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TomoDRGN

  • Description

    extends the cryoDRGN framework to cryo-ET by learning heterogeneity from datasets in which each particle is sampled by multiple projection images at different stage tilt angles.

  • Usage

    To list all executables provided by TomoDRGN, run: $ sbgrid-list tomodrgn Copy to clipboard

  • Installation

    Use the following command to install this title with the CLI client: $ sbgrid-cli install tomodrgn Copy to clipboard Available operating systems: Linux 64

  • Primary Citation*

    B. M. Powell and J. H. Davis. 2023. Learning structural heterogeneity from cryo-electron sub-tomograms with tomoDRGN. BioRXiv.


    • *Full citation information available through

  • Webinars

    TomoDRGN - Visualizing molecular machines in motion through cryoET and deep learning

    SBGrid webinars are hosted with partial support from the NIH R25 Continuing Education for Structural Biology Mentors #GM151273, in collaboration with Co-PI Jamaine Davis of Meharry Medical College.

    Topic: TomoDRGN - Visualizing molecular machines in motion through cryoET and deep learning

    Presenter: Professor Joseph Davis, Department of Biology, MIT

    Host: Jason Key
    Recorded on June 11, 2024

    For more information on TomoDRGN:

    https://sbgrid.org/software/titles/tomodrgn
    https://github.com/ml-struct-bio/cryodrgn
    https://github.com/bpowell122/tomoDRGN
    https://github.com/lkinman/MAVEn

  • Keywords

    Electron Microscopy

  • Default Versions

    Linux 64:  0.2.2 (5.4 GB)

  • Developers

    Barrett Powell, Joseph Davis

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