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  • The SBGrid Consortium provides structural biologists worldwide with access to the software they need to discover the shapes of the molecules of life. Read more in eLIFE and Acta Cryst.

  • The Project MAC display system, circa 1965. Read more about the history of molecular graphics software and UCSF Chimera in our SBGrid Tale featuring Bob Langridge and Tom Ferrin.

  • Train the Trainer Workshops: continuing education for structural biology mentors on cryoEM data processing workflows; resources PIs can take back to the laboratory. Funded by NIH R25 GM151273.

  • Personal Installation Manager: a structural biology app store; users install preferred applications/ versions on laptops or personal workstations, with graphical or CLI interfaces for Mac or Linux. More details.

  • SBCloud: AWS platform optimized for structural biology; pre-configured with scientific software for cryoEM & other techniques; user-friendly Open OnDemand interface; seamless Slurm job submission.

  • Capsules isolate the software runtime environment, encapsulating executables, libraries, and version-specific dependencies to provide conflict-free, zero-configuration access to structural biology software. Learn more.

SBGrid Consortium homepage

Recent Software Updates

Software updates
Feb 18 | Cryosamba

Cryosamba is a deep learning based tool for denoising cryo-ET datasets. It is designed to accept .mrc, .rc and .tif single 3D files, or ca… >>

Feb 18 | Gapstop(TM)

is GPU-Accelerated Python STOPgap for Template Matching for fast template matching (TM) in cryo electron tomograms that is based on TM rou… >>

Feb 18 | AlphaFold

an implementation of the inference pipeline of AlphaFold v2.0 using a completely new model that was entered in CASP14. >>

Feb 14 | USF Gerard Utilities

a Swiss Army knife of crystallography tools. The installation includes the packages from RAVE, SBIN, X-UTIL, VOIDOO, DEJAVU and SPASM. … >>

Feb 11 | Vesicle-Picker

a tool that identifies membrane proteins in cryo-EM micrographs by using the Segment Anything Model and integrating with cryoSPARC. >>

Feb 11 | DeepDeWedge

the implementation of a deep learning method for simultaneous denoising and missing wedge reconstruction in cryogenic electron tomography >>

Feb 10 | IMOD

a set of image processing, modeling and display programs used for tomographic reconstruction and for 3D reconstruction of EM serial section… >>

Feb 07 | pdb_extract

a program suite that contains tools and examples for extracting data from many structure determination applications and assembles the data … >>

Feb 04 | LucaProt

A novel deep learning framework that incorporates protein amino acid sequence and structural information to predict protein function. >>

Feb 16 | R

a free software environment for statistical computing and graphics. >>

Thanks to the National Science Foundation

With partial support from the NIH R25 Continuing Education for Structural Biology Mentors #GM151273, in collaboration with Co-PI Jamaine Davis; the NSF Research Coordination Network MCB #0639193, and NSF EAGER #1448069. Please cite SBGrid's eLife paper and follow our publication guidelines.

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Latest upgrades from SBGrid, including latest software updates, new members and special events. Published montly by SBGrid.

SBGrid Webinar Series

Join us for our Software Webinar Series - Tuesdays at 12pm ET - to hear from software developers about what's new in structural biology. Community members connect via Zoom. Subscribe …

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Capsules Technology

We have recently published a manuscript describing our Capsules technology used to deploy SBGrid and BioGrids software collections. Read more in Acta Cryst Section D, special 75th ICUR anniversary issue, …

Death Metal

Death Metal

For many people, the phrase “nutritional immunity” may evoke special foods or vitamin supplements believed to boost immunity, such as chicken soup, vitamin C, or tea with honey. But for …

Context Matters

Context Matters

Bing Chen has spent his structural biology career seeking a better look at how HIV particles enter host cells to make people sick. In fact, his research group at Boston …

Member publications

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