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REPIC

  • Description

    REliable PIcking by Consensus (REPIC) is a consensus methodology for harnessing multiple cryogenic-electron microscopy (cryo-EM) particle picking algorithms. It identifies particles common to multiple picked particle sets (i.e., consensus particles) using graph theory and integer linear programming (ILP). Picked particle sets may be found by a human specialist (manual), template matching, mathematical function (e.g., RELION's Laplacian-of-Gaussian auto-picking), or machine-learning method.

  • Usage

    To list all executables provided by REPIC, run: $ sbgrid-list repic Copy to clipboard

  • Installation

    Use the following command to install this title with the CLI client: $ sbgrid-cli install repic Copy to clipboard Available operating systems: Linux 64

  • Primary Citation*

    C. J. F. Cameron, S. J. H. Seager, F. J. Sigworth, H. D. Tagare, and M. B. Gerstein. 2024. REliable PIcking by Consensus (REPIC): a consensus methodology for harnessing multiple cryo-EM particle pickers. Communications biology. 7(1): 1421.


    • *Full citation information available through

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