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  • Description

    (Single-particle IMage Processing Linux Engine) does ab initio 3D reconstruction (programs cluster & origami), heterogeneity analysis (programs cluster, origami & cycler), and high-resolution refinement (programs align, reconstruct, automask & cycler).

  • Usage

    To list all executables provided by SIMPLE, run: $ sbgrid-list simple Copy to clipboard
  • Usage Notes

    The SIMPLE back-end consists of an object-oriented numerical library with a single external dependency - the Fastest Fourier Transform in the West (FFTW). The SIMPLE front-end consists of a few standalone, interoperable components developed according to the 'Unix toolkit philosophy'.

  • Installation

    Use the following command to install this title with the CLI client: $ sbgrid-cli install simple Copy to clipboard Available operating systems: Linux 64, OS X INTEL
  • Primary Citation*

    D. Elmlund and H. Elmlund. 2012. SIMPLE: Software for ab initio reconstruction of heterogeneous single-particles. J Struct Biol. 180(3): 420-427.

    • *Full citation information available through

  • Keywords

    Electron Microscopy

  • Default Versions

    Linux 64:  3.0 (1.5 GB)
    OS X INTEL:  3.0 (1.7 GB)

  • Other Versions

      Linux 64:

      2.1 (89.1 MB) , 2.5 (24.8 MB)
    • OS X INTEL:

      2.1 (204.5 MB) , 2.5 (25.2 MB)
  • Developers

    Hans Elmlund, Dominika Elmlund, Michael Eager, Cyril Reboul