Supported Applications

RosettaDDGPrediction

Description

is a Python package to run Rosetta-based protocols for the prediction of the ΔΔG of stability upon mutation of a monomeric protein or the ΔΔG of binding upon mutation of a protein complex and analyze the results.
Usage
To list all executables provided by RosettaDDGPrediction, run: $ sbgrid-list rosettaddgprediction
Installation
Use the following command to install this title with the CLI client: $ sbgrid-cli install rosettaddgprediction Available operating systems: Linux 64, OS X INTEL
Citation Note

RosettaDDGPrediction for high-throughput mutational scans: from stability to binding
Valentina Sora, Adrian Otamendi Laspiur, Kristine Degn, Matteo Arnaudi, Mattia Utichi, Ludovica Beltrame, Dayana De Menezes, Matteo Orlandi, Olga Rigina, Peter Wad Sackett, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo* under revision for Protein Science and on biorxiv: https://doi.org/10.1101/2022.09.02.506350

Keywords

Bioinformatics, Computational Chemistry
Default Versions

Linux 64: 20250408 (565.1 MB)
OS X INTEL: 20250408 (524.6 MB)
Developers

Matteo Tiberti, Elena Papaleo