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  • The SBGrid Consortium provides structural biologists worldwide with access to the software they need to discover the shapes of the molecules of life. Read more in eLIFE and Acta Cryst.

  • The Project MAC display system, circa 1965. Read more about the history of molecular graphics software and UCSF Chimera in our SBGrid Tale featuring Bob Langridge and Tom Ferrin.

  • Train the Trainer Workshops: continuing education for structural biology mentors on cryoEM data processing workflows; resources PIs can take back to the laboratory. Funded by NIH R25 GM151273.

  • Personal Installation Manager: a structural biology app store; users install preferred applications/ versions on laptops or personal workstations, with graphical or CLI interfaces for Mac or Linux. More details.

  • SBCloud: AWS platform optimized for structural biology; pre-configured with scientific software for cryoEM & other techniques; user-friendly Open OnDemand interface; seamless Slurm job submission.

  • Capsules isolate the software runtime environment, encapsulating executables, libraries, and version-specific dependencies to provide conflict-free, zero-configuration access to structural biology software. Learn more.

SBGrid Consortium homepage

Recent Software Updates

Software updates
Apr 01 | MAVEn

is a tool for the systematic analysis of compositionally-heterogeneous cryo-EM datasets. MAVEn is designed to work downstream of cryoDRGN, … >>

Apr 01 | VISDEM

is a cryo‑EM density map sharpening tool that estimates the underlying atomic distribution of a protein from the density map and computes t… >>

Apr 01 | PEET

(Particle Estimation for Electron Tomography) a package for aligning and averaging particles in 3-D subvolumes extracted from tomograms. I… >>

Apr 01 | RELION composite masks

a RELION 4 tool with support for composite masks >>

Mar 31 | XDS

(X-ray Detector Software) a software tool for processing single-crystal monochromatic diffraction data recorded by the rotation method. >>

Mar 31 | OpenMPI

an open source Message Passing Interface implementation that is developed and maintained by a consortium of academic, research, and industr… >>

Mar 28 | CNS

(Crystallography & NMR System) an X-ray crystallography suite used for refinement, phasing, and molecular replacement. >>

Mar 26 | Protenix

a trainable PyTorch reproduction of AlphaFold 3. >>

Mar 25 | smap

a tool for detecting unlabeled macromolecules in 2D Cryo-EM images of cells that uses high-resolution template matching. >>

Mar 20 | ChimeraX

a tool of the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), fo… >>

Thanks to the National Science Foundation

With partial support from the NIH R25 Continuing Education for Structural Biology Mentors #GM151273, in collaboration with Co-PI Jamaine Davis; the NSF Research Coordination Network MCB #0639193, and NSF EAGER #1448069. Please cite SBGrid's eLife paper and follow our publication guidelines.

Latest news

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Latest upgrades from SBGrid, including latest software updates, new members and special events. Published montly by SBGrid.

SBGrid Webinar Series

Join us for our Software Webinar Series - Tuesdays at 12pm ET - to hear from software developers about what's new in structural biology. Community members connect via Zoom. Subscribe …

SBGrid/Harvard Shield

Capsules Technology

We have recently published a manuscript describing our Capsules technology used to deploy SBGrid and BioGrids software collections. Read more in Acta Cryst Section D, special 75th ICUR anniversary issue, …

Death Metal

Death Metal

For many people, the phrase “nutritional immunity” may evoke special foods or vitamin supplements believed to boost immunity, such as chicken soup, vitamin C, or tea with honey. But for …

Context Matters

Context Matters

Bing Chen has spent his structural biology career seeking a better look at how HIV particles enter host cells to make people sick. In fact, his research group at Boston …

Member publications

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