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123 Member Publications for October 2025

Meeting Summary for Keystone Symposia on HIV Cure: Antiretroviral Therapy (ART)-Free Control of HIV Infection in Durban, South Africa, 2025.
1. Pathog Immun - published October 27, 2025
2. Tanaka K, Chikowore TJB, Deeks SG, Estes JD, Ho YC, Jiang S, Lee MJ, Li C, Machinda A, Martins M, Mdletshe P, Ndhlovu ZM, Neogi U, Ott MM, Rasmussen TA, Reddy K, Rutishauser RL, Farrell-Sherman A, Tiemessen CT, Voss JE, Kityo C, Lewin SR, Ndung'u T, McCune JM
Multi-omics analysis reveals Angelica dahurica radix extract alleviates migraine in rats via gut microbiota-metabolome-gut-brain axis regulation.
1. Front Pharmacol - published October 24, 2025
2. Lian Y, Gan Z, Sun J, Zhao J, Li Q, Shen X, Xue M, Li J, Luo J, Liu X, Feng W, Jiang G
Author Correction: A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas.
1. Nat Commun - published October 9, 2025
2. Apfelbaum AA, Morin E, Sturm D, Ayoub G, DiGiacomo J, Bahadur S, Chandarana B, Power PC, Cusick MM, Novikov D, Prabhakar P, Jones RE, Vogelzang J, Bossi CC, Malinowski S, Woodward LM, Jones TA, Jeang J, Lamson SW, Collins J, Cai KY, Jones JS, Oh S, Jeon H, Wang J, Cameron A, Rechter P, De Leon A, Murugesan K, Montesion M, Albacker LA, Ramkissoon SH, van Tilburg CM, Hardin EC, Sievers P, Sahm F, Yeo KK, Rosenberg T, Chi SN, Wright KD, Hébert S, Peck S, Picca A, Larouche V, Renzi S, Buhrlage SJ, Bale TA, Smith AA, Touat M, Jabado N, Fischer ES, Eck MJ, Baird L, Witt O, Kleinman CL, Nguyen QD, Sheer D, Alexandrescu S, Jones DTW, Ligon KL, Bandopadhayay P
Protein Target Highlights in CASP16: Insights From the Structure Providers.
1. Proteins - published October 9, 2025
2. Alexander LT, Follonier OM, Kryshtafovych A, Abesamis K, Bibi-Triki S, Box HG, Breyton C, Bringel F, Carrique L, d'Acapito A, Dong G, DuBois R, Fass D, Fiesco JM, Fox DR, Grimes JM, Grinter R, Jenkins M, Kamyshinsky R, Keown JR, Lackner G, Lammers M, Liu S, Lovering AL, Malinauskas T, Masquida B, Palm GJ, Siebold C, Su T, Zhang P, Zhou ZH, Fidelis K, Topf M, Moult J, Schwede T
Visualization of Trypanosoma brucei flagellar pocket collar biogenesis identifies two new cytoskeletal structures.
1. PLoS Biol - published October 9, 2025
2. Zelená M, Casas E, Lambert C, Landrein N, Dacheux D, Bertiaux E, Abesamis KI, Dong G, Varga V, Robinson DR, Bonhivers M
Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity.
1. Immunity - published October 9, 2025
2. Bekkering ET, Yoo R, Hailemariam S, Heide F, Ivanochko D, Jackman M, Proellochs NI, Stoter R, van Gemert GJ, Maeda A, Yuguchi T, Wanders OT, van Daalen RC, Inklaar MR, Andrade CM, Jansen PWTC, Vermeulen M, Bousema T, Takashima E, Rubinstein JL, Kooij TWA, Jore MM, Julien JP
A few-shot u-net learning framework for fast and accurate three-dimensional dose prediction in radiotherapy.
1. Phys Med - published October 9, 2025
2. Chen Z, Li W, Shen X, Chen RC, Lin Y, Gao H
Temporal regulation of signal recognition particle during translation.
1. J Mol Biol - published October 9, 2025
2. Qian R, Gora RJ, Chandrasekar S, Shan SO
Viral metagenomic sequencing reveals rare pathogens and improves diagnostic accuracy in neuroinflammatory disorders.
1. Diagn Microbiol Infect Dis - published October 9, 2025
2. Pichler I, Krischer E, Obenhuber T, Hirsch B, Reinhold I, Wiedmer C, Ziltener G, Weller D, Roth P, Weiss T, Kufner V, Bloemberg GV, Trkola A, Müller NJ, Huber M
Production of Clinical-Grade SARS-CoV-2 Spike Ferritin Nanoparticle Protein Immunogen by Transient Transfection.
1. Vaccines (Basel) - published October 9, 2025
2. Hajduczki A, Chang WC, De La Barrera R, Wood JF, Chen WH, Martinez EJ, Jensen JL, Sankhala RS, Smith C, Anderson A, Morrison EB, Peterson CE, Rees PA, Soman S, Kuklis C, Ahmed A, King J, Nasar F, Corbitt C, Choe M, Thomas PV, Zemil M, Wieczorek L, Polonis VR, Dooley HM, Mascola JR, de Val N, Matyas GR, Rao M, Gromowski GD, Modjarrad K, Vasan S, Froude JW, Michael NL, Joyce MG, Zarling S
Characterization and inhibitor sensitivity of ARAF, BRAF, and CRAF kinases.
1. J Biol Chem - published October 8, 2025
2. Tkacik E, Jang DM, Boxer K, Ha BH, Eck MJ
Nickel Binding to the c-Src SH3 Domain Facilitates Crystallization.
1. Protein Pept Lett - published October 8, 2025
2. Calicdan X, Fisher OS, Ha BH, Boggon TJ, Stiegler AL
Mechanistic Interrogation of a PQQ and Rare Earth-Dependent Artificial Metalloenzyme.
1. J Am Chem Soc - published October 7, 2025
2. Taher M, Thompson PJ, Nava-Matadamas C, Bruchs AT, Bridwell-Rabb J, Olshansky L
Separation of Pseudomonas aeruginosa type IV pilus-dependent twitching motility and surface-sensing responses.
1. mBio - published October 7, 2025
2. Barnshaw R, Harvey H, McCallum M, Lazarou T, Nguyen S, Qaderi I, Tran V, Roberge N, Geiger C, O'Toole GA, Howell PL, Burrows LL
Defective Notch1 signaling in endothelial cells drives pathogenesis in a mouse model of Adams-Oliver Syndrome.
1. J Clin Invest - published October 7, 2025
2. Solano AF, Preusse K, Cain B, Hotz R, Gavini P, Yuan Z, Bowen B, Maco G, Neal H, Gagliani EK, Ahn C, Lim HW, Southgate L, Kovall RA, Kopan R, Gebelein B
Repertoire, function, and structure of serological antibodies induced by the R21/Matrix-M malaria vaccine.
1. J Exp Med - published October 6, 2025
2. McDaniel JR, Voss WN, Bowyer G, Rush SA, Spencer AJ, Bellamy D, Ulaszewska M, Goike J, Gregory S, King CR, McLellan JS, Hill AVS, Georgiou G, Ewer KJ, Ippolito GC
Design and characterization of HIV-1 vaccine candidates to elicit antibodies targeting multiple epitopes.
1. J Exp Med - published October 6, 2025
2. Gristick HB, Hartweger H, Nishimura Y, Gavor E, Nagashima K, Koranda NS, Gnanapragasam PNP, Kakutani LM, Segovia LN, Donau OK, Keeffe JR, West AP Jr, Martin MA, Nussenzweig MC, Bjorkman PJ
Profiling of HIV-1 elite neutralizer cohort reveals a CD4bs bnAb for HIV-1 prevention and therapy.
1. Nat Immunol - published October 6, 2025
2. Gieselmann L, DeLaitsch AT, Rohde M, Gruell H, Kreer C, Ercanoglu MS, Gristick HB, Schommers P, Ahmadov E, Radford C, Mazzolini A, Zhang L, West AP Jr, Worczinski J, Momot A, Reichwein ML, Knüfer J, Stumpf R, Mkhize NN, Kaldine H, Bhebhe S, Deshpande S, Giovannoni F, Stefanutti E, Benigni F, Havenar-Daughton C, Corti D, Kroidl A, Adhikari A, Nanfack AJ, Ambada GE, Duerr R, Maganga L, William W, Ntinginya NE, Wolf T, Geldmacher C, Hoelscher M, Lehmann C, Moore PL, Mora T, Walczak AM, Gilbert PB, Doria-Rose NA, Huang Y, Bloom JD, Seaman MS, Bjorkman PJ, Klein F
A novel lncRNA FAM151B-DT regulates degradation of aggregation prone proteins.
1. Mol Psychiatry - published October 6, 2025
2. Renganathan A, Minaya MA, Broder M, Alfradique-Dunham I, Miller RL, Dhavale DD, Moritz M, Bhagat R, Marsh J, Verbeck A, Galasso G, Starr E, Agard DA, Kotzbauer PT, Cruchaga C, Karch CM
Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal SARS-CoV-2 antagonist.
1. Commun Biol - published October 6, 2025
2. Gonzales J, Young T, Choi H, Park M, Jewel Y, Fan C, Purohit R, Bjorkman PJ, Williams JC
Atg2/TRAPPIII-Ypt1 axis: deciphering the phagophore-ERES connection.
1. Autophagy - published October 6, 2025
2. Gómez-Sánchez R, Fromme JC, Ungermann C, Reggiori F
Redox Partner Adrenodoxin Induces Substrate Binding to Steroidogenic Cytochrome P450 11B2 and 11A1 by Promoting A Conformational Change.
1. J Biol Chem - published October 6, 2025
2. Loomis CL, Redhair M, Im SC, Scott EE
Antimicrobial applications of amphiphilic gold nanoparticles for antibiotic delivery.
1. J Mater Chem B - published October 3, 2025
2. Yedavally H, Gasbarri M, van Dijl JM, Stellacci F, Salvati A
Human RPA is an essential telomerase processivity factor for maintaining telomeres.
1. Science - published October 3, 2025
2. Agrawal S, Lin X, Susvirkar V, O'Connor MS, Chavez BL, Tholkes VR, Tauber GP, He Q, Abe KM, Huang X, Lim CJ
Toxoplasma effector TgWIP hijacks dendritic cell actin and motility via Nck1/Grb2 and the WAVE complex.
1. mBio - published October 3, 2025
2. Morales P, Kramer DA, de Moraes de Siqueira C, Brown AJ, Sangaré LO, Chen B, Saeij JPJ
Glutamine synthetase deficiency enhances CD8 T cell survival and stress resilience in the tumor microenvironment.
1. J Immunol - published October 3, 2025
2. Fisher-Gupta EL, Hathaway ES, Perera JM, Jennings EQ, Chi C, Sewell AE, Stone SH, Muka JE, Sinard RC, DeCorte JA, Chen H, Wilson JT, Meiler J, Rathmell JC
A single-nucleus transcriptomic atlas of the adult Aedes aegypti mosquito.
1. Cell - published October 3, 2025
2. Goldman OV, DeFoe AE, Qi Y, Jiao Y, Weng SC, Wick B, Houri-Zeevi L, Lakhiani P, Morita T, Razzauti J, Rosas-Villegas A, Tsitohay YN, Walker MM, Hopkins BR, Aedes aegypti Mosquito Cell Atlas Consortium, Haeussler M, Akbari OS, Duvall LB, White-Cooper H, Sorrells TR, Sharma R, Li H, Vosshall LB, Shai N
Molecular interactions of the Na(V)1.5 C-terminal domain: CaM sequestered the IQ motif from the CTD.
1. J Biol Chem - published October 3, 2025
2. Gyawu RF, Beard TM, Tikunova S, Ulker A, Garcia SA, Knotts GM, Agee TA, Alam Afsar MN, Kroncke B, Smith J, Davis J, Johnson CN
Integrative brain omics approach highlights sn-1 lysophosphatidylethanolamine in Alzheimer's dementia.
1. Nat Commun - published October 3, 2025
2. Chen CY, Maner-Smith K, Khadka M, Ahn J, Gulbin XL, Ivanova AA, Dammer EB, Seyfried NT, Bennett DA, Hajjar IM, Ortlund EA
Structural landscape of activation, desensitization and inhibition in the human TRPM4 channel.
1. Nat Struct Mol Biol - published October 3, 2025
2. Teixeira-Duarte CM, Zeng W, Jiang Y
Adapting health, economic and social policies to address population aging in China.
1. Nat Aging - published October 3, 2025
2. Fang EF, Fang Y, Chen G, Wang HL, Zhang J, Wu C, Liao J, Xie C, Liu X, Wang K, Liu Y, Yang G, Wang Q, He LT, Li J, Chen HZ, Kang L, Jiang Y, Su H, Jiang H, He N, Tao J, Leng SX, Siow RC, Liu C, Khan HTA, Liu Y, Kato H, Sasaki T, Kim JI, Maier AB, Zhang L, Rasmussen LJ, Woo J, Wu J, Zou H
Electrostatic changes enabled the diversification of an exocyst subunit via protein complex escape.
1. Nat Plants - published October 3, 2025
2. De la Concepcion JC, Duverge H, Kim Y, Julian J, Xu HD, Watt MN, Ikene SA, Bianchi A, Grujic N, Papareddy RK, Grishkovskaya I, Haselbach D, Murray DH, Clavel M, Irwin NAT, Dagdas Y
RNF114, a RING E3 ligase that reads and extends the hybrid ADP-ribose-ubiquitin signal.
1. EMBO J - published October 2, 2025
2. Middleton AJ, Day CL
Asynchronous subunit transitions prime acetylcholine receptor activation.
1. Science - published October 2, 2025
2. Thompson MJ, Tessier CJG, Ananchenko A, Hénault C, Emlaw JR, Dehez F, Zarkadas E, daCosta CJB, Nury H, Baenziger JE
Integrated flavoromics and lipidomics analysis of metabolic difference and flavor regulation mechanisms in duck subcutaneous adipose tissue.
1. Front Nutr - published October 2, 2025
2. Gong P, Cheng S, Chen X, Wang L, Wang Y, Zhai M, Qian Y, Ye S, Yang Y
GCN1 couples GCN2 to ribosomal state to initiate amino acid response pathway signaling.
1. Science - published October 2, 2025
2. Zhou C, Zhang M, Murray J, Paulo J, Gygi S, Shao S, Whitman M, Keller T
Publisher Correction: Multimodal cell maps as a foundation for structural and functional genomics.
1. Nature - published October 2, 2025
2. Schaffer LV, Hu M, Qian G, Moon KM, Pal A, Soni N, Latham AP, Pontano Vaites L, Tsai D, Mattson NM, Licon K, Bachelder R, Cesnik A, Gaur I, Le T, Leineweber W, Palar A, Pulido E, Qin Y, Zhao X, Churas C, Lenkiewicz J, Chen J, Ono K, Pratt D, Zage P, Echeverria I, Sali A, Harper JW, Gygi SP, Foster LJ, Huttlin EL, Lundberg E, Ideker T
A needed nomenclature for nucleosomes.
1. Mol Cell - published October 2, 2025
2. Keogh MC, Almouzni G, Andrews AJ, Armache KJ, Arrowsmith CH, Baek SH, Bedford MT, Bernstein E, Côté J, David Y, Denu JM, Fierz B, Garcia BA, Glass KC, Gozani O, Helin K, Henikoff S, Jensen ON, Josefowicz SZ, Kelleher NL, Kutateladze TG, Lindner HH, Lu C, Luger K, Mallick P, Musselman CA, Muir TW, Paša-Tolić L, Schneider R, Shi X, Shi Y, Sidoli S, Smith LM, Tyler JK, Wolberger C, Workman JL, Strahl BD, Young NL
Small-molecule allosteric activator of ubiquitin-specific protease 7 (USP7).
1. Proc Natl Acad Sci U S A - published October 2, 2025
2. Jaen Maisonet I, Sharafi M, Korchak EJ, Salazar-Chaparro A, Bratt AS, Parikh T, Varca AC, Shah B, Darnowski M, Chung M, Teh WP, Che J, Bezsonova I, Buhrlage SJ
Integrative mapping reveals molecular features underlying the mechanism of nucleocytoplasmic transport.
1. Proc Natl Acad Sci U S A - published October 2, 2025
2. Raveh B, Eliasian R, Rashkovits S, Russel D, Hayama R, Sparks S, Singh D, Lim RYH, Villa E, Rout MP, Cowburn D, Sali A
Endogenous structure of antimalarial target PfATP4 reveals an apicomplexan-specific P-type ATPase modulator.
1. Nat Commun - published October 2, 2025
2. Haile MT, Shukla A, Zhen J, Mather MW, Bhatnagar S, Morrisey JM, Zhang Z, Vaidya AB, Ho CM
Global analysis of translocon remodeling during protein synthesis at the ER.
1. Nat Struct Mol Biol - published October 2, 2025
2. Sundaram A, Li Q, Wan Y, Tang J, Wu H, Smalinskaitė L, Hegde RS, Ji Z, Keenan RJ
Erythrocytosis-inducing PHD2 mutations implicate biological role for N-terminal prolyl-hydroxylation in HIF1α oxygen-dependent degradation domain.
1. Elife - published October 2, 2025
2. Taber CC, He W, Gasmi-Seabrook GMC, Hubert M, Ferens FG, Ikura M, Lee JE, Ohh M
A Three-Component Path to Amino Thiadiazoles and Amino Oxadiazoles via a Nitrilium Ylide.
1. J Org Chem - published October 2, 2025
2. Bastick KAC, Diamandas M, Ou YD, Huang BZ, Yudin AK
Therapeutic IgG- and IgM-specific proteases disarm the acetylcholine receptor autoantibodies that drive myasthenia gravis pathology.
1. Proc Natl Acad Sci U S A - published October 2, 2025
2. Bayer AC, Sanmarco LM, Pellerin A, Masi G, Plasencia A, Anderson JM, Nowak RJ, Damato V, Massacesi L, Pham MC, Khani-Habibabadi F, Vital H, Higginson-Scott N, Otipoby KL, Xing Y, Mascanfroni ID, O'Connor KC
CryoDataBot: a pipeline to curate cryoEM datasets for AI-driven structural biology.
1. Gigascience - published October 2, 2025
2. Xu Q, Wu L, Rebelo M, Feng S, Yu X, Farheen F, Kihara D, Zhou ZH
ClpC1 Modulating Ohmyungsamycin A and Ecumicin Natural Product Analogues are Potent Antimycobacterials.
1. ACS Infect Dis - published October 2, 2025
2. Hawkins PME, Bedding MJ, Hoi DM, Barter IK, Cheung CY, Oehlers SH, Cook GM, Clausen T, Britton WJ, Payne RJ
Structural mechanisms of assembly, gating, and calmodulin modulation of human olfactory CNG channel.
1. Nat Commun - published October 2, 2025
2. Xue J, Gan N, Zeng W, Jiang Y
Epitope Mapping of Diagnostic Antibodies Targeting SARS-CoV-2 Nucleocapsid Protein Using Hydrogen-Deuterium Exchange Mass Spectrometry.
1. Biophys J - published October 2, 2025
2. Nazaar SM, Jain A, Liu X, Platt ME, Roberts AM, Frank F, Ortlund EA, Lam WA, Roberts BR
Synthesis and Biophysical Properties of 3'-Deoxy-β-d-apio-d-furanosyl Nucleic Acids.
1. ACS Chem Biol - published October 2, 2025
2. Jauregui-Matos V, Datta D, Kundu J, Kumar V, Harp JM, Adebayo A, Donnelly D, Medina E, Chaput JC, Egli M, Manoharan M
Paf1C regulates the Neurospora circadian clock by promoting the transcription elongation of frequency.
1. PLoS Genet - published October 2, 2025
2. Zhou M, Zhao Y, He Y, Duan Z, Liu X, He Q
Structural Insights and Functional Dynamics of β-Lactoglobulin Fibrils.
1. Nano Lett - published October 2, 2025
2. Sternke-Hoffmann R, Rhyner D, Terashi G, Qureshi BM, Riek R, Greenwald J, Kihara D, Lutz-Bueno V, Luo J
Transdiagnostic alterations in white matter microstructure associated with suicidal thoughts and behaviours in the ENIGMA Suicidal Thoughts and Behaviours consortium.
1. Transl Psychiatry - published October 2, 2025
2. van Velzen LS, Colic L, Ceja Z, Dauvermann MR, Villa LM, Savage HS, Toenders YJ, Dehestani N, Zhu AH, Campos AI, Salminen LE, Alda M, Agartz I, Alexander N, Ayesa-Arriola R, Ballard ED, Banaj N, Barkhau C, Başgöze Z, Bauer J, Benedetti F, Berger K, Besteher B, Brosch K, Canal-Rivero M, Cervenka S, Colle R, Connolly CG, Corruble E, Courtet P, Couvy-Duchesne B, Crespo-Facorro B, Cullen KR, Dannlowski U, Deverdun J, Diaz-Zuluaga AM, Dietze LMF, Evans JW, Fani N, Flinkenflügel K, Friedman NP, Gotlib IH, Groenewold NA, Grotegerd D, Hajek T, Hatoum AS, Hermesdorf M, Hickie IB, Hirano Y, Ho TC, Ikemizu Y, Iorfino F, Ipser JC, Isobe Y, Jackowski AP, Jollant F, Kircher T, Klug M, Koopowitz SM, Kraus A, Krug A, Le Bars E, Leehr EJ, Li M, Lippard ETC, Lopez-Jaramillo C, Maximov II, McIntosh AM, McLaughlin KA, McWhinney SR, Meinert S, Melloni E, Mitchell PB, Mwangi B, Nenadić I, Nerland S, Olie E, Ortiz-García de la Foz V, Pan PM, Pereira F, Piras F, Piras F, Poletti S, Reineberg AE, Roberts G, Romero-García R, Sacchet MD, Salum GA, Sandu AL, Sellgren CM, Shimizu E, Smolker HR, Soares JC, Steele JD, Stein F, Stein DJ, Straube B, Teutenberg L, Thomas-Odenthal F, Usemann P, Valabregue R, Valencia-Echeverry J, Wagner G, Waiter G, Walter M, Whalley HC, Wu MJ, Yang TT, Zarate CA, Zugman A, Zunta-Soares GB, van Heeringen K, van Rooij SJH, van der Wee N, van der Werff S, Thompson PM, Blumberg HP, van Harmelen AL, Rentería ME, Jahanshad N, ENIGMA Suicidal Thoughts and Behaviours Consortium, Schmaal L
Sexually Distinct Multi-Omic Responses to Progressive Endurance Exercise Training in the Rat Lung - Findings from MoTrPAC.
1. Am J Respir Cell Mol Biol - published October 2, 2025
2. Many GM, Sagendorf TJ, Mitchell H, Sanford JA, Cohen S, Misra R, Estevao I, Díaz Ludovico I, Gaul DA, Lindholm ME, Ushakumary MG, Pino J, Musi N, Nie J, Fernández FM, Ortlund EA, Esser KA, Bodine SC, Schenk S, Clair G, Adkins JN, MoTrPAC Study Group
International expert consensus on gene therapy for hereditary hearing loss: Based on clinical trials.
1. Med - published October 2, 2025
2. Fan X, Gao Z, Zhong J, Chen Y, Chen X, Landegger LD, Moser T, Zeng FG, Sun Y, Jin X, Nash R, Chien WW, Jiang D, Greinwald JH, Bance M, Rodríguez MM, Lee SY, Feng G, Yang H, Wu CC, Xu L, Yuan W, Feng Y, Zhao Y, Vona B, Strenzke N, Beutner D, Amin N, Arwyn-Jones J, Chandrasekeharan D, Shi D, Zhang D, Yang J, Qi J, Wang Q, Yin Y, Cheng YF, Tao Y, Yu Y, Wang D, Jiang L, Guo L, Chen L, Cheng X, Cui C, Lv J, Han S, Wang W, Li Y, Gao X, Liu XZ, Zha D, Shi H, Chen B, Wang Q, Yuan H, Yang S, Yin S, Wu H, Wang Z, Li H, Rubinstein JT, Lustig LR, Chai R, Chen ZY, Shu Y
Establishing Selectivity Trends with Reactions of Thioesterases and Semi-Synthetic Polyketides.
1. J Am Chem Soc - published October 2, 2025
2. Litman ZC, Chen Y, Sherman DH
Bacterial TIR-based immune systems sense phage capsids to initiate defense.
1. Nat Microbiol - published October 2, 2025
2. Roberts CG, Fishman CB, Zhang Z, Banh DV, Patel DJ, Marraffini LA
Structure of nanobody-inhibited state of human bile salt transporter NTCP.
1. Structure - published October 2, 2025
2. Yoon D, Nosol K, Rasouli A, Bang-Sørensen R, Irobalieva RN, Liu H, Tajkhorshid E, Locher KP
Subtle changes in ligand-receptor interactions dramatically alter transcriptional outcomes of pregnane X receptor modulators.
1. Structure - published October 2, 2025
2. Huber AD, Garcia-Maldonado E, Lin W, Poudel S, Wu J, Miller DJ, Chen T
Efficient circRNA Detection Using the Processive Reverse Transcriptase uMRT.
1. Bio Protoc - published October 2, 2025
2. Warkentin R, Pyle AM
Conformational Quenching in an Engineered Lipocalin Protein Achieves High Affinity Binding to the Toxin Colchicine.
1. Angew Chem Int Ed Engl - published October 2, 2025
2. Bostock MJ, Kolloff C, Jerschke E, Asami S, Skerra A, Olsson S, Sattler M
Structures of vesicular stomatitis virus glycoprotein G alone and bound to a neutralizing antibody.
1. PLoS Pathog - published October 2, 2025
2. Minoves M, Ouldali M, Belot L, Roche S, Johari S, Noiray M, Zarkadas E, Schoehn G, Gaudin Y, Albertini AA
Structural basis of drug recognition by human MATE1 transporter.
1. Nat Commun - published October 2, 2025
2. Romane K, Peteani G, Mukherjee S, Kowal J, Rossi L, Hou J, Kossiakoff AA, Lemmin T, Locher KP
A Comparative Study of Virucidal and Virustatic Multivalent Entry Inhibitors.
1. J Phys Chem B - published October 2, 2025
2. Tran HT, Pawar S, Zhu Y, Ong QK, Stellacci F
Exploring Metalloproteome Remodeling in Calprotectin-Stressed Acinetobacter baumannii Using Chemoproteomics.
1. ACS Chem Biol - published October 2, 2025
2. Osterberg MK, Bak DW, Andreini C, Kim M, Critchlow JM, Trinidad JC, Cornish PV, Akizuki T, Chazin WJ, Skaar EP, Weerapana E, Giedroc DP
Optimization of Species-Selective Reversible Proteasome Inhibitors for the Treatment of Malaria.
1. J Med Chem - published October 2, 2025
2. Gahalawat S, Ray S, Zhang X, Deng X, Han Y, Chen Z, Lawong A, Shackleford DM, Katneni K, Chen G, Li P, Ng A, Zhong L, Hu M, McInerney M, Wang W, Saunders J, Collins D, Jayaseelan J, Noack CL, C Maity B, De N, Laleu B, Campbell SF, Phillips MA, Charman SA, Ready JM
A rapidly evolving female-controlled lock-and-key mechanism determines Aedes mosquito mating success.
1. Curr Biol - published October 2, 2025
2. Houri-Zeevi L, Walker MM, Razzauti J, Sharma A, Pasolli HA, Vosshall LB
A single-chain derivative of an integrin-activating antibody potentiates organoid growth in Matrigel and collagen hydrogels.
1. Nat Biotechnol - published October 2, 2025
2. de Lau WBM, Wijnakker JJAPM, van Son GJF, Krueger D, Wang D, Abendroth MS, Schreurs R, Janda CY, van Rijt FLH, Chalopin BJP, Bokobza E, van Es JH, Springer TA, Sonnenberg A, Clevers H
Allosteric inhibition of JAK2 with lysine-reactive compounds that bind the pseudokinase domain.
1. Eur J Med Chem - published October 2, 2025
2. Primi MC, Tavares MT, Hatcher JM, Kang H, Kresina TAC, Chakraborty S, Leroy E, Schmoker AM, Jeon H, Weisberg EL, Akatsu T, Griffin JD, Scott DA, Eck MJ
Multiple LDLR family members act as entry receptors for yellow fever virus.
1. Nature - published October 2, 2025
2. Chong Z, Hui S, Qiu X, Palakurty S, Sariol A, Kaszuba T, Nguyen MN, Li P, Raju S, Hall PD, Nelson CA, Baltazar-Perez I, Price DA, Rothlauf PW, Crowe JE, Whelan SPJ, Leung DW, Amarasinghe GK, Bailey AL, Fremont DH, Diamond MS
Functional and structural analyses of UbcH5 mutants with enhanced binding to the E3 ubiquitin ligase CHIP.
1. Biochem Biophys Res Commun - published October 2, 2025
2. Manage MM, Nix JC, Page RC
The congenital APOA1 K107del mutation disrupts the lipid-free conformation of monomeric APOA1 and impairs oligomerization.
1. J Lipid Res - published October 2, 2025
2. Ludovico ID, Gonzalez MC, Garda HA, Vázquez RF, Maté S, Tricerri MA, Ramella NA, Bedi S, Morris J, Street SE, Geh E, Clair GC, Davidson WS, Melchior JT
Molecular basis of vesicular monoamine transport and neurological drug interactions.
1. Cell Rep - published October 2, 2025
2. Ye J, Chen H, Ammerman A, Wang Y, Wang K, Xu J, Liu B, Li W
The AP-4 accessory protein tepsin exhibits multivalent binding to LC3B.
1. Adv Biol Regul - published October 2, 2025
2. Cohen CI, Kendall AK, Wallace NS, McCorkle ML, Jackson LP
Advancing the antituberculosis activity of nitropicolinic acids and amides.
1. Eur J Med Chem - published October 2, 2025
2. Thompson AM, Cheung CY, McNeil MB, Campbell AC, Záhorszká M, Korduláková J, Stelitano G, Recchia D, Pasca MR, Wan B, Khan S, Nikolic DS, Shetye GS, Franzblau SG, Denny WA, Cook GM, Krause KL
Histone PARylation factor 1: a review of its role in the DNA damage response.
1. Nucleic Acids Res - published October 2, 2025
2. Rudolph J, Luger K
Mei5-Sae3 stabilizes both active and inactive forms of Dmc1 filaments independently of its impact on ATP hydrolysis.
1. Nucleic Acids Res - published October 2, 2025
2. Chan YL, Reitz D, Budke B, Rice PA, Bishop DK
How many (distinguishable) classes can we identify in single-particle analysis?
1. Acta Crystallogr D Struct Biol - published October 1, 2025
2. Lauzirika O, Pernica M, Herreros D, Ramírez-Aportela E, Krieger J, Gragera M, Iceta M, Conesa P, Fonseca Y, Jiménez J, Filipovic J, Carazo JM, Sorzano COS
Genetic code expansion and enzymatic modifications as accessible methods for studying site-specific post-translational modifications of alpha-synuclein and tau.
1. Protein Sci - published October 1, 2025
2. Saleh IG, Shimogawa M, Ramirez J, Abakah B, Venkatesh Y, James HP, Li MH, Louie SA, Lougee MG, Chia WK, Brue C, Cooley RB, Mehl RA, Baumgart T, Mach RH, Eliezer D, Rhoades E, Petersson EJ
The C-terminal extension of calprotectin mediates zinc chelation and modulates Staphylococcus aureus biomass accumulation.
1. Protein Sci - published October 1, 2025
2. Perera YR, Enriquez KT, Rodriguez A, Garcia V, Akizuki T, Naretto A, Togashi M, Guillen R, Skaar EP, Chazin WJ
Visions of the future of molecular cell biology.
1. Nat Rev Mol Cell Biol - published October 1, 2025
2. Abu-Remaileh M, Chan CJ, Chen L, Demirer GS, Fiszbein A, Jug F, Lechuga-Vieco AV, Luisier R, Pagan J, Sabari BR, Shao S, Sun L, Żylicz JJ
Structural insights into the Pseudomonas aeruginosa ClpP1•ClpP2 heterocomplex and its interactions with the AAA+ ClpX unfoldase.
1. Protein Sci - published October 1, 2025
2. Ghanbarpour A, Zhang JJ, Davis JH, Baker TA, Sauer RT
aHSCs-targeted bimetallic nanozymes and luteolin-loaded liposomes: Synergistic reversal of liver fibrosis via antioxidant, cellular senescence, and cellular apoptotic mechanisms.
1. Mater Today Bio - published October 1, 2025
2. Sun Z, Liang C, Zhao Y, Wu J, Wen L, Liu X, Shi M, Li X
Mechanisms of Messenger RNA Packaging and Export.
1. Annu Rev Cell Dev Biol - published October 1, 2025
2. Faraway R, Zenklusen D, Plaschka C
Structural and mechanistic insights into Dis3L2-mediated degradation of structured RNA.
1. RNA - published October 1, 2025
2. Matos RG, Garg A, Costa SM, Pereira P, Arraiano CM, Joshua-Tor L, Viegas SC
Apolipoprotein A5 Reduces Clearance of Very Low-density Lipoprotein by Altering Apolipoprotein E Content.
1. J Lipid Res - published October 1, 2025
2. Tarapore P, Swertfeger D, Morris J, He Y, Sarkar S, Melchior JT, Shah AS, Liu M, Davidson WS
Improving B-cell epitope prediction.
1. Drug Discov Today - published October 1, 2025
2. Yu H, Joseph-McCarthy D, Vajda S
Structure and assembly of the A-C linker connecting microtubule triplets in centrioles.
1. Sci Adv - published October 1, 2025
2. Cai B, Xu J, Collet EH, Aarts E, Luo L, Leitner A, Ishikawa T, Beltrao P, Pearson CG, Pilhofer M, Wieczorek M
Pancreatic Damage in Ovarian Cancer-Associated Cachexia Is Driven by Activin A Signalling.
1. J Cachexia Sarcopenia Muscle - published October 1, 2025
2. Abazarikia A, So W, Luan Y, Kattamuri C, Thompson TB, Kim SY
Dipeptidase 1 is a functional receptor for a porcine coronavirus.
1. Nat Microbiol - published October 1, 2025
2. Dufloo J, Fernández I, Arbabian A, Haouz A, Temperton N, Gimenez-Lirola LG, Rey FA, Sanjuán R
LARGE1 processively polymerizes length-controlled matriglycan on prodystroglycan.
1. Nat Commun - published October 1, 2025
2. Joseph S, Schnicker NJ, Spellmon N, Xu Z, Yan R, Yu Z, Davulcu O, Yang T, Hopkins J, Anderson ME, Venzke D, Campbell KP
Mechanism of USP21 autoinhibition and histone H2AK119 deubiquitination.
1. Sci Adv - published October 1, 2025
2. Rahman S, Hicks CW, Gwizdala A, Wolberger C
BTK autoinhibition analyzed by high-throughput swaps of SH2 domains.
1. Proc Natl Acad Sci U S A - published October 1, 2025
2. Eisen TJ, Ghaffari-Kashani S, Hung CL, Groves JT, Kuriyan J
Germinal center-mediated broadening of B cell responses to SARS-CoV-2 booster immunization.
1. Sci Immunol - published October 1, 2025
2. Malladi SK, Jaiswal D, Ying B, Alsoussi WB, Darling TL, Dadonaite B, Civljak A, Horvath SC, Zhou JQ, Kim W, Turner JS, Schmitz AJ, Han F, Scheaffer SM, Farnsworth CW, Nachbagauer R, Nestorova B, Chalkias S, Klebert MK, Edwards DK, Paris R, Strnad BS, Middleton WD, O'Halloran JA, Presti RM, Bloom JD, Boon ACM, Diamond MS, Bajic G, Ellebedy AH
Donor strand complementation and calcium ion coordination drive the chaperone-free polymerization of archaeal cannulae.
1. Nat Commun - published October 1, 2025
2. Sleutel M, Sonani RR, Miller JG, Wang F, Gonzalez Socorro A, Chen Y, Martin R, Demeler B, Rudolph MJ, Alva V, Remaut H, Egelman EH, Conticello VP
Hantavirus Gn(H) Nanoparticle Immunogen Elicits a Cross-Neutralizing Antibody Response in Mice.
1. ACS Infect Dis - published October 1, 2025
2. Ramos KE, Mariano MC, Mittler E, Pardo R, Zylberman V, Guardado-Calvo P, Chandran K, Lai JR
Proteomic analysis of metabolic adaptation in a unicellular cyanobacterium during light-dark cycles and nitrogen fixation.
1. Sci Rep - published October 1, 2025
2. Panda P, Giri SJ, Thirumalaikumar VP, Sherman LA, Kihara D, Aryal UK
A Universal Spectrum Annotator for Complex Peptidoforms in Mass Spectrometry-Based Proteomics.
1. Anal Chem - published October 1, 2025
2. Schulte D, Leuvenink RW, Jager S, Heck AJR, Snijder J
TREM2-apoE3 interactions and Alzheimer's disease: Molecular and structural insights and effects of TREM2 R47H and apoE4 variants.
1. Alzheimers Dement - published October 1, 2025
2. Greer RA, Tuckey RA, Dean HB, Brett TJ, Roberson ED, Song Y
Cross-neutralizing and potent human monoclonal antibodies against historical and emerging H5Nx influenza viruses.
1. Nat Microbiol - published October 1, 2025
2. Abu-Shmais AA, Freeman G, Creanga A, Vukovich MJ, Malla T, Mantus GE, Shimberg GD, Gillespie RA, Guerra Canedo V, Dadonaite B, Rodgers MD, Chopde AJ, Bardwil-Lugones E, Bylund T, Henry AR, Roberts-Torres J, Johnston TS, Smith S, Yang ES, Cheng C, Walker EL, Ravichandran M, Gordon IJ, Dittakavi TS, Reed DS, Pierson TC, Dropulic L, Bloom JD, Tsybovsky Y, Boritz EA, Douek DC, Zhou T, Kanekiyo M, Andrews SF
Practical Outcomes From CASP16 for Users in Need of Biomolecular Structure Prediction.
1. Proteins - published October 1, 2025
2. Abriata LA, Dal Peraro M
Water-detected NMR allows dynamic observations of repeat-expansion RNA condensates.
1. Nat Chem - published October 1, 2025
2. Schmoll J, Novakovic M, Allain FH
Mechanisms of assembly and function of the Hsp70-Hsp40 chaperone machinery.
1. Mol Cell - published October 1, 2025
2. Jiang Y, Ibrahim Z, Xia Y, Clay M, Myasnikov A, Immadisetty K, Xia Z, Tang L, Rossi P, Ganguly P, Liu J, Miller D, Che M, Palacios SM, Kramer G, Bukau B, Kalodimos CG
Ultrapotent human antibodies lock E protein dimers central region of diverse DENV3 morphological variants.
1. Nat Commun - published October 1, 2025
2. Fibriansah G, Ng TS, Lim XN, Shebanova A, Ng LC, Tan SL, Tan AWK, Shi J, Crowe JE Jr, Lok SM
The Kaposi's sarcoma-associated herpesvirus TBP mimic uses a noncanonical DNA-binding mode to promote viral late gene transcription.
1. Nucleic Acids Res - published October 1, 2025
2. Llacsahuanga-Allcca LE, Didychuk AL, Rodríguez-Vargas A, Glaunsinger BA
High-throughput discovery of transmembrane helix dimers from human single-pass membrane proteins with TOXGREEN sort-seq.
1. PNAS Nexus - published October 1, 2025
2. Anderson SM, Choi J, Cushman EM, Leander M, Raman S, Senes A
Systematic genome-wide mapping of host determinants of bacteriophage infectivity.
1. Cell Syst - published October 1, 2025
2. Chitboonthavisuk C, Martin C, Huss P, Peters JM, Anantharaman K, Raman S
FASTK post-transcriptional regulators - a 'FAST-tracK' in mitochondrial gene expression.
1. Biochem Soc Trans - published October 1, 2025
2. Van Riper J, Corsaro BJ, Pillon MC
Bat sarbecovirus WIV1-CoV bears an adaptive mutation that alters spike dynamics and enhances ACE2 binding.
1. PLoS Pathog - published October 1, 2025
2. Tse AL, Lasso G, Berrigan J, McLellan JS, Chandran K, Miller EH
Comprehensive Analysis of the Impact of Climate Change and Human Activities on the Distribution of Five Fritillaria Species Using the Optimized Maxent Model.
1. Ecol Evol - published October 1, 2025
2. Li Y, Wang Q, Ding R, Liu X, Liu S, Bai J, Niu S, Guo J
Decoding nucleoside supplementation: how thymidine outperforms ribonucleosides in accelerating mammalian replication forks.
1. Nucleic Acids Res - published October 1, 2025
2. Pandey P, Kurashima K, Bylund G, Johansson E, Tsubouchi T, Chabes A
Discovery of a Cryptic Pocket in EcDsbA Opens New Opportunities for Antibacterial Discovery.
1. Angew Chem Int Ed Engl - published October 1, 2025
2. Mohanty B, Alwan WS, Gunzburg MJ, Ilyichova O, Williams ML, Sharma G, Wang G, Heras B, Fenwick RB, Wright PE, Vallurapalli P, Doak BC, Capuano B, Scanlon MJ
misteINK: a protein nanocage-based ink with reversible, stimuli-responsive color shifts.
1. Biomater Sci - published October 1, 2025
2. Yamashita M, Kawakami N, Arai R, Ikeda A, Moriya T, Senda T, Miyamoto K
Embryonic stem cell-derived extracellular vesicles delay cellular senescence by inhibiting oxidative stress.
1. J Biol Chem - published October 1, 2025
2. Enomoto S, Hur YH, Solodova T, Neumann J, Cerione RA, Antonyak MA
Viral Interference of Nucleocytoplasmic Transport.
1. J Biol Chem - published October 1, 2025
2. Chien CY, Mobbs GW, Ehrenkranz J, Hoelz A
Increased percentages of circulating T follicular helper cells associate with disease subtype and activity in pediatric immune cytopenias.
1. Haematologica - published October 1, 2025
2. Harris EM, Bourdine A, Magin L, Elkins M, Nikiciuk M, Chu A, Wafadari D, Nastasio S, Hale R, Senkpeil L, Rockowitz S, Sliz P, Platt CD, LaBere B, Montcrieff C, Chamseddine S, Ohsumi TK, Grace RF, Chou J
HBV p22-interacting protein C1QBP inhibits viral replication through impeding nucleocapsid formation and nuclear import.
1. PLoS Pathog - published October 1, 2025
2. Peng X, Liu CD, Mitra B, Kim ES, Sun N, Jurado A, Zhang H, Li S, Zhou T, Guo H
Phosphorylation as a candidate regulatory mechanism for effector recruitment to tankyrase.
1. R Soc Open Sci - published October 1, 2025
2. Broadway BJ, Pollock K, Cronin N, Rottapel R, Sicheri F, Guettler S
Sortase-mediated ligation of cytochrome c peroxidase and cytochrome c highlights the roles of dynamics and conformational specificity for interprotein electron transfer.
1. J Inorg Biochem - published October 1, 2025
2. Zawistowski RK, Clark JC, Crane BR
Selenium Exerts Antimicrobial Activity against the Perinatal Pathogen Streptococcus agalactiae and Perturbs Bacterial Interactions with Human Gestational Membranes.
1. ACS Bio Med Chem Au - published October 1, 2025
2. Chinni R, Horner K, Avila W, Manning SD, Gaddy JA, Damo S
Biochemical and Structural Analyses of the Tardigrade DNA-Damage Suppressor Protein, Dsup.
1. J Mol Biol - published October 1, 2025
2. Woodward TJ, Washington MT
Ten rules for a structural bioinformatic analysis.
1. PLoS Comput Biol - published October 1, 2025
2. Wankowicz SA
Workflow Using a Cryogenic Coincident Fluorescence, Electron, and Ion Beam Microscope for Targeted Milling of Cells.
1. J Vis Exp - published October 1, 2025
2. Wang J, Sica AV, Jensen GJ, Dahlberg PD