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40 Member Publications for September 2025

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Structure, function and assembly of nuclear pore complexes.
1. Nat Rev Mol Cell Biol - published September 9, 2025
2. Petrovic S, Mobbs GW, Hoelz A
Phenotypic pleiotropy of missense variants in human B cell confinement receptor P2RY8.
1. Cell Genom - published September 9, 2025
2. LaFlam TN, Billesbølle CB, Dinh T, Wolfreys FD, Lu E, Matteson T, An J, Xu Y, Singhal A, Brandes N, Ntranos V, Manglik A, Cyster JG, Ye CJ
Repeated emergence of giant microRNA hairpins across invertebrates.
1. Cell Rep - published September 9, 2025
2. Javad-Zada MM, Zou X, Okamura K, Shang R, Garg A, Lee E, Joshua-Tor L, Fromm B, Lai EC
Iron-oxide nanoparticles selectively enhance the toxicity of pharmacological ascorbate through hydrogen peroxide-dependent DNA damage in non-small cell lung cancer (NSCLC).
1. Free Radic Biol Med - published September 9, 2025
2. Singhania M, Sho S, Fath MA, Sanchez A, Pulliam CF, Allen BG, Buettner GR, Goswami PC, Spies M, Petronek MS, Spitz DR
The Discovery of RP-2119: A Potent, Selective, and Orally Bioavailable Polθ ATPase Inhibitor.
1. J Med Chem - published September 8, 2025
2. Mochirian P, Papp R, Mathieu MC, Ferraro GB, Dietrich E, Liu B, Bendahan D, Perryman AL, Surprenant S, Fournier S, Barzili BL, Bonneau-Fortin A, Yin SY, Leclaire ME, Patel C, Poirier H, Save S, Mathieu Y, Morin N, Godbout C, Burston HE, Zahn KE, Attia MA, Pinter T, Barabé F, Parikh P, Jagani C, Kang G, Scapin G, Mamane Y, Sfeir A, Mader P, Sicheri F, Zimmermann M, Roulston A, Morris SJ, Black WC, Gallant M
Functional Dissection of the zDHHC Palmitoyltransferase 5-Golgin A7 Palmitoylation Complex.
1. J Biol Chem - published September 8, 2025
2. Kahlson MA, Ritho J, Gomes JV, Wang H, Butterwick JA, Dixon SJ
Michaelis-Menten kinetics of RasGAP proteins by a rapid fluorescence-based assay.
1. Methods - published September 8, 2025
2. Paul ME, Vish KJ, Boggon TJ
Selective targeting of TBXT with DARPins identifies regulatory networks and therapeutic vulnerabilities in chordoma.
1. Sci Adv - published September 5, 2025
2. Umbaugh CS, Groth M, Erkut C, Lee KS, Marinho J, Linder S, Iser F, Kapp JN, Schroeter P, Dolaner S, Kayserili A, Helm D, Schneider M, Hartmann J, Walch P, Barth TFE, Mellert K, Dreier B, Schaefer JV, Plückthun A, Fröhling S, Scholl C
Photoaffinity Labeling Reveals a Role for the Unusual Triply Acylated Phospholipid N-Acylphosphatidylethanolamine in Lactate Homeostasis.
1. J Am Chem Soc - published September 5, 2025
2. Chiu DC, Cho YT, Lin H, Baskin JM
ESCMID workshop: Artificial Intelligence and Machine Learning in Medical Microbiology Diagnostics.
1. Microbes Infect - published September 5, 2025
2. Greutmann M, Borgwardt K, Brüningk S, Franzeck F, Giske CG, Green AG, Guerrero-López A, Ip M, Jutzeler C, Kahles A, Krauthammer M, Macesic N, McFadden B, Meijer E, Moore N, Moran-Gilad J, Lboukili I, Nolte O, Patel R, Schneider G, Seeger MA, Sethi T, Skov RL, Yoon CH, Rodríguez-Sánchez B, Egli A
Genetic suppression of precocious transcription termination identifies mutations in essential subunits of the fission yeast cleavage and polyadenylation machinery.
1. RNA - published September 4, 2025
2. Innokentev A, Sanchez AM, Bednor L, Babor J, Schwer B, Shuman S
Functional Relevance of CASP16 Nucleic Acid Predictions as Evaluated by Structure Providers.
1. Proteins - published September 4, 2025
2. Kretsch RC, Albrecht R, Andersen ES, Chen HA, Chiu W, Das R, Gezelle JG, Hartmann MD, Höbartner C, Hu Y, Jadhav S, Johnson PE, Jones CP, Koirala D, Kristoffersen EL, Largy E, Lewicka A, Mackereth CD, Marcia M, Nigro M, Ojha M, Piccirilli JA, Rice PA, Shin H, Steckelberg AL, Su Z, Srivastava Y, Wang L, Wu Y, Xie J, Zwergius NH, Moult J, Kryshtafovych A
Target RNA recognition drives PIWI(∗) complex assembly for transposon silencing.
1. Mol Cell - published September 4, 2025
2. Portell-Montserrat J, Tirian L, Yu C, Silvestri G, Hohmann U, Handler D, Duchek P, Fin L, Plaschka C, Brennecke J
18-Crown-6-ether Utilizes Distinct Allosteric Interactions to Uncouple Transport by the Multidrug Efflux Pump EmrE.
1. Biochemistry - published September 3, 2025
2. Brousseau M, Dash T, Rourke MJ, Kurauskas V, Tonelli M, Hibbs KM, Buller AR, Marty MT, Henzler-Wildman KA
Reconstitution of autophagic-like membrane tethering reveals that Atg11 can bind and cluster vesicles on cargo mimetics.
1. Autophagy - published September 3, 2025
2. Andhare D, Katzenell S, Najera SI, Mauras SC, Bauer KM, Ragusa MJ
Targeting necrotic lipid release in tumors enhances immunosurveillance and cancer immunotherapy of glioblastoma.
1. Cell Res - published September 3, 2025
2. Ji Y, Jiang J, Hu L, Lin P, Zhou M, Hu S, Wang M, Ji Y, Liu X, Yan D, Guo Y, Sathe AA, Evers BM, Xing C, Luo X, Xie Q, Pei W, Zhang Z, Yu H
The XBB.1.5 COVID-19 vaccine elicits a durable antibody response to ancestral and XBB.1.5 SARS-CoV-2 spike proteins.
1. Sci Transl Med - published September 3, 2025
2. Kumar S, Jain S, Wali B, Zarnitsyna VI, Joshi D, Ellis ML, Lai L, Malik AA, McPherson TO, Godbole S, Patel A, Linderman S, Solis D, Sahoo MK, Bechnak K, Paredes I, Tanios R, Kazzi B, Dib SM, Litvack MB, Wimalasena ST, Hicks H, Tamin A, Bowen NE, Atherton L, Paden C, Harcourt JL, Wentworth DE, Ciric C, West RH, Rostad CA, Teng IT, Wang D, Ortlund EA, Menachery VD, Edupuganti S, Kwong PD, Rouphael N, Pinsky BA, Douek DC, Moreno A, Wrammert J, Suthar MS
SHP2 genetic variants in NSML-associated RASopathies disrupt the PZR-IRX transcription factor signaling axis.
1. Proc Natl Acad Sci U S A - published September 2, 2025
2. Perla S, Stiegler AL, Yi JS, Enyenihi L, Zhang L, Riaz M, An E, Qyang Y, Boggon TJ, Bennett AM
Nucleotide- and metalloid-driven conformational changes in the arsenite efflux ATPase ArsA.
1. Proc Natl Acad Sci U S A - published September 2, 2025
2. Mahajan S, Pall AE, Li YE, Stemmler TL, Rees DC, Clemons WM Jr
Structural insights into the vitamin K-dependent γ-carboxylation of osteocalcin.
1. Cell Res - published September 2, 2025
2. Cao Q, Fan J, Ammerman A, Awasthi S, Lin Z, Mierxiati S, Chen H, Xu J, Garcia BA, Liu B, Li W
Chromosome-scale genome assembly and gene annotation of the hydrothermal vent annelid Alvinella pompejana yield insight into animal evolution in extreme environments.
1. BMC Biol - published September 2, 2025
2. Hilali SE, Dru P, Le Moan A, Li YI, Huynen MA, Hoelz A, Robinson RC, Martín-Durán JM, Jollivet D, Claridge-Chang A, Copley RR
Global Longitudinal Strain: A Potential Noninvasive Tool for Early Detection of Radiation-Induced Cardiac Dysfunction in Patients With Lung Cancer Receiving Thoracic Radiation Therapy.
1. Int J Radiat Oncol Biol Phys - published September 1, 2025
2. Montalvo SK, Lue B, Kakadiaris E, Ahn C, Zhang-Velten E, Aliru M, Lu W, Westover KD, Iyengar P, Timmerman RD, Zaha VG, Vallabhaneni S, Zhang K, Chandra A, Alluri PG
Recent synthetic methodology advancements towards all-carbon quaternary center formation and applications.
1. Tetrahedron - published September 1, 2025
2. Ling T, Garfias JM, Lawson SL, Rivas F
Nodal modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation.
1. J Cell Biol - published September 1, 2025
2. Naughton BS, Devarkar SC, Todorow V, Mallik S, Oxendine S, Junnarkar S, Ren Y, Berro J, Kirstein J, Xiong Y, Schlieker C
Mechano-chemical encapsulation of gemcitabine hydrochloride on metal-organic framework, preparation of shaped pellets, delayed drug release, and time-dependent toxicity to PANC-1 cancer cells.
1. J Drug Deliv Sci Technol - published September 1, 2025
2. Umar S, Catazaro J, Wachira J, Samokhvalov A
Computational structure prediction of lanthipeptides with NMR data reveals underappreciated peptide flexibility.
1. Protein Sci - published September 1, 2025
2. Tydings CW, Meiler J, Walker AS
AlphaFold model quality self-assessment improvement via deep graph learning.
1. Protein Sci - published September 1, 2025
2. Verburgt J, Zhang Z, Kihara D
Cryo-EM structures of CRAF/MEK1/14-3-3 complexes in autoinhibited and open-monomer states reveal features of RAF regulation.
1. Nat Commun - published September 1, 2025
2. Jang DM, Boxer K, Ha BH, Tkacik E, Levitz T, Rawson S, Metivier RJ, Schmoker A, Jeon H, Eck MJ
DeepSCEM: A User-Friendly Solution for Deep Learning-Based Image Segmentation in Cellular Electron Microscopy.
1. Biol Cell - published September 1, 2025
2. Meyer C, Hanss V, Baudrier E, Naegel B, Schultz P
Pharmacologic interrogation of USP28 cellular function in p53 signaling.
1. Cell Chem Biol - published September 1, 2025
2. Bratt AS, Kilgas S, Tarazona Guzman MI, Magin RS, Jaen Maisonet I, Starnbach CA, Teh WP, Varca AC, Hu B, Tarazona Guzman E, Seo HS, Dhe-Paganon S, Girardi NM, Adelmant G, Marto JA, Chowdhury D, Buhrlage SJ
The aflatoxin B(1)-induced formamidopyrimidine adduct is repaired by transcription-coupled nucleotide excision repair in human cells.
1. NAR Cancer - published September 1, 2025
2. Laverty DJ, Tomar R, Erlich S, Stone MP, Nagel ZD
Female membrane proteins regulate postmating ovulation in Drosophila melanogaster by ovulin-dependent and -independent pathways.
1. Proc Natl Acad Sci U S A - published September 1, 2025
2. Yang M, White MA, Findlay GD, Vignogna RC, Apger-McGlaughon J, Clark NL, Choi JY, Fromme JC, Wolfner MF
Biliary Tract Cancers, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology.
1. J Natl Compr Canc Netw - published September 1, 2025
2. Benson AB 3rd, D'Angelica MI, Abrams T, Ahmed A, Akce M, Anaya DA, Anders R, Are C, Aye L, Bachini M, Baker M, Binder D, Brown DB, Burgoyne A, Castellanos J, Cloyd J, Cullinan D, Franses J, Glazer ES, Harris W, Iyer R, Jennings L, Kelley RK, Khan S, Levine M, Melstrom L, Palta M, Raman S, Ronnekleiv-Kelly S, Sahai V, Stein S, Stephans K, Thanikachalam K, Turk A, Vauthey JN, Venook AP, Yano M, Yopp A, Zhao K, Schonfeld R, Hochstetler C
Functional, immunogenetic, and structural convergence in influenza immunity between humans and macaques.
1. Sci Transl Med - published September 1, 2025
2. Sangesland M, Li N, Tsybovsky Y, Rodgers MD, Han J, Rodriguez AJ, Ferguson JA, Henry AR, Smith SC, Roberts-Torres J, Gillespie RA, Liu C, Merriam JS, Stephens T, Williams C, Walker E, Corcoran M, Ravichandran M, Creanga A, Andrews SF, Pierson TC, Karlsson Hedestam GB, Schramm CA, Reed DS, Douek DC, Zhou T, Ward AB, Kanekiyo M
Stabilizing effect of amino acids on protein and colloidal dispersions.
1. Nature - published September 1, 2025
2. Mao T, Xu X, Winkler PM, Siri C, Poliukhina E, Silva PJ, Xu N, Hu Y, Al Zahabi K, La Polla R, Luo Z, Ong Q, Alexander-Katz A, Stellacci F
The Lasker~Koshland Special Achievement Award in Medical Science awarded to Lucy Shapiro.
1. Proc Natl Acad Sci U S A - published September 1, 2025
2. Vosshall LB
α-Synuclein aggregates inhibit ESCRT-III through sequestration and collateral degradation.
1. Mol Cell - published September 1, 2025
2. Sitron CS, Trinkaus VA, Galesic A, Garhammer M, Yuste-Checa P, Dransfeld U, Feigenbutz D, Zhang J, Ivashko L, Dudanova I, Harper JW, Hartl FU
Cage Amine Superbases: Synthesis and Studies of Nona(ethylene)Hexamine and Dodeka(ethylene)Octamine.
1. Chemistry - published September 1, 2025
2. Tan KV, Duong DQ, White KF, Smith BJ, Barnard PJ
Treatment of a severe vascular disease using a bespoke CRISPR-Cas9 base editor in mice.
1. Nat Biomed Eng - published September 1, 2025
2. Alves CRR, Das S, Krishnan V, Ha LL, Fox LR, Stutzman HE, Shamber CE, Kalailingam P, McCarthy S, Lino Cardenas CL, Fong CE, Imai T, Mitra S, Yun S, Wood RK, Benning FMC, Roh K, Lawton J, Kim N, Silverstein RA, Ferreira da Silva J, de la Cruz D, Richa R, Xie J, Gray-Edwards HL, Malhotra R, Chung DY, Chao LH, Tsai SQ, Maguire CA, Lindsay ME, Kleinstiver BP, Musolino PL
Environmental and genetic risk factors of depression converge on neuronal dysfunction driven by changes in cholesterol homeostasis.
1. Dev Cell - published September 1, 2025
2. Oberst P, Xu N, Munguba H, Zhang C, Zhong A, Zhou T, Liston C, Levitz J, Studer L