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SBGridTV

Supported Applications

MODELLER

  • Description

    used for homology or comparative modeling of protein three-dimensional structures. The user provides an alignment of a sequence to be modeled with known related structures and MODELLER automatically calculates a model containing all non-hydrogen atoms. MODELLER implements comparative protein structure modeling by satisfaction of spatial restraints, and can perform many additional tasks, including de novo modeling of loops in protein structures, optimization of various models of protein structure with respect to a flexibly defined objective function, multiple alignment of protein sequences and/or structures, clustering, searching of sequence databases, comparison of protein structures, etc. A graphical interface to MODELLER is commercially available from Accelrys, as part of Discovery Studio Modeling 1.1.

  • Usage Notes

    No graphical interface. To start the program type 'modeller'. There are some tutorials to get you started available at http://salilab.org/modeller/tutorial/.

  • Primary Citation*

    A. Sali and T. Blundell. 1993. Comparative protein modelling by satisfaction of spatial restraints. J Mol Biol. 234(3): 779-815.

    • *Full citation information available through

  • Categories

    Computational Chemistry

  • Default Versions

    Linux 64 9.16
    OS X INTEL 9.16

  • Other Available Versions

    Linux 32 9.10
    Linux 32 9.11
    Linux 32 9.12
    Linux 32 9.9
    Linux 64 9.14
    Linux 64 9.15
    OS X INTEL 9.14
    OS X INTEL 9.15
    powermac 8v1
    powermac 9v4
    powermac 9v7
    powermac 9v8
    powermac 9v9

  • Developers

    Andrej Sali, Ben Webb.