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DiffModeler

  • Description

    a computational tool using a diffusion model to automatically build full protein complex structure from cryo-EM maps at 0-20A resolution.

  • Usage

    To list all executables provided by DiffModeler, run: $ sbgrid-list diffmodeler Copy to clipboard

  • Installation

    Use the following command to install this title with the CLI client: $ sbgrid-cli install diffmodeler Copy to clipboard Available operating systems: Linux 64

  • Primary Citation*

    X. Wang, H. Zhu, G. Terashi, M. Taluja, and &. D. Kihara. 2024. DiffModeler: large macromolecular structure modeling for cryo-EM maps using a diffusion model. Nature Methods. 2307-2317.


    • *Full citation information available through

  • Webinars

    DiffModeler & CryoREAD

    SBGrid webinars are hosted with partial support from the NIH R25 Continuing Education for Structural Biology Mentors #GM151273, in collaboration with Co-PI Jamaine Davis of Belmont University.

    Topic:
    DiffModeler & CryoREAD: Macromolecular and Nucleic Acid Structure Modeling for Cryo-EM Maps Using Deep Learning

    Presenter: Genki Terashi, Ph.D. Assistant Research Scientist, Daisuke Kihara's Laboratory, Purdue University

    Host: Jason Key
    Recorded on June 10, 2025

    For more information on DiffModeler & CryoREAD:
    https://sbgrid.org/software/titles/diffmodeler
    https://sbgrid.org/software/titles/cryoread

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