Member Publications
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96 Member Publications for November 2014
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A flexible, scalable method for preparation of homogeneous aminoacylated tRNAs.
- Methods Enzymol - published November 30, 2014
- Zhang J, Ferré-D'Amaré AR
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Crystallographic analysis of TPP riboswitch binding by small-molecule ligands discovered through fragment-based drug discovery approaches.
- Methods Enzymol - published November 30, 2014
- Warner KD, Ferré-D'Amaré AR
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Genome editing. The new frontier of genome engineering with CRISPR-Cas9.
- Science - published November 28, 2014
- Doudna JA, Charpentier E
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Scrambling free combinatorial labeling of alanine-β, isoleucine-δ1, leucine-proS and valine-proS methyl groups for the detection of long range NOEs.
- J. Biomol. NMR - published November 28, 2014
- Kerfah R, Plevin MJ, Pessey O, Hamelin O, Gans P, Boisbouvier J
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DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.
- Science - published November 28, 2014
- Wang R, Persky NS, Yoo B, Ouerfelli O, Smogorzewska A, Elledge SJ, Pavletich NP
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Structure refinement and membrane positioning of selectively labeled OmpX in phospholipid nanodiscs.
- J. Biomol. NMR - published November 28, 2014
- Hagn F, Wagner G
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Cancerous epithelial cell lines shed extracellular vesicles with a bimodal size distribution that is sensitive to glutamine inhibition.
- Phys Biol - published November 27, 2014
- Santana SM, Antonyak MA, Cerione RA, Kirby BJ
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Fluorescent Probes of the Apoptolidins and their Utility in Cellular Localization Studies.
- Angew. Chem. Int. Ed. Engl. - published November 27, 2014
- DeGuire SM, Earl DC, Du Y, Crews BA, Jacobs AT, Ustione A, Daniel C, Chong KM, Marnett LJ, Piston DW, Bachmann BO, Sulikowski GA
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Differential inhibition of Arabidopsis superoxide dismutases by peroxynitrite-mediated tyrosine nitration.
- J. Exp. Bot. - published November 26, 2014
- Holzmeister C, Gaupels F, Geerlof A, Sarioglu H, Sattler M, Durner J, Lindermayr C
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Lysyl hydroxylase 3 modifies lysine residues to facilitate oligomerization of mannan-binding lectin.
- PLoS One - published November 25, 2014
- Risteli M, Ruotsalainen H, Bergmann U, Venkatraman Girija U, Wallis R, Myllylä R
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The safety dance: biophysics of membrane protein folding and misfolding in a cellular context.
- Q. Rev. Biophys. - published November 25, 2014
- Schlebach JP, Sanders CR
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The Solution Structure of the Transducin-α/UNC119 Complex suggests occlusion of the Gβ1γ1-binding sites.
- FEBS J. - published November 25, 2014
- Cheguru P, Majumder A, Yadav R, Gopalakrishna KN, Gakhar L, Artemyev NO
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Structure of l-Serine Dehydratase from Legionella pneumophila: Novel Use of the C-Terminal Cysteine as an Intrinsic Competitive Inhibitor.
- Biochemistry - published November 24, 2014
- Thoden JB, Holden HM, Grant GA
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Crystal Structure of a TSH Receptor Monoclonal Antibody: Insight into Graves' Disease Pathogenesis.
- Mol. Endocrinol. - published November 24, 2014
- Chen CR, Hubbard P, Salazar LM, McLachlan SM, Murali R, Rapoport B
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Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies.
- Nat. Struct. Mol. Biol. - published November 24, 2014
- Bird GH, Irimia A, Ofek G, Kwong PD, Wilson IA, Walensky LD
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Molecular architecture of the αβ T cell receptor-CD3 complex.
- Proc. Natl. Acad. Sci. U.S.A. - published November 24, 2014
- Birnbaum ME, Berry R, Hsiao YS, Chen Z, Shingu-Vazquez MA, Yu X, Waghray D, Fischer S, McCluskey J, Rossjohn J, Walz T, Garcia KC
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PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.
- Nat Commun - published November 22, 2014
- Jiang Y, Wang Y, Wang T, Hawke DH, Zheng Y, Li X, Zhou Q, Majumder S, Bi E, Liu DX, Huang S, Lu Z
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Fitting Nonlinear Ordinary Differential Equation Models with Random Effects and Unknown Initial Conditions Using the Stochastic Approximation Expectation-Maximization (SAEM) Algorithm.
- Psychometrika - published November 22, 2014
- Chow SM, Lu Z, Sherwood A, Zhu H
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In-line alignment and Mg(2+) coordination at the cleavage site of the env22 twister ribozyme.
- Nat Commun - published November 21, 2014
- Ren A, Košutić M, Rajashankar KR, Frener M, Santner T, Westhof E, Micura R, Patel DJ
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Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module.
- Cell Res. - published November 21, 2014
- Wang H, Curran EC, Hinds TR, Wang EH, Zheng N
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Origins of life: RNA made in its own mirror image.
- Nature - published November 20, 2014
- Shelke SA, Piccirilli JA
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Genome engineering using CRISPR-Cas9 system.
- Methods Mol Biol - published November 20, 2014
- Cong L, Zhang F
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Fission yeast RNA triphosphatase reads an Spt5 CTD code.
- RNA - published November 20, 2014
- Doamekpor SK, Schwer B, Sanchez AM, Shuman S, Lima CD
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Self-assembled monolayers improve protein distribution on holey carbon cryo-EM supports.
- Sci Rep - published November 19, 2014
- Meyerson JR, Rao P, Kumar J, Chittori S, Banerjee S, Pierson J, Mayer ML, Subramaniam S
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Mechano-Transduction: From Molecules to Tissues.
- PLoS Biol. - published November 19, 2014
- Pruitt BL, Dunn AR, Weis WI, Nelson WJ
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A structural atlas of kinases inhibited by clinically approved drugs.
- Methods Enzymol - published November 18, 2014
- Wang Q, Zorn JA, Kuriyan J
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Comprehensive Identification of Phosphorylation Sites on theNumb Endocytic Adaptor Protein.
- Proteomics - published November 18, 2014
- Krieger JR, Taylor P, Moran MF, McGlade CJ
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Lipid-linked cell wall precursors regulate membrane association of bacterial actin MreB.
- Nat. Chem. Biol. - published November 17, 2014
- Schirner K, Eun YJ, Dion M, Luo Y, Helmann JD, Garner EC, Walker S
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G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments.
- Proc. Natl. Acad. Sci. U.S.A. - published November 17, 2014
- Ivanov P, O'Day E, Emara MM, Wagner G, Lieberman J, Anderson P
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A model for the generation and interconversion of ER morphologies.
- Proc. Natl. Acad. Sci. U.S.A. - published November 17, 2014
- Shemesh T, Klemm RW, Romano FB, Wang S, Vaughan J, Zhuang X, Tukachinsky H, Kozlov MM, Rapoport TA
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Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody.
- Proc. Natl. Acad. Sci. U.S.A. - published November 17, 2014
- Malito E, Biancucci M, Faleri A, Ferlenghi I, Scarselli M, Maruggi G, Lo Surdo P, Veggi D, Liguori A, Santini L, Bertoldi I, Petracca R, Marchi S, Romagnoli G, Cartocci E, Vercellino I, Savino S, Spraggon G, Norais N, Pizza M, Rappuoli R, Masignani V, Bottomley MJ
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MicroRNA silencing for cancer therapy targeted to the tumour microenvironment.
- Nature - published November 17, 2014
- Cheng CJ, Bahal R, Babar IA, Pincus Z, Barrera F, Liu C, Svoronos A, Braddock DT, Glazer PM, Engelman DM, Saltzman WM, Slack FJ
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In vitro enzymology of Cas9.
- Methods Enzymol - published November 16, 2014
- Anders C, Jinek M
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Genome editing using Cas9 nickases.
- Methods Enzymol - published November 16, 2014
- Trevino AE, Zhang F
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The Bcl-2 family: structures, interactions and targets for drug discovery.
- Apoptosis - published November 15, 2014
- Kvansakul M, Hinds MG
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Novel Prodrug-Like Fusion Toxin with Protease-Sensitive Bioorthogonal PEGylation for Tumor Targeting.
- Bioconjug. Chem. - published November 14, 2014
- Stefan N, Zimmermann M, Simon M, Zangemeister-Wittke U, Plückthun A
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A high-yield co-expression system for the purification of an intact Drs2p-Cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate.
- PLoS One - published November 14, 2014
- Azouaoui H, Montigny C, Ash MR, Fijalkowski F, Jacquot A, Grønberg C, López-Marqués RL, Palmgren MG, Garrigos M, le Maire M, Decottignies P, Gourdon P, Nissen P, Champeil P, Lenoir G
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Structure-Guided DOT1L Probe Optimization by Label-Free Ligand Displacement.
- ACS Chem. Biol. - published November 14, 2014
- Yi JS, Federation AJ, Qi J, Dhe-Paganon S, Hadler M, Xu X, St Pierre R, Varca AC, Wu L, Marineau JJ, Smith WB, Souza A, Chory EJ, Armstrong SA, Bradner JE
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Pin1-mediated Sp1 phosphorylation by CDK1 increases Sp1 stability and decreases its DNA-binding activity during mitosis.
- Nucleic Acids Res. - published November 14, 2014
- Yang HC, Chuang JY, Jeng WY, Liu CI, Wang AH, Lu PJ, Chang WC, Hung JJ
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X-ray structure of a calcium-activated TMEM16 lipid scramblase.
- Nature - published November 12, 2014
- Brunner JD, Lim NK, Schenck S, Duerst A, Dutzler R
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Analysis of Nidogen-1/Laminin γ1 Interaction by Cross-Linking, Mass Spectrometry, and Computational Modeling Reveals Multiple Binding Modes.
- PLoS ONE - published November 12, 2014
- Lössl P, Kölbel K, Tänzler D, Nannemann D, Ihling CH, Keller MV, Schneider M, Zaucke F, Meiler J, Sinz A
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Structural basis for extracellular cis and trans RPTPσ signal competition in synaptogenesis.
- Nat Commun - published November 12, 2014
- Coles CH, Mitakidis N, Zhang P, Elegheert J, Lu W, Stoker AW, Nakagawa T, Craig AM, Jones EY, Aricescu AR
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Fission yeast profilin is tailored to facilitate actin assembly by the cytokinesis formin Cdc12.
- Mol. Biol. Cell - published November 12, 2014
- Bestul AJ, Christensen JR, Grzegorzewska AP, Burke TA, Sees JA, Carroll RT, Sirotkin V, Keenan RJ, Kovar DR
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Fragment-Based Screening of the Bromodomain of ATAD2.
- J. Med. Chem. - published November 11, 2014
- Harner MJ, Chauder BA, Phan J, Fesik SW
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The Specialized Hsp70 (HscA) Interdomain Linker Binds to Its Nucleotide-Binding Domain and Stimulates ATP Hydrolysis in Both cis and trans Configurations.
- Biochemistry - published November 11, 2014
- Alderson TR, Kim JH, Cai K, Frederick RO, Tonelli M, Markley JL
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Predicted optical performance of the GM/CA@APS micro-focus beamline.
- J Phys Conf Ser - published November 11, 2014
- Fischetti RF, Yoder D, Xu S, Makarov O, Ogata C, Smith JL
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Force Field Model of Periodic Trends in Biomolecular Halogen Bonds.
- J Phys Chem B - published November 10, 2014
- Scholfield MR, Ford MC, Vander Zanden CM, Billman MM, Ho PS, Rappé AK
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Structural determinants of integrin β-subunit specificity for latent TGF-β
- Nat. Struct. Mol. Biol. - published November 10, 2014
- Dong X, Hudson NE, Lu C, Springer TA
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Structure and function of a single-chain, multi-domain long-chain acyl-CoA carboxylase.
- Nature - published November 10, 2014
- Tran TH, Hsiao YS, Jo J, Chou CY, Dietrich LE, Walz T, Tong L
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The contribution of αβ-tubulin curvature to microtubule dynamics.
- J. Cell Biol. - published November 10, 2014
- Brouhard GJ, Rice LM
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Lis1 regulates dynein by sterically blocking its mechanochemical cycle.
- Elife - published November 8, 2014
- Toropova K, Zou S, Roberts AJ, Redwine WB, Goodman BS, Reck-Peterson SL, Leschziner AE
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Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter.
- Nat Commun - published November 8, 2014
- Grossmann N, Vakkasoglu AS, Hulpke S, Abele R, Gaudet R, Tampé R
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Casting inorganic structures with DNA molds.
- Science - published November 7, 2014
- Sun W, Boulais E, Hakobyan Y, Wang WL, Guan A, Bathe M, Yin P
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Phylogenomics resolves the timing and pattern of insect evolution.
- Science - published November 7, 2014
- Misof B, Liu S, Meusemann K, Peters RS, Donath A, Mayer C, Frandsen PB, Ware J, Flouri T, Beutel RG, Niehuis O, Petersen M, Izquierdo-Carrasco F, Wappler T, Rust J, Aberer AJ, Aspöck U, Aspöck H, Bartel D, Blanke A, Berger S, Böhm A, Buckley TR, Calcott B, Chen J, Friedrich F, Fukui M, Fujita M, Greve C, Grobe P, Gu S, Huang Y, Jermiin LS, Kawahara AY, Krogmann L, Kubiak M, Lanfear R, Letsch H, Li Y, Li Z, Li J, Lu H, Machida R, Mashimo Y, Kapli P, McKenna DD, Meng G, Nakagaki Y, Navarrete-Heredia JL, Ott M, Ou Y, Pass G, Podsiadlowski L, Pohl H, von Reumont BM, Schütte K, Sekiya K, Shimizu S, Slipinski A, Stamatakis A, Song W, Su X, Szucsich NU, Tan M, Tan X, Tang M, Tang J, Timelthaler G, Tomizuka S, Trautwein M, Tong X, Uchifune T, Walzl MG, Wiegmann BM, Wilbrandt J, Wipfler B, Wong TK, Wu Q, Wu G, Xie Y, Yang S, Yang Q, Yeates DK, Yoshizawa K, Zhang Q, Zhang R, Zhang W, Zhang Y, Zhao J, Zhou C, Zhou L, Ziesmann T, Zou S, Li Y, Xu X, Zhang Y, Yang H, Wang J, Wang J, Kjer KM, Zhou X
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Insights Into the Specificity of Lysine Acetyltransferases.
- J. Biol. Chem. - published November 7, 2014
- Tucker AC, Taylor KC, Rank KC, Rayment I, Escalante-Semerena JC
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Structural Dynamics as a Contributor to Error-prone Replication by a RNA-dependent RNA Polymerase.
- J. Biol. Chem. - published November 6, 2014
- Moustafa IM, Korboukh VK, Arnold JJ, Smidansky ED, Marcotte LL, Gohara DW, Yang X, Sánchez-Farrán MA, Filman D, Maranas JK, Boehr DD, Hogle JM, Colina CM, Cameron CE
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Allosteric communication in the dynein motor domain.
- Cell - published November 6, 2014
- Bhabha G, Cheng HC, Zhang N, Moeller A, Liao M, Speir JA, Cheng Y, Vale RD
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A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis.
- Cell - published November 6, 2014
- Gujral TS, Chan M, Peshkin L, Sorger PK, Kirschner MW, MacBeath G
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Regulation of the NaV1.5 cytoplasmic domain by calmodulin.
- Nat Commun - published November 5, 2014
- Gabelli SB, Boto A, Kuhns VH, Bianchet MA, Farinelli F, Aripirala S, Yoder J, Jakoncic J, Tomaselli GF, Amzel LM
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Versatile in vitro system to study translocation and functional integration of bacterial outer membrane proteins.
- Nat Commun - published November 5, 2014
- Norell D, Heuck A, Tran-Thi TA, Götzke H, Jacob-Dubuisson F, Clausen T, Daley DO, Braun V, Müller M, Fan E
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WEDGE: An anticoagulant thrombin mutant produced by autoactivation.
- J. Thromb. Haemost. - published November 5, 2014
- Wood DC, Pelc LA, Pozzi N, Wallisch M, Verbout NG, Tucker EI, Gruber A, Di Cera E
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Direct Visualization of Trans-Synaptic Neurexin-Neuroligin Interactions during Synapse Formation.
- J. Neurosci. - published November 5, 2014
- Tsetsenis T, Boucard AA, Araç D, Brunger AT, Südhof TC
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Distinct N-terminal regions of the exomer secretory vesicle cargo Chs3 regulate its trafficking itinerary.
- Front Cell Dev Biol - published November 4, 2014
- Weiskoff AM, Fromme JC
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Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia.
- Proc. Natl. Acad. Sci. U.S.A. - published November 4, 2014
- Yashiro-Ohtani Y, Wang H, Zang C, Arnett KL, Bailis W, Ho Y, Knoechel B, Lanauze C, Louis L, Forsyth KS, Chen S, Chung Y, Schug J, Blobel GA, Liebhaber SA, Bernstein BE, Blacklow SC, Liu XS, Aster JC, Pear WS
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Modified T4 Lysozyme Fusion Proteins Facilitate G Protein-Coupled Receptor Crystallogenesis.
- Structure - published November 4, 2014
- Thorsen TS, Matt R, Weis WI, Kobilka BK
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Artificial accelerators of the molecular chaperone hsp90 facilitate rate-limiting conformational transitions.
- Angew. Chem. Int. Ed. Engl. - published November 3, 2014
- Zierer BK, Weiwad M, Rübbelke M, Freiburger L, Fischer G, Lorenz OR, Sattler M, Richter K, Buchner J
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Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.
- Proc. Natl. Acad. Sci. U.S.A. - published November 3, 2014
- Olivier NB, Altman RB, Noeske J, Basarab GS, Code E, Ferguson AD, Gao N, Huang J, Juette MF, Livchak S, Miller MD, Prince DB, Cate JH, Buurman ET, Blanchard SC
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Insights into substrate and metal binding from the crystal structure of cyanobacterial aldehyde deformylating oxygenase with substrate bound.
- ACS Chem Biol - published November 2, 2014
- Buer BC, Paul B, Das D, Stuckey JA, Marsh EN
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Current and potential treatments for ubiquitous but neglected herpesvirus infections.
- Chem Rev - published November 2, 2014
- Gable JE, Acker TM, Craik CS
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An α-helical core encodes the dual functions of the chlamydial protein IncA.
- J Biol Chem - published November 2, 2014
- Ronzone E, Wesolowski J, Bauler LD, Bhardwaj A, Hackstadt T, Paumet F
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Controlling olefin isomerization in the heck reaction with neopentyl phosphine ligands.
- J Org Chem - published November 2, 2014
- Lauer MG, Thompson MK, Shaughnessy KH
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Biochemical, mechanistic, and spectroscopic characterization of metallo-β-lactamase VIM-2.
- Biochemistry - published November 2, 2014
- Aitha M, Marts AR, Bergstrom A, Møller AJ, Moritz L, Turner L, Nix JC, Bonomo RA, Page RC, Tierney DL, Crowder MW
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Disorder and residual helicity alter p53-Mdm2 binding affinity and signaling in cells.
- Nat. Chem. Biol. - published November 2, 2014
- Borcherds W, Theillet FX, Katzer A, Finzel A, Mishall KM, Powell AT, Wu H, Manieri W, Dieterich C, Selenko P, Loewer A, Daughdrill GW
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The role of the hypoxia response in shaping retinal vascular development in the absence of Norrin/Frizzled4 signaling.
- Invest Ophthalmol Vis Sci - published November 2, 2014
- Rattner A, Wang Y, Zhou Y, Williams J, Nathans J
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Protein interference applications in cellular and developmental biology using DARPins that recognize GFP and mCherry.
- Biol Open - published November 2, 2014
- Brauchle M, Hansen S, Caussinus E, Lenard A, Ochoa-Espinosa A, Scholz O, Sprecher SG, Plückthun A, Affolter M
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A bacteriophage tubulin harnesses dynamic instability to center DNA in infected cells.
- Elife - published November 2, 2014
- Erb ML, Kraemer JA, Coker JK, Chaikeeratisak V, Nonejuie P, Agard DA, Pogliano J
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RNA targeting by the type III-A CRISPR-Cas Csm complex of Thermus thermophilus.
- Mol Cell - published November 2, 2014
- Staals RH, Zhu Y, Taylor DW, Kornfeld JE, Sharma K, Barendregt A, Koehorst JJ, Vlot M, Neupane N, Varossieau K, Sakamoto K, Suzuki T, Dohmae N, Yokoyama S, Schaap PJ, Urlaub H, Heck AJ, Nogales E, Doudna JA, Shinkai A, van der Oost J
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Molecular architecture and function of the SEA complex, a modulator of the TORC1 pathway.
- Mol Cell Proteomics - published November 1, 2014
- Algret R, Fernandez-Martinez J, Shi Y, Kim SJ, Pellarin R, Cimermancic P, Cochet E, Sali A, Chait BT, Rout MP, Dokudovskaya S
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Isolation of dengue virus-specific memory B cells with live virus antigen from human subjects following natural infection reveals the presence of diverse novel functional groups of antibody clones.
- J Virol - published November 1, 2014
- Smith SA, de Alwis AR, Kose N, Jadi RS, de Silva AM, Crowe JE Jr
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Integrative structure-function mapping of the nucleoporin Nup133 suggests a conserved mechanism for membrane anchoring of the nuclear pore complex.
- Mol Cell Proteomics - published November 1, 2014
- Kim SJ, Fernandez-Martinez J, Sampathkumar P, Martel A, Matsui T, Tsuruta H, Weiss TM, Shi Y, Markina-Inarrairaegui A, Bonanno JB, Sauder JM, Burley SK, Chait BT, Almo SC, Rout MP, Sali A
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Specific aromatic foldamers potently inhibit spontaneous and seeded Aβ42 and Aβ43 fibril assembly.
- Biochem J - published November 1, 2014
- Seither KM, McMahon HA, Singh N, Wang H, Cushman-Nick M, Montalvo GL, DeGrado WF, Shorter J
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Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo.
- J. Virol. - published November 1, 2014
- Rudicell RS, Kwon YD, Ko SY, Pegu A, Louder MK, Georgiev IS, Wu X, Zhu J, Boyington JC, Chen X, Shi W, Yang ZY, Doria-Rose NA, McKee K, O'Dell S, Schmidt SD, Chuang GY, Druz A, Soto C, Yang Y, Zhang B, Zhou T, Todd JP, Lloyd KE, Eudailey J, Roberts KE, Donald BR, Bailer RT, Ledgerwood J, NISC Comparative Sequencing Program, Mullikin JC, Shapiro L, Koup RA, Graham BS, Nason MC, Connors M, Haynes BF, Rao SS, Roederer M, Kwong PD, Mascola JR, Nabel GJ
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Structural characterization by cross-linking reveals the detailed architecture of a coatomer-related heptameric module from the nuclear pore complex.
- Mol Cell Proteomics - published November 1, 2014
- Shi Y, Fernandez-Martinez J, Tjioe E, Pellarin R, Kim SJ, Williams R, Schneidman-Duhovny D, Sali A, Rout MP, Chait BT
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Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
- J. Virol. - published November 1, 2014
- Acharya P, Tolbert WD, Gohain N, Wu X, Yu L, Liu T, Huang W, Huang CC, Kwon YD, Louder RK, Luongo TS, McLellan JS, Pancera M, Yang Y, Zhang B, Flinko R, Foulke JS, Sajadi MM, Kamin-Lewis R, Robinson JE, Martin L, Kwong PD, Guan Y, DeVico AL, Lewis GK, Pazgier M
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Origins of fluorescence in evolved bacteriophytochromes.
- J Biol Chem - published November 1, 2014
- Bhattacharya S, Auldridge ME, Lehtivuori H, Ihalainen JA, Forest KT
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Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA.
- EMBO J - published November 1, 2014
- Jones CP, Ferré-D'Amaré AR
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Crystal structure of the vitamin B3 transporter PnuC, a full-length SWEET homolog.
- Nat Struct Mol Biol - published November 1, 2014
- Jaehme M, Guskov A, Slotboom DJ
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Rapid modification of the pET-28 expression vector for ligation independent cloning using homologous recombination in Saccharomyces cerevisiae.
- Plasmid - published November 1, 2014
- Gay G, Wagner DT, Keatinge-Clay AT, Gay DC
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Trigger-helix folding pathway and SI3 mediate catalysis and hairpin-stabilized pausing by Escherichia coli RNA polymerase.
- Nucleic Acids Res - published November 1, 2014
- Windgassen TA, Mooney RA, Nayak D, Palangat M, Zhang J, Landick R
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Purification, crystallization and preliminary X-ray crystallographic analysis of the flagellar accessory protein FlaH from the methanogenic archaeon Methanocaldococcus jannaschii.
- Acta Crystallogr F Struct Biol Commun - published November 1, 2014
- Meshcheryakov VA, Yoon YH, Matsunami H, Wolf M
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Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants.
- J Exp Med - published November 1, 2014
- Klein F, Nogueira L, Nishimura Y, Phad G, West AP Jr, Halper-Stromberg A, Horwitz JA, Gazumyan A, Liu C, Eisenreich TR, Lehmann C, Fätkenheuer G, Williams C, Shingai M, Martin MA, Bjorkman PJ, Seaman MS, Zolla-Pazner S, Karlsson Hedestam GB, Nussenzweig MC
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Role of DNA sequence in chromatin remodeling and the formation of nucleosome-free regions.
- Genes Dev - published November 1, 2014
- Lorch Y, Maier-Davis B, Kornberg RD
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Picomolar Inhibitors of HIV-1 Reverse Transcriptase: Design and Crystallography of Naphthyl Phenyl Ethers.
- ACS Med Chem Lett - published November 1, 2014
- Lee WG, Frey KM, Gallardo-Macias R, Spasov KA, Bollini M, Anderson KS, Jorgensen WL
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Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation.
- mBio - published November 1, 2014
- Trajtenberg F, Albanesi D, Ruétalo N, Botti H, Mechaly AE, Nieves M, Aguilar PS, Cybulski L, Larrieux N, de Mendoza D, Buschiazzo A
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Rhinovirus uses a phosphatidylinositol 4-phosphate/cholesterol counter-current for the formation of replication compartments at the ER-Golgi interface.
- Cell Host Microbe - published November 1, 2014
- Roulin PS, Lötzerich M, Torta F, Tanner LB, van Kuppeveld FJ, Wenk MR, Greber UF
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Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis.
- EBioMedicine - published November 1, 2014
- Hannan TJ, Roberts PL, Riehl TE, van der Post S, Binkley JM, Schwartz DJ, Miyoshi H, Mack M, Schwendener RA, Hooton TM, Stappenbeck TS, Hansson GC, Stenson WF, Colonna M, Stapleton AE, Hultgren SJ