Member Publications

Jump to specific year:

116 Member Publications for September

Previous Month

Architecture of a DNA-guided Cas12a.
1. Nat Struct Mol Biol - published September 9, 2026
2. Ocampo RF, Orosco C, Huang B, West MS, Parker B, Jain PK, Taylor DW
Establishment of an efficient Agrobacterium-mediated genetic transformation protocol for Saccharum officinarum using Black Cheribon as a model genotype.
1. Front Plant Sci - published September 9, 2026
2. Li C, Li X, Tian C, Hu X, Lu X, Nawaz G, Yang T, Liu X, Zhang Y
Leukocyte immunoglobulin-like receptor A3 inhibits the activity of immunosuppressive myeloid cells.
1. Cancer Immunol Res - published September 9, 2026
2. Fang M, Yang X, Xie J, Lou Q, Zhang C, Huang R, Liu X, He Y, Khan AEMA, Lewis CM, Zhang CC
O-mannosylation and protein maturation checkpoints represent therapeutic opportunities in BRAF fusion protein oncogenesis.
1. Cancer Discov - published September 9, 2026
2. Borgenvik A, Misek SA, Christen D, Kyrila G, Zhang A, Reel S, Boisvert M, Cai KY, Kovarzin A, Li H, Zhou KN, Gonzalez EM, Buch-Larsen SC, Hendriks IA, Olsen JV, Anastasaki C, Xu E, Goodale A, Lazo de la Vega L, Ragnoni TJ, Kalani Z, Persky NS, Abid T, Miglietta EA, Vakhrushev SY, Stumpe M, Jones JS, Malinowski S, Elsadek LA, Parikh J, Condurat AL, Fultineer A, Choi SH, Ozdemir M, Eisenbies Z, Lee J, Novikov D, Bahadur S, Apfelbaum AA, Robinson J, Clark LM, Schulman N, Lopez G, Kocher D, Ortiz-Cordero C, Tang K, Maldera A, Bondeson DP, Kwon JJ, Vallurupalli M, Jeon H, Pal S, Jacobs S, Golub TR, Hahn WC, De Smet F, Sigaud R, Fischer ES, Boehm JS, Dengjel J, Clausen H, Jabado N, Milde T, Carpenter AE, Gutmann DH, Cimini BA, Ligon KL, Janeway KA, Eck MJ, Parker Kerrigan BC, Root DE, Jones DTW, Sharifnia T, Phoenix TN, Beroukhim R, Joshi HJ, Brummer T, Halim A, Bandopadhayay P
Structural mechanisms for ATP-mediated inhibition of human NLRP6 inflammasome.
1. Nat Struct Mol Biol - published September 8, 2026
2. Cui Z, Sheng Q, Son M, Goo YA, Shen C
Structural basis of a SWI/SNF-associated transcription pre-initiation complex.
1. Cell - published September 8, 2026
2. Nagai S, Yang C, Chen DH, Trnka MJ, Bushnell DA, Burlingame AL, Murakami K, Kornberg RD
Catalytic properties of the integral membrane RAS protease Rce1.
1. J Biol Chem - published September 8, 2026
2. van Dongen DJ, Collette AM, Diver MM, Long SB
Structural and regulatory features associated with elevated accumulation of the rice ERFVII transcription factor SUB1A-1.
1. J Exp Bot - published September 8, 2026
2. Ho MC, Lin CS, Shih MC, Lin CC
Fission yeast RPA-TERT-Tpz1TPP1 complex promotes telomere extension and suppresses telomere recombination.
1. PLoS Genet - published September 8, 2026
2. Moser BA, Points M, Agrawal S, Didier AC, Mennie AK, Lim CJ, Xu YJ, Nakamura TM
Structure-based design of soluble prefusion-stabilized herpes simplex virus type 2 glycoprotein B antigens.
1. Cell Rep - published September 8, 2026
2. Sponholtz MR, Ma DY, Ndashimye E, Byrne PO, Shu Y, Warren C, Thambi N, McCool RS, Slein MD, Johnson NV, Rose WA 2nd, Zhang L, Durr E, Wang D, McLellan JS
Importance of the gonococcal MtrCDE efflux pump system in decreasing bacterial susceptibility to zoliflodacin: implications for future clinical treatment of gonorrhea.
1. mBio - published September 8, 2026
2. Balthazar JT, Holley CL, Dey D, Conn GL, Shafer WM
Mechanism of gating and isoform-specific inhibition in renal CLC chloride channels.
1. Proc Natl Acad Sci U S A - published September 8, 2026
2. Chien CT, Sobecks-Doherty BL, Powers AS, Das A, Kreiter J, Barry CN, Chen M, Hinman A, Petrakian CF, Williams B, Wood CAP, Xu M, Dror RO, Chiu W, Maduke M
Molecular basis of tRNA substrate recognition and modification by the atypical SPOUT methyltransferase Trm10.
1. Nucleic Acids Res - published September 7, 2026
2. Nandi S, Strassler SE, Dey D, Whitney CB, Roumaya OB, Krishnamohan A, Harris GM, Comstock LR, Jackman JE, Conn GL
Deadenylation and decapping factors cooperatively stimulate biochemical activities of DEAD-box ATPase Dhh1.
1. Nucleic Acids Res - published September 7, 2026
2. Braun GA, Kumar R, Hinnebusch AG, Gross JD
Conserved mRNP remodeling mechanism of the TREX-2.1 complex.
1. Nucleic Acids Res - published September 7, 2026
2. Angelos AE, Asada R, Clarke BP, Hill PS, Li L, Mei M, Smith JL, Xie ER, Reter WC, Smithee SJ, Xie Y, Montpetit B, Ren Y
An expanded realm of anti-CRISPR-associated proteins and regulatory mechanisms.
1. Nucleic Acids Res - published September 7, 2026
2. Feussner M, Birkholz N, Lee SY, Beisel CL, Park HH, Brown CM, Fineran PC, Weinberg Z
Heme as a Versatile Signaling Molecule: Coordinating Mitochondrial Metabolism with Global Cellular Responses.
1. J Biol Chem - published September 7, 2026
2. Chitrakar I, Brown BL
Interdependent RNA structural motifs at the 3'-terminus of the West Nile virus genome regulate viral growth.
1. Nucleic Acids Res - published September 7, 2026
2. Tsao LH, Brackney DE, Pyle AM
Receptor-tethered orthogonal IL-2 enhances regulatory T cell therapy.
1. J Exp Med - published September 7, 2026
2. Indart AC, Lyu H, Nguyen VQ, Rosenthal W, Palvai JR, Jang SS, Chen Y, Jude K, Su L, Garcia KC, Bluestone JA, Tang Q
Newborn screening reduces survival disparities in SCID after stem cell transplant: A PIDTC report.
1. J Hum Immun - published September 7, 2026
2. Winestone LE, Logan BR, Liu X, Williams O, Dunn EA, Thakar MS, Kidd SA, Mousallem T, Dorsey MJ, O'Reilly RJ, Kapoor N, Forbes Satter L, Kapadia M, Jyonouchi SC, Chandra S, Ebens CL, Chellapandian D, Chaudhury S, Chen K, Dávila Saldaña BJ, Rayes A, Quigg TC, Chandrakasan S, Bednarski JJ, DeSantes KB, Teira P, Gillio AP, Eissa H, Knutsen AP, Aquino VM, Shereck EB, Moore TB, Caywood EH, Vander Lugt MT, Rozmus J, Broglie L, Yu LC, Shah AJ, Joshi AY, Buckley RH, Dara J, Oved JH, Abdel Azim H, Martinez CA, Prockop S, Sullivan KE, Bleesing JJ, Keller MD, Madden LM, Parikh S, Shenoy S, Seroogy CM, Rubin T, Licata J, Andolina JR, Kohn DB, Burroughs L, Leiding JW, Marsh RA, Notarangelo LD, Pai SY, Torgerson TR, Pulsipher MA, Heimall J, Cuvelier GDE, Griffith LM, Puck JM, Dvorak CC, Cowan MJ, Haddad E
Model prokaryotic potassium channels: Predictive power and relevance to eukaryotic channels.
1. J Gen Physiol - published September 7, 2026
2. Schmidpeter PAM, Nimigean CM
Mechanisms of antibody-mediated enhancement of immune responses.
1. J Exp Med - published September 7, 2026
2. Cipolla M, MacLean AJ, Hernandez B, Silva Santos GS, Stamatatos L, Gazumyan A, Hartweger H, Merkenschlager J, Bournazos S, Ravetch JV, Nussenzweig MC
Overcoming immunogenic gaps in malaria subunit vaccines by broadening CSP regions targeted.
1. J Exp Med - published September 7, 2026
2. Koo JH, Tripathi P, Flores-Garcia Y, Miura K, Bayarsaikhan G, Shen CH, Weldon SR, Kratochvil S, Prum T, Albowaidey AA, Kim YJ, Ellis-Pugh JR, Phan QA, Suurbaar J, Onjiko RS, Choe M, Dale GA, Lei H, Morano NC, Da Silva Pereira L, Dillon M, Bender MF, Lofgren M, Zhang B, Pierson TC, Shapiro L, Zhou T, Nair U, Idris AH, Zavala F, Kwong PD, Seder RA, Batista FD
Racial Disparities in Survival Outcomes for Metastatic Renal Cell Carcinoma with Sarcomatoid Differentiation: A SEER-Based Retrospective Analysis (2010-2020).
1. Cancers (Basel) - published September 6, 2026
2. Meng L, Malone X, Peng H, Mei L, Jiang C, Liu X, Wang QE, Hong F, Sood A, Wang SJ, Wu Q, Wang S, Wang P
Structures of the lipid II flippase from the monoderm pathogen Staphylococcus aureus.
1. J Biol Chem - published September 5, 2026
2. Li YE, Baron GF, Clemons WM Jr
Bacterial AsmA Proteins Transfer Glycerophospholipids Between Membranes in Vitro.
1. Contact (Thousand Oaks) - published September 5, 2026
2. Schilling MA, Reinisch KM
Type IV-C CRISPR-Cas effector complexes recognize double-stranded DNA and switch on collateral cleavage of ssDNA and RNA.
1. Cell Rep - published September 5, 2026
2. Pittman CC, Xu C, Catchpole RJ, Garrett S, Fuchs R, Chu X, Makarova KS, Koonin EV, Zhao P, Wells L, Graveley BR, Ke A, Terns MP
Exploiting DNA damage tolerance for precision oncology.
1. Trends Cancer - published September 5, 2026
2. Bhat A, Lahane GP, Pandita RK, Bacolla A, Hoden B, Ramos KS, Krishnan S, Sarkar PS, Dhar A, Tainer JA, Pandita TK
Ribosomal RNA methylation by GidB modulates discrimination of mischarged tRNA.
1. Elife - published September 4, 2026
2. Bi Z, Chen YX, Young ID, Dandan MT, Joshi H, Su HW, Chen Y, Hong J, Fraser JS, Javid B
Broadly reactive antibodies against influenza B virus hemagglutinin neutralize and protect through distinct structural mechanisms.
1. J Virol - published September 4, 2026
2. Bhavsar D, Civljak A, Bonnettaz B, Arunkumar GA, Krammer F, Bajic G
A designer pore-blocking peptide reveals an electrostatic complementation mechanism for the inhibition-resistant Kv1.5 channel.
1. Sci Adv - published September 4, 2026
2. Zhao R, Nayak M, Shen R, Dai H, Hua P, Perozo E, Goldstein SAN
A Label-Free, Real-Time Impedance-Based Method for High-Throughput Antiviral Screening.
1. J Vis Exp - published September 3, 2026
2. Zolfaghari A, Suryadevara N, Zhang J, Li N, Zhao LL, Crowe JE, Zhang X, Carnahan RH
Bicistronic CD19/CD22 CAR T-Cell Therapy in Pediatric B-Cell Acute Lymphoblastic Leukemia: A Nonrandomized Clinical Trial.
1. JAMA Oncol - published September 3, 2026
2. Wan X, Tang Y, Cai J, Song L, Wang T, Li W, Yang L, Wang X, Luo C, Zhu H, An K, Su M, Zhang J, Yang J, Shi W, Fei C, Shen W, Jia R, Yang X, Tang J, Wu J, Gu J, Mo J, Huang J, Li Y, Zhou G, Ding L, Liang J, Wang J, Zhou Z, Wang X, Cao Q, Zhang J, Ren H, Qian J, Xiao P, He H, Jiang H, Hu S, Wang N, Zhu Y, Tang J, Gu L, Yang J, Cheng C, Chen J, Kuai W, Lu X, Shao J, Xie Z, Lu J, Leung W, Li B, Pui CH
2''F-NAD(+) is a broad-spectrum RNA 2'-phosphotransferase (Tpt1) poison that traps the enzyme on its abortive RNA-2'-phospho-(2''F-ADP-ribose) reaction intermediate.
1. RNA - published September 3, 2026
2. Kasprzyk R, Ghosh S, Shuman S
MOSAIC: A flexible, software-agnostic workflow for montage cryo-ET.
1. Structure - published September 3, 2026
2. Jensen J, Mendonça L
In extracto cryo-EM reveals eEF2 as a major hibernation factor on 60S and 80S particles.
1. Elife - published September 3, 2026
2. Seraj Z, Zottig X, Huang C, Loveland AB, Diggs S, Sholi E, Grigorieff N, Korostelev AA
Early-life colonization with Clostridioides difficile remodels the developing gut.
1. Science - published September 3, 2026
2. Semon A, Manzer HS, Keenan O, Zhou TH, Tiffany C, She Q, Knight M, Weiss AS, Donohoe K, Morrow BT, Glover RC, Kovalik ME, Tanes C, Bittinger K, Zemel BS, Wu GD, Silverman MA, Gerber JS, Cano Rodríguez R, Lacy DB, Karakasheva TA, Alameh MG, Weissman D, Schultz-Cherry SL, Rosch JW, Planet PJ, Moustafa AM, Furth EE, Abt MC, Kelsen JR, Conrad MA, Hamilton KE, Zackular JP
Domain dynamics within the PriA DNA helicase regulate DNA replication restart.
1. Nucleic Acids Res - published September 2, 2026
2. Deorio HR, Duckworth AT, Forsythe GR, Sung AY, Sandler SJ, Grant T, Keck JL
Structural and functional divergence of cancer hotspot mutations in CREBBP.
1. Proc Natl Acad Sci U S A - published September 2, 2026
2. Zhang W, Yang H, Mechaly A, Li Z, Cui G, Regad L, Duval R, Dairou J, Haouz A, Green MR, Rodrigues Lima F
Structural insights into target detection by the Serratia type III CRISPR complex and its deployment in SNP identification.
1. J Biol Chem - published September 2, 2026
2. Perdigao CC, Ajisafe LO, Sunny AT, Wu S, Dokland T, Dunkle JA
De novo design of semisynthetic conduction pores.
1. Nat Struct Mol Biol - published September 2, 2026
2. Schnaider L, Hatstat AK, Scott AJ, Tan SK, Hambley RG, Dawson WM, Griffiths RC, Kormos RC, Melo AA, Tse E, Polizzi NF, Wallace EJ, Merz GE, DeGrado WF
Monovalent cations differentially regulate the activity of eukaryotic fluoride channels and impact fluoride resistance.
1. PLoS Biol - published September 2, 2026
2. Kang CY, Heidari S, Kolb S, An M, Ohi MD, Torabifard H, Stockbridge RB
The teneurin TEN-1 and its ligand LRON-11 support microbiota-induced neuroprotection and mechanosensory function in C. elegans.
1. Curr Biol - published September 2, 2026
2. Li J, Castillo JP, Cheng S, Weathers I, Nawrocka WI, Alvarado J, Zhao M, Calixto A, Özkan E, Araç D
Structural analysis of the primary specificity of thrombin.
1. J Thromb Haemost - published September 2, 2026
2. Friet T, Mikhail G, Mohammed BM, Pelc LA, Dei Rossi A, Korolev S, Di Cera E
The diverse gating mechanisms of bacterial MscS-like ion channels.
1. Biochem Soc Trans - published September 2, 2026
2. Hiotis G, Nakayama Y, Yadav S, Walz T
Cellular adaptations of fission yeast to inositol starvation.
1. mBio - published September 2, 2026
2. Sanchez AM, Babor J, Saoi M, Prucker I, Jessen HJ, Schwer B, Shuman S
Single-cell analysis of StkP activity reveals the temporal dynamics of DivIVA phosphorylation in Streptococcus pneumoniae.
1. mBio - published September 2, 2026
2. Manuse S, Claude L, Alzari PM, Wehenkel AM, Grangeasse C
The structural basis of malodorant skatole formation by the glycyl radical enzyme indoleacetate decarboxylase.
1. Proc Natl Acad Sci U S A - published September 2, 2026
2. Imrich CN, Backman LRF, Allworth AP, Andorfer MC, Paris JC, Greeley NM, Fu B, Balskus EP, Drennan CL
NMR crystallography reveals active-site protonation states of Toho-1 β-lactamase in complex with avibactam.
1. Proc Natl Acad Sci U S A - published September 2, 2026
2. Williams CG, Wang S, Carta V, Langan PS, Thome AF, Ramos SA, Holmes JB, Ghosh RK, Weiss KL, Beran GJO, Hartman JD, Coates L, Rienstra CM, Mueller LJ
Kinetic and Thermodynamic Control of Macrocyclic Peptide Conformation through Late-Stage Chemical Modification.
1. J Am Chem Soc - published September 2, 2026
2. Ou YD, Hur J, Baloh C, Huang B, Kovljenic N, Dudding T, Yudin AK
Creating bottom-up RNA transfer vehicles from synthetic protein assemblies.
1. Nature - published September 2, 2026
2. Schuhmacher MK, Gruber C, Lang CMR, Ruijpers RMW, Mazneykova L, Beinsteiner B, Krus A, Tremmel B, Reinhardt F, Kadletz K, Ma Z, Casalta L, Cambra Bort JM, Otify DY, Balken I, Hetzel L, Merl-Pham J, Dorn T, Luchner M, Bauersachs L, Ganea K, Wieser N, Emrich A, Yağmur E, Rager K, Sagindykova G, Armbrust N, Geilenkeuser J, Westmeyer GG, Becirovic E, Biel M, Istvanffy R, Vogt Weisenhorn DM, Truong DJ, Theis FJ, Ebert G, Moretti A, Ertürk A, Bähr A, Kupatt C, Jasnin M, Klymiuk N, Giesert F, Wurst W
HIV-1 antibody-mediated neutralization via a dual-glycan clamp.
1. Cell Rep - published September 2, 2026
2. Gorman J, Ballard RB, Nazzari AF, O'Dell S, Bylund T, Rawi R, Du R, Nguyen R, Ambrozak D, Zhang B, Du H, Doria-Rose NA, Connors M, Mascola JR, Zhou T, Kwong PD, Roederer M, Mason RD
Structure and operating principles of a monkeypox virus replisome.
1. Nature - published September 2, 2026
2. Yu Z, Sathyanarayana P, Tan JMJ, Hu S, Fan X, Gao A, Kranzusch PJ, Loparo JJ, Abraham J
Functional chimeric mRNAs encode proteins in mammalian immunity.
1. Nature - published September 2, 2026
2. Venezia O, Kane H, Du G, Coughlan HD, Johanson TM, Wang H, Tilstam P, Kazer SW, Gunner G, Hoagland DA, Basavappa MG, Ravichandran K, Ada E, Zhakyp A, Kumar S, Duizer C, Searle O, Provido CG, Joannas L, Yang S, Healy LB, Wang Q, Capocchi J, Dhillon BS, Slavoff S, Shan L, Henao-Mejia J, Franklin RA, Chiu IM, Ordovas-Montanes J, Jeffrey KL, Lieberman J, Allan RS, Kagan JC, Wu H, Jackson R
Multifunctional antibody responses from a primate Shigella outbreak inform vaccine design.
1. Sci Transl Med - published September 2, 2026
2. Gallant RM, Savarino P, Pulido S, Gilman MSA, Lu T, Hayes J, Xerri NL, Williams T, Ochoa MA, Dietz Z, Peterson E, Scott T, Hartmann F, Baker SG, Kaminski RW, Sok D, Kruse AC, Picking W, Capuano SV, Schmidt HR
Multimodal analysis of CD38 in T-cell Acute Lymphoblastic Leukemia Identifies Combinatorial Therapeutic Strategies.
1. Blood - published September 2, 2026
2. Shraim R, Shi G, Li Y, Xu J, Fuller T, Martinez Z, McGrath L, Aplenc R, Cairo MS, Glisovic-Aplenc T, Gill SI, Grupp SA, Hermiston ML, Hogarty MD, Horton T, Hughes AD, June CH, Mullighan CG, Newman H, Pölönen P, Stadtmauer E, Tan K, Tasian SK, Teachey L, Teachey HE, Turn CS, Wang'ondu RW, Wood B, Wertheim G, Teachey DT, Yang JJ, Diorio C
Comparative evaluation of screening approaches for antiviral monoclonal antibody combinations.
1. J Virol - published September 2, 2026
2. McClave MK, Marzi SK, Heldwein EE
Structural organization of TAM receptor ectodomains.
1. Biochem J - published September 2, 2026
2. Starbird CA, Zuo Y, Walker K, Stayrook SE, Ferguson KM
Affinity selection mass spectrometry screening discovers new COP1 peptide binders.
1. RSC Chem Biol - published September 1, 2026
2. Negi H, Radhi N, Schiff N, Jamieson SA, Shea D, Middleditch M, Mullin R, Kowalczyk R, Harris PW, Mace PD, Conole D
Two parallel neural ectoderm progenitors contribute to the developing brain.
1. Nat Neurosci - published September 1, 2026
2. Jokhai RT, Dundes CE, Ahsan HS, Kang RS, Salomon-Shulman REA, Rajan A, Kim YS, Stanton LJ, Xu C, Do S, McDonald BD, Andrade López JM, Urrutia HA, Greenfeld H, Wong A, Qu Y, Petkovic AS, Miao Y, Garcia KC, Monje M, Wagner DE, Bronner ME, Lowe CJ, Loh KM
Editorial Expression of Concern: SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2.
1. Nat Med - published September 1, 2026
2. Kim KH, Kim W, Howard TP, Vazquez F, Tsherniak A, Wu JN, Wang W, Haswell JR, Walensky LD, Hahn WC, Orkin SH, Roberts CWM
Cryo-electron tomography of functionally validated synapses in human induced neurons.
1. Structure - published September 1, 2026
2. Houcek AJ, Sun R, Rothfuss SJ, Chalkley OR, Kavalali ET, Zhou Q
Modulating pseudokinase conformation from the ATP-binding site.
1. Structure - published September 1, 2026
2. Sheetz JB, Tsutsui Y, Ashtekar KD, Mathea S, Knapp S, Lemmon MA
Secreted ORF8 reprograms macrophages to enhance SARS-CoV-2 infection of lung epithelial cells.
1. Sci Adv - published September 1, 2026
2. Matsui Y, Suryawanshi RK, Montano M, Taha TY, Khalid MM, Sun L, Khanna K, Tang J, Zhou Y, Kaake RM, Fang X, Maishan M, Matthay MA, Krogan NJ, Ott M
The intracellular subdomain of the volume-regulated anion channel subunit LRRC8A is a hotspot of channel activation.
1. Nat Commun - published September 1, 2026
2. Bertelli S, Wang L, Klüssendorf M, Gavazzo P, Pusch M, Dutzler R, Stauber T
Ashwin and FAM98 paralogs define nuclear and cytoplasmic RNA ligase complexes for tRNA biogenesis.
1. Nat Commun - published September 1, 2026
2. Kleinwächter M, Moser M, Raynaud N, Pfleiderer MM, Jinek M, Martinez J
Structural framework for the assembly of the human tRNA ligase complex.
1. Nat Commun - published September 1, 2026
2. Pfleiderer MM, Kleinwächter M, Nievergelt AS, Boneberg FM, Kroupova A, Martinez J, Jinek M
GTPase cycle and ER membrane regulate cargo handover during cotranslational protein targeting.
1. Sci Adv - published September 1, 2026
2. Qian R, Gora RJ, Chung S, Lee JH, Chandrasekar S, Wang MF, Weiss S, Shan SO
Prospecting the protein design landscape.
1. FEBS Lett - published September 1, 2026
2. Riccabona JR, Stonig KT, Meiler J, Schoeder CT, Fernández-Quintero ML
Structures of the volume-regulated anion channel LRRC8A/D in activating and inhibiting conditions.
1. Nat Commun - published September 1, 2026
2. Lehmann EF, Stierli F, Rutz S, Deneka D, Dutzler R
Chemoselective halogenation of premarineosin A for next-generation antimalarial development.
1. Org Biomol Chem - published September 1, 2026
2. Harris NR, Amin S, Curtis BJ, Teklemichael AA, Dranchak P, McBride CM, Verhey-Henke L, Warrell CJ, Dulaney WM, Oliphant EN, Inglese J, Su XZ, Sherman DH, Pereira F
Evolution, Mechanisms, and Therapeutic Implications of Mobile Tetracycline Destructases.
1. Bioessays - published September 1, 2026
2. Xue YP, Li R, Gillespie VJ, Yang Z, Tang WK, Tolia NH, Wencewicz TA, Dantas G
Novel far-red fluorescent theranostic probes for selective imaging and targeted therapy of BET proteins in breast cancer.
1. Eur J Med Chem - published September 1, 2026
2. Gao Y, Liu W, Zhang X, Qin L, Liu S, Liu X, Dong G, Liu B, Wang X, Song S, Liu T
Development of a random background to understand ligand optimization.
1. Nature - published September 1, 2026
2. Xu X, Mailhot O, Correy GJ, Huang XP, Braz JM, Shi D, Srinivasan K, Zielinski K, Holota Y, Kuziv Y, Iliopoulos-Tsoutsouvas C, Levinzon ND, Doruk YU, Rachman MM, Diolaiti ME, Stevens MGV, Liu F, Holland KL, Hübner H, Wang J, Wu Y, Ashworth A, Makriyannis A, Zhang Y, Moroz YS, Gmeiner P, Abel R, Manglik A, Basbaum AI, Roth BL, Fraser JS, Shoichet BK
Development and application of nbLIBRA-seq for high-throughput discovery of antigen-specific nanobodies.
1. Cell Rep Methods - published September 1, 2026
2. Leonard S, Wasdin PT, Webb K, Amlashi P, Renken C, Rathmell JC, Spiller BW, Wadzinski BE, Crowe JE, Georgiev IS, Voss K
Transcriptional activation of plant immunity by salicylic acid.
1. Nature - published September 1, 2026
2. Zhang S, Gish M, Li H, Hinds TR, Mao H, Cornell M, Silvetti M, Klucas S, Vorauer C, Mundorff CC, Yadav S, Guttman M, Zheng N
Longitudinal dynamics and lineage cross-reactivity of the human antibody response to West Nile virus.
1. mBio - published September 1, 2026
2. Leach AG, Xu L, Malakar S, Pacenti M, Vogiatzis S, Kumar S, Vander Velden J, Wang M, Kendzel MJ, Zarnitsyna VI, Hui S, Nguyen MN, Nelson CA, Ferrell T, Neufeldt CJ, Fremont DH, Menachery VD, Busch MP, Norris PJ, Lanteri M, Barzon L, Wrammert J, Suthar MS
Yersinopine is a primary zinc acquisition system for Yersinia pseudotuberculosis.
1. mBio - published September 1, 2026
2. Kadari M, Weber C, Kehl-Fie TE, Perry RD, Ortiz-Marquez JC, Tsodikov OV, Garneau-Tsodikova S, Lawrenz MB
Author Correction: Arf1 is involved in Neisseria meningitidis-induced cortical branched F-actin network reorganization.
1. EMBO Rep - published September 1, 2026
2. Sahnine M, Crochet M, Tachon S, Goussard S, Pénard E, Scandola C, Duchateau M, Giai Gianetto Q, Salles A, Moneron G, Swistak L, Charles-Orszag A, Mallet A, Matondo M, Tinevez JY, Bonazzi D, Sartori-Rupp A, Duménil G, Obino D
Thinking Outside the Binding Site: A Self-Encapsulating Kinase Inhibitor Remodels Its Pocket to Achieve Selectivity.
1. Angew Chem Int Ed Engl - published September 1, 2026
2. Seidler NJ, MacDonald MR, Moschopoulou AA, Cunningham S, Weber TM, Nasief NN, Mayer L, Hacker FW, Hermann E, Möllers MB, Skliarenko Y, Damghani T, Manzar AN, Lin KS, Rudalska R, Goettert MI, Zender L, Dauch D, Forster M, Laufer SA, Heppner DE
Tunneling nanotubes regulate mitochondrial homeostasis between glioblastoma and astrocytes, and between tumor cells in vivo.
1. Nat Commun - published September 1, 2026
2. Saenz-de-Santa-Maria I, Pepe A, Tinevez JY, Brou C, Vitrenko Y, Cokelaer T, Cohen-Jonathan Moyal E, Weigert R, Zurzolo C
De Novo Design in an M(1) Positive Allosteric Modulator Backup Program: The Discovery of VU6069863.
1. ACS Med Chem Lett - published September 1, 2026
2. Han C, Rathnayake U, Gregro AR, Engers JL, Presley CC, Schley ND, Thompson Gray AD, Bubser M, Cho HP, Rodriguez AL, Kramlinger VM, Boutaud O, Niswender CM, Jones CK, Engers DW, Lindsley CW
Trypanosome Tpt1 is a bifunctional enzyme composed of tandem DEDDh nuclease and RNA 2'-phosphotransferase domains.
1. RNA - published September 1, 2026
2. Sarkar A, Ghosh S, Schwer B, Shuman S
Adenosine 5'-Carboxamide-Based Inhibitors of METTL1.
1. ACS Med Chem Lett - published September 1, 2026
2. Bobileva O, Nai F, Niedrite S, Mayordomo Soler L, Leite I, Caflisch A
Prevalence of pharmacogenomically implicated prescriptions in multi-ethnic populations in Singapore.
1. Br J Clin Pharmacol - published September 1, 2026
2. Loo ZZX, Li Z, Lee SZX, Sin MT, Tai ES, Ngiam KY, Lo EAG, Yang JJ
SNOR: a path for ribosome recovery after hibernation.
1. Trends Biochem Sci - published September 1, 2026
2. Saladin BA, Brito Querido J
Nitrile-Based Inhibitors Targeting both SARS-CoV‑2 Main Protease and Human Cathepsin L.
1. ACS Med Chem Lett - published September 1, 2026
2. Barasa L, Chen Y, Shaqra AM, Adnan SFZ, Intravaia LE, Huchaiah S, Allabaji A, S KK, Vidadala SR, Patil SN, Hale J, Schiffer CA, Fitzgerald KA, Thompson PR
Effect of IL-4RαR576 polymorphism on response to dupilumab in asthma, a genotype-stratified, randomized, placebo- controlled trial (IDEA Trial): Design, Rationale, Methods, Strategies, and Lessons Learned.
1. J Asthma - published September 1, 2026
2. Phipatanakul W, Israel E, Mauger DT, Kunselman SJ, Becker PM, Gagalis L, Dabek RL, Greenwood J, Kim H, Zoratti E, Kaelber DC, Ayache M, Jariwala S, Banerjee A, Oppenheimer J, Gaffin JM, Lai PS, Banzon TM, Thorne PS, Oettgen HC, Lee P, Lam M, Chatila T
Mechanism of Kch activation by Zn(2).
1. PNAS Nexus - published September 1, 2026
2. Morote-Costas B, Pan Y, Wang L, Bai X, Lockless SW, Zhou M
Circulating cholesterol fuels SARS-CoV-2 replication via ORF3a.
1. EMBO Rep - published September 1, 2026
2. Hayashi JM, Taha TY, Chen IP, Suryawanshi RK, Swaney DL, McCavitt-Malvido M, Montano M, Syed AM, Khalid MM, Simoneau CR, Chen PY, Leon KE, Tsou CL, Stevenson E, Gordon M, Chaplin NR, Jorgens DM, Wang Z, Puschnik AS, Doudna JA, Krogan NJ, Ott M
Discovery of a 4'-Azido Fleximer Nucleoside Analog With Broad-Spectrum Antiviral Activity Against DENV, EBOV, and Other RNA Viruses.
1. ChemMedChem - published September 1, 2026
2. Davis KA, Slack RL, Foulkes TR, Frčková T, Tomková L, Smith JL, Amare M, Pipher GD, Halfmann P, Hirsch AJ, Eyer L, Sarafianos SG, Seley-Radtke KL
Quantifying Biomolecule Concentration of Phase-Separated Condensates in Optofluidic Chips.
1. ACS Sens - published September 1, 2026
2. Tang J, Chiara Kathe N, Lee SS, Novakovic M, Allain FH, Tao Y, Chen X, Kolf K, Qiu G, Wang J
Mapping structural constraints and adaptive potential in a capsule-degrading phage tailspike protein.
1. Sci Adv - published September 1, 2026
2. Evert S, Huss P, Kuppa Baskaran DK, Anantharaman K, Raman S
Inhibition of Fosfomycin Resistance Protein FosA from Pseudomonas aeruginosa.
1. ACS Infect Dis - published September 1, 2026
2. Wiltsie V, Smith T, Thamban Chandrika N, Gilbert NC, Garneau-Tsodikova S, Thompson MK
Structural basis of active state coupling of metabotropic glutamate receptor 8 to beta-arrestins.
1. Nat Commun - published September 1, 2026
2. Marx DC, Huynh K, Gonzalez-Hernandez AJ, Strauss A, Rico C, Gallo PN, Sharghi Moshtaghin S, Arefin A, Broichhagen J, Eliezer D, Khelashvili G, Levitz J
Configurational diversity of metabotropic glutamate receptor complexes with beta-arrestins.
1. Nat Commun - published September 1, 2026
2. Marx DC, Gonzalez-Hernandez AJ, Lee J, Siepe D, Weber WF, Huynh K, Gallo PN, Sharghi Moshtaghin S, Arefin A, Broichhagen J, Kalocsay M, Eliezer D, Levitz J
Development of GS-441524 derivatives as potent SARS-CoV-2 Mac1 inhibitors via a direct-to-biology approach.
1. Eur J Med Chem - published September 1, 2026
2. Peng K, Chakraborty S, Wallace SD, Noll JCG, Shang J, Lu X, Choi A, Whittaker G, Fromme JC, Lin H
Mechanism of membrane perforation in rotavirus cell entry.
1. Science - published September 1, 2026
2. de Sautu M, Leistner C, Kirchhausen T, Jenni S, Harrison SC
Conserved assembly architecture of the essential herpesvirus packaging accessory factor.
1. PLoS Pathog - published September 1, 2026
2. Bailey EJ, Devarkar SC, Szczepaniak R, Meißner LM, Chen X, Wu C, Weller SK, Xiong Y, Didychuk AL
A HUWE1 regulatory helix gates ASCL1 degradation through its C-terminal phospho-degron in small cell lung cancer.
1. Genes Dev - published September 1, 2026
2. Masuzawa K, Dong KD, XiaoYang Hu C, Peng T, Myung Y, Singh S, Li X, Wang T, Jin C, Paulo JA, Yang K, Schmid EW, Booker MA, Li Y, Hong D, Lazo S, Tolstorukov MY, Doench JG, Duplaquet L, Donovan KA, Iqbal S, Fischer ES, Liau BB, Gygi SP, Oser MG
Predicting Targeted and Immunotherapeutic Response Outcomes in Melanoma With Single-Cell Raman Spectroscopy and Artificial Intelligence.
1. JCO Precis Oncol - published September 1, 2026
2. Chang K, Serasanambati M, Ogunlade B, Hsu HJ, Agolia J, Stiber A, Gu J, Chadokiya J, Rodriguez GE, Singh P, Sharma S, Gonçalves A, Verma O, Safir F, Vu N, Garcia KC, Delitto D, Kirane A, Dionne JA
What Antibody Repertoires See: Structural and Immunogenetic Insights Into Influenza A Virus Hemagglutinin Recognition.
1. Immunol Rev - published September 1, 2026
2. Bonnettaz B, Bajic G
Structure of NO16, a marine non-tailed vibriophage with an unusual symmetry-mismatched vertex arrangement.
1. PLoS Pathog - published September 1, 2026
2. Otaegi-Ugartemendia S, Condezo GN, Martínez M, Kalatzis PG, Middelboe M, San Martín C
Machine learning approaches for cancer prognosis and diagnosis via non-coding RNA: a comprehensive review.
1. Brief Bioinform - published September 1, 2026
2. Hossain MS, Chen YP
Cryo-Electron Tomography Reveals Nanoscale Thick Filament Disorganization in MYH7 P710R Hypertrophic Cardiomyopathy Cardiomyocytes.
1. ACS Nano - published September 1, 2026
2. Zaoralová M, Yoniles J, Giri P, Held RG, Vander Roest A, Dahlberg PD, Bernstein D, Dunn AR, Engel L
Structural and biophysical characterization of Mycobacterium tuberculosis DciA reveals functional convergence in DnaB helicase recognition.
1. Protein Sci - published September 1, 2026
2. Mazzoletti D, Garavaglia A, Fisher H, Gao N, Morrone C, Olinares PDB, Chait BT, Jeruzalmi D, Miggiano R
Towards routine accurate electron-density studies of biological macromolecules.
1. Acta Crystallogr D Struct Biol - published September 1, 2026
2. Paknia E, Flensburg C, Chodkiewicz ML, Fogh RH, Keller P, Vonrhein C, Schulze-Briese C, Dominiak PM, Bourenkov G, Bricogne G, Chari A
Reexamining the activation mechanisms of adhesion G protein-coupled receptors.
1. Sci Signal - published September 1, 2026
2. Araç D, Kordon SP
Identification of a key water molecule involved in the macrophage migration inhibitory factor-catalyzed tautomerization of para-hydroxyphenylpyruvate using neutron crystallography.
1. Protein Sci - published September 1, 2026
2. Schröder GC, Crichlow GV, Jablonowski E, Pantouris G, Nix J, Chayen N, Meilleur F, Lolis EJ
Conformational asymmetry of human immunodeficiency virus-1 protease flaps increases along the darunavir drug resistance pathway.
1. Protein Sci - published September 1, 2026
2. Guerrero M, Zadorozhnyi R, Lin G, Quinn CM, Calero G, Kurt-Yilmaz N, Schiffer CA, Polenova T, Gronenborn AM, Ishima R
Structural insights into fosfomycin efflux by a streptococcal ABC transporter.
1. Proc Natl Acad Sci U S A - published September 1, 2026
2. Taguchi A, Fujita J, Tanabe M, Takaya D, Harada K, Moriya T, Fukuzawa K, Namba K, Nishino K
Engineering antigenic breadth against SARS-CoV-2 by pairing divergent RBDs within a single mRNA immunogen.
1. Proc Natl Acad Sci U S A - published September 1, 2026
2. Montgomerie I, McKenzie RE, Palmer OR, Mason NC, Kuang J, Pankhurst TE, Draper SL, von Daake S, Eccles DA, Bird TW, Martin AL, Green I, White L, Robinson Z, Marshall A, Minnell JJ, Small SJ, Hermans IF, Painter GF, Ussher JE, Quiñones-Mateu ME, Patrick WM, Comoletti D, Connor LM
Structural basis of GSDME pore formation and its regulation by S-palmitoylation.
1. Proc Natl Acad Sci U S A - published September 1, 2026
2. Du G, Ehrmann JF, Lieberman J, Wu H
Avoiding pitfalls when modelling ligands in macromolecular crystallography.
1. Acta Crystallogr D Struct Biol - published September 1, 2026
2. Smart OS, Sharff A, Flensburg C, Vonrhein C, Bricogne G
A novel corneal epithelial cell culture assay for assessing topical antivirals against herpes simplex virus keratitis.
1. Biochem Biophys Rep - published September 1, 2026
2. Kuniyoshi H, Numata Y, Sasano M, Hayashi H, Fuse N, Sarafianos SG, Kodama EN
Multiobjective learning and design of bacteriophage specificity.
1. Cell Syst - published September 1, 2026
2. Novy N, Huss P, Evert S, Romero PA, Raman S