Search
Bluesky

SBGridTV
Button for mobile navigation
Join us

Supported Applications

RFdiffusion2

  • Description

    is an atom-level enzyme active site scaffolding tool that generates protein backbones conditioned on atomic motifs and small molecules. The software supports enzyme design from atomic motifs with unknown sequence positions, small-molecule binder design with RASA conditioning, and includes integration with LigandMPNN for sequence fitting and Chai1 for structure validation. It provides both indexed backbone and unindexed atomized region outputs with optional idealization steps for enhanced structural quality.

  • Usage

    To list all executables provided by RFdiffusion2, run: $ sbgrid-list rfdiffusion2 Copy to clipboard

  • Installation

    Use the following command to install this title with the CLI client: $ sbgrid-cli install rfdiffusion2 Copy to clipboard Available operating systems: Linux 64
Scroll