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97 Member Publications for October

Previous Month

A high throughput single molecule platform to study DNA supercoiling effect on protein-DNA interactions.
1. bioRxiv - published October 2, 2024
2. Lee H, Hwang J, Rashid F, London JA, Fishel R, Berger JM, Myong S, Ha T
CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.
1. bioRxiv - published October 2, 2024
2. Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Bravo CP, Bose R, Travaglini KJ, Lam VL, Goodness D, Dixon G, Marzette E, Jin J, Tian R, Tse E, Abskharon R, Pan H, Carroll EC, Lawrence RE, Gestwicki JE, Eisenberg D, Kanaan NM, Southworth DR, Gross JD, Gan L, Swaney DL, Kampmann M
In-Situ Structure and Topography of AMPA Receptor Scaffolding Complexes Visualized by CryoET.
1. bioRxiv - published October 2, 2024
2. Held RG, Liang J, Esquivies L, Khan YA, Wang C, Azubel M, Brunger AT
Cryo-EM structures of the Plasmodium falciparum apicoplast DNA polymerase.
1. J Mol Biol - published October 2, 2024
2. Lo CY, Ung AR, Koley T, Nelson SW, Gao Y
APOA2 Increases Cholesterol Efflux Capacity to Plasma HDL by Displacing the C-terminus of Resident APOA1.
1. J Lipid Res - published October 2, 2024
2. Sarkar S, Morris J, You Y, Sexmith H, Street SE, Thibert SM, Attah IK, Hutchinson Bunch CM, Novikova I, Evans J, Shah AS, Gordon SM, Segrest JP, Bornfeldt KE, Vaisar T, Heinecke JW, Davidson WS, Melchior JT
Identification, characterization, and structure of a tRNA splicing enzyme RNA 5'-OH kinase from the pathogenic fungi Mucorales.
1. RNA - published October 2, 2024
2. Ghosh S, Wimberly-Gard G, Jacewicz A, Schwer B, Shuman S
An interpretable deep learning framework identifies proteomic drivers of Alzheimer's disease.
1. Front Cell Dev Biol - published October 2, 2024
2. Panizza E, Cerione RA
Dramatic changes in mitochondrial subcellular location and morphology accompany activation of the CO(2) concentrating mechanism.
1. Proc Natl Acad Sci U S A - published October 2, 2024
2. Findinier J, Joubert LM, Fakhimi N, Schmid MF, Malkovskiy AV, Chiu W, Burlacot A, Grossman AR
Conformation matters: siRNAs with antisense strands with 5'-(E)-vinyl-phosphonate-α-L-LNA elicit stronger RNAi-mediated gene silencing than those with 5'-(E)-vinyl-phosphonate-LNA.
1. Chem Commun (Camb) - published October 2, 2024
2. Datta D, Kumar P, Mandal S, Krampert M, Egli M, Hrdlicka PJ, Manoharan M
Conformational cycle of a protease-containing ABC transporter in lipid nanodiscs reveals the mechanism of cargo-protein coupling.
1. Nat Commun - published October 2, 2024
2. Zhang R, Jagessar KL, Brownd M, Polasa A, Stein RA, Moradi M, Karakas E, Mchaourab HS
DiffModeler: large macromolecular structure modeling for cryo-EM maps using a diffusion model.
1. Nat Methods - published October 2, 2024
2. Wang X, Zhu H, Terashi G, Taluja M, Kihara D
Reconstitution of Rab11-FIP4 Expression Rescues Cellular Homeostasis in Cystinosis.
1. Mol Cell Biol - published October 2, 2024
2. Rahman F, Johnson JL, Ait Kbaich M, Meneses-Salas E, Shukla A, Chen D, Kiosses WB, Gavathiotis E, Cuervo AM, Cherqui S, Catz SD
Discovery of Truncated Cyclic Peptides Targeting an Induced-Fit Pocket on PCSK9.
1. ChemMedChem - published October 2, 2024
2. Grosche P, Flyer AN, Gattlen R, Xu M, Golosov AA, Vera V, Pickett S, Brousseau ME, Chopra R, Clairmont KB, Koch A, Liu E, Reid P, Perry L, Yang L, Yang Q, Monovich LG
Clamping Pol ε to the leading strand.
1. Nat Struct Mol Biol - published October 2, 2024
2. Singh N, Johansson E
Dissecting the Conformational Heterogeneity of Stem-Loop Substructures of the Fifth Element in the 5'-Untranslated Region of SARS-CoV-2.
1. J Am Chem Soc - published October 2, 2024
2. Mertinkus KR, Oxenfarth A, Richter C, Wacker A, Mata CP, Carazo JM, Schlundt A, Schwalbe H
3D Cryo-Electron Microscopy Reveals the Structure of a 3-Fluorenylmethyloxycarbonyl Zipper Motif Ensuring the Self-Assembly of Tripeptide Nanofibers.
1. ACS Nano - published October 2, 2024
2. Bigo-Simon A, Estrozi LF, Chaumont A, Schurhammer R, Schoehn G, Combet J, Schmutz M, Schaaf P, Jierry L
Characterization of Medusavirus encoded histones reveals nucleosome-like structures and a unique linker histone.
1. Nat Commun - published October 2, 2024
2. Toner CM, Hoitsma NM, Weerawarana S, Luger K
Structurally Minimalized and Druglike TGase2 Inhibitors Based on 7-Aminoquinoline-5,8-dione Scaffolds for the Treatment of Diabetic Retinopathy.
1. J Med Chem - published October 2, 2024
2. Kang J, Jeon HY, Lee J, Bae S, Park GY, Min KJ, Joo J, Lee AJ, Kim HJ, Im CY, Kim EB, Lee JH, Hwang JS, Lee S, Lee JY, Navals P, Keillor JW, Ha KS, Song M
Orientation-dependent CD45 inhibition with viral and engineered ligands.
1. Sci Immunol - published October 2, 2024
2. Borowska MT, Liu LD, Caveney NA, Jude KM, Kim WJ, Masubuchi T, Hui E, Majzner RG, Garcia KC
Supercharged fluorescent proteins detect lanthanides via direct antennae signaling.
1. Nat Commun - published October 2, 2024
2. Huang KY, Cardenas L, Ellington AD, Walker DJF
Non-canonical amino acids for site-directed spin labeling of membrane proteins.
1. Curr Opin Struct Biol - published October 2, 2024
2. Ledwitch K, Künze G, Okwei E, Sala D, Meiler J
Hyaluronic acid-coated zein nanoparticle-mediated resveratrol therapy for the reduction of cisplatin-associated nephrotoxicity.
1. Biochem Biophys Res Commun - published October 2, 2024
2. Ning Y, Chen P, Shen Z, Liu X, Gu H
Young investigators in parasitology meeting: building foundations and supporting early-career researchers.
1. Trends Parasitol - published October 2, 2024
2. Rijo-Ferreira F, Ho CM, Rosenberg A
Engineered protein subunit COVID19 vaccine is as immunogenic as nanoparticles in mouse and hamster models.
1. Sci Rep - published October 2, 2024
2. Matthews MM, Kim TG, Kim KY, Meshcheryakov V, Iha HA, Tamai M, Sasaki D, Laurino P, Toledo-Patiño S, Collins M, Hsieh TY, Shibata S, Shibata N, Obata F, Fujii J, Ito T, Ito H, Ishikawa H, Wolf M
Global cellular proteo-lipidomic profiling of diverse lysosomal storage disease mutants using nMOST.
1. bioRxiv - published October 2, 2024
2. Kraus F, He Y, Swarup S, Overmyer KA, Jiang Y, Brenner J, Capitanio C, Bieber A, Jen A, Nightingale NM, Anderson BJ, Lee C, Paulo JA, Smith IR, Plitzko JM, Gygi SP, Schulman BA, Wilfling F, Coon JJ, Harper JW
The CRISPR-associated adenosine deaminase Cad1 converts ATP to ITP to provide antiviral immunity.
1. Cell - published October 2, 2024
2. Baca CF, Majumder P, Hickling JH, Ye L, Teplova M, Brady SF, Patel DJ, Marraffini LA
Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques.
1. Cell - published October 2, 2024
2. Wang H, Cheng C, Dal Santo JL, Shen CH, Bylund T, Henry AR, Howe CA, Hwang J, Morano NC, Morris DJ, Pletnev S, Roark RS, Zhou T, Hansen BT, Hoyt FH, Johnston TS, Wang S, Zhang B, Ambrozak DR, Becker JE, Bender MF, Changela A, Chaudhary R, Corcoran M, Corrigan AR, Foulds KE, Guo Y, Lee M, Li Y, Lin BC, Liu T, Louder MK, Mandolesi M, Mason RD, McKee K, Nair V, O'Dell S, Olia AS, Ou L, Pegu A, Raju N, Rawi R, Roberts-Torres J, Sarfo EK, Sastry M, Schaub AJ, Schmidt SD, Schramm CA, Schwartz CL, Smith SC, Stephens T, Stuckey J, Teng IT, Todd JP, Tsybovsky Y, Van Wazer DJ, Wang S, Doria-Rose NA, Fischer ER, Georgiev IS, Karlsson Hedestam GB, Sheng Z, Woodward RA, Douek DC, Koup RA, Pierson TC, Shapiro L, Shaw GM, Mascola JR, Kwong PD
Dynamic sampling of a surveillance state enables DNA proofreading by Cas9.
1. Cell Chem Biol - published October 2, 2024
2. De Paula VS, Dubey A, Arthanari H, Sgourakis NG
Dissecting the Membrane Association Mechanism of Aerolysin Pores at Femtomolar Concentrations Using Water as a Probe.
1. Nano Lett - published October 2, 2024
2. Roesel T, Cao C, Bada Juarez JF, Dal Peraro M, Roke S
Structural and biophysical characterisation of ubiquitin variants that inhibit the ubiquitin conjugating enzyme Ube2d2.
1. FEBS J - published October 2, 2024
2. McAlpine JMRB, Zhu G, Pudjihartono N, Teyra J, Currie MJ, Tillett ZD, Dobson RCJ, Sidhu SS, Day CL, Middleton AJ
IRGQ-mediated autophagy in MHC class I quality control promotes tumor immune evasion.
1. Cell - published October 2, 2024
2. Herhaus L, Gestal-Mato U, Eapen VV, Mačinković I, Bailey HJ, Prieto-Garcia C, Misra M, Jacomin AC, Ammanath AV, Bagarić I, Michaelis J, Vollrath J, Bhaskara RM, Bündgen G, Covarrubias-Pinto A, Husnjak K, Zöller J, Gikandi A, Ribičić S, Bopp T, van der Heden van Noort GJ, Langer JD, Weigert A, Harper JW, Mancias JD, Dikic I
A nanobody toolbox for recognizing distinct epitopes on Cas9.
1. J Mol Biol - published October 2, 2024
2. Boylan J, Shrem RA, Vallecillo-Viejo IC, Duvall CL, Wadzinski BE, Spiller BW
Ovarian cancer-derived IL-4 promotes immunotherapy resistance.
1. Cell - published October 2, 2024
2. Mollaoglu G, Tepper A, Falcomatà C, Potak HT, Pia L, Amabile A, Mateus-Tique J, Rabinovich N, Park MD, LaMarche NM, Brody R, Browning L, Lin JR, Zamarin D, Sorger PK, Santagata S, Merad M, Baccarini A, Brown BD
Binding Mode of Cyclic Chemerin-9 Peptide and ChemerinS157 Protein at CMKLR1.
1. Chembiochem - published October 1, 2024
2. Schermeng T, Liessmann F, Katharina Ambrosius C, Meiler J, Beck-Sickinger AG
Initiation of ERAD by the bifunctional complex of Mnl1 mannosidase and protein disulfide isomerase.
1. bioRxiv - published October 1, 2024
2. Zhao D, Wu X, Rapoport TA
Two conserved arginine residues facilitate C-S bond cleavage and persulfide transfer in Suf family cysteine desulfurases.
1. bioRxiv - published October 1, 2024
2. Gogar RK, Conte JV, Dunkle JA, Frantom PA
Mechanistic Studies of Small Molecule Ligands Selective to RNA Single G Bulges.
1. bioRxiv - published October 1, 2024
2. Hegde S, Akhter S, Tang Z, Qi C, Yu C, Lewicka A, Liu Y, Koirala K, Reibarkh M, Battaile KP, Cooper A, Lovell S, Holmstrom ED, Wang X, Piccirilli JA, Gao Q, Miao Y, Wang J
Cryo-electron microscopy reveals a single domain antibody with a unique binding epitope on fibroblast activation protein alpha.
1. bioRxiv - published October 1, 2024
2. Xu Z, Sinha A, Pandya DN, Schnicker NJ, Wadas TJ
Visualizing nucleation, condensation and propagation of β-tubulin folding in chaperonin TRiC.
1. bioRxiv - published October 1, 2024
2. Zhao Y, Schmid MF, Chiu W
Inherited PURA Pathogenic Variant Associated With a Mild Neurodevelopmental Disorder.
1. Neurol Genet - published October 1, 2024
2. Hildebrand MS, Braden RO, Lauretta ML, Kaspi A, Leventer RJ, Anderson M, Goel H, Bahlo M, Scheffer IE, Amor DJ, Janowski R, Niessing D, Morgan AT
Structural analysis and shape-based identification of novel inhibitors targeting the Trypanosoma cruzi proteasome.
1. Int J Biol Macromol - published October 1, 2024
2. Silva GM, Gomes SQ, Lopes CD, de Albuquerque S, de Paula da Silva CHT
Biochemical simulation of mutation synthesis and repair during SARS-CoV-2 RNA polymerization.
1. Virology - published October 1, 2024
2. Oo A, Chen Z, Cao D, Cho YJ, Liang B, Schinazi RF, Kim B
Alternating access of a bacterial homolog of neurotransmitter: sodium symporters determined from AlphaFold2 ensembles and DEER spectroscopy.
1. Proc Natl Acad Sci U S A - published October 1, 2024
2. Schwartz AC, Stein RA, Gil-Iturbe E, Quick M, Mchaourab HS
Structural basis for adhesin secretion by the outer-membrane usher in type 1 pili.
1. Proc Natl Acad Sci U S A - published October 1, 2024
2. Bitter RM, Zimmerman MI, Summers BT, Pinkner JS, Dodson KW, Hultgren SJ, Yuan P
Ternary structure of Plasmodium vivaxN-myristoyltransferase with myristoyl-CoA and inhibitor IMP-0001173.
1. Acta Crystallogr F Struct Biol Commun - published October 1, 2024
2. Bolling C, Mendez A, Taylor S, Makumire S, Reers A, Zigweid R, Subramanian S, Dranow DM, Staker B, Edwards TE, Tate EW, Bell AS, Myler PJ, Asojo OA, Chakafana G
Analysis of EGFR binding hotspots for design of new EGFR inhibitory biologics.
1. Protein Sci - published October 1, 2024
2. Tydings CW, Singh B, Smith AW, Ledwitch KV, Brown BP, Lovly CM, Walker AS, Meiler J
Ligand-induced CaMKIIα hub Trp403 flip, hub domain stacking, and modulation of kinase activity.
1. Protein Sci - published October 1, 2024
2. Narayanan D, Larsen ASG, Gauger SJ, Adafia R, Hammershøi RB, Hamborg L, Bruus-Jensen J, Griem-Krey N, Gee CL, Frølund B, Stratton MM, Kuriyan J, Kastrup JS, Langkilde AE, Wellendorph P, Solbak SMØ
Factors associated with the choice of treatment for coronoid fractures.
1. Bone Joint J - published October 1, 2024
2. de Klerk HH, Verweij LPE, Doornberg JN, Jaarsma RL, Murase T, Chen NC, van den Bekerom MPJ, and the Elbow Injury Management Consortium, and the Elbow Injury Management Consortium (EIMC), Al K, Ar B, Ac W, A VT, Ac AP, A T, A B, B M, B T, B J, Cs M, Cm L, Cg L, Cg T, C R, D R, Ds R, D E, E AG, E K, Et E, Gi B, Jn L, Ja W, J P, J A, K S, K S, Al B, Ms C, M M, Ml R, Mj S, N A, N W, Nwl S, P A, P M, R B, Rj T, R VR, R G, S S, Sd D, S T, T M, Y C
The structural landscape of Microprocessor-mediated processing of pri-let-7 miRNAs.
1. Mol Cell - published October 1, 2024
2. Garg A, Shang R, Cvetanovic T, Lai EC, Joshua-Tor L
The molecular dissection of TRIM25's RNA-binding mechanism provides key insights into its antiviral activity.
1. Nat Commun - published October 1, 2024
2. Álvarez L, Haubrich K, Iselin L, Gillioz L, Ruscica V, Lapouge K, Augsten S, Huppertz I, Choudhury NR, Simon B, Masiewicz P, Lethier M, Cusack S, Rittinger K, Gabel F, Leitner A, Michlewski G, Hentze MW, Allain FHT, Castello A, Hennig J
Next-generation cell-penetrating antibodies for tumor targeting and RAD51 inhibition.
1. Oncotarget - published October 1, 2024
2. Rackear M, Quijano E, Ianniello Z, Colón-Ríos DA, Krysztofiak A, Abdullah R, Liu Y, Rogers FA, Ludwig DL, Dwivedi R, Bleichert F, Glazer PM
Molecular architecture and functional dynamics of the pre-incision complex in nucleotide excision repair.
1. Nat Commun - published October 1, 2024
2. Yu J, Yan C, Paul T, Brewer L, Tsutakawa SE, Tsai CL, Hamdan SM, Tainer JA, Ivanov I
Erratum: Studying Orthodontic Tooth Movement in Mice.
1. J Vis Exp - published October 1, 2024
2. Dukes MJ, Gilmore BL, Tanner JR, McDonald SM, Kelly DF
How bacteria initiate DNA replication comes into focus.
1. Bioessays - published October 1, 2024
2. Rashid F, Berger JM
Structures of the Foamy virus fusion protein reveal an unexpected link with the F protein of paramyxo- and pneumoviruses.
1. Sci Adv - published October 1, 2024
2. Fernández I, Bontems F, Brun D, Coquin Y, Goverde CA, Correia BE, Gessain A, Buseyne F, Rey FA, Backovic M
Enhancing Spectrometer Performance with Unsupervised Machine Learning.
1. J Phys Chem B - published October 1, 2024
2. Harding BD, Hu Z, Hiett A, Delaglio F, Henzler-Wildman KA, Rienstra CM
Native Mass Spectrometry of Membrane Protein-Lipid Interactions in Different Detergent Environments.
1. Anal Chem - published October 1, 2024
2. Kumar S, Stover L, Wang L, Bahramimoghaddam H, Zhou M, Russell DH, Laganowsky A
Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2.
1. Nat Commun - published October 1, 2024
2. Scott DC, Dharuman S, Griffith E, Chai SC, Ronnebaum J, King MT, Tangallapally R, Lee C, Gee CT, Yang L, Li Y, Loudon VC, Lee HW, Ochoada J, Miller DJ, Jayasinghe T, Paulo JA, Elledge SJ, Harper JW, Chen T, Lee RE, Schulman BA
Assessing Military Mental Health during the Pandemic: A Five Country Collaboration.
1. Curr Psychiatry Rep - published October 1, 2024
2. Lee JEC, Bennett C, Bennett N, Bouak F, Goldenberg I, Harrison K, Edge HM, Bell AM, Quartana PJ, Simms MA, Adler AB
Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation.
1. Proc Natl Acad Sci U S A - published October 1, 2024
2. Hu Y, Lopez VA, Xu H, Pfister JP, Song B, Servage KA, Sakurai M, Jones BT, Mendell JT, Wang T, Wu J, Lambowitz AM, Tomchick DR, Pawłowski K, Tagliabracci VS
Fluorescent and bioluminescent bovine H5N1 influenza viruses for evaluation of antiviral interventions.
1. J Virol - published October 1, 2024
2. Trimarco JD, Spurrier MA, Skavicus S, Luo Z, Dutta M, Janowska K, Acharya P, Heaton BE, Heaton NS
Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons.
1. Nat Biotechnol - published October 1, 2024
2. Hergenreder E, Minotti AP, Zorina Y, Oberst P, Zhao Z, Munguba H, Calder EL, Baggiolini A, Walsh RM, Liston C, Levitz J, Garippa R, Chen S, Ciceri G, Studer L
TRPML1 gating modulation by allosteric mutations and lipids.
1. Elife - published October 1, 2024
2. Gan N, Han Y, Zeng W, Jiang Y
Characterization of conformational states of the homodimeric enzyme fluoroacetate dehalogenase by (19)F-(13)C two-dimensional NMR.
1. RSC Chem Biol - published October 1, 2024
2. Suleiman M, Frere GA, Törner R, Tabunar L, Bhole GV, Taverner K, Tsuchimura N, Pichugin D, Lichtenecker RJ, Vozny O, Gunning P, Arthanari H, Sljoka A, Prosser RS
GoToCloud optimization of cloud computing environment for accelerating cryo-EM structure-based drug design.
1. Commun Biol - published October 1, 2024
2. Moriya T, Yamada Y, Yamamoto M, Senda T
Molecular basis of cell membrane adaptation in daptomycin-resistant Enterococcus faecalis.
1. JCI Insight - published October 1, 2024
2. Nguyen AH, Tran TT, Panesso D, Hood KS, Polamraju V, Zhang R, Khan A, Miller WR, Mileykovskaya E, Shamoo Y, Xu L, Vitrac H, Arias CA
Advances and challenges in RAS signaling targeted therapy in leukemia.
1. Mol Cancer Ther - published October 1, 2024
2. Chen Y, Yin Z, Westover KD, Zhou Z, Shu L
Total Synthesis and Structural Reassignment of the Antitubercular Natural Product Evybactin.
1. Chemistry - published October 1, 2024
2. Lysenko V, Son S, Theriault ME, Slingerland CJ, Hauk G, Cleenewerk L, Speer A, Berger JM, Lewis K, Martin N
Molecular basis for the transcriptional regulation of an epoxide-based virulence circuit in Pseudomonas aeruginosa.
1. Nucleic Acids Res - published October 1, 2024
2. He S, Taher NM, Simard AR, Hvorecny KL, Ragusa MJ, Bahl CD, Hickman AB, Dyda F, Madden DR
Chikungunya virus E2 B domain nanoparticle immunogen elicits homotypic neutralizing antibody in mice.
1. Vaccine - published October 1, 2024
2. Tong K, Hernandez EM, Basore K, Fremont DH, Lai JR
Mechanism of bacterial predation via ixotrophy.
1. Science - published October 1, 2024
2. Lien YW, Amendola D, Lee KS, Bartlau N, Xu J, Furusawa G, Polz MF, Stocker R, Weiss GL, Pilhofer M
Notch induces transcription by stimulating release of paused RNA polymerase II.
1. Genes Dev - published October 1, 2024
2. Rogers JM, Mimoso CA, Martin BJE, Martin AP, Aster JC, Adelman K, Blacklow SC
SARS-CoV-2 ferritin nanoparticle vaccines produce hyperimmune equine sera with broad sarbecovirus activity.
1. iScience - published October 1, 2024
2. Martinez EJ, Chang WC, Chen WH, Hajduczki A, Thomas PV, Jensen JL, Choe M, Sankhala RS, Peterson CE, Rees PA, Kimner J, Soman S, Kuklis C, Mendez-Rivera L, Dussupt V, King J, Corbett C, Mayer SV, Fernandes A, Murzello K, Cookenham T, Hvizdos J, Kummer L, Hart T, Lanzer K, Gambacurta J, Reagan M, Duso D, Vasan S, Collins ND, Michael NL, Krebs SJ, Gromowski GD, Modjarrad K, Kaundinya J, Joyce MG
MPXV Infection Stimulates a More Robust and Durable Neutralizing Antibody Response Compared to MVA-BN Vaccination.
1. J Infect Dis - published October 1, 2024
2. Selverian CN, Monticelli SR, Jaleta YM, Lasso G, DeMouth ME, Meola A, Berrigan J, Batchelor TG, Battini L, Guardado-Calvo P, Herbert AS, Chandran K, Meyerowitz E, Miller EH
An ILC2-chitinase circuit restores lung homeostasis after epithelial injury.
1. Sci Immunol - published October 1, 2024
2. Jung H, Kim DH, Díaz RE, White JM, Rucknagel S, Mosby L, Wang Y, Reddy S, Winkler ES, Hassan AO, Ying B, Diamond MS, Locksley RM, Fraser JS, Van Dyken SJ
A flagellar accessory protein links chemotaxis to surface sensing.
1. J Bacteriol - published October 1, 2024
2. Salemi RI, Cruz AK, Hershey DM
A conserved fertilization complex bridges sperm and egg in vertebrates.
1. Cell - published October 1, 2024
2. Deneke VE, Blaha A, Lu Y, Suwita JP, Draper JM, Phan CS, Panser K, Schleiffer A, Jacob L, Humer T, Stejskal K, Krssakova G, Roitinger E, Handler D, Kamoshita M, Vance TDR, Wang X, Surm JM, Moran Y, Lee JE, Ikawa M, Pauli A
The homeodomain regulates stable DNA binding of prostate cancer target ONECUT2.
1. Nat Commun - published October 1, 2024
2. Chatterjee A, Gallent B, Katiki M, Qian C, Harter MR, Silletti S, Komives EA, Freeman MR, Murali R
Qingshen granules inhibits dendritic cell glycolipid metabolism to alleviate renal fibrosis via PI3K-AKT-mTOR pathway.
1. Phytomedicine - published October 1, 2024
2. Zhou WJ, Liang W, Hu MX, Ma YK, Yu S, Jin C, Li JQ, Wang C, Wang CZ, Gong P, Wu QQ, Wu CG, Wang YP, Liu TT
Phosphorylation regulates the chromatin remodeler SMARCAD1 in nucleosome binding, ATP hydrolysis, and histone exchange.
1. J Biol Chem - published October 1, 2024
2. Aboulache BL, Hoitsma NM, Luger K
Comprehensive functional evaluation of head and neck squamous cell carcinoma with BH3-profiling demonstrates apoptotic competency and therapeutic efficacy of BH3-mimetics.
1. Oral Oncol - published October 1, 2024
2. Li D, Lopez A, Shrivastava N, Chan W, Thomas C, Burk R, Segall J, Augustine S, Rosenblatt G, Mehta V, Schiff BA, Smith RV, Prystowsky MB, Schlecht NF, Guha C, Gavathiotis E, Ow TJ
Structural insights into the DNA-binding mechanism of BCL11A: The integral role of ZnF6.
1. Structure - published October 1, 2024
2. Viennet T, Yin M, Jayaraj A, Kim W, Sun ZJ, Fujiwara Y, Zhang K, Seruggia D, Seo HS, Dhe-Paganon S, Orkin SH, Arthanari H
Determination of Protein-Ligand Binding Affinities by Thermal Shift Assay.
1. ACS Pharmacol Transl Sci - published October 1, 2024
2. Khan MF, Rahman MM, Xin Y, Mustafa A, Smith BJ, Ottemann KM, Roujeinikova A
Molecular mechanism of a triazole-containing inhibitor of Mycobacterium tuberculosis DNA gyrase.
1. iScience - published October 1, 2024
2. Gedeon A, Yab E, Dinut A, Sadowski E, Capton E, Dreneau A, Petit J, Gioia B, Piveteau C, Djaout K, Lecat E, Wehenkel AM, Gubellini F, Mechaly A, Alzari PM, Deprez B, Baulard A, Aubry A, Willand N, Petrella S
Nanobodies: from high-throughput identification to therapeutic development.
1. Mol Cell Proteomics - published October 1, 2024
2. Fridy PC, Rout MP, Ketaren NE
Quinoline-based compounds can inhibit diverse enzymes that act on DNA.
1. Cell Chem Biol - published October 1, 2024
2. Zhou J, Chen Q, Ren R, Yang J, Liu B, Horton JR, Chang C, Li C, Maksoud L, Yang Y, Rotili D, Jain AK, Zhang X, Blumenthal RM, Chen T, Gao Y, Valente S, Mai A, Cheng X
The Role of General Acid Catalysis in the Mechanism of an Alkyl Transferase Ribozyme.
1. ACS Catal - published October 1, 2024
2. Wilson TJ, McCarthy E, Ekesan Ş, Giese TJ, Li NS, Huang L, Piccirilli JA, York DM, Lilley DMJ
2.6-Å resolution cryo-EM structure of a class Ia ribonucleotide reductase trapped with mechanism-based inhibitor N(3)CDP.
1. bioRxiv - published October 1, 2024
2. Westmoreland DE, Feliciano PR, Kang G, Cui C, Kim A, Stubbe J, Nocera DG, Drennan CL
Identification of functional rare coding variants in IGF-1 gene in humans with exceptional longevity.
1. bioRxiv - published October 1, 2024
2. Ali A, Zhang Z, Gao T, Aleksic S, Gavathiotis E, Barzilai N, Milman S
Bond-centric modular design of protein assemblies.
1. bioRxiv - published October 1, 2024
2. Wang S, Favor A, Kibler R, Lubner J, Borst AJ, Coudray N, Redler RL, Chiang HT, Sheffler W, Hsia Y, Li Z, Ekiert DC, Bhabha G, Pozzo LD, Baker D
Distinct roles of size-defined HDL subpopulations in cardiovascular disease.
1. Curr Opin Lipidol - published October 1, 2024
2. Davidson WS, Vaisar T, Heinecke JW, Bornfeldt KE
Characterization of neural infection by Oropouche orthobunyavirus.
1. bioRxiv - published October 1, 2024
2. Connors KA, Pedlow MR, Frey ZD, McGaughey JJ, Amarasinghe GK, Duprex WP, D'Aiuto L, Wills ZP, Hartman AL
In situ crystalline structure of the human eosinophil major basic protein-1.
1. bioRxiv - published October 1, 2024
2. Yang JE, Mitchell JM, Bingman CA, Mosher DF, Wright ER
An approach for coherent periodogram averaging of tilt-series data for improved CTF estimation.
1. bioRxiv - published October 1, 2024
2. Khavnekar S, Wan W
Systematic, high-throughput characterization of bacteriophage gene essentiality on diverse hosts.
1. bioRxiv - published October 1, 2024
2. Chen J, Nilsen ED, Chitboonthavisuk C, Mo CY, Raman S
Association of COVID-19 risk factors with systemic fungal infections in hospitalized patients.
1. medRxiv - published October 1, 2024
2. Wilbourn AC, Tsodikov OV, Garneau-Tsodikova S
ExoSloNano: Multi-Modal Nanogold Tags for identification of Macromolecules in Live Cells & Cryo-Electron Tomograms.
1. bioRxiv - published October 1, 2024
2. Young LN, Sherrard A, Zhou H, Shaikh F, Hutchings J, Riggi M, Rosen MK, Giraldez AJ, Villa E