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45 Member Publications for May 2026

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CRISPR base editor screening identifies spectrum of MEN1 mutations impacting menin inhibitors in clinical trials.
1. Nat Commun - published May 9, 2026
2. Bourgeois W, Rice HE, Wenge DV, Perner F, Yue H, Regalado BD, Wan G, Schroeder JC, Sommerschield A, Hatton C, Singh S, Singh S, Bijpuria S, McKeever BM, Miller WH, Safer JF, Iqbal S, Perry JA, Fischer ES, Doench JG, McGeehan GM, Cutler JA, Armstrong SA
Tunable TriPcides suppress virulence factor secretion during Staphylococcus aureus infection and kill dormant cells.
1. Sci Adv - published May 8, 2026
2. Tükenmez H, Nye TM, Singh P, Mychack A, Bonde M, Hickerson S, Obernuefemann CLP, Pinkner JS, Zhu S, Sarkar S, Bharate JB, van der Lingen I, Ntuyenm AQ, Rao VUB, Lindgren AEG, Klein H, Zou Z, Dodson KW, Walker S, Mateus A, Johansson J, Caparon MG, Almqvist F, Hultgren SJ
DNA binding and lesion recognition by the bacterial interstrand DNA crosslink glycosylase AlkX.
1. EMBO Rep - published May 8, 2026
2. Cai Y, Kunkle DE, Edinbugh MD, Bradley NP, Skaar EP, Eichman BF
PI3K Regulates Wild-type RAS Signaling to Confer Resistance to KRAS Inhibition.
1. Cancer Res - published May 7, 2026
2. Ge X, Singh J, Li W, Markham CS, Ruiz CF, Stites EC, Bhattacharyya M, Liu Y, Muzumdar MD
Cellular and molecular basis of PfCoronin function in artemisinin resistance in Plasmodium falciparum.
1. Nat Commun - published May 7, 2026
2. Ullah I, Farringer MA, Khushu M, Burkhard AY, Hathaway E, Willett BC, Shin SH, Sharma AI, Mallick R, Istvan ES, Martin MC, Harrigan O, Shao KL, Dvorin JD, Hartl DL, Volkman SK, Bopp S, Absalon S, Wirth DF
Induction of broadly neutralizing HIV antibodies by a two-step mechanism informs vaccine design.
1. Science - published May 7, 2026
2. Skelly AN, Gristick HB, Li H, Gavor E, Connell AJ, Kreider EF, Marchitto L, Hogarty MP, Newby ML, Allen JD, Liu W, West AP Jr, Ayyanathan K, Campion MS, Winters K, Gordon CG, Osbaldeston RA, Akeley MJ, Lewis E, Li Y, Singh A, Cruickshank K, Park Y, Zhao C, Li X, Amereh K, Van Itallie E, Carey JW, Albertus A, DeLaitsch AT, Keeffe JR, Lituchy MG, Walsh AA, Morris DJ, Habib R, Bibollet-Ruche F, Mishra N, Avillion G, Koranda NS, Plante SJ, Martella CL, Lora J, Wang EJD, Lewis MG, Martin MA, Nussenzweig MC, Seaman MS, Irvine DJ, Wiehe KJ, Haynes BF, Wagh K, Korber B, Andrabi R, Crispin M, Weissman D, Bjorkman PJ, Hahn BH, Shaw GM
Comprehensive cross-cohort analysis reveals global gut microbiome signatures of celiac disease.
1. Commun Med (Lond) - published May 7, 2026
2. Prendergast PJ, Bishop HV, Herbold CW, Verdu EF, Dobson RCJ, Day AS, Ogilvie OJ
Beyond resolution: Cryo-electron tomography of microbial nanomachines in native host context.
1. Curr Opin Struct Biol - published May 7, 2026
2. Leemburg B, Harastani M, Bezault A, Briegel A
Let there be light: Targeted fluorescent labels illuminate cryo-FIB/ET of synapses.
1. Structure - published May 7, 2026
2. Rothfuss SJ, Zhou Q
Breaking symmetry: Homomeric glycine receptor joins the asymmetric gating club.
1. Structure - published May 7, 2026
2. Wang W
Cryo-EM in enzymology and dynamics.
1. Structure - published May 7, 2026
2. Tsai MD, Wolf M, Chang CM, Chiu W
Fronto-insular circuit mechanisms of accelerated intermittent theta burst stimulation.
1. Cell - published May 7, 2026
2. Johnson SB, Rocks D, Chalençon L, Johnson K, Hassan U, Arefin A, Akgül G, Donatelle A, Asher H, Elbau I, Estrin D, Zhang R, Lenz A, Mikofsky R, Knox C, Han R, Suganthan P, Chowdhury T, Kuang C, Shaver D, Nilchian P, Parekh P, Roshgadol J, DeMarco Garcia N, Wright M, Victoria L, Zebley B, Levitz J, Keller CJ, Boes AD, Liston C
Bile acids accumulate norovirus-like particles and enhance binding to and entry into human enteric epithelial cells.
1. J Virol - published May 6, 2026
2. Hahlin E, Danskog K, Nord S, Becker M, Willekens SMA, Wibom C, Tanner H, Frängsmyr L, Öhlund D, Sandblad L, Lenman A, Arnberg N
Two types of sheathed archaellum structures from Haloarcula marismortui differ in their outer layer architectures.
1. Nat Commun - published May 6, 2026
2. Meshcheryakov VA, Hyun J, Shibata S, Syutkin AS, Pyatibratov MG, Wolf M
Editorial Expression of Concern: Discovery of a BTK/MNK dual inhibitor for lymphoma and leukemia.
1. Leukemia - published May 6, 2026
2. Wu H, Hu C, Wang A, Weisberg EL, Chen Y, Yun CH, Wang W, Liu Y, Liu X, Tian B, Wang J, Zhao Z, Liang Y, Li B, Wang L, Wang B, Chen C, Buhrlage SJ, Qi Z, Zou F, Nonami A, Li Y, Fernandes SM, Adamia S, Stone RM, Galinsky IA, Wang X, Yang G, Griffin JD, Brown JR, Eck MJ, Liu J, Gray NS, Liu Q
Affinity-matured B cell responses neutralizing type-I interferons underlie severe viral infections.
1. Cell - published May 6, 2026
2. Fournier M, Vanderkerken M, Dorgham K, Bastard P, Ahouzi O, Duquerroy S, Nguyen NK, Broutin M, Charlet M, Vandenberghe A, Van Endert P, Bizien L, Da Mata-Jardin O, Ferriño-Iriarte A, Haouz A, Belmondo T, Hüe S, Borghesi A, Rodríguez-Gallego C, Vinh DC, Andreakos E, Haerynck F, Halwani R, Pan-Hammarström Q, Björkström NK, Strunz B, Mogensen TH, COVID Human Genetic Effort, Piralla A, Varchetta S, Freixinet J, Roussel L, Trouillet Assant S, Neven B, Levy R, le Voyer T, Delmonte OM, O'Farrelly C, Rivière J, Amador Borrero B, Servettaz A, Kouyos RD, Kaufmann DE, Crickx E, Michel M, Puel A, Abel L, Luyt CE, Mathian A, Kisand K, Duffy D, Quintana-Murci L, Amoura Z, Hale BG, Weill JC, Casanova JL, Rey FA, Gorochov G, Chappert P, Mahévas M
PPIL2 suppression induces cellular senescence and inhibits proliferation in hepatocellular carcinoma via c-Myc/p21 axis.
1. J Biol Chem - published May 6, 2026
2. Chen X, Zhang Z, Yan Z, Du X, Wang J, Liu X, Hu L, Kuang Z, He K, Zhang J, Han Y
Proton Hopping and Secondary Gating Reveal a Universal Transport Mechanism in a Minimal Bacterial Transporter EmrE.
1. Biophys J - published May 6, 2026
2. Teng D, Brousseau M, Choi JH, Henzler-Wildman KA, Voth GA
Bacillus cereus PelA(DA) is a polysaccharide de-N-acetylase required for Pel-dependent biofilm formation.
1. J Biol Chem - published May 6, 2026
2. Subramanian AS, Le Mauff F, Kitova EN, Pfoh R, Panjalingam M, Wu DY, Gilbert S, Morrison ZA, Jacobsen-Pérez CA, Razvi E, Nitz M, Codée J, Klassen JS, Sheppard DC, Howell PL
DARPins as pan-reactivators of temperature-sensitive p53 cancer mutants.
1. Proc Natl Acad Sci U S A - published May 5, 2026
2. Münick P, Balourdas DI, Funk JS, Yüksel B, Mavridi D, Heftel J, Dreier B, Schaefer JV, Schäfer B, Knapp S, Telatar T, Akgül B, Plückthun A, Stiewe T, Joerger AC, Dötsch V
Cellular responses to FGF1 are modulated by palmitoylation of the docking protein FRS2α.
1. Proc Natl Acad Sci U S A - published May 5, 2026
2. An SJ, Suzuki Y, Mohanty J, Tome F, Lax I, Schlessinger J
Importin-9 recognizes the winged-helix fold of ETS transcription factors to mediate nuclear import.
1. Proc Natl Acad Sci U S A - published May 5, 2026
2. McConville M, Lankford K, Bernardes NE, Walterscheid A, Valadez C, Niesman A, Chook YM, Liszczak G
Genotype-structure-phenotype correlations define divergent natural history in early-onset spastic paraplegia type 4.
1. Brain - published May 5, 2026
2. Alecu JE, Schierbaum LM, Tam A, Quiroz V, Bernardi K, Yang K, Roller JR, Döbler-Neumann M, Rattay TW, González-Salazar C, Zehr EA, Skorohodovs D, Rong J, Carty S, Battaglia N, Lee S, Moon J, Christie M, Roll-Mecak A, França MC Jr, Schüle R, Schöls LJ, Ebrahimi-Fakhari D
Author Correction: Sirtuin 2 inhibits global protein synthesis via Rheb-GTPase degradation.
1. EMBO Rep - published May 5, 2026
2. Shrama A, Zi Y, Pandit AS, Jha K, Sinha VK, Nagesh D, Shivanaiah B, Ravi V, Ghosh S, Khan D, Prabhashankar AB, Sumi TS, Rajpurohit S, Ningaraju S, Raghu S, Srivastava A, Singh M, Lin H, Sundaresan NR
Disrupted molecular glue complex drives RAS inhibitor resistance.
1. Cell - published May 5, 2026
2. Sang B, Ye LF, Fu Z, Pourfarjam Y, Cuevas-Navarro A, Fan S, Hu F, Washington A, Rodriguez DJ, Vides A, Kar S, Ahler E, Lin KK, Hegde A, Smith JAM, Wolpin BM, Punekar SR, Spira AI, Garrido-Laguna I, Hong DS, Dar AC, Yaeger R, Arbour KC, Lito P
(1)H, (13)C, (15)N backbone chemical shift assignments and relaxation analysis of the single and tandem RRMs of the human serine-arginine rich splicing factor 6 (SRSF6).
1. J Magn Reson - published May 5, 2026
2. von Ehr J, Schlundt A
Dominant-negative PSMB10 disrupts immunoproteasome assembly and leads to transient T lymphopenia.
1. J Hum Immun - published May 4, 2026
2. Ghosh S, Wang Y, Schultheiss C, Borkhardt A, Dafun AS, Knipp L, Marwitz S, Ehl S, Soulard C, Haddad E, Dey D, Evans G, Golwala ZM, Bennstein SB, Laws HJ, Rohlfs M, Magg T, Binder M, Kreins AY, Bousquet MP, Marcoux J, Klein C, Conn GL, Meiners S, Hauck F
VUStruct: A compute pipeline for high throughput and personalized structural biology.
1. PLoS Comput Biol - published May 4, 2026
2. Moth CW, Sheehan JH, Al Mamun A, Sivley RM, Gulsevin A, Rinker DC, Mchaourab ZF, Undiagnosed Diseases Network, Capra JA, Meiler J
Transcriptional transactivation turns human iPSC-derived macrophages into an adenovirus-producing cell state.
1. J Virol - published May 4, 2026
2. Suomalainen M, Haenseler W, Kolibius J, Plückthun A, Hearing P, Greber UF
Emergence of specific binding and catalysis from a designed generalist binding protein.
1. Nat Chem - published May 4, 2026
2. Chen Y, Bhattacharya S, Bergmann L, Correy GJ, Tan SK, Hou K, Biel JT, Lu L, Bakanas I, Gestwicki JE, Volkov AN, Korendovych IV, Polizzi NF, Fraser JS, DeGrado WF
ICP1 bacteriophage treatment antagonizes colonization of the zebrafish larval intestine by Vibrio cholerae.
1. Microbiol Spectr - published May 4, 2026
2. Sidi Mabrouk A, Depelteau JS, Foini C, Kempff A, Jonker S, Brenzinger S, Limpens R, Majrouh M, Meijer AH, Briegel A
Ultrastructural insights into the polar tube invasion organelle from microsporidian parasites.
1. Curr Opin Microbiol - published May 4, 2026
2. Watson PR, Ekiert DC, Bhabha G
Cigarette smoke induces FASN-dependent fatty acid metabolic rewiring to drive bladder cancer progression.
1. Cancer Lett - published May 4, 2026
2. Amara CS, Piyarathna DWB, Kamal AHM, Chan YS, Kami Reddy KR, Ambati CSR, Hassan MK, Shriwas P, Gandhi T, Jain A, Gangnus T, Popli P, Borkar R, Kang SW, Summers SL, Putluri V, Grimm SL, Venkatesh S, Song N, Seeley EH, Hedlich-Dwyer J, Chen SH, Mahajan NP, Jain AK, Dobrolecki LE, Wells GA, Villanueva H, Li J, Liu X, Bollag RJ, Malovannaya A, Jung SY, Lee HS, Asangani IA, Terris MK, Creighton CJ, Ballester LY, Karanam B, Liu S, Lee M, Raju RR, Siddiqui MM, Eberlin LS, Kommagani R, Sreekumar A, Gao J, Young NL, Hodges HC, Coarfa C, Gassman NR, Lerner SP, Lotan Y, Putluri N
pH-mediated activation of the lysosomal arginine sensor SLC38A9.
1. FEBS Lett - published May 3, 2026
2. Mu X, Her AS, Gonen T
Crystal structures of the mycolic acid methyl transferase 1 (MmaA1) from Mycobacterium tuberculosis in the apo-form and in complex with different cofactors reveal unique features for substrate binding.
1. J Biomol Struct Dyn - published May 1, 2026
2. Chaudhary B, Kobakhidze G, Wachelder L, Mazumdar PA, Dong G, Madhurantakam C
Radiation damage in sub-Ångström resolution macromolecular crystallography: a low-dose study.
1. Acta Crystallogr D Struct Biol - published May 1, 2026
2. Bourenkov G, Paknia E, Flensburg C, Fogh R, Keller P, Vonrhein C, Bricogne G, Chari A
BSxCuBE-Web - a web application for bioSAXS high-throughput collection and experimental control.
1. J Synchrotron Radiat - published May 1, 2026
2. Florial JB, Oscarsson M, Beteva A, Fisher S, Kieffer J, Calio A, Fisher H, Brennich M, Moussaoui D, Popov A, Soler-Lopez M, Pernot P, Tully MD, McCarthy AA
Making sense of invisible densities in single-particle cryo-EM.
1. IUCrJ - published May 1, 2026
2. Lin X, Cheng Y
A cryo-EM processing pipeline for microtubules using CryoSPARC.
1. Acta Crystallogr D Struct Biol - published May 1, 2026
2. Zhang D, Muñoz-Hernández H, Filipcik P, Sejwal K, Xu Y, Choi SR, Steinmetz MO, Wieczorek M
PARP4 ADP-ribosylates PIDD1 to complete a phospho/SUMO/PAR-ylation cascade that orchestrates PIDDosome assembly.
1. Sci Adv - published May 1, 2026
2. Shah RB, Li Y, Person A, Frigon L, Ðukić N, Kini E, Chen R, Pascal JM, Cohen MS, Ahel I, Haley JD, Sidi S
TrkB/mGluR5 cross-talk underlies a synaptic metaplasticity mechanism of ketamine.
1. Sci Adv - published May 1, 2026
2. Arefin A, Kim J, Chakraborty MP, Martinelli S, Bai B, Lee FS, Levitz J
Regulation of antiviral and antitumor immunity by the BRCA1 pseudogene in human cancers.
1. Proc Natl Acad Sci U S A - published May 1, 2026
2. Han YJ, Zhang J, Shariff M, Wu S, Khramtsova G, Nguyen LC, Peiffer DS, Li N, Lewicka A, Moore M, Piccirilli JA, Olopade OI
A molecular timer couples organism-wide temporal identity to developmental checkpoints.
1. Proc Natl Acad Sci U S A - published May 1, 2026
2. Wu P, Wang J, Pryor B, Valentino I, Ritter DF, Loel K, Yarychkivska O, Shaham S, Kinney J, Ercan S, Joshua-Tor L, Hammell CM
How endosomal PIKfyve inhibition prevents viral membrane fusion and entry.
1. Proc Natl Acad Sci U S A - published May 1, 2026
2. Chow N, Scanavachi G, Saminathan A, Kirchhausen T
Inflammasome adaptor protein ASC is a mechanistic checkpoint in IL-1β maturation.
1. Proc Natl Acad Sci U S A - published May 1, 2026
2. Saha G, Anchi P, Wang R, Biondo A, Meyer S, Kondragunta V, Luchsinger LL, Syed I, Sharif H, Wu H, Giri Magupalli V