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110 Member Publications for January 2017

Structural insight into an evolutionarily ancient programmed cell death regulator - the crystal structure of marine sponge BHP2 bound to LB-Bak-2.
1. Cell Death Dis - published January 12, 2017
2. Caria S, Hinds MG, Kvansakul M
Division of labor among Mycobacterium smegmatis RNase H enzymes: RNase H1 activity of RnhA or RnhC is essential for growth whereas RnhB and RnhA guard against killing by hydrogen peroxide in stationary phase.
1. Nucleic Acids Res - published January 9, 2017
2. Gupta R, Chatterjee D, Glickman MS, Shuman S
Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA.
1. Elife - published January 9, 2017
2. Hubin EA, Fay A, Xu C, Bean JM, Saecker RM, Glickman MS, Darst SA, Campbell EA
Visualizing the secondary and tertiary architectural domains of lncRNA RepA.
1. Nat Chem Biol - published January 9, 2017
2. Liu F, Somarowthu S, Pyle AM
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de-differentiated state.
1. Mol Syst Biol - published January 9, 2017
2. Fallahi-Sichani M, Becker V, Izar B, Baker GJ, Lin JR, Boswell SA, Shah P, Rotem A, Garraway LA, Sorger PK
A Novel Phosphodiesterase of the GdpP Family Modulates Cyclic di-AMP Levels in Response to Cell Membrane Stress in Daptomycin-Resistant Enterococci.
1. Antimicrob Agents Chemother - published January 9, 2017
2. Wang X, Davlieva M, Reyes J, Panesso D, Arias CA, Shamoo Y
Possible physiological role for bi-directional motility and motor clustering of the mitotic kinesin-5 Cin8.
1. J Cell Sci - published January 9, 2017
2. Shapira O, Goldstein A, Al-Bassam J, Gheber L
Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP.
1. Proc Natl Acad Sci U S A - published January 9, 2017
2. Nöll A, Thomas C, Herbring V, Zollmann T, Barth K, Mehdipour AR, Tomasiak TM, Brüchert S, Joseph B, Abele R, Oliéric V, Wang M, Diederichs K, Hummer G, Stroud RM, Pos KM, Tampé R
Rescue of Hearing by Gene Delivery to Inner-Ear Hair Cells Using Exosome-Associated AAV.
1. Mol Ther - published January 9, 2017
2. György B, Sage C, Indzhykulian AA, Scheffer DI, Brisson AR, Tan S, Wu X, Volak A, Mu D, Tamvakologos PI, Li Y, Fitzpatrick Z, Ericsson M, Breakefield XO, Corey DP, Maguire CA
Preface.
1. Methods Enzymol - published January 8, 2017
2. Spies M, Chemla YR
Have NEC Coat, Will Travel: Structural Basis of Membrane Budding During Nuclear Egress in Herpesviruses.
1. Adv Virus Res - published January 7, 2017
2. Bigalke JM, Heldwein EE
Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family.
1. Nat Commun - published January 6, 2017
2. Ehrnstorfer IA, Manatschal C, Arnold FM, Laederach J, Dutzler R
Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1.
1. Elife - published January 6, 2017
2. Ren Y, Schmiege P, Blobel G
Histone chaperone networks shaping chromatin function.
1. Nat Rev Mol Cell Biol - published January 5, 2017
2. Hammond CM, Strømme CB, Huang H, Patel DJ, Groth A
Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting.
1. PLoS Pathog - published January 4, 2017
2. Doria-Rose NA, Altae-Tran HR, Roark RS, Schmidt SD, Sutton MS, Louder MK, Chuang GY, Bailer RT, Cortez V, Kong R, McKee K, O'Dell S, Wang F, Abdool Karim SS, Binley JM, Connors M, Haynes BF, Martin MA, Montefiori DC, Morris L, Overbaugh J, Kwong PD, Mascola JR, Georgiev IS
Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators.
1. Proc Natl Acad Sci U S A - published January 3, 2017
2. Flitter BA, Hvorecny KL, Ono E, Eddens T, Yang J, Kwak DH, Bahl CD, Hampton TH, Morisseau C, Hammock BD, Liu X, Lee JS, Kolls JK, Levy BD, Madden DR, Bomberger JM
An allosteric conduit facilitates dynamic multisite substrate recognition by the SCFCdc4 ubiquitin ligase.
1. Nat Commun - published January 3, 2017
2. Csizmok V, Orlicky S, Cheng J, Song J, Bah A, Delgoshaie N, Lin H, Mittag T, Sicheri F, Chan HS, Tyers M, Forman-Kay JD
Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity.
1. Elife - published January 3, 2017
2. Krotee P, Rodriguez JA, Sawaya MR, Cascio D, Reyes FE, Shi D, Hattne J, Nannenga BL, Oskarsson ME, Philipp S, Griner S, Jiang L, Glabe CG, Westermark GT, Gonen T, Eisenberg DS
Crystallogenesis of Membrane Proteins Mediated by Polymer-Bounded Lipid Nanodiscs.
1. Structure - published January 3, 2017
2. Broecker J, Eger BT, Ernst OP
A novel pre-fusion conformation-specific neutralizing epitope on the respiratory syncytial virus fusion protein.
1. Nat Microbiol - published January 3, 2017
2. Mousa JJ, Kose N, Matta P, Gilchuk P, Crowe JE Jr
Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus.
1. Nat Microbiol - published January 3, 2017
2. Wen X, Mousa JJ, Bates JT, Lamb RA, Crowe JE Jr, Jardetzky TS
Structural basis for ELL2 and AFF4 activation of HIV-1 proviral transcription.
1. Nat Commun - published January 3, 2017
2. Qi S, Li Z, Schulze-Gahmen U, Stjepanovic G, Zhou Q, Hurley JH
Chromatin potentiates transcription.
1. Proc Natl Acad Sci U S A - published January 3, 2017
2. Nagai S, Davis RE, Mattei PJ, Eagen KP, Kornberg RD
Conformational change of syntaxin linker region induced by Munc13s initiates SNARE complex formation in synaptic exocytosis.
1. EMBO J - published January 3, 2017
2. Wang S, Choi UB, Gong J, Yang X, Li Y, Wang AL, Yang X, Brunger AT, Ma C
The Type IVa Pilus Machinery Is Recruited to Sites of Future Cell Division.
1. MBio - published January 3, 2017
2. Carter T, Buensuceso RN, Tammam S, Lamers RP, Harvey H, Howell PL, Burrows LL
Homologous recombination mediated by the mycobacterial AdnAB helicase without end resection by the AdnAB nucleases.
1. Nucleic Acids Res - published January 2, 2017
2. Gupta R, Unciuleac MC, Shuman S, Glickman MS
Internal Structure and Preferential Protein Binding of Colloidal Aggregates.
1. ACS Chem Biol - published January 2, 2017
2. Duan D, Torosyan H, Elnatan D, McLaughlin CK, Logie J, Shoichet MS, Agard DA, Shoichet BK
SIRT7 Is an RNA-Activated Protein Lysine Deacylase.
1. ACS Chem Biol - published January 2, 2017
2. Tong Z, Wang M, Wang Y, Kim DD, Grenier JK, Cao J, Sadhukhan S, Hao Q, Lin H
Watching real-time endocytosis in living cells.
1. J Cell Biol - published January 2, 2017
2. Frazier MN, Jackson LP
Rapid PD-L1 detection in tumors with PET using a highly specific peptide.
1. Biochem Biophys Res Commun - published January 2, 2017
2. Chatterjee S, Lesniak WG, Miller MS, Lisok A, Sikorska E, Wharram B, Kumar D, Gabrielson M, Pomper MG, Gabelli SB, Nimmagadda S
Ligand Discovery for a Peptide-Binding GPCR by Structure-Based Screening of Fragment- and Lead-Like Chemical Libraries.
1. ACS Chem Biol - published January 2, 2017
2. Ranganathan A, Heine P, Rudling A, Plückthun A, Kummer L, Carlsson J
Reversible covalent interactions of β-aminoboronic acids with carbohydrate derivatives.
1. Chem Commun (Camb) - published January 2, 2017
2. Garrett GE, Diaz DB, Yudin AK, Taylor MS
Distortion of histone octamer core promotes nucleosome mobilization by a chromatin remodeler.
1. Science - published January 2, 2017
2. Sinha KK, Gross JD, Narlikar GJ
The role of dimer asymmetry and protomer dynamics in enzyme catalysis.
1. Science - published January 2, 2017
2. Kim TH, Mehrabi P, Ren Z, Sljoka A, Ing C, Bezginov A, Ye L, Pomès R, Prosser RS, Pai EF
The transcription factor musculin promotes the unidirectional development of peripheral Treg cells by suppressing the TH2 transcriptional program.
1. Nat Immunol - published January 2, 2017
2. Wu C, Chen Z, Dardalhon V, Xiao S, Thalhamer T, Liao M, Madi A, Franca RF, Han T, Oukka M, Kuchroo V
A tale of two glutaminases: homologous enzymes with distinct roles in tumorigenesis.
1. Future Med Chem - published January 2, 2017
2. Katt WP, Lukey MJ, Cerione RA
Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases.
1. Cell - published January 2, 2017
2. Guo CJ, Chang FY, Wyche TP, Backus KM, Acker TM, Funabashi M, Taketani M, Donia MS, Nayfach S, Pollard KS, Craik CS, Cravatt BF, Clardy J, Voigt CA, Fischbach MA
Structure of the active form of human Origin Recognition Complex and its ATPase motor module.
1. Elife - published January 2, 2017
2. Tocilj A, On KF, Yuan Z, Sun J, Elkayam E, Li H, Stillman B, Joshua-Tor L
Sec3 promotes the initial binary t-SNARE complex assembly and membrane fusion.
1. Nat Commun - published January 2, 2017
2. Yue P, Zhang Y, Mei K, Wang S, Lesigang J, Zhu Y, Dong G, Guo W
RNA and DNA Targeting by a Reconstituted Thermus thermophiles Type III-A CRISPR-Cas System.
1. PLoS One - published January 2, 2017
2. Liu TY, Iavarone AT, Doudna JA
Structural insights into RNA synthesis by the influenza virus transcription-replication machine.
1. Virus Res - published January 2, 2017
2. Pflug A, Lukarska M, Resa-Infante P, Reich S, Cusack S
Force interacts with macromolecular structure in activation of TGF-β.
1. Nature - published January 2, 2017
2. Dong X, Zhao B, Iacob RE, Zhu J, Koksal AC, Lu C, Engen JR, Springer TA
Mechanism of catalysis, E2 recognition, and autoinhibition for the IpaH family of bacterial E3 ubiquitin ligases.
1. Proc Natl Acad Sci U S A - published January 2, 2017
2. Keszei AF, Sicheri F
Genetic Drivers of Kidney Defects in the DiGeorge Syndrome.
1. N Engl J Med - published January 2, 2017
2. Lopez-Rivera E, Liu YP, Verbitsky M, Anderson BR, Capone VP, Otto EA, Yan Z, Mitrotti A, Martino J, Steers NJ, Fasel DA, Vukojevic K, Deng R, Racedo SE, Liu Q, Werth M, Westland R, Vivante A, Makar GS, Bodria M, Sampson MG, Gillies CE, Vega-Warner V, Maiorana M, Petrey DS, Honig B, Lozanovski VJ, Salomon R, Heidet L, Carpentier W, Gaillard D, Carrea A, Gesualdo L, Cusi D, Izzi C, Scolari F, van Wijk JA, Arapovic A, Saraga-Babic M, Saraga M, Kunac N, Samii A, McDonald-McGinn DM, Crowley TB, Zackai EH, Drozdz D, Miklaszewska M, Tkaczyk M, Sikora P, Szczepanska M, Mizerska-Wasiak M, Krzemien G, Szmigielska A, Zaniew M, Darlow JM, Puri P, Barton D, Casolari E, Furth SL, Warady BA, Gucev Z, Hakonarson H, Flogelova H, Tasic V, Latos-Bielenska A, Materna-Kiryluk A, Allegri L, Wong CS, Drummond IA, D'Agati V, Imamoto A, Barasch JM, Hildebrandt F, Kiryluk K, Lifton RP, Morrow BE, Jeanpierre C, Papaioannou VE, Ghiggeri GM, Gharavi AG, Katsanis N, Sanna-Cherchi S
sNASP and ASF1A function through both competitive and compatible modes of histone binding.
1. Nucleic Acids Res - published January 2, 2017
2. Bowman A, Koide A, Goodman JS, Colling ME, Zinne D, Koide S, Ladurner AG
Conformational equilibria and intrinsic affinities define integrin activation.
1. EMBO J - published January 2, 2017
2. Li J, Su Y, Xia W, Qin Y, Humphries MJ, Vestweber D, Cabañas C, Lu C, Springer TA
The Vps13p-Cdc31p complex is directly required for TGN late endosome transport and TGN homotypic fusion.
1. J Cell Biol - published January 2, 2017
2. De M, Oleskie AN, Ayyash M, Dutta S, Mancour L, Abazeed ME, Brace EJ, Skiniotis G, Fuller RS
Sorting zebrafish thrombocyte lineage cells with a Cd41 monoclonal antibody enriches hematopoietic stem cell activity.
1. Blood - published January 2, 2017
2. Gansner JM, Leung AD, Superdock M, Blair MC, Ammerman MB, Durand EM, Barut B, Handin RI, Stachura DL, Lu C, Springer TA, Zon LI
CD244 maintains the proliferation ability of leukemia initiating cells through SHP-2/p27kip1 signaling.
1. Haematologica - published January 2, 2017
2. Zhang F, Liu X, Chen C, Zhu J, Yu Z, Xie J, Xie L, Bai H, Zhang Y, Fang X, Gu H, Wang C, Weng W, Zhang CC, Chen GQ, Liang A, Zheng J
An in vitro fluorescence based study of initiation of RNA synthesis by influenza B polymerase.
1. Nucleic Acids Res - published January 2, 2017
2. Reich S, Guilligay D, Cusack S
Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library.
1. Proc Natl Acad Sci U S A - published January 2, 2017
2. Ahn S, Kahsai AW, Pani B, Wang QT, Zhao S, Wall AL, Strachan RT, Staus DP, Wingler LM, Sun LD, Sinnaeve J, Choi M, Cho T, Xu TT, Hansen GM, Burnett MB, Lamerdin JE, Bassoni DL, Gavino BJ, Husemoen G, Olsen EK, Franch T, Costanzi S, Chen X, Lefkowitz RJ
A novel human CAMK2A mutation disrupts dendritic morphology and synaptic transmission, and causes ASD-related behaviors.
1. J Neurosci - published January 2, 2017
2. Stephenson JR, Wang X, Perfitt TL, Parrish WP, Shonesy BC, Marks CR, Mortlock DP, Nakagawa T, Sutcliffe JS, Colbran RJ
Thiazolidine reacts with thioreactive biomolecules.
1. Free Radic Biol Med - published January 2, 2017
2. Su D, Nian Y, Zhang F, Hu J, Cui J, Zhou M, Yang J, Wang S
A structural view of the RNA-dependent RNA polymerases from the Flavivirus genus.
1. Virus Res - published January 2, 2017
2. Lu G, Gong P
Clr4 specificity and catalytic activity beyond H3K9 methylation.
1. Biochimie - published January 2, 2017
2. Kusevic D, Kudithipudi S, Iglesias N, Moazed D, Jeltsch A
Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via Wnt Signaling and Stabilization of Low Density Lipoprotein Receptor-related Proteins 5 and 6.
1. Gastroenterology - published January 2, 2017
2. Lai KK, Kweon SM, Chi F, Hwang E, Kabe Y, Higashiyama R, Qin L, Yan R, Wu RP, Fujii N, French S, Xu J, Wang JY, Murali R, Mishra L, Lee JS, Ntambi JM, Tsukamoto H
Calcium-NFAT transcriptional signalling in T cell activation and T cell exhaustion.
1. Cell Calcium - published January 2, 2017
2. Hogan PG
Starvation and recovery in the deep-sea methanotroph Methyloprofundus sedimenti.
1. Mol Microbiol - published January 1, 2017
2. Tavormina PL, Kellermann MY, Antony CP, Tocheva EI, Dalleska NF, Jensen AJ, Valentine DL, Hinrichs KU, Jensen GJ, Dubilier N, Orphan VJ
Identification of G-quadruplexes in long functional RNAs using 7-deazaguanine RNA.
1. Nat Chem Biol - published January 1, 2017
2. Weldon C, Behm-Ansmant I, Hurley LH, Burley GA, Branlant C, Eperon IC, Dominguez C
Multidimensional chemical control of CRISPR-Cas9.
1. Nat Chem Biol - published January 1, 2017
2. Maji B, Moore CL, Zetsche B, Volz SE, Zhang F, Shoulders MD, Choudhary A
Phospholipid regulation of the nuclear receptor superfamily.
1. Adv Biol Regul - published January 1, 2017
2. Crowder MK, Seacrist CD, Blind RD
Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
1. J Biol Chem - published January 1, 2017
2. Esser L, Zhou F, Pluchino KM, Shiloach J, Ma J, Tang WK, Gutierrez C, Zhang A, Shukla S, Madigan JP, Zhou T, Kwong PD, Ambudkar SV, Gottesman MM, Xia D
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.
1. Nat Genet - published January 1, 2017
2. Marshall CR, Howrigan DP, Merico D, Thiruvahindrapuram B, Wu W, Greer DS, Antaki D, Shetty A, Holmans PA, Pinto D, Gujral M, Brandler WM, Malhotra D, Wang Z, Fajarado KVF, Maile MS, Ripke S, Agartz I, Albus M, Alexander M, Amin F, Atkins J, Bacanu SA, Belliveau RA Jr, Bergen SE, Bertalan M, Bevilacqua E, Bigdeli TB, Black DW, Bruggeman R, Buccola NG, Buckner RL, Bulik-Sullivan B, Byerley W, Cahn W, Cai G, Cairns MJ, Campion D, Cantor RM, Carr VJ, Carrera N, Catts SV, Chambert KD, Cheng W, Cloninger CR, Cohen D, Cormican P, Craddock N, Crespo-Facorro B, Crowley JJ, Curtis D, Davidson M, Davis KL, Degenhardt F, Del Favero J, DeLisi LE, Dikeos D, Dinan T, Djurovic S, Donohoe G, Drapeau E, Duan J, Dudbridge F, Eichhammer P, Eriksson J, Escott-Price V, Essioux L, Fanous AH, Farh KH, Farrell MS, Frank J, Franke L, Freedman R, Freimer NB, Friedman JI, Forstner AJ, Fromer M, Genovese G, Georgieva L, Gershon ES, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, Gratten J, de Haan L, Hamshere ML, Hansen M, Hansen T, Haroutunian V, Hartmann AM, Henskens FA, Herms S, Hirschhorn JN, Hoffmann P, Hofman A, Huang H, Ikeda M, Joa I, Kähler AK, Kahn RS, Kalaydjieva L, Karjalainen J, Kavanagh D, Keller MC, Kelly BJ, Kennedy JL, Kim Y, Knowles JA, Konte B, Laurent C, Lee P, Lee SH, Legge SE, Lerer B, Levy DL, Liang KY, Lieberman J, Lönnqvist J, Loughland CM, Magnusson PKE, Maher BS, Maier W, Mallet J, Mattheisen M, Mattingsdal M, McCarley RW, McDonald C, McIntosh AM, Meier S, Meijer CJ, Melle I, Mesholam-Gately RI, Metspalu A, Michie PT, Milani L, Milanova V, Mokrab Y, Morris DW, Müller-Myhsok B, Murphy KC, Murray RM, Myin-Germeys I, Nenadic I, Nertney DA, Nestadt G, Nicodemus KK, Nisenbaum L, Nordin A, O'Callaghan E, O'Dushlaine C, Oh SY, Olincy A, Olsen L, O'Neill FA, Van Os J, Pantelis C, Papadimitriou GN, Parkhomenko E, Pato MT, Paunio T, Psychosis Endophenotypes International Consortium., Perkins DO, Pers TH, Pietiläinen O, Pimm J, Pocklington AJ, Powell J, Price A, Pulver AE, Purcell SM, Quested D, Rasmussen HB, Reichenberg A, Reimers MA, Richards AL, Roffman JL, Roussos P, Ruderfer DM, Salomaa V, Sanders AR, Savitz A, Schall U, Schulze TG, Schwab SG, Scolnick EM, Scott RJ, Seidman LJ, Shi J, Silverman JM, Smoller JW, Söderman E, Spencer CCA, Stahl EA, Strengman E, Strohmaier J, Stroup TS, Suvisaari J, Svrakic DM, Szatkiewicz JP, Thirumalai S, Tooney PA, Veijola J, Visscher PM, Waddington J, Walsh D, Webb BT, Weiser M, Wildenauer DB, Williams NM, Williams S, Witt SH, Wolen AR, Wormley BK, Wray NR, Wu JQ, Zai CC, Adolfsson R, Andreassen OA, Blackwood DHR, Bramon E, Buxbaum JD, Cichon S, Collier DA, Corvin A, Daly MJ, Darvasi A, Domenici E, Esko T, Gejman PV, Gill M, Gurling H, Hultman CM, Iwata N, Jablensky AV, Jönsson EG, Kendler KS, Kirov G, Knight J, Levinson DF, Li QS, McCarroll SA, McQuillin A, Moran JL, Mowry BJ, Nöthen MM, Ophoff RA, Owen MJ, Palotie A, Pato CN, Petryshen TL, Posthuma D, Rietschel M, Riley BP, Rujescu D, Sklar P, St Clair D, Walters JTR, Werge T, Sullivan PF, O'Donovan MC, Scherer SW, Neale BM, Sebat J, CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium.
Inactivation of urease by catechol: Kinetics and structure.
1. J Inorg Biochem - published January 1, 2017
2. Mazzei L, Cianci M, Musiani F, Lente G, Palombo M, Ciurli S
Coupling immunity and programmed cell suicide in prokaryotes: Life-or-death choices.
1. Bioessays - published January 1, 2017
2. Koonin EV, Zhang F
Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array.
1. Nat Biotechnol - published January 1, 2017
2. Zetsche B, Heidenreich M, Mohanraju P, Fedorova I, Kneppers J, DeGennaro EM, Winblad N, Choudhury SR, Abudayyeh OO, Gootenberg JS, Wu WY, Scott DA, Severinov K, van der Oost J, Zhang F
Structural dynamics and DNA interaction of human TFIID.
1. Transcription - published January 1, 2017
2. Nogales E, Fang J, Louder RK
Molecular biology: Messenger RNAs marked for longer life.
1. Nature - published January 1, 2017
2. Weinberg DE, Gross JD
Human Mitochondrial Ferredoxin 1 (FDX1) and Ferredoxin 2 (FDX2) Both Bind Cysteine Desulfurase and Donate Electrons for Iron-Sulfur Cluster Biosynthesis.
1. Biochemistry - published January 1, 2017
2. Cai K, Tonelli M, Frederick RO, Markley JL
Genetic differences in osteogenic differentiation potency in the thoracic ossification of the ligamentum flavum under cyclic mechanical stress.
1. Int J Mol Med - published January 1, 2017
2. Ning S, Chen Z, Fan D, Sun C, Zhang C, Zeng Y, Li W, Hou X, Qu X, Ma Y, Yu H
A snapshot of cryo-EM.
1. Protein Sci - published January 1, 2017
2. Skiniotis G
Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core.
1. Acta Crystallogr D Struct Biol - published January 1, 2017
2. Montemayor EJ, Didychuk AL, Liao H, Hu P, Brow DA, Butcher SE
Guard the guardian: A CRL4 ligase stands watch over histone production.
1. Nucleus - published January 1, 2017
2. Lampert F, Brodersen MM, Peter M
A sequential multi-target Mps1 phosphorylation cascade promotes spindle checkpoint signaling.
1. Elife - published January 1, 2017
2. Ji Z, Gao H, Jia L, Li B, Yu H
Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.
1. PLoS Pathog - published January 1, 2017
2. Wibmer CK, Gorman J, Ozorowski G, Bhiman JN, Sheward DJ, Elliott DH, Rouelle J, Smira A, Joyce MG, Ndabambi N, Druz A, Asokan M, Burton DR, Connors M, Abdool Karim SS, Mascola JR, Robinson JE, Ward AB, Williamson C, Kwong PD, Morris L, Moore PL
PLA2G16 represents a switch between entry and clearance of Picornaviridae.
1. Nature - published January 1, 2017
2. Staring J, von Castelmur E, Blomen VA, van den Hengel LG, Brockmann M, Baggen J, Thibaut HJ, Nieuwenhuis J, Janssen H, van Kuppeveld FJ, Perrakis A, Carette JE, Brummelkamp TR
Neutralization of Diverse Human Cytomegalovirus Strains Conferred by Antibodies Targets Viral gH/gL/pUL128-131 Pentameric Complex.
1. J Virol - published January 1, 2017
2. Ha S, Li F, Troutman MC, Freed DC, Tang A, Loughney JW, Wang D, Wang IM, Vlasak J, Nickle DC, Rustandi RR, Hamm M, DePhillips PA, Zhang N, McLellan JS, Zhu H, Adler SP, McVoy MA, An Z, Fu TM
Is CD47 an innate immune checkpoint for tumor evasion?
1. J Hematol Oncol - published January 1, 2017
2. Liu X, Kwon H, Li Z, Fu YX
The cif Virulence Factor Gene Is Present in Isolates From Patients With Pseudomonas aeruginosa Keratitis.
1. Cornea - published January 1, 2017
2. Bahl CD, St Laurent JD, Karthikeyan RS, Priya JL, Prajna L, Zegans ME, Madden DR
The large terminase DNA packaging motor grips DNA with its ATPase domain for cleavage by the flexible nuclease domain.
1. Nucleic Acids Res - published January 1, 2017
2. Hilbert BJ, Hayes JA, Stone NP, Xu RG, Kelch BA
Structures of the Human HCN1 Hyperpolarization-Activated Channel.
1. Cell - published January 1, 2017
2. Lee CH, MacKinnon R
Getting to and through the inner nuclear membrane during herpesvirus nuclear egress.
1. Curr Opin Cell Biol - published January 1, 2017
2. Lye MF, Wilkie AR, Filman DJ, Hogle JM, Coen DM
SnapShot: Class 2 CRISPR-Cas Systems.
1. Cell - published January 1, 2017
2. Makarova KS, Zhang F, Koonin EV
p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma.
1. Blood - published January 1, 2017
2. Hideshima T, Cottini F, Nozawa Y, Seo HS, Ohguchi H, Samur MK, Cirstea D, Mimura N, Iwasawa Y, Richardson PG, Munshi NC, Chauhan D, Massefski W, Utsugi T, Dhe-Paganon S, Anderson KC
Assembly of a nucleus-like structure during viral replication in bacteria.
1. Science - published January 1, 2017
2. Chaikeeratisak V, Nguyen K, Khanna K, Brilot AF, Erb ML, Coker JK, Vavilina A, Newton GL, Buschauer R, Pogliano K, Villa E, Agard DA, Pogliano J
Molecular Mechanisms of Autophagy-Part B.
1. J Mol Biol - published January 1, 2017
2. Tooze SA, Hurley JH
Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis.
1. Nat Chem Biol - published January 1, 2017
2. Rodrigues MJ, Windeisen V, Zhang Y, Guédez G, Weber S, Strohmeier M, Hanes JW, Royant A, Evans G, Sinning I, Ealick SE, Begley TP, Tews I
Antibody 10-1074 suppresses viremia in HIV-1-infected individuals.
1. Nat Med - published January 1, 2017
2. Caskey M, Schoofs T, Gruell H, Settler A, Karagounis T, Kreider EF, Murrell B, Pfeifer N, Nogueira L, Oliveira TY, Learn GH, Cohen YZ, Lehmann C, Gillor D, Shimeliovich I, Unson-O'Brien C, Weiland D, Robles A, Kümmerle T, Wyen C, Levin R, Witmer-Pack M, Eren K, Ignacio C, Kiss S, West AP Jr, Mouquet H, Zingman BS, Gulick RM, Keler T, Bjorkman PJ, Seaman MS, Hahn BH, Fätkenheuer G, Schlesinger SJ, Nussenzweig MC, Klein F
Molecular architecture and dynamics of ASH1 mRNA recognition by its mRNA-transport complex.
1. Nat Struct Mol Biol - published January 1, 2017
2. Edelmann FT, Schlundt A, Heym RG, Jenner A, Niedner-Boblenz A, Syed MI, Paillart JC, Stehle R, Janowski R, Sattler M, Jansen RP, Niessing D
Mechanisms and regulation of DNA replication initiation in eukaryotes.
1. Crit Rev Biochem Mol Biol - published January 1, 2017
2. Parker MW, Botchan MR, Berger JM
Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach.
1. PLoS Med - published January 1, 2017
2. Mendelson MM, Marioni RE, Joehanes R, Liu C, Hedman ÅK, Aslibekyan S, Demerath EW, Guan W, Zhi D, Yao C, Huan T, Willinger C, Chen B, Courchesne P, Multhaup M, Irvin MR, Cohain A, Schadt EE, Grove ML, Bressler J, North K, Sundström J, Gustafsson S, Shah S, McRae AF, Harris SE, Gibson J, Redmond P, Corley J, Murphy L, Starr JM, Kleinbrink E, Lipovich L, Visscher PM, Wray NR, Krauss RM, Fallin D, Feinberg A, Absher DM, Fornage M, Pankow JS, Lind L, Fox C, Ingelsson E, Arnett DK, Boerwinkle E, Liang L, Levy D, Deary IJ
Characterization of the dTDP-Fuc3N and dTDP-Qui3N biosynthetic pathways in Campylobacter jejuni 81116†.
1. Glycobiology - published January 1, 2017
2. Li ZZ, Riegert AS, Goneau MF, Cunningham AM, Vinogradov E, Li J, Schoenhofen IC, Thoden JB, Holden HM, Gilbert M
Tuning the ion selectivity of two-pore channels.
1. Proc Natl Acad Sci U S A - published January 1, 2017
2. Guo J, Zeng W, Jiang Y
Quantifying Kinetics from Time Series of Single-Molecule FRET Efficiency Histograms.
1. Nanotechnology - published January 1, 2017
2. Benke S, Nettels D, Hofmann H, Schuler B
Erratum: A unified molecular mechanism for the regulation of acetyl-CoA carboxylase by phosphorylation.
1. Cell Discov - published January 1, 2017
2. Wei J, Zhang Y, Yu TY, Sadre-Bazzaz K, Rudolph MJ, Amodeo GA, Symington LS, Walz T, Tong L
Influence of the Envelope Gp120 Phe 43 Cavity on HIV-1 Sensitivity to ADCC Responses.
1. J Virol - published January 1, 2017
2. Prévost J, Zoubchenok D, Richard J, Veillette M, Pacheco B, Coutu M, Brassard N, Parsons MS, Ruxrungtham K, Bunupuradah T, Tovanabutra S, Hwang KK, Moody MA, Haynes BF, Bonsignori M, Sodroski J, Kaufmann DE, Shaw GM, Chenine AL, Finzi A
Cool-associated tyrosine phosphorylated protein-1 is required for the anchorage-independent growth of cervical carcinoma cells by binding paxillin and promoting AKT activation.
1. J Biol Chem - published January 1, 2017
2. Yoo SM, Latifkar A, Cerione RA, Antonyak MA
Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
1. Sci Transl Med - published January 1, 2017
2. Freund NT, Wang H, Scharf L, Nogueira L, Horwitz JA, Bar-On Y, Golijanin J, Sievers SA, Sok D, Cai H, Cesar Lorenzi JC, Halper-Stromberg A, Toth I, Piechocka-Trocha A, Gristick HB, van Gils MJ, Sanders RW, Wang LX, Seaman MS, Burton DR, Gazumyan A, Walker BD, West AP Jr, Bjorkman PJ, Nussenzweig MC
Guanine can direct binding specificity of Ru-dppz complexes to DNA through steric effects.
1. Chemistry - published January 1, 2017
2. Hall JP, Gurung SP, Henle J, Poidl P, Andersson J, Lincoln P, Winter G, Sorensen T, Cardin DJ, Brazier JA, Cardin CJ
Extracellular Vesicle Docking at the Cellular Port: Extracellular Vesicle Binding and Uptake.
1. Semin Cell Dev Biol - published January 1, 2017
2. French KC, Antonyak MA, Cerione RA
Interdomain Communication of the Chd1 Chromatin Remodeler across the DNA Gyres of the Nucleosome.
1. Mol Cell - published January 1, 2017
2. Nodelman IM, Bleichert F, Patel A, Ren R, Horvath KC, Berger JM, Bowman GD
The Trypanosome Exocyst: A Conserved Structure Revealing a New Role in Endocytosis.
1. PLoS Pathog - published January 1, 2017
2. Boehm CM, Obado S, Gadelha C, Kaupisch A, Manna PT, Gould GW, Munson M, Chait BT, Rout MP, Field MC
Structural Titration of Slo2.2, a Na+-Dependent K+ Channel.
1. Cell - published January 1, 2017
2. Hite RK, MacKinnon R
Defining Uniform Processes for Remediation, Probation and Termination in Residency Training.
1. West J Emerg Med - published January 1, 2017
2. Smith JL, Lypson M, Silverberg M, Weizberg M, Murano T, Lukela M, Santen SA
Targeted CRISPR disruption reveals a role for RNase MRP RNA in human preribosomal RNA processing.
1. Genes Dev - published January 1, 2017
2. Goldfarb KC, Cech TR
Antibodyomics: bioinformatics technologies for understanding B-cell immunity to HIV-1.
1. Immunol Rev - published January 1, 2017
2. Kwong PD, Chuang GY, DeKosky BJ, Gindin T, Georgiev IS, Lemmin T, Schramm CA, Sheng Z, Soto C, Yang AS, Mascola JR, Shapiro L
Mutation profiles in early-stage lung squamous cell carcinoma with clinical follow-up and correlation with markers of immune function.
1. Ann Oncol - published January 1, 2017
2. Choi M, Kadara H, Zhang J, Parra ER, Rodriguez-Canales J, Gaffney SG, Zhao Z, Behrens C, Fujimoto J, Chow C, Kim K, Kalhor N, Moran C, Rimm D, Swisher S, Gibbons DL, Heymach J, Kaftan E, Townsend JP, Lynch TJ, Schlessinger J, Lee J, Lifton RP, Herbst RS, Wistuba II
Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors.
1. Genes Dev - published January 1, 2017
2. Zinder JC, Lima CD
One size doesn't fit all: unraveling the diversity of factors and interactions that drive E. coli urovirulence.
1. Ann Transl Med - published January 1, 2017
2. Schreiber HL 4th, Spaulding CN, Dodson KW, Livny J, Hultgren SJ
Chromatin-remodeling for transcription.
1. Q Rev Biophys - published January 1, 2017
2. Lorch Y, Kornberg RD