This nanocourse has been organized in Boston, MA, and is offered for credit to Harvard graduate students and all SBGrid affiliates. In two workshops we will introduce the SBGrid environment, teach basic UNIX commands, and introduce the RCSB Protein Data Bank file formats. Subsequently, course participants will scrutinize the structure of clathrin coats, 7.7 MDa hexagonal barrel particles, visualize macromolecular properties including side-chain interactions, electrostatic potential, hydrophobicity and solvent accessible area, as well as perform secondary structure identification and structure quality verification. Participants will also learn how to transform coordinates, assemble biological units using symmetry operators, and animate structures. Software tools covered in this course will include ccp4mg, chimera, coot, whatif and procheck. Class will take place in the CMCD computer rooms. Space is limited; please contact Meg Bentley (meg_bentley@hms.harvard.edu) to enroll. September 18th and 25th, 1-4pm. Lecturers: Piotr Sliz, Stephen C. Harrison and James Chou.