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36 Member Publications for February 2026

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Blind Challenges Let Us See the Path Forward for Predictive Models.
1. J Chem Inf Model - published February 6, 2026
2. Chodera JD, Walters WP, Kosuri S, Fraser JS
Therapeutic optimization of LIPA targeting to induce endoplasmic reticulum stress and cell death in ovarian cancer.
1. Oncogene - published February 6, 2026
2. Viswanadhapalli S, Lee TK, Elmore S, Sharma G, Gopalam R, Panneerdoss DM, Liu X, Parra K, Reese T, Hsieh M, Pratap UP, Yang X, Ebrahimi B, Li X, Neal H, Chen CY, Kassees K, Cervantes C, Baker A, Subbarayalu P, Ramirez P, Lyons YA, Lai Z, Chen Y, Boerma JW, LoCoco PM, Clanton NA, Xu Z, Rao M, Rao TR, Kost E, Sareddy GR, Raj GV, Ahn JM, Vadlamudi RK
Development of nanobody-conjugated LL37 for synergistic therapy against MDR Acinetobacter baumannii.
1. mSphere - published February 6, 2026
2. Thaiprayoon A, Oonanant W, Boonsilp S, Submunkongtawee N, Longsompurana P, Moonmangmee D, Riangrungroj P, Leelawattanachai J, Tabtimmai L, Kruse AC, DeLisa MP, Havanapan P-o, Waraho-Zhmayev D
Deposition of CENP-A Cse4 is enhanced by mutations in the AAA+ ATPase domain of ATAD2 Yta7.
1. Genetics - published February 5, 2026
2. Kaur N, Cho C, Samel-Pommerencke A, Shahnejat-Bushehri S, Poßling A, Kuznecova J, Song JJ, Ehrenhofer-Murray AE
Isolation and characterization of broadly-neutralizing anti-HCMV-gB antibodies from human donors using a prefusion-stabilized HCMV gB variant.
1. PLoS Pathog - published February 5, 2026
2. McClave MK, Wan YH, White EM, Gálvez Martínez B, Karimian Shamsabadi M, Aldridge N, Poudel B, Sperl AW, McGuire AT, Heldwein EE
Single-molecule tracking of DNMT1 in living cells reveals its cell cycle dynamics and its redistribution upon drug treatment.
1. Nucleic Acids Res - published February 5, 2026
2. Lee ES, Tommer ER, Rothman PB, Middleton SV, Youmans DT, Cech TR
Ligand Binding Dynamics of Ion Channels and GPCRs Using Single-Molecule Fluorescence.
1. Annu Rev Biophys - published February 5, 2026
2. Chowdhury SR, Goldsmith RH, Chanda B
Editorial: Molecular and physiological mechanisms driving phytoremediation.
1. Front Plant Sci - published February 5, 2026
2. Noori A, Sharifan H, Rodríguez-Seijo A
The interaction of XPG with TFIIH through p62 and XPD is required for the completion of nucleotide excision repair.
1. Nucleic Acids Res - published February 5, 2026
2. Kim M, Jeong E, Park J, D'Souza A, Tsai MS, Yan C, Ivanov I, Chazin WJ, Kim HS, Schärer OD
Programmable genome editing in human cells using RNA-guided bridge recombinases.
1. Science - published February 5, 2026
2. Pelea O, Tálas A, Carrera JF, Mathis N, van de Venn L, Yeh CD, Kulcsár PI, Marquart KF, Weber Y, Gerecke SE, Harvey-Seutcheu IF, Mailänder D, Pfleiderer MM, Chanez C, Corn JE, Schwank G, Jinek M
NMR, a tool for biology.
1. Structure - published February 5, 2026
2. Izadi-Pruneyre N, Nilges M
A multivalent adaptor mechanism drives the nuclear import of proteasomes.
1. Nat Commun - published February 4, 2026
2. Brunner HL, Kalis RW, Grundmann L, Hodáková Z, Koskova Z, Grishkovskaya I, de Almeida M, Hinterndorfer M, Knaudt H, Höfflin S, Andersch F, Kotisch H, Dickmanns A, Cuylen-Haering S, Zuber J, Haselbach D
Metabolic engineering of doxorubicin biosynthesis through P450-redox partner optimization and structural analysis of DoxA.
1. Nat Commun - published February 4, 2026
2. Koroleva A, Artukka E, Yamada K, Newmister SA, Harte RJ, Boesger H, Londen M, Sanders JN, Tirkkonen H, Kannisto M, Kuin RCM, Hulst M, Wang R, Leskinen E, Barillec M, Niemi J, van Wezel GP, Neefjes J, Nybo SE, Houk KN, Sherman DH, Kim RQ, Metsä-Ketelä M
Controlling spatial structure in minimal microbial communities by sequential capillary assembly.
1. Lab Chip - published February 4, 2026
2. Boggon C, Wong JPH, Sahoo A, Zinkernagel AS, Seeger MA, Secchi E, Isa L
KRAS4a and KRAS4b show distinct lipid-dependent regulation of RAS-RAF membrane dynamics.
1. J Biol Chem - published February 4, 2026
2. Georgouli K, Tempkin JOB, Stanton LG, Oppelstrup T, Shrestha R, Carpenter TS, Aydin F, Zhang X, Bhatia H, Yang Y, Van QN, Bonilla PA, Gulten G, Goswami D, Di Natale F, Chavez JR, Moon JY, Dharuman G, Hengartner NW, Simanshu DK, Tran TH, Nguyen K, Stanley CB, Van Essen B, Bremer PT, Lightstone FC, Stephen AG, Glosli JN, Gnanakaran S, Turbyville TJ, McCormick F, Nissley DV, Streitz FH, Ingólfsson HI
Coordination of cell organelles to promote metabolon formation.
1. Proc Natl Acad Sci U S A - published February 3, 2026
2. Sha Z, Pedley AM, Iles TD, Zhang S, Staub JR, Zhou R, Benkovic SJ
Intercalated bacterial biofilms are intrinsic internal components of calcium-based kidney stones.
1. Proc Natl Acad Sci U S A - published February 3, 2026
2. Schmidt WC, Mousavi A, Li J, Yang R, Gonzalez Marin G, Schreiber HL 4th, Hammann RES, Obernuefemann CLP, Bergeron K, Klim A, Wong D, Du K, Hultgren SJ, Chen Q, Celestian A, Wong GCL, Scotland KB
Integrated mutational landscape analysis of endometrial stromal sarcoma.
1. Proc Natl Acad Sci U S A - published February 3, 2026
2. Hartwich TMP, Choi S, Hwang A, Bellone S, Palmieri L, Seo H, Kim T, Hong J, Krakstad C, Trovik J, Stefansson IM, Haugland HK, Greenman M, Ettorre V, Ottum S, Demirkiran C, Yang-Hartwich Y, Buza N, Hui P, Lopez S, Cormio G, Ramunno M, Zito A, Perrone E, Fagotti A, Fanfani F, Santoro A, Ravaggi A, Bignotti E, Odicino F, Ardighieri L, Ratner E, Angioli R, Perrone G, Luvero D, Conca B, Choi J, Schlessinger J, Santin AD
The BK channel-NS1619 agonist complex reveals molecular insights into allosteric activation gating.
1. Proc Natl Acad Sci U S A - published February 3, 2026
2. Gonzalez-Sanabria N, Contreras GF, Rojas M, Duarte Y, Gonzalez-Nilo FD, Perozo E, Latorre R
Recurrent resistance mutations to lirafugratinib inform treatment sequencing in FGFR2-driven tumors.
1. Clin Cancer Res - published February 3, 2026
2. Facchinetti F, Hollebecque A, Barbé R, Jang DM, Alonso-De-Castro B, Brayé F, Bigot L, Nobre C, Da Silva A, Méteau M, Delavigne M, Soares M, Italiano A, Rodriguez J, Mosele F, Beshiri K, Ducreux M, Boilève A, Nikolaev S, Alonso-Garcia I, Vasseur D, Smolenschi C, Bourien H, Cotteret S, Samaniego J, Bernard E, Nicotra C, Ngo-Camus M, Nakazawa S, Tselikas L, Badoual C, André F, Eck MJ, Olaussen KA, Loriot Y, Friboulet L
Identification of a potent V3 glycan site broadly neutralizing antibody targeting an N332(gp120) glycan-independent epitope.
1. Nat Immunol - published February 3, 2026
2. Gieselmann L, DeLaitsch AT, Rohde M, Radford C, Worczinski J, Ashurov A, Ahmadov E, Burger JA, Havenar-Daughton C, Deshpande S, Giovannoni F, Corti D, Kreer C, Ercanoglu MS, Schommers P, Georgiev IS, West AP Jr, Knüfer J, Stumpf R, Kroidl A, Geldmacher C, Maganga L, William W, Ntinginya NE, Hoelscher M, Yang Z, Wei Q, Renfrow MB, Green TJ, Novak J, van Gils MJ, Gristick HB, Gruell H, Bloom JD, Seaman MS, Bjorkman PJ, Klein F
Author Correction: The human ciliopathy protein RSG1 links the CPLANE complex to transition zone architecture.
1. Nat Commun - published February 2, 2026
2. Vazquez N, Lee C, Valenzuela I, Phan TP, Derderian C, Chávez M, Mooney NA, Demeter J, Aziz-Zanjani MO, Cusco I, Codina M, Martínez-Gil N, Valverde D, Solarat C, Bruel AL, Thauvin-Robinet C, Steichen E, Filges I, Joset P, De Geyter J, Vaidyanathan K, Gardner TP, Toriyama M, Marcotte EM, Drew K, Roberson EC, Jackson PK, Reiter JF, Tizzano EF, Wallingford JB
Mechanistic insights and in vivo HIV suppression by the BRD4-targeting small molecule ZL0580.
1. PLoS Pathog - published February 2, 2026
2. Kumar N, Ma Z, Long F, Bonam SR, Lai HT, Wu SY, Chen H, Hazell NC, Bei J, Liu X, Chen Y, Wei Z, Chiang CM, Zhou J, Hu H
ER remodelling is a feature of ageing and depends on ER-phagy.
1. Nat Cell Biol - published February 2, 2026
2. Donahue EKF, Hepowit NL, Ruark EM, Mulligan AG, Keuchel B, Urban ND, Peng L, Stephens S, Johnson DJ, Wallace NS, Jackson LP, Ellisman MH, Arrojo E Drigo R, Folkmann AW, Truttmann MC, MacGurn JA, Burkewitz K
Regulation of tension-dependent localization of LATS1 and LATS2 to adherens junctions.
1. PLoS One - published February 2, 2026
2. De Silva C, Kelch BA, McCollum D
The CspC:CspA heterodimer transduces germinant and co-germinant signals during Clostridioides difficile spore germination.
1. PLoS Biol - published February 2, 2026
2. McNellis ME, González-Del Pino G, Serrano-Jiménez JA, Forster ER, Stoica AI, Heldwein EE, Shen A
Cytochrome nanowires under electron microscopy.
1. Emerg Top Life Sci - published February 2, 2026
2. Petersen HA, Hochbaum AI, Bond DR, Wang F
Electromotility can be disassociated from gating charge movement in outer hair cells of conditional alpha2 spectrin knockout mice.
1. J Biol Chem - published February 2, 2026
2. Bai JP, Stankewich MC, Yang J, Tan W, Zuo Z, Song Q, Khan S, Wang L, Morrow JS, Santos-Sacchi J, Navaratnam DS
HYPK-Related Neurodevelopmental Syndrome: Case Report of Intellectual Disability, Developmental Delay, and Dysmorphic Features.
1. Clin Genet - published February 1, 2026
2. Patel R, Makwana R, Marchi E, Fan Z, Falsey E, Menendez B, Giampietro P, Wentzensen IM, Hsieh TC, Shan SO, Lyon GJ
Polyphyletic screen defines distinct classes of plant-derived natural products that oppose tauopathy.
1. Life Sci Alliance - published February 1, 2026
2. Shepard CD, Chang X, Seidler PM, Curran SP
Sample purification and characterization of the α- and β-crustacyanin pigments from the American lobster for crystallographic and cryo-EM studies.
1. Acta Crystallogr F Struct Biol Commun - published February 1, 2026
2. Cedri MC, Bansia H, Amici A, Collet T, Moretti P, McCarthy AA, Mueller-Dieckmann C, Raffaelli N, Wang T, des Georges A, Cianci M
Cryo-EM reveals an ensemble of cytochrome P450 reductase conformations in solution.
1. Protein Sci - published February 1, 2026
2. Lepesheva GI, Hargrove TY, Ren Y
Guiding AlphaFold predictions with experimental knowledge to inform dynamics and interactions with VAIRO.
1. Protein Sci - published February 1, 2026
2. Triviño J, Jiménez E, Grininger C, Caballero I, Medina A, Castellví A, Petrillo G, Govantes F, Sagmeister T, Alcorlo M, Hermoso JA, Sammito MD, Diederichs K, Pavkov-Keller T, Usón I
Case Series of Histopathological Findings in Chronic Kidney Disease: Insights From the Kidney Precision Medicine Project.
1. Kidney Med - published February 1, 2026
2. Limonte CP, Aw S, Alpers CE, Barisoni L, Berry B, Brosius FC, Campbell KN, Herlitz LC, Laszik Z, McMahon G, Mottl A, Nachman P, Nam Y, Poggio EE, Randhawa PS, Rosas SE, Stillman IE, Taliercio JJ, Torrealba J, Tuttle K, Vazquez M, de Boer IH, Henderson J, Kidney Precision Medicine Project
ADAM15 Is a Potential Biomarker for Pan-Cancer Prognosis and Immunotherapy: Validation in HCC and COAD.
1. IUBMB Life - published February 1, 2026
2. Guo W, Liu Y, Ma W, Fan L, Chen B, Wang J
Genomic and Effector-Based Insights Into Austropuccinia psidii-Host Interactions Informing RNAi and Resistance Development.
1. Mol Plant Pathol - published February 1, 2026
2. Sullivan JV, Eccersall SE, Smith GR, Dobson RCJ, Meisrimler CN