Member Publications

Jump to specific year:

117 Member Publications for October 2026

Real-time exploration of the billion-scale human repertoire for precursor frequency analysis and rational antibody design.
1. Front Immunol - published October 31, 2026
2. Schlegel TU, von Blanckenburg de Riz J, Riccabona JR, Dietzmeyer F, Koehler Leman J, Meiler J, Schoeder CT, Schiffner T
A single anion exchange chromatography step enables scalable, high-yield purification of hepatitis B virus capsid virus-like particles.
1. Front Microbiol - published October 24, 2026
2. Seidler A, Ambike S, Peters C, Bester R, Sattler M, Geerlof A, Protzer U
RCSB PDB AI Help Desk: retrieval-augmented generation for protein structure deposition support.
1. Bioinform Adv - published October 10, 2026
2. Chithari VR, Young JY, Persikova I, Liang Y, Crichlow GV, Flatt JW, Ghosh S, Hudson BP, Peisach E, Sekharan M, Shao C, Burley SK
Unbiased, systematic surfaceome profiling of Acute Leukemia to identify novel immunotherapy targets.
1. bioRxiv - published October 9, 2026
2. George BM, Rodriguez-Pöhnlein A, DeCastro DJ, Porat J, Zhou B, Abeja DM, Lumpkin RJ, Metivier RJ, Schmoker A, Walter W, Haferlach T, Pikman Y, Donovan KA, Stegmaier K, Fischer ES, Wachter F, Flynn RA
The IKK complex and TBK1/IKKε are recruited to STING through distinct mechanisms to activate NF-κB signaling.
1. Sci Immunol - published October 9, 2026
2. Christensen AH, Jurkiewicz AJ, Jensen CS, Kjøge K, Luo W, He W, Chen Y, Liu J, Dalskov L, Bagger AB, Winther KG, Gulstad KG, Lorentzen A, Haas G, Kamper JM, Stafford C, Gyrd-Hansen M, Enghild JJ, Hornung V, Cai H, Imler JL, Gad HH, Hartmann R
Temporal transcriptomics identifies transregulation by multiple lncRNAs in human iPSCs.
1. Genome Res - published October 9, 2026
2. Liu M, Mamede I, Sofi S, Pereira I, Dostal V, Pashos ARS, McMahon C, Waikar A, Stephenson G, Cech TR, Rinn JL
Keratin filaments and soluble vimentin interact with isoform specificity to organize cell signaling.
1. Genes Dev - published October 9, 2026
2. Chouhan S, Boujemaa-Paterski R, Munawar S, Bhatt K, German Do Nascimiento L, Li A, Gałecki S, Rajendran D, Isogai T, Dean KM, Danuser G, Medalia O, Nanes BA
An integrated open-source acquisition and analysis ecosystem for high-throughput single-molecule imaging.
1. Nat Methods - published October 9, 2026
2. Terry DS, Kiselev R, Juette MF, Kilic Z, Brady RA, Sun Y, Blanchard SC
Transcription factor interactions promote binding to non-cognate DNA sites.
1. bioRxiv - published October 9, 2026
2. Du YJ, Yan Y, Halic M
Drug-specific resistance mechanisms to RET inhibitors in RET fusion-positive NSCLC.
1. Clin Cancer Res - published October 8, 2026
2. Liu X, Paula AG, Nilsson MB, Cai L, He J, Huo X, Kumar A, Wang K, Yekeen A, Westover KD, Araujo HA, Heymach JV, Kittler R
Validation and analysis of 12,000 AI-driven CAR-T designs in the Bits to Binders competition.
1. Mol Syst Biol - published October 8, 2026
2. Kosonocky CW, Abel AM, Feller AL, Cifuentes Rieffer AE, Woolley PR, Lála J, Barth DR, Gardner T, Bits to Binders Competitors, Ekker SC, Ellington AD, Wierson WA, Marcotte EM
Scope and Differences between ACS Medicinal Chemistry Letters and Journal of Medicinal Chemistry.
1. ACS Med Chem Lett - published October 8, 2026
2. Chibale K, Lindsley CW
Programming N-linked glycan composition through de novo protein design.
1. bioRxiv - published October 8, 2026
2. Lunn-Halbert MC, Allen JD, Krishna R, Manchenko A, Li X, Lopatto E, Pinkner J, Moller C, Ahern W, Mendoza J, Kang A, Nguyen H, Joyce E, Bera A, Hultgren SJ, Sokurenko E, Crispin M, Baker D, King NP
Mechanism of spliceosome termination.
1. Nature - published October 7, 2026
2. Boreikaite V, Faraway R, Vorländer MK, Phillips AW, Opitz L, Wanke M, Yakoub G, Raffl G, Fin L, González-Prieto R, Luijsterburg MS, Ameres SL, Plaschka C
Structural basis for regulating lipopolysaccharide transmembrane transport.
1. Nature - published October 7, 2026
2. Taylor RJ, Pahil KS, Caruso A, Plaman B, Early SA, Rowe SJ, Baidin V, Wilson A, Ruiz N, Walsh RM Jr, Harrison SC, Kahne D
Human lung organoid modelling of tissue-resident antiviral T cell responses.
1. Nature - published October 7, 2026
2. Rathkey JK, Choi SS, van Unen V, Zhang H, Liu M, Ding J, Alwahabi SA, Santos AJM, Mallajosyula V, Chan JE, Mohsin A, Elsheikh MM, Rustagi A, Lam B, Chirieleison SM, Wallen B, Solis D, Mah J, Horn HT, Röltgen K, Nair R, Trope W, Guh-Siesel A, Lin Z, Powell HS, Salehi A, Beck A, Edwards C, Martin BA, Dunn JCY, Shrager J, Baric RS, Pinsky B, Boyd SD, Blish CA, Sette A, Grifoni A, Davis MM, Kuo CJ
SNX17 facilitates entry and infection of Rift Valley fever virus and related bunyaviruses.
1. Cell Rep - published October 7, 2026
2. Ganaie SS, Fatma F, Hu Z, Grodzki M, Rush RE, Clees J, Brown G, Barreca O, Cui X, Cho BK, Goo YA, Hartman AL, Leung DW, Amarasinghe GK
HelD is a global transcription factor enhancing gene expression in rapidly growing mycobacteria.
1. Microbiol Res - published October 7, 2026
2. Vaňková Hausnerová V, Kumar D, Neva S, Shoman M, Schwarz M, Modrák M, Jirát Matějčková J, Brázda P, Havelková J, Capdevila AC, Šiková M, Pospíšilová D, Halada P, Šanderová H, Holubová J, Dohál M, Převorovský M, Staněk O, Knejzlík Z, Kouba T, Dvořáková V, Hnilicová J
Catalysis tuned for metabolic sensing: dynamics and mechanism of the RNA methyltransferase METTL16.
1. RSC Chem Biol - published October 7, 2026
2. Stamm F, Wan Z, Vargas-Rosales PA, Corbeski I, Braud E, Iannazzo L, Cui Q, Caflisch A
A bacterial endosymbiont with a highly reduced genome forms extensive membrane contact sites with host organelles.
1. bioRxiv - published October 7, 2026
2. Leprich DJ, Aaron J, Hughes E, Ladinsky MS, Bjorkman PJ, McCutcheon JP
Cnidarian mechanosensory cells as ancestors of vertebrate hair cells: Molecular targeting of an ancient mechanotransduction complex.
1. Proc Natl Acad Sci U S A - published October 6, 2026
2. Banday ZZ, Randich AM, Hulse RE, Tong Z, Havrilak JA, Osorno-Ferro T, Watto E, Demchenko EA, Fournier Z, Grillet N, Sotomayor M, Layden MJ, Malamy J, Perozo E
PKD2-like proteins target Chlamydomonas PKD2 to distinct subciliary regions.
1. Proc Natl Acad Sci U S A - published October 6, 2026
2. Das P, Zhou H, Sureshkumar S, Chasen N, Dai J, Brown A, Lechtreck K
Mechanisms of substrate recognition and catalysis in a mammalian phosphatidylserine synthase 2.
1. Proc Natl Acad Sci U S A - published October 6, 2026
2. Wang L, Zhang Z, Yang H, Laganowsky A, Zhou M
LAT condensation gates PLCγ1 activation via bimodal LAT phosphorylation.
1. Proc Natl Acad Sci U S A - published October 6, 2026
2. Ren H, Lee HR, Omar YAD, DeGrandchamp JB, Hung CL, Eisen TJ, Stamou D, Kuriyan J, Chakraborty AK, Groves JT
The mycomembrane proteins PorH and ProtX are inserted at polar growth zones and linked to the cell wall.
1. Proc Natl Acad Sci U S A - published October 6, 2026
2. Hart EM, de Bruin DA, Marando VM, Arnau Alemany M, Snow ED, Schultz BJ, Kuru E, Walker S, Vettiger A, Bernhardt TG
Nuclear prohibitin 1 depletion drives alcohol-associated liver injury and sensitization to colon cancer liver metastasis.
1. J Clin Invest - published October 6, 2026
2. Chhimwal J, Sinha S, Kim J, Alba M, Barbier-Torres L, Wang J, Yang H, Lim Y, Murali R, Tomasi ML, You S, Mato JM, Lu SC
Late effects after novel therapies for childhood cancer: Anticipating the future landscape of health outcomes for survivors.
1. J Natl Cancer Inst - published October 6, 2026
2. Berkman AM, Teachey DT, Ehrhardt MJ, Pui CH, Inaba H, Karol SE, Castellino SM, Dixon SB, Yang JJ, Gross TG, Federico SM, Packer RJ, Pappo AS, Qaddoumi I, Salloum R, Smith SM, Cooper T, Henderson TO, Hawkins DS, Nathan PC, Chow EJ, Fox E, Armstrong GT
SPARCS enables scalable recovery of complex image-based phenotypes for genetic screening.
1. Cell - published October 6, 2026
2. Schmacke NA, Mädler SC, Wallmann G, Metousis A, Varlamova V, Steigerwald S, Christ SB, Bérouti M, Harz H, Leonhardt H, Theis FJ, Mann M, Hornung V
Characterization of Regioisomeric Conjugates Arising from Pixantrone at AP Sites in DNA.
1. Biochemistry - published October 6, 2026
2. Fu Y, Terrell JT, Kellum A, Pallan PS, Galindo-Murillo R, Rizzo CJ, Egli M, Stone MP
Genomic drivers of leukemia and blinatumomab response in adult acute lymphoblastic leukemia - the ECOG-ACRIN E1910 study.
1. Blood - published October 5, 2026
2. Zhong X, Roberts KG, Wei H, Sun Z, Montefiori LE, Kumar A, Iacobucci I, Baviskar P, Gao Q, Pölönen P, Pruett-Miller SM, Schreiber RM, Chang TC, Zhang W, Lei S, Rampersaud E, Fan Y, Wu G, Mattison RJ, Zhang Y, Racevskis J, Lazarus HM, Rowe JM, Arber DA, Wieduwilt MJ, Abou Mourad Y, Shami PJ, Baer MR, Asch AS, O'Dwyer KM, Hall A, Liedtke M, Bergeron J, Wood BL, Pratz KW, Dinner SN, Frey NV, Gore SD, Bhatnagar B, Atallah EL, Uy GL, Jeyakumar D, Lin TL, Willman CL, Podoltsev NA, DeAngelo DJ, Patel S, Elliott MA, Advani AS, Tzachanis D, Vachhani P, Bhave RR, Sharon E, Little RF, Erba HP, Stone RM, Tallman MS, Yang JJ, Luger SM, Paietta E, Litzow MR, Mullighan CG
Differential formation of nitrate-responsive mycobacterial intracytoplasmic membranes during Mycobacterium tuberculosis infection.
1. Cell Rep - published October 5, 2026
2. Keck C, Tachon S, Sayes F, Musiani D, Gianetto QG, Matondo M, Vos M, Brosch R, Enninga J
The RNA helicase KREH2 directly binds the RESC1-RESC2 complex in trypanosomatid mitochondrial RNA editing.
1. bioRxiv - published October 5, 2026
2. Yelmar R, Dolce LG, Tengo L, Gabiatti BP, Corwin J, O'Hara L, Goode C, Sharma SK, Rodshagen T, Goodall Z, Cruz-Reyes J, McDermott SM, Kowalinski E
Near-atomistic simulations reveal the molecular principles that control chromatin structure and phase separation.
1. Nat Commun - published October 3, 2026
2. Russell K, Chen Y, Espinosa JR, Farré-Gil D, Zhou H, Maristany MJ, Perez-Lopez JI, Huertas J, Orozco M, Rosen MK, Collepardo-Guevara R
Structure of vesicular stomatitis virus L-P-N(0) complex by cyro-electron microscopy.
1. Sci Adv - published October 3, 2026
2. Bloyet LM, Whelan SPJ
Distinct allosteric remodeling of HIV-1 Env dynamics on virions by gp41-directed antibodies reveals two modes of neutralization.
1. Elife - published October 2, 2026
2. Xu W, Gonepudi NK, Liu J, He Y, Katte R, Wang R, Awuah HB, Han Y, Zhang B, Yu J, Hu B, Ho DD, Acharya P, Kwong PD, Lu M
Transposon end recognition and pairing by I-F3 CRISPR-associated transposase.
1. Sci Adv - published October 2, 2026
2. Truong VH, Miller DJ, Fatma S, Sheng Y, Pindi C, Ahsan M, Palermo G, Kellogg EH
A muscle-enriched mitochondrial protein regulates postnatal heart growth through mitonuclear ubiquinone-PPAR signaling.
1. Proc Natl Acad Sci U S A - published October 2, 2026
2. Hirose K, Chen X, Kalyanaraman C, Waddingham MT, Nakamura M, Zhang F, Chen C, Yao S, Chang S, Yu H, Wang J, Barca E, Nakano H, Hsu A, Khyeam S, Gonzalez Ortega S, Tajima K, Yoneshiro T, Zhang H, Padmanabhan A, Kajimura S, Haldar S, Nakano A, Murai M, Fujihara Y, Otsu K, Quinzii CM, Jacobson MP, Hu G, Pearson JT, Huang GN
Matrix metalloproteinase-guided targeting of vesicular stomatitis virus to tumors following systemic administration.
1. Signal Transduct Target Ther - published October 2, 2026
2. Theune EV, Theune WC, Ahmadi E, Chiari CC, Singh N, Geyer R, Tonne J, Metko M, Olaoba OT, Wang IC, Dai D, Ruan J, Clark R, Li G, Wang P, Jellison ER, Vella AT, Vile R, Wang K
Modulating Radical Propagation in Proteins by Proton-Coupled Electron Transfer and Hydrogen Bonding.
1. Biochemistry - published October 2, 2026
2. Zawistowski RK, Chauviré T, Manna S, Ananth N, Crane BR
In Pursuit of Enduring Inactivation: A Perspective on the Development and Study of Irreversible-Covalent Inhibitors.
1. Biochemistry - published October 2, 2026
2. Gehringer M, Heppner DE
Interplay between Thermal Denaturation and Dynamic Covalent Chemistry Generates High-Performance Recyclable Protein Plastics.
1. ACS Macro Lett - published October 2, 2026
2. Ma Y, Stellacci F
Molecular basis for discrimination of cGAMP linkage isomers by a c-di-GMP-II riboswitch variant.
1. Proc Natl Acad Sci U S A - published October 2, 2026
2. Xu X, Cheng W, You H, Hu Z, Bao X, Li H, Zhang J, Patel DJ, Ren A
Correction to "Discovery of VU6077564: A Selective M1 Antagonist that Promotes Neurite Outgrowth in Adult Sensory Neurons".
1. ACS Chem Neurosci - published October 2, 2026
2. Berida TI, Dodd CJ, Wilkinson JC, Smith DR, Chang S, Presley CC, Peng L, Sant S, Krishnan S, Zagol-Ikapitte I, Watson KJ, Thompson Gray A, Rodriguez AL, Cho HP, Jones CK, Boutaud O, Niswender CM, Engers DW, Fernyhough P, Lindsley CW, Childress ES
Structural basis for protocadherin-1 recognition by New World hantaviruses.
1. Nature - published October 2, 2026
2. Battini L, Slough MM, Kaur R, Guo L, Florez C, Serris A, Meola A, Lasso G, Tischler ND, Alvarez R, Lambe UP, Khera L, Wang J, Scott RS, Garrido JL, Barria MI, Josleyn NM, Rey FA, Herbert AS, McLellan JS, Jangra RK, Chandran K, Guardado-Calvo P
Mitochondrial dysfunction in Down syndrome B-cell acute lymphoblastic leukemia can be targeted using venetoclax.
1. Haematologica - published October 2, 2026
2. Jones D, Woods E, Li Z, Schaller KL, Hoffmeyer E, Kooiman B, Fernandez J, Wharton T, Tufa D, Hall SC, Trahan G, Maloney KW, Pacenta H, Sullivan K, Espinosa J, Roede JR, Marentette J, Stevens B, Inguva A, Stephenson D, Reisz JA, D'Alessandro A, Jordan CT, Yang JJ, Verneris MR
PARP1 directly disassembles nucleosomes to regulate DNA repair.
1. Mol Cell - published October 2, 2026
2. Verma A, Zhu C, Truong B, Bilokapic S, DeVries R, Pitre A, Bhat YA, Shelat AA, Halic M, Dao HT
Structural analyses of a heterodimeric SusCD complex captures intermediate states of maltooligosaccharide transport.
1. J Biol Chem - published October 2, 2026
2. Cadigan MC, Fuentes NR, Salmen W, Roberts JR, Ruotolo B, Ohi MD, Koropatkin NM
Predicted structure of the complete CPLANE complex reveals novel interactors and mechanisms of Jbts17 during ciliogenesis.
1. Mol Biol Cell - published October 2, 2026
2. Gardner T, Prolomova A, Lee C, Marcotte EM, Wallingford JB
Discussions with the gene editor.
1. Nat Rev Chem - published October 2, 2026
2. Zhang F, Greed S
RAF isoform selectivity of MEK inhibitors and rational design of a covalent ARAF-MEK inhibitor.
1. Sci Adv - published October 2, 2026
2. Chakraborty S, Jiang J, Camallonga JV, Gazgalis D, Gero TW, Tavares MT, Dittemore G, Tkacik E, Beyett TS, Jang DM, Ha BH, Gottlieb FH, Levitz T, Metivier RJ, Schmoker AM, Scott DA, Jeon H, Jänne PA, Eck MJ
Opposing cell-type preferences for binding and replication shape influenza A virus infection in human airways.
1. Sci Adv - published October 2, 2026
2. von Kempis J, Pohl MO, Gaggioli E, Niklaus C, Trkola A, Boons GJ, de Vries RP, Stertz S
Deciphering the Structure-Activity Relationships Underpinning the Linkerology of Bivalent EGFR Inhibitors.
1. J Med Chem - published October 2, 2026
2. Patel KB, Akinwumi IA, Weber TM, MacDonald MR, Collins SJ, Chitnis SP, Zack CL, Ogboo BC, Nasief NN, Ouellette EA, Abidakun OA, Eck MJ, Brandt AL, Wittlinger F, Laufer SA, Nguyen HT, Heppner DE
Structural basis for start codon selection by eIF5-mimic proteins.
1. Sci Adv - published October 2, 2026
2. Zottig X, Huang CY, Seraj Z, Grigorieff N, Korostelev AA
Human astroviruses: molecular virology.
1. Microbiol Mol Biol Rev - published October 2, 2026
2. Lentz A, López T, Ykema M, Tao YJ, DuBois RM, Arias CF
Combined muscarinic receptor M(1) and M(4) stimulation reverses cocaine-induced attention deficits in male mice.
1. J Psychopharmacol - published October 2, 2026
2. Bornø L, Forsbøl MS, Yüksel O, Bonnevie V, Balakrishnan AS, Andreasen JT, Lindsley CW, Thomsen M
Cryo-EM and biochemical characterization of a BRAF/CRAF heterodimer shows that the NtA motif negative charge is dispensable for RAF activation.
1. Cell Rep - published October 2, 2026
2. Ha BH, Tkacik E, Gazgalis D, Kang H, Jang DM, Chakraborty S, Jeon H, Eck MJ
Potent Antivirals for Respiratory Syncytial Virus Detected via Peptide-Based Fusion Inhibitor Screening.
1. ACS Omega - published October 2, 2026
2. Suzuki S, Usui Y, Aoki K, Amano H, Hiramatsu Y, Nishiyama A, Hashimoto K, Murayama K, Hayashi H, Sarafianos SG, Oishi S, Kodama EN
E. coli RsmF activity depends on prior modification of 16S rRNA helix 44.
1. Nucleic Acids Res - published October 2, 2026
2. Barmada MI, Hanna A, Bair CR, McGinity EN, Zelinskaya N, Dey D, Conn GL
Comparative analysis of KMT2A fusions in human models of acute myeloid leukemia.
1. Exp Hematol - published October 2, 2026
2. Safa-Tahar-Henni S, Milan T, DesCôteaux T, Roques É, Bonnet-Magnaval F, Osborne MJ, Bresson E, Mathien S, Chazin WJ, Hébert J, Borden KLB, Najmanovich R, Cellot S, Barabé F, Wilhelm BT
Structural basis for coupled DNA replication and uracil repair by a family of DNA polymerases from phages with T-modified genomes.
1. Nucleic Acids Res - published October 2, 2026
2. Missoury S, Lucas-Staat S, Sieskind R, Delarue M
Modular synthesis of daptomycin analogues.
1. Org Biomol Chem - published October 2, 2026
2. Burchill L, Zhang T, Li W, Karas JA
Structural and kinetic basis of serine mono-ADP-ribosylation reversal by human ADP-ribosyl-acceptor hydrolase 3.
1. J Biol Chem - published October 2, 2026
2. Shrestha P, Lin S, Lederer A, Dharmapriya N, Pourfarjam Y, Medearis M, Heintel A, Tainer JA, Moss J, Kim IK
A scaffold for success: The many phases of herpesvirus capsid assembly.
1. Biochim Biophys Acta Mol Basis Dis - published October 2, 2026
2. Gordon SA, Latifi T, Pan XA, Draganova EB
SIR2-mediated filament assembly activates the NLR-like protein Avs5 for bacterial antiviral defense.
1. Cell Rep - published October 2, 2026
2. Wang C, Xie J, Shen Z, Ehrmann JF, Yu C, Fang MX, Wu H, Fu TM
Improved cryo-EM reconstruction of sub-50 kDa complexes using 2D template matching.
1. Elife - published October 2, 2026
2. Zhang K, Grant T, Grigorieff N
Amyloid-mediated RNA uptake by sperm for embryonic delivery.
1. Mol Cell - published October 2, 2026
2. Mallen WS, Zabello N, Brenner-Morton S, Sidoli S, Liang FX, Sall J, Yin J, Mathews P, Zhu M, Zhang G, Lee CL, Liao YC, Fitzpatrick AWP
Small genomes, big lessons: What viruses teach us about structure-based riboregulation.
1. Mol Cell - published October 2, 2026
2. Hann T, Jang H, Sung YC, Guh CL, Hiers NM, Tsao LH, Luo M, Pyle AM
PBPK Modeling Investigation of IVIVE-Observed Pharmacokinetic Divergence for VU0467319: A Mechanistic Refinement Workflow for Low-Solubility Compounds.
1. Pharmaceutics - published October 2, 2026
2. Abisogun AA, Krishnan S, Lindsley CW, Boutaud O
Recognition Loop Dynamics Differentiates m6A-mRNA Reader Domains of YTHDF Proteins.
1. J Chem Theory Comput - published October 2, 2026
2. Li Y, Bedi RK, Ojeda-May P, Caflisch A
Innate sensor responses set a supra-unitary threshold for viral replication.
1. Cell - published October 2, 2026
2. Mukai K, Jia D, Panigrahi M, Tayman T, Brogden G, Chen YH, Haque N, Arora G, Mutterperl JE, Poe I, Zhang C, Islam Z, Holewinski R, Andresson T, Wu D, Piszczek G, Marcotrigiano J, Hogg JR, De Ravin SS, Malik NS, Nath A, Viktorova E, Zimina A, Belov GA, Bayyurt-Kocabaş B, Altan-Bonnet G, Altan-Bonnet N
Lysinoalanine crosslinking in the extracellular flagellar hook of Synergistota.
1. J Bacteriol - published October 2, 2026
2. Lynch MJ, Charon NW, Crane BR
Preserving information and integrity in Cryo-EM: Toward a Fourier-space deposition approach.
1. J Struct Biol - published October 2, 2026
2. Otwinowski Z, Guo Y, Bromberg R, Borek D
Finding the Goldilocks zone: modulating glycoprotein cleavage and fusogenicity optimizes the efficacy of a candidate Crimean-Congo hemorrhagic fever virus vaccine.
1. mBio - published October 2, 2026
2. Berrigan J, Monticelli SR, Spealman P, Cohen CA, Batchelor TG, Wang A, McFadden E, Bakken RR, Slough MM, Wirchnianski AS, Mittler E, Cross RW, Geisbert TW, Erasmus JH, Hawman DW, McLellan JS, Herbert AS, Chandran K
Multiplexed Fc array assays reveal the influence of TLR3 on the Th1-biased humoral response induced in mice following live-attenuated RVFV vaccination.
1. J Virol - published October 2, 2026
2. Divens AM, Mueller Brown K, Barbeau DJ, Fatma F, Allen C, Price DA, Leung DW, Amarasinghe GK, McElroy AK
Methylated eEF1A selectively decodes mRNA to shape cancer proteomes.
1. Nat Cell Biol - published October 2, 2026
2. Liu S, Cruz-Navarrete FA, Hausmann S, Szkop KJ, Ikram S, Brady RA, Lu X, Dong R, Vu J, Flores NM, Zahn E, Thompson J, Garcia BA, Larsson O, Topisirovic I, Blanchard SC, Gozani O, Mazur PK
Overcoming EGFR Resistance by Monovalent and Bident Inhibitors Targeting Cys775.
1. ACS Cent Sci - published October 2, 2026
2. Li Z, Jiang J, Wang Y, Ficarro SB, Collins SJ, Beyett TS, Schaeffner IK, Tavares I, Gottlieb FH, Suda D, Gokhale PC, Black-Holmes LM, Gazgalis D, Eck MJ, Jänne PA, Marto JA, Che J, Gray NS, Zhang T
1,3-Dioxolane derived nucleos(t)ides: synthetic strategies, current position, and future promise in antiviral and anticancer drug discovery.
1. Med Chem Res - published October 1, 2026
2. Gudi M, Estes J, Kothapalli Y, Sarafianos SG, Singh US
Deacetylation degree modulates interfacial interactions and delivery performance of konjac glucomannan-soy protein microcapsules for encapsulating Zanthoxylum bungeanum essential oil.
1. Food Res Int - published October 1, 2026
2. Pan Y, Zeng Z, Fan J, Zhou M, Lu M, Chen Z, Rao C, Liu X
Separating the effects of temperature and absorbed X-ray dose on unit-cell volume.
1. Acta Crystallogr D Struct Biol - published October 1, 2026
2. Southworth-Davies RJ, Murray JW, Carmichael I, Rudiño-Piñera E, Weik M, Garman EF
Mitochondrial proteome of Acanthamoeba delineates aerobic and anaerobic pathways dynamically regulated by oxygen.
1. Cell - published October 1, 2026
2. Stefely JA, Deng FG, Chen MZ, Nguyen K, Luce BE, Fry MY, Guo XA, Maliaris K, Rivera KD, Papanastasiou M, Issa TM, Kanakapura Sundararaj B, Root SLY, Mani DR, MitoCarta Tree of Life Consortium, Chao LH, Calvo SE, Udeshi ND, Samuelson J, Mootha VK
A high-confidence inventory of the proteins in the mitochondrion-related organelle of Giardia.
1. Curr Biol - published October 1, 2026
2. Goyal M, Issa TM, Stefely JA, Venkatraman K, McCoy JG, Lam SS, Chen MZ, Nguyen K, Lian CG, Jean-Beltran PM, Fry MY, Luce BE, MitoCarta Tree of Life Consortium, Chao LH, Carr SA, Udeshi ND, Calvo SE, Mootha VK, Samuelson J
Mitochondrial proteome of the apicomplexan Babesia divergens.
1. Curr Biol - published October 1, 2026
2. Betsinger CN, Calvo SE, Mian SY, Bauer NC, Paul AS, Batzli DL, Lian CG, Boyle BW, Rivera KD, Sreenivasamurthy SK, McCoy JG, Chen MZ, Issa TM, Stefely JA, MitoCarta Tree of Life Consortium, Dvorin JD, Udeshi ND, Duraisingh MT, Mootha VK
Acanthamoeba ATP synthase structure reveals the TCA cycle is tethered to OXPHOS.
1. Cell - published October 1, 2026
2. Fry MY, Luce BE, Stefely JA, Chen MZ, Deng FG, Issa TM, MitoCarta Tree of Life Consortium, Calvo SE, Samuelson J, Mootha VK, Chao LH
Phage proteases activate CBASS antiphage immunity.
1. Science - published October 1, 2026
2. Hobbs SJ, Kranzusch PJ
Molecular glue everywhere: Metabolites join the party.
1. Mol Cell - published October 1, 2026
2. Wang B, Zheng N
Conserved and divergent mitochondrial assemblies in kinetoplastid parasites.
1. Mol Cell - published October 1, 2026
2. Solayman M, Liao YT, Calvo SE, Vacas AF, Papanastasiou M, Rivera KD, Mani DR, Boyle BW, Deng FG, MitoCarta Tree of Life Consortium, Udeshi ND, Mootha VK, Aphasizheva I, Chao LH, Aphasizhev R
The CUP pilus SMF-1 utilizes a specific antiparallel bundling mechanism to initiate biofilm formation.
1. Cell Rep - published October 1, 2026
2. Fields JL, Sebastian CC, Zhang H, Bhaumik R, Zia A, Robertson AN, Anderson GG, Mattoo S, Wu H, Kiedrowski MR, Wang F
Protocol for brain and ventricle volume comparison after clearing and light-sheet microscopy in mice.
1. STAR Protoc - published October 1, 2026
2. Blas-Medina A, Phan MS, Ali-Moussa S, Spassky N, Fernandes J, Tinevez JY, Deczkowska A, Travier L
QuickProcess2: an integrated package for crystallography data visualization, processing and management at the GM/CA Structural Biology Facility.
1. J Appl Crystallogr - published October 1, 2026
2. Xu Q, Hilgart MC, Venugopalan N, Kissick D, Becker M, Xu S, Makarov O, Stepanov S, Smith JL, Fischetti RF
Inducible dCas12a system expands CRISPRi/a capabilities for functional genomics in malaria parasite Plasmodium falciparum.
1. iScience - published October 1, 2026
2. Lucky AB, Li X, Kobakhidze G, Gonzales JL, Wang C, Cui L, Dong G, Miao J
Serum IgM crosslinks hepatitis B subviral particles into supramolecular immune complexes.
1. bioRxiv - published October 1, 2026
2. Liu C, Dhawan A, Yao X, Park J, Penna G, Mulligan S, Beaver A, Chen H, Donati F, Urban S, Bartenschlager R, Georgiou G, Nkongolo S, Seitz S, Ke Z
Taccalonolide AJ uncouples tubulin GTP hydrolysis from microtubule depolymerization.
1. bioRxiv - published October 1, 2026
2. Thomas EC, Vangos N, McCormick LA, Blasius L, Verhey KJ, Risinger AL, Cianfrocco MA
Molecular mechanism of KRAS binding to BRAF and its regulation by the BRAF-specific region.
1. Structure - published October 1, 2026
2. Bonsor DA, Sandin Lawrence SI, Tran TH, Swain M, Dharmaiah S, Mehalko J, Messing SA, Nissley DV, McCormick F, Stephen AG, Simanshu DK
Product-stabilized filamentation by human glutamine synthetase allosterically tunes metabolic activity.
1. Elife - published October 1, 2026
2. Greene E, Muniz R, Yamamura H, Hoff SE, Bajaj P, Tecson MCB, Geluz C, Lee DJ, Thompson EM, Arada A, Lee GM, Bonomi M, Kollman JM, Fraser JS
Extended local deuteration of leucine enhances methyl NMR of large proteins expressed in eukaryotic cells.
1. Chem Commun (Camb) - published October 1, 2026
2. Schindler S, Dubey A, Mallis RJ, Radeva DL, Georgieva NG, Burdzhiev NT, Knödlstorfer S, Reinherz EL, Gelev VM, Arthanari H
Structural basis of directionality control in large serine integrases.
1. Mol Cell - published October 1, 2026
2. Shin H, Pigli Y, Peña Reyes T, Bello AJ, Taiwo-Aiyerin OT, Fuller JR, Olorunniji FJ, Rice PA
Structural basis and rational engineering of a thermophilic Cas13a for robust RNA detection.
1. Cell Chem Biol - published October 1, 2026
2. Oladeji SJ, Gonzalez DH, Deng X, You Z, Zhang Y, Golla DA, Smith J, Zhang Y, Gao X, Lillehoj PB, Gao Y
Noncoding RNAs in Cancer: Functions, Mechanisms, and Targeting Approaches.
1. Annu Rev Pathol - published October 1, 2026
2. Montero JJ, Braun CJ, Sattler M, Rad R
In vivo engineering of CAR natural killer cells for immunotherapy using ligand-directed lipid nanoparticles.
1. Nat Biotechnol - published October 1, 2026
2. Chen Y, Monkovic J, Mughal H, Chen B, Thadhani E, McMullen P, Self A, Chen Y, Hu Y, Detmer S, Chen M, Lapteva A, Kamat R, Vernon A, Langer R, Anderson DG
Atomic, structural and molecular insights into GPCR ligand binding and signalling.
1. Nat Rev Mol Cell Biol - published October 1, 2026
2. Nemec K, Mészáros B, Skiniotis G, Blanchard SC, Babu MM
SPRIZ (CCDC127) protein conserved in deuterostome animals is a rigid OMM-IMM tether that locally sets mitochondrial IMS volume.
1. Sci Adv - published October 1, 2026
2. Shulinski R, Loban R, Farhat D, Cartes-Saavedra B, Magda MJ, Kotchetkov P, Caminiti V, David L, Wolf YI, O'Dwyer C, Fullerton M, Burelle Y, Lee JE, Raimondi A, Koonin EV, Hajnóczky G, Harper ME, Pellegrini L
Mitochondrial stress induces transcription of cytosolic and mitochondrial protein synthesis components via NHR-180.
1. Cell Rep - published October 1, 2026
2. Mallick A, Ramalho T, Ali L, Du Y, Hoang D, Li R, Rai P, Kim S, Ahsan R, Shaqra AM, Bergmann A, Schiffer CA, Zhu LJ, Kelch B, Shen K, Haynes CM
NCCN Guidelines® Insights: Hepatocellular Carcinoma, Version 2.2026.
1. J Natl Compr Canc Netw - published October 1, 2026
2. Benson AB 3rd, D'Angelica MI, Ahmed A, Akce M, Anaya DA, Anders R, Are C, Aye L, Bachini M, Baker M, Binder D, Burgoyne A, Castellanos J, Chokshi S, Cleary J, Cloyd J, Cullinan D, Dendy Case M, Franses J, Goyal L, Harris W, Jennings L, Kelley RK, Khan S, Krishnan M, Levine M, Melstrom L, Palta M, Raman S, Ronnekleiv-Kelly S, Sahai V, Stephans K, Thanikachalam K, Turk A, Vauthey JN, Venook AP, Wo J, Yano M, Yopp A, Zhao K, Hochstetler C, Schonfeld R, Stein M
A structurally defined nucleoplasmic-facing surface of Nup170 controls subtelomeric gene silencing.
1. Mol Biol Cell - published October 1, 2026
2. Choudhry SK, Neal ML, Saik NO, van Eeuwen T, Sariki SK, Li S, Mast FD, Wozniak RW, Rout MP, Aitchison JD
Variant escape site mapping and characterization of SARS-CoV-2 nucleocapsid rapid antigen test antibodies.
1. J Virol - published October 1, 2026
2. Keith AD, Keen MM, Frank F, Lam WA, Greenleaf M, Ortlund EA
A B1 SINE element within the mouse Malat1 long noncoding RNA acts as an internal ribosome entry site mediating micropeptide translation.
1. Sci Adv - published October 1, 2026
2. Xiao W, Hann T, Perry Z, Pandey V, Cheng J, Wohlschlegel J, Pyle AM, Black DL
Author Correction: Histone H3 proline 16 hydroxylation regulates mammalian gene expression.
1. Nat Genet - published October 1, 2026
2. Liu X, Wang J, Boyer JA, Gong W, Zhao S, Xie L, Wu Q, Zhang C, Jain K, Guo Y, Rodriguez J, Li M, Uryu H, Liao C, Hu L, Zhou J, Shi X, Tsai YH, Yan Q, Luo W, Chen X, Strahl BD, von Kriegsheim A, Zhang Q, Wang GG, Baldwin AS, Zhang Q
Advancing Pregnancy and Pediatric Science through the NIH Transporter Elucidation Network.
1. Clin Pharmacol Ther - published October 1, 2026
2. Wang J, Unadkat JD, Arnold SL, Fallon JK, Fattahi P, Huh DD, Ieronimakis N, Kelly EJ, Lutsenko S, Stroud RM, Tiley JB, Yang J, Zhou X, Zhu H, Rao R, Giacomini KM, Aleksunes LM
An opioid efficacy switch for reversible optical control of analgesia.
1. Cell - published October 1, 2026
2. Posa L, Romano GR, Ji X, Khan S, Nazarova AL, Sharghi Moshtaghin S, Paz B, Han GW, Arefin A, Gonzalez-Hernandez AJ, Srivastava I, Zaidi SA, Calderon-Godinez K, Zhang Z, Tyson AS, Ranjbar M, Pleil KE, Pande K, Katritch V, Gati C, Trauner D, Levitz J
Structural basis for cross-alphaherpesvirus neutralization by an antibody targeting a conserved hotspot on glycoprotein B.
1. Cell Rep - published October 1, 2026
2. Li Y, Yang C, Wang G, Zeng Y, Chen K, Jiang Y, Kang M, Chen T, Gui M, Bostina M, Li S, Xia N, Chen Y, Zheng Q
Substrate-bound structures of yeast ALA synthase reveal protein dynamics initiating heme biosynthesis.
1. Sci Adv - published October 1, 2026
2. Tran JU, Martinez TA, Jurich C, Josling MR, Zhang JM, Ayres-Galhardo PH, Meiler J, Yang ZJ, MacGurn JA, Brown BL
Insights into two modes of TdT action in human V(D)J recombination.
1. Trends Biochem Sci - published October 1, 2026
2. Delarue M, Lieber MR
Discovery of direct-acting small-molecule RIG-I agonists through creation of a selective CARD activation platform.
1. Nat Commun - published October 1, 2026
2. Guo R, Norford K, Xu L, Wei M, Wang W, Halene S, Pyle AM
ATP-driven dynamics and itraconazole binding of the drug efflux pump Cdr1 from Candida glabrata.
1. EMBO J - published October 1, 2026
2. Pata J, Wiseman B, Zarkadas E, Baccouch R, Samrouth N, Desbois C, Moissonier L, Moreno A, Banerjee A, Aguerro S, Bettler E, Dujardin M, Magnard S, Terreux R, Schoehn G, Högbom M, Boumendjel A, Lamping E, Cannon RD, Prasad R, Chaptal V, Falson P
Introduction: Insertion and Folding of Membrane Proteins and Peptides.
1. Chem Rev - published October 1, 2026
2. Booth PJ, Sanders CR
Molecular Characterisation of the Nuclear Localisation Sequence Binding Properties of Toxoplasma gondii Importin α.
1. Cells - published October 1, 2026
2. Mehta D, Banerjee B, Coulibaly F, Wagstaff KM, Patankar S, Bhaumik P, Jans DA
Structural basis of voltage gating in a partially activated K(+) channel.
1. Nat Commun - published October 1, 2026
2. Agrawal R, Mendoza Uriarte R, Pinto-Anwandter BI, Thomas T, Blachowicz L, Koh YH, Bezanilla F, Perozo E, Roux B