The SBGrid Consortium and NSF RCN would like to invite you to a Centrifugation Workshop to be held at Harvard Medical School:
"Structure-function studies using analytical ultracentrifugation, and the UltraScan data analysis suite"
Dr. Borries Demeler, Associate Professor of Biochemistry The University of Texas Health Science Center at San Antonio
Friday, May 20, 2011 9:30am-5:00pm Countway Library, Room 403, Harvard Medical School 10 Shattuck St, Boston, MA 02115
Hosted by: Piotr Sliz
Registration is closed
Description:
In this workshop Dr. Demeler will provide an overview of the analytical ultracentrifugation technique. This workshop will be of interest to structural biologists, biochemists and biophysicists interested in solution characterization of macromolecules, their interactions and assemblies. During the workshop Dr. Demeler will review the background of sedimentation velocity experiments, discuss the observable parameters, the types of data collected, and the modelling approaches used for extracting molecular parameters from the data. Using tools in UltraScan, he will demonstrate the entire workflow from experimental design to data management, modelling and optimization, visualization and reporting. He will demonstrate the software using several representative examples, using both the UltraScan GUI application and the UltraScan LIMS system, a web-based MySQL database, and the TeraGrid Science Gateway portal for UltraScan. Dr. Demeler will then discuss the SoMo (Solution Modeler) rigid body bead modelling suite, its relevance to X-ray and NMR experiments, and conclude with perspectives of developments currently underway in our laboratory.
For questions regarding this workshop, please contact the SBGrid consortium at events@sbgrid.org.