Member Publications

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94 Member Publications for January 2015

Effect of Lipid Head Groups on Double-Layered Two-Dimensional Crystals Formed by Aquaporin-0.
1. PLoS ONE - published January 31, 2015
2. Hite RK, Chiu PL, Schuller JM, Walz T
Structure-Guided Design of a High Affinity Inhibitor to Human CtBP.
1. ACS Chem. Biol. - published January 30, 2015
2. Hilbert BJ, Morris BL, Ellis KC, Paulsen JL, Schiffer CA, Grossman SR, Royer WE
Facile synthesis of borofragments and their evaluation in activity-based protein profiling.
1. Chem. Commun. (Camb.) - published January 30, 2015
2. Adachi S, Cognetta AB, Niphakis MJ, He Z, Zajdlik A, St Denis JD, Scully CC, Cravatt BF, Yudin AK
Differential Stabilities and Sequence-Dependent Base Pair Opening Dynamics of Watson-Crick Base Pairs with 5-Hydroxymethylcytosine, 5-Formylcytosine, or 5-Carboxylcytosine.
1. Biochemistry - published January 29, 2015
2. Szulik MW, Pallan PS, Nocek B, Voehler M, Banerjee S, Brooks S, Joachimiak A, Egli M, Eichman BF, Stone MP
Angiomotin functions in HIV-1 assembly and budding.
1. Elife - published January 29, 2015
2. Mercenne G, Alam SL, Arii J, Lalonde MS, Sundquist WI
Intra-Spike Crosslinking Overcomes Antibody Evasion by HIV-1.
1. Cell - published January 29, 2015
2. Galimidi RP, Klein JS, Politzer MS, Bai S, Seaman MS, Nussenzweig MC, West AP, Bjorkman PJ
NECTIN-LIKE INTERACTIONS BETWEEN POLIOVIRUS AND ITS RECEPTOR TRIGGER CONFORMATIONAL CHANGES ASSOCIATED WITH CELL ENTRY.
1. J. Virol. - published January 28, 2015
2. Strauss M, Filman DJ, Belnap DM, Cheng N, Noel RT, Hogle JM
Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors.
1. Eur J Med Chem - published January 27, 2015
2. Li R, Cheng C, Balasis ME, Liu Y, Garner TP, Daniel KG, Li J, Qin Y, Gavathiotis E, Sebti SM
Synthesis of 2'-O-photocaged ribonucleoside phosphoramidites.
1. Nucleosides Nucleotides Nucleic Acids - published January 27, 2015
2. Lu J, Koo SC, Li NS, Piccirilli JA
Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway.
1. Sci Rep - published January 27, 2015
2. Fraga J, Maranha A, Mendes V, Pereira PJ, Empadinhas N, Macedo-Ribeiro S
A Structural Perspective on the Regulation of the Epidermal Growth Factor Receptor.
1. Annu. Rev. Biochem. - published January 26, 2015
2. Kovacs E, Zorn JA, Huang Y, Barros T, Kuriyan J
Structural and biochemical studies of HCMV gH/gL/gO and Pentamer reveal mutually exclusive cell entry complexes.
1. Proc. Natl. Acad. Sci. U.S.A. - published January 26, 2015
2. Ciferri C, Chandramouli S, Donnarumma D, Nikitin PA, Cianfrocco MA, Gerrein R, Feire AL, Barnett SW, Lilja AE, Rappuoli R, Norais N, Settembre EC, Carfi A
Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices.
1. Proc. Natl. Acad. Sci. U.S.A. - published January 26, 2015
2. Leshchiner ES, Parkhitko A, Bird GH, Luccarelli J, Bellairs JA, Escudero S, Opoku-Nsiah K, Godes M, Perrimon N, Walensky LD
Macrocyclic templates for library synthesis of peptido-conjugates.
1. Methods Mol Biol - published January 25, 2015
2. Zaretsky S, Tan J, Hickey JL, Yudin AK
PD-L1(hi) B cells are critical regulators of humoral immunity.
1. Nat Commun - published January 23, 2015
2. Khan AR, Hams E, Floudas A, Sparwasser T, Weaver CT, Fallon PG
PscI is a type III secretion needle anchoring protein with in vitro polymerization capacities.
1. Mol. Microbiol. - published January 23, 2015
2. Monlezun L, Liebl D, Fenel D, Grandjean T, Berry A, Schoehn G, Dessein R, Faudry E, Attree I
Heparin is an activating ligand of the orphan receptor tyrosine kinase ALK.
1. Sci Signal - published January 22, 2015
2. Murray PB, Lax I, Reshetnyak A, Ligon GF, Lillquist JS, Natoli EJ, Shi X, Folta-Stogniew E, Gunel M, Alvarado D, Schlessinger J
Mapping Conformational Heterogeneity of Mitochondrial Nucleotide Transporter in Uninhibited States.
1. Angew. Chem. Int. Ed. Engl. - published January 21, 2015
2. Sounier R, Bellot G, Chou JJ
Dimerization and phosphatase activity of calcyclin-binding protein/Siah-1 interacting protein: the influence of oxidative stress.
1. FASEB J. - published January 21, 2015
2. Topolska-Woś AM, Shell SM, Kilańczyk E, Szczepanowski RH, Chazin WJ, Filipek A
Native Serotonin 5-HT2C Receptors are Expressed as Homodimers on the Apical Surface of Choroid Plexus Epithelial Cells.
1. Mol. Pharmacol. - published January 21, 2015
2. Herrick-Davis K, Grinde E, Lindsley T, Teitler M, Mancia F, Cowan A, Mazurkiewicz JE
Self-Determination in the T Cell Repertoire.
1. Immunity - published January 20, 2015
2. Birnbaum ME, Garcia KC
Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime.
1. Proc. Natl. Acad. Sci. U.S.A. - published January 20, 2015
2. Das DK, Feng Y, Mallis RJ, Li X, Keskin DB, Hussey RE, Brady SK, Wang JH, Wagner G, Reinherz EL, Lang MJ
Pharmacological activation of myosin II paralogs to correct cell mechanics defects.
1. Proc. Natl. Acad. Sci. U.S.A. - published January 20, 2015
2. Surcel A, Ng WP, West-Foyle H, Zhu Q, Ren Y, Avery LB, Krenc AK, Meyers DJ, Rock RS, Anders RA, Freel Meyers CL, Robinson DN
Effects of the electronic structure of five-membered N-heterocyclic carbenes on insertion of silanes and boranes into the NHC C-N bond.
1. Dalton Trans - published January 19, 2015
2. Iversen KJ, Wilson DJ, Dutton JL
Multiple assembly mechanisms anchor the KMN spindle checkpoint platform at human mitotic kinetochores.
1. J. Cell Biol. - published January 19, 2015
2. Kim S, Yu H
Membrane Trafficking: Licensing a Cargo Receptor for ER Export.
1. Curr. Biol. - published January 19, 2015
2. Fromme JC
Glycolytic enzymes localize to ribonucleoprotein granules in Drosophila germ cells, bind Tudor and protect from transposable elements.
1. EMBO Rep. - published January 18, 2015
2. Gao M, Thomson TC, Creed TM, Tu S, Loganathan SN, Jackson CA, McCluskey P, Lin Y, Collier SE, Weng Z, Lasko P, Ohi MD, Arkov AL
Insights into the molecular foundations of electrical excitation.
1. J. Mol. Biol. - published January 16, 2015
2. Gaudet R, Roux B, MinorJr DL
Development of a High Affinity, Non-covalent Biologic to Add Functionality to Fabs.
1. Sci Rep - published January 16, 2015
2. Avery KN, Zer C, Bzymek KP, Williams JC
MLL partial tandem duplication leukemia cells are sensitive to small molecule DOT1L inhibition.
1. Haematologica - published January 16, 2015
2. Kühn MW, Hadler MJ, Daigle SR, Koche RP, Krivtsov AV, Olhava EJ, Caligiuri MA, Huang G, Bradner JE, Pollock RM, Armstrong SA
Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes.
1. Virology - published January 15, 2015
2. Asmal M, Luedemann C, Lavine CL, Mach LV, Balachandran H, Brinkley C, Denny TN, Lewis MG, Anderson H, Pal R, Sok D, Le K, Pauthner M, Hahn BH, Shaw GM, Seaman MS, Letvin NL, Burton DR, Sodroski JG, Haynes BF, Santra S
Concurrent Cooperativity and Substrate Inhibition in the Epoxidation of Carbamazepine by Cytochrome P450 3A4 Active Site Mutants Inspired by Molecular Dynamics Simulations.
1. Biochemistry - published January 15, 2015
2. Müller CS, Knehans T, Davydov DR, Bounds PL, von Mandach U, Halpert JR, Caflisch A, Koppenol WH
New Role for the Ankyrin Repeat Revealed by a Study of the N-Formyltransferase from Providencia alcalifaciens.
1. Biochemistry - published January 15, 2015
2. Woodford CR, Thoden JB, Holden HM
Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells.
1. Nat Commun - published January 15, 2015
2. Küçük C, Jiang B, Hu X, Zhang W, Chan JK, Xiao W, Lack N, Alkan C, Williams JC, Avery KN, Kavak P, Scuto A, Sen E, Gaulard P, Staudt L, Iqbal J, Zhang W, Cornish A, Gong Q, Yang Q, Sun H, d'Amore F, Leppä S, Liu W, Fu K, de Leval L, McKeithan T, Chan WC
A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation.
1. Genes Dev. - published January 15, 2015
2. Zhang P, Chaturvedi CP, Tremblay V, Cramet M, Brunzelle JS, Skiniotis G, Brand M, Shilatifard A, Couture JF
DNA Sequence Modulates Geometrical Isomerism of the trans-8,9-Dihydro-8-(2,6-diamino-4-oxo-3,4-dihydropyrimid-5-yl-formamido)-9-hydroxy Aflatoxin B1 Adduct.
1. Chem. Res. Toxicol. - published January 14, 2015
2. Li L, Brown KL, Ma R, Stone MP
The Fate of NHC-Stabilized Dicarbon.
1. Chemistry - published January 14, 2015
2. Georgiou DC, Stringer BD, Hogan CF, Barnard PJ, Wilson DJ, Holzmann N, Frenking G, Dutton JL
On the stability of parainfluenza virus 5 F proteins.
1. J. Virol. - published January 14, 2015
2. Poor TA, Song AS, Welch BD, Kors CA, Jardetzky TS, Lamb RA
Phase Behavior of a Designed Cyclopropyl Analogue of Monoolein: Implications for Low-Temperature Membrane Protein Crystallization.
1. Angew. Chem. Int. Ed. Engl. - published January 12, 2015
2. Salvati Manni L, Zabara A, Osornio YM, Schöppe J, Batyuk A, Plückthun A, Siegel JS, Mezzenga R, Landau EM
Mechanistic insights into the recycling machine of the SNARE complex.
1. Nature - published January 12, 2015
2. Zhao M, Wu S, Zhou Q, Vivona S, Cipriano DJ, Cheng Y, Brunger AT
CASP10 - BCL::Fold efficiently samples topologies of large proteins.
1. Proteins - published January 10, 2015
2. Heinze S, Putnam D, Fischer A, Kohlmann T, Weiner B, Meiler J
Do's and don'ts of cryo-electron microscopy: a primer on sample preparation and high quality data collection for macromolecular 3D reconstruction.
1. J Vis Exp - published January 9, 2015
2. Cabra V, Samsó M
Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthesis.
1. Mol Cell - published January 8, 2015
2. Stefely JA, Reidenbach AG, Ulbrich A, Oruganty K, Floyd BJ, Jochem A, Saunders JM, Johnson IE, Minogue CE, Wrobel RL, Barber GE, Lee D, Li S, Kannan N, Coon JJ, Bingman CA, Pagliarini DJ
The strength and cooperativity of KIT ectodomain contacts determine normal ligand-dependent stimulation or oncogenic activation in cancer.
1. Mol Cell - published January 8, 2015
2. Reshetnyak AV, Opatowsky Y, Boggon TJ, Folta-Stogniew E, Tome F, Lax I, Schlessinger J
Membrane Anchoring of Epstein-Barr Virus gp42 Inhibits Fusion with B Cells Even with Increased Flexibility Allowed by Engineered Spacers.
1. MBio - published January 8, 2015
2. Rowe CL, Chen J, Jardetzky TS, Longnecker R
The kinase activity of the Ser/Thr kinase BUB1 promotes TGF-β signaling.
1. Sci Signal - published January 8, 2015
2. Nyati S, Schinske-Sebolt K, Pitchiaya S, Chekhovskiy K, Chator A, Chaudhry N, Dosch J, Van Dort ME, Varambally S, Kumar-Sinha C, Nyati MK, Ray D, Walter NG, Yu H, Ross BD, Rehemtulla A
Allosteric modulation of Ras and the PI3K/AKT/mTOR pathway: emerging therapeutic opportunities.
1. Front Physiol - published January 8, 2015
2. Hubbard PA, Moody CL, Murali R
Structural Analysis of the Binding of Type I, I1/2, and II Inhibitors to Eph Tyrosine Kinases.
1. ACS Med Chem Lett - published January 8, 2015
2. Dong J, Zhao H, Zhou T, Spiliotopoulos D, Rajendran C, Li XD, Huang D, Caflisch A
Caging Metal Ions with Visible Light-Responsive Nanopolymersomes.
1. Langmuir - published January 7, 2015
2. Griepenburg JC, Sood N, Vargo KB, Williams D, Rawson J, Therien MJ, Hammer DA, Dmochowski IJ
3D Structure of the Dihydropyridine Receptor of Skeletal Muscle.
1. Eur J Transl Myol - published January 7, 2015
2. Samsó M
Structural Biochemistry of a Fungal LOV Domain Photoreceptor Reveals an Evolutionarily Conserved Pathway Integrating Light and Oxidative Stress.
1. Structure - published January 6, 2015
2. Lokhandwala J, Hopkins HC, Rodriguez-Iglesias A, Dattenböck C, Schmoll M, Zoltowski BD
Designed Ankyrin Repeat Proteins (DARPins): Binding Proteins for Research, Diagnostics, and Therapy.
1. Annu. Rev. Pharmacol. Toxicol. - published January 6, 2015
2. Plückthun A
Simultaneously targeting tissue transglutaminase and kidney type glutaminase sensitizes cancer cells to acid toxicity and offers new opportunities for therapeutic intervention.
1. Mol Pharm - published January 5, 2015
2. Katt WP, Antonyak MA, Cerione RA
Cdc45 (cell division cycle protein 45) guards the gate of the Eukaryote Replisome helicase stabilizing leading strand engagement.
1. Proc. Natl. Acad. Sci. U.S.A. - published January 5, 2015
2. Petojevic T, Pesavento JJ, Costa A, Liang J, Wang Z, Berger JM, Botchan MR
Biochemical Reconstitution and Phylogenetic Comparison of Human SET1 Family Core Complexes Involved in Histone Methylation.
1. J. Biol. Chem. - published January 5, 2015
2. Shinsky SA, Monteith KE, Viggiano S, Cosgrove MS
Flies expand the repertoire of protein structures that bind ice.
1. Proc. Natl. Acad. Sci. U.S.A. - published January 5, 2015
2. Basu K, Graham LA, Campbell RL, Davies PL
Temperature-dependent innate defense against the common cold virus limits viral replication at warm temperature in mouse airway cells.
1. Proc. Natl. Acad. Sci. U.S.A. - published January 5, 2015
2. Foxman EF, Storer JA, Fitzgerald ME, Wasik BR, Hou L, Zhao H, Turner PE, Pyle AM, Iwasaki A
Information-Driven Modeling of Protein-Peptide Complexes.
1. Methods Mol. Biol. - published January 4, 2015
2. Trellet M, Melquiond AS, Bonvin AM
Alanine mutants of the interface residues of human thymidylate synthase decode key features of the binding mode of allosteric anticancer peptides.
1. J Med Chem - published January 2, 2015
2. Tochowicz A, Santucci M, Saxena P, Guaitoli G, Trande M, Finer-Moore J, Stroud RM, Costi MP
Three αSNAP and 10 ATP molecules are used in SNARE complex disassembly by N-ethylmaleimide-sensitive factor (NSF).
1. J Biol Chem - published January 2, 2015
2. Shah N, Colbert KN, Enos MD, Herschlag D, Weis WI
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.
1. Nature - published January 2, 2015
2. Konermann S, Brigham MD, Trevino AE, Joung J, Abudayyeh OO, Barcena C, Hsu PD, Habib N, Gootenberg JS, Nishimasu H, Nureki O, Zhang F
RNA-mediated epigenetic regulation of gene expression.
1. Nat. Rev. Genet. - published January 2, 2015
2. Holoch D, Moazed D
Protein synthesis. Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains.
1. Science - published January 2, 2015
2. Shen PS, Park J, Qin Y, Li X, Parsawar K, Larson MH, Cox J, Cheng Y, Lambowitz AM, Weissman JS, Brandman O, Frost A
A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay.
1. Mol Cell - published January 2, 2015
2. Ramage HR, Kumar GR, Verschueren E, Johnson JR, Von Dollen J, Johnson T, Newton B, Shah P, Horner J, Krogan NJ, Ott M
An algorithm to enumerate all possible protein conformations verifying a set of distance constraints.
1. BMC Bioinformatics - published January 2, 2015
2. Cassioli A, Bardiaux B, Bouvier G, Mucherino A, Alves R, Liberti L, Nilges M, Lavor C, Malliavin TE
Bacterial voltage-gated sodium channels (BacNa(V)s) from the soil, sea, and salt lakes enlighten molecular mechanisms of electrical signaling and pharmacology in the brain and heart.
1. J Mol Biol - published January 1, 2015
2. Payandeh J, Minor DL Jr
Metabolic syndrome is associated with and predicted by resting heart rate: a cross-sectional and longitudinal study.
1. Heart - published January 1, 2015
2. Jiang X, Liu X, Wu S, Zhang GQ, Peng M, Wu Y, Zheng X, Ruan C, Zhang W
A selective NMR probe to monitor the conformational transition from inactive to active kinase.
1. ACS Chem Biol - published January 1, 2015
2. Xie Q, Fulton DB, Andreotti AH
Structural requirements for the collagenase and elastase activity of cathepsin K and its selective inhibition by an exosite inhibitor.
1. Biochem J - published January 1, 2015
2. Sharma V, Panwar P, O'Donoghue AJ, Cui H, Guido RV, Craik CS, Brömme D
Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding.
1. Biochem J - published January 1, 2015
2. Visperas PR, Winger JA, Horton TM, Shah NH, Aum DJ, Tao A, Barros T, Yan Q, Wilson CG, Arkin MR, Weiss A, Kuriyan J
In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9.
1. Nat Biotechnol - published January 1, 2015
2. Swiech L, Heidenreich M, Banerjee A, Habib N, Li Y, Trombetta J, Sur M, Zhang F
Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.
1. Cancer Epidemiol Biomarkers Prev - published January 1, 2015
2. Peterlongo P, Chang-Claude J, Moysich KB, Rudolph A, Schmutzler RK, Simard J, Soucy P, Eeles RA, Easton DF, Hamann U, Wilkening S, Chen B, Rookus MA, Schmidt MK, van der Baan FH, Spurdle AB, Walker LC, Lose F, Maia AT, Montagna M, Matricardi L, Lubinski J, Jakubowska A, Gómez Garcia EB, Olopade OI, Nussbaum RL, Nathanson KL, Domchek SM, Rebbeck TR, Arun BK, Karlan BY, Orsulic S, Lester J, Chung WK, Miron A, Southey MC, Goldgar DE, Buys SS, Janavicius R, Dorfling CM, van Rensburg EJ, Ding YC, Neuhausen SL, Hansen TV, Gerdes AM, Ejlertsen B, Jønson L, Osorio A, Martínez-Bouzas C, Benitez J, Conway EE, Blazer KR, Weitzel JN, Manoukian S, Peissel B, Zaffaroni D, Scuvera G, Barile M, Ficarazzi F, Mariette F, Fortuzzi S, Viel A, Giannini G, Papi L, Martayan A, Tibiletti MG, Radice P, Vratimos A, Fostira F, Garber JE, Donaldson A, Brewer C, Foo C, Evans DG, Frost D, Eccles D, Brady A, Cook J, Tischkowitz M, Adlard J, Barwell J, Walker L, Izatt L, Side LE, Kennedy MJ, Rogers MT, Porteous ME, Morrison PJ, Platte R, Davidson R, Hodgson SV, Ellis S, Cole T, EMBRACE., Godwin AK, Claes K, Van Maerken T, Meindl A, Gehrig A, Sutter C, Engel C, Niederacher D, Steinemann D, Plendl H, Kast K, Rhiem K, Ditsch N, Arnold N, Varon-Mateeva R, Wappenschmidt B, Wang-Gohrke S, Bressac-de Paillerets B, Buecher B, Delnatte C, Houdayer C, Stoppa-Lyonnet D, Damiola F, Coupier I, Barjhoux L, Venat-Bouvet L, Golmard L, Boutry-Kryza N, Sinilnikova OM, Caron O, Pujol P, Mazoyer S, Belotti M, GEMO Study Collaborators., Piedmonte M, Friedlander ML, Rodriguez GC, Copeland LJ, de la Hoya M, Segura PP, Nevanlinna H, Aittomäki K, van Os TA, Meijers-Heijboer HE, van der Hout AH, Vreeswijk MP, Hoogerbrugge N, Ausems MG, van Doorn HC, Collée JM, HEBON., Olah E, Diez O, Blanco I, Lazaro C, Brunet J, Feliubadalo L, Cybulski C, Gronwald J, Durda K, Jaworska-Bieniek K, Sukiennicki G, Arason A, Chiquette J, Teixeira MR, Olswold C, Couch FJ, Lindor NM, Wang X, Szabo CI, Offit K, Corines M, Jacobs L, Robson ME, Zhang L, Joseph V, Berger A, Singer CF, Rappaport C, Kaulich DG, Pfeiler G, Tea MK, Phelan CM, Greene MH, Mai PL, Rennert G, Mulligan AM, Glendon G, Tchatchou S, Andrulis IL, Toland AE, Bojesen A, Pedersen IS, Thomassen M, Jensen UB, Laitman Y, Rantala J, von Wachenfeldt A, Ehrencrona H, Askmalm MS, Borg Å, Kuchenbaecker KB, McGuffog L, Barrowdale D, Healey S, Lee A, Pharoah PD, Chenevix-Trench G, KConFab Investigators., Antoniou AC, Friedman E
Identification of residues in the human respiratory syncytial virus fusion protein that modulate fusion activity and pathogenesis.
1. J Virol - published January 1, 2015
2. Hotard AL, Lee S, Currier MG, Crowe JE Jr, Sakamoto K, Newcomb DC, Peebles RS Jr, Plemper RK, Moore ML
The contractile ring coordinates curvature-dependent septum assembly during fission yeast cytokinesis.
1. Mol Biol Cell - published January 1, 2015
2. Zhou Z, Munteanu EL, He J, Ursell T, Bathe M, Huang KC, Chang F
Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter.
1. Nature - published January 1, 2015
2. Kim J, Wu S, Tomasiak TM, Mergel C, Winter MB, Stiller SB, Robles-Colmanares Y, Stroud RM, Tampé R, Craik CS, Cheng Y
Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia.
1. Blood - published January 1, 2015
2. Audrito V, Serra S, Brusa D, Mazzola F, Arruga F, Vaisitti T, Coscia M, Maffei R, Rossi D, Wang T, Inghirami G, Rizzi M, Gaidano G, Garcia JG, Wolberger C, Raffaelli N, Deaglio S
Terazosin activates Pgk1 and Hsp90 to promote stress resistance.
1. Nat Chem Biol - published January 1, 2015
2. Chen X, Zhao C, Li X, Wang T, Li Y, Cao C, Ding Y, Dong M, Finci L, Wang JH, Li X, Liu L
Electron cryotomography studies of maturing HIV-1 particles reveal the assembly pathway of the viral core.
1. J Virol - published January 1, 2015
2. Woodward CL, Cheng SN, Jensen GJ
Crystal structure of snake venom acetylcholinesterase in complex with inhibitory antibody fragment Fab410 bound at the peripheral site: evidence for open and closed states of a back door channel.
1. J Biol Chem - published January 1, 2015
2. Bourne Y, Renault L, Marchot P
Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance.
1. J Cell Sci - published January 1, 2015
2. Tang M, Li Y, Zhang Y, Chen Y, Huang W, Wang D, Zaug AJ, Liu D, Zhao Y, Cech TR, Ma W, Songyang Z
The RCSB Protein Data Bank: views of structural biology for basic and applied research and education.
1. Nucleic Acids Res - published January 1, 2015
2. Rose PW, Prlić A, Bi C, Bluhm WF, Christie CH, Dutta S, Green RK, Goodsell DS, Westbrook JD, Woo J, Young J, Zardecki C, Berman HM, Bourne PE, Burley SK
Structural analysis and binding properties of isoforms of tarin, the GNA-related lectin from Colocasia esculenta.
1. Biochim Biophys Acta - published January 1, 2015
2. Pereira PR, Winter HC, Verícimo MA, Meagher JL, Stuckey JA, Goldstein IJ, Paschoalin VM, Silva JT
C-MYC transcriptionally amplifies SOX2 target genes to regulate self-renewal in multipotent otic progenitor cells.
1. Stem Cell Reports - published January 1, 2015
2. Kwan KY, Shen J, Corey DP
Correction for Acharya et al., Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites.
1. J. Virol. - published January 1, 2015
2. Acharya P, Luongo TS, Georgiev IS, Matz J, Schmidt SD, Louder MK, Kessler P, Yang Y, McKee K, O'Dell S, Chen L, Baty D, Chames P, Martin L, Mascola JR, Kwong PD
Not Second Class: The First Class II MHC Crystal Structure.
1. J. Immunol. - published January 1, 2015
2. Bjorkman PJ
Common and distinct DNA-binding and regulatory activities of the BEN-solo transcription factor family.
1. Genes Dev - published January 1, 2015
2. Dai Q, Ren A, Westholm JO, Duan H, Patel DJ, Lai EC
From guide to target: molecular insights into eukaryotic RNA-interference machinery.
1. Nat Struct Mol Biol - published January 1, 2015
2. Ipsaro JJ, Joshua-Tor L
Uropathogenic Escherichia coli superinfection enhances the severity of mouse bladder infection.
1. PLoS Pathog - published January 1, 2015
2. Schwartz DJ, Conover MS, Hannan TJ, Hultgren SJ
Herpes simplex virus 1 Us3 deletion mutant is infective despite impaired capsid translocation to the cytoplasm.
1. Viruses - published January 1, 2015
2. Wild P, Leisinger S, de Oliveira AP, Schraner EM, Kaech A, Ackermann M, Tobler K
Bridged filaments of histone-like nucleoid structuring protein pause RNA polymerase and aid termination in bacteria.
1. Elife - published January 1, 2015
2. Kotlajich MV, Hron DR, Boudreau BA, Sun Z, Lyubchenko YL, Landick R
Structure calculation, refinement and validation using CcpNmr Analysis.
1. Acta Crystallogr D Biol Crystallogr - published January 1, 2015
2. Skinner SP, Goult BT, Fogh RH, Boucher W, Stevens TJ, Laue ED, Vuister GW
John A. Schellman, 1924-2014.
1. Biophys Chem - published January 1, 2015
2. Di Cera E
Use of miRNA Response Sequences to Block Off-target Replication and Increase the Safety of an Unattenuated, Glioblastoma-targeted Oncolytic HSV.
1. Mol Ther - published January 1, 2015
2. Mazzacurati L, Marzulli M, Reinhart B, Miyagawa Y, Uchida H, Goins WF, Li A, Kaur B, Caligiuri M, Cripe T, Chiocca N, Amankulor N, Cohen JB, Glorioso JC, Grandi P
Macrocycles: lessons from the distant past, recent developments, and future directions.
1. Chem Sci - published January 1, 2015
2. Yudin AK