Member Publications

Jump to specific year:

62 Member Publications for August

Previous Month

Vaccination with Acinetobacter baumannii adhesin Abp2D provides protection against catheter-associated urinary tract infection.
1. Nat Commun - published August 9, 2025
2. Timm MR, Tamadonfar KO, Nye TM, Villicaña JB, Pinkner JS, Dodson KW, Ellebedy AH, Hultgren SJ
Structure and function of the human apoptotic scramblase Xkr4.
1. Nat Commun - published August 8, 2025
2. Chakraborty S, Feng Z, Lee S, Alvarenga OE, Panda A, Zhang S, Bruni R, Khelashvili G, Gupta K, Accardi A
Author Correction: An extensive disulfide bond network prevents tail contraction in Agrobacterium tumefaciens phage Milano.
1. Nat Commun - published August 7, 2025
2. Sonani RR, Palmer LK, Esteves NC, Horton AA, Sebastian AL, Kelly RJ, Wang F, Kreutzberger MAB, Russell WK, Leiman PG, Scharf BE, Egelman EH
Establishment of the phagophore-ERES membrane contact site initiates phagophore elongation.
1. Nat Struct Mol Biol - published August 7, 2025
2. Gómez-Sánchez R, Chumpen Ramirez S, Vargas Duarte P, Hu Y, Mari M, Olschewski K, Hardenberg R, Fromme JC, Ungermann C, Reggiori F
Impact of an Evidence-Based Large Language Model (LLM) Diagnostic Decision Support System: A Randomised Controlled Trial.
1. Stud Health Technol Inform - published August 7, 2025
2. Ahn S, Park J, Hur S, Jung KY, Lee JH, Choi SW, Son MH, Kang MJ, Kim YJ, Park H, Cha WC, Yoo J
Genomics-informed drug-repurposing strategy identifies two therapeutic targets for preventing liver disease associated with metabolic dysfunction.
1. Am J Hum Genet - published August 7, 2025
2. Seagle HM, Akerele AT, DeCorte JA, Hellwege JN, Breeyear JH, Kim J, Levin MG, Khodursky S, Bress A, Lee KM, Meiler J, Gill D, Lee JS, Heberer K, Miller DR, Reaven PD, Chang KM, Lynch JA, VA Million Veteran Program, Khankari NK, Shuey MM, Edwards TL, Vujkovic M
Dynamic intraligand binding reveals a new function for PDZ domains.
1. Structure - published August 7, 2025
2. Fuentes EJ
Principles of cotranslational mitochondrial protein import.
1. Cell - published August 7, 2025
2. Zhu Z, Mallik S, Stevens TA, Huang R, Levy ED, Shan SO
Structure of the TXNL1-bound proteasome.
1. Nat Struct Mol Biol - published August 6, 2025
2. Gao J, Nardone C, Yip MCJ, Chino H, Gu X, Mirman Z, Rale MJ, Paulo JA, Elledge SJ, Shao S
Clonotype-enriched somatic hypermutations drive affinity maturation of a public human antibody targeting an occluded sarbecovirus epitope.
1. Cell Rep - published August 6, 2025
2. Rao VN, Sapse IA, Cohn H, Yoo DK, Tong P, Clark JJ, Bozarth B, Chen Y, Srivastava K, Singh G, Krammer F, Simon V, Wesemann DR, Bajic G, Coelho CH
Surface delivery quantification reveals distinct trafficking efficiencies among clustered protocadherin isoforms.
1. Proc Natl Acad Sci U S A - published August 5, 2025
2. May EJ, Gaudet R
Cytosolic- and membrane-localized oxidized indole-3-acetic acid formation regulates developmental auxin transients.
1. Plant Physiol - published August 5, 2025
2. Jenness M, Tayengwa R, House L, Cao S, Báez RR, Nath S, Pritchard CA, Sharma A, Mergner J, Rivière F, Meinnel T, Giglione C, Kuster B, Blakeslee JJ, Nemhauser JL, Zheng N, Murphy AS, Peer WA
Identification and characterization of nanobodies specific for the human ubiquitin-like ISG15 protein.
1. J Biol Chem - published August 5, 2025
2. Gan J, Dabhade P, Wijne C, McKibben W, Draganov SD, Alrawili H, Jim Sun ZY, Houghton JW, Tate EW, Le Gall C, Suresh P, Pishesha N, Pinto-Fernández A, Schwartz TU, Ploegh HL
A rapid and highly sensitive CRISPR assay utilizing Cas12a orthologs for the detection of Novel Duck Reovirus.
1. Talanta - published August 5, 2025
2. Wang Y, Fu L, Li S, Tao D, Gong P, Yang Y, Ruan J, Xie S, Wang C, He D
Small molecule dysregulation of ClpP activity via bidirectional allosteric pathways.
1. Structure - published August 5, 2025
2. Barghash MM, Mabanglo MF, Hoff SE, Brozdnychenko D, Wong KS, Binepal G, Ip P, Shen J, Furukawa T, Katayama H, Trudel V, Tan J, Yudin AK, Gray-Owen SD, Sakuda S, Batey RA, Vahidi S, Bonomi M, Houry WA
Structure of the microtubule-anchoring factor NEDD1 bound to the γ-tubulin ring complex.
1. J Cell Biol - published August 4, 2025
2. Muñoz-Hernández H, Xu Y, Pellicer Camardiel A, Zhang D, Xue A, Aher A, Walker E, Marxer F, Kapoor TM, Wieczorek M
A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores.
1. J Cell Biol - published August 4, 2025
2. Stewart MG, Carrier JS, Zahm JA, Harrison SC, Miller MP
The rapidly expanding role of LC3-interacting regions in autophagy.
1. J Cell Biol - published August 4, 2025
2. North BJ, Fracchiolla D, Ragusa MJ, Martens S, Shoemaker CJ
SMAC mimetics induce human macrophages to phagocytose live cancer cells.
1. Immunother Adv - published August 4, 2025
2. Liu SY, Hulsman MPM, Leyendecker P, Chang E, Donovan KA, Strobel F, Dougan J, Fischer ES, Dougan M, Dougan SK, Qiang L
Real-time capture of σ(N) transcription initiation intermediates reveals mechanism of ATPase-driven activation by limited unfolding.
1. Nat Commun - published August 4, 2025
2. Mueller AU, Molina N, Nixon BT, Darst SA
Development of a novel therapy for systolic heart failure.
1. EMBO Mol Med - published August 4, 2025
2. Pollock C, Wang X, Alsaraji H, Menassa J, Mbogo G, Angage D, Richards B, Glab J, Datta KK, Theodoridis L, Petrovski S, Donner D, Lizarme-Salas Y, Du XJ, Foley M, Smith BJ, Abbott B, Puthalakath H
Identification of Aspartyl-tRNA Synthetase as Co-purifying with Wheat Germ eIF2.
1. MicroPubl Biol - published August 4, 2025
2. Papoulas O, Marcotte EM, Browning KS
Clostridioides difficile toxin A and toxin B inhibit toxin-specific adaptive immune responses through glucosyltransferase-dependent activity.
1. bioRxiv - published August 2, 2025
2. Maslanka JR, Londregan JA, Denny JE, Hulit EN, Mdluli NV, Peritore-Galve FC, Alam MZ, Alameh MG, Lacy DB, Zackular JP, Abt MC
12,13-diHOME protects against the age-related decline in cardiovascular function via attenuation of CaMKII.
1. Nat Commun - published August 2, 2025
2. Nirengi S, Buck B, Das D, Peres Valgas da Silva C, Calyeca J, Baer LA, Huang HL, Vidal P, Dewal RS, Pinckard KM, Félix-Soriano E, Hernandez-Saavedra D, Gerea A, Dathathreya K, Duarte-Sanmiguel S, Saldana TA, Hookfin HL, Gorr MW, Bussberg V, Aristizabal-Henao JJ, Kiebish MA, Middelbeek RJW, Goodyear LJ, Coen PM, Chinthalapudi K, Wold LE, Mora AL, Hund TJ, Gallego-Perez D, Stanford KI
Amyloid fibril structures link CHCHD10 and CHCHD2 to neurodegeneration.
1. Nat Commun - published August 2, 2025
2. Lv G, Sayles NM, Huang Y, Mancinelli C, McAvoy K, Shneider NA, Manfredi G, Kawamata H, Eliezer D
Modeling protein conformational ensembles by guiding AlphaFold2 with Double Electron Electron Resonance (DEER) distance distributions.
1. Nat Commun - published August 2, 2025
2. Wu T, Stein RA, Kao TY, Brown B, Mchaourab HS
Lyotropy as a Design Consideration for Ultra-Small Protein Nanoparticles via Electrohydrodynamic Jetting.
1. Macromol Rapid Commun - published August 1, 2025
2. Iqbal MH, Zelaya J, Ong Q, Stellacci F, Lahann J
CryoSift - An accessible and automated CNN-driven tool for cryo-EM 2D class selection.
1. bioRxiv - published August 1, 2025
2. Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA
PARP7 inhibition stabilizes STAT1/STAT2 and relieves experimental autoimmune encephalomyelitis in mice.
1. Cell Rep - published August 1, 2025
2. Xu J, Yu T, Yue Z, Lu X, Zhang Y, Wang L, Åhrling SS, Smith MR, Li YC, Matthews J, Lin H
Cryo-EM structure of the tissue factor/factor VIIa complex with a factor X mimetic reveals a novel allosteric mechanism.
1. Blood - published August 1, 2025
2. Sedzro JC, Photenhauer AL, Birkle F, Meze K, Mortenson A, Duckworth C, Wen PC, Kearns S, Cianfrocco MA, Tajkhorshid E, Ohi MD, Morrissey JH
AcrIF11 is a potent CRISPR-specific ADP-ribosyltransferase encoded by phage and plasmid.
1. mBio - published August 1, 2025
2. Chen DF, Roe LT, Yuping L, Borges AL, Zhang JY, Babbar P, Maji S, Stevens MGV, Correy GJ, Diolaiti ME, Smith DH, Ashworth A, Stroud RM, Kelly MJS, Bondy-Denomy J, Fraser JS
A virtual screening strategy to repurpose antifolate compounds as W. Bancrofti DHFR inhibitors.
1. Bioorg Med Chem Lett - published August 1, 2025
2. Kwarteng S, Wilhelm J, Salama M, Salama M, Hollander K, Anderson KS, Goodey NM, Frey KM
Infection with Mycobacterium tuberculosis alters the antibody response to HIV-1.
1. PLoS Pathog - published August 1, 2025
2. Zeeb M, Kusejko K, Hartnack S, Pasin C, Abela IA, Rusert P, Liechti T, Kadelka C, Notter J, Eichenberger A, Hoffmann M, Hirsch HH, Calmy A, Cavassini M, Labhardt ND, Bernasconi E, Günthard HF, Kouyos RD, Trkola A, Nemeth J, Swiss HIV Cohort Study
Structural Basis of PPARγ-Mediated Transcriptional Repression by the Covalent Inverse Agonist FX-909.
1. J Med Chem - published August 1, 2025
2. Laughlin ZT, Arifova L, Munoz-Tello P, Yu X, Giridhar MNK, Dong J, Harp JM, Zhu D, Kamenecka TM, Kojetin DJ
Decoding Protein-Peptide Interactions Using a Large, Target-Agnostic Yeast Surface Display Library.
1. ACS Chem Biol - published August 1, 2025
2. Hurley JD, Shlosman I, Lakshminarayan M, Zhao Z, Yue H, Nowak RP, Fischer ES, Kruse AC
PDB-IHM: A System for Deposition, Curation, Validation, and Dissemination of Integrative Structures.
1. J Mol Biol - published August 1, 2025
2. Vallat B, Webb BM, Zalevsky A, Tangmunarunkit H, Sekharan MR, Voinea S, Shafaeibejestan A, Sagendorf J, Hoch JC, Kurisu G, Morris KL, Velankar S, Kesselman C, Burley SK, Berman HM, Sali A
Protein Data Bank Japan: Computational Resources for Analysis of Protein Structures.
1. J Mol Biol - published August 1, 2025
2. Bekker GJ, Nagao C, Shirota M, Nakamura T, Katayama T, Kihara D, Kinoshita K, Kurisu G
An intrinsically disordered region of Ubp10 regulates its binding and activity on ubiquitinated histone substrates.
1. Protein Sci - published August 1, 2025
2. Faustino AM, Nune M, Merino-Urteaga R, Manriquez-Sandoval E, Poyton M, Ha T, Wolberger C, Fried SD
E-FTMap: A Protein Structure Based Pharmacophore Identification Server for Guiding Fragment Expansion.
1. J Mol Biol - published August 1, 2025
2. Khan O, Jones G, Kozakov D, Beglov D, Joseph-McCarthy D, Vajda S
Glia-derived noncanonical fatty acid binding protein modulates brain lipid storage and clearance.
1. Sci Adv - published August 1, 2025
2. Yin J, Chen HL, Grigsby-Brown A, He Y, Cotten ML, Short J, Dermady A, Lei J, Gibbs M, Cheng ES, Zhang D, Long C, Tabet J, Xu L, Zhong T, Abzalimov R, Haider M, Sun R, He Y, Zhou Q, Tjandra N, Yuan Q
A pan-respiratory virus attachment inhibitor with high potency in human airway models and in vivo.
1. Sci Adv - published August 1, 2025
2. Mathez G, Silva PJ, Carlen V, Deloizy C, Prompt C, Hubart A, Rocha-Pereira J, Galloux M, Le Goffic R, Stellacci F, Cagno V
TOX, through a glass, darkly.
1. Front Immunol - published August 1, 2025
2. Hogan PG, Villalobos Reveles B, Arteaga Vazquez LJ
The molecular basis of lamin-specific chromatin interactions.
1. Nat Struct Mol Biol - published August 1, 2025
2. Wang B, Kronenberg-Tenga R, Rosti V, Di Patrizio Soldateschi E, Luo Q, Iannacchero UM, Pinet L, Eibauer M, Boujemaa-Paterski R, Schuler B, Lanzuolo C, Medalia O
Structure Modeling Protocols for Protein Multimer and RNA in CASP16 With Enhanced MSAs, Model Ranking, and Deep Learning.
1. Proteins - published August 1, 2025
2. Kagaya Y, Nakamura T, Verburgt J, Jain A, Terashi G, Punuru P, Tugolukova E, Park JH, Saha A, Huang D, Kihara D
Structure of CFTR bound to (R)-BPO-27 unveils a pore-blockage mechanism.
1. Nat Commun - published August 1, 2025
2. Young PG, Fiedorczuk K, Chen J
Identification of the seven critical residues that control ZIKV-DENV cross-reactivity to engineer a non-cross-reactive ZIKV vaccine.
1. Cell Rep - published August 1, 2025
2. Grinyo-Escuer A, Reddy S, Chenine AL, Whitbeck JC, Jacobsen S, Sheetz A, Doolan K, Norden DM, Frey N, Holtsberg FW, Aman MJ, Fink K, Diamond MS, Schieffelin JS, Crowe JE Jr, Davidson E, Doranz BJ
Structural basis for anaerobic alkane activation by a multisubunit glycyl radical enzyme.
1. Proc Natl Acad Sci U S A - published August 1, 2025
2. Andorfer MC, Levitz TS, Liu J, Chakraborty A, King-Roberts DT, Nweneka D, Imrich CN, Drennan CL
A cell isolation method from Ligusticum chuanxiong Hort. suitable for obtaining high-quality RNA for Smart-seq.
1. Plant Methods - published August 1, 2025
2. Li R, Wu M, Chen S, Huang L, Wang C, Yu Z, Huang F, Liu X, Zhu N, Song C, Jiang G, Yin X
Immunologic profiling of the infant immune response to whole-cell and acellular pertussis vaccines.
1. NPJ Vaccines - published August 1, 2025
2. Creech CB, Leguia M, Goll JB, Howard LM, Vila-Sanjurjo A, Yoder S, Juarez D, Garcia-Glaessner A, Gelber CE, Jimenez-Truque N, Cherikh S, Gil AI, Crowe JE, Cotos RC, Edwards KM, Lanata CF
Identification and Characterization of a Metal Binding-Independent Rift Valley Fever Virus Endonuclease Inhibitor.
1. ACS Infect Dis - published August 1, 2025
2. Kirby CD, Liu G, Fatma F, Pedlow MR, G-Dayanandan N, Sharma N, Frey ZD, Rush RE, Cardinale SC, Krezel AM, Hartman AL, Bowlin TL, Leung DW, Amarasinghe GK
FakeRotLib: Expedient Noncanonical Amino Acid Parametrization in Rosetta.
1. J Chem Inf Model - published August 1, 2025
2. Bell EW, Brown BP, Meiler J
Client-scaffold interactions suppress aggregation of a client protein in model condensates.
1. Proc Natl Acad Sci U S A - published August 1, 2025
2. Ahmed R, Hudson RP, Forman-Kay JD, Kay LE
Targeted delivery of diverse biomolecules with engineered bacterial nanosyringes.
1. Nat Biotechnol - published August 1, 2025
2. Kreitz J, Yang V, Friedrich MJ, Pham J, Macrae RK, Zhang F
Lipid interactions and gating hysteresis suggest a physiological role for mechanosensitive channel YnaI.
1. Nat Commun - published August 1, 2025
2. Will N, Hiotis G, Nakayama Y, Angiulli G, Zhou Z, Cox CD, Martinac B, Walz T
Irreversible furin cleavage site exposure renders immature tick-borne flaviviruses fully infectious.
1. Nat Commun - published August 1, 2025
2. Holoubek J, Salát J, Matkovic M, Bednář P, Novotný P, Hradilek M, Majerová T, Rosendal E, Eyer L, Fořtová A, Beránková M, Bell-Sakyi L, Överby AK, Cavalli A, Bonomi M, Rey FA, Růžek D
Structure guided functional analysis of the S. cerevisiae Mre11 complex.
1. Nat Commun - published August 1, 2025
2. Hohl M, Yu Y, Kuryavyi V, Patel DJ, Petrini J
Deciphering the RNA recognition by Musashi-1 to design protein and RNA variants for in vitro and in vivo applications.
1. Nucleic Acids Res - published August 1, 2025
2. Pérez-Ràfols A, Pérez-Ropero G, Cerofolini L, Sperotto L, Roca-Martínez J, Higuera-Rodríguez RA, Russomanno P, Kaiser W, Vranken W, Danielson UH, Provenzani A, Martelli T, Sattler M, Buijs J, Fragai M
DNA TOPOISOMERASE II MUTATIONS IN CANCER: STRUCTURAL IMPACT AND DRUG RESPONSE IN HIGH-GRADE SEROUS OVARIAN CARCINOMA.
1. J Mol Biol - published August 1, 2025
2. Mazzoleni V, Boichard A, Lamour V
Mechanistic insights into the small-molecule inhibition of influenza A virus entry.
1. Proc Natl Acad Sci U S A - published August 1, 2025
2. Xu Y, Anirudhan V, Gaisina IN, Du H, Alqarni S, Moore TW, Caffrey M, Manicassamy B, Zhou T, Rong L, Xu K
Expanding the cytokine receptor alphabet reprograms T cells into diverse states.
1. Nature - published August 1, 2025
2. Zhao Y, Ogishi M, Pal A, Su LL, Tao P, Jiang H, Rodriguez GE, Chen X, Sun Q, Rysavy LW, Limsuwannarot S, Waghray D, Kalbasi A, Garcia KC
Clonal expansion and diversification of germinal center and memory B cell responses to booster immunization in primates.
1. Cell Rep - published August 1, 2025
2. Deimel LP, Nishimura Y, Silva Santos GS, Baharani VA, Hernandez B, Oliveira TY, MacLean AJ, Canis M, Shawraz S, Gazumyan A, Hartweger H, Bieniasz PD, Hatziioannou T, Martin MA, Nussenzweig MC
Spontaneous and experimental models of lymph node metastasis.
1. Nat Protoc - published August 1, 2025
2. Breuer CB, Xiong Z, Wang A, Rodriguez GE, Abhiraman GC, Garcia KC, Reticker-Flynn NE