Supported Operating Systems

The SBGrid Software Suite can run on computers running Linux and macOS/OS X operating systems.


We build and test software under 64-bit CentOS 7, AlmaLinux/Rocky 8, and AlmaLinux/Rocky 9. The majority of our Linux users are using Red Hat or CentOS/Alma/Rocky distributions, but labs also use Ubuntu, Debian and OpenSuSE with SBGrid. We don't explicitly test the software on distributions other than the RHEL-based distros above, but the majority of the software is known to work. We will work to resolve problems reported by users of these Linux distributions where possible on a best-effort basis.

We officially support the three most recent releases of Red Hat/CentOS/Scientific Linux (currently 7, 8 and 9).

  • Red Hat Enterprise Linux 7.x, 8.x, 9.x and their community supported versions: CentOS, AlmaLinux, Rocky Linux, Oracle Linux and Scientific Linux. Amazon Linux 2 is also supported.
  • We are no longer building software for RHEL/CentOS 5.x or 6.x.

GPUs We support a number of titles that run on nVidia GPU hardware. We include the required libraries for these applications and typically only the latest driver for the hardware is required.

OS X / macOS

We build and test programs for macOS under the most five most recent OS X/macOS releases.

Currently Supported:

  • OS X 10.14 - macOS 13
  • As above with earlier versions of linux, there are many software applications that are fully functional on earlier versions of MacOSX in the SBGrid tree. We work to maintain an environment compatible with these OS versions, though they may not receive the latest applications.
  • "Apple Silicon" macs can run most of the software in the collection. Few native applications are currently available, but most 64-bit software works through Apple's Rosetta2 compatility environment. Notable exceptions are applications compiled with Intel compilers (some older Rosetta and RELION verions).

Windows Intel

Windows provides Linux compatibility environment called "Windows Subsystem for Linux" (WSL), based on Ubuntu. WSL is still under active development. We suspect it is possible to get the SBGrid applications working with WSL, but we have no experience with Windows can can't provide support. If you have success with SBGrid and WSL, let us know.

OS X PowerPC

The OS X PowerPC branch is currently frozen and is obsolete. The applications are archived and available on request.


The IRIX programs branch is currently frozen and is obsolete. The applications are archived and available on request. SGI was fun.