GC, Schmitz C, de Vries SJ, Bordogna A, Bonati L, Kastritis PL, Bonvin AM
Heterologous expression and purification of an active human TRPV3 ion channel.
1. FEBS J - published December 1, 2013
2. Kol S, Braun C, Thiel G, Doyle DA, Sundström M, Gourdon P, Nissen P
Mutational analysis of the stability of Psb27 from Synechocystis sp. PCC 6803: implications for models of Psb27 structure and binding to CP43.
1. Eur Biophys J - published December 1, 2013
2. Mabbitt PD, Eaton-Rye JJ, Wilbanks SM
CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis.
1. Free Radic Biol Med - published December 1, 2013
2. Abdelmegeed MA, Banerjee A, Jang S, Yoo SH, Yun JW, Gonzalez FJ, Keshavarzian A, Song BJ
αE-catenin actin-binding domain alters actin filament conformation and regulates binding of nucleation and disassembly factors.
1. Mol Biol Cell - published December 1, 2013
2. Hansen SD, Kwiatkowski AV, Ouyang CY, Liu H, Pokutta S, Watkins SC, Volkmann N, Hanein D, Weis WI, Mullins RD, Nelson WJ
Supervillin binding to myosin II and synergism with anillin are required for cytokinesis.
1. Mol Biol Cell - published December 1, 2013
2. Smith TC, Fridy PC, Li Y, Basil S, Arjun S, Friesen RM, Leszyk J, Chait BT, Rout MP, Luna EJ
An in vitro evolved glmS ribozyme has the wild-type fold but loses coenzyme dependence.
1. Nat Chem Biol - published December 1, 2013
2. Lau MW, Ferré-D'Amaré AR
Effect of multimerization on membrane association of Rous sarcoma virus and HIV-1 matrix domain proteins.
1. J Virol - published December 1, 2013
2. Dick RA, Kamynina E, Vogt VM
Selectivity of Ni(II) and Zn(II) binding to Sporosarcina pasteurii UreE, a metallochaperone in the urease assembly: a calorimetric and crystallographic study.
1. J Biol Inorg Chem - published December 1, 2013
2. Zambelli B, Banaszak K, Merloni A, Kiliszek A, Rypniewski W, Ciurli S
The nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome.
1. Mol Biol Cell - published December 1, 2013
2. Niepel M, Molloy KR, Williams R, Farr JC, Meinema AC, Vecchietti N, Cristea IM, Chait BT, Rout MP, Strambio-De-Castillia C
Identification of anaplastic lymphoma kinase as a potential therapeutic target in Basal Cell Carcinoma.
1. Oncotarget - published December 1, 2013
2. Ning H, Mitsui H, Wang CQ, Suárez-Fariñas M, Gonzalez J, Shah KR, Chen J, Coats I, Felsen D, Carucci JA, Krueger JG
MoeH5: a natural glycorandomizer from the moenomycin biosynthetic pathway.
1. Mol Microbiol - published December 1, 2013
2. Ostash B, Campbell J, Luzhetskyy A, Walker S
Histone H4 promotes prothrombin autoactivation.
1. J Biol Chem - published December 1, 2013
2. Barranco-Medina S, Pozzi N, Vogt AD, Di Cera E
The structural basis of FtsY recruitment and GTPase activation by SRP RNA.
1. Mol Cell - published December 1, 2013
2. Voigts-Hoffmann F, Schmitz N, Shen K, Shan SO, Ataide SF, Ban N
Crystal structure of Vδ1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human γδ T cells.
1. Immunity - published December 1, 2013
2. Luoma AM, Castro CD, Mayassi T, Bembinster LA, Bai L, Picard D, Anderson B, Scharf L, Kung JE, Sibener LV, Savage PB, Jabri B, Bendelac A, Adams EJ
Molecular basis of UG-rich RNA recognition by the human splicing factor TDP-43.
1. Nat Struct Mol Biol - published December 1, 2013
2. Lukavsky PJ, Daujotyte D, Tollervey JR, Ule J, Stuani C, Buratti E, Baralle FE, Damberger FF, Allain FH
The Cmr complex: an RNA-guided endoribonuclease.
1. Biochem Soc Trans - published December 1, 2013
2. Bailey S
CBC-ARS2 stimulates 3'-end maturation of multiple RNA families and favors cap-proximal processing.
1. Nat Struct Mol Biol - published December 1, 2013
2. Hallais M, Pontvianne F, Andersen PR, Clerici M, Lener D, Benbahouche Nel H, Gostan T, Vandermoere F, Robert MC, Cusack S, Verheggen C, Jensen TH, Bertrand E
Structural insights into DNA replication without hydrogen bonds.
1. J Am Chem Soc - published December 1, 2013
2. Betz K, Malyshev DA, Lavergne T, Welte W, Diederichs K, Romesberg FE, Marx A
Energetic analysis of the rhodopsin-G-protein complex links the α5 helix to GDP release.
1. Nat Struct Mol Biol - published December 1, 2013
2. J Meiler, HE Hamm, RA Stein, AI Kaya, AM Preininger, NS Alexander
Molecular basis of usher pore gating in Escherichia coli pilus biogenesis.
1. Proc Natl Acad Sci U S A - published December 1, 2013
2. Volkan E, Kalas V, Pinkner JS, Dodson KW, Henderson NS, Pham T, Waksman G, Delcour AH, Thanassi DG, Hultgren SJ
Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1.
1. Proc Natl Acad Sci U S A - published December 1, 2013
2. Li SH, Reinke AA, Sanders KL, Emal CD, Whisstock JC, Stuckey JA, Lawrence DA
Structural mechanism of ligand activation in human GABA(B) receptor.
1. Nature - published December 1, 2013
2. Geng Y, Bush M, Mosyak L, Wang F, Fan QR
Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain.
1. Acta Crystallogr D Biol Crystallogr - published December 1, 2013
2. Mortenson DE, Kreitler DF, Yun HG, Gellman SH, Forest KT
Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12.
1. Cell Rep - published December 1, 2013
2. Wu Y, West AP Jr, Kim HJ, Thornton ME, Ward AB, Bjorkman PJ
Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons.
1. Elife - published December 1, 2013
2. Hua ZL, Smallwood PM, Nathans J
Heat shock transcription factor σ32 co-opts the signal recognition particle to regulate protein homeostasis in E. coli.
1. PLoS Biol - published December 1, 2013
2. Lim B, Miyazaki R, Neher S, Siegele DA, Ito K, Walter P, Akiyama Y, Yura T, Gross CA
Improving the Resistance Profile of Hepatitis C NS3/4A Inhibitors: Dynamic Substrate Envelope Guided Design.
1. J Chem Theory Comput - published December 1, 2013
2. Ozen A, Sherman W, Schiffer CA
Design, Synthesis, and Antiviral Evaluation of Chimeric Inhibitors of HIV Reverse Transcriptase.
1. ACS Med Chem Lett - published December 1, 2013
2. Iyidogan P, Sullivan TJ, Chordia MD, Frey KM, Anderson KS