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111 Member Publications for May 2026

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Morning glucagon disrupts insulin induced hepatic metabolic memory and subsequent afternoon glucose metabolism in canines.
1. Front Endocrinol (Lausanne) - published May 15, 2026
2. Waterman HL, Smith MS, Farmer B, Yankey K, Bosma KJ, O'Brien RM, Claxton DP, Howard T, Kraft G, Cherrington AD, Edgerton DS
CRISPR base editor screening identifies spectrum of MEN1 mutations impacting menin inhibitors in clinical trials.
1. Nat Commun - published May 9, 2026
2. Bourgeois W, Rice HE, Wenge DV, Perner F, Yue H, Regalado BD, Wan G, Schroeder JC, Sommerschield A, Hatton C, Singh S, Singh S, Bijpuria S, McKeever BM, Miller WH, Safer JF, Iqbal S, Perry JA, Fischer ES, Doench JG, McGeehan GM, Cutler JA, Armstrong SA
Tunable TriPcides suppress virulence factor secretion during Staphylococcus aureus infection and kill dormant cells.
1. Sci Adv - published May 8, 2026
2. Tükenmez H, Nye TM, Singh P, Mychack A, Bonde M, Hickerson S, Obernuefemann CLP, Pinkner JS, Zhu S, Sarkar S, Bharate JB, van der Lingen I, Ntuyenm AQ, Rao VUB, Lindgren AEG, Klein H, Zou Z, Dodson KW, Walker S, Mateus A, Johansson J, Caparon MG, Almqvist F, Hultgren SJ
DNA binding and lesion recognition by the bacterial interstrand DNA crosslink glycosylase AlkX.
1. EMBO Rep - published May 8, 2026
2. Cai Y, Kunkle DE, Edinbugh MD, Bradley NP, Skaar EP, Eichman BF
Biolayer Interferometry for Investigating Membrane Protein-Inhibitor Binding: TACAN Mutant and GsMTx4 As a Model System.
1. J Vis Exp - published May 8, 2026
2. Mazher M, Michell B, Rouiller I
PI3K Regulates Wild-type RAS Signaling to Confer Resistance to KRAS Inhibition.
1. Cancer Res - published May 7, 2026
2. Ge X, Singh J, Li W, Markham CS, Ruiz CF, Stites EC, Bhattacharyya M, Liu Y, Muzumdar MD
Comprehensive cross-cohort analysis reveals global gut microbiome signatures of celiac disease.
1. Commun Med (Lond) - published May 7, 2026
2. Prendergast PJ, Bishop HV, Herbold CW, Verdu EF, Dobson RCJ, Day AS, Ogilvie OJ
Induction of broadly neutralizing HIV antibodies by a two-step mechanism informs vaccine design.
1. Science - published May 7, 2026
2. Skelly AN, Gristick HB, Li H, Gavor E, Connell AJ, Kreider EF, Marchitto L, Hogarty MP, Newby ML, Allen JD, Liu W, West AP Jr, Ayyanathan K, Campion MS, Winters K, Gordon CG, Osbaldeston RA, Akeley MJ, Lewis E, Li Y, Singh A, Cruickshank K, Park Y, Zhao C, Li X, Amereh K, Van Itallie E, Carey JW, Albertus A, DeLaitsch AT, Keeffe JR, Lituchy MG, Walsh AA, Morris DJ, Habib R, Bibollet-Ruche F, Mishra N, Avillion G, Koranda NS, Plante SJ, Martella CL, Lora J, Wang EJD, Lewis MG, Martin MA, Nussenzweig MC, Seaman MS, Irvine DJ, Wiehe KJ, Haynes BF, Wagh K, Korber B, Andrabi R, Crispin M, Weissman D, Bjorkman PJ, Hahn BH, Shaw GM
Cellular and molecular basis of PfCoronin function in artemisinin resistance in Plasmodium falciparum.
1. Nat Commun - published May 7, 2026
2. Ullah I, Farringer MA, Khushu M, Burkhard AY, Hathaway E, Willett BC, Shin SH, Sharma AI, Mallick R, Istvan ES, Martin MC, Harrigan O, Shao KL, Dvorin JD, Hartl DL, Volkman SK, Bopp S, Absalon S, Wirth DF
Beyond resolution: Cryo-electron tomography of microbial nanomachines in native host context.
1. Curr Opin Struct Biol - published May 7, 2026
2. Leemburg B, Harastani M, Bezault A, Briegel A
Fronto-insular circuit mechanisms of accelerated intermittent theta burst stimulation.
1. Cell - published May 7, 2026
2. Johnson SB, Rocks D, Chalençon L, Johnson K, Hassan U, Arefin A, Akgül G, Donatelle A, Asher H, Elbau I, Estrin D, Zhang R, Lenz A, Mikofsky R, Knox C, Han R, Suganthan P, Chowdhury T, Kuang C, Shaver D, Nilchian P, Parekh P, Roshgadol J, DeMarco Garcia N, Wright M, Victoria L, Zebley B, Levitz J, Keller CJ, Boes AD, Liston C
Cryo-EM in enzymology and dynamics.
1. Structure - published May 7, 2026
2. Tsai MD, Wolf M, Chang CM, Chiu W
Breaking symmetry: Homomeric glycine receptor joins the asymmetric gating club.
1. Structure - published May 7, 2026
2. Wang W
Let there be light: Targeted fluorescent labels illuminate cryo-FIB/ET of synapses.
1. Structure - published May 7, 2026
2. Rothfuss SJ, Zhou Q
Editorial Expression of Concern: Discovery of a BTK/MNK dual inhibitor for lymphoma and leukemia.
1. Leukemia - published May 6, 2026
2. Wu H, Hu C, Wang A, Weisberg EL, Chen Y, Yun CH, Wang W, Liu Y, Liu X, Tian B, Wang J, Zhao Z, Liang Y, Li B, Wang L, Wang B, Chen C, Buhrlage SJ, Qi Z, Zou F, Nonami A, Li Y, Fernandes SM, Adamia S, Stone RM, Galinsky IA, Wang X, Yang G, Griffin JD, Brown JR, Eck MJ, Liu J, Gray NS, Liu Q
Two types of sheathed archaellum structures from Haloarcula marismortui differ in their outer layer architectures.
1. Nat Commun - published May 6, 2026
2. Meshcheryakov VA, Hyun J, Shibata S, Syutkin AS, Pyatibratov MG, Wolf M
Bile acids accumulate norovirus-like particles and enhance binding to and entry into human enteric epithelial cells.
1. J Virol - published May 6, 2026
2. Hahlin E, Danskog K, Nord S, Becker M, Willekens SMA, Wibom C, Tanner H, Frängsmyr L, Öhlund D, Sandblad L, Lenman A, Arnberg N
Affinity-matured B cell responses neutralizing type-I interferons underlie severe viral infections.
1. Cell - published May 6, 2026
2. Fournier M, Vanderkerken M, Dorgham K, Bastard P, Ahouzi O, Duquerroy S, Nguyen NK, Broutin M, Charlet M, Vandenberghe A, Van Endert P, Bizien L, Da Mata-Jardin O, Ferriño-Iriarte A, Haouz A, Belmondo T, Hüe S, Borghesi A, Rodríguez-Gallego C, Vinh DC, Andreakos E, Haerynck F, Halwani R, Pan-Hammarström Q, Björkström NK, Strunz B, Mogensen TH, COVID Human Genetic Effort, Piralla A, Varchetta S, Freixinet J, Roussel L, Trouillet Assant S, Neven B, Levy R, le Voyer T, Delmonte OM, O'Farrelly C, Rivière J, Amador Borrero B, Servettaz A, Kouyos RD, Kaufmann DE, Crickx E, Michel M, Puel A, Abel L, Luyt CE, Mathian A, Kisand K, Duffy D, Quintana-Murci L, Amoura Z, Hale BG, Weill JC, Casanova JL, Rey FA, Gorochov G, Chappert P, Mahévas M
Proton Hopping and Secondary Gating Reveal a Universal Transport Mechanism in a Minimal Bacterial Transporter EmrE.
1. Biophys J - published May 6, 2026
2. Teng D, Brousseau M, Choi JH, Henzler-Wildman KA, Voth GA
Bacillus cereus PelA(DA) is a polysaccharide de-N-acetylase required for Pel-dependent biofilm formation.
1. J Biol Chem - published May 6, 2026
2. Subramanian AS, Le Mauff F, Kitova EN, Pfoh R, Panjalingam M, Wu DY, Gilbert S, Morrison ZA, Jacobsen-Pérez CA, Razvi E, Nitz M, Codée J, Klassen JS, Sheppard DC, Howell PL
PPIL2 suppression induces cellular senescence and inhibits proliferation in hepatocellular carcinoma via c-Myc/p21 axis.
1. J Biol Chem - published May 6, 2026
2. Chen X, Zhang Z, Yan Z, Du X, Wang J, Liu X, Hu L, Kuang Z, He K, Zhang J, Han Y
DARPins as pan-reactivators of temperature-sensitive p53 cancer mutants.
1. Proc Natl Acad Sci U S A - published May 5, 2026
2. Münick P, Balourdas DI, Funk JS, Yüksel B, Mavridi D, Heftel J, Dreier B, Schaefer JV, Schäfer B, Knapp S, Telatar T, Akgül B, Plückthun A, Stiewe T, Joerger AC, Dötsch V
Cellular responses to FGF1 are modulated by palmitoylation of the docking protein FRS2α.
1. Proc Natl Acad Sci U S A - published May 5, 2026
2. An SJ, Suzuki Y, Mohanty J, Tome F, Lax I, Schlessinger J
Importin-9 recognizes the winged-helix fold of ETS transcription factors to mediate nuclear import.
1. Proc Natl Acad Sci U S A - published May 5, 2026
2. McConville M, Lankford K, Bernardes NE, Walterscheid A, Valadez C, Niesman A, Chook YM, Liszczak G
Genotype-structure-phenotype correlations define divergent natural history in early-onset spastic paraplegia type 4.
1. Brain - published May 5, 2026
2. Alecu JE, Schierbaum LM, Tam A, Quiroz V, Bernardi K, Yang K, Roller JR, Döbler-Neumann M, Rattay TW, González-Salazar C, Zehr EA, Skorohodovs D, Rong J, Carty S, Battaglia N, Lee S, Moon J, Christie M, Roll-Mecak A, França MC Jr, Schüle R, Schöls LJ, Ebrahimi-Fakhari D
Author Correction: Sirtuin 2 inhibits global protein synthesis via Rheb-GTPase degradation.
1. EMBO Rep - published May 5, 2026
2. Shrama A, Zi Y, Pandit AS, Jha K, Sinha VK, Nagesh D, Shivanaiah B, Ravi V, Ghosh S, Khan D, Prabhashankar AB, Sumi TS, Rajpurohit S, Ningaraju S, Raghu S, Srivastava A, Singh M, Lin H, Sundaresan NR
Disrupted molecular glue complex drives RAS inhibitor resistance.
1. Cell - published May 5, 2026
2. Sang B, Ye LF, Fu Z, Pourfarjam Y, Cuevas-Navarro A, Fan S, Hu F, Washington A, Rodriguez DJ, Vides A, Kar S, Ahler E, Lin KK, Hegde A, Smith JAM, Wolpin BM, Punekar SR, Spira AI, Garrido-Laguna I, Hong DS, Dar AC, Yaeger R, Arbour KC, Lito P
(1)H, (13)C, (15)N backbone chemical shift assignments and relaxation analysis of the single and tandem RRMs of the human serine-arginine rich splicing factor 6 (SRSF6).
1. J Magn Reson - published May 5, 2026
2. von Ehr J, Schlundt A
Structure and function of IWS1 in transcription elongation.
1. Nucleic Acids Res - published May 5, 2026
2. Syau D, Steinruecke F, Roth S, Schmid E, Adelman K, Walter JC, Farnung L
Dominant-negative PSMB10 disrupts immunoproteasome assembly and leads to transient T lymphopenia.
1. J Hum Immun - published May 4, 2026
2. Ghosh S, Wang Y, Schultheiss C, Borkhardt A, Dafun AS, Knipp L, Marwitz S, Ehl S, Soulard C, Haddad E, Dey D, Evans G, Golwala ZM, Bennstein SB, Laws HJ, Rohlfs M, Magg T, Binder M, Kreins AY, Bousquet MP, Marcoux J, Klein C, Conn GL, Meiners S, Hauck F
ICP1 bacteriophage treatment antagonizes colonization of the zebrafish larval intestine by Vibrio cholerae.
1. Microbiol Spectr - published May 4, 2026
2. Sidi Mabrouk A, Depelteau JS, Foini C, Kempff A, Jonker S, Brenzinger S, Limpens R, Majrouh M, Meijer AH, Briegel A
Emergence of specific binding and catalysis from a designed generalist binding protein.
1. Nat Chem - published May 4, 2026
2. Chen Y, Bhattacharya S, Bergmann L, Correy GJ, Tan SK, Hou K, Biel JT, Lu L, Bakanas I, Gestwicki JE, Volkov AN, Korendovych IV, Polizzi NF, Fraser JS, DeGrado WF
Transcriptional transactivation turns human iPSC-derived macrophages into an adenovirus-producing cell state.
1. J Virol - published May 4, 2026
2. Suomalainen M, Haenseler W, Kolibius J, Plückthun A, Hearing P, Greber UF
VUStruct: A compute pipeline for high throughput and personalized structural biology.
1. PLoS Comput Biol - published May 4, 2026
2. Moth CW, Sheehan JH, Al Mamun A, Sivley RM, Gulsevin A, Rinker DC, Mchaourab ZF, Undiagnosed Diseases Network, Capra JA, Meiler J
Ultrastructural insights into the polar tube invasion organelle from microsporidian parasites.
1. Curr Opin Microbiol - published May 4, 2026
2. Watson PR, Ekiert DC, Bhabha G
Cigarette smoke induces FASN-dependent fatty acid metabolic rewiring to drive bladder cancer progression.
1. Cancer Lett - published May 4, 2026
2. Amara CS, Piyarathna DWB, Kamal AHM, Chan YS, Kami Reddy KR, Ambati CSR, Hassan MK, Shriwas P, Gandhi T, Jain A, Gangnus T, Popli P, Borkar R, Kang SW, Summers SL, Putluri V, Grimm SL, Venkatesh S, Song N, Seeley EH, Hedlich-Dwyer J, Chen SH, Mahajan NP, Jain AK, Dobrolecki LE, Wells GA, Villanueva H, Li J, Liu X, Bollag RJ, Malovannaya A, Jung SY, Lee HS, Asangani IA, Terris MK, Creighton CJ, Ballester LY, Karanam B, Liu S, Lee M, Raju RR, Siddiqui MM, Eberlin LS, Kommagani R, Sreekumar A, Gao J, Young NL, Hodges HC, Coarfa C, Gassman NR, Lerner SP, Lotan Y, Putluri N
Standardising definitions, endpoints, and reporting parameters for clinical studies of stereotactic body radiation therapy in bone metastases: An international Delphi consensus.
1. Eur J Cancer - published May 4, 2026
2. Lee SF, Wong HCY, Oldenburger E, Raman S, Marta GN, Chan AW, Rades D, van der Linden YM, van der Velden JM, Nguyen QN, Choi JI, Hircock C, Doccioli C, Cosma C, Caini S, Rembielak A, Vassiliou V, Bonomo P, Alcorn S, Johnstone C, Simone CB 2nd, Hoskin PJ, Chow E, Ryu S
pH-mediated activation of the lysosomal arginine sensor SLC38A9.
1. FEBS Lett - published May 3, 2026
2. Mu X, Her AS, Gonen T
Membrane protein structure and dynamics probed by MicroED.
1. Biochem Soc Trans - published May 2, 2026
2. Paz O, Gonen T
TAM receptor tyrosine kinases as potential mediators of the non-lytic spread of non-enveloped viruses.
1. Biochem Soc Trans - published May 2, 2026
2. Moran SJ, Starbird CA
A functional map of the human intrinsically disordered proteome.
1. Proc Natl Acad Sci U S A - published May 2, 2026
2. Pritišanac I, Alderson TR, Kolarić Đ, Zarin T, Xie S, Lu A, Alam A, Maqsood A, Youn JY, Forman-Kay JD, Moses AM
Visualizing the mechanism of quinol oxidation and inhibition of a bd-type oxidase using cryo-EM.
1. Sci Adv - published May 2, 2026
2. van der Velden TT, Kayastha K, Pelser F, Brünle S, Jeuken LJC
Peripheral Myelin Protein-22 and Its Prominence in Charcot-Marie-Tooth Disease.
1. Chem Rev - published May 2, 2026
2. Sanders CR, Carter BD, Wilkinson MC, Li GC, Stefanski KM
A universal Fab targeting a conserved U1A-RNA epitope for RNA structure determination by cryo-EM.
1. Nucleic Acids Res - published May 2, 2026
2. Filippova EV, Krochmal D, Mukherjee S, Piccirilli JA, Kossiakoff AA
Engineering NRas palmitoylation to hook zDHHC inhibitors.
1. Cell Chem Biol - published May 2, 2026
2. Rana MS, Banerjee A
Use of Human Dose Prediction Metrics to Enable Discovery of AZD3470, an MTA-Cooperative PRMT5 Inhibitor in Clinical Evaluation.
1. J Med Chem - published May 2, 2026
2. Smith JM, Barlaam B, Beattie D, Bradshaw L, Chan HM, Cooke SL, Cronin A, Cumming I, Dean E, Debreczeni JÉ, Barco Barrantes ID, Ferguson D, Gianni D, Grondine M, Lynch JT, McWilliams L, Moore S, Raubo P, Qu Y, Robb GR, Tan L, Urosevic J, Vazquez-Chantada M, Wang P
Protocol for an in vivo CRISPR screen for germinal center B cells in mice using ecotropic retrovirus.
1. STAR Protoc - published May 2, 2026
2. Hong JP, Nussenzweig MC
Automated deep learning model for predicting pathological complete response in rectal cancer: A tool to organ-preserving strategies.
1. Int J Colorectal Dis - published May 2, 2026
2. J MA, F LM, D MV, L PS, I PL, A GS, N TL, B CP, M RC, G LA, M M, V PM
Biophysical characterization of Ebola VP35 protein binding to host Mindbomb protein 2.
1. J Mol Biol - published May 2, 2026
2. Kuang XC, Uwase G, Wagner ND, Gross M, Leung DW, Amarasinghe GK
The folding pathway of prothrombin.
1. J Thromb Haemost - published May 2, 2026
2. Stojanovski BM, Di Cera E
Recognition and silencing of a new transposable element.
1. Nat Commun - published May 2, 2026
2. Salvi L, Yan Y, Halic M
A Rahman Syndrome mutation in histone H1.4 disrupts chromatin compaction and phase separation.
1. Nat Commun - published May 2, 2026
2. Boopathi R, Garcia-Saez I, Turunç S, Lone IN, Kumar A, Abu Alhaija AA, Hayes JJ, Bednar J, Diril MK, Iliev D, Gospodinov A, Le Roy A, Skoufias D, Angelov D, Hamiche A, Kale S, Dimitrov S, Petosa C
Targeting Hyaluronan Signaling Overcomes Primary Effusion Lymphoma Cells Resistance to Rapamycin.
1. Biol Proced Online - published May 2, 2026
2. Chen J, Qin M, Fan J, Mu S, Dai L, Qin Z
EGFR S442 ectodomain mutation confers cetuximab resistance that can be overcome by ERBB2 blockade with trastuzumab-deruxtecan.
1. Cancer Lett - published May 2, 2026
2. Harmych SJ, Joshi N, Tanaka H, Bogatcheva G, Ramirez MA, Graves-Deal R, Tydings CW, Elia MT, Mueller HRL, Silvestri IM, Ti Ning K, Wahoski CC, Sievers CK, Higginbotham JN, Irudayam MJ, Revetta FL, Zhao Z, Franklin JL, Yilma B, O'Grady TM, Fragkogianni S, Ciampricotti M, Washington MK, Guo X, Lovly CM, Walker AS, Meiler J, Mudumbi KC, Liu Q, Coffey RJ, Rosenthal E, Singh B
Pontocerebellar Hypoplasia linked mutations of the deadenylase Target of EGR1 (TOE1) impair thermal stability, ribonuclease activity, and oligomerization.
1. J Biol Chem - published May 2, 2026
2. Zavala L, Sobien M, Hayne CK
Mechanistic basis of teichoic acid transport by a gatekeeper flippase.
1. Nat Commun - published May 2, 2026
2. Cebrero G, Chidananda AH, Cester E, Dénéréaz J, Demir ES, Mathew AT, Bhowmik DR, de Capitani M, Reymond JL, Kannan N, Avci FY, Veening JW, Mehdipour AR, Perez C
Mapping the avoid-ome: a systematic open-science approach to predictive ADMET.
1. Nat Commun - published May 2, 2026
2. Fraser JS, Edgar S, Handly LN, Kosuri S, Chodera JD, Murcko M, Walters WP
AreTomoLive: automated reconstruction of comprehensively corrected and denoised cryo-electron tomograms in real time and at high throughput.
1. Nat Methods - published May 2, 2026
2. Peck A, Yu Y, Paraan M, Kimanius D, Ermel UH, Hutchings J, Schwartz J, Serwas D, Siems H, Hill NS, Ali M, Peukes J, Greenan GA, Sheu SH, Montabana EA, Carragher B, Potter CS, Agard DA, Zheng S
An appendiceal cancer organoid biobank identifies phenotypic evolution and druggable dependencies of peritoneal carcinomatosis.
1. Dev Cell - published May 2, 2026
2. Mahmoud A, Sukhwa C, Giarrizzo M, Choi PH, Pintar J, Walch H, Zhao N, Bermeo J, Chung S, Raghavan M, Bapat S, Jiang Q, Meredith J, Firat C, Cercek A, Foote MB, Schultz N, Chatila WK, Nash GM, Shia J, Sanchez-Vega F, Larson S, Dar AC, Rosen N, Karagkounis G, Ganesh K
SARS-CoV-2 5'-UTR stem-loops activate the antiviral protein oligoadenylate synthetase 1 (OAS1).
1. J Biol Chem - published May 2, 2026
2. Oviedo A, Bair CR, Vasilakopoulos AP, Regis K, Vanlnsberghe D, Lowen AC, Conn GL
Structural basis for RISC assembly of human Argonaute2.
1. Mol Cell - published May 2, 2026
2. Zhang H, Adhav VA, Kehling AC, Savidge A, Shen Z, Fu TM, Nakanishi K
Membrane bridges and nanodomain partitioning govern membrane protein targeting to lipid droplets.
1. Nat Cell Biol - published May 2, 2026
2. Mizrak A, Kæstel-Hansen J, Matthias J, Harper JW, Hatzakis NS, Farese RV Jr, Walther TC
Expedient single-round selection of hyper-modified aptamer targeting insulin receptor from over-represented dually nucleobase-modified DNA libraries.
1. Nat Commun - published May 2, 2026
2. Franco-Urquijo PA, Ondruš M, Kurfürst J, Škerlová J, Selicharová I, Mužíková Čechová L, Šváchová H, Semerádtová A, Filimoněnko A, Fejfarová A, Homola J, Kouba T, Hocek M
Molecular basis of type VI secretion system effector loading.
1. Nat Microbiol - published May 2, 2026
2. Paracuellos P, Bexter A, Patkowski JB, Kelly SD, Omelchenko O, Macé K, Ilangovan A, Subramoni S, Whitney JC, Filloux A, Costa TRD
Channeling teamwork: ATP and lipids cooperate to gate P2X receptors.
1. Sci Adv - published May 2, 2026
2. Bosmans F, Kawate T
Substrate selectivity of the human RNA m(5)C methyltransferase NSUN2.
1. Nature - published May 2, 2026
2. Canepa J, Ruiz-Arroyo VM, Schlamowitz NS, Nam Y
A protein interactome for the last eukaryotic common ancestor illuminates the biochemical basis of modern genetic diseases.
1. Cell Genom - published May 2, 2026
2. Cox RM, Papoulas O, Shril S, Lee C, Gardner TP, Ansari ZT, Battenhouse AM, Lee M, Drew K, McWhite CD, Yang D, Leggere JC, Durand D, Hildebrandt F, Wallingford JB, Marcotte EM
Rheinheimera sp. T2C2 Bacterial Biofilm for Bioremediation of Cobalt(II).
1. ACS Appl Polym Mater - published May 2, 2026
2. van Wijngaarden EW, Brunette MP, Goetsch AG, Brito IL, Hershey DM, Silberstein MN
Time to HIV rebound after infusion of long-acting broadly neutralising antibodies 3BNC117-LS and 10-1074-LS and analytical treatment interruption (the RIO trial): a double-blind, randomised, placebo-controlled trial.
1. Lancet HIV - published May 2, 2026
2. Lee MJ, Cherrill LR, Zacharopoulou P, Collins S, Fumagalli M, Falaschetti E, Altaf M, Tipoe T, Godakandaarachi P, Fox J, Uriel A, Clarke A, Loes SK, Pett S, Boffito M, Whitlock G, Søgaard OS, Ring K, Mangawa I, Gohil J, Elliott T, Nielsen H, Gunst JD, Orkin C, Sutherland R, Hamzah L, Cicconi P, Taylor GP, Ujetz J, Jahan I, Brown H, Robinson N, Fletcher S, Box H, Seaton KE, Tomaras GD, Ackerman ME, Weiner JA, Kaczynska A, Bittar C, Horowitz J, Nussenzweig MC, Caskey M, Frater J, Fidler S, RIO Study Team
Crystal structures of the mycolic acid methyl transferase 1 (MmaA1) from Mycobacterium tuberculosis in the apo-form and in complex with different cofactors reveal unique features for substrate binding.
1. J Biomol Struct Dyn - published May 1, 2026
2. Chaudhary B, Kobakhidze G, Wachelder L, Mazumdar PA, Dong G, Madhurantakam C
Radiation damage in sub-Ångström resolution macromolecular crystallography: a low-dose study.
1. Acta Crystallogr D Struct Biol - published May 1, 2026
2. Bourenkov G, Paknia E, Flensburg C, Fogh R, Keller P, Vonrhein C, Bricogne G, Chari A
BSxCuBE-Web - a web application for bioSAXS high-throughput collection and experimental control.
1. J Synchrotron Radiat - published May 1, 2026
2. Florial JB, Oscarsson M, Beteva A, Fisher S, Kieffer J, Calio A, Fisher H, Brennich M, Moussaoui D, Popov A, Soler-Lopez M, Pernot P, Tully MD, McCarthy AA
Making sense of invisible densities in single-particle cryo-EM.
1. IUCrJ - published May 1, 2026
2. Lin X, Cheng Y
A cryo-EM processing pipeline for microtubules using CryoSPARC.
1. Acta Crystallogr D Struct Biol - published May 1, 2026
2. Zhang D, Muñoz-Hernández H, Filipcik P, Sejwal K, Xu Y, Choi SR, Steinmetz MO, Wieczorek M
PARP4 ADP-ribosylates PIDD1 to complete a phospho/SUMO/PAR-ylation cascade that orchestrates PIDDosome assembly.
1. Sci Adv - published May 1, 2026
2. Shah RB, Li Y, Person A, Frigon L, Ðukić N, Kini E, Chen R, Pascal JM, Cohen MS, Ahel I, Haley JD, Sidi S
TrkB/mGluR5 cross-talk underlies a synaptic metaplasticity mechanism of ketamine.
1. Sci Adv - published May 1, 2026
2. Arefin A, Kim J, Chakraborty MP, Martinelli S, Bai B, Lee FS, Levitz J
Regulation of antiviral and antitumor immunity by the BRCA1 pseudogene in human cancers.
1. Proc Natl Acad Sci U S A - published May 1, 2026
2. Han YJ, Zhang J, Shariff M, Wu S, Khramtsova G, Nguyen LC, Peiffer DS, Li N, Lewicka A, Moore M, Piccirilli JA, Olopade OI
A molecular timer couples organism-wide temporal identity to developmental checkpoints.
1. Proc Natl Acad Sci U S A - published May 1, 2026
2. Wu P, Wang J, Pryor B, Valentino I, Ritter DF, Loel K, Yarychkivska O, Shaham S, Kinney J, Ercan S, Joshua-Tor L, Hammell CM
Inflammasome adaptor protein ASC is a mechanistic checkpoint in IL-1β maturation.
1. Proc Natl Acad Sci U S A - published May 1, 2026
2. Saha G, Anchi P, Wang R, Biondo A, Meyer S, Kondragunta V, Luchsinger LL, Syed I, Sharif H, Wu H, Giri Magupalli V
How endosomal PIKfyve inhibition prevents viral membrane fusion and entry.
1. Proc Natl Acad Sci U S A - published May 1, 2026
2. Chow N, Scanavachi G, Saminathan A, Kirchhausen T
A molecular lattice reinforces the sperm head-tail junction.
1. Proc Natl Acad Sci U S A - published May 1, 2026
2. Wood AJ, Liu P, Tang S
Assessment of Alphafold Protein Models for Small-Molecule Ligand Docking versus Co-Folding.
1. J Chem Inf Model - published May 1, 2026
2. Maidanik H, Lazou M, Bajaj R, Sarwar R, Ziaee O, Vajda S, Joseph-McCarthy D
Diverse paths to broadly neutralizing antibody escape among HIV-1 strains.
1. Nat Microbiol - published May 1, 2026
2. Stabell AC, Lee S, Park DJ, Lavine CL, Espinosa SM, Baharani VA, Patejak R, Nussenzweig MC, Caskey M, Seaman MS, Bieniasz PD, Hatziioannou T
INAAC: An affinity chromatography strategy enabling characterization and quantification of influenza neuraminidase antigens in vaccines.
1. J Biol Chem - published May 1, 2026
2. Kang H, Borowska A, Kanai T, Gao J, Yu H, Chen X, Gorman J, Slotboom DJ, Daniels R
HIV-1 envelope glycoprotein modulates CXCR4 clustering and dynamics on the T cell membrane.
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Synergistic alleviation of salinity stress in tomato: unraveling the physiological, biochemical, and antioxidant mechanisms modulated by manganese nanoparticles and chitosan.
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