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100 Member Publications for December 2014

A mutant Escherichia coli that attaches peptidoglycan to lipopolysaccharide and displays cell wall on its surface.
1. Elife - published December 31, 2014
2. Grabowicz M, Andres D, Lebar MD, Malojčić G, Kahne D, Silhavy TJ
Biochemistry That Times the Day.
1. Biochemistry - published December 30, 2014
2. Egli M, Johnson CH
Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells.
1. Proc. Natl. Acad. Sci. U.S.A. - published December 29, 2014
2. Stalnecker CA, Ulrich SM, Li Y, Ramachandran S, McBrayer MK, DeBerardinis RJ, Cerione RA, Erickson JW
Role of the Nuclease of Nontypeable Haemophilus influenzae in Dispersal of Organisms from Biofilms.
1. Infect. Immun. - published December 29, 2014
2. Cho C, Chande A, Gakhar L, Bakaletz LO, Jurcisek JA, Ketterer M, Shao J, Gotoh K, Foster E, Hunt J, O'Brien E, Apicella MA
Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins.
1. Nucleic Acids Res. - published December 29, 2014
2. Guilliam TA, Jozwiakowski SK, Ehlinger A, Barnes RP, Rudd SG, Bailey LJ, Skehel JM, Eckert KA, Chazin WJ, Doherty AJ
Structural Evidence for Asymmetrical Nucleotide Interactions in Nitrogenase.
1. J. Am. Chem. Soc. - published December 23, 2014
2. Tezcan FA, Kaiser JT, Howard JB, Rees DC
Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch.
1. Nature - published December 22, 2014
2. Bah A, Vernon RM, Siddiqui Z, Krzeminski M, Muhandiram R, Zhao C, Sonenberg N, Kay LE, Forman-Kay JD
Kernel-based logistic regression model for protein sequence without vectorialization.
1. Biostatistics - published December 22, 2014
2. Fong Y, Datta S, Georgiev IS, Kwong PD, Tomaras GD
Structural and Kinetic Basis of Steroid 17α,20-Lyase Activity in Teleost Fish Cytochrome P450 17A1 and Its Absence in Cytochrome P450 17A2.
1. J. Biol. Chem. - published December 22, 2014
2. Pallan PS, Nagy LD, Lei L, Gonzalez E, Kramlinger VM, Azumaya CM, Wawrzak Z, Waterman MR, Guengerich FP, Egli M
Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant.
1. Nature - published December 22, 2014
2. Yin J, Mobarec JC, Kolb P, Rosenbaum DM
Hooking She3p onto She2p for myosin-mediated cytoplasmic mRNA transport.
1. Proc. Natl. Acad. Sci. U.S.A. - published December 22, 2014
2. Singh N, Blobel G, Shi H
Bag6 complex contains a minimal tail-anchor-targeting module and a mock BAG domain.
1. Proc. Natl. Acad. Sci. U.S.A. - published December 22, 2014
2. Mock JY, Chartron JW, Zaslaver M, Xu Y, Ye Y, Clemons WM
Ethenoguanines Undergo Glycosylation by Nucleoside 2'-Deoxyribosyltransferases at Non-Natural Sites.
1. PLoS ONE - published December 19, 2014
2. Ye W, Paul D, Gao L, Seckute J, Sangaiah R, Jayaraj K, Zhang Z, Kaminski PA, Ealick SE, Gold A, Ball LM
The Stereochemical Basis of the Genetic Code and the (Mostly) Autotrophic Origin of Life.
1. Life (Basel) - published December 19, 2014
2. Fontecilla-Camps JC
Convergent Transcription at Intragenic Super-Enhancers Targets AID-Initiated Genomic Instability.
1. Cell - published December 18, 2014
2. Meng FL, Du Z, Federation A, Hu J, Wang Q, Kieffer-Kwon KR, Meyers RM, Amor C, Wasserman CR, Neuberg D, Casellas R, Nussenzweig MC, Bradner JE, Liu XS, Alt FW
Structural basis for the disruption of the Cerebral Cavernous Malformations 2 (CCM2) interaction with Krev Interaction Trapped 1 (KRIT1) by disease-associated mutations.
1. J. Biol. Chem. - published December 18, 2014
2. Fisher OS, Liu W, Zhang R, Stiegler AL, Ghedia S, Weber JL, Boggon TJ
Combinatorial Discovery of Cosolvent Systems for Production of Narrow Dispersion Thiolate-Protected Gold Nanoparticles.
1. ACS Comb Sci - published December 17, 2014
2. Wong OA, Compel WS, Ackerson CJ
Application of in situ diffraction in high-throughput structure determination platforms.
1. Methods Mol Biol - published December 16, 2014
2. Aller P, Sanchez-Weatherby J, Foadi J, Winter G, Lobley CM, Axford D, Ashton AW, Bellini D, Brandao-Neto J, Culurgioni S, Douangamath A, Duman R, Evans G, Fisher S, Flaig R, Hall DR, Lukacik P, Mazzorana M, McAuley KE, Mykhaylyk V, Owen RL, Paterson NG, Romano P, Sandy J, Sorensen T, von Delft F, Wagner A, Warren A, Williams M, Stuart DI, Walsh MA
Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery.
1. Elife - published December 15, 2014
2. Lin S, Staahl B, Alla RK, Doudna JA
Allosteric activation of ADAMTS13 by von Willebrand factor.
1. Proc. Natl. Acad. Sci. U.S.A. - published December 15, 2014
2. Muia J, Zhu J, Gupta G, Haberichter SL, Friedman KD, Feys HB, Deforche L, Vanhoorelbeke K, Westfield LA, Roth R, Tolia NH, Heuser JE, Sadler JE
Stable, uncleaved HIV-1 envelope glycoprotein gp140 forms a tightly folded trimer with a native-like structure.
1. Proc. Natl. Acad. Sci. U.S.A. - published December 15, 2014
2. Kovacs JM, Noeldeke E, Ha HJ, Peng H, Rits-Volloch S, Harrison SC, Chen B
Mycobacterial RNA polymerase forms unstable open promoter complexes that are stabilized by CarD.
1. Nucleic Acids Res. - published December 15, 2014
2. Davis E, Chen J, Leon K, Darst SA, Campbell EA
Regulation of the Rhp26ERCC6/CSB chromatin remodeler by a novel conserved leucine latch motif.
1. Proc. Natl. Acad. Sci. U.S.A. - published December 15, 2014
2. Wang L, Limbo O, Fei J, Chen L, Kim B, Luo J, Chong J, Conaway RC, Conaway JW, Ranish JA, Kadonaga JT, Russell P, Wang D
LocNES: A computational tool for locating classical NESs in CRM1 cargo proteins.
1. Bioinformatics - published December 15, 2014
2. Xu D, Marquis K, Pei J, Fu SC, Cağatay T, Grishin NV, Chook YM
Ionic strength independence of charge distributions in solvation of biomolecules.
1. J Chem Phys - published December 14, 2014
2. Virtanen JJ, Sosnick TR, Freed KF
Biochemical Properties and Biological Functions of FET Proteins.
1. Annu Rev Biochem - published December 11, 2014
2. Schwartz JC, Cech TR, Parker RR
A Nutrient-Driven tRNA Modification Alters Translational Fidelity and Genome-wide Protein Coding across an Animal Genus.
1. PLoS Biol. - published December 10, 2014
2. Zaborske JM, Bauer DuMont VL, Wallace EW, Pan T, Aquadro CF, Drummond DA
Insights Into Cytokine-Receptor Interactions from Cytokine Engineering.
1. Annu. Rev. Immunol. - published December 10, 2014
2. Spangler JB, Moraga I, Mendoza JL, Garcia KC
Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex.
1. Proc Natl Acad Sci U S A - published December 9, 2014
2. Sok D, van Gils MJ, Pauthner M, Julien JP, Saye-Francisco KL, Hsueh J, Briney B, Lee JH, Le KM, Lee PS, Hua Y, Seaman MS, Moore JP, Ward AB, Wilson IA, Sanders RW, Burton DR
Of social molecules: The interactive assembly of ASH1 mRNA-transport complexes in yeast.
1. RNA Biol - published December 9, 2014
2. Niedner A, Edelmann FT, Niessing D
Centralspindlin assembly and 2 phosphorylations on MgcRacGAP by Polo-like kinase 1 initiate Ect2 binding in early cytokinesis.
1. Cell Cycle - published December 9, 2014
2. Kim H, Guo F, Brahma S, Xing Y, Burkard ME
Whole-exome sequencing characterizes the landscape of somatic mutations and copy number alterations in adrenocortical carcinoma.
1. J. Clin. Endocrinol. Metab. - published December 9, 2014
2. Christofer Juhlin C, Goh G, Healy JM, Fonseca AL, Scholl UI, Stenman A, Kunstman JW, Brown TC, Overton JD, Mane SM, Nelson-Williams C, Bäckdahl M, Suttorp AC, Haase M, Choi M, Schlessinger J, Rimm DL, Höög A, Prasad ML, Korah R, Larsson C, Lifton RP, Carling T
Architecture and dynamics of the autophagic phosphatidylinositol 3-kinase complex.
1. Elife - published December 9, 2014
2. Baskaran S, Carlson LA, Stjepanovic G, Young LN, Kim DJ, Grob P, Stanley RE, Nogales E, Hurley JH
AF10 Regulates Progressive H3K79 Methylation and HOX Gene Expression in Diverse AML Subtypes.
1. Cancer Cell - published December 8, 2014
2. Deshpande AJ, Deshpande A, Sinha AU, Chen L, Chang J, Cihan A, Fazio M, Chen CW, Zhu N, Koche R, Dzhekieva L, Ibáñez G, Dias S, Banka D, Krivtsov A, Luo M, Roeder RG, Bradner JE, Bernt KM, Armstrong SA
The export receptor Crm1 forms a dimer to promote nuclear export of HIV RNA.
1. Elife - published December 8, 2014
2. Booth DS, Cheng Y, Frankel AD
Breaking the protein-RNA recognition code.
1. Cell Cycle - published December 8, 2014
2. Hennig J, Gebauer F, Sattler M
Microbial biosynthesis of medium-chain 1-alkenes by a nonheme iron oxidase.
1. Proc. Natl. Acad. Sci. U.S.A. - published December 8, 2014
2. Rui Z, Li X, Zhu X, Liu J, Domigan B, Barr I, Cate JH, Zhang W
Veritas per stucturam.
1. Annu. Rev. Biochem. - published December 8, 2014
2. Harrison SC
Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity.
1. J Biol Chem - published December 5, 2014
2. Skala W, Utzschneider DT, Magdolen V, Debela M, Guo S, Craik CS, Brandstetter H, Goettig P
Boron-Containing Enamine and Enamide Linchpins in the Synthesis of Nitrogen Heterocycles.
1. J. Am. Chem. Soc. - published December 5, 2014
2. St Denis JD, Zajdlik A, Tan J, Trinchera P, Lee CF, He Z, Adachi S, Yudin AK
Sequential conformational rearrangements in flavivirus membrane fusion.
1. Elife - published December 5, 2014
2. Chao LH, Klein DE, Schmidt AG, Peña JM, Harrison SC
β-catenin mediates stress resilience through Dicer1/microRNA regulation.
1. Nature - published December 4, 2014
2. Dias C, Feng J, Sun H, Shao NY, Mazei-Robison MS, Damez-Werno D, Scobie K, Bagot R, LaBonté B, Ribeiro E, Liu X, Kennedy P, Vialou V, Ferguson D, Peña C, Calipari ES, Koo JW, Mouzon E, Ghose S, Tamminga C, Neve R, Shen L, Nestler EJ
Adenylation of Maternally Inherited MicroRNAs by Wispy.
1. Mol. Cell - published December 4, 2014
2. Lee M, Choi Y, Kim K, Jin H, Lim J, Nguyen TA, Yang J, Jeong M, Giraldez AJ, Yang H, Patel DJ, Kim VN
Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.
1. Nature - published December 4, 2014
2. Brohawn SG, Campbell EB, MacKinnon R
Oxidative decomposition of Au25(SR)18 clusters in a catalytic context.
1. Chem. Commun. (Camb.) - published December 4, 2014
2. Dreier TA, Andrea Wong O, Ackerson CJ
Structure of the V. cholerae Na+-pumping NADH:quinone oxidoreductase.
1. Nature - published December 4, 2014
2. Steuber J, Vohl G, Casutt MS, Vorburger T, Diederichs K, Fritz G
A Quantitative Assay Reveals Ligand Specificity of the DNA scaffold repair protein XRCC1 and Efficient Disassembly of Complexes of XRCC1 and the Poly (ADP-ribose) polymerase 1 by PAR glycohydrolase.
1. J. Biol. Chem. - published December 4, 2014
2. Kim IK, Stegeman RA, Brosey CA, Ellenberger T
Metal ion and ligand binding of integrin α5β1.
1. Proc. Natl. Acad. Sci. U.S.A. - published December 4, 2014
2. Xia W, Springer TA
SPASM and Twitch Domains in AdoMet Radical Enzyme Structures.
1. J. Biol. Chem. - published December 4, 2014
2. Grell TA, Goldman PJ, Drennan CL
lncRNA maturation to initiate heterochromatin formation in the nucleolus is required for exit from pluripotency in ESCs.
1. Cell Stem Cell - published December 4, 2014
2. Savić N, Bär D, Leone S, Frommel SC, Weber FA, Vollenweider E, Ferrari E, Ziegler U, Kaech A, Shakhova O, Cinelli P, Santoro R
Uridylation by TUT4 and TUT7 Marks mRNA for Degradation.
1. Cell - published December 4, 2014
2. Lim J, Ha M, Chang H, Kwon SC, Simanshu DK, Patel DJ, Kim VN
Arrestin Expression in E. coli and Purification.
1. Curr Protoc Pharmacol - published December 3, 2014
2. Vishnivetskiy SA, Zhan X, Chen Q, Iverson TM, Gurevich VV
Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 proton channel.
1. J Am Chem Soc - published December 3, 2014
2. Wu Y, Canturk B, Jo H, Ma C, Gianti E, Klein ML, Pinto LH, Lamb RA, Fiorin G, Wang J, DeGrado WF
Putting a finger in the ring.
1. Nat. Struct. Mol. Biol. - published December 3, 2014
2. McCullough J, Sundquist WI
Lattice-free prediction of three-dimensional structure of programmed DNA assemblies.
1. Nat Commun - published December 3, 2014
2. Pan K, Kim DN, Zhang F, Adendorff MR, Yan H, Bathe M
Dodecyl maltopyranoside enabled purification of active human GABA type A receptors for deep and direct proteomic sequencing.
1. Mol. Cell Proteomics - published December 3, 2014
2. Zhang X, Miller KW
Specificity in endoplasmic reticulum-stress signaling in yeast entails a step-wise engagement of HAC1 mRNA to clusters of the stress sensor Ire1.
1. Elife - published December 3, 2014
2. van Anken E, Pincus D, Coyle S, Aragón T, Osman C, Lari F, Gómez Puerta S, Korennykh AV, Walter P
A 2-pyridone-amide inhibitor targets the glucose metabolism pathway of Chlamydia trachomatis.
1. mBio - published December 3, 2014
2. Engström P, Krishnan KS, Ngyuen BD, Chorell E, Normark J, Silver J, Bastidas RJ, Welch MD, Hultgren SJ, Wolf-Watz H, Valdivia RH, Almqvist F, Bergström S
The hepatitis C virus core protein inhibits adipose triglyceride lipase (ATGL)-mediated lipid mobilization and enhances the ATGL interaction with comparative gene identification 58 (CGI-58) and lipid droplets.
1. J Biol Chem - published December 2, 2014
2. Camus G, Schweiger M, Herker E, Harris C, Kondratowicz AS, Tsou CL, Farese RV Jr, Herath K, Previs SF, Roddy TP, Pinto S, Zechner R, Ott M
The Cys-Tyr cross-link of cysteine dioxygenase changes the optimal pH of the reaction without a structural change.
1. Biochemistry - published December 2, 2014
2. Davies CG, Fellner M, Tchesnokov EP, Wilbanks SM, Jameson GN
Atomic model of a cell-wall cross-linking enzyme in complex with an intact bacterial peptidoglycan.
1. J Am Chem Soc - published December 2, 2014
2. Schanda P, Triboulet S, Laguri C, Bougault CM, Ayala I, Callon M, Arthur M, Simorre JP
Molecular Basis for DPY-30 Association to COMPASS-like and NURF Complexes.
1. Structure - published December 2, 2014
2. Tremblay V, Zhang P, Chaturvedi CP, Thornton J, Brunzelle JS, Skiniotis G, Shilatifard A, Brand M, Couture JF
Structural analysis of the EGFR/HER3 heterodimer reveals the molecular basis for activating HER3 mutations.
1. Sci Signal - published December 2, 2014
2. Littlefield P, Liu L, Mysore V, Shan Y, Shaw DE, Jura N
Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.
1. Proc Natl Acad Sci U S A - published December 2, 2014
2. Perry JA, Kiezun A, Tonzi P, Van Allen EM, Carter SL, Baca SC, Cowley GS, Bhatt AS, Rheinbay E, Pedamallu CS, Helman E, Taylor-Weiner A, McKenna A, DeLuca DS, Lawrence MS, Ambrogio L, Sougnez C, Sivachenko A, Walensky LD, Wagle N, Mora J, de Torres C, Lavarino C, Dos Santos Aguiar S, Yunes JA, Brandalise SR, Mercado-Celis GE, Melendez-Zajgla J, Cárdenas-Cardós R, Velasco-Hidalgo L, Roberts CW, Garraway LA, Rodriguez-Galindo C, Gabriel SB, Lander ES, Golub TR, Orkin SH, Getz G, Janeway KA
A novel N-terminal extension in mitochondrial TRAP1 serves as a thermal regulator of chaperone activity.
1. Elife - published December 2, 2014
2. Partridge JR, Lavery LA, Elnatan D, Naber N, Cooke R, Agard DA
Recent findings on the mechanisms involved in tenofovir resistance.
1. Antivir Chem Chemother - published December 1, 2014
2. Iyidogan P, Anderson KS
Genome-Wide Mapping of the Distribution of CarD, RNAP σ^A, and RNAP β on the Mycobacterium smegmatis Chromosome using Chromatin Immunoprecipitation Sequencing.
1. Genom Data - published December 1, 2014
2. Landick R, Krek A, Glickman MS, Socci ND, Stallings CL
Comparative single-cell genomics reveals potential ecological niches for the freshwater acI Actinobacteria lineage.
1. ISME J - published December 1, 2014
2. Ghylin TW, Garcia SL, Moya F, Oyserman BO, Schwientek P, Forest KT, Mutschler J, Dwulit-Smith J, Chan LK, Martinez-Garcia M, Sczyrba A, Stepanauskas R, Grossart HP, Woyke T, Warnecke F, Malmstrom R, Bertilsson S, McMahon KD
Structural mechanisms in NLR inflammasome signaling.
1. Curr Opin Struct Biol - published December 1, 2014
2. Lechtenberg BC, Mace PD, Riedl SJ
Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG.
1. Nature - published December 1, 2014
2. Goyal P, Krasteva PV, Van Gerven N, Gubellini F, Van den Broeck I, Troupiotis-Tsaïlaki A, Jonckheere W, Péhau-Arnaudet G, Pinkner JS, Chapman MR, Hultgren SJ, Howorka S, Fronzes R, Remaut H
Sulfonylurea receptors regulate the channel pore in ATP-sensitive potassium channels via an intersubunit salt bridge.
1. Biochem J - published December 1, 2014
2. Lodwick D, Rainbow RD, Rubaiy HN, Al Johi M, Vuister GW, Norman RI
Investigation of the essentiality of glutamate racemase in Mycobacterium smegmatis.
1. J Bacteriol - published December 1, 2014
2. Li Y, Mortuza R, Milligan DL, Tran SL, Strych U, Cook GM, Krause KL
Structural and functional characterization of ybr137wp implicates its involvement in the targeting of tail-anchored proteins to membranes.
1. Mol Cell Biol - published December 1, 2014
2. Yeh YH, Lin TW, Li YC, Tung JY, Lin CY, Hsiao CD
Crystal structure of a signal recognition particle Alu domain in the elongation arrest conformation.
1. RNA - published December 1, 2014
2. Bousset L, Mary C, Brooks MA, Scherrer A, Strub K, Cusack S
A robust pipeline for rapid production of versatile nanobody repertoires.
1. Nat Methods - published December 1, 2014
2. Fridy PC, Li Y, Keegan S, Thompson MK, Nudelman I, Scheid JF, Oeffinger M, Nussenzweig MC, Fenyö D, Chait BT, Rout MP
A multiscale statistical mechanical framework integrates biophysical and genomic data to assemble cancer networks.
1. Nat Genet - published December 1, 2014
2. AlQuraishi M, Koytiger G, Jenney A, MacBeath G, Sorger PK
Solution structure of the YTH domain in complex with N6-methyladenosine RNA: a reader of methylated RNA.
1. Nucleic Acids Res - published December 1, 2014
2. Theler D, Dominguez C, Blatter M, Boudet J, Allain FH
Structural insight into cap-snatching and RNA synthesis by influenza polymerase.
1. Nature - published December 1, 2014
2. Reich S, Guilligay D, Pflug A, Malet H, Berger I, Crépin T, Hart D, Lunardi T, Nanao M, Ruigrok RW, Cusack S
Structure of influenza A polymerase bound to the viral RNA promoter.
1. Nature - published December 1, 2014
2. Pflug A, Guilligay D, Reich S, Cusack S
Crystal structure of a BRAF kinase domain monomer explains basis for allosteric regulation.
1. Nat. Struct. Mol. Biol. - published December 1, 2014
2. Thevakumaran N, Lavoie H, Critton DA, Tebben A, Marinier A, Sicheri F, Therrien M
A 2,2'-bipyridine coordination complex of [ICl2](+)
1. Dalton Trans - published December 1, 2014
2. Shaw AJ, Corbo R, Wilson DJ, Dutton JL
Immune response to HHV-6 and implications for immunotherapy.
1. Curr Opin Virol - published December 1, 2014
2. Becerra A, Gibson L, Stern LJ, Calvo-Calle JM
Relation of ABO blood groups to the severity of coronary atherosclerosis: an Gensini score assessment.
1. Atherosclerosis - published December 1, 2014
2. Gong P, Luo SH, Li XL, Guo YL, Zhu CG, Xu RX, Li S, Dong Q, Liu G, Chen J, Zeng RX, Li JJ
A computational analysis of the structural determinants of APOBEC3's catalytic activity and vulnerability to HIV-1 Vif.
1. Virology - published December 1, 2014
2. Shandilya SM, Bohn MF, Schiffer CA
An adenosine nucleoside analogue NITD008 inhibits EV71 proliferation.
1. Antiviral Res - published December 1, 2014
2. Shang L, Wang Y, Qing J, Shu B, Cao L, Lou Z, Gong P, Sun Y, Yin Z
Particle migration analysis in iterative classification of cryo-EM single-particle data.
1. J Struct Biol - published December 1, 2014
2. Chen B, Shen B, Frank J
High-sensitivity C-reactive protein mediates in part the impact of ABO blood group on coronary artery disease.
1. Int J Cardiol - published December 1, 2014
2. Gong P, Li S, Luo SH, Zhang Y, Li XL, Guo YL, Zhu CG, Xu RX, Dong Q, Liu G, Zeng RX, Li JJ
Specificity in circadian clock feedback from targeted reconstitution of the NuRD corepressor.
1. Mol Cell - published December 1, 2014
2. Kim JY, Kwak PB, Weitz CJ
Internal  Dynamics of Dynactin's CAP-Gly is Regulated by Microtubules and Plus End Tracking Protein EB1.
1. J. Biol. Chem. - published December 1, 2014
2. Yan S, Zhang H, Hou G, Ahmed S, Williams JC, Polenova T
Arf GTPases and their effectors: assembling multivalent membrane-binding platforms.
1. Curr Opin Struct Biol - published December 1, 2014
2. Cherfils J
Conformational dynamics of a crystalline protein from microsecond-scale molecular dynamics simulations and diffuse X-ray scattering.
1. Proc. Natl. Acad. Sci. U.S.A. - published December 1, 2014
2. Wall ME, Van Benschoten AH, Sauter NK, Adams PD, Fraser JS, Terwilliger TC
Structure of a mammalian ryanodine receptor.
1. Nature - published December 1, 2014
2. Zalk R, Clarke OB, Georges AD, Grassucci RA, Reiken S, Mancia F, Hendrickson WA, Frank J, Marks AR
Tightly integrated single- and multi-crystal data collection strategy calculation and parallelized data processing in JBluIce beamline control system.
1. J Appl Crystallogr - published December 1, 2014
2. Pothineni SB, Venugopalan N, Ogata CM, Hilgart MC, Stepanov S, Sanishvili R, Becker M, Winter G, Sauter NK, Smith JL, Fischetti RF
Transmembrane helix straightening and buckling underlies activation of mechanosensitive and thermosensitive K(2P) channels.
1. Neuron - published December 1, 2014
2. Lolicato M, Riegelhaupt PM, Arrigoni C, Clark KA, Minor DL Jr
NMR analysis of base-pair opening kinetics in DNA.
1. Curr Protoc Nucleic Acid Chem - published December 1, 2014
2. Szulik MW, Voehler M, Stone MP
Detection of hydrogen bonds in dynamic regions of RNA by NMR spectroscopy.
1. Curr Protoc Nucleic Acid Chem - published December 1, 2014
2. Dallmann A, Sattler M
Mutations in global regulators lead to metabolic selection during adaptation to complex environments.
1. PLoS Genet - published December 1, 2014
2. Saxer G, Krepps MD, Merkley ED, Ansong C, Deatherage Kaiser BL, Valovska MT, Ristic N, Yeh PT, Prakash VP, Leiser OP, Nakhleh L, Gibbons HS, Kreuzer HW, Shamoo Y
Putting numbers on chromatin and its interacting partners.
1. Methods - published December 1, 2014
2. Luger K
De novo design of a transmembrane Zn²⁺-transporting four-helix bundle.
1. Science - published December 1, 2014
2. Joh NH, Wang T, Bhate MP, Acharya R, Wu Y, Grabe M, Hong M, Grigoryan G, DeGrado WF
Antibodies: Computer-Aided Prediction of Structure and Design of Function.
1. Microbiol Spectr - published December 1, 2014
2. Sevy AM, Meiler J