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  • The SBGrid Consortium provides structural biologists worldwide with access to the software they need to discover the shapes of the molecules of life. Read more in eLIFE and Acta Cryst.

  • The Project MAC display system, circa 1965. Read more about the history of molecular graphics software and UCSF Chimera in our SBGrid Tale featuring Bob Langridge and Tom Ferrin.

  • Train the Trainer Workshops: continuing education for structural biology mentors on cryoEM data processing workflows; resources PIs can take back to the laboratory. Funded by NIH R25 GM151273.

  • Personal Installation Manager: a structural biology app store; users install preferred applications/ versions on laptops or personal workstations, with graphical or CLI interfaces for Mac or Linux.

  • SBCloud: AWS platform optimized for structural biology; pre-configured with scientific software for cryoEM & other techniques; user-friendly Open OnDemand interface; seamless Slurm job submission.

  • Capsules isolate the software runtime environment, encapsulating executables, libraries, and version-specific dependencies to provide conflict-free, zero-configuration access to structural biology software. Learn more.

SBGrid Consortium homepage

Recent Software Updates

Software updates
Nov 05 | MiLoPYP

MiLoPYP: self-supervised molecular pattern mining and particle localization in situ >>

Oct 30 | AreTomo3

a multi-GPU accelerated software package that enables real-time fully automated reconstruction of cryoET tomograms in parallel with cryoET … >>

Oct 30 | DeepFRI

Deep functional residue identification >>

Oct 30 | Starparser

a package implemented in Python to manipulate Relion star files including counting, modifying, plotting, and sifting the data. >>

Oct 16 | cryosparc-tools

a toolkit for interfacing with CryoSPARC. >>

Oct 15 | MemBrain-Seg

a tool for membrane segmentation in 3D for cryo-electron tomography (cryo-ET). >>

Oct 11 | DRGN-AI

a neural network-based algorithm for ab initio heterogeneous cryo-EM reconstruction. >>

Oct 10 | Warp

a set of tools for cryo-EM and cryo-ET data processing including, among other tools: Warp, M, WarpTools, MTools, MCore, and Noise2Map. >>

Oct 28 | CryoSegNet

a tool for accurate cryo-EM protein particle picking by integrating the foundational AI image segmentation model and specialized U-Net >>

Oct 09 | ShelXle

a cute graphical user interface for SHELXL. >>

Thanks to the National Science Foundation

With partial support from the NIH R25 Continuing Education for Structural Biology Mentors #GM151273, in collaboration with Co-PI Jamaine Davis; the NSF Research Coordination Network MCB #0639193, and NSF EAGER #1448069. Please cite SBGrid's eLife paper and follow our publication guidelines.

Latest news

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Read our September newsletter

Latest upgrades from SBGrid, including latest software updates, new members and special events. Published montly by SBGrid.

SBGrid Webinar Series

Join us for our Software Webinar Series - Tuesdays at 12pm ET - to hear from software developers about what's new in structural biology. Community members connect via Zoom. Subscribe …

SBGrid/Harvard Shield

Capsules Technology

We have recently published a manuscript describing our Capsules technology used to deploy SBGrid and BioGrids software collections. Read more in Acta Cryst Section D, special 75th ICUR anniversary issue, …

Death Metal

Death Metal

For many people, the phrase “nutritional immunity” may evoke special foods or vitamin supplements believed to boost immunity, such as chicken soup, vitamin C, or tea with honey. But for …

Context Matters

Context Matters

Bing Chen has spent his structural biology career seeking a better look at how HIV particles enter host cells to make people sick. In fact, his research group at Boston …

Member publications

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